Summary information and primary citation
- PDB-id
-
4lg7;
DSSR-derived features in text and
JSON formats; DNAproDB
- Class
- hydrolase-DNA
- Method
- X-ray (2.5 Å)
- Summary
- Crystal structure mbd4 mbd domain in complex with
methylated cpg DNA
- Reference
- Xu C, Tempel W, Wernimont AK, Bountra C, Arrowsmith CH,
Edwards AM, Min J: "Crystal structure MBD4 MBD domain in
complex with methylated CpG DNA."
- Abstract
-
List of 2 5mC-amino acid contacts
- The contacts include paired nucleotides (mostly a G in
Watson-Crick G-C pairing) and amino-acids within a 4.5-Å
distance cutoff to base atoms of 5mC.
- The structure is oriented in the base reference frame
of 5mC, allowing for easy comparison and direct
superimposition between entries.
- The black sphere (•) denotes the
5-methyl carbon atom in 5mC.
No. 1 B.5CM6: stacking-with-A.ARG119
is-WC-paired is-in-duplex [+]:AcG/cGT
No. 2 C.5CM6: stacking-with-A.ARG97
is-WC-paired is-in-duplex [-]:cGT/AcG
