SNAP-annotated 5mC-DNA-protein interactions: PDB entry 5emc

PDB-id

5emc; DSSR-derived features in text and JSON formats; DNAproDB

Class

transcription-DNA

Method

X-ray (2.3 Å)

Summary

Transcription factor grdbd and smgre complex

Reference

Jin J, Lian T, SU XD: "The effects of cytosine methylation on general transcription factors."

Abstract

 

• The contacts include paired nucleotides (mostly a G in Watson-Crick G-C pairing) and amino-acids within a 4.5-Å distance cutoff to base atoms of 5mC.
• The structure is oriented in the base reference frame of 5mC, allowing for easy comparison and direct superimposition between entries.
• The black sphere (•) denotes the 5-methyl carbon atom in 5mC.