|
1a1t
|
viral protein-RNA |
NMR |
De Guzman RN, Wu ZR, Stalling CC, Pappalardo L, Borer
PN, Summers MF |
(1998) "Structure
of the HIV-1 nucleocapsid protein bound to the SL3
psi-RNA recognition element." Science,
279, 384-388. doi: 10.1126/science.279.5349.384.
|
Structure of the hiv-1 nucleocapsid protein bound to
the sl3 psi-RNA recognition element, NMR, 25 structures
. SNAP output
|
|
1a34
|
virus-RNA |
X-ray (1.81 Å) |
Larson SB, Day J, Greenwood A, McPherson A |
(1998) "Refined
structure of satellite tobacco mosaic virus at 1.8 A
resolution." J.Mol.Biol.,
277, 37-59. doi: 10.1006/jmbi.1997.1570.
|
Satellite tobacco mosaic virus-RNA complex . SNAP output
|
|
1a4t
|
transcription-RNA |
NMR |
Cai Z, Gorin A, Frederick R, Ye X, Hu W, Majumdar A,
Kettani A, Patel DJ |
(1998) "Solution
structure of P22 transcriptional antitermination N
peptide-boxB RNA complex."
Nat.Struct.Biol., 5, 203-212.
doi: 10.1038/nsb0398-203.
|
Solution structure of phage p22 n peptide-box b RNA
complex, NMR, 20 structures . SNAP output
|
|
1a9n
|
RNA binding protein-RNA |
X-ray (2.38 Å) |
Price SR, Evans PR, Nagai K |
(1998) "Crystal
structure of the spliceosomal U2B"-U2A' protein complex
bound to a fragment of U2 small nuclear RNA."
Nature, 394, 645-650. doi:
10.1038/29234.
|
Crystal structure of the spliceosomal u2b''-u2a'
protein complex bound to a fragment of u2 small nuclear
RNA . SNAP output
|
|
1aq3
|
virus-RNA |
X-ray (2.8 Å) |
van den Worm SH, Stonehouse NJ, Valegard K, Murray
JB, Walton C, Fridborg K, Stockley PG, Liljas L |
(1998) "Crystal
structures of MS2 coat protein mutants in complex with
wild-type RNA operator fragments." Nucleic
Acids Res., 26, 1345-1351. doi:
10.1093/nar/26.5.1345.
|
Bacteriophage ms2 capsid protein-RNA complex . SNAP output
|
|
1aq4
|
virus-RNA |
X-ray (3.0 Å) |
van den Worm SH, Stonehouse NJ, Valegard K, Murray
JB, Walton C, Fridborg K, Stockley PG, Liljas L |
(1998) "Crystal
structures of MS2 coat protein mutants in complex with
wild-type RNA operator fragments." Nucleic
Acids Res., 26, 1345-1351. doi:
10.1093/nar/26.5.1345.
|
Structure of a ms2 coat protein mutant in complex with
an RNA operator . SNAP
output
|
|
1asy
|
complex (aminoacyl-trna synthase-trna) |
X-ray (2.9 Å) |
Ruff M, Krishnaswamy S, Boeglin M, Poterszman A,
Mitschler A, Podjarny A, Rees B, Thierry JC, Moras D |
(1991) "Class II
aminoacyl transfer RNA synthetases: crystal structure
of yeast aspartyl-tRNA synthetase complexed with
tRNA(Asp)." Science, 252,
1682-1689.
|
Class ii aminoacyl transfer RNA synthetases: crystal
structure of yeast aspartyl-trna synthetase complexed
with trna asp . SNAP
output
|
|
1asz
|
complex (aminoacyl-trna synthase-trna) |
X-ray (3.0 Å) |
Cavarelli J, Eriani G, Rees B, Ruff M, Boeglin M,
Mitschler A, Martin F, Gangloff J, Thierry JC, Moras
D |
(1994) "The
active site of yeast aspartyl-tRNA synthetase:
structural and functional aspects of the aminoacylation
reaction." EMBO J., 13,
327-337.
|
The active site of yeast aspartyl-trna synthetase:
structural and functional aspects of the aminoacylation
reaction . SNAP
output
|
|
1aud
|
RNA binding protein-RNA |
NMR |
Allain FH, Howe PW, Neuhaus D, Varani G |
(1997) "Structural
basis of the RNA-binding specificity of human U1A
protein." EMBO J., 16,
5764-5774. doi: 10.1093/emboj/16.18.5764.
|
U1a-utrrna, NMR, 31 structures . SNAP output
|
|
1av6
|
transferase-RNA |
X-ray (2.8 Å) |
Hodel AE, Gershon PD, Quiocho FA |
(1998) "Structural
basis for sequence-nonspecific recognition of 5'-capped
mRNA by a cap-modifying enzyme." Mol.Cell,
1, 443-447. doi: 10.1016/S1097-2765(00)80044-1.
|
Vaccinia methyltransferase vp39 complexed with m7g
capped RNA hexamer and s-adenosylhomocysteine .
SNAP output
|
|
1b23
|
gene regulation-RNA |
X-ray (2.6 Å) |
Nissen P, Thirup S, Kjeldgaard M, Nyborg J |
(1999) "The
crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals
general and specific features in the ternary complex
and in tRNA." Structure Fold.Des.,
7, 143-156. doi: 10.1016/S0969-2126(99)80021-5.
|
E. coli cysteinyl-trna and t. aquaticus elongation
factor ef-tu:gtp ternary complex . SNAP output
|
|
1b2m
|
hydrolase-RNA |
X-ray (2.0 Å) |
Arni RK, Watanabe L, Ward RJ, Kreitman RJ, Kumar K,
Walz Jr FG |
(1999) "Three-dimensional
structure of ribonuclease T1 complexed with an
isosteric phosphonate substrate analogue of GpU:
alternate substrate binding modes and catalysis."
Biochemistry, 38, 2452-2461.
doi: 10.1021/bi982612q.
|
Three-dimensional structure of ribonulcease t1
complexed with an isosteric phosphonate analogue of
gpu: alternate substrate binding modes and catalysis. .
SNAP output
|
|
1b7f
|
RNA-binding protein-RNA |
X-ray (2.6 Å) |
Handa N, Nureki O, Kurimoto K, Kim I, Sakamoto H,
Shimura Y, Muto Y, Yokoyama S |
(1999) "Structural
basis for recognition of the tra mRNA precursor by the
Sex-lethal protein." Nature,
398, 579-585. doi: 10.1038/19242.
|
Sxl-lethal protein-RNA complex . SNAP output
|
|
1biv
|
viral protein-RNA |
NMR |
Ye X, Kumar RA, Patel DJ |
(1995) "Molecular
recognition in the bovine immunodeficiency virus Tat
peptide-TAR RNA complex." Chem.Biol.,
2, 827-840. doi: 10.1016/1074-5521(95)90089-6.
|
Bovine immunodeficiency virus tat-tar complex, NMR, 5
structures . SNAP
output
|
|
1bmv
|
virus-RNA |
X-ray (3.0 Å) |
Chen ZG, Stauffacher C, Li Y, Schmidt T, Bomu W,
Kamer G, Shanks M, Lomonossoff G, Johnson JE |
(1989) "Protein-RNA
interactions in an icosahedral virus at 3.0 A
resolution." Science,
245, 154-159.
|
Protein-RNA interactions in an icosahedral virus at 3.0
angstroms resolution . SNAP output
|
|
1c04
|
ribosome |
X-ray (5.0 Å) |
Ban N, Nissen P, Hansen J, Capel M, Moore PB, Steitz
TA |
(1999) "Placement
of protein and RNA structures into a 5 A-resolution map
of the 50S ribosomal subunit." Nature,
400, 841-847. doi: 10.1038/23641.
|
Identification of known protein and RNA structures in a
5 a map of the large ribosomal subunit from haloarcula
marismortui . SNAP
output
|
|
1c0a
|
ligase-RNA |
X-ray (2.4 Å) |
Eiler S, Dock-Bregeon A, Moulinier L, Thierry JC,
Moras D |
(1999) "Synthesis
of aspartyl-tRNA(Asp) in Escherichia coli--a snapshot
of the second step." EMBO J.,
18, 6532-6541. doi: 10.1093/emboj/18.22.6532.
|
Crystal structure of the e. coli aspartyl-trna
synthetase : trnaasp : aspartyl-adenylate complex .
SNAP output
|
|
1c9s
|
RNA binding protein-RNA |
X-ray (1.9 Å) |
Antson AA, Dodson EJ, Dodson G, Greaves RB, Chen X,
Gollnick P |
(1999) "Structure
of the trp RNA-binding attenuation protein, TRAP, bound
to RNA." Nature, 401,
235-242. doi: 10.1038/45730.
|
Crystal structure of a complex of trp RNA-binding
attenuation protein with a 53-base single stranded RNA
containing eleven gag triplets separated by au
dinucleotides . SNAP
output
|
|
1cgm
|
virus |
fiber diffraction |
Wang H, Stubbs G |
(1994) "Structure
determination of cucumber green mottle mosaic virus by
X-ray fiber diffraction. Significance for the evolution
of tobamoviruses." J.Mol.Biol.,
239, 371-384. doi: 10.1006/jmbi.1994.1379.
|
Structure determination of cucumber green mottle mosaic
virus by x-ray fiber diffraction. significance for the
evolution of tobamoviruses . SNAP output
|
|
1cvj
|
gene regulation-RNA |
X-ray (2.6 Å) |
Deo RC, Bonanno JB, Sonenberg N, Burley SK |
(1999) "Recognition
of polyadenylate RNA by the poly(A)-binding
protein." Cell(Cambridge,Mass.),
98, 835-845. doi: 10.1016/S0092-8674(00)81517-2.
|
X-ray crystal structure of the poly(a)-binding protein
in complex with polyadenylate RNA . SNAP output
|
|
1cwp
|
virus-RNA |
X-ray (3.2 Å) |
Speir JA, Munshi S, Wang G, Baker TS, Johnson JE |
(1995) "Structures
of the native and swollen forms of cowpea chlorotic
mottle virus determined by X-ray crystallography and
cryo-electron microscopy." Structure,
3, 63-77. doi: 10.1016/S0969-2126(01)00135-6.
|
Structures of the native and swollen forms of cowpea
chlorotic mottle virus determined by x-ray
crystallography and cryo-electron microscopy . SNAP output
|
|
1d6k
|
ribosome |
NMR |
Stoldt M, Wohnert J, Ohlenschlager O, Gorlach M,
Brown LR |
(1999) "The NMR
structure of the 5S rRNA E-domain-protein L25 complex
shows preformed and induced recognition." EMBO
J., 18, 6508-6521. doi: 10.1093/emboj/18.22.6508.
|
NMR solution structure of the 5s rrna e-loop-l25
complex . SNAP
output
|
|
1d9d
|
transferase-DNA, RNA |
X-ray (2.18 Å) |
Teplova M, Wallace ST, Tereshko V, Minasov G, Symons
AM, Cook PD, Manoharan M, Egli M |
(1999) "Structural
origins of the exonuclease resistance of a zwitterionic
RNA." Proc.Natl.Acad.Sci.USA,
96, 14240-14245. doi: 10.1073/pnas.96.25.14240.
|
Crystall structure of the complex of DNA polymerase i
klenow fragment with short DNA fragment carrying
2'-0-aminopropyl-RNA modifications 5'-d(tcg)-ap(auc)-3'
. SNAP output
|
|
1d9f
|
transferase-DNA, RNA |
X-ray (3.0 Å) |
Teplova M, Wallace ST, Tereshko V, Minasov G, Symons
AM, Cook PD, Manoharan M, Egli M |
(1999) "Structural
origins of the exonuclease resistance of a zwitterionic
RNA." Proc.Natl.Acad.Sci.USA,
96, 14240-14245. doi: 10.1073/pnas.96.25.14240.
|
Crystal structure of the complex of DNA polymerase i
klenow fragment with DNA tetramer carrying
2'-o-(3-aminopropyl)-RNA modification
5'-d(tt)-ap(u)-d(t)-3' . SNAP output
|
|
1ddl
|
virus-RNA |
X-ray (2.7 Å) |
Larson SB, Day J, Canady MA, Greenwood A, McPherson
A |
(2000) "Refined
structure of desmodium yellow mottle tymovirus at 2.7 A
resolution." J.Mol.Biol.,
301, 625-642. doi: 10.1006/jmbi.2000.3983.
|
Desmodium yellow mottle tymovirus . SNAP output
|
|
1dfu
|
ribosome |
X-ray (1.8 Å) |
Lu M, Steitz TA |
(2000) "Structure
of Escherichia coli ribosomal protein L25 complexed
with a 5S rRNA fragment at 1.8-A resolution."
Proc.Natl.Acad.Sci.USA, 97,
2023-2028. doi: 10.1073/pnas.97.5.2023.
|
Crystal structure of e.coli ribosomal protein l25
complexed with a 5s rrna fragment at 1.8 Å resolution .
SNAP output
|
|
1di2
|
RNA binding protein-RNA |
X-ray (1.9 Å) |
Ryter JM, Schultz SC |
(1998) "Molecular
basis of double-stranded RNA-protein interactions:
structure of a dsRNA-binding domain complexed with
dsRNA." EMBO J., 17,
7505-7513. doi: 10.1093/emboj/17.24.7505.
|
Crystal structure of a dsrna-binding domain complexed
with dsrna: molecular basis of double-stranded
RNA-protein interactions . SNAP output
|
|
1dk1
|
ribosome |
X-ray (2.8 Å) |
Nikulin A, Serganov A, Ennifar E, Tishchenko S,
Nevskaya N, Shepard W, Portier C, Garber M, Ehresmann B,
Ehresmann C, Nikonov S, Dumas P |
(2000) "Crystal
structure of the S15-rRNA complex."
Nat.Struct.Biol., 7, 273-277.
doi: 10.1038/74028.
|
Detailed view of a key element of the ribosome
assembly: crystal structure of the s15-rrna complex .
SNAP output
|
|
1drz
|
RNA binding protein-RNA |
X-ray (2.3 Å) |
Ferre-D'Amare AR, Zhou K, Doudna JA |
(1998) "Crystal
structure of a hepatitis delta virus ribozyme."
Nature, 395, 567-574. doi:
10.1038/26912.
|
U1a spliceosomal protein-hepatitis delta virus genomic
ribozyme complex . SNAP
output
|
|
1dul
|
signaling protein-RNA |
X-ray (1.8 Å) |
Batey RT, Rambo RP, Lucast L, Rha B, Doudna JA |
(2000) "Crystal
structure of the ribonucleoprotein core of the signal
recognition particle." Science,
287, 1232-1239. doi: 10.1126/science.287.5456.1232.
|
Structure of the ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
1dz5
|
ribonucleoprotein-RNA |
NMR |
Varani L, Gunderson SI, Mattaj IW, Kay LE, Neuhaus D,
Varani G |
(2000) "The NMR
Structure of the 38kDa U1A Protein-Pie RNA Complex
Reveals the Basis of Cooperativity in Regulation of
Polyadenylation by Human U1A Protein."
Nat.Struct.Biol., 7, 329.
doi: 10.1038/74101.
|
The NMR structure of the 38kda u1a protein-pie RNA
complex reveals the basis of cooperativity in
regulation of polyadenylation by human u1a protein .
SNAP output
|
|
1e7k
|
RNA binding protein |
X-ray (2.9 Å) |
Vidovic I, Nottrott S, Hartmuth K, Luhrmann R, Ficner
R |
(2000) "Crystal
Structure of the Spliceosomal 15.5Kd Protein Bound to a
U4 Snrna Fragment." Mol.Cell,
6, 1331. doi: 10.1016/S1097-2765(00)00131-3.
|
Crystal structure of the spliceosomal 15.5kd protein
bound to a u4 snrna fragment . SNAP output
|
|
1e8o
|
alu ribonucleoprotein particle |
X-ray (3.2 Å) |
Weichenrieder O, Wild K, Strub K, Cusack S |
(2000) "Structure
and Assembly of the Alu Domain of the Mammalian Signal
Recognition Particle." Nature,
408, 167. doi: 10.1038/35041507.
|
Core of the alu domain of the mammalian srp . SNAP output
|
|
1ec6
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Lewis HA, Musunuru K, Jensen KB, Edo C, Chen H,
Darnell RB, Burley SK |
(2000) "Sequence-specific
RNA binding by a Nova KH domain: implications for
paraneoplastic disease and the fragile X syndrome."
Cell(Cambridge,Mass.), 100,
323-332. doi: 10.1016/S0092-8674(00)80668-6.
|
Crystal structure of nova-2 kh3 k-homology RNA-binding
domain bound to 20-mer RNA hairpin . SNAP output
|
|
1efw
|
ligase-RNA |
X-ray (3.0 Å) |
Briand C, Poterszman A, Eiler S, Webster G, Thierry
J, Moras D |
(2000) "An
intermediate step in the recognition of tRNA(Asp) by
aspartyl-tRNA synthetase." J.Mol.Biol.,
299, 1051-1060. doi: 10.1006/jmbi.2000.3819.
|
Crystal structure of aspartyl-trna synthetase from
thermus thermophilus complexed to trnaasp from
escherichia coli . SNAP
output
|
|
1eiy
|
ligase-RNA |
X-ray (3.3 Å) |
Goldgur Y, Mosyak L, Reshetnikova L, Ankilova V,
Lavrik O, Khodyreva S, Safro M |
(1997) "The
crystal structure of phenylalanyl-tRNA synthetase from
thermus thermophilus complexed with cognate
tRNAPhe." Structure, 5,
59-68. doi: 10.1016/S0969-2126(97)00166-4.
|
The crystal structure of phenylalanyl-trna synthetase
from thermus thermophilus complexed with cognate
trnaphe . SNAP
output
|
|
1ekz
|
cell cycle-RNA |
NMR |
Ramos A, Grunert S, Adams J, Micklem DR, Proctor MR,
Freund S, Bycroft M, St Johnston D, Varani G |
(2000) "RNA
recognition by a Staufen double-stranded RNA-binding
domain." EMBO J., 19,
997-1009. doi: 10.1093/emboj/19.5.997.
|
NMR structure of the complex between the third dsrbd
from drosophila staufen and a RNA hairpin . SNAP output
|
|
1eqq
|
replication-RNA |
X-ray (3.2 Å) |
Matsumoto T, Morimoto Y, Shibata N, Kinebuchi T,
Shimamoto N, Tsukihara T, Yasuoka N |
(2000) "Roles of
functional loops and the C-terminal segment of a
single-stranded DNA binding protein elucidated by X-Ray
structure analysis." J.Biochem.(Tokyo),
127, 329-335.
|
Single stranded DNA binding protein and ssDNA complex .
SNAP output
|
|
1etf
|
viral protein-RNA |
NMR |
Battiste JL, Mao H, Rao NS, Tan R, Muhandiram DR, Kay
LE, Frankel AD, Williamson JR |
(1996) "Alpha
helix-RNA major groove recognition in an HIV-1 rev
peptide-RRE RNA complex." Science,
273, 1547-1551.
|
Rev response element (rre) RNA complexed with rev
peptide, NMR, minimized average structure . SNAP output
|
|
1etg
|
viral protein-RNA |
NMR |
Battiste JL, Mao H, Rao NS, Tan R, Muhandiram DR, Kay
LE, Frankel AD, Williamson JR |
(1996) "Alpha
helix-RNA major groove recognition in an HIV-1 rev
peptide-RRE RNA complex." Science,
273, 1547-1551.
|
Rev response element (rre) RNA complexed with rev
peptide, NMR, 19 structures . SNAP output
|
|
1euq
|
ligase-RNA |
X-ray (3.1 Å) |
Sherlin LD, Bullock TL, Newberry KJ, Lipman RS, Hou
YM, Beijer B, Sproat BS, Perona JJ |
(2000) "Influence
of transfer RNA tertiary structure on aminoacylation
efficiency by glutaminyl and cysteinyl-tRNA
synthetases." J.Mol.Biol.,
299, 431-446. doi: 10.1006/jmbi.2000.3749.
|
Crystal structure of glutaminyl-trna synthetase
complexed with a trna-gln mutant and an active-site
inhibitor . SNAP
output
|
|
1euy
|
ligase-RNA |
X-ray (2.6 Å) |
Sherlin LD, Bullock TL, Newberry KJ, Lipman RS, Hou
YM, Beijer B, Sproat BS, Perona JJ |
(2000) "Influence
of transfer RNA tertiary structure on aminoacylation
efficiency by glutaminyl and cysteinyl-tRNA
synthetases." J.Mol.Biol.,
299, 431-446. doi: 10.1006/jmbi.2000.3749.
|
Glutaminyl-trna synthetase complexed with a trna mutant
and an active site inhibitor . SNAP output
|
|
1exd
|
ligase-RNA |
X-ray (2.7 Å) |
Bullock TL, Sherlin LD, Perona JJ |
(2000) "Tertiary
core rearrangements in a tight binding transfer RNA
aptamer." Nat.Struct.Biol.,
7, 497-504. doi: 10.1038/75910.
|
Crystal structure of a tight-binding glutamine trna
bound to glutamine aminoacyl trna synthetase . SNAP output
|
|
1exy
|
RNA binding protein-RNA |
NMR |
Jiang F, Gorin A, Hu W, Majumdar A, Baskerville S, Xu
W, Ellington A, Patel DJ |
(1999) "Anchoring
an extended HTLV-1 Rex peptide within an RNA major
groove containing junctional base triples."
Structure Fold.Des., 7,
1461-1472. doi: 10.1016/S0969-2126(00)88337-9.
|
Solution structure of htlv-1 peptide bound to its RNA
aptamer target . SNAP
output
|
|
1f6u
|
structural protein-RNA |
NMR |
Amarasinghe GK, De Guzman RN, Turner RB, Chancellor
KJ, Wu ZR, Summers MF |
(2000) "NMR
structure of the HIV-1 nucleocapsid protein bound to
stem-loop SL2 of the psi-RNA packaging signal.
Implications for genome recognition."
J.Mol.Biol., 301, 491-511.
doi: 10.1006/jmbi.2000.3979.
|
NMR structure of the hiv-1 nucleocapsid protein bound
to stem-loop sl2 of the psi-RNA packaging signal.
implications for genome recognition . SNAP output
|
|
1f7u
|
ligase-RNA |
X-ray (2.2 Å) |
Delagoutte B, Moras D, Cavarelli J |
(2000) "tRNA
aminoacylation by arginyl-tRNA synthetase: induced
conformations during substrates binding." EMBO
J., 19, 5599-5610. doi: 10.1093/emboj/19.21.5599.
|
Crystal structure of the arginyl-trna synthetase
complexed with the trna(arg) and l-arg . SNAP output
|
|
1f7v
|
ligase-RNA |
X-ray (2.9 Å) |
Delagoutte B, Moras D, Cavarelli J |
(2000) "tRNA
aminoacylation by arginyl-tRNA synthetase: induced
conformations during substrates binding." EMBO
J., 19, 5599-5610. doi: 10.1093/emboj/19.21.5599.
|
Crystal structure of yeast arginyl-trna synthetase
complexed with the trnaarg . SNAP output
|
|
1f7y
|
ribosome |
X-ray (2.8 Å) |
Ennifar E, Nikulin A, Tishchenko S, Serganov A,
Nevskaya N, Garber M, Ehresmann B, Ehresmann C, Nikonov
S, Dumas P |
(2000) "The
crystal structure of UUCG tetraloop."
J.Mol.Biol., 304, 35-42. doi:
10.1006/jmbi.2000.4204.
|
The crystal structure of two uucg loops highlights the
role played by 2'-hydroxyl groups in its unusual
stability . SNAP
output
|
|
1f8v
|
virus-RNA |
X-ray (3.0 Å) |
Tang L, Johnson KN, Ball LA, Lin T, Yeager M, Johnson
JE |
(2001) "The
structure of pariacoto virus reveals a dodecahedral
cage of duplex RNA." Nat.Struct.Biol.,
8, 77-83. doi: 10.1038/83089.
|
The structure of pariacoto virus reveals a dodecahedral
cage of duplex RNA . SNAP output
|
|
1feu
|
ribosome |
X-ray (2.3 Å) |
Fedorov R, Meshcheryakov V, Gongadze G, Fomenkova N,
Nevskaya N, Selmer M, Laurberg M, Kristensen O,
Al-Karadaghi S, Liljas A, Garber M, Nikonov S |
(2001) "Structure
of ribosomal protein TL5 complexed with RNA provides
new insights into the CTC family of stress
proteins." Acta Crystallogr.,Sect.D,
57, 968-976. doi: 10.1107/S0907444901006291.
|
Crystal structure of ribosomal protein tl5, one of the
ctc family proteins, complexed with a fragment of 5s
rrna. . SNAP output
|
|
1ffy
|
ligase-RNA |
X-ray (2.2 Å) |
Silvian LF, Wang J, Steitz TA |
(1999) "Insights
into editing from an ile-tRNA synthetase structure with
tRNAile and mupirocin." Science,
285, 1074-1077. doi: 10.1126/science.285.5430.1074.
|
Insights into editing from an ile-trna synthetase
structure with trna(ile) and mupirocin . SNAP output
|
|
1fje
|
structural protein-RNA |
NMR |
Allain FH, Bouvet P, Dieckmann T, Feigon J |
(2000) "Molecular
basis of sequence-specific recognition of pre-ribosomal
RNA by nucleolin." EMBO J.,
19, 6870-6881. doi: 10.1093/emboj/19.24.6870.
|
Solution structure of nucleolin rbd12 in complex with
snre RNA . SNAP
output
|
|
1fjg
|
ribosome |
X-ray (3.0 Å) |
Carter AP, Clemons Jr WM, Brodersen DE, Morgan-Warren
RJ, Wimberly BT, Ramakrishnan V |
(2000) "Functional
insights from the structure of the 30S ribosomal
subunit and its interactions with antibiotics."
Nature, 407, 340-348. doi:
10.1038/35030019.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in complex with the antibiotics streptomycin,
spectinomycin, and paromomycin . SNAP output
|
|
1fka
|
ribosome |
X-ray (3.3 Å) |
Schluenzen F, Tocilj A, Zarivach R, Harms J,
Gluehmann M, Janell D, Bashan A, Bartels H, Agmon I,
Franceschi F, Yonath A |
(2000) "Structure
of functionally activated small ribosomal subunit at
3.3 angstroms resolution."
Cell(Cambridge,Mass.), 102,
615-623. doi: 10.1016/S0092-8674(00)00084-2.
|
Structure of functionally activated small ribosomal
subunit at 3.3 Å resolution . SNAP output
|
|
1fnx
|
immune system-RNA |
NMR |
Inoue M, Hirao M, Kasashima K, Kim I-S, Kawai G,
Kigawa T, Sakamoto H, Muto Y, Yokoyama S |
(2000) "Solution structure of mouse HuC RNA-binding
domains complexed with an AU-Rich element reveals
determinants of neuronal differentiation." |
Solution structure of the huc rbd1-rbd2 complexed with
the au-rich element . SNAP output
|
|
1fxl
|
transcription-RNA |
X-ray (1.8 Å) |
Wang X, Tanaka Hall TM |
(2001) "Structural
basis for recognition of AU-rich element RNA by the HuD
protein." Nat.Struct.Biol.,
8, 141-145. doi: 10.1038/84131.
|
Crystal structure of hud and au-rich element of the
c-fos RNA . SNAP
output
|
|
1g1x
|
ribosome |
X-ray (2.6 Å) |
Agalarov SC, Sridhar Prasad G, Funke PM, Stout CD,
Williamson JR |
(2000) "Structure
of the S15,S6,S18-rRNA complex: assembly of the 30S
ribosome central domain." Science,
288, 107-112. doi: 10.1126/science.288.5463.107.
|
Structure of ribosomal proteins s15, s6, s18, and 16s
ribosomal RNA . SNAP
output
|
|
1g2e
|
transcription-RNA |
X-ray (2.3 Å) |
Wang X, Tanaka Hall TM |
(2001) "Structural
basis for recognition of AU-rich element RNA by the HuD
protein." Nat.Struct.Biol.,
8, 141-145. doi: 10.1038/84131.
|
Crystal structure of hud and au-rich element of the
tumor necrosis factor alpha RNA . SNAP output
|
|
1g59
|
ligase-RNA |
X-ray (2.4 Å) |
Sekine S, Nureki O, Shimada A, Vassylyev DG, Yokoyama
S |
(2001) "Structural
basis for anticodon recognition by discriminating
glutamyl-tRNA synthetase."
Nat.Struct.Biol., 8, 203-206.
doi: 10.1038/84927.
|
Glutamyl-trna synthetase complexed with trna(glu). .
SNAP output
|
|
1g70
|
viral protein-RNA |
NMR |
Gosser Y, Hermann T, Majumdar A, Hu W, Frederick R,
Jiang F, Xu W, Patel DJ |
(2001) "Peptide-triggered
conformational switch in HIV-1 RRE RNA complexes."
Nat.Struct.Biol., 8, 146-150.
doi: 10.1038/84138.
|
Complex of hiv-1 rre-iib RNA with rsg-1.2 peptide .
SNAP output
|
|
1gax
|
ligase-RNA |
X-ray (2.9 Å) |
Fukai S, Nureki O, Sekine S, Shimada A, Tao J,
Vassylyev DG, Yokoyama S |
(2000) "Structural
basis for double-sieve discrimination of L-valine from
L-isoleucine and L-threonine by the complex of
tRNA(Val) and valyl-tRNA synthetase."
Cell(Cambridge,Mass.), 103,
793-803. doi: 10.1016/S0092-8674(00)00182-3.
|
Crystal structure of thermus thermophilus valyl-trna
synthetase complexed with trna(val) and valyl-adenylate
analogue . SNAP
output
|
|
1gtf
|
RNA binding protein-RNA |
X-ray (1.75 Å) |
Hopcroft NH, Wendt AL, Gollnick P, Antson AA |
(2002) "Specificity
of Trap-RNA Interactions: Crystal Structures of Two
Complexes with Different RNA Sequences." Acta
Crystallogr.,Sect.D, 58, 615.
doi: 10.1107/S0907444902003189.
|
The structure of the trp RNA-binding attenuation
protein (trap) bound to a 53-nucleotide RNA molecule
containing gaguu repeats . SNAP output
|
|
1gtn
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Hopcroft NH, Wendt AL, Gollnick P, Antson AA |
(2002) "Specificity
of Trap-RNA Interactions: Crystal Structures of Two
Complexes with Different RNA Sequences." Acta
Crystallogr.,Sect.D, 58, 615.
doi: 10.1107/S0907444902003189.
|
Structure of the trp RNA-binding attenuation protein
(trap) bound to an RNA molecule containing 11 gagcc
repeats . SNAP
output
|
|
1gtr
|
complex (ligase-trna) |
X-ray (2.5 Å) |
Rould MA, Perona JJ, Steitz TA |
(1991) "Structural
basis of anticodon loop recognition by glutaminyl-tRNA
synthetase." Nature, 352,
213-218. doi: 10.1038/352213a0.
|
Structural basis of anticodon loop recognition by
glutaminyl-trna synthetase . SNAP output
|
|
1gts
|
ligase-RNA |
X-ray (2.8 Å) |
Perona JJ, Rould MA, Steitz TA |
(1993) "Structural
basis for transfer RNA aminoacylation by Escherichia
coli glutaminyl-tRNA synthetase."
Biochemistry, 32, 8758-8771.
doi: 10.1021/bi00085a006.
|
Structural basis for transfer RNA aminoaceylation by
escherichia coli glutaminyl-trna synthetase . SNAP output
|
|
1h2c
|
virus-viral protein |
X-ray (1.6 Å) |
Gomis-Ruth FX, Dessen A, Timmins J, Bracher A,
Kolesnikowa L, Becker S, Klenk HD, Weissenhorn W |
(2003) "The
Matrix Protein Vp40 from Ebola Virus Octamerizes Into
Pore-Like Structures with Specific RNA Binding
Properties." Structure,
11, 423. doi: 10.1016/S0969-2126(03)00050-9.
|
Ebola virus matrix protein vp40 n-terminal domain in
complex with RNA (high-resolution vp40[55-194]
variant). . SNAP
output
|
|
1h2d
|
virus-viral protein |
X-ray (2.6 Å) |
Gomis-Ruth FX, Dessen A, Timmins J, Bracher A,
Kolesnikowa L, Becker S, Klenk HD, Weissenhorn W |
(2003) "The
Matrix Protein Vp40 from Ebola Virus Octamerizes Into
Pore-Like Structures with Specific RNA Binding
Properties." Structure,
11, 423. doi: 10.1016/S0969-2126(03)00050-9.
|
Ebola virus matrix protein vp40 n-terminal domain in
complex with RNA (low-resolution vp40[31-212] variant).
. SNAP output
|
|
1h3e
|
ligase |
X-ray (2.9 Å) |
Yaremchuk A, Kriklivyi I, Tukalo M, Cusack S |
(2002) "Class I
Tyrosyl-tRNA Synthetase Has a Class II Mode or tRNA
Recognition." Embo J.,
21, 3829. doi: 10.1093/EMBOJ/CDF373.
|
Tyrosyl-trna synthetase from thermus thermophilus
complexed with wild-type trnatyr(gua) and with atp and
tyrosinol . SNAP
output
|
|
1h4q
|
aminoacyl-trna synthetase |
X-ray (3.0 Å) |
Yaremchuk A, Tukalo M, Grotli M, Cusack S |
(2001) "A
Succession of Substrate Induced Conformational Changes
Ensures the Amino Acid Specificity of Thermus
Thermophilus Prolyl-tRNA Synthetase: Comparison with
Histidyl-tRNA Synthetase." J.Mol.Biol.,
309, 989. doi: 10.1006/JMBI.2001.4712.
|
Prolyl-trna synthetase from thermus thermophilus
complexed with trnapro(cgg), atp and prolinol .
SNAP output
|
|
1h4s
|
aminoacyl-trna synthetase |
X-ray (2.85 Å) |
Yaremchuk A, Tukalo M, Grotli M, Cusack S |
(2001) "A
Succession of Substrate Induced Conformational Changes
Ensures the Amino Acid Specificity of Thermus
Thermophilus Prolyl-tRNA Synthetase: Comparison with
Histidyl-tRNA Synthetase." J.Mol.Biol.,
309, 989. doi: 10.1006/JMBI.2001.4712.
|
Prolyl-trna synthetase from thermus thermophilus
complexed with trnapro(cgg) and a prolyl-adenylate
analogue . SNAP
output
|
|
1hc8
|
ribosome |
X-ray (2.8 Å) |
Conn GL, Gittis AG, Lattman EE, Misra VK, Draper
DE |
(2002) "A
Compact RNA Tertiary Structure Contains a Buried
Backbone-K+ Complex." J.Mol.Biol.,
318, 963. doi: 10.1016/S0022-2836(02)00147-X.
|
Crystal structure of a conserved ribosomal protein-RNA
complex . SNAP
output
|
|
1hji
|
bacteriophage hk022 |
NMR |
Faber C, Schaerpf M, Becker T, Sticht H, Roesch
P |
(2001) "The
Structure of the Coliphage Hk022 Nun
Protein-Lambda-Phage Boxb RNA Complex. Implications for
the Mechanism of Transcription Termination."
J.Biol.Chem., 276, 32064.
doi: 10.1074/JBC.M102975200.
|
Bacteriophage hk022 nun-protein-nutboxb-RNA complex .
SNAP output
|
|
1hnw
|
ribosome |
X-ray (3.4 Å) |
Brodersen DE, Clemons Jr WM, Carter AP, Morgan-Warren
RJ, Wimberly BT, Ramakrishnan V |
(2000) "The
structural basis for the action of the antibiotics
tetracycline, pactamycin, and hygromycin B on the 30S
ribosomal subunit." Cell(Cambridge,Mass.),
103, 1143-1154. doi: 10.1016/S0092-8674(00)00216-6.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in complex with tetracycline . SNAP output
|
|
1hnx
|
ribosome |
X-ray (3.4 Å) |
Brodersen DE, Clemons Jr WM, Carter AP, Morgan-Warren
RJ, Wimberly BT, Ramakrishnan V |
(2000) "The
structural basis for the action of the antibiotics
tetracycline, pactamycin, and hygromycin B on the 30S
ribosomal subunit." Cell(Cambridge,Mass.),
103, 1143-1154. doi: 10.1016/S0092-8674(00)00216-6.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in complex with pactamycin . SNAP output
|
|
1hnz
|
ribosome |
X-ray (3.3 Å) |
Brodersen DE, Clemons Jr WM, Carter AP, Morgan-Warren
RJ, Wimberly BT, Ramakrishnan V |
(2000) "The
structural basis for the action of the antibiotics
tetracycline, pactamycin, and hygromycin B on the 30S
ribosomal subunit." Cell(Cambridge,Mass.),
103, 1143-1154. doi: 10.1016/S0092-8674(00)00216-6.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in complex with hygromycin b . SNAP output
|
|
1hq1
|
signaling protein-RNA |
X-ray (1.52 Å) |
Batey RT, Sagar MB, Doudna JA |
(2001) "Structural
and energetic analysis of RNA recognition by a
universally conserved protein from the signal
recognition particle." J.Mol.Biol.,
307, 229-246. doi: 10.1006/jmbi.2000.4454.
|
Structural and energetic analysis of RNA recognition by
a universally conserved protein from the signal
recognition particle . SNAP output
|
|
1hr0
|
ribosome |
X-ray (3.2 Å) |
Carter AP, Clemons Jr WM, Brodersen DE, Morgan-Warren
RJ, Hartsch T, Wimberly BT, Ramakrishnan V |
(2001) "Crystal
structure of an initiation factor bound to the 30S
ribosomal subunit." Science,
291, 498-501. doi: 10.1126/science.1057766.
|
Crystal structure of initiation factor if1 bound to the
30s ribosomal subunit . SNAP output
|
|
1hvu
|
transferase-RNA |
X-ray (4.75 Å) |
Jaeger J, Restle T, Steitz TA |
(1998) "The
structure of HIV-1 reverse transcriptase complexed with
an RNA pseudoknot inhibitor." EMBO J.,
17, 4535-4542. doi: 10.1093/emboj/17.15.4535.
|
Human immunodeficiency virus type 1 reverse
transcriptase complexed with a 33-base nucleotide RNA
pseudoknot . SNAP
output
|
|
1i5l
|
RNA binding protein-RNA |
X-ray (2.75 Å) |
Toro I, Thore S, Mayer C, Basquin J, Seraphin B, Suck
D |
(2001) "RNA
binding in an Sm core domain: X-ray structure and
functional analysis of an archaeal Sm protein
complex." EMBO J., 20,
2293-2303. doi: 10.1093/emboj/20.9.2293.
|
Crystal structure of an sm-like protein (af-sm1) from
archaeoglobus fulgidus complexed with short poly-u RNA
. SNAP output
|
|
1i6u
|
ribosome |
X-ray (2.6 Å) |
Tishchenko S, Nikulin A, Fomenkova N, Nevskaya N,
Nikonov O, Dumas P, Moine H, Ehresmann B, Ehresmann C,
Piendl W, Lamzin V, Garber M, Nikonov S |
(2001) "Detailed
analysis of RNA-protein interactions within the
ribosomal protein S8-rRNA complex from the archaeon
Methanococcus jannaschii." J.Mol.Biol.,
311, 311-324. doi: 10.1006/jmbi.2001.4877.
|
RNA-protein interactions: the crystal structure of
ribosomal protein s8-rrna complex from methanococcus
jannaschii . SNAP
output
|
|
1i94
|
ribosome |
X-ray (3.2 Å) |
Pioletti M, Schlunzen F, Harms J, Zarivach R,
Gluhmann M, Avila H, Bashan A, Bartels H, Auerbach T,
Jacobi C, Hartsch T, Yonath A, Franceschi F |
(2001) "Crystal
structures of complexes of the small ribosomal subunit
with tetracycline, edeine and IF3." EMBO
J., 20, 1829-1839. doi: 10.1093/emboj/20.8.1829.
|
Crystal structures of the small ribosomal subunit with
tetracycline, edeine and if3 . SNAP output
|
|
1i9f
|
de-novo protein-RNA |
NMR |
Zhang Q, Harada K, Cho HS, Frankel AD, Wemmer DE |
(2001) "Structural
characterization of the complex of the Rev response
element RNA with a selected peptide."
Chem.Biol., 8, 511-520. doi:
10.1016/S1074-5521(01)00027-8.
|
Structural characterization of the complex of the rev
response element RNA with a selected peptide . SNAP output
|
|
1ibk
|
ribosome |
X-ray (3.31 Å) |
Ogle JM, Brodersen DE, Clemons Jr WM, Tarry MJ,
Carter AP, Ramakrishnan V |
(2001) "Recognition
of cognate transfer RNA by the 30S ribosomal
subunit." Science, 292,
897-902. doi: 10.1126/science.1060612.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in complex with the antibiotic paromomycin .
SNAP output
|
|
1ibl
|
ribosome |
X-ray (3.11 Å) |
Ogle JM, Brodersen DE, Clemons Jr WM, Tarry MJ,
Carter AP, Ramakrishnan V |
(2001) "Recognition
of cognate transfer RNA by the 30S ribosomal
subunit." Science, 292,
897-902. doi: 10.1126/science.1060612.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in complex with a messenger RNA fragment and
cognate transfer RNA anticodon stem-loop bound at the a
site and with the antibiotic paromomycin . SNAP output
|
|
1ibm
|
ribosome |
X-ray (3.31 Å) |
Ogle JM, Brodersen DE, Clemons Jr WM, Tarry MJ,
Carter AP, Ramakrishnan V |
(2001) "Recognition
of cognate transfer RNA by the 30S ribosomal
subunit." Science, 292,
897-902. doi: 10.1126/science.1060612.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in complex with a messenger RNA fragment and
cognate transfer RNA anticodon stem-loop bound at the a
site . SNAP output
|
|
1il2
|
ligase-RNA |
X-ray (2.6 Å) |
Moulinier L, Eiler S, Eriani G, Gangloff J, Thierry
JC, Gabriel K, McClain WH, Moras D |
(2001) "The
structure of an AspRS-tRNA(Asp) complex reveals a
tRNA-dependent control mechanism." EMBO
J., 20, 5290-5301. doi: 10.1093/emboj/20.18.5290.
|
Crystal structure of the e. coli aspartyl-trna
synthetase:yeast trnaasp:aspartyl-adenylate complex .
SNAP output
|
|
1ivs
|
ligase-RNA |
X-ray (2.9 Å) |
Fukai S, Nureki O, Sekine S-I, Shimada A, Vassylyev
DG, Yokoyama S |
(2003) "Mechanism
of molecular interactions for tRNA(Val) recognition by
valyl-tRNA synthetase." RNA,
9, 100-111. doi: 10.1261/rna.2760703.
|
Crystal structure of thermus thermophilus valyl-trna
synthetase complexed with trna(val) and valyl-adenylate
analogue . SNAP
output
|
|
1j1u
|
ligase-RNA |
X-ray (1.95 Å) |
Kobayashi T, Nureki O, Ishitani R, Yaremchuk A,
Tukalo M, Cusack S, Sakamoto K, Yokoyama S |
(2003) "Structural
basis for orthogonal tRNA specificities of tyrosyl-tRNA
synthetases for genetic code expansion."
NAT.STRUCT.BIOL., 10,
425-432. doi: 10.1038/nsb934.
|
Crystal structure of archaeal tyrosyl-trna synthetase
complexed with trna(tyr) and l-tyrosine . SNAP output
|
|
1j2b
|
transferase-RNA |
X-ray (3.3 Å) |
Ishitani R, Nureki O, Nameki N, Okada N, Nishimura S,
Yokoyama S |
(2003) "Alternative
Tertiary Structure of tRNA for Recognition by a
Posttranscriptional Modification Enzyme."
Cell(Cambridge,Mass.), 113,
383-394. doi: 10.1016/S0092-8674(03)00280-0.
|
Crystal structure of archaeosine trna-guanine
transglycosylase complexed with lambda-form trna(val) .
SNAP output
|
|
1j5e
|
ribosome |
X-ray (3.05 Å) |
Wimberly BT, Brodersen DE, Clemons Jr WM,
Morgan-Warren RJ, Carter AP, Vonrhein C, Hartsch T,
Ramakrishnan V |
(2000) "Structure
of the 30S ribosomal subunit." Nature,
407, 327-339. doi: 10.1038/35030006.
|
Structure of the thermus thermophilus 30s ribosomal
subunit . SNAP
output
|
|
1jbr
|
hydrolase-RNA |
X-ray (2.15 Å) |
Yang X, Gerczei T, Glover LT, Correll CC |
(2001) "Crystal
structures of restrictocin-inhibitor complexes with
implications for RNA recognition and base
flipping." Nat.Struct.Biol.,
8, 968-973. doi: 10.1038/nsb1101-968.
|
Crystal structure of the ribotoxin restrictocin and a
31-mer srd RNA inhibitor . SNAP output
|
|
1jbs
|
hydrolase-RNA |
X-ray (1.97 Å) |
Yang X, Gerczei T, Glover LT, Correll CC |
(2001) "Crystal
structures of restrictocin-inhibitor complexes with
implications for RNA recognition and base
flipping." Nat.Struct.Biol.,
8, 968-973. doi: 10.1038/nsb1101-968.
|
Crystal structure of ribotoxin restrictocin and a
29-mer srd RNA analog . SNAP output
|
|
1jbt
|
hydrolase-RNA |
X-ray (2.7 Å) |
Yang X, Gerczei T, Glover LT, Correll CC |
(2001) "Crystal
structures of restrictocin-inhibitor complexes with
implications for RNA recognition and base
flipping." Nat.Struct.Biol.,
8, 968-973. doi: 10.1038/nsb1101-968.
|
Crystal structure of ribotoxin restrictocin complexed
with a 29-mer sarcin-ricin domain RNA analog . SNAP output
|
|
1jid
|
signaling protein-RNA |
X-ray (1.8 Å) |
Wild K, Sinning I, Cusack S |
(2001) "Crystal
structure of an early protein-RNA assembly complex of
the signal recognition particle." Science,
294, 598-601. doi: 10.1126/science.1063839.
|
Human srp19 in complex with helix 6 of human srp RNA .
SNAP output
|
|
1jj2
|
ribosome |
X-ray (2.4 Å) |
Klein DJ, Schmeing TM, Moore PB, Steitz TA |
(2001) "The
kink-turn: a new RNA secondary structure motif."
EMBO J., 20, 4214-4221. doi:
10.1093/emboj/20.15.4214.
|
Fully refined crystal structure of the haloarcula
marismortui large ribosomal subunit at 2.4 angstrom
resolution . SNAP
output
|
|
1k1g
|
gene regulation-RNA |
NMR |
Liu Z, Luyten I, Bottomley MJ, Messias AC,
Houngninou-Molango S, Sprangers R, Zanier K, Kramer A,
Sattler M |
(2001) "Structural
basis for recognition of the intron branch site RNA by
splicing factor 1." Science,
294, 1098-1102. doi: 10.1126/science.1064719.
|
Structural basis for recognition of the intron branch
site RNA by splicing factor 1 . SNAP output
|
|
1k73
|
ribosome |
X-ray (3.01 Å) |
Hansen J, Moore PB, Steitz TA |
(2003) "Structures
of Five Antibiotics Bound at the Peptidyl Transferase
Center of the Large Ribosomal Subunit."
J.Mol.Biol., 330, 1061-1075.
doi: 10.1016/S0022-2836(03)00668-5.
|
Co-crystal structure of anisomycin bound to the 50s
ribosomal subunit . SNAP
output
|
|
1k8a
|
ribosome |
X-ray (3.0 Å) |
Hansen JL, Ippolito JA, Ban N, Nissen P, Moore PB,
Steitz TA |
(2002) "The
structures of four macrolide antibiotics bound to the
large ribosomal subunit." Mol.Cell,
10, 117-128. doi: 10.1016/S1097-2765(02)00570-1.
|
Co-crystal structure of carbomycin a bound to the 50s
ribosomal subunit of haloarcula marismortui . SNAP output
|
|
1k8w
|
lyase-RNA |
X-ray (1.85 Å) |
Hoang C, Ferre-D'Amare AR |
(2001) "Cocrystal
structure of a tRNA Psi55 pseudouridine synthase:
nucleotide flipping by an RNA-modifying enzyme."
Cell(Cambridge,Mass.), 107,
929-939. doi: 10.1016/S0092-8674(01)00618-3.
|
Crystal structure of the e. coli pseudouridine synthase
trub bound to a t stem-loop RNA . SNAP output
|
|
1k9m
|
ribosome |
X-ray (3.0 Å) |
Hansen JL, Ippolito JA, Ban N, Nissen P, Moore PB,
Steitz TA |
(2002) "The
structures of four macrolide antibiotics bound to the
large ribosomal subunit." Mol.Cell,
10, 117-128. doi: 10.1016/S1097-2765(02)00570-1.
|
Co-crystal structure of tylosin bound to the 50s
ribosomal subunit of haloarcula marismortui . SNAP output
|
|
1kd1
|
ribosome |
X-ray (3.0 Å) |
Hansen JL, Ippolito JA, Ban N, Nissen P, Moore PB,
Steitz TA |
(2002) "The
structures of four macrolide antibiotics bound to the
large ribosomal subunit." Mol.Cell,
10, 117-128. doi: 10.1016/S1097-2765(02)00570-1.
|
Co-crystal structure of spiramycin bound to the 50s
ribosomal subunit of haloarcula marismortui . SNAP output
|
|
1knz
|
viral protein-RNA |
X-ray (2.45 Å) |
Deo RC, Groft CM, Rajashankar KR, Burley SK |
(2002) "Recognition
of the rotavirus mRNA 3' consensus by an asymmetric
NSP3 homodimer." Cell(Cambridge,Mass.),
108, 71-81. doi: 10.1016/S0092-8674(01)00632-8.
|
Recognition of the rotavirus mrna 3' consensus by an
asymmetric nsp3 homodimer . SNAP output
|
|
1kog
|
ligase-RNA |
X-ray (3.5 Å) |
Torres-Larios A, Dock-Bregeon AC, Romby P, Rees B,
Sankaranarayanan R, Caillet J, Springer M, Ehresmann C,
Ehresmann B, Moras D |
(2002) "Structural
basis of translational control by Escherichia coli
threonyl tRNA synthetase."
Nat.Struct.Biol., 9, 343-347.
|
Crystal structure of e. coli threonyl-trna synthetase
interacting with the essential domain of its mrna
operator . SNAP
output
|
|
1kq2
|
translation-RNA |
X-ray (2.71 Å) |
Schumacher MA, Pearson RF, Moller T, Valentin-Hansen
P, Brennan RG |
(2002) "Structures
of the pleiotropic translational regulator Hfq and an
Hfq-RNA complex: a bacterial Sm-like protein."
EMBO J., 21, 3546-3556. doi:
10.1093/emboj/cdf322.
|
Crystal structure of an hfq-RNA complex . SNAP output
|
|
1kqs
|
ribosome |
X-ray (3.1 Å) |
Schmeing TM, Seila AC, Hansen JL, Freeborn B, Soukup
JK, Scaringe SA, Strobel SA, Moore PB, Steitz TA |
(2002) "A
pre-translocational intermediate in protein synthesis
observed in crystals of enzymatically active 50S
subunits." Nat.Struct.Biol.,
9, 225-230.
|
The haloarcula marismortui 50s complexed with a
pretranslocational intermediate in protein synthesis .
SNAP output
|
|
1kuq
|
ribosome |
X-ray (2.84 Å) |
Revtovich SV, Nikulin AD, Nikonov SV |
(2004) "Role of
N-terminal helix in interaction of ribosomal protein
S15 with 16S rRNA." Biochemistry Mosc.,
69, 1319-1323. doi: 10.1007/s10541-005-0076-5.
|
Crystal structure of t3c mutant s15 ribosomal protein
in complex with 16s rrna . SNAP output
|
|
1l1c
|
transcription-RNA |
NMR |
Yang Y, Declerck N, Manival X, Aymerich S, Kochoyan
M |
(2002) "Solution
structure of the LicT-RNA antitermination complex: CAT
clamping RAT." EMBO J.,
21, 1987-1997. doi: 10.1093/emboj/21.8.1987.
|
Structure of the lict bacterial antiterminator protein
in complex with its RNA target . SNAP output
|
|
1l9a
|
signaling protein-RNA |
X-ray (2.9 Å) |
Oubridge C, Kuglstatter A, Jovine L, Nagai K |
(2002) "Crystal
structure of SRP19 in complex with the S domain of SRP
RNA and its implication for the assembly of the signal
recognition particle." Mol.Cell,
9, 1251-1261. doi: 10.1016/S1097-2765(02)00530-0.
|
Crystal structure of srp19 in complex with the s domain
of signal recognition particle RNA . SNAP output
|
|
1laj
|
virus-RNA |
X-ray (3.4 Å) |
Lucas RW, Larson SB, Canady MA, McPherson A |
(2002) "The
Structure of Tomato Aspermy Virus by X-Ray
Crystallography." J.STRUCT.BIOL.,
139, 90-102. doi: 10.1016/S1047-8477(02)00561-0.
|
The structure of tomato aspermy virus by x-ray
crystallography . SNAP
output
|
|
1lng
|
signaling protein-RNA |
X-ray (2.3 Å) |
Hainzl T, Huang S, Sauer-Eriksson AE |
(2002) "Structure
of the SRP19 RNA complex and implications for signal
recognition particle assembly." Nature,
417, 767-771. doi: 10.1038/nature00768.
|
Crystal structure of the srp19-7s.s srp RNA complex of
m. jannaschii . SNAP
output
|
|
1m1k
|
ribosome |
X-ray (3.2 Å) |
Hansen JL, Ippolito JA, Ban N, Nissen P, Moore PB,
Steitz TA |
(2002) "The
structures of four macrolide antibiotics bound to the
large ribosomal subunit." Mol.Cell,
10, 117-128. doi: 10.1016/S1097-2765(02)00570-1.
|
Co-crystal structure of azithromycin bound to the 50s
ribosomal subunit of haloarcula marismortui . SNAP output
|
|
1m5k
|
translation-RNA |
X-ray (2.4 Å) |
Rupert PB, Massey AP, Sigurdsson ST, Ferre-D'Amare
AR |
(2002) "Transition
state stabilization by a catalytic RNA."
Science, 298, 1421-1424. doi:
10.1126/science.1076093.
|
Crystal structure of a hairpin ribozyme in the
catalytically-active conformation . SNAP output
|
|
1m5o
|
translation-RNA |
X-ray (2.2 Å) |
Rupert PB, Massey AP, Sigurdsson ST, Ferre-D'Amare
AR |
(2002) "Transition
state stabilization by a catalytic RNA."
Science, 298, 1421-1424. doi:
10.1126/science.1076093.
|
Transition state stabilization by a catalytic RNA .
SNAP output
|
|
1m5p
|
translation-RNA |
X-ray (2.6 Å) |
Rupert PB, Massey AP, Sigurdsson ST, Ferre-D'Amare
AR |
(2002) "Transition
state stabilization by a catalytic RNA."
Science, 298, 1421-1424. doi:
10.1126/science.1076093.
|
Transition state stabilization by a catalytic RNA .
SNAP output
|
|
1m5v
|
translation-RNA |
X-ray (2.4 Å) |
Rupert PB, Massey AP, Sigurdsson ST, Ferre-D'Amare
AR |
(2002) "Transition
state stabilization by a catalytic RNA."
Science, 298, 1421-1424. doi:
10.1126/science.1076093.
|
Transition state stabilization by a catalytic RNA .
SNAP output
|
|
1m8v
|
RNA binding protein-RNA |
X-ray (2.6 Å) |
Thore S, Mayer C, Sauter C, Weeks S, Suck D |
(2003) "Crystal
Structure of Pyrococcus abyssii Sm core and its Complex
with RNA: Common Features of RNA-binding in Archaea and
Eukarya." J.Biol.Chem.,
278, 1239-1247. doi: 10.1074/jbc.M207685200.
|
Structure of pyrococcus abyssii sm protein in complex
with a uridine heptamer . SNAP output
|
|
1m8w
|
RNA binding protein-RNA |
X-ray (2.2 Å) |
Wang X, McLachlan J, Zamore PD, Hall TMT |
(2002) "MODULAR
RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY
DOMAIN." CELL(CAMBRIDGE,MASS.),
110, 501-512. doi: 10.1016/S0092-8674(02)00873-5.
|
Crystal structure of the pumilio-homology domain from
human pumilio1 in complex with nre1-19 RNA . SNAP output
|
|
1m8x
|
RNA binding protein-RNA |
X-ray (2.2 Å) |
Wang X, McLachlan J, Zamore PD, Hall TMT |
(2002) "MODULAR
RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY
DOMAIN." CELL(CAMBRIDGE,MASS.),
110, 501-512. doi: 10.1016/S0092-8674(02)00873-5.
|
Crystal structure of the pumilio-homology domain from
human pumilio1 in complex with nre1-14 RNA . SNAP output
|
|
1m8y
|
RNA binding protein-RNA |
X-ray (2.6 Å) |
Wang X, McLachlan J, Zamore PD, Hall TMT |
(2002) "MODULAR
RECOGNITION OF RNA BY A HUMAN PUMILIO-HOMOLOGY
DOMAIN." CELL(CAMBRIDGE,MASS.),
110, 501-512. doi: 10.1016/S0092-8674(02)00873-5.
|
Crystal structure of the pumilio-homology domain from
human pumilio1 in complex with nre2-10 RNA . SNAP output
|
|
1m90
|
ribosome |
X-ray (2.8 Å) |
Hansen JL, Schmeing TM, Moore PB, Steitz TA |
(2002) "Structural
insights into peptide bond formation."
Proc.Natl.Acad.Sci.USA, 99,
11670-11675. doi: 10.1073/pnas.172404099.
|
Co-crystal structure of cca-phe-caproic acid-biotin and
sparsomycin bound to the 50s ribosomal subunit .
SNAP output
|
|
1mfq
|
signaling protein-RNA |
X-ray (3.1 Å) |
Kuglstatter A, Oubridge C, Nagai K |
(2002) "Induced
structural changes of 7SL RNA during the assembly of
human signal recognition particle."
Nat.Struct.Biol., 9, 740-744.
doi: 10.1038/nsb843.
|
Crystal structure analysis of a ternary s-domain
complex of human signal recognition particle . SNAP output
|
|
1mji
|
ribosome |
X-ray (2.5 Å) |
Perederina A, Nevskaya N, Nikonov O, Nikulin A, Dumas
P, Yao M, Tanaka I, Garber M, Gongadze G, Nikonov S |
(2002) "Detailed
analysis of RNA-protein interactions within the
bacterial ribosomal protein L5/5S rRNA complex."
RNA, 8, 1548-1557.
|
Detailed analysis of RNA-protein interactions within
the bacterial ribosomal protein l5-5s rrna complex .
SNAP output
|
|
1mms
|
ribosome |
X-ray (2.57 Å) |
Wimberly BT, Guymon R, McCutcheon JP, White SW,
Ramakrishnan V |
(1999) "A
detailed view of a ribosomal active site: the structure
of the L11-RNA complex."
Cell(Cambridge,Mass.), 97,
491-502. doi: 10.1016/S0092-8674(00)80759-X.
|
Crystal structure of the ribosomal protein l11-RNA
complex . SNAP
output
|
|
1mnb
|
viral protein-RNA |
NMR |
Puglisi JD, Chen L, Blanchard S, Frankel AD |
(1995) "Solution
structure of a bovine immunodeficiency virus Tat-TAR
peptide-RNA complex." Science,
270, 1200-1203.
|
Biv tat peptide (residues 68-81), NMR, minimized
average structure . SNAP
output
|
|
1mzp
|
ribosome |
X-ray (2.65 Å) |
Nikulin A, Eliseikina I, Tishchenko S, Nevskaya N,
Davydova N, Platonova O, Piendl W, Selmer M, Liljas A,
Drygin D, Zimmermann R, Garber M, Nikonov S |
(2003) "Structure
of the L1 protuberance in the ribosome."
Nat.Struct.Biol., 10,
104-108. doi: 10.1038/nsb886.
|
Structure of the l1 protuberance in the ribosome .
SNAP output
|
|
1n1h
|
transferase-RNA |
X-ray (2.8 Å) |
Tao Y, Farsetta DL, Nibert ML, Harrison SC |
(2002) "RNA
Synthesis in a Cage--Structural Studies of Reovirus
Polymerase [lambda] 3."
Cell(Cambridge,Mass.), 111,
733-745. doi: 10.1016/S0092-8674(02)01110-8.
|
Initiation complex of polymerase lambda3 from reovirus
. SNAP output
|
|
1n32
|
ribosome |
X-ray (3.0 Å) |
Ogle JM, Murphy IV FV, Tarry MJ, Ramakrishnan V |
(2002) "Selection
of tRNA by the Ribosome Requires a Transition from an
Open to a Closed Form."
Cell(Cambridge,Mass.), 111,
721-732. doi: 10.1016/S0092-8674(02)01086-3.
|
Structure of the thermus thermophilus 30s ribosomal
subunit bound to codon and near-cognate transfer RNA
anticodon stem-loop mismatched at the first codon
position at the a site with paromomycin . SNAP output
|
|
1n33
|
ribosome |
X-ray (3.35 Å) |
Ogle JM, Murphy IV FV, Tarry MJ, Ramakrishnan V |
(2002) "Selection
of tRNA by the Ribosome Requires a Transition from an
Open to a Closed Form."
Cell(Cambridge,Mass.), 111,
721-732. doi: 10.1016/S0092-8674(02)01086-3.
|
Structure of the thermus thermophilus 30s ribosomal
subunit bound to codon and near-cognate transfer RNA
anticodon stem-loop mismatched at the second codon
position at the a site with paromomycin . SNAP output
|
|
1n34
|
ribosome |
X-ray (3.8 Å) |
Ogle JM, Murphy IV FV, Tarry MJ, Ramakrishnan V |
(2002) "Selection
of tRNA by the Ribosome Requires a Transition from an
Open to a Closed Form."
Cell(Cambridge,Mass.), 111,
721-732. doi: 10.1016/S0092-8674(02)01086-3.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in the presence of codon and
crystallographically disordered near-cognate transfer
RNA anticodon stem-loop mismatched at the first codon
position . SNAP
output
|
|
1n35
|
transferase-RNA |
X-ray (2.5 Å) |
Tao Y, Farsetta DL, Nibert ML, Harrison SC |
(2002) "RNA
Synthesis in a Cage--Structural Studies of Reovirus
Polymerase [lambda] 3."
Cell(Cambridge,Mass.), 111,
733-745. doi: 10.1016/S0092-8674(02)01110-8.
|
Lambda3 elongation complex with four phosphodiester
bond formed . SNAP
output
|
|
1n36
|
ribosome |
X-ray (3.65 Å) |
Ogle JM, Murphy IV FV, Tarry MJ, Ramakrishnan V |
(2002) "Selection
of tRNA by the Ribosome Requires a Transition from an
Open to a Closed Form."
Cell(Cambridge,Mass.), 111,
721-732. doi: 10.1016/S0092-8674(02)01086-3.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in the presence of crystallographically
disordered codon and near-cognate transfer RNA
anticodon stem-loop mismatched at the second codon
position . SNAP
output
|
|
1n38
|
transferase-RNA |
X-ray (2.8 Å) |
Tao Y, Farsetta DL, Nibert ML, Harrison SC |
(2002) "RNA
Synthesis in a Cage--Structural Studies of Reovirus
Polymerase [lambda] 3."
Cell(Cambridge,Mass.), 111,
733-745. doi: 10.1016/S0092-8674(02)01110-8.
|
Reovirus polymerase lambda3 elongation complex with one
phosphodiester bond formed . SNAP output
|
|
1n77
|
ligase-RNA |
X-ray (2.4 Å) |
Sekine S, Nureki O, Dubois DY, Bernier S, Chenevert
R, Lapointe J, Vassylyev DG, Yokoyama S |
(2003) "ATP
binding by glutamyl-tRNA synthetase is switched to the
productive mode by tRNA binding." EMBO J.,
22, 676-688. doi: 10.1093/emboj/cdg053.
|
Crystal structure of thermus thermophilus glutamyl-trna
synthetase complexed with trna(glu) and atp. . SNAP output
|
|
1n78
|
ligase-RNA |
X-ray (2.1 Å) |
Sekine S, Nureki O, Dubois DY, Bernier S, Chenevert
R, Lapointe J, Vassylyev DG, Yokoyama S |
(2003) "ATP
binding by glutamyl-tRNA synthetase is switched to the
productive mode by tRNA binding." EMBO J.,
22, 676-688. doi: 10.1093/emboj/cdg053.
|
Crystal structure of thermus thermophilus glutamyl-trna
synthetase complexed with trna(glu) and glutamol-amp. .
SNAP output
|
|
1n8r
|
ribosome-antibiotic |
X-ray (3.0 Å) |
Hansen J, Moore PB, Steitz TA |
(2003) "Structures
of Five Antibiotics Bound at the Peptidyl Transferase
Center of the Large Ribosomal Subunit."
J.Mol.Biol., 330, 1061-1075.
doi: 10.1016/S0022-2836(03)00668-5.
|
Structure of large ribosomal subunit in complex with
virginiamycin m . SNAP
output
|
|
1nb7
|
transferase-RNA |
X-ray (2.9 Å) |
O'Farrell D, Trowbridge R, Rowlands D, Jager J |
(2003) "Substrate
complexes of hepatitis C virus RNA polymerase (HC-J4):
structural evidence for nucleotide import and de-novo
initiation." J.Mol.Biol.,
326, 1025-1035. doi: 10.1016/S0022-2836(02)01439-0.
|
Hc-j4 RNA polymerase complexed with short RNA template
strand . SNAP output
|
|
1nji
|
ribosome |
X-ray (3.0 Å) |
Hansen J, Moore PB, Steitz TA |
(2003) "Structures
of Five Antibiotics Bound at the Peptidyl Transferase
Center of the Large Ribosomal Subunit."
J.Mol.Biol., 330, 1061-1075.
doi: 10.1016/S0022-2836(03)00668-5.
|
Structure of chloramphenicol bound to the 50s ribosomal
subunit . SNAP
output
|
|
1njm
|
ribosome |
X-ray (3.6 Å) |
Bashan A, Agmon I, Zarivatch R, Schluenzen F, Harms
JM, Berisio R, Bartels H, Franceschi F, Auerbach T,
Hansen HA, Kossoy E, Kessler M, Yonath A |
(2003) "Structural
basis of the ribosomal machinery for Peptide bond
formation, translocation, and nascent chain
progression." Mol.Cell,
11, 91-102. doi: 10.1016/S1097-2765(03)00009-1.
|
The crystal structure of the 50s large ribosomal
subunit from deinococcus radiodurans complexed with a
trna acceptor stem mimic (asm) and the antibiotic
sparsomycin . SNAP
output
|
|
1njp
|
ribosome |
X-ray (3.5 Å) |
Bashan A, Agmon I, Zarivatch R, Schluenzen F, Harms
JM, Berisio R, Bartels H, Franceschi F, Auerbach T,
Hansen HA, Kossoy E, Kessler M, Yonath A |
(2003) "Structural
basis of the ribosomal machinery for Peptide bond
formation, translocation, and nascent chain
progression." Mol.Cell,
11, 91-102. doi: 10.1016/S1097-2765(03)00009-1.
|
The crystal structure of the 50s large ribosomal
subunit from deinococcus radiodurans complexed with a
trna acceptor stem mimic (asm) . SNAP output
|
|
1nyb
|
transcription-RNA |
NMR |
Cilley CD, Williamson JR |
(2003) "Structural
mimicry in the phage phi21 N peptide-boxB RNA
complex." RNA, 9,
663-676. doi: 10.1261/rna.2189203.
|
Solution structure of the bacteriophage phi21 n
peptide-boxb RNA complex . SNAP output
|
|
1o0b
|
ligase-RNA |
X-ray (2.7 Å) |
Bullock TL, Uter N, Nissan TA, Perona JJ |
(2003) "Amino
Acid Discrimination by a class I aminoacyl-tRNA
synthetase specified by negative determinants."
J.Mol.Biol., 328, 395-408.
doi: 10.1016/S0022-2836(03)00305-X.
|
Crystal structure of l-glutamine and ampcpp bound to
glutamine aminoacyl trna synthetase . SNAP output
|
|
1o0c
|
ligase-RNA |
X-ray (2.7 Å) |
Bullock TL, Uter N, Nissan TA, Perona JJ |
(2003) "Amino
Acid Discrimination by a class I aminoacyl-tRNA
synthetase specified by negative determinants."
J.Mol.Biol., 328, 395-408.
doi: 10.1016/S0022-2836(03)00305-X.
|
Crystal structure of l-glutamate and ampcpp bound to
glutamine aminoacyl trna synthetase . SNAP output
|
|
1ob2
|
hydrolase-nuclear protein |
X-ray (3.35 Å) |
Nielsen RC, Kristensen O, Kjeldgaard M, Thirup S,
Nissen P |
"Kirromycin Defines a Specific Domain Arrangement of
Elongation Factor EF-TU." |
E. coli elongation factor ef-tu complexed with the
antibiotic kirromycin, a gtp analog, and phe-trna .
SNAP output
|
|
1ob5
|
hydrolase |
X-ray (3.1 Å) |
Parmeggiani A, Krab IM, Watanabe T, Nielsen RC,
Dahlberg C, Nyborg J, Nissen P |
(2006) "Enacyloxin
Iia Pinpoints a Binding Pocket of Elongation Factor TU
for Development of Novel Antibiotics."
J.Biol.Chem., 281, 2893. doi:
10.1074/JBC.M505951200.
|
T. aquaticus elongation factor ef-tu complexed with the
antibiotic enacyloxin iia, a gtp analog, and phe-trna .
SNAP output
|
|
1oln
|
ribosome-antibiotic |
multiple methods: solution nmr, theoretical
model |
Lentzen G, Klinck R, Matassova N, Aboul-Ela F,
Murchie AIH |
(2003) "Structural
Basis for Contrasting Activities of Ribosome Binding
Thiazole Antibiotics." Chem.Biol.,
10, 769. doi: 10.1016/S1074-5521(03)00173-X.
|
Model for thiostrepton antibiotic binding to l11
substrate from 50s ribosomal RNA . SNAP output
|
|
1ooa
|
transcription-RNA |
X-ray (2.45 Å) |
Huang DB, Vu D, Cassiday LA, Zimmerman JM, Maher III
LJ, Ghosh G |
(2003) "Crystal
structure of NF-kappaB (p50)2 complexed to a
high-affinity RNA aptamer."
Proc.Natl.Acad.Sci.USA, 100,
9268-9273. doi: 10.1073/pnas.1632011100.
|
Crystal structure of nf-kb(p50)2 complexed to a
high-affinity RNA aptamer . SNAP output
|
|
1p6v
|
RNA binding protein-RNA |
X-ray (3.2 Å) |
Gutmann S, Haebel PW, Metzinger L, Sutter M, Felden
B, Ban N |
(2003) "Crystal
structure of the transfer-RNA domain of
transfer-messenger RNA in complex with SmpB."
Nature, 424, 699-703. doi:
10.1038/nature01831.
|
Crystal structure of the trna domain of
transfer-messenger RNA in complex with smpb . SNAP output
|
|
1pgl
|
virus-RNA |
X-ray (2.8 Å) |
Lin T, Cavarelli J, Johnson JE |
(2003) "Evidence
for assembly-dependent folding of protein and RNA in an
icosahedral virus." Virology,
314, 26-33. doi: 10.1016/S0042-6822(03)00457-4.
|
Bean pod mottle virus (bpmv), middle component .
SNAP output
|
|
1pvo
|
transcription-RNA |
X-ray (3.0 Å) |
Skordalakes E, Berger JM |
(2003) "Structure
of the Rho transcription terminator: mechanism of mRNA
recognition and helicase loading."
Cell(Cambridge,Mass.), 114,
135-146. doi: 10.1016/S0092-8674(03)00512-9.
|
X-ray crystal structure of rho transcription
termination factor in complex with ssrna substrate and
anppnp . SNAP output
|
|
1q2r
|
transferase-RNA |
X-ray (2.9 Å) |
Xie W, Liu X, Huang RH |
(2003) "Chemical
trapping and crystal structure of a catalytic tRNA
guanine transglycosylase covalent intermediate."
Nat.Struct.Biol., 10,
781-788. doi: 10.1038/nsb976.
|
Chemical trapping and crystal structure of a catalytic
trna guanine transglycosylase covalent intermediate .
SNAP output
|
|
1q2s
|
transferase-RNA |
X-ray (3.2 Å) |
Xie W, Liu X, Huang RH |
(2003) "Chemical
trapping and crystal structure of a catalytic tRNA
guanine transglycosylase covalent intermediate."
Nat.Struct.Biol., 10,
781-788. doi: 10.1038/nsb976.
|
Chemical trapping and crystal structure of a catalytic
trna guanine transglycosylase covalent intermediate .
SNAP output
|
|
1q7y
|
ribosome |
X-ray (3.2 Å) |
Hansen JL, Schmeing TM, Moore PB, Steitz TA |
(2002) "Structural
Insights Into Peptide Bond Formation."
Proc.Natl.Acad.Sci.USA, 99,
11670-11675. doi: 10.1073/pnas.172404099.
|
Crystal structure of ccdap-puromycin bound at the
peptidyl transferase center of the 50s ribosomal
subunit . SNAP
output
|
|
1q81
|
ribosome |
X-ray (2.95 Å) |
Hansen JL, Schmeing TM, Moore PB, Steitz TA |
(2002) "Structural
Insights into Peptide Bond Formation."
Proc.Natl.Acad.Sci.USA, 99,
11670-11675. doi: 10.1073/pnas.172404099.
|
Crystal structure of minihelix with 3' puromycin bound
to a-site of the 50s ribosomal subunit. . SNAP output
|
|
1q82
|
ribosome |
X-ray (2.98 Å) |
Hansen JL, Schmeing TM, Moore PB, Steitz TA |
(2002) "Structural
Insights Into Peptide Bond Formation."
Proc.Natl.Acad.Sci.USA, 99,
11670-11675. doi: 10.1073/pnas.172404099.
|
Crystal structure of cc-puromycin bound to the a-site
of the 50s ribosomal subunit . SNAP output
|
|
1q86
|
ribosome |
X-ray (3.0 Å) |
Hansen JL, Schmeing TM, Moore PB, Steitz TA |
(2002) "Structural
insights into peptide bond formation."
Proc.Natl.Acad.Sci.USA, 99,
11670-11675. doi: 10.1073/pnas.172404099.
|
Crystal structure of cca-phe-cap-biotin bound
simultaneously at half occupancy to both the a-site and
p-site of the the 50s ribosomal subunit. . SNAP output
|
|
1qa6
|
ribosome |
X-ray (2.8 Å) |
Conn GL, Draper DE, Lattman EE, Gittis AG |
(1999) "Crystal
structure of a conserved ribosomal protein-RNA
complex." Science, 284,
1171-1174. doi: 10.1126/science.284.5417.1171.
|
Crystal structure of a conserved ribosomal protein-RNA
complex . SNAP
output
|
|
1qf6
|
ligase-RNA |
X-ray (2.9 Å) |
Sankaranarayanan R, Dock-Bregeon AC, Romby P, Caillet
J, Springer M, Rees B, Ehresmann C, Ehresmann B, Moras
D |
(1999) "The
structure of threonyl-tRNA synthetase-tRNA(Thr) complex
enlightens its repressor activity and reveals an
essential zinc ion in the active site."
Cell(Cambridge,Mass.), 97,
371-381. doi: 10.1016/S0092-8674(00)80746-1.
|
Structure of e. coli threonyl-trna synthetase complexed
with its cognate trna . SNAP output
|
|
1qfq
|
transcription-RNA |
NMR |
Schaerpf M, Sticht H, Schweimer K, Boehm M, Hoffmann
S, Roesch P |
(2000) "Antitermination
in bacteriophage lambda. The structure of the N36
peptide-boxB RNA complex." Eur.J.Biochem.,
267, 2397-2408. doi: 10.1046/j.1432-1327.2000.01251.x.
|
Bacteriophage lambda n-protein-nutboxb-RNA complex .
SNAP output
|
|
1qrs
|
ligase-RNA |
X-ray (2.6 Å) |
Arnez JG, Steitz TA |
(1996) "Crystal
structures of three misacylating mutants of Escherichia
coli glutaminyl-tRNA synthetase complexed with
tRNA(Gln) and ATP." Biochemistry,
35, 14725-14733. doi: 10.1021/bi961532o.
|
Glutaminyl-trna synthetase mutant d235n complexed with
glutamine transfer RNA . SNAP output
|
|
1qrt
|
ligase-RNA |
X-ray (2.7 Å) |
Arnez JG, Steitz TA |
(1996) "Crystal
structures of three misacylating mutants of Escherichia
coli glutaminyl-tRNA synthetase complexed with
tRNA(Gln) and ATP." Biochemistry,
35, 14725-14733. doi: 10.1021/bi961532o.
|
Glutaminyl-trna synthetase mutant d235g complexed with
glutamine transfer RNA . SNAP output
|
|
1qru
|
ligase-RNA |
X-ray (3.0 Å) |
Arnez JG, Steitz TA |
(1996) "Crystal
structures of three misacylating mutants of Escherichia
coli glutaminyl-tRNA synthetase complexed with
tRNA(Gln) and ATP." Biochemistry,
35, 14725-14733. doi: 10.1021/bi961532o.
|
Glutaminyl-trna synthetase mutant i129t complexed with
glutamine transfer RNA . SNAP output
|
|
1qtq
|
ligase-RNA |
X-ray (2.25 Å) |
Rath VL, Silvian LF, Beijer B, Sproat BS, Steitz
TA |
(1998) "How
glutaminyl-tRNA synthetase selects glutamine."
Structure, 6, 439-449. doi:
10.1016/S0969-2126(98)00046-X.
|
Glutaminyl-trna synthetase complexed with trna and an
amino acid analog . SNAP
output
|
|
1qu2
|
ligase-RNA |
X-ray (2.2 Å) |
Silvian LF, Wang J, Steitz TA |
(1999) "Insights
into editing from an ile-tRNA synthetase structure with
tRNAile and mupirocin." Science,
285, 1074-1077. doi: 10.1126/science.285.5430.1074.
|
Insights into editing from an ile-trna synthetase
structure with trna(ile) and mupirocin . SNAP output
|
|
1qu3
|
ligase-RNA |
X-ray (2.9 Å) |
Silvian LF, Wang J, Steitz TA |
(1999) "Insights
into editing from an ile-tRNA synthetase structure with
tRNAile and mupirocin." Science,
285, 1074-1077. doi: 10.1126/science.285.5430.1074.
|
Insights into editing from an ile-trna synthetase
structure with trna(ile) and mupirocin . SNAP output
|
|
1qvf
|
ribosome |
X-ray (3.1 Å) |
Schmeing TM, Moore PB, Steitz TA |
(2003) "Structures
of deacylated tRNA mimics bound to the E site of the
large ribosomal subunit." RNA,
9, 1345-1352. doi: 10.1261/rna.5120503.
|
Structure of a deacylated trna minihelix bound to the e
site of the large ribosomal subunit of haloarcula
marismortui . SNAP
output
|
|
1qvg
|
ribosome |
X-ray (2.9 Å) |
Schmeing TM, Moore PB, Steitz TA |
(2003) "Structures
of deacylated tRNA mimics bound to the E site of the
large ribosomal subunit." RNA,
9, 1345-1352. doi: 10.1261/rna.5120503.
|
Structure of cca oligonucleotide bound to the trna
binding sites of the large ribosomal subunit of
haloarcula marismortui . SNAP output
|
|
1qzw
|
signaling protein-RNA |
X-ray (4.1 Å) |
Rosendal KR, Wild K, Montoya G, Sinning I |
(2003) "Crystal
structure of the complete core of archaeal signal
recognition particle and implications for interdomain
communication." Proc.Natl.Acad.Sci.USA,
100, 14701-14706. doi: 10.1073/pnas.2436132100.
|
Crystal structure of the complete core of archaeal srp
and implications for inter-domain communication .
SNAP output
|
|
1r3e
|
lyase-RNA |
X-ray (2.1 Å) |
Pan H, Agarwalla S, Moustakas DT, Finer-Moore J,
Stroud RM |
(2003) "Crystal
Structure of tRNA Pseudouridine Synthase TruB and Its
RNA Complex: RNA Recognition Through a Combination of
Rigid Docking and Induced Fit."
Proc.Natl.Acad.Sci.USA, 100,
12648-12653. doi: 10.1073/pnas.2135585100.
|
Crystal structure of trna pseudouridine synthase trub
and its RNA complex: RNA-protein recognition through a
combination of rigid docking and induced fit . SNAP output
|
|
1r9f
|
viral protein-RNA |
X-ray (1.85 Å) |
Ye K, Malinina L, Patel DJ |
(2003) "Recognition
of small interfering RNA by a viral suppressor of
RNA." Nature, 426,
874-878. doi: 10.1038/nature02213.
|
Crystal structure of p19 complexed with 19-bp small
interfering RNA . SNAP
output
|
|
1rc7
|
hydrolase-RNA |
X-ray (2.15 Å) |
Blaszczyk J, Gan J, Tropea JE, Court DL, Waugh DS, Ji
X |
(2004) "Noncatalytic
Assembly of Ribonuclease III with Double-Stranded
RNA." Structure, 12,
457-466. doi: 10.1016/j.str.2004.02.004.
|
Crystal structure of rnase iii mutant e110k from
aquifex aeolicus complexed with ds-RNA at 2.15 angstrom
resolution . SNAP
output
|
|
1rgo
|
RNA binding protein |
NMR |
Hudson BP, Martinez-Yamout MA, Dyson HJ, Wright
PE |
(2004) "Recognition
of the mRNA AU-rich element by the zinc finger domain
of TIS11d." NAT.STRUCT.MOL.BIOL.,
11, 257-264. doi: 10.1038/nsmb738.
|
Structural basis for recognition of the mrna class ii
au-rich element by the tandem zinc finger domain of
tis11d . SNAP output
|
|
1rkj
|
transcription-RNA |
NMR |
Johansson C, Finger LD, Trantirek L, Mueller TD, Kim
S, Laird-Offringa IA, Feigon J |
(2004) "Solution
structure of the complex formed by the two N-terminal
RNA-binding domains of nucleolin and a pre-rRNA
target." J.Mol.Biol.,
337, 799-816. doi: 10.1016/j.jmb.2004.01.056.
|
Solution structure of the complex formed by the two
n-terminal RNA-binding domains of nucleolin and a
pre-rrna target . SNAP
output
|
|
1rlg
|
structural protein-RNA |
X-ray (2.7 Å) |
Moore T, Zhang Y, Fenley MO, Li H |
(2004) "Molecular
Basis of Box C/D RNA-Protein Interactions; Cocrystal
Structure of Archaeal L7Ae and a Box C/D RNA."
STRUCTURE, 12, 807-818. doi:
10.1016/j.str.2004.02.033.
|
Molecular basis of box c-d RNA-protein interaction:
co-crystal structure of the archaeal srnp intiation
complex . SNAP
output
|
|
1rmv
|
virus-RNA |
fiber diffraction |
Wang H, Stubbs G |
(1993) "Molecular
dynamics in refinement against fiber diffraction
data." Acta Crystallogr.,Sect.A,
49, 504-513. doi: 10.1107/S0108767392011255.
|
Ribgrass mosaic virus, fiber diffraction . SNAP output
|
|
1rpu
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Vargason JM, Szittya G, Burgyan J, Hall TMT |
(2003) "Size
selective recognition of siRNA by an RNA silencing
suppressor." Cell(Cambridge,Mass.),
115, 799-811. doi: 10.1016/S0092-8674(03)00984-X.
|
Crystal structure of cirv p19 bound to sirna . SNAP output
|
|
1ry1
|
translation |
cryo-EM (12.0 Å) |
Halic M, Becker T, Pool MR, Spahn CM, Grassucci RA,
Frank J, Beckmann R |
(2004) "Structure
of the signal recognition particle interacting with the
elongation-arrested ribosome." Nature,
427, 808-814. doi: 10.1038/nature02342.
|
Structure of the signal recognition particle
interacting with the elongation-arrested ribosome .
SNAP output
|
|
1s03
|
transcription-RNA |
X-ray (2.7 Å) |
Merianos HJ, Wang J, Moore PB |
(2004) "The
structure of a ribosomal protein S8/spc operon mRNA
complex." RNA, 10,
954-964. doi: 10.1261/rna.7030704.
|
The structure of a ribosomal protein s8-spc operon mrna
complex . SNAP
output
|
|
1s72
|
ribosome |
X-ray (2.4 Å) |
Klein DJ, Moore PB, Steitz TA |
(2004) "The
Roles of Ribosomal Proteins in the Structure, Assembly
and Evolution of the Large Ribosomal Subunit."
J.Mol.Biol., 340, 141-177.
doi: 10.1016/j.jmb.2004.03.076.
|
Refined crystal structure of the haloarcula marismortui
large ribosomal subunit at 2.4 angstrom resolution .
SNAP output
|
|
1sds
|
protein-RNA complex |
X-ray (1.8 Å) |
Hamma T, Ferre-D'Amare A |
(2004) "Structure
of Protein L7Ae Bound to a K-Turn Derived from an
Archaeal Box H/ACA sRNA at 1.8 A Resolution."
STRUCTURE, 12, 893-903. doi:
10.1016/j.str.2004.03.015.
|
Structure of protein l7ae bound to a k-turn derived
from an archaeal box h-aca srna . SNAP output
|
|
1ser
|
ligase-RNA |
X-ray (2.9 Å) |
Biou V, Yaremchuk A, Tukalo M, Cusack S |
(1994) "The 2.9 A
crystal structure of T. thermophilus seryl-tRNA
synthetase complexed with tRNA(Ser)."
Science, 263, 1404-1410.
|
The 2.9 angstroms crystal structure of t. thermophilus
seryl-trna synthetase complexed with trna ser .
SNAP output
|
|
1si3
|
gene regulation-RNA |
X-ray (2.6 Å) |
Ma JB, Ye K, Patel DJ |
(2004) "Structural
basis for overhang-specific small interfering RNA
recognition by the PAZ domain." Nature,
429, 318-322. doi: 10.1038/nature02519.
|
Crystal structure of the paz domain of human eif2c1 in
complex with a 9-mer sirna-like duplex . SNAP output
|
|
1sj3
|
translation-RNA |
X-ray (2.2 Å) |
Ke A, Zhou K, Ding F, Cate JH, Doudna JA |
(2004) "A
Conformational Switch controls hepatitis delta virus
ribozyme catalysis." Nature,
429, 201-205. doi: 10.1038/nature02522.
|
Hepatitis delta virus gemonic ribozyme precursor, with
mg2+ bound . SNAP
output
|
|
1sj4
|
translation-RNA |
X-ray (2.7 Å) |
Ke A, Zhou K, Ding F, Cate JH, Doudna JA |
(2004) "A
Conformational Switch controls hepatitis delta virus
ribozyme catalysis." Nature,
429, 201-205. doi: 10.1038/nature02522.
|
Crystal structure of a c75u mutant hepatitis delta
virus ribozyme precursor, in cu2+ solution . SNAP output
|
|
1sjf
|
translation-RNA |
X-ray (2.75 Å) |
Ke A, Zhou K, Ding F, Cate JH, Doudna JA |
(2004) "A
conformational switch controls hepatitis delta virus
ribozyme catalysis." Nature,
429, 201-205. doi: 10.1038/nature02522.
|
Crystal structure of the hepatitis delta virus gemonic
ribozyme precursor, with c75u mutaion, in cobalt
hexammine solution . SNAP output
|
|
1sm1
|
ribosome-antibiotic |
X-ray (3.42 Å) |
Harms JM, Schlunzen F, Fucini P, Bartels H, Yonath
A |
(2004) "Alterations
at the Peptidyl Transferase Centre of the Ribosome
Induced by the Synergistic Action of the Streptogramins
Dalfopristin and Quinupristin." Bmc Biol.,
2, 4. doi: 10.1186/1741-7007-2-4.
|
Complex of the large ribosomal subunit from deinococcus
radiodurans with quinupristin and dalfopristin .
SNAP output
|
|
1sz1
|
transferase-RNA |
X-ray (6.21 Å) |
Xiong Y, Steitz TA |
(2004) "Mechanism
of transfer RNA maturation by CCA-adding enzyme without
using an oligonucleotide template."
Nature, 430, 640-645. doi:
10.1038/nature02711.
|
Mechanism of cca-adding enzymes specificity revealed by
crystal structures of ternary complexes . SNAP output
|
|
1t0k
|
ribosome |
X-ray (3.24 Å) |
Chao JA, Williamson JR |
(2004) "Joint
X-Ray and NMR Refinement of the Yeast L30e-mRNA
Complex." Structure, 12,
1165-1176. doi: 10.1016/j.str.2004.04.023.
|
Joint x-ray and NMR refinement of yeast l30e-mrna
complex . SNAP
output
|
|
1t2r
|
nucleic acid binding protein-RNA |
NMR |
Lingel A, Simon B, Izaurralde E, Sattler M |
(2004) "Nucleic
acid 3'-end recognition by the Argonaute2 PAZ
domain." Nat.Struct.Mol.Biol.,
11, 576-577. doi: 10.1038/nsmb777.
|
Structural basis for 3' end recognition of nucleic
acids by the drosophila argonaute 2 paz domain .
SNAP output
|
|
1t4l
|
RNA binding protein-RNA |
NMR |
Wu H, Henras A, Chanfreau G, Feigon J |
(2004) "Structural
basis for recognition of the AGNN tetraloop RNA fold by
the double-stranded RNA-binding domain of Rnt1p RNase
III." Proc.Natl.Acad.Sci.USA,
101, 8307-8312. doi: 10.1073/pnas.0402627101.
|
Solution structure of double-stranded RNA binding
domain of s. cerevisiae rnase iii (rnt1p) in complex
with the 5' terminal RNA hairpin of snr47 precursor .
SNAP output
|
|
1tfw
|
transferase-RNA |
X-ray (2.2 Å) |
Xiong Y, Steitz TA |
(2004) "Mechanism
of transfer RNA maturation by CCA-adding enzyme without
using an oligonucleotide template."
Nature, 430, 640-645. doi:
10.1038/nature02711.
|
How cca is added to the 3' end of immature trna without
the use of an oligonucleotide template . SNAP output
|
|
1tfy
|
transferase-RNA |
X-ray (3.2 Å) |
Xiong Y, Steitz TA |
(2004) "Mechanism
of transfer RNA maturation by CCA-adding enzyme without
using an oligonucleotide template."
Nature, 430, 640-645. doi:
10.1038/nature02711.
|
How cca is added to the 3' end of immature trna without
the use of an oligonucleotide template . SNAP output
|
|
1ttt
|
complex (elongation factor-trna) |
X-ray (2.7 Å) |
Nissen P, Kjeldgaard M, Thirup S, Polekhina G,
Reshetnikova L, Clark BF, Nyborg J |
(1995) "Crystal
structure of the ternary complex of Phe-tRNAPhe, EF-Tu,
and a GTP analog." Science,
270, 1464-1472.
|
Phe-trna, elongation factor ef-tu:gdpnp ternary complex
. SNAP output
|
|
1u0b
|
ligase-RNA |
X-ray (2.3 Å) |
Hauenstein S, Zhang CM, Hou YM, Perona JJ |
(2004) "Shape-selective
RNA recognition by cysteinyl-tRNA synthetase."
Nat.Struct.Mol.Biol., 11,
1134-1141. doi: 10.1038/nsmb849.
|
Crystal structure of cysteinyl-trna synthetase binary
complex with trnacys . SNAP output
|
|
1u63
|
transcription-RNA |
X-ray (3.4 Å) |
Nevskaya N, Tishchenko S, Gabdoulkhakov A, Nikonova
E, Nikonov O, Nikulin A, Platonova O, Garber M, Nikonov
S, Piendl W |
(2005) "Ribosomal
protein L1 recognizes the same specific structural
motif in its target sites on the autoregulatory mRNA
and 23S rRNA." Nucleic Acids Res.,
33, 478-485. doi: 10.1093/nar/gki194.
|
The structure of a ribosomal protein l1-mrna complex .
SNAP output
|
|
1u6b
|
structural protein-RNA |
X-ray (3.1 Å) |
Adams PL, Stahley MR, Kosek AB, Wang J, Strobel
SA |
(2004) "Crystal
Structure of a Self-Splicing Group I Intron with Both
Exons." Nature, 430,
45-50. doi: 10.1038/nature02642.
|
Crystal structure of a self-splicing group i intron
with both exons . SNAP
output
|
|
1u6p
|
viral protein-RNA |
NMR |
D'Souza V, Summers MF |
(2004) "Structural
basis for packaging the dimeric genome of Moloney
murine leukaemia virus." Nature,
431, 586-590. doi: 10.1038/nature02944.
|
NMR structure of the mlv encapsidation signal bound to
the nucleocapsid protein . SNAP output
|
|
1ull
|
viral protein-RNA |
NMR |
Ye X, Gorin A, Ellington AD, Patel DJ |
(1996) "Deep
penetration of an alpha-helix into a widened RNA major
groove in the HIV-1 rev peptide-RNA aptamer
complex." Nat.Struct.Biol.,
3, 1026-1033. doi: 10.1038/nsb1296-1026.
|
RNA aptamer complexed with hiv-1 rev peptide, NMR, 7
structures . SNAP
output
|
|
1un6
|
RNA-binding protein-RNA |
X-ray (3.1 Å) |
Lu D, Searles MA, Klug A |
(2003) "Crystal
Structure of a Zinc-Finger-RNA Complex Reveals Two
Modes of Molecular Recognition." Nature,
426, 96. doi: 10.1038/NATURE02088.
|
The crystal structure of a zinc finger - RNA complex
reveals two modes of molecular recognition . SNAP output
|
|
1uon
|
polymerase |
cryo-EM (7.6 Å) |
Zhang X, Walker SB, Chipman PR, Nibert ML, Baker
TS |
(2003) "Reovirus
Polymerase Lambda3 Localized by Cryo-Electron
Microscopy of Virions at a Resolution of 7.6 A."
Nat.Struct.Biol., 10, 1011.
doi: 10.1038/NSB1009.
|
Reovirus polymerase lambda-3 localized by electron
cryomicroscopy of virions at 7.6-a resolution .
SNAP output
|
|
1utd
|
RNA binding protein |
X-ray (2.1 Å) |
Hopcroft NH, Manfredo A, Wendt AL, Brzozowski AM,
Gollnick P, Antson AA |
(2004) "The
Interaction of RNA with Trap: The Role of Triplet
Repeats and Separating Spacer Nucleotides."
J.Mol.Biol., 338, 43. doi:
10.1016/J.JMB.2004.02.038.
|
The structure of the trp RNA-binding attenuation
protein (trap) bound to a 63-nucleotide RNA molecule
containing gaguuu repeats . SNAP output
|
|
1uvi
|
polymerase |
X-ray (2.15 Å) |
Salgado PS, Makeyev EV, Butcher SJ, Bamford DH,
Stuart DI, Grimes JM |
(2004) "The
structural basis for RNA specificity and Ca2+
inhibition of an RNA-dependent RNA polymerase."
Structure, 12, 307-316. doi:
10.1016/j.str.2004.01.012.
|
The structural basis for RNA specificity and ca2
inhibition of an RNA-dependent RNA polymerase phi6p2
with 6nt RNA . SNAP
output
|
|
1uvj
|
polymerase |
X-ray (1.9 Å) |
Salgado PS, Makeyev EV, Butcher SJ, Bamford DH,
Stuart DI, Grimes JM |
(2004) "The
structural basis for RNA specificity and Ca2+
inhibition of an RNA-dependent RNA polymerase."
Structure, 12, 307-316. doi:
10.1016/j.str.2004.01.012.
|
The structural basis for RNA specificity and ca2
inhibition of an RNA-dependent RNA polymerase phi6p2
with 7nt RNA . SNAP
output
|
|
1uvl
|
transferase |
X-ray (2.0 Å) |
Salgado PS, Makeyev EV, Butcher SJ, Bamford DH,
Stuart DI, Grimes JM |
(2004) "The
structural basis for RNA specificity and Ca2+
inhibition of an RNA-dependent RNA polymerase."
Structure, 12, 307-316. doi:
10.1016/j.str.2004.01.012.
|
The structural basis for RNA specificity and ca2
inhibition of an RNA-dependent RNA polymerase phi6p2
with 5nt RNA. conformation b . SNAP output
|
|
1uvm
|
transferase |
X-ray (2.0 Å) |
Salgado PS, Makeyev EV, Butcher SJ, Bamford DH,
Stuart DI, Grimes JM |
(2004) "The
structural basis for RNA specificity and Ca2+
inhibition of an RNA-dependent RNA polymerase."
Structure, 12, 307-316. doi:
10.1016/j.str.2004.01.012.
|
The structural basis for RNA specificity and ca2
inhibition of an RNA-dependent RNA polymerase phi6p2
with 5nt RNA conformation a . SNAP output
|
|
1uvn
|
polymerase |
X-ray (3.0 Å) |
Salgado PS, Makeyev EV, Butcher SJ, Bamford DH,
Stuart DI, Grimes JM |
(2004) "The
structural basis for RNA specificity and Ca2+
inhibition of an RNA-dependent RNA polymerase."
Structure, 12, 307-316. doi:
10.1016/j.str.2004.01.012.
|
The structural basis for RNA specificity and ca2
inhibition of an RNA-dependent RNA polymerase phi6p2
ca2+ inhibition complex . SNAP output
|
|
1vbx
|
translation-RNA |
X-ray (2.7 Å) |
Ke A, Zhou K, Ding F, Cate JHD, Doudna JA |
(2004) "A
Conformational Switch controls hepatitis delta virus
ribozyme catalysis." NATURE,
429, 201-205. doi: 10.1038/nature02522.
|
Crystal structure of the hepatitis delta virus gemonic
ribozyme precursor, with c75u mutaion, in edta solution
. SNAP output
|
|
1vby
|
translation-RNA |
X-ray (2.9 Å) |
Ke A, Zhou K, Ding F, Cate JHD, Doudna JA |
(2004) "A
Conformational Switch controls hepatitis delta virus
ribozyme catalysis." NATURE,
429, 201-205. doi: 10.1038/nature02522.
|
Crystal structure of the hepatitis delta virus gemonic
ribozyme precursor, with c75u mutaion, and mn2+ bound .
SNAP output
|
|
1vbz
|
translation-RNA |
X-ray (2.8 Å) |
Ke A, Zhou K, Ding F, Cate JHD, Doudna JA |
(2004) "A
Conformational Switch controls hepatitis delta virus
ribozyme catalysis." NATURE,
429, 201-205. doi: 10.1038/nature02522.
|
Crystal structure of the hepatitis delta virus gemonic
ribozyme precursor, with c75u mutaion, in ba2+ solution
. SNAP output
|
|
1vc0
|
translation-RNA |
X-ray (2.5 Å) |
Ke A, Zhou K, Ding F, Cate JHD, Doudna JA |
(2004) "A
Conformational Switch controls hepatitis delta virus
ribozyme catalysis." NATURE,
429, 201-205. doi: 10.1038/nature02522.
|
Crystal structure of the hepatitis delta virus gemonic
ribozyme precursor, with c75u mutaion, in imidazole and
sr2+ solution . SNAP
output
|
|
1vc5
|
translation-RNA |
X-ray (3.4 Å) |
Ke A, Zhou K, Ding F, Cate JHD, Doudna JA |
(2004) "A
Conformational Switch controls hepatitis delta virus
ribozyme catalysis." NATURE,
429, 201-205. doi: 10.1038/nature02522.
|
Crystal structure of the wild type hepatitis delta
virus gemonic ribozyme precursor, in edta solution .
SNAP output
|
|
1vc6
|
translation-RNA |
X-ray (2.8 Å) |
Ke A, Zhou K, Ding F, Cate JHD, Doudna JA |
(2004) "A
Conformational Switch controls hepatitis delta virus
ribozyme catalysis." NATURE,
429, 201-205. doi: 10.1038/nature02522.
|
Crystal structure of the hepatitis delta virus gemonic
ribozyme product with c75u mutaion, cleaved in
imidazole and mg2+ solutions . SNAP output
|
|
1vfg
|
transferase-RNA |
X-ray (2.8 Å) |
Tomita K, Fukai S, Ishitani R, Ueda T, Takeuchi N,
Vassylyev DG, Nureki O |
(2004) "Structural
basis for template-independent RNA polymerization."
Nature, 430, 700-704. doi:
10.1038/nature02712.
|
Crystal structure of trna nucleotidyltransferase
complexed with a primer trna and an incoming atp analog
. SNAP output
|
|
1vq4
|
ribosome |
X-ray (2.7 Å) |
Schmeing TM, Huang KS, Kitchen DE, Strobel SA, Steitz
TA |
(2005) "Structural
Insights into the Roles of Water and the 2' Hydroxyl of
the P Site tRNA in the Peptidyl Transferase
Reaction." Mol.Cell, 20,
437-448. doi: 10.1016/j.molcel.2005.09.006.
|
The structure of the transition state analogue "daa"
bound to the large ribosomal subunit of haloarcula
marismortui . SNAP
output
|
|
1vq6
|
ribosome |
X-ray (2.7 Å) |
Schmeing TM, Huang KS, Strobel SA, Steitz TA |
(2005) "An
induced-fit mechanism to promote peptide bond formation
and exclude hydrolysis of peptidyl-tRNA."
Nature, 438, 520-524. doi:
10.1038/nature04152.
|
The structure of c-hpmn and cca-phe-cap-bio bound to
the large ribosomal subunit of haloarcula marismortui .
SNAP output
|
|
1vq7
|
ribosome |
X-ray (2.5 Å) |
Schmeing TM, Huang KS, Strobel SA, Steitz TA |
(2005) "An
induced-fit mechanism to promote peptide bond formation
and exclude hydrolysis of peptidyl-tRNA."
Nature, 438, 520-524. doi:
10.1038/nature04152.
|
The structure of the transition state analogue "dca"
bound to the large ribosomal subunit of haloarcula
marismortui . SNAP
output
|
|
1vq8
|
ribosome |
X-ray (2.2 Å) |
Schmeing TM, Huang KS, Kitchen DE, Strobel SA, Steitz
TA |
(2005) "Structural
Insights into the Roles of Water and the 2' Hydroxyl of
the P Site tRNA in the Peptidyl Transferase
Reaction." Mol.Cell, 20,
437-448. doi: 10.1016/j.molcel.2005.09.006.
|
The structure of ccda-phe-cap-bio and the antibiotic
sparsomycin bound to the large ribosomal subunit of
haloarcula marismortui . SNAP output
|
|
1vq9
|
ribosome |
X-ray (2.4 Å) |
Schmeing TM, Huang KS, Kitchen DE, Strobel SA, Steitz
TA |
(2005) "Structural
Insights into the Roles of Water and the 2' Hydroxyl of
the P Site tRNA in the Peptidyl Transferase
Reaction." Mol.Cell, 20,
437-448. doi: 10.1016/j.molcel.2005.09.006.
|
The structure of cca-phe-cap-bio and the antibiotic
sparsomycin bound to the large ribosomal subunit of
haloarcula marismortui . SNAP output
|
|
1vqk
|
ribosome |
X-ray (2.3 Å) |
Schmeing TM, Huang KS, Kitchen DE, Strobel SA, Steitz
TA |
(2005) "Structural
Insights into the Roles of Water and the 2' Hydroxyl of
the P Site tRNA in the Peptidyl Transferase
Reaction." Mol.Cell, 20,
437-448. doi: 10.1016/j.molcel.2005.09.006.
|
The structure of ccda-phe-cap-bio bound to the a site
of the ribosomal subunit of haloarcula marismortui .
SNAP output
|
|
1vql
|
ribosome |
X-ray (2.3 Å) |
Schmeing TM, Huang KS, Kitchen DE, Strobel SA, Steitz
TA |
(2005) "Structural
Insights into the Roles of Water and the 2' Hydroxyl of
the P Site tRNA in the Peptidyl Transferase
Reaction." Mol.Cell, 20,
437-448. doi: 10.1016/j.molcel.2005.09.006.
|
The structure of the transition state analogue "dcsn"
bound to the large ribosomal subunit of haloarcula
marismortui . SNAP
output
|
|
1vqm
|
ribosome |
X-ray (2.3 Å) |
Schmeing TM, Huang KS, Kitchen DE, Strobel SA, Steitz
TA |
(2005) "Structural
Insights into the Roles of Water and the 2' Hydroxyl of
the P Site tRNA in the Peptidyl Transferase
Reaction." Mol.Cell, 20,
437-448. doi: 10.1016/j.molcel.2005.09.006.
|
The structure of the transition state analogue "dan"
bound to the large ribosomal subunit of haloarcula
marismortui . SNAP
output
|
|
1vqn
|
ribosome |
X-ray (2.4 Å) |
Schmeing TM, Huang KS, Strobel SA, Steitz TA |
(2005) "An
induced-fit mechanism to promote peptide bond formation
and exclude hydrolysis of peptidyl-tRNA."
Nature, 438, 520-524. doi:
10.1038/nature04152.
|
The structure of cc-hpmn and cca-phe-cap-bio bound to
the large ribosomal subunit of haloarcula marismortui .
SNAP output
|
|
1vqo
|
ribosome |
X-ray (2.2 Å) |
Schmeing TM, Huang KS, Kitchen DE, Strobel SA, Steitz
TA |
(2005) "Structural
Insights into the Roles of Water and the 2' Hydroxyl of
the P Site tRNA in the Peptidyl Transferase
Reaction." Mol.Cell, 20,
437-448. doi: 10.1016/j.molcel.2005.09.006.
|
The structure of ccpmn bound to the large ribosomal
subunit haloarcula marismortui . SNAP output
|
|
1vtm
|
virus-RNA |
fiber diffraction |
Pattanayek R, Stubbs G |
(1992) "Structure
of the U2 strain of tobacco mosaic virus refined at 3.5
A resolution using X-ray fiber diffraction."
J.Mol.Biol., 228, 516-528.
doi: 10.1016/0022-2836(92)90839-C.
|
Structure of the u2 strain of tobacco mosaic virus
refined at 3.5 angstroms resolution using x-ray fiber
diffraction . SNAP
output
|
|
1vvj
|
ribosome |
X-ray (3.44 Å) |
Maehigashi T, Dunkle JA, Miles SJ, Dunham CM |
(2014) "Structural
insights into +1 frameshifting promoted by expanded or
modification-deficient anticodon stem loops."
Proc.Natl.Acad.Sci.USA, 111,
12740-12745. doi: 10.1073/pnas.1409436111.
|
Crystal structure of frameshift suppressor trna sufa6
bound to codon ccc-g on the ribosome . SNAP output
|
|
1vy4
|
ribosome |
X-ray (2.6 Å) |
Polikanov YS, Steitz TA, Innis CA |
(2014) "A proton
wire to couple aminoacyl-tRNA accommodation and
peptide-bond formation on the ribosome."
Nat.Struct.Mol.Biol., 21,
787-793. doi: 10.1038/nsmb.2871.
|
Crystal structure of the thermus thermophilus 70s
ribosome in the pre-attack state of peptide bond
formation containing acylated trna-substrates in the a
and p sites. . SNAP
output
|
|
1vy5
|
ribosome |
X-ray (2.55 Å) |
Polikanov YS, Steitz TA, Innis CA |
(2014) "A proton
wire to couple aminoacyl-tRNA accommodation and
peptide-bond formation on the ribosome."
Nat.Struct.Mol.Biol., 21,
787-793. doi: 10.1038/nsmb.2871.
|
Crystal structure of the thermus thermophilus 70s
ribosome in the post-catalysis state of peptide bond
formation containing dipeptydil-trna in the a site and
deacylated trna in the p site. . SNAP output
|
|
1vy6
|
ribosome |
X-ray (2.9 Å) |
Polikanov YS, Steitz TA, Innis CA |
(2014) "A proton
wire to couple aminoacyl-tRNA accommodation and
peptide-bond formation on the ribosome."
Nat.Struct.Mol.Biol., 21,
787-793. doi: 10.1038/nsmb.2871.
|
Crystal structure of the thermus thermophilus 70s
ribosome in the pre-attack state of peptide bond
formation containing short substrate-mimic
cytidine-puromycin in the a site and acylated trna in
the p site. . SNAP
output
|
|
1vy7
|
ribosome |
X-ray (2.8 Å) |
Polikanov YS, Steitz TA, Innis CA |
(2014) "A proton
wire to couple aminoacyl-tRNA accommodation and
peptide-bond formation on the ribosome."
Nat.Struct.Mol.Biol., 21,
787-793. doi: 10.1038/nsmb.2871.
|
Crystal structure of the thermus thermophilus 70s
ribosome in the pre-attack state of peptide bond
formation containing short substrate-mimic
cytidine-cytidine-puromycin in the a site and acylated
trna in the p site. . SNAP output
|
|
1w2b
|
ribosome |
X-ray (3.5 Å) |
Ferbitz L, Maier T, Patzelt H, Bukau B, Deuerling E,
Ban N |
(2004) "Trigger
Factor in Complex with the Ribosome Forms a Molecular
Cradle for Nascent Proteins." Nature,
431, 590. doi: 10.1038/NATURE02899.
|
Trigger factor ribosome binding domain in complex with
50s . SNAP output
|
|
1wmq
|
transcription-RNA |
X-ray (1.6 Å) |
Kumarevel T, Mizuno H, Kumar PK |
(2005) "Structural
basis of HutP-mediated anti-termination and roles of
the Mg2+ ion and L-histidine ligand."
Nature, 434, 183-191. doi:
10.1038/nature03355.
|
Structure of the hutp antitermination complex bound to
a single stranded region of hut mrna . SNAP output
|
|
1wne
|
transferase-RNA |
X-ray (3.0 Å) |
Ferrer-Orta C, Arias A, Perez-Luque R, Escarmis C,
Domingo E, Verdaguer N |
(2004) "Structure
of Foot-and-Mouth Disease Virus RNA-dependent RNA
Polymerase and Its Complex with a Template-Primer
RNA." J.Biol.Chem., 279,
47212-47221. doi: 10.1074/jbc.M405465200.
|
Foot and mouth disease virus RNA-dependent RNA
polymerase in complex with a template-primer RNA .
SNAP output
|
|
1wpu
|
transcription-RNA |
X-ray (1.48 Å) |
Kumarevel TS, Mizuno H, Kumar PKR |
"Structural basis for the HutP antitermination
Complex:Role of divalent metal ions in allosteric
activation." |
Crystal structure of the hutp antitermination complex
bound to a single stranded region of hut mrna .
SNAP output
|
|
1wrq
|
transcription-RNA |
X-ray (2.2 Å) |
Kumarevel T, Mizuno H, Kumar PKR |
"Crystal Structure of the HutP-antitermination
complex." |
Crystal structure of hutp-antitermination complex .
SNAP output
|
|
1wsu
|
translation-RNA |
X-ray (2.3 Å) |
Yoshizawa S, Rasubala L, Ose T, Kohda D, Fourmy D,
Maenaka K |
(2005) "Structural
basis for mRNA recognition by elongation factor
SelB." Nat.Struct.Mol.Biol.,
12, 198-203. doi: 10.1038/nsmb890.
|
C-terminal domain of elongation factor selb complexed
with secis RNA . SNAP
output
|
|
1wwd
|
viral protein-RNA |
NMR |
Dey A, York D, Smalls-Mantey A, Summers MF |
(2005) "Composition
and sequence-dependent binding of RNA to the
nucleocapsid protein of Moloney murine leukemia
virus(,)." Biochemistry,
44, 3735-3744. doi: 10.1021/bi047639q.
|
NMR structure determined for mlv nc complex with RNA
sequence aacagu . SNAP
output
|
|
1wwe
|
viral protein-RNA |
NMR |
Dey A, York D, Smalls-Mantey A, Summers MF |
(2005) "Composition
and sequence-dependent binding of RNA to the
nucleocapsid protein of Moloney murine leukemia
virus(,)." Biochemistry,
44, 3735-3744. doi: 10.1021/bi047639q.
|
NMR structure determined for mlv nc complex with RNA
sequence uuuugcu . SNAP
output
|
|
1wwf
|
viral protein-RNA |
NMR |
Dey A, York D, Smalls-Mantey A, Summers MF |
(2005) "Composition
and sequence-dependent binding of RNA to the
nucleocapsid protein of Moloney murine leukemia
virus(,)." Biochemistry,
44, 3735-3744. doi: 10.1021/bi047639q.
|
NMR structure determined for mlv nc complex with RNA
sequence ccuccgu . SNAP
output
|
|
1wwg
|
viral protein-RNA |
NMR |
Dey A, York D, Smalls-Mantey A, Summers MF |
(2005) "Composition
and sequence-dependent binding of RNA to the
nucleocapsid protein of Moloney murine leukemia
virus(,)." Biochemistry,
44, 3735-3744. doi: 10.1021/bi047639q.
|
NMR structure determined for mlv nc complex with RNA
sequence uaucug . SNAP
output
|
|
1wz2
|
ligase-RNA |
X-ray (3.21 Å) |
Fukunaga R, Yokoyama S |
"The crystal structure of Leucyl-tRNA synthetase and
tRNA(leucine) complex." |
The crystal structure of leucyl-trna synthetase and
trna(leucine) complex . SNAP output
|
|
1xmo
|
ribosome |
X-ray (3.25 Å) |
Murphy FV, Ramakrishnan V, Malkiewicz A, Agris
PF |
(2004) "The role
of modifications in codon discrimination by
tRNA(Lys)(UUU)." Nat.Struct.Mol.Biol.,
11, 1186-1191. doi: 10.1038/nsmb861.
|
Crystal structure of mnm5u34t6a37-trnalysuuu complexed
with aag-mrna in the decoding center . SNAP output
|
|
1xmq
|
ribosome |
X-ray (3.0 Å) |
Murphy FV, Ramakrishnan V, Malkiewicz A, Agris
PF |
(2004) "The role
of modifications in codon discrimination by
tRNA(Lys)(UUU)." Nat.Struct.Mol.Biol.,
11, 1186-1191. doi: 10.1038/nsmb861.
|
Crystal structure of t6a37-asllysuuu aaa-mrna bound to
the decoding center . SNAP output
|
|
1xnq
|
ribosome |
X-ray (3.05 Å) |
Murphy FV, Ramakrishnan V |
(2004) "Structure
of a purine-purine wobble base pair in the decoding
center of the ribosome."
Nat.Struct.Mol.Biol., 11,
1251-1252. doi: 10.1038/nsmb866.
|
Structure of an inosine-adenine wobble base pair
complex in the context of the decoding center .
SNAP output
|
|
1xnr
|
ribosome |
X-ray (3.1 Å) |
Murphy FV, Ramakrishnan V |
(2004) "Structure
of a purine-purine wobble base pair in the decoding
center of the ribosome."
Nat.Struct.Mol.Biol., 11,
1251-1252. doi: 10.1038/nsmb866.
|
Crystal structure of an inosine-cytosine wobble base
pair in the context of the decoding center . SNAP output
|
|
1xok
|
viral protein-RNA |
X-ray (3.0 Å) |
Guogas LM, Filman DJ, Hogle JM, Gehrke L |
(2004) "Cofolding
organizes alfalfa mosaic virus RNA and coat protein for
replication." Science,
306, 2108-2111. doi: 10.1126/science.1103399.
|
Crystal structure of alfalfa mosaic virus RNA 3'utr in
complex with coat protein n terminal peptide . SNAP output
|
|
1xpo
|
transcription-RNA |
X-ray (3.15 Å) |
Skordalakes E, Brogan AP, Park BS, Kohn H, Berger
JM |
(2005) "Structural
mechanism of inhibition of the rho transcription
termination factor by the antibiotic bicyclomycin."
Structure, 13, 99-109. doi:
10.1016/j.str.2004.10.013.
|
Structural mechanism of inhibition of the rho
transcription termination factor by the antibiotic
bicyclomycin . SNAP
output
|
|
1xpr
|
transcription-RNA |
X-ray (3.15 Å) |
Skordalakes E, Brogan AP, Park BS, Kohn H, Berger
JM |
(2005) "Structural
mechanism of inhibition of the rho transcription
termination factor by the antibiotic bicyclomycin."
Structure, 13, 99-109. doi:
10.1016/j.str.2004.10.013.
|
Structural mechanism of inhibition of the rho
transcription termination factor by the antibiotic
5a-formylbicyclomycin (fb) . SNAP output
|
|
1xpu
|
transcription-RNA |
X-ray (3.05 Å) |
Skordalakes E, Brogan AP, Park BS, Kohn H, Berger
JM |
(2005) "Structural
mechanism of inhibition of the rho transcription
termination factor by the antibiotic bicyclomycin."
Structure, 13, 99-109. doi:
10.1016/j.str.2004.10.013.
|
Structural mechanism of inhibition of the rho
transcription termination factor by the antibiotic
5a-(3-formylphenylsulfanyl)-dihydrobicyclomycin (fpdb)
. SNAP output
|
|
1y39
|
structural protein-RNA |
X-ray (2.8 Å) |
Dunstan MS, Guhathakurta D, Draper DE, Conn GL |
(2005) "Coevolution
of Protein and RNA Structures within a Highly Conserved
Ribosomal Domain." Chem.Biol.,
12, 201-206. doi: 10.1016/j.chembiol.2004.11.019.
|
Co-evolution of protein and RNA structures within a
highly conserved ribosomal domain . SNAP output
|
|
1y69
|
ribosome |
X-ray (3.33 Å) |
Wilson DN, Schluenzen F, Harms JM, Yoshida T, Ohkubo
T, Albrecht R, Buerger J, Kobayashi Y, Fucini P |
(2005) "X-ray
crystallography on ribosome recycling: mechanism of
binding and action of RRF on the 50S ribosomal
subunit." EMBO J., 24,
251-260. doi: 10.1038/sj.emboj.7600525.
|
Rrf domain i in complex with the 50s ribosomal subunit
from deinococcus radiodurans . SNAP output
|
|
1yhq
|
ribosome |
X-ray (2.4 Å) |
Tu D, Blaha G, Moore PB, Steitz TA |
(2005) "Structures
of MLSBK antibiotics bound to mutated large ribosomal
subunits provide a structural explanation for
resistance." Cell(Cambridge,Mass.),
121, 257-270. doi: 10.1016/j.cell.2005.02.005.
|
Crystal structure of azithromycin bound to the g2099a
mutant 50s ribosomal subunit of haloarcula marismortui
. SNAP output
|
|
1yi2
|
ribosome |
X-ray (2.65 Å) |
Tu D, Blaha G, Moore PB, Steitz TA |
(2005) "Structures
of MLSBK antibiotics bound to mutated large ribosomal
subunits provide a structural explanation for
resistance." Cell(Cambridge,Mass.),
121, 257-270. doi: 10.1016/j.cell.2005.02.005.
|
Crystal structure of erythromycin bound to the g2099a
mutant 50s ribosomal subunit of haloarcula marismortui
. SNAP output
|
|
1yij
|
ribosome |
X-ray (2.6 Å) |
Tu D, Blaha G, Moore PB, Steitz TA |
(2005) "Structures
of MLSBK antibiotics bound to mutated large ribosomal
subunits provide a structural explanation for
resistance." Cell(Cambridge,Mass.),
121, 257-270. doi: 10.1016/j.cell.2005.02.005.
|
Crystal structure of telithromycin bound to the g2099a
mutant 50s ribosomal subunit of haloarcula marismortui
. SNAP output
|
|
1yit
|
ribosome-antibiotic |
X-ray (2.8 Å) |
TU D, Blaha G, Moore PB, Steitz TA |
(2005) "Structures
of Mlsbk Antibiotics Bound to Mutated Large Ribosomal
Subunits Provide a Structural Explanation for
Resistance." Cell(Cambridge,Mass.),
121, 257. doi: 10.1016/J.CELL.2005.02.005.
|
Crystal structure of virginiamycin m and s bound to the
50s ribosomal subunit of haloarcula marismortui .
SNAP output
|
|
1yj9
|
ribosome |
X-ray (2.8 Å) |
Tu D, Blaha G, Moore PB, Steitz TA |
(2005) "Structures
of MLSBK antibiotics bound to mutated large ribosomal
subunits provide a structural explanation for
resistance." Cell(Cambridge,Mass.),
121, 257-270. doi: 10.1016/j.cell.2005.02.005.
|
Crystal structure of the mutant 50s ribosomal subunit
of haloarcula marismortui containing a three residue
deletion in l22 . SNAP
output
|
|
1yjn
|
ribosome |
X-ray (3.0 Å) |
Tu D, Blaha G, Moore PB, Steitz TA |
(2005) "Structures
of MLSBK antibiotics bound to mutated large ribosomal
subunits provide a structural explanation for
resistance." Cell(Cambridge,Mass.),
121, 257-270. doi: 10.1016/j.cell.2005.02.005.
|
Crystal structure of clindamycin bound to the g2099a
mutant 50s ribosomal subunit of haloarcula marismortui
. SNAP output
|
|
1yjw
|
ribosome-antibiotic |
X-ray (2.9 Å) |
Tu D, Blaha G, Moore PB, Steitz TA |
(2005) "Structures
of Mlsbk Antibiotics Bound to Mutated Large Ribosomal
Subunits Provide a Structural Explanation for
Resistance." Cell(Cambridge,Mass.),
121, 257. doi: 10.1016/J.CELL.2005.02.005.
|
Crystal structure of quinupristin bound to the g2099a
mutant 50s ribosomal subunit of haloarcula marismortui
. SNAP output
|
|
1ysh
|
structural protein-RNA |
cryo-EM (9.5 Å) |
Halic M, Becker T, Frank J, Spahn CM, Beckmann R |
(2005) "Localization
and dynamic behavior of ribosomal protein L30e."
Nat.Struct.Mol.Biol., 12,
467-468. doi: 10.1038/nsmb933.
|
Localization and dynamic behavior of ribosomal protein
l30e . SNAP output
|
|
1ytu
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Ma JB, Yuan YR, Meister G, Pei Y, Tuschl T, Patel
DJ |
(2005) "Structural
basis for 5'-end-specific recognition of guide RNA by
the A. fulgidus Piwi protein." Nature,
434, 666-670. doi: 10.1038/nature03514.
|
Structural basis for 5'-end-specific recognition of the
guide RNA strand by the a. fulgidus piwi protein .
SNAP output
|
|
1yty
|
transcription-RNA |
X-ray (2.29 Å) |
Teplova M, Yuan YR, Phan AT, Malinina L, Ilin S,
Teplov A, Patel DJ |
(2006) "Structural
Basis for Recognition and Sequestration of UUU(OH) 3'
Temini of Nascent RNA Polymerase III Transcripts by La,
a Rheumatic Disease Autoantigen."
Mol.Cell, 21, 75-85. doi:
10.1016/j.molcel.2005.10.027.
|
Structural basis for recognition of uuuoh 3'-terminii
of nascent RNA pol iii transcripts by la autoantigen .
SNAP output
|
|
1yvp
|
RNA binding protein-RNA |
X-ray (2.2 Å) |
Stein AJ, Fuchs G, Fu C, Wolin SL, Reinisch KM |
(2005) "Structural
Insights into RNA Quality Control: The Ro Autoantigen
Binds Misfolded RNAs via Its Central Cavity."
Cell(Cambridge,Mass.), 121,
529-539. doi: 10.1016/j.cell.2005.03.009.
|
Ro autoantigen complexed with rnas . SNAP output
|
|
1yyk
|
hydrolase-RNA |
X-ray (2.5 Å) |
Gan J, Tropea JE, Austin BP, Court DL, Waugh DS, Ji
X |
(2005) "Intermediate
states of ribonuclease III in complex with
double-stranded RNA." Structure,
13, 1435-1442. doi: 10.1016/j.str.2005.06.014.
|
Crystal structure of rnase iii from aquifex aeolicus
complexed with double-stranded RNA at 2.5-angstrom
resolution . SNAP
output
|
|
1yyo
|
hydrolase-RNA |
X-ray (2.9 Å) |
Gan J, Tropea JE, Austin BP, Court DL, Waugh DS, Ji
X |
(2005) "Intermediate
states of ribonuclease III in complex with
double-stranded RNA." Structure,
13, 1435-1442. doi: 10.1016/j.str.2005.06.014.
|
Crystal structure of rnase iii mutant e110k from
aquifex aeolicus complexed with double-stranded RNA at
2.9-angstrom resolution . SNAP output
|
|
1yyw
|
hydrolase-RNA |
X-ray (2.8 Å) |
Gan J, Tropea JE, Austin BP, Court DL, Waugh DS, Ji
X |
(2005) "Intermediate
states of ribonuclease III in complex with
double-stranded RNA." Structure,
13, 1435-1442. doi: 10.1016/j.str.2005.06.014.
|
Crystal structure of rnase iii from aquifex aeolicus
complexed with double stranded RNA at 2.8-angstrom
resolution . SNAP
output
|
|
1yz9
|
hydrolase-RNA |
X-ray (2.1 Å) |
Gan J, Tropea JE, Austin BP, Court DL, Waugh DS, Ji
X |
(2005) "Intermediate
states of ribonuclease III in complex with
double-stranded RNA." Structure,
13, 1435-1442. doi: 10.1016/j.str.2005.06.014.
|
Crystal structure of rnase iii mutant e110q from
aquifex aeolicus complexed with double stranded RNA at
2.1-angstrom resolution . SNAP output
|
|
1zbh
|
hydrolase-RNA |
X-ray (3.0 Å) |
Cheng Y, Patel DJ |
"Structural basis for 3'-end specific recognition of
histone mRNA stem-loop by 3'-exonuclease, a human
nuclease that also targets siRNA." |
3'-end specific recognition of histone mrna stem-loop
by 3'-exonuclease . SNAP
output
|
|
1zbn
|
RNA binding protein-RNA |
NMR |
Calabro V, Daugherty MD, Frankel AD |
(2005) "A single
intermolecular contact mediates intramolecular
stabilization of both RNA and protein."
Proc.Natl.Acad.Sci.Usa, 102,
6849-6854. doi: 10.1073/pnas.0409282102.
|
Solution structure of biv tar hairpin complexed to jdv
tat arginine-rich motif . SNAP output
|
|
1zdh
|
virus-RNA |
X-ray (2.7 Å) |
Valegard K, Murray JB, Stonehouse NJ, van den Worm S,
Stockley PG, Liljas L |
(1997) "The
three-dimensional structures of two complexes between
recombinant MS2 capsids and RNA operator fragments
reveal sequence-specific protein-RNA interactions."
J.Mol.Biol., 270, 724-738.
doi: 10.1006/jmbi.1997.1144.
|
Ms2 coat protein-RNA complex . SNAP output
|
|
1zdi
|
virus-RNA |
X-ray (2.7 Å) |
Valegard K, Murray JB, Stonehouse NJ, van den Worm S,
Stockley PG, Liljas L |
(1997) "The
three-dimensional structures of two complexes between
recombinant MS2 capsids and RNA operator fragments
reveal sequence-specific protein-RNA interactions."
J.Mol.Biol., 270, 724-738.
doi: 10.1006/jmbi.1997.1144.
|
RNA bacteriophage ms2 coat protein-RNA complex .
SNAP output
|
|
1zdj
|
virus-RNA |
X-ray (2.9 Å) |
Grahn E, Stonehouse NJ, Murray JB, van den Worm S,
Valegard K, Fridborg K, Stockley PG, Liljas L |
(1999) "Crystallographic
studies of RNA hairpins in complexes with recombinant
MS2 capsids: implications for binding
requirements." RNA, 5,
131-138. doi: 10.1017/S1355838299981645.
|
Structure of bacteriophage coat protein-loop RNA
complex . SNAP
output
|
|
1zdk
|
virus-RNA |
X-ray (2.86 Å) |
Grahn E, Stonehouse NJ, Murray JB, van den Worm S,
Valegard K, Fridborg K, Stockley PG, Liljas L |
(1999) "Crystallographic
studies of RNA hairpins in complexes with recombinant
MS2 capsids: implications for binding
requirements." RNA, 5,
131-138. doi: 10.1017/S1355838299981645.
|
Structure of bacteriophage coat protein-loop RNA
complex . SNAP
output
|
|
1ze2
|
lyase-RNA |
X-ray (3.0 Å) |
Phannachet K, Huang RH |
(2004) "Conformational
change of pseudouridine 55 synthase upon its
association with RNA substrate." Nucleic Acids
Res., 32, 1422-1429. doi:
10.1093/nar/gkh287.
|
Conformational change of pseudouridine 55 synthase upon
its association with RNA substrate . SNAP output
|
|
1zh5
|
transcription-RNA |
X-ray (1.85 Å) |
Teplova M, Yuan YR, Phan AT, Malinina L, Ilin S,
Teplov A, Patel DJ |
(2006) "Structural
Basis for Recognition and Sequestration of UUU(OH) 3'
Temini of Nascent RNA Polymerase III Transcripts by La,
a Rheumatic Disease Autoantigen."
Mol.Cell, 21, 75-85. doi:
10.1016/j.molcel.2005.10.027.
|
Structural basis for recognition of uuuoh 3'-terminii
of nascent RNA pol iii transcripts by la autoantigen .
SNAP output
|
|
1zho
|
structural protein-RNA |
X-ray (2.6 Å) |
Nevskaya N, Tishchenko S, Volchkov S, Kljashtorny V,
Nikonova E, Nikonov O, Nikulin A, Kohrer C, Piendl W,
Zimmermann R, Stockley P, Garber M, Nikonov S |
(2006) "New
insights into the interaction of ribosomal protein L1
with RNA." J.Mol.Biol.,
355, 747-759. doi: 10.1016/j.jmb.2005.10.084.
|
The structure of a ribosomal protein l1 in complex with
mrna . SNAP output
|
|
1zjw
|
ligase-RNA |
X-ray (2.5 Å) |
Gruic-Sovulj I, Uter N, Bullock T, Perona JJ |
(2005) "tRNA-dependent
Aminoacyl-adenylate Hydrolysis by a Nonediting Class I
Aminoacyl-tRNA Synthetase." J.Biol.Chem.,
280, 23978-23986. doi: 10.1074/jbc.M414260200.
|
Glutaminyl-trna synthetase complexed to glutamine and
2'deoxy a76 glutamine trna . SNAP output
|
|
1zl3
|
lyase-RNA |
X-ray (2.8 Å) |
Hoang C, Hamilton CS, Mueller EG, Ferre-D'Amare
AR |
(2005) "Precursor
complex structure of pseudouridine synthase TruB
suggests coupling of active site perturbations to an
RNA-sequestering peripheral protein domain."
Protein Sci., 14, 2201-2206.
doi: 10.1110/ps.051493605.
|
Coupling of active site motions and RNA binding .
SNAP output
|
|
1zo1
|
translation-RNA |
cryo-EM (13.8 Å) |
Allen GS, Zavialov A, Gursky R, Ehrenberg M, Frank
J |
(2005) "The
Cryo-EM Structure of a Translation Initiation Complex
from Escherichia coli."
Cell(Cambridge,Mass.), 121,
703-712. doi: 10.1016/j.cell.2005.03.023.
|
If2, if1, and trna fitted to cryo-EM data of e. coli
70s initiation complex . SNAP output
|
|
1zse
|
RNA-virus-viral protein |
X-ray (3.0 Å) |
Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ,
Lago H, Adams CJ, Peabody DS, Phillips SEV, Stonehouse
NJ, Liljas L, Stockley PG |
(2006) "Structural
Basis of RNA Binding Discrimination between
Bacteriophages Qbeta and MS2." Structure,
14, 487-495. doi: 10.1016/j.str.2005.12.006.
|
RNA stemloop from bacteriophage qbeta complexed with an
n87s mutant ms2 capsid . SNAP output
|
|
1zzn
|
structural protein-RNA |
X-ray (3.37 Å) |
Stahley MR, Strobel SA |
(2005) "Structural
evidence for a two-metal-ion mechanism of group I
intron splicing." Science,
309, 1587-1590. doi: 10.1126/science.1114994.
|
Crystal structure of a group i intron-two exon complex
that includes all catalytic metal ion ligands. .
SNAP output
|
|
2a1r
|
hydrolase-RNA |
X-ray (2.6 Å) |
Wu M, Reuter M, Lilie H, Liu Y, Wahle E, Song H |
(2005) "Structural
insight into poly(A) binding and catalytic mechanism of
human PARN." Embo J., 24,
4082-4093. doi: 10.1038/sj.emboj.7600869.
|
Crystal structure of parn nuclease domain . SNAP output
|
|
2a8v
|
protein-RNA |
X-ray (2.4 Å) |
Bogden CE, Fass D, Bergman N, Nichols MD, Berger
JM |
(1999) "The
structural basis for terminator recognition by the Rho
transcription termination factor."
Mol.Cell, 3, 487-493. doi:
10.1016/S1097-2765(00)80476-1.
|
Rho transcription termination factor-RNA complex .
SNAP output
|
|
2a9x
|
RNA binding protein-RNA |
NMR |
Leeper TC, Athanassiou Z, Dias RL, Robinson JA,
Varani G |
(2005) "TAR RNA
recognition by a cyclic peptidomimetic of Tat
protein." Biochemistry,
44, 12362-12372. doi: 10.1021/bi0510532.
|
Tar RNA recognition by a cyclic peptidomimetic of tat
protein . SNAP
output
|
|
2ab4
|
isomerase-RNA |
X-ray (2.4 Å) |
Phannachet K, Elias Y, Huang RH |
(2005) "Dissecting
the roles of a strictly conserved tyrosine in substrate
recognition and catalysis by pseudouridine 55
synthase." Biochemistry,
44, 15488-15494. doi: 10.1021/bi050961w.
|
Dissecting the roles of a strictly conserved tyrosine
in substrate recognition and catalysis by pseudouridine
55 synthase . SNAP
output
|
|
2ad9
|
RNA binding protein-RNA |
NMR |
Oberstrass FC, Auweter SD, Erat M, Hargous Y, Henning
A, Wenter P, Reymond L, Amir-Ahmady B, Pitsch S, Black
DL, Allain FHT |
(2005) "Structure
of PTB bound to RNA: specific binding and implications
for splicing regulation." Science,
309, 2054-2057. doi: 10.1126/science.1114066.
|
Solution structure of polypyrimidine tract binding
protein rbd1 complexed with cucucu RNA . SNAP output
|
|
2adb
|
RNA binding protein-RNA |
NMR |
Oberstrass FC, Auweter SD, Erat M, Hargous Y, Henning
A, Wenter P, Reymond L, Amir-Ahmady B, Pitsch S, Black
DL, Allain FHT |
(2005) "Structure
of PTB bound to RNA: specific binding and implications
for splicing regulation." Science,
309, 2054-2057. doi: 10.1126/science.1114066.
|
Solution structure of polypyrimidine tract binding
protein rbd2 complexed with cucucu RNA . SNAP output
|
|
2adc
|
RNA binding protein-RNA |
NMR |
Oberstrass FC, Auweter SD, Erat M, Hargous Y, Henning
A, Wenter P, Reymond L, Amir-Ahmady B, Pitsch S, Black
DL, Allain FHT |
(2005) "Structure
of PTB bound to RNA: specific binding and implications
for splicing regulation." Science,
309, 2054-2057. doi: 10.1126/science.1114066.
|
Solution structure of polypyrimidine tract binding
protein rbd34 complexed with cucucu RNA . SNAP output
|
|
2ake
|
ligase-RNA |
X-ray (3.1 Å) |
Shen N, Guo L, Yang B, Jin Y, Ding J |
(2006) "Structure
of human tryptophanyl-tRNA synthetase in complex with
tRNA(Trp) reveals the molecular basis of tRNA
recognition and specificity." Nucleic Acids
Res., 34, 3246-3258. doi:
10.1093/nar/gkl441.
|
Structure of human tryptophanyl-trna synthetase in
complex with trna(trp) . SNAP output
|
|
2ann
|
RNA-binding protein-RNA |
X-ray (2.3 Å) |
Teplova M, Malinina L, Darnell JC, Song J, Lu M,
Abagyan R, Musunuru K, Teplov A, Burley SK, Darnell RB,
Patel DJ |
(2011) "Protein-RNA
and protein-protein recognition by dual KH1/2 domains
of the neuronal splicing factor Nova-1."
Structure, 19, 930-944. doi:
10.1016/j.str.2011.05.002.
|
Crystal structure (i) of nova-1 kh1-kh2 domain tandem
with 25 nt RNA hairpin . SNAP output
|
|
2anr
|
RNA-binding protein-RNA |
X-ray (1.94 Å) |
Teplova M, Malinina L, Darnell JC, Song J, Lu M,
Abagyan R, Musunuru K, Teplov A, Burley SK, Darnell RB,
Patel DJ |
(2011) "Protein-RNA
and protein-protein recognition by dual KH1/2 domains
of the neuronal splicing factor Nova-1."
Structure, 19, 930-944. doi:
10.1016/j.str.2011.05.002.
|
Crystal structure (ii) of nova-1 kh1-kh2 domain tandem
with 25nt RNA hairpin . SNAP output
|
|
2asb
|
transcription-RNA |
X-ray (1.5 Å) |
Beuth B, Pennell S, Arnvig KB, Martin SR, Taylor
IA |
(2005) "Structure
of a Mycobacterium tuberculosis NusA-RNA complex."
Embo J., 24, 3576-3587. doi:
10.1038/sj.emboj.7600829.
|
Structure of a mycobacterium tuberculosis nusa-RNA
complex . SNAP
output
|
|
2atw
|
transcription-RNA |
X-ray (2.25 Å) |
Beuth B, Pennell S, Arnvig KB, Martin SR, Taylor
IA |
(2005) "Structure
of a Mycobacterium tuberculosis NusA-RNA complex."
Embo J., 24, 3576-3587. doi:
10.1038/sj.emboj.7600829.
|
Structure of a mycobacterium tuberculosis nusa-RNA
complex . SNAP
output
|
|
2az0
|
viral protein-RNA |
X-ray (2.6 Å) |
Chao JA, Lee JH, Chapados BR, Debler EW, Schneemann
A, Williamson JR |
(2005) "Dual
modes of RNA-silencing suppression by Flock House virus
protein B2." Nat.Struct.Mol.Biol.,
12, 952-957. doi: 10.1038/nsmb1005.
|
Flock house virus b2-dsrna complex (p212121) . SNAP output
|
|
2az2
|
viral protein-RNA |
X-ray (2.6 Å) |
Chao JA, Lee JH, Chapados BR, Debler EW, Schneemann
A, Williamson JR |
(2005) "Dual
modes of RNA-silencing suppression by Flock House virus
protein B2." Nat.Struct.Mol.Biol.,
12, 952-957. doi: 10.1038/nsmb1005.
|
Flock house virus b2-dsrna complex (p4122) . SNAP output
|
|
2azx
|
ligase-RNA |
X-ray (2.8 Å) |
Yang XL, Otero FJ, Ewalt KL, Liu J, Swairjo MA,
Kohrer C, RajBhandary UL, Skene RJ, McRee DE, Schimmel
P |
(2006) "Two
conformations of a crystalline human tRNA
synthetase-tRNA complex: implications for protein
synthesis." Embo J., 25,
2919-2929. doi: 10.1038/sj.emboj.7601154.
|
Charged and uncharged trnas adopt distinct
conformations when complexed with human
tryptophanyl-trna synthetase . SNAP output
|
|
2b2d
|
virus-viral protein-RNA |
X-ray (2.9 Å) |
Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ,
Lago H, Adams CJ, Peabody DS, Phillips SEV, Stonehouse
NJ, Liljas L, Stockley PG |
(2006) "Structural
basis of RNA binding discrimination between
bacteriophages Qbeta and MS2." Structure,
14, 487-495. doi: 10.1016/j.str.2005.12.006.
|
RNA stemloop operator from bacteriophage qbeta
complexed with an n87s,e89k mutant ms2 capsid .
SNAP output
|
|
2b2e
|
virus-viral protein-RNA |
X-ray (3.15 Å) |
Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ,
Lago H, Adams CJ, Peabody DS, Phillips SEV, Stonehouse
NJ, Liljas L, Stockley PG |
(2006) "Structural
basis of RNA binding discrimination between
bacteriophages Qbeta and MS2." Structure,
14, 487-495. doi: 10.1016/j.str.2005.12.006.
|
RNA stemloop from bacteriophage ms2 complexed with an
n87s,e89k mutant ms2 capsid . SNAP output
|
|
2b2g
|
virus-viral protein-RNA |
X-ray (3.02 Å) |
Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ,
Lago H, Adams CJ, Peabody DS, Phillips SEV, Stonehouse
NJ, Liljas L, Stockley PG |
(2006) "Structural
basis of RNA binding discrimination between
bacteriophages Qbeta and MS2." Structure,
14, 487-495. doi: 10.1016/j.str.2005.12.006.
|
Ms2 wild-type RNA stemloop complexed with an n87s
mutant ms2 capsid . SNAP
output
|
|
2b3j
|
hydrolase-RNA |
X-ray (2.0 Å) |
Losey HC, Ruthenburg AJ, Verdine GL |
(2006) "Crystal
structure of Staphylococcus aureus tRNA adenosine
deaminase TadA in complex with RNA."
Nat.Struct.Mol.Biol., 13,
153-159. doi: 10.1038/nsmb1047.
|
Crystal structure of staphylococcus aureus trna
adenosine deaminase, tada, in complex with RNA .
SNAP output
|
|
2b63
|
transferase-RNA |
X-ray (3.8 Å) |
Kettenberger H, Eisenfuehr A, Brueckner F, Theis M,
Famulok M, Cramer P |
(2006) "Structure
of an RNA polymerase II-RNA inhibitor complex
elucidates transcription regulation by noncoding
RNAs." Nat.Struct.Mol.Biol.,
13, 44-48. doi: 10.1038/nsmb1032.
|
Complete RNA polymerase ii-RNA inhibitor complex .
SNAP output
|
|
2b6g
|
RNA binding protein |
NMR |
Johnson PE, Donaldson LW |
(2006) "RNA
recognition by the Vts1p SAM domain."
Nat.Struct.Mol.Biol., 13,
177-178. doi: 10.1038/nsmb1039.
|
RNA recognition by the vts1 sam domain . SNAP output
|
|
2bbv
|
virus-RNA |
X-ray (2.8 Å) |
Wery JP, Reddy VS, Hosur MV, Johnson JE |
(1994) "The
refined three-dimensional structure of an insect virus
at 2.8 A resolution." J.Mol.Biol.,
235, 565-586. doi: 10.1006/jmbi.1994.1014.
|
The refined three-dimensional structure of an insect
virus at 2.8 angstroms resolution . SNAP output
|
|
2bgg
|
RNA-binding protein-RNA |
X-ray (2.2 Å) |
Parker JS, Roe SM, Barford D |
(2005) "Structural
Insights Into Mrna Recognition from a Piwi Domain-Sirna
Guide Complex." Nature,
434, 663. doi: 10.1038/NATURE03462.
|
The structure of a piwi protein from archaeoglobus
fulgidus complexed with a 16nt sirna duplex. . SNAP output
|
|
2bh2
|
transferase |
X-ray (2.15 Å) |
Lee TT, Agarwalla S, Stroud RM |
(2005) "A Unique
RNA Fold in the Ruma-RNA-Cofactor Ternary Complex
Contributes to Substrate Selectivity and Enzymatic
Function." Cell(Cambridge,Mass.),
120, 599. doi: 10.1016/J.CELL.2004.12.037.
|
Crystal structure of e. coli 5-methyluridine
methyltransferase ruma in complex with ribosomal RNA
substrate and s-adenosylhomocysteine. . SNAP output
|
|
2bny
|
virus |
X-ray (3.0 Å) |
Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ,
Lago H, Adams CJ, Peabody DS, Phillips SEV, Stonehouse
NJ, Liljas L, Stockley PG |
(2006) "Structural
Basis of RNA Binding Discrimination between
Bacteriophages Qbeta and MS2." Structure,
14, 487. doi: 10.1016/J.STR.2005.12.006.
|
Ms2 (n87a mutant) - RNA hairpin complex . SNAP output
|
|
2bq5
|
virus-RNA |
X-ray (2.91 Å) |
Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ,
Lago H, Adams CJ, Peabody DS, Phillips SEV, Stonehouse
NJ, Liljas L, Stockley PG |
(2006) "Structural
Basis of RNA Binding Discrimination between
Bacteriophages Qbeta and MS2." Structure,
14, 487. doi: 10.1016/J.STR.2005.12.006.
|
Ms2 (n87ae89k mutant) - RNA hairpin complex . SNAP output
|
|
2bs0
|
virus-RNA |
X-ray (2.45 Å) |
Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ,
Lago H, Adams CJ, Peabody DS, Phillips SEV, Stonehouse
NJ, Liljas L, Stockley PG |
(2006) "Structural
Basis of RNA Binding Discrimination between
Bacteriophages Qbeta and MS2." Structure,
14, 487. doi: 10.1016/J.STR.2005.12.006.
|
Ms2 (n87ae89k mutant) - variant qbeta RNA hairpin
complex . SNAP
output
|
|
2bs1
|
virus-RNA |
X-ray (2.8 Å) |
Horn WT, Tars K, Grahn E, Helgstrand C, Baron AJ,
Lago H, Adams CJ, Peabody DS, Phillips SEV, Stonehouse
NJ, Liljas L, Stockley PG |
(2006) "Structural
Basis of RNA Binding Discrimination between
Bacteriophages Qbeta and MS2." Structure,
14, 487. doi: 10.1016/J.STR.2005.12.006.
|
Ms2 (n87ae89k mutant) - qbeta RNA hairpin complex .
SNAP output
|
|
2bte
|
ligase |
X-ray (2.9 Å) |
Tukalo M, Yaremchuk A, Fukunaga R, Yokoyama S, Cusack
S |
(2005) "The
Crystal Structure of Leucyl-tRNA Synthetase Complexed
with tRNA(Leu) in the Post-Transfer- Editing
Conformation." Nat.Struct.Mol.Biol.,
12, 923. doi: 10.1038/NSMB986.
|
Thermus thermophilus leucyl-trna synthetase complexed
with a trnaleu transcript in the post-editing
conformation and a post- transfer editing substrate
analogue . SNAP
output
|
|
2bu1
|
virus-RNA |
X-ray (2.2 Å) |
Grahn E, Moss T, Helgstrand C, Fridborg K, Sundaram
M, Tars K, Lago H, Stonehouse NJ, Davis DR, Stockley PG,
Liljas L |
(2001) "Structural
basis of pyrimidine specificity in the MS2 RNA
hairpin-coat-protein complex." Rna,
7, 1616-1627.
|
Ms2-RNA hairpin (5bru -5) complex . SNAP output
|
|
2bx2
|
hydrolase |
X-ray (2.85 Å) |
Callaghan AJ, Marcaida MJ, Stead JA, Mcdowall KJ,
Scott WG, Luisi BF |
(2005) "Structure
of E. Coli Rnase E Catalytic Domain and Implications
for RNA Processing and Turnover." Nature,
437, 1187. doi: 10.1038/NATURE04084.
|
Catalytic domain of e. coli rnase e . SNAP output
|
|
2byt
|
synthetase |
X-ray (3.3 Å) |
Tukalo M, Yaremchuk A, Fukunaga R, Yokoyama S, Cusack
S |
(2005) "The
Crystal Structure of Leucyl-tRNA Synthetase Complexed
with tRNA(Leu) in the Post-Transfer-Editing
Conformation." Nat.Struct.Mol.Biol.,
12, 923. doi: 10.1038/NSMB986.
|
Thermus thermophilus leucyl-trna synthetase complexed
with a trnaleu transcript in the post-editing
conformation . SNAP
output
|
|
2c06
|
toxin |
NMR |
Kamphuis MB, Bonvin AMJJ, Monti MC, Lemonnier M,
Munoz-Gomez A, Van Den Heuvel RHH, Diaz-Orejas R, Boelens
R |
(2006) "Model
for RNA Binding and the Catalytic Site of the Rnase Kid
of the Bacterial Pard Toxin-Antitoxin System."
J.Mol.Biol., 357, 115. doi:
10.1016/J.JMB.2005.12.033.
|
NMR-based model of the complex of the toxin kid and a
5-nucleotide substrate RNA fragment (auaca) . SNAP output
|
|
2c0b
|
hydrolase |
X-ray (3.18 Å) |
Callaghan AJ, Marcaida MJ, Stead JA, Mcdowall KJ,
Scott WG, Luisi BF |
(2005) "Structure
of E. Coli Rnase E Catalytic Domain and Implications
for RNA Processing and Turnover." Nature,
437, 1187. doi: 10.1038/NATURE04084.
|
Catalytic domain of e. coli rnase e in complex with
13-mer RNA . SNAP
output
|
|
2c4q
|
virus-RNA |
X-ray (2.38 Å) |
Grahn E, Moss T, Helgstrand C, Fridborg K, Sundaram
M, Tars K, Lago H, Stonehouse NJ, Davis DR, Stockley PG,
Liljas L |
(2001) "Structural
basis of pyrimidine specificity in the MS2 RNA
hairpin-coat-protein complex." Rna,
7, 1616-1627.
|
Ms2-RNA hairpin (2one -5) complex . SNAP output
|
|
2c4r
|
hydrolase |
X-ray (3.6 Å) |
Callaghan AJ, Marcaida MJ, Stead JA, McDowall KJ,
Scott WG, Luisi BF |
(2005) "Structure
of E. Coli Rnase E Catalytic Domain and Implications
for RNA Processing and Turnover." Nature,
437, 1187. doi: 10.1038/NATURE04084.
|
Catalytic domain of e. coli rnase e . SNAP output
|
|
2c4y
|
virus-RNA |
X-ray (2.68 Å) |
Grahn E, Moss T, Helgstrand C, Fridborg K, Sundaram
M, Tars K, Lago H, Stonehouse NJ, Davis DR, Stockley PG,
Liljas L |
(2001) "Structural
basis of pyrimidine specificity in the MS2 RNA
hairpin-coat-protein complex." Rna,
7, 1616-1627.
|
Ms2-RNA hairpin (2thiouracil-5) complex . SNAP output
|
|
2c4z
|
virus-RNA |
X-ray (2.6 Å) |
Grahn E, Moss T, Helgstrand C, Fridborg K, Sundaram
M, Tars K, Lago H, Stonehouse NJ, Davis DR, Stockley PG,
Liljas L |
(2001) "Structural
basis of pyrimidine specificity in the MS2 RNA
hairpin-coat-protein complex." Rna,
7, 1616-1627.
|
Ms2-RNA hairpin (2su -5-6) complex . SNAP output
|
|
2c50
|
virus-RNA |
X-ray (2.65 Å) |
Grahn E, Moss T, Helgstrand C, Fridborg K, Sundaram
M, Tars K, Lago H, Stonehouse NJ, Davis DR, Stockley PG,
Liljas L |
(2001) "Structural
basis of pyrimidine specificity in the MS2 RNA
hairpin-coat-protein complex." Rna,
7, 1616-1627.
|
Ms2-RNA hairpin (a -5) complex . SNAP output
|
|
2c51
|
virus-RNA |
X-ray (2.8 Å) |
Grahn E, Moss T, Helgstrand C, Fridborg K, Sundaram
M, Tars K, Lago H, Stonehouse NJ, Davis DR, Stockley PG,
Liljas L |
(2001) "Structural
basis of pyrimidine specificity in the MS2 RNA
hairpin-coat-protein complex." Rna,
7, 1616-1627.
|
Ms2-RNA hairpin (g -5) complex . SNAP output
|
|
2cjk
|
RNA binding protein |
NMR |
Perez-Canadillas JM |
(2006) "Grabbing
the message: structural basis of mRNA 3'UTR recognition
by Hrp1." EMBO J., 25,
3167-3178. doi: 10.1038/sj.emboj.7601190.
|
Structure of the RNA binding domain of hrp1 in complex
with RNA . SNAP
output
|
|
2csx
|
ligase-RNA |
X-ray (2.7 Å) |
Nakanishi K, Ogiso Y, Nakama T, Fukai S, Nureki
O |
(2005) "Structural
basis for anticodon recognition by methionyl-tRNA
synthetase." Nat.Struct.Mol.Biol.,
12, 931-932. doi: 10.1038/nsmb988.
|
Crystal structure of aquifex aeolicus methionyl-trna
synthetase complexed with trna(met) . SNAP output
|
|
2ct8
|
ligase-RNA |
X-ray (2.7 Å) |
Nakanishi K, Ogiso Y, Nakama T, Fukai S, Nureki
O |
(2005) "Structural
basis for anticodon recognition by methionyl-tRNA
synthetase." Nat.Struct.Mol.Biol.,
12, 931-932. doi: 10.1038/nsmb988.
|
Crystal structure of aquifex aeolicus methionyl-trna
synthetase complexed with trna(met) and
methionyl-adenylate anologue . SNAP output
|
|
2cv0
|
ligase-RNA |
X-ray (2.4 Å) |
Sekine S, Shichiri M, Bernier S, Chenevert R,
Lapointe J, Yokoyama S |
(2006) "Structural
bases of transfer RNA-dependent amino acid recognition
and activation by glutamyl-tRNA synthetase."
Structure, 14, 1791-1799.
doi: 10.1016/j.str.2006.10.005.
|
Glutamyl-trna synthetase from thermus thermophilus in
complex with trna(glu) and l-glutamate . SNAP output
|
|
2cv1
|
ligase-RNA |
X-ray (2.41 Å) |
Sekine S, Yokoyama S |
"Glutamyl-tRNA synthetase from Thermus thermophilus
in complex with tRNA(Glu), ATP, and an analog of
L-glutamate: a quaternary complex." |
Glutamyl-trna synthetase from thermus thermophilus in
complex with trna(glu), atp, and an analog of
l-glutamate: a quaternary complex . SNAP output
|
|
2cv2
|
ligase-RNA |
X-ray (2.69 Å) |
Sekine S, Shichiri M, Bernier S, Chenevert R,
Lapointe J, Yokoyama S |
(2006) "Structural
bases of transfer RNA-dependent amino acid recognition
and activation by glutamyl-tRNA synthetase."
Structure, 14, 1791-1799.
doi: 10.1016/j.str.2006.10.005.
|
Glutamyl-trna synthetase from thermus thermophilus in
complex with trna(glu) and an enzyme inhibitor, glu-ams
. SNAP output
|
|
2czj
|
RNA binding protein-RNA |
X-ray (3.01 Å) |
Bessho Y, Shibata R, Sekine S, Murayama K,
Higashijima K, Hori-Takemoto C, Shirouzu M, Kuramitsu S,
Yokoyama S |
(2007) "Structural
basis for functional mimicry of long-variable-arm tRNA
by transfer-messenger RNA."
Proc.Natl.Acad.Sci.Usa, 104,
8293-8298. doi: 10.1073/pnas.0700402104.
|
Crystal structure of the trna domain of tmrna from
thermus thermophilus hb8 . SNAP output
|
|
2d3o
|
ribosome |
X-ray (3.35 Å) |
Schlunzen F, Wilson DN, Tian P, Harms JM, McInnes SJ,
Hansen HA, Albrecht R, Buerger J, Wilbanks SM, Fucini
P |
(2005) "The
Binding Mode of the Trigger Factor on the Ribosome:
Implications for Protein Folding and SRP
Interaction." Structure,
13, 1685-1694. doi: 10.1016/j.str.2005.08.007.
|
Structure of ribosome binding domain of the trigger
factor on the 50s ribosomal subunit from d. radiodurans
. SNAP output
|
|
2d6f
|
ligase-RNA |
X-ray (3.15 Å) |
Oshikane H, Sheppard K, Fukai S, Nakamura Y, Ishitani
R, Numata T, Sherrer RL, Feng L, Schmitt E, Panvert M,
Blanquet S, Mechulam Y, Soll D, Nureki O |
(2006) "Structural
basis of RNA-dependent recruitment of glutamine to the
genetic code." Science,
312, 1950-1954. doi: 10.1126/science.1128470.
|
Crystal structure of glu-trna(gln) amidotransferase in
the complex with trna(gln) . SNAP output
|
|
2der
|
transferase-RNA |
X-ray (3.1 Å) |
Numata T, Ikeuchi Y, Fukai S, Suzuki T, Nureki O |
(2006) "Snapshots
of tRNA sulphuration via an adenylated
intermediate." Nature,
442, 419-424. doi: 10.1038/nature04896.
|
Cocrystal structure of an RNA sulfuration enzyme mnma
and trna-glu in the initial trna binding state .
SNAP output
|
|
2det
|
transferase-RNA |
X-ray (3.4 Å) |
Numata T, Ikeuchi Y, Fukai S, Suzuki T, Nureki O |
(2006) "Snapshots
of tRNA sulphuration via an adenylated
intermediate." Nature,
442, 419-424. doi: 10.1038/nature04896.
|
Cocrystal structure of an RNA sulfuration enzyme mnma
and trna-glu in the pre-reaction state . SNAP output
|
|
2deu
|
transferase-RNA |
X-ray (3.4 Å) |
Numata T, Ikeuchi Y, Fukai S, Suzuki T, Nureki O |
(2006) "Snapshots
of tRNA sulphuration via an adenylated
intermediate." Nature,
442, 419-424. doi: 10.1038/nature04896.
|
Cocrystal structure of an RNA sulfuration enzyme mnma
and trna-glu in the adenylated intermediate state .
SNAP output
|
|
2dr2
|
ligase-RNA |
X-ray (3.0 Å) |
Shen N, Guo L, Yang B, Jin Y, Ding J |
(2006) "Structure
of human tryptophanyl-tRNA synthetase in complex with
tRNA(Trp) reveals the molecular basis of tRNA
recognition and specificity." Nucleic Acids
Res., 34, 3246-3258. doi:
10.1093/nar/gkl441.
|
Structure of human tryptophanyl-trna synthetase in
complex with trna(trp) . SNAP output
|
|
2dr5
|
transferase-RNA |
X-ray (2.8 Å) |
Tomita K, Ishitani R, Fukai S, Nureki O |
(2006) "Complete
crystallographic analysis of the dynamics of CCA
sequence addition." Nature,
443, 956-960. doi: 10.1038/nature05204.
|
Complex structure of cca adding enzyme with mini-helix
lacking cca . SNAP
output
|
|
2dr7
|
transferase-RNA |
X-ray (2.8 Å) |
Tomita K, Ishitani R, Fukai S, Nureki O |
(2006) "Complete
crystallographic analysis of the dynamics of CCA
sequence addition." Nature,
443, 956-960. doi: 10.1038/nature05204.
|
Complex structure of cca-adding enzyme with trnaminidc
. SNAP output
|
|
2dr8
|
transferase-RNA |
X-ray (2.5 Å) |
Tomita K, Ishitani R, Fukai S, Nureki O |
(2006) "Complete
crystallographic analysis of the dynamics of CCA
sequence addition." Nature,
443, 956-960. doi: 10.1038/nature05204.
|
Complex structure of cca-adding enzyme with trnaminidc
and ctp . SNAP
output
|
|
2dr9
|
transferase-RNA |
X-ray (2.8 Å) |
Tomita K, Ishitani R, Fukai S, Nureki O |
(2006) "Complete
crystallographic analysis of the dynamics of CCA
sequence addition." Nature,
443, 956-960. doi: 10.1038/nature05204.
|
Complex structure of cca-adding enzyme with trnaminidcc
. SNAP output
|
|
2dra
|
transferase-RNA |
X-ray (2.5 Å) |
Tomita K, Ishitani R, Fukai S, Nureki O |
(2006) "Complete
crystallographic analysis of the dynamics of CCA
sequence addition." Nature,
443, 956-960. doi: 10.1038/nature05204.
|
Complex structure of cca-adding enzyme with trnaminidcc
and atp . SNAP
output
|
|
2drb
|
transferase-RNA |
X-ray (2.8 Å) |
Tomita K, Ishitani R, Fukai S, Nureki O |
(2006) "Complete
crystallographic analysis of the dynamics of CCA
sequence addition." Nature,
443, 956-960. doi: 10.1038/nature05204.
|
Complex structure of cca-adding enzyme with trnaminicca
. SNAP output
|
|
2du3
|
ligase-RNA |
X-ray (2.6 Å) |
Fukunaga R, Yokoyama S |
(2007) "Structural
insights into the first step of RNA-dependent cysteine
biosynthesis in archaea."
Nat.Struct.Mol.Biol., 14,
272-279. doi: 10.1038/nsmb1219.
|
Crystal structure of archaeoglobus fulgidus
o-phosphoseryl-trna synthetase complexed with trnacys
and o-phosphoserine . SNAP output
|
|
2du4
|
ligase-RNA |
X-ray (2.8 Å) |
Fukunaga R, Yokoyama S |
(2007) "Structural
insights into the first step of RNA-dependent cysteine
biosynthesis in archaea."
Nat.Struct.Mol.Biol., 14,
272-279. doi: 10.1038/nsmb1219.
|
Crystal structure of archaeoglobus fulgidus
o-phosphoseryl-trna synthetase complexed with trnacys .
SNAP output
|
|
2du5
|
ligase-RNA |
X-ray (3.2 Å) |
Fukunaga R, Yokoyama S |
(2007) "Structural
insights into the first step of RNA-dependent cysteine
biosynthesis in archaea."
Nat.Struct.Mol.Biol., 14,
272-279. doi: 10.1038/nsmb1219.
|
Crystal structure of archaeoglobus fulgidus
o-phosphoseryl-trna synthetase e418n-e420n mutant
complexed with trnaopal and o-phosphoserine ("opal
complex") . SNAP
output
|
|
2du6
|
ligase-RNA |
X-ray (3.3 Å) |
Fukunaga R, Yokoyama S |
(2007) "Structural
insights into the first step of RNA-dependent cysteine
biosynthesis in archaea."
Nat.Struct.Mol.Biol., 14,
272-279. doi: 10.1038/nsmb1219.
|
Crystal structure of archaeoglobus fulgidus
o-phosphoseryl-trna synthetase e418n-e420n mutant
complexed with trnaamber and o-phosphoserine ("amber
complex") . SNAP
output
|
|
2dvi
|
transferase-RNA |
X-ray (2.61 Å) |
Tomita K, Ishitani R, Fukai S, Nureki O |
(2006) "Complete
crystallographic analysis of the dynamics of CCA
sequence addition." Nature,
443, 956-960. doi: 10.1038/nature05204.
|
Complex structure of cca-adding enzyme, mini-dcc and
ctp . SNAP output
|
|
2dxi
|
ligase-RNA |
X-ray (2.2 Å) |
Sekine S, Shichiri M, Bernier S, Chenevert R,
Lapointe J, Yokoyama S |
(2006) "Structural
bases of transfer RNA-dependent amino acid recognition
and activation by glutamyl-tRNA synthetase."
Structure, 14, 1791-1799.
doi: 10.1016/j.str.2006.10.005.
|
2.2 a crystal structure of glutamyl-trna synthetase
from thermus thermophilus complexed with trna(glu),
atp, and l-glutamol . SNAP output
|
|
2e5l
|
ribosome |
X-ray (3.3 Å) |
Kaminishi T, Wilson DN, Takemoto C, Harms JM, Kawazoe
M, Schluenzen F, Hanawa-Suetsugu K, Shirouzu M, Fucini P,
Yokoyama S |
(2007) "A
snapshot of the 30S ribosomal subunit capturing mRNA
via the Shine-Dalgarno interaction."
Structure, 15, 289-297. doi:
10.1016/j.str.2006.12.008.
|
A snapshot of the 30s ribosomal subunit capturing mrna
via the shine- dalgarno interaction . SNAP output
|
|
2e9r
|
transferase-RNA |
X-ray (2.81 Å) |
Ferrer-Orta C, Arias A, Perez-Luque R, Escarmis C,
Domingo E, Verdaguer N |
(2007) "Sequential
structures provide insights into the fidelity of RNA
replication." Proc.Natl.Acad.Sci.Usa,
104, 9463-9468. doi: 10.1073/pnas.0700518104.
|
Foot-and-mouth disease virus RNA-dependent RNA
polymerase in complex with a template-primer RNA and
with ribavirin . SNAP
output
|
|
2e9t
|
transferase-RNA |
X-ray (2.6 Å) |
Ferrer-Orta C, Arias A, Perez-Luque R, Escarmis C,
Domingo E, Verdaguer N |
(2007) "Sequential
structures provide insights into the fidelity of RNA
replication." Proc.Natl.Acad.Sci.Usa,
104, 9463-9468. doi: 10.1073/pnas.0700518104.
|
Foot-and-mouth disease virus RNA-polymerase RNA
dependent in complex with a template-primer RNA and
5f-utp . SNAP output
|
|
2e9z
|
transferase-RNA |
X-ray (3.0 Å) |
Ferrer-Orta C, Arias A, Perez-Luque R, Escarmis C,
Domingo E, Verdaguer N |
(2007) "Sequential
structures provide insights into the fidelity of RNA
replication." Proc.Natl.Acad.Sci.Usa,
104, 9463-9468. doi: 10.1073/pnas.0700518104.
|
Foot-and-mouth disease virus RNA-polymerase in complex
with a template- primer RNA, atp and utp . SNAP output
|
|
2ec0
|
transferase-RNA |
X-ray (2.75 Å) |
Ferrer-Orta C, Arias A, Perez-Luque R, Escarmis C,
Domingo E, Verdaguer N |
(2007) "Sequential
structures provide insights into the fidelity of RNA
replication." Proc.Natl.Acad.Sci.Usa,
104, 9463-9468. doi: 10.1073/pnas.0700518104.
|
RNA-dependent RNA polymerase of foot-and-mouth disease
virus in complex with a template-primer RNA and atp .
SNAP output
|
|
2err
|
RNA binding protein |
NMR |
Auweter SD, Fasan R, Reymond L, Underwood JG, Black
DL, Pitsch S, Allain FH |
(2006) "Molecular
basis of RNA recognition by the human alternative
splicing factor Fox-1." Embo J.,
25, 163-173. doi: 10.1038/sj.emboj.7600918.
|
NMR structure of the RNA binding domain of human fox-1
in complex with ugcaugu . SNAP output
|
|
2ese
|
protein-RNA complex |
NMR |
Oberstrass FC, Lee A, Stefl R, Janis M, Chanfreau G,
Allain FH |
(2006) "Shape-specific
recognition in the structure of the Vts1p SAM domain
with RNA." Nat.Struct.Mol.Biol.,
13, 160-167. doi: 10.1038/nsmb1038.
|
Structure of the sam domain of vts1p in complex with
RNA . SNAP output
|
|
2ez6
|
hydrolase-RNA |
X-ray (2.05 Å) |
Gan J, Tropea JE, Austin BP, Court DL, Waugh DS, Ji
X |
(2006) "Structural
Insight into the Mechanism of Double-Stranded RNA
Processing by Ribonuclease III."
Cell(Cambridge,Mass.), 124,
355-366. doi: 10.1016/j.cell.2005.11.034.
|
Crystal structure of aquifex aeolicus rnase iii (d44n)
complexed with product of double-stranded RNA
processing . SNAP
output
|
|
2f4v
|
ribosome |
X-ray (3.8 Å) |
Murray JB, Meroueh SO, Russell RJ, Lentzen G, Haddad
J, Mobashery S |
(2006) "Interactions
of designer antibiotics and the bacterial ribosome
aminoacyl-tRNA site." Chem.Biol.,
13, 129-138. doi: 10.1016/j.chembiol.2005.11.004.
|
30s ribosome + designer antibiotic . SNAP output
|
|
2f8k
|
RNA binding protein- RNA |
X-ray (2.0 Å) |
Aviv T, Lin Z, Ben-Ari G, Smibert CA, Sicheri F |
(2006) "Sequence-specific
recognition of RNA hairpins by the SAM domain of
Vts1p." Nat.Struct.Mol.Biol.,
13, 168-176. doi: 10.1038/nsmb1053.
|
Sequence specific recognition of RNA hairpins by the
sam domain of vts1 . SNAP output
|
|
2f8s
|
RNA binding protein-RNA |
X-ray (3.0 Å) |
Yuan YR, Pei Y, Chen HY, Tuschl T, Patel DJ |
(2006) "A
Potential Protein-RNA Recognition Event along the
RISC-Loading Pathway from the Structure of A. aeolicus
Argonaute with Externally Bound siRNA."
Structure, 14, 1557-1565.
doi: 10.1016/j.str.2006.08.009.
|
Crystal structure of aa-ago with externally-bound sirna
. SNAP output
|
|
2f8t
|
RNA binding protein-RNA |
X-ray (3.1 Å) |
Yuan YR, Pei Y, Chen HY, Tuschl T, Patel DJ |
(2006) "A
Potential Protein-RNA Recognition Event along the
RISC-Loading Pathway from the Structure of A. aeolicus
Argonaute with Externally Bound siRNA."
Structure, 14, 1557-1565.
doi: 10.1016/j.str.2006.08.009.
|
Crystal structure of aa-ago with externally-bound sirna
. SNAP output
|
|
2fk6
|
hydrolase-RNA |
X-ray (2.9 Å) |
Li de la Sierra-Gallay I, Mathy N, Pellegrini O,
Condon C |
(2006) "Structure
of the ubiquitous 3' processing enzyme RNase Z bound to
transfer RNA." Nat.Struct.Mol.Biol.,
13, 376-377. doi: 10.1038/nsmb1066.
|
Crystal structure of rnase z-trna(thr) complex .
SNAP output
|
|
2fmt
|
complex (methyltransferase-trna) |
X-ray (2.8 Å) |
Schmitt E, Panvert M, Blanquet S, Mechulam Y |
(1998) "Crystal
structure of methionyl-tRNAfMet transformylase
complexed with the initiator
formyl-methionyl-tRNAfMet." EMBO J.,
17, 6819-6826. doi: 10.1093/emboj/17.23.6819.
|
Methionyl-trnafmet formyltransferase complexed with
formyl-methionyl-trnafmet . SNAP output
|
|
2fy1
|
structural protein-RNA |
NMR |
Skrisovska L, Bourgeois CF, Stefl R, Grellscheid SN,
Kister L, Wenter P, Elliott DJ, Stevenin J, Allain
FH |
(2007) "The
testis-specific human protein RBMY recognizes RNA
through a novel mode of interaction." EMBO
Rep., 8, 372-379. doi: 10.1038/sj.embor.7400910.
|
A dual mode of RNA recognition by the rbmy protein .
SNAP output
|
|
2fz2
|
virus-RNA |
X-ray (2.9 Å) |
Larson SB, Lucas RW, Greenwood A, McPherson A |
(2005) "The RNA
of turnip yellow mosaic virus exhibits icosahedral
order." Virology, 334,
245-254. doi: 10.1016/j.virol.2005.01.036.
|
Structure of turnip yellow mosaic virus at 100 k .
SNAP output
|
|
2g4b
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Sickmier EA, Frato KE, Paranawithana S, Shen H, Green
MR, Kielkopf CL |
(2006) "Structural
basis of polypyrimidine tract recognition by the
essential splicing factor U2AF65.."
Mol.Cell, 23, 49-59. doi:
10.1016/j.molcel.2006.05.025.
|
Structure of u2af65 variant with polyuridine tract .
SNAP output
|
|
2gic
|
virus-viral protein-RNA |
X-ray (2.92 Å) |
Green TJ, Zhang X, Wertz GW, Luo M |
(2006) "Structure
of the vesicular stomatitis virus nucleoprotein-RNA
complex unveils how the RNA is sequestered."
Science, 313, 357-360. doi:
10.1126/science.1126953.
|
Crystal structure of a vesicular stomatitis virus
nucleocapsid-RNA complex . SNAP output
|
|
2gje
|
translation-RNA |
X-ray (3.37 Å) |
Schumacher MA, Karamooz E, Zikova A, Trantirek L,
Lukes J |
(2006) "Crystal
Structures of T. brucei MRP1/MRP2 Guide-RNA Binding
Complex Reveal RNA Matchmaking Mechanism."
Cell(Cambridge,Mass.), 126,
701-711. doi: 10.1016/j.cell.2006.06.047.
|
Structure of a guiderna-binding protein complex bound
to a grna . SNAP
output
|
|
2gjw
|
hydrolase-RNA |
X-ray (2.85 Å) |
Xue S, Calvin K, Li H |
(2006) "RNA
Recognition and Cleavage by an Splicing
Endonuclease." Science,
312, 902-910. doi: 10.1126/science.1126629.
|
RNA recognition and cleavage by an splicing
endonuclease . SNAP
output
|
|
2go5
|
translation-RNA |
cryo-EM (7.4 Å) |
Halic M, Gartmann M, Schlenker O, Mielke T, Pool MR,
Sinning I, Beckmann R |
(2006) "Signal
Recognition Particle Receptor Exposes the Ribosomal
Translocon Binding Site." Science,
312, 745-747. doi: 10.1126/science.1124864.
|
Structure of signal recognition particle receptor (sr)
in complex with signal recognition particle (srp) and
ribosome nascent chain complex . SNAP output
|
|
2gtt
|
viral protein, RNA binding protein |
X-ray (3.49 Å) |
Albertini AAV, Wernimont AK, Muziol T, Ravelli RBG,
Clapier CR, Schoehn G, Weissenhorn W, Ruigrok RWH |
(2006) "Crystal
Structure of the Rabies Virus Nucleoprotein-RNA
Complex." Science, 313,
360-363. doi: 10.1126/science.1125280.
|
Crystal structure of the rabies virus nucleoprotein-RNA
complex . SNAP
output
|
|
2gxb
|
hydrolase-RNA |
X-ray (2.25 Å) |
Placido D, Brown BA, Lowenhaupt K, Rich A,
Athanasiadis A |
(2007) "A
Left-Handed RNA Double Helix Bound by the Zalpha Domain
of the RNA-Editing Enzyme ADAR1."
Structure, 15, 395-404. doi:
10.1016/j.str.2007.03.001.
|
Crystal structure of the za domain bound to z-RNA .
SNAP output
|
|
2hgh
|
transcription-RNA |
NMR |
Lee BM, Xu J, Clarkson BK, Martinez-Yamout MA, Dyson
JH, Case DA, Gottesfeld JM, Wright PE |
(2006) "Induced
Fit and 'Lock and Key' Recognition of 5 S RNA by Zinc
Fingers of Transcription Factor IIIA."
J.Mol.Biol., 357, 275-291.
doi: 10.1016/j.jmb.2005.12.010.
|
Transcription factor iiia zinc fingers 4-6 bound to 5s
rrna 55mer (NMR structure) . SNAP output
|
|
2hhh
|
ribosome |
X-ray (3.35 Å) |
Schluenzen F, Takemoto C, Wilson DN, Kaminishi T,
Harms JM, Hanawa-Suetsugu K, Szaflarski W, Kawazoe M,
Shirouzo M, Nierhaus KH, Yokoyama S, Fucini P |
(2006) "The
antibiotic kasugamycin mimics mRNA nucleotides to
destabilize tRNA binding and inhibit canonical
translation initiation."
Nat.Struct.Mol.Biol., 13,
871-878. doi: 10.1038/nsmb1145.
|
Crystal structure of kasugamycin bound to the 30s
ribosomal subunit . SNAP
output
|
|
2ht1
|
hydrolase-RNA |
X-ray (3.51 Å) |
Skordalakes E, Berger JM |
(2006) "Structural
Insights into RNA-Dependent Ring Closure and ATPase
Activation by the Rho Termination Factor."
Cell(Cambridge,Mass.), 127,
553-564. doi: 10.1016/j.cell.2006.08.051.
|
The closed ring structure of the rho transcription
termination factor in complex with nucleic acid in the
motor domains . SNAP
output
|
|
2hw8
|
structural protein-RNA |
X-ray (2.1 Å) |
Tishchenko S, Nikonova E, Nikulin A, Nevskaya N,
Volchkov S, Piendl W, Garber M, Nikonov S |
(2006) "Structure
of the ribosomal protein L1-mRNA complex at 2.1 A
resolution: common features of crystal packing of
L1-RNA complexes." ACTA
CRYSTALLOGR.,SECT.D, 62,
1545-1554. doi: 10.1107/S0907444906041655.
|
Structure of ribosomal protein l1-mrna complex at 2.1
resolution. . SNAP
output
|
|
2hyi
|
hydrolase-RNA binding protein-RNA |
X-ray (2.3 Å) |
Andersen CBF, Ballut L, Johansen JS, Chamieh H,
Nielsen KH, Oliveira CL, Pedersen JS, Seraphin B, Le Hir
H, Andersen GR |
(2006) "Structure
of the exon junction core complex with a trapped
DEAD-box ATPase bound to RNA." Science,
313, 1968-1972. doi: 10.1126/science.1131981.
|
Structure of the human exon junction complex with a
trapped dead-box helicase bound to RNA . SNAP output
|
|
2i2y
|
RNA binding protein-chimera-RNA |
NMR |
Hargous Y, Hautbergue GM, Tintaru AM, Skrisovska L,
Golovanov AP, Stevenin J, Lian LY, Wilson SA, Allain
FH |
(2006) "Molecular
basis of RNA recognition and TAP binding by the SR
proteins SRp20 and 9G8." Embo J.,
25, 5126-5137. doi: 10.1038/sj.emboj.7601385.
|
Solution structure of the rrm of srp20 bound to the RNA
cauc . SNAP output
|
|
2i82
|
lyase-RNA |
X-ray (2.05 Å) |
Hoang C, Chen J, Vizthum CA, Kandel JM, Hamilton CS,
Mueller EG, Ferre-D'Amare AR |
(2006) "Crystal
structure of pseudouridine synthase RluA: indirect
sequence readout through protein-induced RNA
structure." Mol.Cell, 24,
535-545. doi: 10.1016/j.molcel.2006.09.017.
|
Crystal structure of pseudouridine synthase rlua:
indirect sequence readout through protein-induced RNA
structure . SNAP
output
|
|
2i91
|
RNA binding protein-RNA |
X-ray (2.65 Å) |
Fuchs G, Stein AJ, Fu C, Reinisch KM, Wolin SL |
(2006) "Structural
and biochemical basis for misfolded RNA recognition by
the Ro autoantigen." Nat.Struct.Mol.Biol.,
13, 1002-1009. doi: 10.1038/nsmb1156.
|
60kda ro autoantigen in complex with a fragment of
misfolded RNA . SNAP
output
|
|
2ihx
|
viral protein-RNA |
NMR |
Zhou J, Bean RL, Vogt VM, Summers M |
(2007) "Solution
Structure of the Rous Sarcoma Virus Nucleocapsid
Protein: muPsi RNA Packaging Signal Complex."
J.Mol.Biol., 365, 453-467.
doi: 10.1016/j.jmb.2006.10.013.
|
Solution structure of the rous sarcoma virus
nucleocapsid protein:upsi RNA packaging signal complex
. SNAP output
|
|
2ix1
|
hydrolase |
X-ray (2.74 Å) |
Frazao C, Mcvey CE, Amblar M, Barbas A, Vonrhein C,
Arraiano CM, Carrondo MA |
(2006) "Unravelling
the Dynamics of RNA Degradation by Ribonuclease II and
its RNA-Bound Complex." Nature,
443, 110. doi: 10.1038/NATURE05080.
|
Rnase ii d209n mutant . SNAP output
|
|
2iy5
|
ligase |
X-ray (3.1 Å) |
Moor N, Kotik-Kogan O, Tworowski D, Sukhanova M,
Safro M |
(2006) "The
crystal structure of the ternary complex of
phenylalanyl-tRNA synthetase with tRNAPhe and a
phenylalanyl-adenylate analogue reveals a
conformational switch of the CCA end."
Biochemistry, 45,
10572-10583. doi: 10.1021/bi060491l.
|
Phenylalanyl-trna synthetase from thermus thermophilus
complexed with trna and a phenylalanyl-adenylate analog
. SNAP output
|
|
2iz8
|
virus-RNA |
X-ray (3.3 Å) |
Helgstrand C, Grahn E, Moss T, Stonehouse NJ, Tars K,
Stockley PG, Liljas L |
(2002) "Investigating
the Structural Basis of Purine Specificity in the
Structures of MS2 Coat Protein RNA Translational
Operator Hairpins." Nucleic Acids Res.,
30, 2678. doi: 10.1093/NAR/GKF371.
|
Ms2-RNA hairpin (c-7) complex . SNAP output
|
|
2iz9
|
virus-RNA |
X-ray (2.85 Å) |
Grahn E, Stonehouse NJ, Adams CJ, Fridborg K,
Beigelman L, Matulic-Adamic J, Warriner SL, Stockley PG,
Liljas L |
(2000) "Deletion
of a Single Hydrogen Bonding Atom from the MS2 RNA
Operator Leads to Dramatic Rearrangements at the
RNA-Coat Protein Interface." Nucleic Acids
Res., 28, 4611. doi: 10.1093/NAR/28.23.4611.
|
Ms2-RNA hairpin (4one -5) complex . SNAP output
|
|
2izm
|
virus-RNA |
X-ray (2.7 Å) |
Helgstrand C, Grahn E, Moss T, Stonehouse NJ, Tars K,
Stockley PG, Liljas L |
(2002) "Investigating
the Structural Basis of Purine Specificity in the
Structures of MS2 Coat Protein RNA Translational
Operator Complexes." Nucleic Acids Res.,
30, 2678. doi: 10.1093/NAR/GKF371.
|
Ms2-RNA hairpin (c-10) complex . SNAP output
|
|
2izn
|
virus-RNA |
X-ray (2.56 Å) |
Helgstrand C, Grahn E, Moss T, Stonehouse NJ, Tars K,
Stockley PG, Liljas L |
(2002) "Investigating
the Structural Basis of Purine Specificity in the
Structures of MS2 Coat Protein RNA Translational
Operator Complexes." Nucleic Acids Res.,
30, 2678. doi: 10.1093/NAR/GKF371.
|
Ms2-RNA hairpin (g-10) complex . SNAP output
|
|
2j0q
|
hydrolase |
X-ray (3.2 Å) |
Bono F, Ebert J, Lorentzen E, Conti E |
(2006) "The
Crystal Structure of the Exon Junction Complex Reveals
How It Maintains a Stable Grip on Mrna."
Cell(Cambridge,Mass.), 126,
713. doi: 10.1016/J.CELL.2006.08.006.
|
The crystal structure of the exon junction complex at
3.2 Å resolution . SNAP
output
|
|
2j0s
|
hydrolase |
X-ray (2.21 Å) |
Bono F, Ebert J, Lorentzen E, Conti E |
(2006) "The
Crystal Structure of the Exon Junction Complex Reveals
How It Mantains a Stable Grip on Mrna."
Cell(Cambridge,Mass.), 126,
713. doi: 10.1016/J.CELL.2006.08.006.
|
The crystal structure of the exon junction complex at
2.2 Å resolution . SNAP
output
|
|
2j28
|
ribosome |
cryo-EM (9.5 Å) |
Halic M, Blau M, Becker T, Mielke T, Pool MR, Wild K,
Sinning I, Beckmann R |
(2006) "Following
the Signal Sequence from Ribosomal Tunnel Exit to
Signal Recognition Particle." Nature,
444, 508-511. doi: 10.1038/nature05326.
|
Model of e. coli srp bound to 70s rncs . SNAP output
|
|
2j37
|
ribosome |
cryo-EM (8.7 Å) |
Halic M, Blau M, Becker T, Mielke T, Pool MR, Wild K,
Sinning I, Beckmann R |
(2006) "Following
the signal sequence from ribosomal tunnel exit to
signal recognition particle." Nature,
444, 507-511. doi: 10.1038/nature05326.
|
Model of mammalian srp bound to 80s rncs . SNAP output
|
|
2jlu
|
hydrolase-RNA |
X-ray (2.04 Å) |
Luo D, Xu T, Watson RP, Scherer-Becker D, Sampath A,
Jahnke W, Yeong SS, Wang CH, Lim SP, Strongin A,
Vasudevan SG, Lescar J |
(2008) "Insights
Into RNA Unwinding and ATP Hydrolysis by the Flavivirus
Ns3 Protein." Embo J.,
27, 3209. doi: 10.1038/EMBOJ.2008.232.
|
Dengue virus 4 ns3 helicase in complex with ssrna .
SNAP output
|
|
2jlv
|
hydrolase-RNA |
X-ray (1.9 Å) |
Luo DH, Xu T, Watson RP, Becker DS, Sampath A, Jahnke
W, Yeong SS, Wang CH, Lim SP, Strongin A, Vasudevan SG,
Lescar J |
(2008) "Insights
Into RNA Unwinding and ATP Hydrolysis by the Flavivirus
Ns3 Protein." Embo J.,
27, 3209. doi: 10.1038/EMBOJ.2008.232.
|
Dengue virus 4 ns3 helicase in complex with ssrna and
amppnp . SNAP output
|
|
2jlw
|
hydrolase-RNA |
X-ray (2.6 Å) |
Luo DH, Xu T, Watson RP, Becker DS, Sampath A, Jahnke
W, Yeong SS, Wang CH, Lim SP, Strongin A, Vasudevan SG,
Lescar J |
(2008) "Insights
Into RNA Unwinding and ATP Hydrolysis by the Flavivirus
Ns3 Protein." Embo J.,
27, 3209. doi: 10.1038/EMBOJ.2008.232.
|
Dengue virus 4 ns3 helicase in complex with ssrna2 .
SNAP output
|
|
2jlx
|
hydrolase-RNA |
X-ray (2.2 Å) |
Luo DH, Xu T, Watson RP, Scherer-Becker D, Sampath A,
Jahnke W, Yeong SS, Wang CH, Lim SP, Strongin A,
Vasudevan SG, Lescar J |
(2008) "Insights
Into RNA Unwinding and ATP Hydrolysis by the Flavivirus
Ns3 Protein." Embo J.,
27, 3209. doi: 10.1038/EMBOJ.2008.232.
|
Dengue virus 4 ns3 helicase in complex with ssrna and
adp-vanadate . SNAP
output
|
|
2jly
|
hydrolase-RNA |
X-ray (2.4 Å) |
Luo D, Xu T, Watson RP, Scherer-Becker D, Sampath A,
Jahnke W, Yeong SS, Wang CH, Lim SP, Strongin A,
Vasudevan SG, Lescar J |
(2008) "Insights
Into RNA Unwinding and ATP Hydrolysis by the Flavivirus
Ns3 Protein." Embo J.,
27, 3209. doi: 10.1038/EMBOJ.2008.232.
|
Dengue virus 4 ns3 helicase in complex with ssrna and
adp-phosphate . SNAP
output
|
|
2jlz
|
hydrolase-RNA |
X-ray (2.2 Å) |
Luo D, Xu T, Watson RP, Scherer-Becker D, Sampath A,
Jahnke W, Yeong SS, Wang CH, Lim SP, Strongin A,
Vasudevan SG, Lescar J |
(2008) "Insights
Into RNA Unwinding and ATP Hydrolysis by the Flavivirus
Ns3 Protein." Embo J.,
27, 3209. doi: 10.1038/EMBOJ.2008.232.
|
Dengue virus 4 ns3 helicase in complex with ssrna and
adp . SNAP output
|
|
2jpp
|
translation-RNA |
NMR |
Schubert M, Lapouge K, Duss O, Oberstrass FC,
Jelesarov I, Haas D, Allain FH-T |
(2007) "Molecular
basis of messenger RNA recognition by the specific
bacterial repressing clamp RsmA/CsrA."
Nat.Struct.Mol.Biol., 14,
807-813. doi: 10.1038/nsmb1285.
|
Structural basis of rsma-csra RNA recognition:
structure of rsme bound to the shine-dalgarno sequence
of hcna mrna . SNAP
output
|
|
2jq7
|
ribosome-antibiotic |
NMR |
Jonker HRA, Ilin S, Grimm SK, Woehnert J, Schwalbe
H |
(2007) "L11
Domain Rearrangement Upon Binding to RNA and
Thiostrepton Studied by NMR Spectroscopy."
Nucleic Acids Res., 35, 441.
doi: 10.1093/NAR/GKL1066.
|
Model for thiostrepton binding to the ribosomal l11-RNA
. SNAP output
|
|
2kdq
|
RNA binding protein-RNA |
NMR |
Davidson A, Leeper TC, Athanassiou Z,
Patora-Komisarska K, Karn J, Robinson JA, Varani G |
(2009) "Simultaneous
recognition of HIV-1 TAR RNA bulge and loop sequences
by cyclic peptide mimics of Tat protein."
Proc.Natl.Acad.Sci.USA, 106,
11931-11936. doi: 10.1073/pnas.0900629106.
|
Simultaneous recognition of hiv-1 tar RNA bulge and
loop sequences by cyclic peptide mimic of tat protein .
SNAP output
|
|
2kfy
|
RNA binding protein-RNA |
NMR |
Dominguez C, Fisette JF, Chabot B, Allain FH |
(2010) "Structural
basis of G-tract recognition and encaging by hnRNP F
quasi-RRMs." Nat.Struct.Mol.Biol.,
17, 853-861. doi: 10.1038/nsmb.1814.
|
NMR structure of the first qrrm of hnrnp f in complex
with agggau g-tract RNA . SNAP output
|
|
2kg0
|
RNA binding protein-RNA |
NMR |
Dominguez C, Fisette JF, Chabot B, Allain FH |
(2010) "Structural
basis of G-tract recognition and encaging by hnRNP F
quasi-RRMs." Nat.Struct.Mol.Biol.,
17, 853-861. doi: 10.1038/nsmb.1814.
|
Structure of the second qrrm domain of hnrnp f in
complex with a agggau g-tract RNA . SNAP output
|
|
2kg1
|
RNA binding protein-RNA |
NMR |
Dominguez C, Fisette JF, Chabot B, Allain FH |
(2010) "Structural
basis of G-tract recognition and encaging by hnRNP F
quasi-RRMs." Nat.Struct.Mol.Biol.,
17, 853-861. doi: 10.1038/nsmb.1814.
|
Structure of the third qrrm domain of hnrnp f in
complex with a agggau g-tract RNA . SNAP output
|
|
2kh9
|
splicing-RNA |
NMR |
Martin-Tumasz S, Reiter NJ, Brow DA, Butcher SE |
(2010) "Structure
and functional implications of a complex containing a
segment of U6 RNA bound by a domain of Prp24."
Rna, 16, 792-804. doi:
10.1261/rna.1913310.
|
Solution structure of yeast prp24-rrm2 bound to a
fragment of u6 RNA . SNAP output
|
|
2km8
|
RNA binding protein-RNA |
NMR |
Leeper TC, Qu X, Lu C, Moore C, Varani G |
(2010) "Novel
Protein-Protein Contacts Facilitate mRNA 3'-Processing
Signal Recognition by Rna15 and Hrp1."
J.Mol.Biol., 401, 334-349.
doi: 10.1016/j.jmb.2010.06.032.
|
Interdomain rrm packing contributes to RNA recognition
in the rna15, hrp1, anchor RNA 3' processing ternary
complex . SNAP
output
|
|
2kmj
|
RNA-peptide |
NMR |
Ferner J, Suhartono M, Breitung S, Jonker HRA, Hennig
M, Wohnert J, Gobel M, Schwalbe H |
(2009) "Structures
of HIV TAR RNA-ligand complexes reveal higher binding
stoichiometries." Chembiochem,
10, 1490-1494. doi: 10.1002/cbic.200900220.
|
High resolution NMR solution structure of a complex of
hiv-2 tar RNA and a synthetic tripeptide in a 1:2
stoichiometry . SNAP
output
|
|
2kx5
|
RNA binding protein-RNA |
NMR |
Davidson A, Patora-Komisarska K, Robinson JA, Varani
G |
(2011) "Essential
structural requirements for specific recognition of HIV
TAR RNA by peptide mimetics of Tat protein."
Nucleic Acids Res., 39,
248-256. doi: 10.1093/nar/gkq713.
|
Recognition of hiv tar RNA by peptide mimetic of tat
protein . SNAP
output
|
|
2kxn
|
RNA binding protein-RNA |
NMR |
Clery A, Jayne S, Benderska N, Dominguez C, Stamm S,
Allain FH |
(2011) "Molecular
basis of purine-rich RNA recognition by the human
SR-like protein Tra2-beta1."
Nat.Struct.Mol.Biol., 18,
443-450. doi: 10.1038/nsmb.2001.
|
NMR structure of human tra2beta1 rrm in complex with
aagaac RNA . SNAP
output
|
|
2l2k
|
hydrolase-RNA |
NMR |
Stefl R, Oberstrass FC, Hood JL, Jourdan M,
Zimmermann M, Skrisovska L, Maris C, Peng L, Hofr C,
Emeson RB, Allain FH |
(2010) "The
Solution Structure of the ADAR2 dsRBM-RNA Complex
Reveals a Sequence-Specific Readout of the Minor
Groove." Cell(Cambridge,Mass.),
143, 225-237. doi: 10.1016/j.cell.2010.09.026.
|
Solution NMR structure of the r-g stem loop RNA-adar2
dsrbm2 complex . SNAP
output
|
|
2l3c
|
hydrolase-RNA |
NMR |
Stefl R, Oberstrass FC, Hood JL, Jourdan M,
Zimmermann M, Skrisovska L, Maris C, Peng L, Hofr C,
Emeson RB, Allain FH |
(2010) "The
Solution Structure of the ADAR2 dsRBM-RNA Complex
Reveals a Sequence-Specific Readout of the Minor
Groove." Cell(Cambridge,Mass.),
143, 225-237. doi: 10.1016/j.cell.2010.09.026.
|
Solution structure of adar2 dsrbm1 bound to lsl RNA .
SNAP output
|
|
2l3j
|
hydrolase-RNA |
NMR |
Stefl R, Oberstrass FC, Hood JL, Jourdan M,
Zimmermann M, Skrisovska L, Maris C, Peng L, Hofr C,
Emeson RB, Allain FH |
(2010) "The
Solution Structure of the ADAR2 dsRBM-RNA Complex
Reveals a Sequence-Specific Readout of the Minor
Groove." Cell(Cambridge,Mass.),
143, 225-237. doi: 10.1016/j.cell.2010.09.026.
|
The solution structure of the adar2 dsrbm-RNA complex
reveals a sequence-specific read out of the minor
groove . SNAP output
|
|
2l41
|
RNA binding protein-RNA |
NMR |
Hobor F, Pergoli R, Kubicek K, Hrossova D, Bacikova
V, Zimmermann M, Pasulka J, Hofr C, Vanacova S, Stefl
R |
(2011) "Recognition
of transcription termination signal by the nuclear
polyadenylated RNA-binding (NAB) 3 protein."
J.Biol.Chem., 286, 3645-3657.
doi: 10.1074/jbc.M110.158774.
|
Nab3 rrm - ucuu complex . SNAP output
|
|
2l5d
|
RNA binding protein-RNA |
NMR |
Zeng L, Zhang Q, Yan K, Zhou MM |
(2011) "Structural
insights into piRNA recognition by the human PIWI-like
1 PAZ domain." Proteins,
79, 2004-2009. doi: 10.1002/prot.23003.
|
Solution structures of human piwi-like 1 paz domain
with ssrna (5'-pugaca) . SNAP output
|
|
2la5
|
RNA binding protein-RNA |
NMR |
Phan AT, Kuryavyi V, Darnell JC, Serganov A, Majumdar
A, Ilin S, Raslin T, Polonskaia A, Chen C, Clain D,
Darnell RB, Patel DJ |
(2011) "Structure-function
studies of FMRP RGG peptide recognition of an RNA
duplex-quadruplex junction."
Nat.Struct.Mol.Biol., 18,
796-804. doi: 10.1038/nsmb.2064.
|
RNA duplex-quadruplex junction complex with fmrp rgg
peptide . SNAP
output
|
|
2lbs
|
hydrolase-RNA |
NMR |
Wang Z, Hartman E, Roy K, Chanfreau G, Feigon J |
(2011) "Structure
of a Yeast RNase III dsRBD Complex with a Noncanonical
RNA Substrate Provides New Insights into Binding
Specificity of dsRBDs." Structure,
19, 999-1010. doi: 10.1016/j.str.2011.03.022.
|
Solution structure of double-stranded RNA binding
domain of s. cerevisiae rnase iii (rnt1p) in complex
with aagu tetraloop hairpin . SNAP output
|
|
2leb
|
RNA binding protein-RNA |
NMR |
Daubner GM, Clery A, Jayne S, Stevenin J, Allain
FH |
(2012) "A
syn-anti conformational difference allows SRSF2 to
recognize guanines and cytosines equally well."
Embo J., 31, 162-174. doi:
10.1038/emboj.2011.367.
|
Solution structure of human srsf2 (sc35) rrm in complex
with 5'-uccagu-3' . SNAP
output
|
|
2lec
|
RNA binding protein-RNA |
NMR |
Daubner GM, Clery A, Jayne S, Stevenin J, Allain
FH |
(2012) "A
syn-anti conformational difference allows SRSF2 to
recognize guanines and cytosines equally well."
Embo J., 31, 162-174. doi:
10.1038/emboj.2011.367.
|
Solution structure of human srsf2 (sc35) rrm in complex
with 5'-uggagu-3' . SNAP
output
|
|
2li8
|
transcription-RNA |
NMR |
Loughlin FE, Gebert LF, Towbin H, Brunschweiger A,
Hall J, Allain FH |
(2011) "Structural
basis of pre-let-7 miRNA recognition by the zinc
knuckles of pluripotency factor Lin28."
Nat.Struct.Mol.Biol., 19,
84-89. doi: 10.1038/nsmb.2202.
|
The solution structure of the lin28-znf domains bound
to aggagau of pre-let-7 mirna . SNAP output
|
|
2lup
|
RNA binding protein-RNA |
NMR |
Wang Z, Hartman E, Roy K, Chanfreau G, Feigon J |
(2011) "Structure
of a yeast RNase III dsRBD complex with a noncanonical
RNA substrate provides new insights into binding
specificity of dsRBDs." Structure,
19, 999-1010. doi: 10.1016/j.str.2011.03.022.
|
Rdc refined solution structure of double-stranded RNA
binding domain of s. cerevisiae rnase iii (rnt1p) in
complex with the terminal RNA hairpin of snr47
precursor . SNAP
output
|
|
2m8d
|
RNA binding protein-RNA |
NMR |
Clery A, Sinha R, Anczukow O, Corrionero A, Moursy A,
Daubner GM, Valcarcel J, Krainer AR, Allain FH |
(2013) "Isolated
pseudo-RNA-recognition motifs of SR proteins can
regulate splicing using a noncanonical mode of RNA
recognition." Proc.Natl.Acad.Sci.USA,
110, E2802-E2811. doi: 10.1073/pnas.1303445110.
|
Structure of srsf1 rrm2 in complex with the RNA
5'-ugaaggac-3' . SNAP
output
|
|
2mb0
|
splicing-RNA |
NMR |
Moursy A, Allain FH, Clery A |
(2014) "Characterization
of the RNA recognition mode of hnRNP G extends its role
in SMN2 splicing regulation." Nucleic Acids
Res., 42, 6659-6672. doi:
10.1093/nar/gku244.
|
Solution structure of hnrnp g rrm in complex with the
RNA 5'-aucaaa-3' . SNAP
output
|
|
2mf0
|
RNA binding protein-RNA |
NMR |
Duss O, Michel E, Yulikov M, Schubert M, Jeschke G,
Allain FH |
(2014) "Structural
basis of the non-coding RNA RsmZ acting as a protein
sponge." Nature, 509,
588-592. doi: 10.1038/nature13271.
|
Structural basis of the non-coding RNA rsmz acting as
protein sponge: conformer l of rsmz(1-72)-rsme(dimer)
1to3 complex . SNAP
output
|
|
2mf1
|
RNA binding protein-RNA |
NMR |
Duss O, Michel E, Yulikov M, Schubert M, Jeschke G,
Allain FH |
(2014) "Structural
basis of the non-coding RNA RsmZ acting as a protein
sponge." Nature, 509,
588-592. doi: 10.1038/nature13271.
|
Structural basis of the non-coding RNA rsmz acting as
protein sponge: conformer r of rsmz(1-72)-rsme(dimer)
1to3 complex . SNAP
output
|
|
2mfc
|
translation-RNA |
NMR |
Duss O, Michel E, Diarra Dit Konte N, Schubert M,
Allain FH |
(2014) "Molecular
basis for the wide range of affinity found in Csr/Rsm
protein-RNA recognition." Nucleic Acids
Res., 42, 5332-5346. doi:
10.1093/nar/gku141.
|
Csr-rsm protein-RNA recognition - a molecular affinity
ruler: rsmz(sl1)-rsme(dimer) 2:1 complex . SNAP output
|
|
2mfe
|
translation-RNA |
NMR |
Duss O, Michel E, Diarra Dit Konte N, Schubert M,
Allain FH |
(2014) "Molecular
basis for the wide range of affinity found in Csr/Rsm
protein-RNA recognition." Nucleic Acids
Res., 42, 5332-5346. doi:
10.1093/nar/gku141.
|
Csr-rsm protein-RNA recognition - a molecular affinity
ruler: rsmz(sl2)-rsme(dimer) 2:1 complex . SNAP output
|
|
2mff
|
translation-RNA |
NMR |
Duss O, Michel E, Diarra Dit Konte N, Schubert M,
Allain FH |
(2014) "Molecular
basis for the wide range of affinity found in Csr/Rsm
protein-RNA recognition." Nucleic Acids
Res., 42, 5332-5346. doi:
10.1093/nar/gku141.
|
Csr-rsm protein-RNA recognition - a molecular affinity
ruler: rsmz(sl3)-rsme(dimer) 2:1 complex . SNAP output
|
|
2mfg
|
translation-RNA |
NMR |
Duss O, Michel E, Diarra Dit Konte N, Schubert M,
Allain FH |
(2014) "Molecular
basis for the wide range of affinity found in Csr/Rsm
protein-RNA recognition." Nucleic Acids
Res., 42, 5332-5346. doi:
10.1093/nar/gku141.
|
Csr-rsm protein-RNA recognition - a molecular affinity
ruler: rsmz(sl4)-rsme(dimer) 2:1 complex . SNAP output
|
|
2mfh
|
translation-RNA |
NMR |
Duss O, Michel E, Diarra Dit Konte N, Schubert M,
Allain FH |
(2014) "Molecular
basis for the wide range of affinity found in Csr/Rsm
protein-RNA recognition." Nucleic Acids
Res., 42, 5332-5346. doi:
10.1093/nar/gku141.
|
Csr-rsm protein-RNA recognition - a molecular affinity
ruler: rsmz(36-44)-rsme(dimer) 2:1 complex . SNAP output
|
|
2mgz
|
RNA binding protein-RNA |
NMR |
Kuwasako K, Takahashi M, Unzai S, Tsuda K, Yoshikawa
S, He F, Kobayashi N, Guntert P, Shirouzu M, Ito T,
Tanaka A, Yokoyama S, Hagiwara M, Kuroyanagi H, Muto
Y |
(2014) "RBFOX
and SUP-12 sandwich a G base to cooperatively regulate
tissue-specific splicing."
Nat.Struct.Mol.Biol., 21,
778-786. doi: 10.1038/nsmb.2870.
|
Solution structure of rbfox family asd-1 rrm and sup-12
rrm in ternary complex with RNA . SNAP output
|
|
2mjh
|
RNA binding protein |
NMR |
Daubner GM, Brummer A, Tocchini C, Gerhardy S, Ciosk
R, Zavolan M, Allain FH |
(2014) "Structural
and functional implications of the QUA2 domain on RNA
recognition by GLD-1." Nucleic Acids Res.,
42, 8092-8105. doi: 10.1093/nar/gku445.
|
Solution structure of the gld-1 RNA-binding domain in
complex with RNA . SNAP
output
|
|
2mki
|
translation regulator-RNA |
NMR |
Afroz T, Skrisovska L, Belloc E, Guillen-Boixet J,
Mendez R, Allain FH-T |
(2014) "A fly
trap mechanism provides sequence-specific RNA
recognition by CPEB proteins." Genes Dev.,
28, 1498-1514. doi: 10.1101/gad.241133.114.
|
Solution structure of tandem rrm domains of cytoplasmic
polyadenylation element binding protein 4 (cpeb4) in
complex with RNA . SNAP
output
|
|
2mkk
|
translation regulator-RNA |
NMR |
Afroz T, Skrisovska L, Belloc E, Guillen-Boixet J,
Mendez R, Allain FH-T |
(2014) "A fly
trap mechanism provides sequence-specific RNA
recognition by CPEB proteins." Genes Dev.,
28, 1498-1514. doi: 10.1101/gad.241133.114.
|
Structural model of tandem rrm domains of cytoplasmic
polyadenylation element binding protein 1 (cpeb1) in
complex with RNA . SNAP
output
|
|
2mkn
|
RNA binding protein-RNA |
NMR |
Burge RG, Martinez-Yamout MA, Dyson HJ, Wright
PE |
(2014) "Structural
Characterization of Interactions between the
Double-Stranded RNA-Binding Zinc Finger Protein JAZ and
Nucleic Acids." Biochemistry,
53, 1495-1510. doi: 10.1021/bi401675h.
|
Structural characterization of interactions between the
double-stranded RNA-binding zinc finger protein jaz and
dsrna . SNAP output
|
|
2mqo
|
RNA binding protein-RNA |
NMR |
Blatter M, Allain F |
"Structural Investigation of hnRNP L bound to
RNA." |
Structural investigation of hnrnp l bound to RNA .
SNAP output
|
|
2mqp
|
RNA binding protein-RNA |
NMR |
Blatter M, Allain F |
"Structural Investigation of hnRNP L bound to
RNA." |
Structural investigation of hnrnp l bound to RNA .
SNAP output
|
|
2mqq
|
RNA binding protein-RNA |
NMR |
Blatter M, Allain F |
"Structural Investigation of hnRNP L bound to
RNA." |
Structural investigation of hnrnp l bound to RNA .
SNAP output
|
|
2mqv
|
viral protein-RNA |
NMR |
Miller SB, Yildiz FZ, Lo JA, Wang B, D'Souza VM |
(2014) "A
structure-based mechanism for tRNA and retroviral RNA
remodelling during primer annealing."
Nature, 515, 591-595. doi:
10.1038/nature13709.
|
Solution NMR structure of the u5-primer binding site
(u5-pbs) domain of murine leukemia virus RNA genome
bound to the retroviral nucleocapsid protein . SNAP output
|
|
2ms0
|
viral protein-RNA |
NMR |
Miller SB, Yildiz FZ, Lo JA, Wang B, D'Souza VM |
(2014) "A
structure-based mechanism for tRNA and retroviral RNA
remodelling during primer annealing."
Nature, 515, 591-595. doi:
10.1038/nature13709.
|
Solution NMR structure pf trnapro:mlv-nucleocapsid
(1:2) complex . SNAP
output
|
|
2ms1
|
viral protein-RNA |
NMR |
Miller SB, Yildiz FZ, Lo JA, Wang B, D'Souza VM |
(2014) "A
structure-based mechanism for tRNA and retroviral RNA
remodelling during primer annealing."
Nature, 515, 591-595. doi:
10.1038/nature13709.
|
Solution NMR structure of trnapro:mlv nucleocapsid
protein (1:1) complex . SNAP output
|
|
2mtv
|
RNA binding protein-RNA |
NMR |
Theler D, Dominguez C, Blatter M, Boudet J, Allain
FH |
(2014) "Solution
structure of the YTH domain in complex with
N6-methyladenosine RNA: a reader of methylated
RNA." Nucleic Acids Res.,
42, 13911-13919. doi: 10.1093/nar/gku1116.
|
Solution structure of the yth domain of yt521-b in
complex with n6-methyladenosine containing RNA .
SNAP output
|
|
2mxy
|
RNA binding protein-RNA |
NMR |
Cienikova Z, Damberger FF, Hall J, Allain FH, Maris
C |
(2014) "Structural
and mechanistic insights into poly(uridine) tract
recognition by the hnRNP C RNA recognition motif."
J.Am.Chem.Soc., 136,
14536-14544. doi: 10.1021/ja507690d.
|
Solution structure of hnrnp c rrm in complex with
5'-auuuuuc-3' RNA . SNAP
output
|
|
2mz1
|
RNA binding protein-RNA |
NMR |
Cienikova Z, Damberger FF, Hall J, Allain FH, Maris
C |
(2014) "Structural
and mechanistic insights into poly(uridine) tract
recognition by the hnRNP C RNA recognition motif."
J.Am.Chem.Soc., 136,
14536-14544. doi: 10.1021/ja507690d.
|
Solution structure of hnrnp c rrm in complex with
5'-uuuuc-3' RNA . SNAP
output
|
|
2n3o
|
RNA binding protein-RNA |
NMR |
Maris C, Jayne SF, Damberger FF, Ravindranathan S,
Allain FH-T |
"C-terminal helix folding upon pyrimidine-rich
hairpin binding to PTB RRM1. Implications for PTB
function in Encephalomyocarditis virus IRES
activity." |
Structure of ptb rrm1(41-163) bound to an RNA stemloop
containing a structured loop derived from viral
internal ribosomal entry site RNA . SNAP output
|
|
2n7c
|
RNA binding protein-RNA |
NMR |
Ganguly AK, Verma G, Bhavesh NS |
(2019) "The
N-terminal RNA Recognition Motif of PfSR1 Confers
Semi-specificity for Pyrimidines during RNA
Recognition." J. Mol. Biol.,
431, 498-510. doi: 10.1016/j.jmb.2018.11.020.
|
Solution structure of plasmodium falciparum sr1-rrm1 in
complex with acauca RNA . SNAP output
|
|
2n82
|
RNA binding protein-RNA |
NMR |
Chen Y, Zubovic L, Yang F, Godin K, Pavelitz T,
Castellanos J, Macchi P, Varani G |
(2016) "Rbfox
proteins regulate microRNA biogenesis by
sequence-specific binding to their precursors and
target downstream Dicer." Nucleic Acids
Res., 44, 4381-4395. doi:
10.1093/nar/gkw177.
|
Solution structure of the complex of microrna 20b
pre-element with rbfox rrm . SNAP output
|
|
2n8l
|
RNA binding protein-RNA |
NMR |
Nicastro G, Candel AM, Ramos A, Hollingworth D |
"Zipcode-binding-protein-1 KH3KH4(DD) domains in
complex with the RNA target GCACACCC." |
Zipcode-binding-protein-1 kh3kh4(dd) domains in complex
with the kh3 RNA target . SNAP output
|
|
2n8m
|
RNA binding protein-RNA |
NMR |
Nicastro G, Ramos A, Candel A, Hollingworth D |
"Zipcode-binding-protein-1 KH3(DD)KH4 domains in
complex with the RNA target UCGGACU." |
Zipcode-binding-protein-1 kh3(dd)kh4 domains in complex
with the kh4 RNA target . SNAP output
|
|
2noq
|
ribosome |
cryo-EM (7.3 Å) |
Schuler M, Connell SR, Lescoute A, Giesebrecht J,
Dabrowski M, Schroeer B, Mielke T, Penczek PA, Westhof E,
Spahn CM |
(2006) "Structure
of the ribosome-bound cricket paralysis virus IRES
RNA." Nat.Struct.Mol.Biol.,
13, 1092-1096. doi: 10.1038/nsmb1177.
|
Structure of ribosome-bound cricket paralysis virus
ires RNA . SNAP
output
|
|
2nre
|
isomerase-RNA |
X-ray (4.0 Å) |
Hur S, Stroud RM |
(2007) "How U38,
39, and 40 of Many tRNAs Become the Targets for
Pseudouridylation by TruA." Mol.Cell,
26, 189-203. doi: 10.1016/j.molcel.2007.02.027.
|
Crystal structure of pseudoudirinde synthase trua in
complex with leucyl trna . SNAP output
|
|
2nue
|
hydrolase-RNA |
X-ray (2.9 Å) |
Gan J, Shaw G, Tropea JE, Waugh DS, Court DL, Ji
X |
(2007) "A
stepwise model for double-stranded RNA processing by
ribonuclease III." Mol.Microbiol.,
67, 143-154. doi: 10.1111/j.1365-2958.2007.06032.x.
|
Crystal structure of rnase iii from aquifex aeolicus
complexed with ds-RNA at 2.9-angstrom resolution .
SNAP output
|
|
2nuf
|
hydrolase-RNA |
X-ray (2.5 Å) |
Gan J, Shaw G, Tropea JE, Waugh DS, Court DL, Ji
X |
(2007) "A
stepwise model for double-stranded RNA processing by
ribonuclease III." Mol.Microbiol.,
67, 143-154. doi: 10.1111/j.1365-2958.2007.06032.x.
|
Crystal structure of rnase iii from aquifex aeolicus
complexed with ds-RNA at 2.5-angstrom resolution .
SNAP output
|
|
2nug
|
hydrolase-RNA |
X-ray (1.7 Å) |
Gan J, Shaw G, Tropea JE, Waugh DS, Court DL, Ji
X |
(2007) "A
stepwise model for double-stranded RNA processing by
ribonuclease III." Mol.Microbiol.,
67, 143-154. doi: 10.1111/j.1365-2958.2007.06032.x.
|
Crystal structure of rnase iii from aquifex aeolicus
complexed with ds-RNA at 1.7-angstrom resolution .
SNAP output
|
|
2nz4
|
structural protein-RNA |
X-ray (2.498 Å) |
Cochrane JC, Lipchock SV, Strobel SA |
(2007) "Structural
Investigation of the GlmS Ribozyme Bound to Its
Catalytic Cofactor." Chem.Biol.,
14, 97-105. doi: 10.1016/j.chembiol.2006.12.005.
|
Structural investigation of the glms ribozyme bound to
its catalytic cofactor . SNAP output
|
|
2ogm
|
ribosome |
X-ray (3.5 Å) |
Davidovich C, Bashan A, Auerbach-Nevo T, Yaggie RD,
Gontarek RR, Yonath A |
(2007) "Induced-fit
tightens pleuromutilins binding to ribosomes and remote
interactions enable their selectivity."
Proc.Natl.Acad.Sci.Usa, 104,
4291-4296. doi: 10.1073/pnas.0700041104.
|
The crystal structure of the large ribosomal subunit
from deinococcus radiodurans complexed with the
pleuromutilin derivative sb-571519 . SNAP output
|
|
2oih
|
structural protein-RNA |
X-ray (2.4 Å) |
Ke A, Ding F, Batchelor JD, Doudna JA |
(2007) "Structural
roles of monovalent cations in the HDV ribozyme."
Structure, 15, 281-287. doi:
10.1016/j.str.2007.01.017.
|
Hepatitis delta virus gemonic ribozyme precursor with
c75u mutation and bound to monovalent cation tl+ .
SNAP output
|
|
2oj3
|
structural protein-RNA |
X-ray (2.9 Å) |
Ke A, Ding F, Batchelor JD, Doudna JA |
(2007) "Structural
roles of monovalent cations in the HDV ribozyme."
Structure, 15, 281-287. doi:
10.1016/j.str.2007.01.017.
|
Hepatitis delta virus ribozyme precursor structure,
with c75u mutation, bound to tl+ and cobalt hexammine
(co(nh3)63+) . SNAP
output
|
|
2om3
|
virus |
cryo-EM (4.4 Å) |
Sachse C, Chen JZ, Coureux PD, Stroupe ME, Fandrich
M, Grigorieff N |
(2007) "High-resolution
electron microscopy of helical specimens: a fresh look
at tobacco mosaic virus." J.Mol.Biol.,
371, 812-835. doi: 10.1016/j.jmb.2007.05.088.
|
High-resolution cryo-EM structure of tobacco mosaic
virus . SNAP output
|
|
2om7
|
ribosome |
cryo-EM (7.3 Å) |
Connell SR, Takemoto C, Wilson DN, Wang H, Murayama
K, Terada T, Shirouzu M, Rost M, Schuler M, Giesebrecht
J, Dabrowski M, Mielke T, Fucini P, Yokoyama S, Spahn
CM |
(2007) "Structural
basis for interaction of the ribosome with the switch
regions of GTP-bound elongation factors."
Mol.Cell, 25, 751-764. doi:
10.1016/j.molcel.2007.01.027.
|
Structural basis for interaction of the ribosome with
the switch regions of gtp-bound elongation factors .
SNAP output
|
|
2otj
|
ribosome |
X-ray (2.9 Å) |
Schroeder SJ, Blaha G, Tirado-Rives J, Steitz TA,
Moore PB |
(2007) "The
Structures of Antibiotics Bound to the E Site Region of
the 50 S Ribosomal Subunit of Haloarcula marismortui:
13-Deoxytedanolide and Girodazole."
J.Mol.Biol., 367, 1471-1479.
doi: 10.1016/j.jmb.2007.01.081.
|
13-deoxytedanolide bound to the large subunit of
haloarcula marismortui . SNAP output
|
|
2otl
|
ribosome |
X-ray (2.7 Å) |
Schroeder SJ, Blaha G, Tirado-Rives J, Steitz TA,
Moore PB |
(2007) "The
Structures of Antibiotics Bound to the E Site Region of
the 50 S Ribosomal Subunit of Haloarcula marismortui:
13-Deoxytedanolide and Girodazole."
J.Mol.Biol., 367, 1471-1479.
doi: 10.1016/j.jmb.2007.01.081.
|
Girodazole bound to the large subunit of haloarcula
marismortui . SNAP
output
|
|
2ozb
|
RNA binding protein-RNA |
X-ray (2.6 Å) |
Liu S, Li P, Dybkov O, Nottrott S, Hartmuth K,
Luhrmann R, Carlomagno T, Wahl MC |
(2007) "Binding
of the human Prp31 Nop domain to a composite
RNA-protein platform in U4 snRNP."
Science, 316, 115-120. doi:
10.1126/science.1137924.
|
Structure of a human prp31-15.5k-u4 snrna complex .
SNAP output
|
|
2pjp
|
translation-RNA |
X-ray (2.3 Å) |
Soler N, Fourmy D, Yoshizawa S |
(2007) "Structural
insight into a molecular switch in tandem winged-helix
motifs from elongation factor SelB."
J.Mol.Biol., 370, 728-741.
doi: 10.1016/j.jmb.2007.05.001.
|
Structure of the mrna-binding domain of elongation
factor selb from e.coli in complex with secis RNA .
SNAP output
|
|
2ply
|
translation-RNA |
X-ray (2.6 Å) |
Soler N, Fourmy D, Yoshizawa S |
(2007) "Structural
insight into a molecular switch in tandem winged-helix
motifs from elongation factor SelB."
J.Mol.Biol., 370, 728-741.
doi: 10.1016/j.jmb.2007.05.001.
|
Structure of the mrna binding fragment of elongation
factor selb in complex with secis RNA. . SNAP output
|
|
2po1
|
hydrolase-hydrolase-RNA |
X-ray (1.94 Å) |
Navarro MVAS, Oliveira CC, Zanchin NI, Guimaraes
BG |
(2008) "Insights
into the mechanism of progressive RNA degradation by
the archaeal exosome." J.Biol.Chem.,
283, 14120-14131. doi: 10.1074/jbc.M801005200.
|
Crystal structure of the p. abyssi exosome rnase ph
ring complexed with a single stranded 10-mer poly(a)
RNA . SNAP output
|
|
2pxb
|
signaling protein-RNA |
X-ray (2.5 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 2 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxd
|
signaling protein-RNA |
X-ray (2.0 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 1 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxe
|
signaling protein-RNA |
X-ray (2.0 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 4 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxf
|
signaling protein-RNA |
X-ray (2.0 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 5 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxk
|
signaling protein-RNA |
X-ray (2.5 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 8 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxl
|
signaling protein-RNA |
X-ray (2.5 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 9 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxp
|
signaling protein-RNA |
X-ray (2.5 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 13 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxq
|
signaling protein-RNA |
X-ray (2.5 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 14 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxt
|
signaling protein-RNA |
X-ray (2.5 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 15 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxu
|
signaling protein-RNA |
X-ray (2.5 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 16 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2pxv
|
signaling protein-RNA |
X-ray (2.0 Å) |
Keel AY, Rambo RP, Batey RT, Kieft JS |
(2007) "A
General Strategy to Solve the Phase Problem in RNA
Crystallography." Structure,
15, 761-772. doi: 10.1016/j.str.2007.06.003.
|
Variant 6 of ribonucleoprotein core of the e. coli
signal recognition particle . SNAP output
|
|
2py9
|
RNA and DNA binding protein-RNA |
X-ray (2.56 Å) |
Du Z, Lee JK, Fenn S, Tjhen R, Stroud RM, James
TL |
(2007) "X-ray
crystallographic and NMR studies of protein-protein and
protein-nucleic acid interactions involving the KH
domains from human poly(C)-binding protein-2."
Rna, 13, 1043-1051. doi:
10.1261/rna.410107.
|
Protein-RNA interaction involving kh1 domain from human
poly(c)-binding protein-2 . SNAP output
|
|
2q66
|
transferase-RNA |
X-ray (1.8 Å) |
Balbo PB, Bohm A |
(2007) "Mechanism
of poly(A) polymerase: structure of the
enzyme-MgATP-RNA ternary complex and kinetic
analysis." Structure, 15,
1117-1131. doi: 10.1016/j.str.2007.07.010.
|
Structure of yeast poly(a) polymerase with atp and
oligo(a) . SNAP
output
|
|
2qa4
|
ribosome |
X-ray (3.0 Å) |
Kavran JM, Steitz TA |
(2007) "Structure
of the base of the L7/L12 stalk of the Haloarcula
marismortui large ribosomal subunit: Analysis of L11
movements." J.Mol.Biol.,
371, 1047-1059. doi: 10.1016/j.jmb.2007.05.091.
|
A more complete structure of the the l7-l12 stalk of
the haloarcula marismortui 50s large ribosomal subunit
. SNAP output
|
|
2qex
|
ribosome |
X-ray (2.9 Å) |
Schroeder SJ, Blaha G, Moore PB |
(2007) "Negamycin
binds to the wall of the nascent chain exit tunnel of
the 50S ribosomal subunit." Antimicrob.Agents
Chemother., 51, 4462-4465. doi:
10.1128/AAC.00455-07.
|
Negamycin binds to the wall of the nascent chain exit
tunnel of the 50s ribosomal subunit . SNAP output
|
|
2qqp
|
virus |
X-ray (3.8 Å) |
Speir JA, Taylor DJ, Natarajan P, Pringle FM, Ball
LA, Johnson JE |
(2010) "Evolution
in action: N and C termini of subunits in related T = 4
viruses exchange roles as molecular switches."
Structure, 18, 700-709. doi:
10.1016/j.str.2010.03.010.
|
Crystal structure of authentic providence virus .
SNAP output
|
|
2qux
|
structural protein-RNA |
X-ray (2.44 Å) |
Chao JA, Patskovsky Y, Almo SC, Singer RH |
(2008) "Structural
basis for the coevolution of a viral RNA-protein
complex." Nat.Struct.Mol.Biol.,
15, 103-105. doi: 10.1038/nsmb1327.
|
Pp7 coat protein dimer in complex with RNA hairpin .
SNAP output
|
|
2r7r
|
transferase-RNA |
X-ray (2.6 Å) |
Lu X, McDonald SM, Tortorici MA, Tao YJ, Vasquez-Del
Carpio R, Nibert ML, Patton JT, Harrison SC |
(2008) "Mechanism
for coordinated RNA packaging and genome replication by
rotavirus polymerase VP1." Structure,
16, 1678-1688. doi: 10.1016/j.str.2008.09.006.
|
Crystal structure of rotavirus sa11 vp1-RNA (ugugacc)
complex . SNAP
output
|
|
2r7s
|
transferase-RNA |
X-ray (3.24 Å) |
Lu X, McDonald SM, Tortorici MA, Tao YJ, Vasquez-Del
Carpio R, Nibert ML, Patton JT, Harrison SC |
(2008) "Mechanism
for coordinated RNA packaging and genome replication by
rotavirus polymerase VP1." Structure,
16, 1678-1688. doi: 10.1016/j.str.2008.09.006.
|
Crystal structure of rotavirus sa11 vp1 - RNA (ugugcc)
complex . SNAP
output
|
|
2r7t
|
transferase-RNA |
X-ray (3.0 Å) |
Lu X, McDonald SM, Tortorici MA, Tao YJ, Vasquez-Del
Carpio R, Nibert ML, Patton JT, Harrison SC |
(2008) "Mechanism
for coordinated RNA packaging and genome replication by
rotavirus polymerase VP1." Structure,
16, 1678-1688. doi: 10.1016/j.str.2008.09.006.
|
Crystal structure of rotavirus sa11 vp1-RNA (ugugaacc)
complex . SNAP
output
|
|
2r7u
|
transferase-RNA |
X-ray (3.1 Å) |
Lu X, McDonald SM, Tortorici MA, Tao YJ, Vasquez-Del
Carpio R, Nibert ML, Patton JT, Harrison SC |
(2008) "Mechanism
for coordinated RNA packaging and genome replication by
rotavirus polymerase VP1." Structure,
16, 1678-1688. doi: 10.1016/j.str.2008.09.006.
|
Crystal structure of rotavirus sa11 vp1-RNA (aaaagcc)
complex . SNAP
output
|
|
2r7v
|
transferase-RNA |
X-ray (2.8 Å) |
Lu X, McDonald SM, Tortorici MA, Tao YJ, Vasquez-Del
Carpio R, Nibert ML, Patton JT, Harrison SC |
(2008) "Mechanism
for coordinated RNA packaging and genome replication by
rotavirus polymerase VP1." Structure,
16, 1678-1688. doi: 10.1016/j.str.2008.09.006.
|
Crystal structure of rotavirus sa11 vp1-RNA (ggcuuu)
complex . SNAP
output
|
|
2r7w
|
transferase-RNA |
X-ray (2.6 Å) |
Lu X, McDonald SM, Tortorici MA, Tao YJ, Vasquez-Del
Carpio R, Nibert ML, Patton JT, Harrison SC |
(2008) "Mechanism
for coordinated RNA packaging and genome replication by
rotavirus polymerase VP1." Structure,
16, 1678-1688. doi: 10.1016/j.str.2008.09.006.
|
Crystal structure of rotavirus sa11 vp1-RNA
(ugugacc)-mrna 5'-cap (m7gpppg) complex . SNAP output
|
|
2r7x
|
transferase-RNA |
X-ray (2.8 Å) |
Lu X, McDonald SM, Tortorici MA, Tao YJ, Vasquez-Del
Carpio R, Nibert ML, Patton JT, Harrison SC |
(2008) "Mechanism
for coordinated RNA packaging and genome replication by
rotavirus polymerase VP1." Structure,
16, 1678-1688. doi: 10.1016/j.str.2008.09.006.
|
Crystal structure of rotavirus sa11 vp1-RNA
(ugugacc)-gtp complex . SNAP output
|
|
2r8s
|
immune system-RNA |
X-ray (1.95 Å) |
Ye JD, Tereshko V, Frederiksen JK, Koide A, Fellouse
FA, Sidhu SS, Koide S, Kossiakoff AA, Piccirilli JA |
(2008) "Synthetic
antibodies for specific recognition and crystallization
of structured RNA."
Proc.Natl.Acad.Sci.Usa, 105,
82-87. doi: 10.1073/pnas.0709082105.
|
High resolution structure of a specific synthetic fab
bound to p4-p6 RNA ribozyme domain . SNAP output
|
|
2r92
|
transferase-RNA |
X-ray (3.8 Å) |
Lehmann E, Brueckner F, Cramer P |
(2007) "Molecular
basis of RNA-dependent RNA polymerase II activity."
Nature, 450, 445-449. doi:
10.1038/nature06290.
|
Elongation complex of RNA polymerase ii with artificial
rdrp scaffold . SNAP
output
|
|
2r93
|
transferase-RNA |
X-ray (4.0 Å) |
Lehmann E, Brueckner F, Cramer P |
(2007) "Molecular
basis of RNA-dependent RNA polymerase II activity."
Nature, 450, 445-449. doi:
10.1038/nature06290.
|
Elongation complex of RNA polymerase ii with a
hepatitis delta virus-derived RNA stem loop . SNAP output
|
|
2rd2
|
ligase-RNA |
X-ray (2.6 Å) |
Bullock TL, Rodriguez-Hernandez A, Corigliano EM,
Perona JJ |
(2008) "A
rationally engineered misacylating aminoacyl-tRNA
synthetase." Proc.Natl.Acad.Sci.Usa,
105, 7428-7433. doi: 10.1073/pnas.0711812105.
|
Glutaminyl-trna synthetase mutant c229r with bound
analog 5'-o-[n-(l-glutaminyl)-sulfamoyl]adenosine .
SNAP output
|
|
2re8
|
ligase-RNA |
X-ray (2.6 Å) |
Bullock TL, Rodriguez-Hernandez A, Corigliano EM,
Perona JJ |
(2008) "A
rationally engineered misacylating aminoacyl-tRNA
synthetase." Proc.Natl.Acad.Sci.Usa,
105, 7428-7433. doi: 10.1073/pnas.0711812105.
|
Glutaminyl-trna synthetase mutant c229r with bound
analog 5'-o-[n-(l-glutamyl)-sulfamoyl]adenosine .
SNAP output
|
|
2rfk
|
isomerase-RNA |
X-ray (2.87 Å) |
Liang B, Xue S, Terns RM, Terns MP, Li H |
(2007) "Substrate
RNA positioning in the archaeal H/ACA ribonucleoprotein
complex." Nat.Struct.Mol.Biol.,
14, 1189-1195. doi: 10.1038/nsmb1336.
|
Substrate RNA positioning in the archaeal h-aca
ribonucleoprotein complex . SNAP output
|
|
2rkj
|
ligase-RNA |
X-ray (4.5 Å) |
Paukstelis PJ, Chen JH, Chase E, Lambowitz AM, Golden
BL |
(2008) "Structure
of a tyrosyl-tRNA synthetase splicing factor bound to a
group I intron RNA." Nature,
451, 94-97. doi: 10.1038/nature06413.
|
Cocrystal structure of a tyrosyl-trna synthetase
splicing factor with a group i intron RNA . SNAP output
|
|
2rqc
|
transcription-RNA |
NMR |
Tsuda K, Kuwasako K, Takahashi M, Someya T, Inoue M,
Terada T, Kobayashi N, Shirouzu M, Kigawa T, Tanaka A,
Sugano S, Guntert P, Muto Y, Yokoyama S |
(2009) "Structural
basis for the sequence-specific RNA-recognition
mechanism of human CUG-BP1 RRM3." Nucleic Acids
Res., 37, 5151-5166. doi:
10.1093/nar/gkp546.
|
Solution structure of RNA-binding domain 3 of cugbp1 in
complex with RNA (ug)3 . SNAP output
|
|
2rra
|
RNA binding protein-RNA |
NMR |
Tsuda K, Someya T, Kuwasako K, Takahashi M, He F,
Unzai S, Inoue M, Harada T, Watanabe S, Terada T,
Kobayashi N, Shirouzu M, Kigawa T, Tanaka A, Sugano S,
Guntert P, Yokoyama S, Muto Y |
(2011) "Structural
basis for the dual RNA-recognition modes of human
Tra2-beta RRM." Nucleic Acids Res.,
39, 1538-1553. doi: 10.1093/nar/gkq854.
|
Solution structure of RNA binding domain in human tra2
beta protein in complex with RNA (gaagaa) . SNAP output
|
|
2rs2
|
RNA binding protein-RNA |
NMR |
Ohyama T, Nagata T, Tsuda K, Kobayashi N, Imai T,
Okano H, Yamazaki T, Katahira M |
(2011) "Structure
of Musashi1 in a complex with target RNA: the role of
aromatic stacking interactions." Nucleic Acids
Res. doi: 10.1093/nar/gkr1139.
|
1h, 13c, and 15n chemical shift assignments for
musashi1 rbd1:r(guagu) complex . SNAP output
|
|
2rsk
|
membrane protein-RNA |
NMR |
Mashima T, Nishikawa F, Kamatari YO, Fujiwara H,
Saimura M, Nagata T, Kodaki T, Nishikawa S, Kuwata K,
Katahira M |
(2013) "Anti-prion
activity of an RNA aptamer and its structural
basis." Nucleic Acids Res.,
41, 1355-1362. doi: 10.1093/nar/gks1132.
|
RNA aptamer against prion protein in complex with the
partial binding peptide . SNAP output
|
|
2ru3
|
RNA binding protein-RNA |
NMR |
Kuwasako K, Takahashi M, Unzai S, Tsuda K, Yoshikawa
S, He F, Kobayashi N, Guntert P, Shirouzu M, Ito T,
Tanaka A, Yokoyama S, Hagiwara M, Kuroyanagi H, Muto
Y |
(2014) "RBFOX
and SUP-12 sandwich a G base to cooperatively regulate
tissue-specific splicing."
Nat.Struct.Mol.Biol., 21,
778-786. doi: 10.1038/nsmb.2870.
|
Solution structure of c.elegans sup-12 rrm in complex
with RNA . SNAP
output
|
|
2ru7
|
membrane protein-RNA |
NMR |
Hayashi T, Oshima H, Mashima T, Nagata T, Katahira M,
Kinoshita M |
(2014) "Binding
of an RNA aptamer and a partial peptide of a prion
protein: crucial importance of water entropy in
molecular recognition." Nucleic Acids
Res., 42, 6861-6875. doi:
10.1093/nar/gku382.
|
Refined structure of RNA aptamer in complex with the
partial binding peptide of prion protein . SNAP output
|
|
2tmv
|
virus-RNA |
fiber diffraction |
Namba K, Pattanayek R, Stubbs G |
(1989) "Visualization
of protein-nucleic acid interactions in a virus.
Refined structure of intact tobacco mosaic virus at 2.9
A resolution by X-ray fiber diffraction."
J.Mol.Biol., 208, 307-325.
doi: 10.1016/0022-2836(89)90391-4.
|
Visualization of protein-nucleic acid interactions in a
virus. refined structure of intact tobacco mosaic virus
at 2.9 angstroms resolution by x-ray fiber diffraction
. SNAP output
|
|
2uu9
|
ribosome |
X-ray (3.1 Å) |
Weixlbaumer A, Murphy 4th FV, Dziergowska A,
Malkiewicz A, Vendeix FA, Agris PF, Ramakrishnan V |
(2007) "Mechanism
for expanding the decoding capacity of transfer RNAs by
modification of uridines." Nat. Struct. Mol.
Biol., 14, 498-502. doi: 10.1038/nsmb1242.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a valine-asl with cmo5u in
position 34 bound to an mrna with a gug-codon in the
a-site and paromomycin. . SNAP output
|
|
2uua
|
ribosome |
X-ray (2.9 Å) |
Weixlbaumer A, Murphy 4th FV, Dziergowska A,
Malkiewicz A, Vendeix FA, Agris PF, Ramakrishnan V |
(2007) "Mechanism
for expanding the decoding capacity of transfer RNAs by
modification of uridines." Nat. Struct. Mol.
Biol., 14, 498-502. doi: 10.1038/nsmb1242.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a valine-asl with cmo5u in
position 34 bound to an mrna with a guc-codon in the
a-site and paromomycin. . SNAP output
|
|
2uub
|
ribosome |
X-ray (2.8 Å) |
Weixlbaumer A, Murphy FV, Dziergowska A, Malkiewicz
A, Vendeix FAP, Agris PF, Ramakrishnan V |
(2007) "Mechanism
for Expanding the Decoding Capacity of Transfer Rnas by
Modification of Uridines."
Nat.Struct.Mol.Biol., 14,
498. doi: 10.1038/NSMB1242.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a valine-asl with cmo5u in
position 34 bound to an mrna with a guu-codon in the
a-site and paromomycin. . SNAP output
|
|
2uuc
|
ribosome |
X-ray (3.1 Å) |
Weixlbaumer A, Murphy FV, Dziergowska A, Malkiewicz
A, Vendeix FA, Agris PF, Ramakrishnan V |
(2007) "Mechanism
for expanding the decoding capacity of transfer RNAs by
modification of uridines." Nat. Struct. Mol.
Biol., 14, 498-502. doi: 10.1038/nsmb1242.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a valine-asl with cmo5u in
position 34 bound to an mrna with a gua-codon in the
a-site and paromomycin. . SNAP output
|
|
2uwm
|
translation |
X-ray (2.31 Å) |
Ose T, Soler N, Rasubala L, Kuroki K, Kohda D, Fourmy
D, Yoshizawa S, Maenaka K |
(2007) "Structural
Basis for Dynamic Interdomain Movement and RNA
Recognition of the Selenocysteine-Specific Elongation
Factor Selb." Structure,
15, 577. doi: 10.1016/J.STR.2007.03.007.
|
C-terminal domain(wh2-wh4) of elongation factor selb in
complex with secis RNA . SNAP output
|
|
2uxb
|
ribosome |
X-ray (3.1 Å) |
Dunham CM, Selmer M, Phelps SS, Kelley AC, Suzuki T,
Joseph S, Ramakrishnan V |
(2007) "Structures
of tRNAs with an expanded anticodon loop in the
decoding center of the 30S ribosomal subunit."
RNA, 13, 817-823. doi:
10.1261/rna.367307.
|
Crystal structure of an extended trna anticodon stem
loop in complex with its cognate mrna gggu in the
context of the thermus thermophilus 30s subunit. .
SNAP output
|
|
2uxc
|
ribosome |
X-ray (2.9 Å) |
Dunham CM, Selmer M, Phelps SS, Kelley AC, Suzuki T,
Joseph S, Ramakrishnan V |
(2007) "Structures
of Trnas with an Expanded Anticodon Loop in the
Decoding Center of the 30S Ribosomal Subunit."
RNA, 13, 817. doi: 10.1261/RNA.367307.
|
Crystal structure of an extended trna anticodon stem
loop in complex with its cognate mrna ucgu in the
context of the thermus thermophilus 30s subunit. .
SNAP output
|
|
2uxd
|
ribosome |
X-ray (3.2 Å) |
Dunham CM, Selmer M, Phelps SS, Kelley AC, Suzuki T,
Joseph S, Ramakrishnan V |
(2007) "Structures
of Trnas with an Expanded Anticodon Loop in the
Decoding Center of the 30S Ribosomal Subunit."
RNA, 13, 817. doi: 10.1261/RNA.367307.
|
Crystal structure of an extended trna anticodon stem
loop in complex with its cognate mrna cggg in the
context of the thermus thermophilus 30s subunit. .
SNAP output
|
|
2v0g
|
ligase |
X-ray (3.5 Å) |
Rock F, Mao W, Yaremchuk A, Tukalo M, Crepin T, Zhou
H, Zhang Y, Hernandez V, Akama T, Baker S, Plattner J,
Shapiro L, Martinis SA, Benkovic SJ, Cusack S, Alley
MRK |
(2007) "An
Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase
by Trapping tRNA in the Editing Site."
Science, 316, 1759. doi:
10.1126/SCIENCE.1142189.
|
Leucyl-trna synthetase from thermus thermophilus
complexed with a trna(leu) transcript with
5-fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole
(an2690) forming an adduct to the ribose of adenosine-
76 in the enzyme editing site. . SNAP output
|
|
2v3c
|
signaling protein |
X-ray (2.5 Å) |
Hainzl T, Huang S, Sauer-Eriksson AE |
(2007) "Interaction
of Signal-Recognition Particle 54 Gtpase Domain and
Signal-Recognition Particle RNA in the Free
Signal-Recognition Particle."
Proc.Natl.Acad.Sci.USA, 104,
14911. doi: 10.1073/PNAS.0702467104.
|
Crystal structure of the srp54-srp19-7s.s srp RNA
complex of m. jannaschii . SNAP output
|
|
2vnu
|
hydrolase-RNA |
X-ray (2.3 Å) |
Lorentzen E, Basquin J, Tomecki R, Dziembowski A,
Conti E |
(2008) "Structure
of the Active Subunit of the Yeast Exosome Core, Rrp44:
Diverse Modes of Substrate Recruitment in the Rnase II
Nuclease Family." Mol.Cell,
29, 717. doi: 10.1016/J.MOLCEL.2008.02.018.
|
Crystal structure of sc rrp44 . SNAP output
|
|
2vod
|
RNA binding protein |
X-ray (2.1 Å) |
Kotik-Kogan O, Valentine ER, Sanfelice D, Conte MR,
Curry S |
(2008) "Structural
Analysis Reveals Conformational Plasticity in the
Recognition of RNA 3' Ends by the Human La
Protein." Structure, 16,
852. doi: 10.1016/J.STR.2008.02.021.
|
Crystal structure of n-terminal domains of human la
protein complexed with RNA oligomer auauuuu . SNAP output
|
|
2von
|
RNA binding protein |
X-ray (2.1 Å) |
Kotik-Kogan O, Valentine ER, Sanfelice D, Conte MR,
Curry S |
(2008) "Structural
Analysis Reveals Conformational Plasticity in the
Recognition of RNA 3' Ends by the Human La
Protein." Structure, 16,
852. doi: 10.1016/J.STR.2008.02.021.
|
Crystal structure of n-terminal domains of human la
protein complexed with RNA oligomer auaauuu . SNAP output
|
|
2voo
|
RNA binding protein |
X-ray (1.8 Å) |
Kotik-Kogan O, Valentine ER, Sanfelice D, Conte MR,
Curry S |
(2008) "Structural
Analysis Reveals Conformational Plasticity in the
Recognition of RNA 3' Ends by the Human La
Protein." Structure, 16,
852. doi: 10.1016/J.STR.2008.02.021.
|
Crystal structure of n-terminal domains of human la
protein complexed with RNA oligomer uuuuuuuu . SNAP output
|
|
2vop
|
RNA binding protein |
X-ray (2.8 Å) |
Kotik-Kogan O, Valentine ER, Sanfelice D, Conte MR,
Curry S |
(2008) "Structural
Analysis Reveals Conformational Plasticity in the
Recognition of RNA 3' Ends by the Human La
Protein." Structure, 16,
852. doi: 10.1016/J.STR.2008.02.021.
|
Crystal structure of n-terminal domains of human la
protein complexed with RNA oligomer auuuu . SNAP output
|
|
2vpl
|
translation |
X-ray (2.3 Å) |
Tishchenko S, Kljashtorny V, Kostareva O, Nevskaya N,
Nikulin A, Gulak P, Piendl W, Garber M, Nikonov S |
(2008) "Domain
II of Thermus thermophilus ribosomal protein L1 hinders
recognition of its mRNA." J. Mol. Biol.,
383, 301-305. doi: 10.1016/j.jmb.2008.08.058.
|
The structure of the complex between the first domain
of l1 protein from thermus thermophilus and mrna from
methanococcus jannaschii . SNAP output
|
|
2vqe
|
ribosome |
X-ray (2.5 Å) |
Kurata S, Weixlbaumer A, Ohtsuki T, Shimazaki T, Wada
T, Kirino Y, Takai K, Watanabe K, Ramakrishnan V, Suzuki
T |
(2008) "Modified
Uridines with C5-Methylene Substituents at the First
Position of the tRNA Anticodon Stabilize U.G Wobble
Pairing During Decoding." J.Biol.Chem.,
283, 18801. doi: 10.1074/JBC.M800233200.
|
Modified uridines with c5-methylene substituents at the
first position of the trna anticodon stabilize u-g
wobble pairing during decoding . SNAP output
|
|
2vqf
|
ribosome |
X-ray (2.9 Å) |
Kurata S, Weixlbaumer A, Ohtsuki T, Shimazaki T, Wada
T, Kirino Y, Takai K, Watanabe K, Ramakrishnan V, Suzuki
T |
(2008) "Modified
Uridines with C5-Methylene Substituents at the First
Position of the tRNA Anticodon Stabilize U.G Wobble
Pairing During Decoding." J.Biol.Chem.,
283, 18801. doi: 10.1074/JBC.M800233200.
|
Modified uridines with c5-methylene substituents at the
first position of the trna anticodon stabilize u-g
wobble pairing during decoding . SNAP output
|
|
2vrt
|
hydrolase |
X-ray (3.5 Å) |
Koslover DJ, Callaghan AJ, Marcaida MJ, Garman EF,
Martick M, Scott WG, Luisi BF |
(2008) "The
Crystal Structure of the Escherichia Coli Rnase E
Apoprotein and a Mechanism for RNA Degradation."
Structure, 16, 1238. doi:
10.1016/J.STR.2008.04.017.
|
Crystal structure of e. coli rnase e possessing m1 RNA
fragments - catalytic domain . SNAP output
|
|
2w2h
|
RNA binding protein |
X-ray (3.25 Å) |
Anand K, Schulte A, Vogel-Bachmayr K, Scheffzek K,
Geyer M |
(2008) "Structural
Insights Into the Cyclin T1-Tat-Tar RNA Transcription
Activation Complex from Eiav."
Nat.Struct.Mol.Biol., 15,
1287. doi: 10.1038/NSMB.1513.
|
Structural basis of transcription activation by the
cyclin t1-tat-tar RNA complex from eiav . SNAP output
|
|
2wj8
|
RNA binding protein-RNA |
X-ray (3.29 Å) |
Tawar RG, Duquerroy S, Vonrhein C, Varela PF,
Damier-Piolle L, Castagne N, Maclellan K, Bedouelle H,
Bricogne G, Bhella D, Eleouet J, Rey FA |
(2009) "Crystal
Structure of a Nucleocapsid-Like Nucleoprotein-RNA
Complex of Respiratory Syncytial Virus."
Science, 326, 1279. doi:
10.1126/SCIENCE.1177634.
|
Respiratory syncitial virus ribonucleoprotein .
SNAP output
|
|
2ww9
|
ribosome |
cryo-EM (8.6 Å) |
Becker T, Bhushan S, Jarasch A, Armache JP, Funes S,
Jossinet F, Gumbart J, Mielke T, Berninghausen O,
Schulten K, Westhof E, Gilmore R, Mandon E, Beckmann
R |
(2009) "Structure
of Monomeric Yeast and Mammalian Sec61 Complexes
Interacting with the Translating Ribosome."
Science, 326, 1369. doi:
10.1126/SCIENCE.1178535.
|
cryo-EM structure of the active yeast ssh1 complex
bound to the yeast 80s ribosome . SNAP output
|
|
2wwa
|
ribosome |
cryo-EM (8.9 Å) |
Becker T, Bhushan S, Jarasch A, Armache JP, Funes S,
Jossinet F, Gumbart J, Mielke T, Berninghausen O,
Schulten K, Westhof E, Gilmore R, Mandon E, Beckmann
R |
(2009) "Structure
of Monomeric Yeast and Mammalian Sec61 Complexes
Interacting with the Translating Ribosome."
Science, 326, 1369. doi:
10.1126/SCIENCE.1178535.
|
cryo-EM structure of idle yeast ssh1 complex bound to
the yeast 80s ribosome . SNAP output
|
|
2wwb
|
ribosome |
cryo-EM (6.48 Å) |
Becker T, Bhushan S, Jarasch A, Armache JP, Funes S,
Jossinet F, Gumbart J, Mielke T, Berninghausen O,
Schulten K, Westhof E, Gilmore R, Mandon E, Beckmann
R |
(2009) "Structure
of Monomeric Yeast and Mammalian Sec61 Complexes
Interacting with the Translating Ribosome."
Science, 326, 1369. doi:
10.1126/SCIENCE.1178535.
|
cryo-EM structure of the mammalian sec61 complex bound
to the actively translating wheat germ 80s ribosome .
SNAP output
|
|
2wyy
|
virus |
cryo-EM (10.6 Å) |
Ge P, Tsao J, Schein S, Green TJ, Luo M, Zhou ZH |
(2010) "Cryo-Em
Model of the Bullet-Shaped Vesicular Stomatitis
Virus." Science, 327,
689. doi: 10.1126/SCIENCE.1181766.
|
Cryoem model of the vesicular stomatitis virus .
SNAP output
|
|
2x1f
|
transcription-RNA |
X-ray (1.6 Å) |
Pancevac C, Goldstone DC, Ramos A, Taylor IA |
(2010) "Structure
of the RNA15 Rrm-RNA Complex Reveals the Molecular
Basis of Gu Specificity in Transcriptional 3-End
Processing Factors." Nucleic Acids Res.,
38, 3119. doi: 10.1093/NAR/GKQ002.
|
Structure of rna15 rrm with bound RNA (gu) . SNAP output
|
|
2x7n
|
ribosomal protein-RNA |
cryo-EM (11.8 Å) |
Gartmann M, Blau M, Armache J-P, Mielke T, Topf M,
Beckmann R |
(2010) "Mechanism
of Eif6-Mediated Inhibition of Ribosomal Subunit
Joining." J.Biol.Chem.,
285, 14848. doi: 10.1074/JBC.C109.096057.
|
Mechanism of eif6s anti-association activity . SNAP output
|
|
2xb2
|
hydrolase |
X-ray (3.4 Å) |
Buchwald G, Ebert J, Basquin C, Sauliere J,
Jayachandran U, Bono F, Le Hir H, Conti E |
(2010) "Insights
Into the Recruitment of the Nmd Machinery from the
Crystal Structure of a Core Ejc-Upf3B Complex."
Proc.Natl.Acad.Sci.USA, 107,
10050. doi: 10.1073/PNAS.1000993107.
|
Crystal structure of the core
mago-y14-eif4aiii-barentsz-upf3b assembly shows how the
ejc is bridged to the nmd machinery . SNAP output
|
|
2xbm
|
RNA binding protein |
X-ray (2.9 Å) |
Yap LJ, Luo DH, Chung KY, Lim SP, Bodenreider C,
Noble C, Shi PY, Lescar J |
(2010) "Crystal
Structure of the Dengue Virus Methyltransferase Bound
to a 5'-Capped Octameric RNA." Plos One,
5, 12836. doi: 10.1371/JOURNAL.PONE.0012836.
|
Crystal structure of the dengue virus methyltransferase
bound to a 5'- capped octameric RNA . SNAP output
|
|
2xc7
|
RNA binding protein |
NMR |
Mourao A, Varrot A, Mackereth CD, Cusack S, Sattler
M |
(2010) "Structure
and RNA Recognition by the Snrna and Snorna Transport
Factor Phax." RNA, 16,
1205. doi: 10.1261/RNA.2009910.
|
Solution structure of phax-rbd in complex with ssrna .
SNAP output
|
|
2xd0
|
toxin-RNA |
X-ray (3.0 Å) |
Blower TR, Pei XY, Short FL, Fineran PC, Humphreys
DP, Luisi BF, Salmond GP |
(2011) "A
processed noncoding RNA regulates an altruistic
bacterial antiviral system." Nat. Struct. Mol.
Biol., 18, 185-190. doi: 10.1038/nsmb.1981.
|
A processed non-coding RNA regulates a bacterial
antiviral system . SNAP
output
|
|
2xdb
|
toxin-RNA |
X-ray (2.55 Å) |
Blower TR, Pei XY, Short FL, Fineran PC, Humphreys
DP, Luisi BF, Salmond GPC |
(2011) "A
Processed Noncoding RNA Regulates an Altruistic
Bacterial Antiviral System."
Nat.Struct.Mol.Biol., 18,
185. doi: 10.1038/NSMB.1981.
|
A processed non-coding RNA regulates a bacterial
antiviral system . SNAP
output
|
|
2xdd
|
toxin-RNA |
X-ray (3.2 Å) |
Fineran PC, Blower TR, Foulds IJ, Humphreys DP,
Lilley KS, Salmond GPC |
(2009) "The
Phage Abortive Infection System, Toxin, Functions as a
Protein-RNA Toxin-Antitoxin Pair."
Proc.Natl.Acad.Sci.USA, 106,
894. doi: 10.1073/PNAS.0808832106.
|
A processed non-coding RNA regulates a bacterial
antiviral system . SNAP
output
|
|
2xea
|
virus |
cryo-EM (4.6 Å) |
Clare DK, Orlova EV |
(2010) "4.6 A
Cryo-Em Reconstruction of Tobacco Mosaic Virus from
Images Recorded at 300 Kev on a 4Kx4K Ccd Camera."
J.Struct.Biol., 171, 303.
doi: 10.1016/J.JSB.2010.06.011.
|
4.6 angstrom cryo-EM reconstruction of tobacco mosaic
virus from images recorded at 300 kev on a 4kx4k ccd
camera . SNAP output
|
|
2xfm
|
RNA-protein |
NMR |
Simon B, Kirkpatrick JP, Eckhardt S, Reuter M, Rocha
EA, Andrade-Navarro MA, Sehr P, Pillai RS, Carlomagno
T |
(2011) "Recognition
of 2'-O-Methylated 3'-End of Pirna by the Paz Domain of
a Piwi Protein." Structure,
19, 172. doi: 10.1016/J.STR.2010.11.015.
|
Complex structure of the miwi paz domain bound to
methylated single stranded RNA . SNAP output
|
|
2xgj
|
hydrolase-RNA |
X-ray (2.9 Å) |
Weir JR, Bonneau F, Hentschel J, Conti E |
(2010) "Structural
Analysis Reveals the Characteristic Features of Mtr4, a
Dexh Helicase Involved in Nuclear RNA Processing and
Surveillance." Proc.Natl.Acad.Sci.USA,
107, 12139. doi: 10.1073/PNAS.1004953107.
|
Structure of mtr4, a dexh helicase involved in nuclear
RNA processing and surveillance . SNAP output
|
|
2xkv
|
protein transport |
cryo-EM (13.5 Å) |
Estrozi LF, Boehringer D, Shan S-O, Ban N,
Schaffitzel C |
(2011) "Cryo-Em
Structure of the E. Coli Translating Ribosome in
Complex with Srp and its Receptor."
Nat.Struct.Mol.Biol., 18, 88.
doi: 10.1038/NSMB.1952.
|
Atomic model of the srp-ftsy early conformation .
SNAP output
|
|
2xpj
|
virus |
X-ray (3.4 Å) |
Sagurthi SR, Rajaram V, Savithri HS, Murthy MRN |
"Crystal Structure of Natural Bottom Component of
Phmv." |
Crystal structure of physalis mottle virus with intact
ordered RNA . SNAP
output
|
|
2xs2
|
RNA binding protein-RNA |
X-ray (1.35 Å) |
Jenkins HT, Malkova B, Edwards TA |
(2011) "Kinked
beta-strands mediate high-affinity recognition of mRNA
targets by the germ-cell regulator DAZL." Proc.
Natl. Acad. Sci. U.S.A., 108,
18266-18271. doi: 10.1073/pnas.1105211108.
|
Crystal structure of the rrm domain of mouse deleted in
azoospermia-like in complex with RNA, uuguucuu .
SNAP output
|
|
2xs5
|
RNA binding protein-RNA |
X-ray (1.6 Å) |
Jenkins HT, Edwards TA |
(2011) "Kinked
Beta-Strands Mediate High-Affinity Recognition of Mrna
Targets by the Germ-Cell Regulator Dazl."
Proc.Natl.Acad.Sci.USA, 108,
18266. doi: 10.1073/PNAS.1105211108.
|
Crystal structure of the rrm domain of mouse deleted in
azoospermia- like in complex with mvh RNA, uguuc .
SNAP output
|
|
2xs7
|
RNA binding protein-RNA |
X-ray (1.45 Å) |
Jenkins HT, Edwards TA |
(2011) "Kinked
Beta-Strands Mediate High-Affinity Recognition of Mrna
Targets by the Germ-Cell Regulator Dazl."
Proc.Natl.Acad.Sci.USA, 108,
18266. doi: 10.1073/PNAS.1105211108.
|
Crystal structure of the rrm domain of mouse deleted in
azoospermia- like in complex with sycp3 RNA, uuguuu .
SNAP output
|
|
2xxa
|
protein transport |
X-ray (3.94 Å) |
Ataide SF, Schmitz N, Shen K, Ke A, Shan S, Doudna
JA, Ban N |
(2011) "The
Crystal Structure of the Signal Recognition Particle in
Complex with its Receptor." Science,
331, 881. doi: 10.1126/SCIENCE.1196473.
|
The crystal structure of the signal recognition
particle (srp) in complex with its receptor(sr) .
SNAP output
|
|
2xzl
|
hydrolase-RNA |
X-ray (2.4 Å) |
Chakrabarti S, Jayachandran U, Bonneau F, Fiorini F,
Basquin C, Domcke S, Le Hir H, Conti E |
(2011) "Molecular
Mechanisms for the RNA-Dependent ATPase Activity of
Upf1 and its Regulation by Upf2."
Mol.Cell, 41, 693. doi:
10.1016/J.MOLCEL.2011.02.010.
|
Upf1-RNA complex . SNAP
output
|
|
2xzo
|
hydrolase-RNA |
X-ray (2.395 Å) |
Chakrabarti S, Jayachandran U, Bonneau F, Fiorini F,
Basquin C, Domcke S, Le Hir H, Conti E |
(2011) "Molecular
Mechanisms for the RNA-Dependent ATPase Activity of
Upf1 and its Regulation by Upf2."
Mol.Cell, 41, 693. doi:
10.1016/J.MOLCEL.2011.02.010.
|
Upf1 helicase - RNA complex . SNAP output
|
|
2y8w
|
hydrolase-RNA |
X-ray (1.8 Å) |
Sashital DG, Jinek M, Doudna JA |
(2011) "An
RNA-Induced Conformational Change Required for Crispr
RNA Cleavage by the Endoribonuclease Cse3."
Nat.Struct.Mol.Biol., 18,
680. doi: 10.1038/NSMB.2043.
|
Structure of crispr endoribonuclease cse3 bound to 20
nt RNA . SNAP output
|
|
2y8y
|
hydrolase-RNA |
X-ray (1.44 Å) |
Sashital DG, Jinek M, Doudna JA |
(2011) "An
RNA-Induced Conformational Change Required for Crispr
RNA Cleavage by the Endoribonuclease Cse3."
Nat.Struct.Mol.Biol., 18,
680. doi: 10.1038/NSMB.2043.
|
Structure b of crispr endoribonuclease cse3 bound to 19
nt RNA . SNAP output
|
|
2yh1
|
transcription |
NMR |
Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K,
Gasch A, Rybin V, Valcarcel J, Sattler M |
(2011) "Multi-Domain
Conformational Selection Underlies Pre-Mrna Splicing
Regulation by U2Af." Nature,
475, 408. doi: 10.1038/NATURE10171.
|
Model of human u2af65 tandem rrm1 and rrm2 domains with
eight-site uridine binding . SNAP output
|
|
2yhm
|
viral protein-RNA |
X-ray (3.6 Å) |
El Omari K, Dhaliwal B, Ren J, Abrescia NGA, Lockyer
M, Powell KL, Hawkins AR, Stammers DK |
(2011) "Structures
of Respiratory Syncytial Virus Nucleocapsid Protein
from Two Crystal Forms: Details of Potential Packing
Interactions in the Native Helical Form." Acta
Crystallogr.,Sect.F, 67, 1179.
doi: 10.1107/S1744309111029228.
|
Structure of respiratory syncytial virus nucleocapsid
protein, p212121 crystal form . SNAP output
|
|
2yjy
|
RNA binding protein-RNA |
X-ray (2.598 Å) |
Dong S, Wang Y, Cassidy-Amstutz C, Lu G, Bigler R,
Jezyk MR, Li C, Hall TM, Wang Z |
(2011) "Specific
and Modular Binding Code for Cytosine Recognition in
Pumilio/Fbf (Puf) RNA-Binding Domains."
J.Biol.Chem., 286, 26732.
doi: 10.1074/JBC.M111.244889.
|
A specific and modular binding code for cytosine
recognition in puf domains . SNAP output
|
|
2ykg
|
hydrolase |
X-ray (2.5 Å) |
Luo D, Ding SC, Vela A, Kohlway A, Lindenbach BD,
Pyle AM |
(2011) "Structural
Insights Into RNA Recognition by Rig-I."
Cell(Cambridge,Mass.), 147,
409. doi: 10.1016/J.CELL.2011.09.023.
|
Structural insights into RNA recognition by rig-i .
SNAP output
|
|
2ykr
|
ribosome-hydrolase |
cryo-EM (9.8 Å) |
Guo Q, Yuan Y, Xu Y, Feng B, Liu L, Chen K, Sun M,
Yang Z, Lei J, Gao N |
(2011) "Structural
Basis for the Function of a Small Gtpase Rsga on the
30S Ribosomal Subunit Maturation Revealed by
Cryoelectron Microscopy."
Proc.Natl.Acad.Sci.USA, 108,
13100. doi: 10.1073/PNAS.1104645108.
|
30s ribosomal subunit with rsga bound in the presence
of gmppnp . SNAP
output
|
|
2zh1
|
transferase-RNA |
X-ray (2.8 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminida . SNAP output
|
|
2zh2
|
transferase-RNA |
X-ray (2.66 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminidac . SNAP output
|
|
2zh3
|
transferase-RNA |
X-ray (2.5 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminidca . SNAP output
|
|
2zh4
|
transferase-RNA |
X-ray (2.65 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminidcg . SNAP output
|
|
2zh5
|
transferase-RNA |
X-ray (2.6 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminidcu . SNAP output
|
|
2zh6
|
transferase-RNA |
X-ray (2.5 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminidcu and atp .
SNAP output
|
|
2zh7
|
transferase-RNA |
X-ray (3.0 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminidg . SNAP output
|
|
2zh8
|
transferase-RNA |
X-ray (2.65 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminidgc . SNAP output
|
|
2zh9
|
transferase-RNA |
X-ray (2.9 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminidu . SNAP output
|
|
2zha
|
transferase-RNA |
X-ray (2.95 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminidu and ctp .
SNAP output
|
|
2zhb
|
transferase-RNA |
X-ray (3.05 Å) |
Toh Y, Numata T, Watanabe K, Takeshita D, Nureki O,
Tomita K |
(2008) "Molecular
basis for maintenance of fidelity during the CCA-adding
reaction by a CCA-adding enzyme." Embo J.,
27, 1944-1952. doi: 10.1038/emboj.2008.124.
|
Complex structure of afcca with trnaminiduc . SNAP output
|
|
2zi0
|
gene regulation-RNA |
X-ray (2.82 Å) |
Chen H-Y, Yang J, Lin C, Yuan YA |
(2008) "Structural
basis for RNA-silencing suppression by Tomato aspermy
virus protein 2b." Embo Rep.,
9, 754-760. doi: 10.1038/embor.2008.118.
|
Crystal structure of tav2b-sirna complex . SNAP output
|
|
2zjp
|
ribosome-antibiotic |
X-ray (3.7 Å) |
Harms JM, Wilson DN, Schluenzen F, Connell SR,
Stachelhaus T, Zaborowska Z, Spahn CM, Fucini P |
(2008) "Translational
Regulation Via L11: Molecular Switches on the Ribosome
Turned on and Off by Thiostrepton and Micrococcin."
Mol.Cell, 30, 26. doi:
10.1016/J.MOLCEL.2008.01.009.
|
Thiopeptide antibiotic nosiheptide bound to the large
ribosomal subunit of deinococcus radiodurans . SNAP output
|
|
2zjq
|
ribosome |
X-ray (3.3 Å) |
Harms JM, Wilson DN, Schluenzen F, Connell SR,
Stachelhaus T, Zaborowska Z, Spahn CM, Fucini P |
(2008) "Translational
regulation via L11: molecular switches on the ribosome
turned on and off by thiostrepton and micrococcin."
Mol.Cell, 30, 26-38. doi:
10.1016/j.molcel.2008.01.009.
|
Interaction of l7 with l11 induced by microccocin
binding to the deinococcus radiodurans 50s subunit .
SNAP output
|
|
2zjr
|
ribosome |
X-ray (2.91 Å) |
Harms JM, Wilson DN, Schluenzen F, Connell SR,
Stachelhaus T, Zaborowska Z, Spahn CM, Fucini P |
(2008) "Translational
regulation via L11: molecular switches on the ribosome
turned on and off by thiostrepton and micrococcin."
Mol.Cell, 30, 26-38. doi:
10.1016/j.molcel.2008.01.009.
|
Refined native structure of the large ribosomal subunit
(50s) from deinococcus radiodurans . SNAP output
|
|
2zko
|
RNA binding protein-RNA |
X-ray (1.7 Å) |
Cheng A, Wong SM, Yuan YA |
(2009) "Structural
basis for dsRNA recognition by NS1 protein of influenza
A virus." Cell Res., 19,
187-195. doi: 10.1038/cr.2008.288.
|
Structural basis for dsrna recognition by ns1 protein
of human influenza virus a . SNAP output
|
|
2zm5
|
transferase-RNA |
X-ray (2.55 Å) |
Chimnaronk S, Forouhar F, Sakai J, Yao M, Tron CM,
Atta M, Fontecave M, Hunt JF, Tanaka I |
(2009) "Snapshots
of dynamics in synthesizing N(6)-isopentenyladenosine
at the tRNA anticodon." Biochemistry,
48, 5057-5065. doi: 10.1021/bi900337d.
|
Crystal structure of trna modification enzyme miaa in
the complex with trna(phe) . SNAP output
|
|
2zm6
|
ribosome |
X-ray (3.3 Å) |
Kaminishi T, Wang H, Kawazoe M, Ishii R,
Hanawa-Suetsugu K, Nomura M, Takemoto C, Shirouzu M,
Paola F, Yokoyama S |
"Crystal structure of the Thermus thermophilus 30S
ribosomal subunit." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit . SNAP
output
|
|
2zni
|
ligase-RNA |
X-ray (3.1 Å) |
Nozawa K, O'Donoghue P, Gundllapalli S, Araiso Y,
Ishitani R, Umehara T, Soll D, Nureki O |
(2009) "Pyrrolysyl-tRNA
synthetase-tRNA(Pyl) structure reveals the molecular
basis of orthogonality." Nature,
457, 1163-1167. doi: 10.1038/nature07611.
|
Crystal structure of pyrrolysyl-trna
synthetase-trna(pyl) complex from desulfitobacterium
hafniense . SNAP
output
|
|
2zue
|
ligase-RNA |
X-ray (2.0 Å) |
Konno M, Sumida T, Uchikawa E, Mori Y, Yanagisawa T,
Sekine S, Yokoyama S |
(2009) "Modeling
of tRNA-assisted mechanism of Arg activation based on a
structure of Arg-tRNA synthetase, tRNA, and an ATP
analog (ANP)." Febs J.,
276, 4763-4779. doi: 10.1111/j.1742-4658.2009.07178.x.
|
Crystal structure of pyrococcus horikoshii arginyl-trna
synthetase complexed with trna(arg) and an atp analog
(anp) . SNAP output
|
|
2zuf
|
ligase-RNA |
X-ray (2.3 Å) |
Konno M, Sumida T, Uchikawa E, Mori Y, Yanagisawa T,
Sekine S, Yokoyama S |
(2009) "Modeling
of tRNA-assisted mechanism of Arg activation based on a
structure of Arg-tRNA synthetase, tRNA, and an ATP
analog (ANP)." Febs J.,
276, 4763-4779. doi: 10.1111/j.1742-4658.2009.07178.x.
|
Crystal structure of pyrococcus horikoshii arginyl-trna
synthetase complexed with trna(arg) . SNAP output
|
|
2zxu
|
transferase-RNA |
X-ray (2.75 Å) |
Chimnaronk S, Forouhar F, Sakai J, Yao M, Tron CM,
Atta M, Fontecave M, Hunt JF, Tanaka I |
(2009) "Snapshots
of dynamics in synthesizing N(6)-isopentenyladenosine
at the tRNA anticodon." Biochemistry,
48, 5057-5065. doi: 10.1021/bi900337d.
|
Crystal structure of trna modification enzyme miaa in
the complex with trna(phe) and dmaspp . SNAP output
|
|
2zzm
|
transferase-RNA |
X-ray (2.65 Å) |
Goto-Ito S, Ito T, Kuratani M, Bessho Y, Yokoyama
S |
(2009) "Tertiary
structure checkpoint at anticodon loop modification in
tRNA functional maturation."
Nat.Struct.Mol.Biol., 16,
1109-1115. doi: 10.1038/nsmb.1653.
|
The complex structure of atrm5 and trnaleu . SNAP output
|
|
2zzn
|
transferase-RNA |
X-ray (2.95 Å) |
Goto-Ito S, Ito T, Kuratani M, Bessho Y, Yokoyama
S |
(2009) "Tertiary
structure checkpoint at anticodon loop modification in
tRNA functional maturation."
Nat.Struct.Mol.Biol., 16,
1109-1115. doi: 10.1038/nsmb.1653.
|
The complex structure of atrm5 and trnacys . SNAP output
|
|
3a2k
|
ligase-RNA |
X-ray (3.65 Å) |
Nakanishi K, Bonnefond L, Kimura S, Suzuki T,
Ishitani R, Nureki O |
(2009) "Structural
basis for translational fidelity ensured by transfer
RNA lysidine synthetase." Nature,
461, 1144-1148. doi: 10.1038/nature08474.
|
Crystal structure of tils complexed with trna .
SNAP output
|
|
3a6p
|
protein transport-nuclear protein-RNA |
X-ray (2.92 Å) |
Okada C, Yamashita E, Lee SJ, Shibata S, Katahira J,
Nakagawa A, Yoneda Y, Tsukihara T |
(2009) "A
high-resolution structure of the pre-microRNA nuclear
export machinery." Science,
326, 1275-1279. doi: 10.1126/science.1178705.
|
Crystal structure of exportin-5:rangtp:pre-mirna
complex . SNAP
output
|
|
3adb
|
transferase-RNA |
X-ray (2.8 Å) |
Chiba S, Itoh Y, Sekine S, Yokoyama S |
(2010) "Structural
Basis for the Major Role of O-Phosphoseryl-tRNA Kinase
in the UGA-Specific Encoding of Selenocysteine."
Mol.Cell, 39, 410-420. doi:
10.1016/j.molcel.2010.07.018.
|
Crystal structure of o-phosphoseryl-trna kinase
complexed with selenocysteine trna and amppnp (crystal
type 1) . SNAP
output
|
|
3adc
|
transferase-RNA |
X-ray (2.9 Å) |
Chiba S, Itoh Y, Sekine S, Yokoyama S |
(2010) "Structural
Basis for the Major Role of O-Phosphoseryl-tRNA Kinase
in the UGA-Specific Encoding of Selenocysteine."
Mol.Cell, 39, 410-420. doi:
10.1016/j.molcel.2010.07.018.
|
Crystal structure of o-phosphoseryl-trna kinase
complexed with selenocysteine trna and amppnp (crystal
type 2) . SNAP
output
|
|
3add
|
transferase-RNA |
X-ray (2.4 Å) |
Chiba S, Itoh Y, Sekine S, Yokoyama S |
(2010) "Structural
Basis for the Major Role of O-Phosphoseryl-tRNA Kinase
in the UGA-Specific Encoding of Selenocysteine."
Mol.Cell, 39, 410-420. doi:
10.1016/j.molcel.2010.07.018.
|
Crystal structure of o-phosphoseryl-trna kinase
complexed with selenocysteine trna and amppnp (crystal
type 3) . SNAP
output
|
|
3adi
|
gene regulation-RNA |
X-ray (3.2 Å) |
Yang SW, Chen HY, Yang J, Machida S, Chua NH, Yuan
YA |
(2010) "Structure
of arabidopsis HYPONASTIC LEAVES1 and its molecular
implications for miRNA processing."
Structure, 18, 594-605. doi:
10.1016/j.str.2010.02.006.
|
Structure of arabidopsis hyl1 and its molecular
implications for mirna processing . SNAP output
|
|
3adl
|
gene regulation-RNA |
X-ray (2.2 Å) |
Yang SW, Chen HY, Yang J, Machida S, Chua NH, Yuan
YA |
(2010) "Structure
of arabidopsis HYPONASTIC LEAVES1 and its molecular
implications for miRNA processing."
Structure, 18, 594-605. doi:
10.1016/j.str.2010.02.006.
|
Structure of trbp2 and its molecule implications for
mirna processing . SNAP
output
|
|
3aev
|
translation-RNA binding protein-RNA |
X-ray (2.8 Å) |
Jia MZ, Horita S, Nagata K, Tanokura M |
(2010) "An
archaeal Dim2-like protein, aDim2p, forms a ternary
complex with a/eIF2 alpha and the 3' end fragment of
16S rRNA." J.Mol.Biol.,
398, 774-785. doi: 10.1016/j.jmb.2010.03.055.
|
Crystal structure of a-eif2alpha-adim2p-rrna complex
from pyrococcus horikoshii ot3 . SNAP output
|
|
3af6
|
hydrolase-RNA |
X-ray (2.6 Å) |
Nishida Y, Ishikawa H, Baba S, Nakagawa N, Kuramitsu
S, Masui R |
(2010) "Crystal
structure of an archaeal cleavage and polyadenylation
specificity factor subunit from Pyrococcus
horikoshii." Proteins,
78, 2395-2398. doi: 10.1002/prot.22748.
|
The crystal structure of an archaeal cpsf subunit,
ph1404 from pyrococcus horikoshii complexed with
RNA-analog . SNAP
output
|
|
3agv
|
immune system-RNA |
X-ray (2.15 Å) |
Nomura Y, Sugiyama S, Sakamoto T, Miyakawa S, Adachi
H, Takano K, Murakami S, Inoue T, Mori Y, Nakamura Y,
Matsumura H |
(2010) "Conformational
plasticity of RNA for target recognition as revealed by
the 2.15 A crystal structure of a human IgG-aptamer
complex." Nucleic Acids Res.,
38, 7822-7829. doi: 10.1093/nar/gkq615.
|
Crystal structure of a human igg-aptamer complex .
SNAP output
|
|
3ahu
|
translation-RNA |
X-ray (2.2 Å) |
Someya T, Baba S, Fujimoto M, Kumasaka T, Kawai G,
Nakamura K |
"Crystal structure of YmaH (Hfq) from Bacillus
subtilis in complex with an RNA aptamer." |
Crystal structure of ymah (hfq) from bacillus subtilis
in complex with an RNA aptamer. . SNAP output
|
|
3akz
|
ligase-RNA |
X-ray (2.9 Å) |
Ito T, Yokoyama S |
(2010) "Two
enzymes bound to one transfer RNA assume alternative
conformations for consecutive reactions."
Nature, 467, 612-616. doi:
10.1038/nature09411.
|
Crystal structure of thermotoga maritima
nondiscriminating glutamyl-trna synthetase in complex
with trnagln and a glutamyl-amp analog . SNAP output
|
|
3al0
|
ligase-RNA |
X-ray (3.368 Å) |
Ito T, Yokoyama S |
(2010) "Two
enzymes bound to one transfer RNA assume alternative
conformations for consecutive reactions."
Nature, 467, 612-616. doi:
10.1038/nature09411.
|
Crystal structure of the glutamine transamidosome from
thermotoga maritima in the glutamylation state. .
SNAP output
|
|
3am1
|
transferase-RNA |
X-ray (2.4 Å) |
Sherrer RL, Araiso Y, Aldag C, Ishitani R, Ho JML,
Soll D, Nureki O |
(2011) "C-terminal
domain of archaeal O-phosphoseryl-tRNA kinase displays
large-scale motion to bind the 7-bp D-stem of archaeal
tRNA(Sec)." Nucleic Acids Res.,
39, 1034-1041. doi: 10.1093/nar/gkq845.
|
Crystal structure of o-phosphoseryl-trna kinase
complexed with anticodon-stem-loop truncated trna(sec)
. SNAP output
|
|
3amt
|
RNA binding protein-RNA |
X-ray (2.9 Å) |
Osawa T, Kimura S, Terasaka N, Inanaga H, Suzuki T,
Numata T |
(2011) "Structural
basis of tRNA agmatinylation essential for AUA codon
decoding." Nat.Struct.Mol.Biol.,
18, 1275-1280. doi: 10.1038/nsmb.2144.
|
Crystal structure of the tias-trna(ile2)-atp complex .
SNAP output
|
|
3amu
|
RNA binding protein-RNA |
X-ray (3.1 Å) |
Osawa T, Kimura S, Terasaka N, Inanaga H, Suzuki T,
Numata T |
(2011) "Structural
basis of tRNA agmatinylation essential for AUA codon
decoding." Nat.Struct.Mol.Biol.,
18, 1275-1280. doi: 10.1038/nsmb.2144.
|
Crystal structure of the
tias-trna(ile2)-ampcpp-agmatine complex . SNAP output
|
|
3avt
|
translation, transferase-RNA |
X-ray (2.607 Å) |
Takeshita D, Tomita K |
(2012) "Molecular
basis for RNA polymerization by Q beta replicase."
Nat.Struct.Mol.Biol., 19,
229-237. doi: 10.1038/nsmb.2204.
|
Structure of viral RNA polymerase complex 1 . SNAP output
|
|
3avu
|
translation, transferase-RNA |
X-ray (2.907 Å) |
Takeshita D, Tomita K |
(2012) "Molecular
basis for RNA polymerization by Q beta replicase."
Nat.Struct.Mol.Biol., 19,
229-237. doi: 10.1038/nsmb.2204.
|
Structure of viral RNA polymerase complex 2 . SNAP output
|
|
3avv
|
translation, transferase-RNA |
X-ray (3.119 Å) |
Takeshita D, Tomita K |
(2012) "Molecular
basis for RNA polymerization by Q beta replicase."
Nat.Struct.Mol.Biol., 19,
229-237. doi: 10.1038/nsmb.2204.
|
Structure of viral RNA polymerase complex 3 . SNAP output
|
|
3avw
|
translation, transferase-RNA |
X-ray (2.602 Å) |
Takeshita D, Tomita K |
(2012) "Molecular
basis for RNA polymerization by Q beta replicase."
Nat.Struct.Mol.Biol., 19,
229-237. doi: 10.1038/nsmb.2204.
|
Structure of viral RNA polymerase complex 4 . SNAP output
|
|
3avx
|
translation, transferase-RNA |
X-ray (2.406 Å) |
Takeshita D, Tomita K |
(2012) "Molecular
basis for RNA polymerization by Q beta replicase."
Nat.Struct.Mol.Biol., 19,
229-237. doi: 10.1038/nsmb.2204.
|
Structure of viral RNA polymerase complex 5 . SNAP output
|
|
3avy
|
translation, transferase-RNA |
X-ray (2.616 Å) |
Takeshita D, Tomita K |
(2012) "Molecular
basis for RNA polymerization by Q beta replicase."
Nat.Struct.Mol.Biol., 19,
229-237. doi: 10.1038/nsmb.2204.
|
Structure of viral RNA polymerase complex 6 . SNAP output
|
|
3b0u
|
oxidoreductase-RNA |
X-ray (1.948 Å) |
Yu F, Tanaka Y, Yamashita K, Suzuki T, Nakamura A,
Hirano N, Suzuki T, Yao M, Tanaka I |
(2011) "Molecular
basis of dihydrouridine formation on tRNA."
Proc.Natl.Acad.Sci.USA, 108,
19593-19598. doi: 10.1073/pnas.1112352108.
|
Trna-dihydrouridine synthase from thermus thermophilus
in complex with trna fragment . SNAP output
|
|
3b0v
|
oxidoreductase-RNA |
X-ray (3.51 Å) |
Yu F, Tanaka Y, Yamashita K, Suzuki T, Nakamura A,
Hirano N, Suzuki T, Yao M, Tanaka I |
(2011) "Molecular
basis of dihydrouridine formation on tRNA."
Proc.Natl.Acad.Sci.USA, 108,
19593-19598. doi: 10.1073/pnas.1112352108.
|
Trna-dihydrouridine synthase from thermus thermophilus
in complex with trna . SNAP output
|
|
3bo0
|
ribosome |
cryo-EM (9.6 Å) |
Menetret JF, Schaletzky J, Clemons WM, Osborne AR,
Skanland SS, Denison C, Gygi SP, Kirkpatrick DS, Park E,
Ludtke SJ, Rapoport TA, Akey CW |
(2007) "Ribosome
binding of a single copy of the SecY complex:
implications for protein translocation."
Mol.Cell, 28, 1083-1092. doi:
10.1016/j.molcel.2007.10.034.
|
Ribosome-secy complex . SNAP output
|
|
3bo1
|
ribosome |
cryo-EM (9.6 Å) |
Menetret JF, Schaletzky J, Clemons WM, Osborne AR,
Skanland SS, Denison C, Gygi SP, Kirkpatrick DS, Park E,
Ludtke SJ, Rapoport TA, Akey CW |
(2007) "Ribosome
binding of a single copy of the SecY complex:
implications for protein translocation."
Mol.Cell, 28, 1083-1092. doi:
10.1016/j.molcel.2007.10.034.
|
Ribosome-secy complex . SNAP output
|
|
3bo2
|
nuclear protein-RNA |
X-ray (3.31 Å) |
Lipchock SV, Strobel SA |
(2008) "A
relaxed active site after exon ligation by the group I
intron." Proc.Natl.Acad.Sci.Usa,
105, 5699-5704. doi: 10.1073/pnas.0712016105.
|
A relaxed active site following exon ligation by a
group i intron . SNAP
output
|
|
3bo3
|
nuclear protein-RNA |
X-ray (3.4 Å) |
Lipchock SV, Strobel SA |
(2008) "A
relaxed active site after exon ligation by the group I
intron." Proc.Natl.Acad.Sci.Usa,
105, 5699-5704. doi: 10.1073/pnas.0712016105.
|
A relaxed active site following exon ligation by a
group i intron . SNAP
output
|
|
3bo4
|
nuclear protein-RNA |
X-ray (3.33 Å) |
Lipchock SV, Strobel SA |
(2008) "A
relaxed active site after exon ligation by the group I
intron." Proc.Natl.Acad.Sci.Usa,
105, 5699-5704. doi: 10.1073/pnas.0712016105.
|
A relaxed active site following exon ligation by a
group i intron . SNAP
output
|
|
3boy
|
transcription-RNA |
X-ray (1.7 Å) |
Kumarevel T, Balasundaresan D, Jeyakanthan J, Shinkai
A, Yokoyama S, Kumar PKR |
"Crystal Structure of HutP complexed with the 55-mer
RNA." |
Crystal structure of the hutp antitermination complex
bound to the hut mrna . SNAP output
|
|
3bsb
|
RNA binding protein-RNA |
X-ray (2.8 Å) |
Gupta YK, Nair DT, Wharton RP, Aggarwal AK |
(2008) "Structures
of human Pumilio with noncognate RNAs reveal molecular
mechanisms for binding promiscuity."
Structure, 16, 549-557. doi:
10.1016/j.str.2008.01.006.
|
Crystal structure of human pumilio1 in complex with
cyclinb reverse RNA . SNAP output
|
|
3bsn
|
transferase-RNA |
X-ray (1.8 Å) |
Zamyatkin DF, Parra F, Alonso JM, Harki DA, Peterson
BR, Grochulski P, Ng KK |
(2008) "Structural
insights into mechanisms of catalysis and inhibition in
norwalk virus polymerase." J.Biol.Chem.,
283, 7705-7712. doi: 10.1074/jbc.M709563200.
|
Norwalk virus polymerase bound to 5-nitrocytidine
triphosphate and primer-template RNA . SNAP output
|
|
3bso
|
transferase-RNA |
X-ray (1.74 Å) |
Zamyatkin DF, Parra F, Alonso JM, Harki DA, Peterson
BR, Grochulski P, Ng KK |
(2008) "Structural
insights into mechanisms of catalysis and inhibition in
norwalk virus polymerase." J.Biol.Chem.,
283, 7705-7712. doi: 10.1074/jbc.M709563200.
|
Norwalk virus polymerase bound to cytidine
5'-triphosphate and primer-template RNA . SNAP output
|
|
3bsx
|
RNA binding protein-RNA |
X-ray (2.32 Å) |
Gupta YK, Nair DT, Wharton RP, Aggarwal AK |
(2008) "Structures
of human Pumilio with noncognate RNAs reveal molecular
mechanisms for binding promiscuity."
Structure, 16, 549-557. doi:
10.1016/j.str.2008.01.006.
|
Crystal structure of human pumilio 1 in complex with
puf5 RNA . SNAP
output
|
|
3bt7
|
transferase-RNA |
X-ray (2.43 Å) |
Alian A, Lee TT, Griner SL, Stroud RM, Finer-Moore
J |
(2008) "Structure
of a TrmA-RNA complex: A consensus RNA fold contributes
to substrate selectivity and catalysis in m5U
methyltransferases."
Proc.Natl.Acad.Sci.Usa, 105,
6876-6881. doi: 10.1073/pnas.0802247105.
|
Structure of e. coli 5-methyluridine methyltransferase
trma in complex with 19 nucleotide t-arm analogue .
SNAP output
|
|
3bx2
|
transcription, RNA binding protein-RNA |
X-ray (2.84 Å) |
Miller MT, Higgin JJ, Hall TMT |
(2008) "Basis of
altered RNA-binding specificity by PUF proteins
revealed by crystal structures of yeast Puf4p."
Nat.Struct.Mol.Biol., 15,
397-402. doi: 10.1038/nsmb.1390.
|
Puf4 RNA binding domain bound to ho endonuclease RNA 3'
utr recognition sequence . SNAP output
|
|
3bx3
|
transcription, RNA binding protein-RNA |
X-ray (3.0 Å) |
Miller MT, Higgin JJ, Hall TMT |
(2008) "Basis of
altered RNA-binding specificity by PUF proteins
revealed by crystal structures of yeast Puf4p."
Nat.Struct.Mol.Biol., 15,
397-402. doi: 10.1038/nsmb.1390.
|
Puf4 t650c-c724r mutant bound to cox17 RNA 3' utr
recognition sequence . SNAP output
|
|
3cc2
|
ribosome |
X-ray (2.4 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
The refined crystal structure of the haloarcula
marismortui large ribosomal subunit at 2.4 angstrom
resolution with rrna sequence for the 23s rrna and
genome-derived sequences for r-proteins . SNAP output
|
|
3cc4
|
ribosome |
X-ray (2.7 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Co-crystal structure of anisomycin bound to the 50s
ribosomal subunit . SNAP
output
|
|
3cc7
|
ribosome |
X-ray (2.7 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation c2487u . SNAP output
|
|
3cce
|
ribosome |
X-ray (2.75 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation u2535a . SNAP output
|
|
3ccj
|
ribosome |
X-ray (3.3 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation c2534u . SNAP output
|
|
3ccl
|
ribosome |
X-ray (2.9 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation u2535c. density for
anisomycin is visible but not included in model. .
SNAP output
|
|
3ccm
|
ribosome |
X-ray (2.55 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation g2611u . SNAP output
|
|
3ccq
|
ribosome |
X-ray (2.9 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation a2488u . SNAP output
|
|
3ccr
|
ribosome |
X-ray (3.0 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation a2488c. density for
anisomycin is visible but not included in the model. .
SNAP output
|
|
3ccs
|
ribosome |
X-ray (2.95 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation g2482a . SNAP output
|
|
3ccu
|
ribosome |
X-ray (2.8 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation g2482c . SNAP output
|
|
3ccv
|
ribosome |
X-ray (2.9 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Structure of anisomycin resistant 50s ribosomal
subunit: 23s rrna mutation g2616a . SNAP output
|
|
3cd6
|
ribosome |
X-ray (2.75 Å) |
Blaha G, Gurel G, Schroeder SJ, Moore PB, Steitz
TA |
(2008) "Mutations
outside the anisomycin-binding site can make ribosomes
drug-resistant." J.Mol.Biol.,
379, 505-519. doi: 10.1016/j.jmb.2008.03.075.
|
Co-cystal of large ribosomal subunit mutant g2616a with
cc-puromycin . SNAP
output
|
|
3cf5
|
ribosome-antibiotic |
X-ray (3.3 Å) |
Harms JM, Wilson DN, Schluenzen F, Connell SR,
Stachelhaus T, Zaborowska Z, Spahn CM, Fucini P |
(2008) "Translational
Regulation Via L11: Molecular Switches on the Ribosome
Turned on and Off by Thiostrepton and Micrococcin."
Mol.Cell, 30, 26. doi:
10.1016/J.MOLCEL.2008.01.009.
|
Thiopeptide antibiotic thiostrepton bound to the large
ribosomal subunit of deinococcus radiodurans . SNAP output
|
|
3ciy
|
immune system-RNA |
X-ray (3.41 Å) |
Liu L, Botos I, Wang Y, Leonard JN, Shiloach J, Segal
DM, Davies DR |
(2008) "Structural
basis of toll-like receptor 3 signaling with
double-stranded RNA." Science,
320, 379-381. doi: 10.1126/science.1155406.
|
Mouse toll-like receptor 3 ectodomain complexed with
double-stranded RNA . SNAP output
|
|
3cma
|
ribosome |
X-ray (2.8 Å) |
Simonovic M, Steitz TA |
(2008) "Peptidyl-CCA
deacylation on the ribosome promoted by induced fit and
the O3'-hydroxyl group of A76 of the unacylated A-site
tRNA." Rna, 14,
2372-2378. doi: 10.1261/rna.1118908.
|
The structure of cca and cca-phe-cap-bio bound to the
large ribosomal subunit of haloarcula marismortui .
SNAP output
|
|
3cme
|
ribosome |
X-ray (2.95 Å) |
Simonovic M, Steitz TA |
(2008) "Peptidyl-CCA
deacylation on the ribosome promoted by induced fit and
the O3'-hydroxyl group of A76 of the unacylated A-site
tRNA." Rna, 14,
2372-2378. doi: 10.1261/rna.1118908.
|
The structure of ca and cca-phe-cap-bio bound to the
large ribosomal subunit of haloarcula marismortui .
SNAP output
|
|
3cpw
|
ribosome |
X-ray (2.7 Å) |
Ippolito JA, Kanyo ZK, Wang D, Franceschi FJ, Moore
PB, Steitz TA, Duffy EM |
(2008) "Crystal
Structure of the Oxazolidinone Antibiotic Linezolid
Bound to the 50S Ribosomal Subunit."
J.Med.Chem., 51, 3353-3356.
doi: 10.1021/jm800379d.
|
The structure of the antibiotic linezolid bound to the
large ribosomal subunit of haloarcula marismortui .
SNAP output
|
|
3cul
|
RNA-RNA binding |
X-ray (2.8 Å) |
Xiao H, Murakami H, Suga H, Ferre-D'Amare AR |
(2008) "Structural
basis of specific tRNA aminoacylation by a small in
vitro selected ribozyme." Nature,
454, 358-361. doi: 10.1038/nature07033.
|
Aminoacyl-trna synthetase ribozyme . SNAP output
|
|
3cun
|
RNA-RNA binding |
X-ray (3.0 Å) |
Xiao H, Murakami H, Suga H, Ferre-D'Amare AR |
(2008) "Structural
basis of specific tRNA aminoacylation by a small in
vitro selected ribozyme." Nature,
454, 358-361. doi: 10.1038/nature07033.
|
Aminoacyl-trna synthetase ribozyme . SNAP output
|
|
3cxc
|
ribosome |
X-ray (3.0 Å) |
Zhou J, Bhattacharjee A, Chen S, Chen Y, Duffy E,
Farmer J, Goldberg J, Hanselmann R, Ippolito JA, Lou R,
Orbin A, Oyelere A, Salvino J, Springer D, Tran J, Wang
D, Wu Y, Johnson G |
(2008) "Design
at the atomic level: design of biaryloxazolidinones as
potent orally active antibiotics."
Bioorg.Med.Chem.Lett., 18,
6175-6178. doi: 10.1016/j.bmcl.2008.10.011.
|
The structure of an enhanced oxazolidinone inhibitor
bound to the 50s ribosomal subunit of h. marismortui .
SNAP output
|
|
3cz3
|
viral protein-RNA |
X-ray (3.23 Å) |
Ma JB, Li F, Ding SW, Patel DJ |
"Structural Basis for siRNA Recognition by 2b, a
Viral Suppressor of Non-Cell Autonomous RNA
Silencing." |
Crystal structure of tomato aspermy virus 2b in complex
with sirna . SNAP
output
|
|
3dd2
|
hydrolase-hydrolase inhibitor-RNA |
X-ray (1.9 Å) |
Long SB, Long MB, White RR, Sullenger BA |
(2008) "Crystal
structure of an RNA aptamer bound to thrombin."
Rna, 14, 2504-2512. doi:
10.1261/rna.1239308.
|
Crystal structure of an RNA aptamer bound to human
thrombin . SNAP
output
|
|
3deg
|
ribosome |
cryo-EM (10.9 Å) |
Connell SR, Topf M, Qin Y, Wilson DN, Mielke T,
Fucini P, Nierhaus KH, Spahn CMT |
(2008) "A new
tRNA intermediate revealed on the ribosome during
EF4-mediated back-translocation."
Nat.Struct.Mol.Biol., 15,
910-915. doi: 10.1038/nsmb.1469.
|
Complex of elongating escherichia coli 70s ribosome and
ef4(lepa)-gmppnp . SNAP
output
|
|
3dh3
|
isomerase-RNA |
X-ray (3.0 Å) |
Alian A, DeGiovanni A, Griner SL, Finer-Moore JS,
Stroud RM |
(2009) "Crystal
structure of an RluF-RNA complex: a base-pair
rearrangement is the key to selectivity of RluF for
U2604 of the ribosome." J.Mol.Biol.,
388, 785-800. doi: 10.1016/j.jmb.2009.03.029.
|
Crystal structure of rluf in complex with a 22
nucleotide RNA substrate . SNAP output
|
|
3dkn
|
protein transport-RNA |
cryo-EM (8.7 Å) |
Menetret JF, Hegde RS, Aguiar M, Gygi SP, Park E,
Rapoport TA, Akey CW |
(2008) "Single
copies of Sec61 and TRAP associate with a
nontranslating mammalian ribosome."
Structure, 16, 1126-1137.
doi: 10.1016/j.str.2008.05.003.
|
Sec61 in the canine ribosome-channel complex from the
endoplasmic reticulum . SNAP output
|
|
3dll
|
ribosome |
X-ray (3.5 Å) |
Wilson DN, Schluenzen F, Harms JM, Starosta AL,
Connell SR, Fucini P |
(2008) "The
oxazolidinone antibiotics perturb the ribosomal
peptidyl-transferase center and effect tRNA
positioning." Proc.Natl.Acad.Sci.Usa,
105, 13339-13344. doi: 10.1073/pnas.0804276105.
|
The oxazolidinone antibiotics perturb the ribosomal
peptidyl-transferase center and effect trna positioning
. SNAP output
|
|
3egz
|
RNA |
X-ray (2.2 Å) |
Xiao H, Edwards TE, Ferre-D'Amare AR |
(2008) "Structural
basis for specific, high-affinity tetracycline binding
by an in vitro evolved aptamer and artificial
riboswitch." Chem.Biol.,
15, 1125-1137. doi: 10.1016/j.chembiol.2008.09.004.
|
Crystal structure of an in vitro evolved tetracycline
aptamer and artificial riboswitch . SNAP output
|
|
3eph
|
transferase-RNA |
X-ray (2.95 Å) |
Zhou C, Huang RH |
(2008) "Crystallographic
snapshots of eukaryotic dimethylallyltransferase acting
on tRNA: insight into tRNA recognition and reaction
mechanism." Proc.Natl.Acad.Sci.Usa,
105, 16142-16147. doi: 10.1073/pnas.0805680105.
|
Crystallographic snapshots of eukaryotic
dimethylallyltransferase acting on trna: insight into
trna recognition and reaction mechanism . SNAP output
|
|
3epj
|
transferase-RNA |
X-ray (3.1 Å) |
Zhou C, Huang RH |
(2008) "Crystallographic
snapshots of eukaryotic dimethylallyltransferase acting
on tRNA: insight into tRNA recognition and reaction
mechanism." Proc.Natl.Acad.Sci.Usa,
105, 16142-16147. doi: 10.1073/pnas.0805680105.
|
Crystallographic snapshots of eukaryotic
dimethylallyltransferase acting on trna: insight into
trna recognition and reaction mechanism . SNAP output
|
|
3epk
|
transferase-RNA |
X-ray (3.2 Å) |
Zhou C, Huang RH |
(2008) "Crystallographic
snapshots of eukaryotic dimethylallyltransferase acting
on tRNA: insight into tRNA recognition and reaction
mechanism." Proc.Natl.Acad.Sci.Usa,
105, 16142-16147. doi: 10.1073/pnas.0805680105.
|
Crystallographic snapshots of eukaryotic
dimethylallyltransferase acting on trna: insight into
trna recognition and reaction mechanism . SNAP output
|
|
3epl
|
transferase-RNA |
X-ray (3.6 Å) |
Zhou C, Huang RH |
(2008) "Crystallographic
snapshots of eukaryotic dimethylallyltransferase acting
on tRNA: insight into tRNA recognition and reaction
mechanism." Proc.Natl.Acad.Sci.Usa,
105, 16142-16147. doi: 10.1073/pnas.0805680105.
|
Crystallographic snapshots of eukaryotic
dimethylallyltransferase acting on trna: insight into
trna recognition and reaction mechanism . SNAP output
|
|
3eqt
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Li X, Ranjith-Kumar CT, Brooks MT, Dharmaiah S, Herr
AB, Kao C, Li P |
(2009) "The
RIG-I-like Receptor LGP2 Recognizes the Termini of
Double-stranded RNA." J.Biol.Chem.,
284, 13881-13891. doi: 10.1074/jbc.M900818200.
|
Crystal structure of human lgp2 c-terminal domain in
complex with dsrna . SNAP output
|
|
3er9
|
transcription, transferase-RNA |
X-ray (2.06 Å) |
Li C, Li H, Zhou S, Sun E, Yoshizawa J, Poulos TL,
Gershon PD |
(2009) "Polymerase
Translocation with Respect to Single-Stranded Nucleic
Acid: Looping or Wrapping of Primer around a Poly(A)
Polymerase." Structure,
17, 680-689. doi: 10.1016/j.str.2009.03.012.
|
Crystal structure of the heterodimeric vaccinia virus
mrna polyadenylate polymerase complex with uu and
3'-deoxy atp . SNAP
output
|
|
3ex7
|
hydrolase-RNA binding protein-RNA |
X-ray (2.301 Å) |
Nielsen KH, Chamieh H, Andersen CB, Fredslund F,
Hamborg K, Le Hir H, Andersen GR |
(2009) "Mechanism
of ATP turnover inhibition in the EJC."
Rna, 15, 67-75. doi: 10.1261/rna.1283109.
|
The crystal structure of ejc in its transition state .
SNAP output
|
|
3fht
|
hydrolase-RNA |
X-ray (2.2 Å) |
von Moeller H, Basquin C, Conti E |
(2009) "The mRNA
export protein DBP5 binds RNA and the cytoplasmic
nucleoporin NUP214 in a mutually exclusive manner."
Nat.Struct.Mol.Biol., 16,
247-254. doi: 10.1038/nsmb.1561.
|
Crystal structure of human dbp5 in complex with amppnp
and RNA . SNAP
output
|
|
3foz
|
transferase-RNA |
X-ray (2.5 Å) |
Seif E, Hallberg BM |
(2009) "RNA-Protein
Mutually Induced Fit: STRUCTURE OF ESCHERICHIA COLI
ISOPENTENYL-tRNA TRANSFERASE IN COMPLEX WITH
tRNA(Phe)." J.Biol.Chem.,
284, 6600-6604. doi: 10.1074/jbc.C800235200.
|
Structure of e. coli isopentenyl-trna transferase in
complex with e. coli trna(phe) . SNAP output
|
|
3fte
|
transferase-RNA |
X-ray (3.0 Å) |
Tu C, Tropea JE, Austin BP, Court DL, Waugh DS, Ji
X |
(2009) "Structural
Basis for Binding of RNA and Cofactor by a KsgA
Methyltransferase." Structure,
17, 374-385. doi: 10.1016/j.str.2009.01.010.
|
Crystal structure of a. aeolicus ksga in complex with
RNA . SNAP output
|
|
3ftf
|
transferase-RNA |
X-ray (2.8 Å) |
Tu C, Tropea JE, Austin BP, Court DL, Waugh DS, Ji
X |
(2009) "Structural
Basis for Binding of RNA and Cofactor by a KsgA
Methyltransferase." Structure,
17, 374-385. doi: 10.1016/j.str.2009.01.010.
|
Crystal structure of a. aeolicus ksga in complex with
RNA and sah . SNAP
output
|
|
3g0h
|
hydrolase-RNA |
X-ray (2.7 Å) |
Collins R, Karlberg T, Lehtio L, Schutz P, van den
Berg S, Dahlgren LG, Hammarstrom M, Weigelt J, Schuler
H |
(2009) "The
DEXD/H-box RNA Helicase DDX19 Is Regulated by an
{alpha}-Helical Switch." J.Biol.Chem.,
284, 10296-10300. doi: 10.1074/jbc.C900018200.
|
Human dead-box RNA helicase ddx19, in complex with an
atp-analogue and RNA . SNAP output
|
|
3g4s
|
ribosome |
X-ray (3.2 Å) |
Gurel G, Blaha G, Moore PB, Steitz TA |
(2009) "U2504
determines the species specificity of the A-site cleft
antibiotics: the structures of tiamulin,
homoharringtonine, and bruceantin bound to the
ribosome." J.Mol.Biol.,
389, 146-156. doi: 10.1016/j.jmb.2009.04.005.
|
Co-crystal structure of tiamulin bound to the large
ribosomal subunit . SNAP
output
|
|
3g6e
|
ribosome |
X-ray (2.7 Å) |
Gurel G, Blaha G, Moore PB, Steitz TA |
(2009) "U2504
determines the species specificity of the A-site cleft
antibiotics: the structures of tiamulin,
homoharringtonine, and bruceantin bound to the
ribosome." J.Mol.Biol.,
389, 146-156. doi: 10.1016/j.jmb.2009.04.005.
|
Co-crystal structure of homoharringtonine bound to the
large ribosomal subunit . SNAP output
|
|
3g71
|
ribosome |
X-ray (2.85 Å) |
Gurel G, Blaha G, Moore PB, Steitz TA |
(2009) "U2504
determines the species specificity of the A-site cleft
antibiotics: the structures of tiamulin,
homoharringtonine, and bruceantin bound to the
ribosome." J.Mol.Biol.,
389, 146-156. doi: 10.1016/j.jmb.2009.04.005.
|
Co-crystal structure of bruceantin bound to the large
ribosomal subunit . SNAP
output
|
|
3g8s
|
RNA binding protein-RNA |
X-ray (3.1 Å) |
Cochrane JC, Lipchock SV, Smith KD, Strobel SA |
(2009) "Structural
and chemical basis for glucosamine 6-phosphate binding
and activation of the glmS ribozyme."
Biochemistry, 48, 3239-3246.
doi: 10.1021/bi802069p.
|
Crystal structure of the pre-cleaved bacillus anthracis
glms ribozyme . SNAP
output
|
|
3g8t
|
RNA binding protein-RNA |
X-ray (3.0 Å) |
Cochrane JC, Lipchock SV, Smith KD, Strobel SA |
(2009) "Structural
and chemical basis for glucosamine 6-phosphate binding
and activation of the glmS ribozyme."
Biochemistry, 48, 3239-3246.
doi: 10.1021/bi802069p.
|
Crystal structure of the g33a mutant bacillus anthracis
glms ribozyme bound to glcn6p . SNAP output
|
|
3g96
|
RNA binding protein-RNA |
X-ray (3.01 Å) |
Cochrane JC, Lipchock SV, Smith KD, Strobel SA |
(2009) "Structural
and chemical basis for glucosamine 6-phosphate binding
and activation of the glmS ribozyme."
Biochemistry, 48, 3239-3246.
doi: 10.1021/bi802069p.
|
Crystal structure of the bacillus anthracis glms
ribozyme bound to man6p . SNAP output
|
|
3g9c
|
RNA binding protein-RNA |
X-ray (2.9 Å) |
Cochrane JC, Lipchock SV, Smith KD, Strobel SA |
(2009) "Structural
and chemical basis for glucosamine 6-phosphate binding
and activation of the glmS ribozyme."
Biochemistry, 48, 3239-3246.
doi: 10.1021/bi802069p.
|
Crystal structure of the product bacillus anthracis
glms ribozyme . SNAP
output
|
|
3g9y
|
transcription-RNA |
X-ray (1.4 Å) |
Loughlin FE, Mansfield RE, Vaz PM, McGrath AP,
Setiyaputra S, Gamsjaeger R, Chen ES, Morris BJ, Guss JM,
Mackay JP |
(2009) "The zinc
fingers of the SR-like protein ZRANB2 are
single-stranded RNA-binding domains that recognize 5'
splice site-like sequences."
Proc.Natl.Acad.Sci.USA, 106,
5581-5586. doi: 10.1073/pnas.0802466106.
|
Crystal structure of the second zinc finger from
zranb2-znf265 bound to 6 nt ssrna sequence agguaa .
SNAP output
|
|
3gib
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Link TM, Valentin-Hansen P, Brennan RG |
(2009) "Structure
of Escherichia coli Hfq bound to polyriboadenylate
RNA." Proc.Natl.Acad.Sci.USA,
106, 19292-19297. doi: 10.1073/pnas.0908744106.
|
Crystal structure of the complex of the e. coli hfq
with poly(a) . SNAP
output
|
|
3gpq
|
viral protein-RNA |
X-ray (2.0 Å) |
Malet H, Coutard B, Jamal S, Dutartre H, Papageorgiou
N, Neuvonen M, Ahola T, Forrester N, Gould EA, Lafitte D,
Ferron F, Lescar J, Gorbalenya AE, de Lamballerie X,
Canard B |
(2009) "The
crystal structures of Chikungunya and Venezuelan equine
encephalitis virus nsP3 macro domains define a
conserved adenosine binding pocket."
J.Virol., 83, 6534-6545. doi:
10.1128/JVI.00189-09.
|
Crystal structure of macro domain of chikungunya virus
in complex with RNA . SNAP output
|
|
3h5x
|
transferase-RNA |
X-ray (1.77 Å) |
Zamyatkin DF, Parra F, Machin A, Grochulski P, Ng
KK |
(2009) "Binding
of 2'-amino-2'-deoxycytidine-5'-triphosphate to
norovirus polymerase induces rearrangement of the
active site." J.Mol.Biol.,
390, 10-16. doi: 10.1016/j.jmb.2009.04.069.
|
Crystal structure of
2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to
norovirus gii RNA polymerase . SNAP output
|
|
3h5y
|
transferase-RNA |
X-ray (1.77 Å) |
Zamyatkin DF, Parra F, Machin A, Grochulski P, Ng
KK |
(2009) "Binding
of 2'-amino-2'-deoxycytidine-5'-triphosphate to
norovirus polymerase induces rearrangement of the
active site." J.Mol.Biol.,
390, 10-16. doi: 10.1016/j.jmb.2009.04.069.
|
Norovirus polymerase+primer-template+ctp complex at 6
mm mncl2 . SNAP
output
|
|
3hay
|
isomerase-biosynthetic protein-RNA |
X-ray (4.99 Å) |
Duan J, Li L, Lu J, Wang W, Ye K |
(2009) "Structural
mechanism of substrate RNA recruitment in H/ACA
RNA-guided pseudouridine synthase."
Mol.Cell, 34, 427-439. doi:
10.1016/j.molcel.2009.05.005.
|
Crystal structure of a substrate-bound full h-aca rnp
from pyrococcus furiosus . SNAP output
|
|
3hhn
|
ligase-RNA |
X-ray (2.987 Å) |
Shechner DM, Grant RA, Bagby SC, Koldobskaya Y,
Piccirilli JA, Bartel DP |
(2009) "Crystal
structure of the catalytic core of an RNA-polymerase
ribozyme." Science, 326,
1271-1275. doi: 10.1126/science.1174676.
|
Crystal structure of class i ligase ribozyme
self-ligation product, in complex with u1a rbd .
SNAP output
|
|
3hhz
|
viral protein-RNA |
X-ray (3.5 Å) |
Green TJ, Luo M |
(2009) "Structure
of the vesicular stomatitis virus nucleocapsid in
complex with the nucleocapsid-binding domain of the
small polymerase cofactor, P."
Proc.Natl.Acad.Sci.USA, 106,
11713-11718. doi: 10.1073/pnas.0903228106.
|
Complex of the vesicular stomatitis virus nucleocapsid
and the nucleocapsid-binding domain of the
phosphoprotein . SNAP
output
|
|
3hjw
|
isomerase-RNA |
X-ray (2.35 Å) |
Liang B, Zhou J, Kahen E, Terns RM, Terns MP, Li
H |
(2009) "Structure
of a functional ribonucleoprotein pseudouridine
synthase bound to a substrate RNA."
Nat.Struct.Mol.Biol., 16,
740-746. doi: 10.1038/nsmb.1624.
|
Structure of a functional ribonucleoprotein
pseudouridine synthase bound to a substrate RNA .
SNAP output
|
|
3hjy
|
isomerase-RNA |
X-ray (3.65 Å) |
Liang B, Zhou J, Kahen E, Terns RM, Terns MP, Li
H |
(2009) "Structure
of a functional ribonucleoprotein pseudouridine
synthase bound to a substrate RNA."
Nat.Struct.Mol.Biol., 16,
740-746. doi: 10.1038/nsmb.1624.
|
Structure of a functional ribonucleoprotein
pseudouridine synthase bound to a substrate RNA .
SNAP output
|
|
3hl2
|
transferase |
X-ray (2.81 Å) |
Palioura S, Sherrer RL, Steitz TA, Soll D, Simonovic
M |
(2009) "The
human SepSecS-tRNASec complex reveals the mechanism of
selenocysteine formation." Science,
325, 321-325. doi: 10.1126/science.1173755.
|
The crystal structure of the human sepsecs-trnasec
complex . SNAP
output
|
|
3hsb
|
RNA binding protein-RNA |
X-ray (2.2 Å) |
Someya T, Baba S, Fujimoto M, Kawai G, Kumasaka T,
Nakamura K |
(2012) "Crystal
structure of Hfq from Bacillus subtilis in complex with
SELEX-derived RNA aptamer: insight into RNA-binding
properties of bacterial Hfq." Nucleic Acids
Res., 40, 1856-1867. doi:
10.1093/nar/gkr892.
|
Crystal structure of ymah (hfq) from bacillus subtilis
in complex with an RNA aptamer . SNAP output
|
|
3htx
|
transferase-RNA |
X-ray (3.1 Å) |
Huang Y, Ji L, Huang Q, Vassylyev DG, Chen X, Ma
JB |
(2009) "Structural
insights into mechanisms of the small RNA
methyltransferase HEN1." Nature,
461, 823-827. doi: 10.1038/nature08433.
|
Crystal structure of small RNA methyltransferase hen1 .
SNAP output
|
|
3i55
|
ribosome-antibiotic |
X-ray (3.11 Å) |
Gurel G, Blaha G, Steitz TA, Moore PB |
(2009) "Structures
of triacetyloleandomycin and mycalamide A bind to the
large ribosomal subunit of Haloarcula marismortui."
Antimicrob.Agents Chemother.,
53, 5010-5014. doi: 10.1128/AAC.00817-09.
|
Co-crystal structure of mycalamide a bound to the large
ribosomal subunit . SNAP
output
|
|
3i56
|
ribosome-antibiotic |
X-ray (2.9 Å) |
Gurel G, Blaha G, Steitz TA, Moore PB |
(2009) "Structures
of triacetyloleandomycin and mycalamide A bind to the
large ribosomal subunit of Haloarcula marismortui."
Antimicrob.Agents Chemother.,
53, 5010-5014. doi: 10.1128/AAC.00817-09.
|
Co-crystal structure of triacetyloleandomcyin bound to
the large ribosomal subunit . SNAP output
|
|
3i5x
|
hydrolase-RNA |
X-ray (1.9 Å) |
Del Campo M, Lambowitz AM |
(2009) "Structure
of the Yeast DEAD box protein Mss116p reveals two
wedges that crimp RNA." Mol.Cell,
35, 598-609. doi: 10.1016/j.molcel.2009.07.032.
|
Structure of mss116p bound to ssrna and amp-pnp .
SNAP output
|
|
3i5y
|
hydrolase-RNA |
X-ray (2.49 Å) |
Del Campo M, Lambowitz AM |
(2009) "Structure
of the Yeast DEAD box protein Mss116p reveals two
wedges that crimp RNA." Mol.Cell,
35, 598-609. doi: 10.1016/j.molcel.2009.07.032.
|
Structure of mss116p bound to ssrna containing a single
5-bru and amp-pnp . SNAP
output
|
|
3i61
|
hydrolase-RNA |
X-ray (2.1 Å) |
Del Campo M, Lambowitz AM |
(2009) "Structure
of the Yeast DEAD box protein Mss116p reveals two
wedges that crimp RNA." Mol.Cell,
35, 598-609. doi: 10.1016/j.molcel.2009.07.032.
|
Structure of mss116p bound to ssrna and adp-beryllium
fluoride . SNAP
output
|
|
3i62
|
hydrolase-RNA |
X-ray (1.95 Å) |
Del Campo M, Lambowitz AM |
(2009) "Structure
of the Yeast DEAD box protein Mss116p reveals two
wedges that crimp RNA." Mol.Cell,
35, 598-609. doi: 10.1016/j.molcel.2009.07.032.
|
Structure of mss116p bound to ssrna and adp-aluminum
fluoride . SNAP
output
|
|
3iab
|
hydrolase-RNA |
X-ray (2.7 Å) |
Perederina A, Esakova O, Quan C, Khanova E,
Krasilnikov AS |
(2010) "Eukaryotic
ribonucleases P/MRP: the crystal structure of the P3
domain." Embo J., 29,
761-769. doi: 10.1038/emboj.2009.396.
|
Crystal structure of rnase p -rnase mrp proteins pop6,
pop7 in a complex with the p3 domain of rnase mrp RNA .
SNAP output
|
|
3ice
|
transcription regulator-RNA |
X-ray (2.8 Å) |
Thomsen ND, Berger JM |
(2009) "Running
in reverse: the structural basis for translocation
polarity in hexameric helicases."
Cell(Cambridge,Mass.), 139,
523-534. doi: 10.1016/j.cell.2009.08.043.
|
Rho transcription termination factor bound to RNA and
adp-bef3 . SNAP
output
|
|
3icq
|
RNA binding protein |
X-ray (3.2 Å) |
Cook AG, Fukuhara N, Jinek M, Conti E |
(2009) "Structures
of the tRNA export factor in the nuclear and cytosolic
states." Nature, 461,
60-65. doi: 10.1038/nature08394.
|
Karyopherin nuclear state . SNAP output
|
|
3id5
|
transferase-ribosomal protein-RNA |
X-ray (4.01 Å) |
Ye K, Jia R, Lin J, Ju M, Peng J, Xu A, Zhang L |
(2009) "Structural
organization of box C/D RNA-guided RNA
methyltransferase."
Proc.Natl.Acad.Sci.USA, 106,
13808-13813. doi: 10.1073/pnas.0905128106.
|
Crystal structure of sulfolobus solfataricus c-d rnp
assembled with nop5, fibrillarin, l7ae and a split half
c-d RNA . SNAP
output
|
|
3ie1
|
hydrolase-RNA |
X-ray (2.85 Å) |
Ishikawa H, Nakagawa N, Kuramitsu S, Masui R |
"Crystal structure of H380A mutant TTHA0252 from
Thermus thermophilus HB8 complexed with RNA." |
Crystal structure of h380a mutant ttha0252 from thermus
thermophilus hb8 complexed with RNA . SNAP output
|
|
3iem
|
hydrolase-RNA |
X-ray (2.5 Å) |
Ishikawa H, Nakagawa N, Kuramitsu S, Masui R |
"Crystal Structure of TTHA0252 from Thermus
thermophilus HB8 complexed with RNA analog." |
Crystal structure of ttha0252 from thermus thermophilus
hb8 complexed with RNA analog . SNAP output
|
|
3iev
|
nucleotide binding protein-RNA |
X-ray (1.9 Å) |
Tu C, Zhou X, Tropea JE, Austin BP, Waugh DS, Court
DL, Ji X |
(2009) "Structure
of ERA in complex with the 3' end of 16S rRNA:
implications for ribosome biogenesis."
Proc.Natl.Acad.Sci.USA, 106,
14843-14848. doi: 10.1073/pnas.0904032106.
|
Crystal structure of era in complex with mggnp and the
3' end of 16s rrna . SNAP output
|
|
3irw
|
RNA binding protein-RNA |
X-ray (2.7 Å) |
Smith KD, Lipchock SV, Ames TD, Wang J, Breaker RR,
Strobel SA |
(2009) "Structural
basis of ligand binding by a c-di-GMP riboswitch."
Nat.Struct.Mol.Biol., 16,
1218-1223. doi: 10.1038/nsmb.1702.
|
Structure of a c-di-gmp riboswitch from v. cholerae .
SNAP output
|
|
3ivk
|
immune system - RNA |
X-ray (3.1 Å) |
Shechner DM, Grant RA, Bagby SC, Koldobskaya Y,
Piccirilli JA, Bartel DP |
(2009) "Crystal
structure of the catalytic core of an RNA-polymerase
ribozyme." Science, 326,
1271-1275. doi: 10.1126/science.1174676.
|
Crystal structure of the catalytic core of an RNA
polymerase ribozyme complexed with an antigen binding
antibody fragment . SNAP
output
|
|
3iwn
|
RNA-RNA binding protein |
X-ray (3.2 Å) |
Kulshina N, Baird NJ, Ferre-D'Amare AR |
(2009) "Recognition
of the bacterial second messenger cyclic diguanylate by
its cognate riboswitch."
Nat.Struct.Mol.Biol., 16,
1212-1217. doi: 10.1038/nsmb.1701.
|
Co-crystal structure of a bacterial c-di-gmp riboswitch
. SNAP output
|
|
3iyq
|
ribosomal protein-RNA |
cryo-EM (13.0 Å) |
Weis F, Bron P, Giudice E, Rolland JP, Thomas D,
Felden B, Gillet R |
(2010) "tmRNA-SmpB:
a journey to the centre of the bacterial ribosome."
Embo J., 29, 3810-3818. doi:
10.1038/emboj.2010.252.
|
Tmrna-smpb: a journey to the center of the bacterial
ribosome . SNAP
output
|
|
3iyr
|
ribosomal protein-RNA |
cryo-EM (13.0 Å) |
Weis F, Bron P, Giudice E, Rolland JP, Thomas D,
Felden B, Gillet R |
(2010) "tmRNA-SmpB:
a journey to the centre of the bacterial ribosome."
Embo J., 29, 3810-3818. doi:
10.1038/emboj.2010.252.
|
Tmrna-smpb: a journey to the center of the bacterial
ribosome . SNAP
output
|
|
3iz4
|
RNA binding protein-RNA |
cryo-EM (13.6 Å) |
Fu J, Hashem Y, Wower I, Lei J, Liao HY, Zwieb C,
Wower J, Frank J |
(2010) "Visualizing
the transfer-messenger RNA as the ribosome resumes
translation." Embo J.,
29, 3819-3825. doi: 10.1038/emboj.2010.255.
|
Modified e. coli tmrna in the resume state with the
trna-like domain in the ribosomal p site interacting
with the smpb . SNAP
output
|
|
3izy
|
RNA, ribosomal protein |
cryo-EM (10.8 Å) |
Yassin AS, Haque ME, Datta PP, Elmore K, Banavali NK,
Spremulli LL, Agrawal RK |
(2011) "Insertion
domain within mammalian mitochondrial translation
initiation factor 2 serves the role of eubacterial
initiation factor 1."
Proc.Natl.Acad.Sci.USA, 108,
3918-3923. doi: 10.1073/pnas.1017425108.
|
Mammalian mitochondrial translation initiation factor 2
. SNAP output
|
|
3izz
|
RNA, ribosomal protein |
cryo-EM (10.8 Å) |
Yassin AS, Haque ME, Datta PP, Elmore K, Banavali NK,
Spremulli LL, Agrawal RK |
(2011) "Insertion
domain within mammalian mitochondrial translation
initiation factor 2 serves the role of eubacterial
initiation factor 1."
Proc.Natl.Acad.Sci.USA, 108,
3918-3923. doi: 10.1073/pnas.1017425108.
|
Models for ribosome components that are nearest
neighbors to the bovine mitochondrial initiation
factor2 bound to the e. coli ribosome . SNAP output
|
|
3j06
|
virus |
cryo-EM (3.3 Å) |
Ge P, Zhou ZH |
(2011) "Hydrogen-bonding
networks and RNA bases revealed by cryo electron
microscopy suggest a triggering mechanism for calcium
switches." Proc.Natl.Acad.Sci.USA,
108, 9637-9642. doi: 10.1073/pnas.1018104108.
|
Cryoem helical reconstruction of tmv . SNAP output
|
|
3j0d
|
translation |
cryo-EM (11.1 Å) |
Yokoyama T, Shaikh TR, Iwakura N, Kaji H, Kaji A,
Agrawal RK |
(2012) "Structural
insights into initial and intermediate steps of the
ribosome-recycling process." Embo J.,
31, 1836-1846. doi: 10.1038/emboj.2012.22.
|
Models for the t. thermophilus ribosome recycling
factor bound to the e. coli post-termination complex .
SNAP output
|
|
3j0e
|
translation |
cryo-EM (9.9 Å) |
Yokoyama T, Shaikh TR, Iwakura N, Kaji H, Kaji A,
Agrawal RK |
(2012) "Structural
insights into initial and intermediate steps of the
ribosome-recycling process." Embo J.,
31, 1836-1846. doi: 10.1038/emboj.2012.22.
|
Models for the t. thermophilus ribosome recycling
factor and the e. coli elongation factor g bound to the
e. coli post-termination complex . SNAP output
|
|
3j0l
|
ribosome |
cryo-EM (9.8 Å) |
Budkevich T, Giesebrecht J, Altman RB, Munro JB,
Mielke T, Nierhaus KH, Blanchard SC, Spahn CM |
(2011) "Structure
and dynamics of the Mammalian ribosomal
pretranslocation complex." Mol.Cell,
44, 214-224. doi: 10.1016/j.molcel.2011.07.040.
|
Core of mammalian 80s pre-ribosome in complex with
trnas fitted to a 9.8a cryo-EM map: classic pre state 1
. SNAP output
|
|
3j0o
|
ribosome |
cryo-EM (9.0 Å) |
Budkevich T, Giesebrecht J, Altman RB, Munro JB,
Mielke T, Nierhaus KH, Blanchard SC, Spahn CM |
(2011) "Structure
and dynamics of the Mammalian ribosomal
pretranslocation complex." Mol.Cell,
44, 214-224. doi: 10.1016/j.molcel.2011.07.040.
|
Core of mammalian 80s pre-ribosome in complex with
trnas fitted to a 9a cryo-EM map: classic pre state 2 .
SNAP output
|
|
3j0p
|
ribosome |
cryo-EM (10.6 Å) |
Budkevich T, Giesebrecht J, Altman RB, Munro JB,
Mielke T, Nierhaus KH, Blanchard SC, Spahn CM |
(2011) "Structure
and dynamics of the Mammalian ribosomal
pretranslocation complex." Mol.Cell,
44, 214-224. doi: 10.1016/j.molcel.2011.07.040.
|
Core of mammalian 80s pre-ribosome in complex with
trnas fitted to a 10.6a cryo-EM map: rotated pre state
1 . SNAP output
|
|
3j0q
|
ribosome |
cryo-EM (10.6 Å) |
Budkevich T, Giesebrecht J, Altman RB, Munro JB,
Mielke T, Nierhaus KH, Blanchard SC, Spahn CM |
(2011) "Structure
and dynamics of the Mammalian ribosomal
pretranslocation complex." Mol.Cell,
44, 214-224. doi: 10.1016/j.molcel.2011.07.040.
|
Core of mammalian 80s pre-ribosome in complex with
trnas fitted to a 10.6a cryo-EM map: rotated pre state
2 . SNAP output
|
|
3j16
|
ribosome |
cryo-EM (7.2 Å) |
Becker T, Franckenberg S, Wickles S, Shoemaker CJ,
Anger AM, Armache J-P, Sieber H, Ungewickell C,
Berninghausen O, Daberkow I, Karcher A, Thomm M, Hopfner
KP, Green R, Beckmann R |
(2012) "Structural
basis of highly conserved ribosome recycling in
eukaryotes and archaea." Nature,
482, 501-506. doi: 10.1038/nature10829.
|
Models of ribosome-bound dom34p and rli1p and their
ribosomal binding partners . SNAP output
|
|
3j3v
|
ribosome |
cryo-EM (13.3 Å) |
Li N, Chen Y, Guo Q, Zhang Y, Yuan Y, Ma C, Deng H,
Lei J, Gao N |
(2013) "Cryo-EM
structures of the late-stage assembly intermediates of
the bacterial 50S ribosomal subunit." Nucleic
Acids Res., 41, 7073-7083. doi:
10.1093/nar/gkt423.
|
Atomic model of the immature 50s subunit from bacillus
subtilis (state i-a) . SNAP output
|
|
3j3w
|
ribosome |
cryo-EM (10.7 Å) |
Li N, Chen Y, Guo Q, Zhang Y, Yuan Y, Ma C, Deng H,
Lei J, Gao N |
(2013) "Cryo-EM
structures of the late-stage assembly intermediates of
the bacterial 50S ribosomal subunit." Nucleic
Acids Res., 41, 7073-7083. doi:
10.1093/nar/gkt423.
|
Atomic model of the immature 50s subunit from bacillus
subtilis (state ii-a) . SNAP output
|
|
3j45
|
ribosome-protein transport |
cryo-EM (9.5 Å) |
Park E, Menetret JF, Gumbart JC, Ludtke SJ, Li W,
Whynot A, Rapoport TA, Akey CW |
(2013) "Structure
of the SecY channel during initiation of protein
translocation." Nature,
506, 102-106. doi: 10.1038/nature12720.
|
Structure of a non-translocating secy protein channel
with the 70s ribosome . SNAP output
|
|
3j46
|
ribosome-protein transport |
cryo-EM (10.1 Å) |
Park E, Menetret JF, Gumbart JC, Ludtke SJ, Li W,
Whynot A, Rapoport TA, Akey CW |
(2013) "Structure
of the SecY channel during initiation of protein
translocation." Nature,
506, 102-106. doi: 10.1038/nature12720.
|
Structure of the secy protein translocation channel in
action . SNAP output
|
|
3j5l
|
ribosome-antibiotic |
cryo-EM (6.6 Å) |
Arenz S, Ramu H, Gupta P, Berninghausen O, Beckmann
R, Vazquez-Laslop N, Mankin AS, Wilson DN |
(2014) "Molecular
basis for erythromycin-dependent ribosome stalling
during translation of the ErmBL leader peptide."
Nat Commun, 5, 3501. doi:
10.1038/ncomms4501.
|
Structure of the e. coli 50s subunit with ermbl nascent
chain . SNAP output
|
|
3j5s
|
ribosome-translation |
cryo-EM (7.5 Å) |
Chen B, Boel G, Hashem Y, Ning W, Fei J, Wang C,
Gonzalez RL, Hunt JF, Frank J |
(2014) "EttA
regulates translation by binding the ribosomal E site
and restricting ribosome-tRNA dynamics."
Nat.Struct.Mol.Biol., 21,
152-159. doi: 10.1038/nsmb.2741.
|
Etta binds to ribosome exit site and regulates
translation by restricting ribosome and trna dynamics .
SNAP output
|
|
3j5y
|
translation-RNA |
cryo-EM (9.7 Å) |
des Georges A, Hashem Y, Unbehaun A, Grassucci RA,
Taylor D, Hellen CU, Pestova TV, Frank J |
(2014) "Structure
of the mammalian ribosomal pre-termination complex
associated with eRF1*eRF3*GDPNP." Nucleic Acids
Res., 42, 3409-3418. doi:
10.1093/nar/gkt1279.
|
Structure of the mammalian ribosomal pre-termination
complex associated with erf1-erf3-gdpnp . SNAP output
|
|
3j6b
|
ribosome |
cryo-EM (3.2 Å) |
Amunts A, Brown A, Bai XC, Llacer JL, Hussain T,
Emsley P, Long F, Murshudov G, Scheres SH, Ramakrishnan
V |
(2014) "Structure
of the yeast mitochondrial large ribosomal
subunit." Science, 343,
1485-1489. doi: 10.1126/science.1249410.
|
Structure of the yeast mitochondrial large ribosomal
subunit . SNAP
output
|
|
3j77
|
ribosome |
cryo-EM (6.2 Å) |
Svidritskiy E, Brilot AF, Koh CS, Grigorieff N,
Korostelev AA |
(2014) "Structures
of Yeast 80S Ribosome-tRNA Complexes in the Rotated and
Nonrotated Conformations." Structure,
22, 1210-1218. doi: 10.1016/j.str.2014.06.003.
|
Structures of yeast 80s ribosome-trna complexes in the
rotated and non-rotated conformations (class ii -
rotated ribosome with 1 trna) . SNAP output
|
|
3j78
|
ribosome |
cryo-EM (6.3 Å) |
Svidritskiy E, Brilot AF, Koh CS, Grigorieff N,
Korostelev AA |
(2014) "Structures
of Yeast 80S Ribosome-tRNA Complexes in the Rotated and
Nonrotated Conformations." Structure,
22, 1210-1218. doi: 10.1016/j.str.2014.06.003.
|
Structures of yeast 80s ribosome-trna complexes in the
rotated and non-rotated conformations (class i -
non-rotated ribosome with 2 trnas) . SNAP output
|
|
3j79
|
ribosome-inhibitor |
cryo-EM (3.2 Å) |
Wong W, Bai XC, Brown A, Fernandez IS, Hanssen E,
Condron M, Tan YH, Baum J, Scheres SH |
(2014) "Cryo-EM
structure of the Plasmodium falciparum 80S ribosome
bound to the anti-protozoan drug emetine."
Elife, 3, e03080. doi:
10.7554/eLife.03080.
|
cryo-EM structure of the plasmodium falciparum 80s
ribosome bound to the anti-protozoan drug emetine,
large subunit . SNAP
output
|
|
3j7a
|
ribosome-inhibitor |
cryo-EM (3.2 Å) |
Wong W, Bai XC, Brown A, Fernandez IS, Hanssen E,
Condron M, Tan YH, Baum J, Scheres SH |
(2014) "Cryo-EM
structure of the Plasmodium falciparum 80S ribosome
bound to the anti-protozoan drug emetine."
Elife, 3, e03080. doi:
10.7554/eLife.03080.
|
cryo-EM structure of the plasmodium falciparum 80s
ribosome bound to the anti-protozoan drug emetine,
small subunit . SNAP
output
|
|
3j7y
|
ribosome |
cryo-EM (3.4 Å) |
Brown A, Amunts A, Bai XC, Sugimoto Y, Edwards PC,
Murshudov G, Scheres SH, Ramakrishnan V |
(2014) "Structure
of the large ribosomal subunit from human
mitochondria." Science,
346, 718-722. doi: 10.1126/science.1258026.
|
Structure of the large ribosomal subunit from human
mitochondria . SNAP
output
|
|
3j7z
|
ribosome-antibiotic |
cryo-EM (3.9 Å) |
Arenz S, Meydan S, Starosta AL, Berninghausen O,
Beckmann R, Vazquez-Laslop N, Wilson DN |
(2014) "Drug
Sensing by the Ribosome Induces Translational Arrest
via Active Site Perturbation." Mol.Cell,
56, 446-452. doi: 10.1016/j.molcel.2014.09.014.
|
Structure of the e. coli 50s subunit with ermcl nascent
chain . SNAP output
|
|
3j80
|
ribosome |
cryo-EM (3.75 Å) |
Hussain T, Llacer JL, Fernandez IS, Munoz A,
Martin-Marcos P, Savva CG, Lorsch JR, Hinnebusch AG,
Ramakrishnan V |
(2014) "Structural
changes enable start codon recognition by the
eukaryotic translation initiation complex."
Cell(Cambridge,Mass.), 159,
597-607. doi: 10.1016/j.cell.2014.10.001.
|
Cryoem structure of 40s-eif1-eif1a preinitiation
complex . SNAP
output
|
|
3j81
|
ribosome |
cryo-EM (4.0 Å) |
Hussain T, Llacer JL, Fernandez IS, Munoz A,
Martin-Marcos P, Savva CG, Lorsch JR, Hinnebusch AG,
Ramakrishnan V |
(2014) "Structural
changes enable start codon recognition by the
eukaryotic translation initiation complex."
Cell(Cambridge,Mass.), 159,
597-607. doi: 10.1016/j.cell.2014.10.001.
|
Cryoem structure of a partial yeast 48s preinitiation
complex . SNAP
output
|
|
3j8g
|
ribosome |
cryo-EM (5.0 Å) |
Zhang X, Yan K, Zhang Y, Li N, Ma C, Li Z, Zhang Y,
Feng B, Liu J, Sun Y, Xu Y, Lei J, Gao N |
(2014) "Structural
insights into the function of a unique tandem GTPase
EngA in bacterial ribosome assembly." Nucleic
Acids Res. doi: 10.1093/nar/gku1135.
|
Electron cryo-microscopy structure of enga bound with
the 50s ribosomal subunit . SNAP output
|
|
3j9b
|
RNA binding protein-transferase-RNA |
cryo-EM (4.3 Å) |
Chang S, Sun D, Liang H, Wang J, Li J, Guo L, Wang X,
Guan C, Boruah BM, Yuan L, Feng F, Yang M, Wang L, Wang
Y, Wojdyla J, Li L, Wang J, Wang M, Cheng G, Wang HW, Liu
Y |
(2015) "Cryo-EM
Structure of Influenza Virus RNA Polymerase Complex at
4.3 angstrom Resolution." Mol.Cell. doi:
10.1016/j.molcel.2014.12.031.
|
Electron cryo-microscopy of an RNA polymerase .
SNAP output
|
|
3j9m
|
ribosome |
cryo-EM (3.5 Å) |
Amunts A, Brown A, Toots J, Scheres SH, Ramakrishnan
V |
(2015) "Ribosome.
The structure of the human mitochondrial ribosome."
Science, 348, 95-98. doi:
10.1126/science.aaa1193.
|
Structure of the human mitochondrial ribosome (class 1)
. SNAP output
|
|
3j9w
|
ribosome |
cryo-EM (3.9 Å) |
Sohmen D, Chiba S, Shimokawa-Chiba N, Innis CA,
Berninghausen O, Beckmann R, Ito K, Wilson DN |
(2015) "Structure
of the Bacillus subtilis 70S ribosome reveals the basis
for species-specific stalling." Nat
Commun, 6, 6941. doi: 10.1038/ncomms7941.
|
cryo-EM structure of the bacillus subtilis mifm-stalled
ribosome complex . SNAP
output
|
|
3j9y
|
ribosome |
cryo-EM (3.9 Å) |
Arenz S, Nguyen F, Beckmann R, Wilson DN |
(2015) "Cryo-EM
structure of the tetracycline resistance protein TetM
in complex with a translating ribosome at 3.9- angstrom
resolution." Proc.Natl.Acad.Sci.USA,
112, 5401-5406. doi: 10.1073/pnas.1501775112.
|
cryo-EM structure of tetracycline resistance protein
tetm bound to a translating e.coli ribosome . SNAP output
|
|
3j9z
|
ribosome |
cryo-EM (3.6 Å) |
Li W, Liu Z, Koripella RK, Langlois R, Sanyal S,
Frank J |
(2015) "Activation
of GTP hydrolysis in mRNA-tRNA translocation by
elongation factor G." Sci Adv,
1, e1500169. doi: 10.1126/sciadv.1500169.
|
Activation of gtp hydrolysis in mrna-trna translocation
by elongation factor g . SNAP output
|
|
3ja1
|
ribosome |
cryo-EM (3.6 Å) |
Li W, Liu Z, Koripella RK, Langlois R, Sanyal S,
Frank J |
(2015) "Activation
of GTP hydrolysis in mRNA-tRNA translocation by
elongation factor G." Sci Adv,
1, e1500169. doi: 10.1126/sciadv.1500169.
|
Activation of gtp hydrolysis in mrna-trna translocation
by elongation factor g . SNAP output
|
|
3jam
|
translation |
cryo-EM (3.46 Å) |
Llacer JL, Hussain T, Marler L, Aitken CE, Thakur A,
Lorsch JR, Hinnebusch AG, Ramakrishnan V |
(2015) "Conformational
Differences between Open and Closed States of the
Eukaryotic Translation Initiation Complex."
Mol.Cell, 59, 399-412. doi:
10.1016/j.molcel.2015.06.033.
|
Cryoem structure of 40s-eif1a-eif1 complex from yeast .
SNAP output
|
|
3jap
|
translation |
cryo-EM (4.9 Å) |
Llacer JL, Hussain T, Marler L, Aitken CE, Thakur A,
Lorsch JR, Hinnebusch AG, Ramakrishnan V |
(2015) "Conformational
Differences between Open and Closed States of the
Eukaryotic Translation Initiation Complex."
Mol.Cell, 59, 399-412. doi:
10.1016/j.molcel.2015.06.033.
|
Structure of a partial yeast 48s preinitiation complex
in closed conformation . SNAP output
|
|
3jb7
|
transferase-viral protein-RNA |
cryo-EM (4.0 Å) |
Zhang X, Ding K, Yu X, Chang W, Sun J, Hong Zhou
Z |
(2015) "In situ
structures of the segmented genome and RNA polymerase
complex inside a dsRNA virus." Nature,
527, 531-534. doi: 10.1038/nature15767.
|
In situ structures of the segmented genome and RNA
polymerase complex inside a dsrna virus . SNAP output
|
|
3jb9
|
RNA binding protein-RNA |
cryo-EM (3.6 Å) |
Yan C, Hang J, Wan R, Huang M, Wong C, Shi Y |
(2015) "Structure
of a yeast spliceosome at 3.6-angstrom resolution."
Science, 349, 1182-1191. doi:
10.1126/science.aac7629.
|
cryo-EM structure of the yeast spliceosome at 3.6
angstrom resolution . SNAP output
|
|
3jbn
|
ribosome |
cryo-EM (4.7 Å) |
Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD,
Frank J |
(2015) "Dynamical
features of the Plasmodium falciparum ribosome during
translation." Nucleic Acids Res.,
43, 10515-10524. doi: 10.1093/nar/gkv991.
|
Cryo-electron microscopy reconstruction of the
plasmodium falciparum 80s ribosome bound to p-trna .
SNAP output
|
|
3jbo
|
ribosome |
cryo-EM (5.8 Å) |
Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD,
Frank J |
(2015) "Dynamical
features of the Plasmodium falciparum ribosome during
translation." Nucleic Acids Res.,
43, 10515-10524. doi: 10.1093/nar/gkv991.
|
Cryo-electron microscopy reconstruction of the
plasmodium falciparum 80s ribosome bound to p-e-trna .
SNAP output
|
|
3jbp
|
ribosome |
cryo-EM (6.7 Å) |
Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD,
Frank J |
(2015) "Dynamical
features of the Plasmodium falciparum ribosome during
translation." Nucleic Acids Res.,
43, 10515-10524. doi: 10.1093/nar/gkv991.
|
Cryo-electron microscopy reconstruction of the
plasmodium falciparum 80s ribosome bound to e-trna .
SNAP output
|
|
3jbu
|
ribosome |
cryo-EM (3.64 Å) |
Zhang J, Pan X, Yan K, Sun S, Gao N, Sui SF |
(2015) "Mechanisms
of ribosome stalling by SecM at multiple elongation
steps." Elife, 4. doi:
10.7554/eLife.09684.
|
Mechanisms of ribosome stalling by secm at multiple
elongation steps . SNAP
output
|
|
3jbv
|
ribosome |
cryo-EM (3.32 Å) |
Zhang J, Pan X, Yan K, Sun S, Gao N, Sui SF |
(2015) "Mechanisms
of ribosome stalling by SecM at multiple elongation
steps." Elife, 4. doi:
10.7554/eLife.09684.
|
Mechanisms of ribosome stalling by secm at multiple
elongation steps . SNAP
output
|
|
3jcd
|
ribosome |
cryo-EM (3.7 Å) |
Zhang D, Yan K, Liu G, Song G, Luo J, Shi Y, Cheng E,
Wu S, Jiang T, Lou J, Gao N, Qin Y |
(2016) "EF4
disengages the peptidyl-tRNA CCA end and facilitates
back-translocation on the 70S ribosome." Nat.
Struct. Mol. Biol., 23, 125-131.
doi: 10.1038/nsmb.3160.
|
Structure of escherichia coli ef4 in
posttranslocational ribosomes (post ef4) . SNAP output
|
|
3jce
|
ribosome |
cryo-EM (3.2 Å) |
Zhang D, Yan K, Liu G, Song G, Luo J, Shi Y, Cheng E,
Wu S, Jiang T, Lou J, Gao N, Qin Y |
(2016) "EF4
disengages the peptidyl-tRNA CCA end and facilitates
back-translocation on the 70S ribosome." Nat.
Struct. Mol. Biol., 23, 125-131.
doi: 10.1038/nsmb.3160.
|
Structure of escherichia coli ef4 in pretranslocational
ribosomes (pre ef4) . SNAP output
|
|
3jcj
|
ribosome |
cryo-EM (3.7 Å) |
Sprink T, Ramrath DJ, Yamamoto H, Yamamoto K, Loerke
J, Ismer J, Hildebrand PW, Scheerer P, Burger J, Mielke
T, Spahn CM |
(2016) "Structures
of ribosome-bound initiation factor 2 reveal the
mechanism of subunit association." Sci
Adv, 2, e1501502. doi: 10.1126/sciadv.1501502.
|
Structures of ribosome-bound initiation factor 2 reveal
the mechanism of subunit association . SNAP output
|
|
3jcm
|
transcription |
cryo-EM (3.8 Å) |
Wan R, Yan C, Bai R, Wang L, Huang M, Wong CC, Shi
Y |
(2016) "The 3.8
angstrom structure of the U4/U6.U5 tri-snRNP: Insights
into spliceosome assembly and catalysis."
Science, 351, 466-475. doi:
10.1126/science.aad6466.
|
cryo-EM structure of the spliceosomal u4-u6.u5
tri-snrnp . SNAP
output
|
|
3jcn
|
ribosome |
cryo-EM (4.6 Å) |
Sprink T, Ramrath DJ, Yamamoto H, Yamamoto K, Loerke
J, Ismer J, Hildebrand PW, Scheerer P, Burger J, Mielke
T, Spahn CM |
(2016) "Structures
of ribosome-bound initiation factor 2 reveal the
mechanism of subunit association." Sci
Adv, 2, e1501502. doi: 10.1126/sciadv.1501502.
|
Structures of ribosome-bound initiation factor 2 reveal
the mechanism of subunit association: initiation
complex i . SNAP
output
|
|
3jcs
|
ribosome |
cryo-EM (2.8 Å) |
Shalev-Benami M, Zhang Y, Matzov D, Halfon Y, Zackay
A, Rozenberg H, Zimmerman E, Bashan A, Jaffe CL, Yonath
A, Skiniotis G |
(2016) "2.8-
angstrom Cryo-EM Structure of the Large Ribosomal
Subunit from the Eukaryotic Parasite Leishmania."
Cell Rep, 16, 288-294. doi:
10.1016/j.celrep.2016.06.014.
|
2.8 angstrom cryo-EM structure of the large ribosomal
subunit from the eukaryotic parasite leishmania .
SNAP output
|
|
3jct
|
ribosome |
cryo-EM (3.08 Å) |
Wu S, Tutuncuoglu B, Yan K, Brown H, Zhang Y, Tan D,
Gamalinda M, Yuan Y, Li Z, Jakovljevic J, Ma C, Lei J,
Dong MQ, Woolford JL, Gao N |
(2016) "Diverse
roles of assembly factors revealed by structures of
late nuclear pre-60S ribosomes." Nature,
534, 133-137. doi: 10.1038/nature17942.
|
cryo-EM structure of eukaryotic pre-60s ribosomal
subunits . SNAP
output
|
|
3jd5
|
ribosome |
cryo-EM (7.0 Å) |
Kaushal PS, Sharma MR, Booth TM, Haque EM, Tung CS,
Sanbonmatsu KY, Spremulli LL, Agrawal RK |
(2014) "Cryo-EM
structure of the small subunit of the mammalian
mitochondrial ribosome."
Proc.Natl.Acad.Sci.USA, 111,
7284-7289. doi: 10.1073/pnas.1401657111.
|
cryo-EM structure of the small subunit of the mammalian
mitochondrial ribosome . SNAP output
|
|
3k0j
|
RNA-RNA binding protein |
X-ray (3.1 Å) |
Kulshina N, Edwards TE, Ferre-D'Amare AR |
(2010) "Thermodynamic
analysis of ligand binding and ligand binding-induced
tertiary structure formation by the thiamine
pyrophosphate riboswitch." Rna,
16, 186-196. doi: 10.1261/rna.1847310.
|
Crystal structure of the e. coli thim riboswitch in
complex with thiamine pyrophosphate and the u1a
crystallization module . SNAP output
|
|
3k49
|
RNA binding protein - RNA |
X-ray (2.5 Å) |
Zhu D, Stumpf CR, Krahn JM, Wickens M, Hall TM |
(2009) "A 5'
cytosine binding pocket in Puf3p specifies regulation
of mitochondrial mRNAs."
Proc.Natl.Acad.Sci.USA, 106,
20192-20197. doi: 10.1073/pnas.0812079106.
|
Puf3 RNA binding domain bound to cox17 RNA 3' utr
recognition sequence site b . SNAP output
|
|
3k4e
|
RNA binding protein - RNA |
X-ray (3.2 Å) |
Zhu D, Stumpf CR, Krahn JM, Wickens M, Hall TM |
(2009) "A 5'
cytosine binding pocket in Puf3p specifies regulation
of mitochondrial mRNAs."
Proc.Natl.Acad.Sci.USA, 106,
20192-20197. doi: 10.1073/pnas.0812079106.
|
Puf3 RNA binding domain bound to cox17 RNA 3' utr
recognition sequence site a . SNAP output
|
|
3k5q
|
RNA-RNA binding protein |
X-ray (2.2 Å) |
Wang Y, Opperman L, Wickens M, Hall TM |
(2009) "Structural
basis for specific recognition of multiple mRNA targets
by a PUF regulatory protein."
Proc.Natl.Acad.Sci.USA, 106,
20186-20191. doi: 10.1073/pnas.0812076106.
|
Crystal structure of fbf-2-fbe complex . SNAP output
|
|
3k5y
|
RNA-RNA binding protein |
X-ray (2.3 Å) |
Wang Y, Opperman L, Wickens M, Hall TM |
(2009) "Structural
basis for specific recognition of multiple mRNA targets
by a PUF regulatory protein."
Proc.Natl.Acad.Sci.USA, 106,
20186-20191. doi: 10.1073/pnas.0812076106.
|
Crystal structure of fbf-2-gld-1 fbea complex .
SNAP output
|
|
3k5z
|
RNA-RNA binding protein |
X-ray (2.4 Å) |
Wang Y, Opperman L, Wickens M, Hall TM |
(2009) "Structural
basis for specific recognition of multiple mRNA targets
by a PUF regulatory protein."
Proc.Natl.Acad.Sci.USA, 106,
20186-20191. doi: 10.1073/pnas.0812076106.
|
Crystal structure of fbf-2-gld-1 fbea g4a mutant
complex . SNAP
output
|
|
3k61
|
RNA-RNA binding protein |
X-ray (2.21 Å) |
Wang Y, Opperman L, Wickens M, Hall TM |
(2009) "Structural
basis for specific recognition of multiple mRNA targets
by a PUF regulatory protein."
Proc.Natl.Acad.Sci.USA, 106,
20186-20191. doi: 10.1073/pnas.0812076106.
|
Crystal structure of fbf-2-fog-1 fbea complex .
SNAP output
|
|
3k62
|
RNA-RNA binding protein |
X-ray (1.9 Å) |
Wang Y, Opperman L, Wickens M, Hall TM |
(2009) "Structural
basis for specific recognition of multiple mRNA targets
by a PUF regulatory protein."
Proc.Natl.Acad.Sci.USA, 106,
20186-20191. doi: 10.1073/pnas.0812076106.
|
Crystal structure of fbf-2-gld-1 fbeb complex .
SNAP output
|
|
3k64
|
RNA-RNA binding protein |
X-ray (2.0 Å) |
Wang Y, Opperman L, Wickens M, Hall TM |
(2009) "Structural
basis for specific recognition of multiple mRNA targets
by a PUF regulatory protein."
Proc.Natl.Acad.Sci.USA, 106,
20186-20191. doi: 10.1073/pnas.0812076106.
|
Crystal structure of fbf-2-fem-3 pme complex . SNAP output
|
|
3kfu
|
ligase-RNA |
X-ray (3.0 Å) |
Blaise M, Bailly M, Frechin M, Behrens MA, Fischer F,
Oliveira CL, Becker HD, Pedersen JS, Thirup S, Kern
D |
(2010) "Crystal
structure of a transfer-ribonucleoprotein particle that
promotes asparagine formation." Embo J.,
29, 3118-3129. doi: 10.1038/emboj.2010.192.
|
Crystal structure of the transamidosome . SNAP output
|
|
3klv
|
transferase-RNA |
X-ray (2.6 Å) |
Ferrer-Orta C, Sierra M, Agudo R, de la Higuera I,
Arias A, Perez-Luque R, Escarmis C, Domingo E, Verdaguer
N |
(2010) "Structure
of foot-and-mouth disease virus mutant polymerases with
reduced sensitivity to ribavirin."
J.Virol., 84, 6188-6199. doi:
10.1128/JVI.02420-09.
|
M296i g62s mutant of foot-and-mouth disease virus
RNA-polymerase in complex with a template- primer RNA .
SNAP output
|
|
3kmq
|
transferase-RNA |
X-ray (2.11 Å) |
Ferrer-Orta C, Sierra M, Agudo R, de la Higuera I,
Arias A, Perez-Luque R, Escarmis C, Domingo E, Verdaguer
N |
(2010) "Structure
of foot-and-mouth disease virus mutant polymerases with
reduced sensitivity to ribavirin."
J.Virol., 84, 6188-6199. doi:
10.1128/JVI.02420-09.
|
G62s mutant of foot-and-mouth disease virus
RNA-polymerase in complex with a template- primer RNA,
tetragonal structure . SNAP output
|
|
3kms
|
transferase-RNA |
X-ray (2.2 Å) |
Ferrer-Orta C, Sierra M, Agudo R, de la Higuera I,
Arias A, Perez-Luque R, Escarmis C, Domingo E, Verdaguer
N |
(2010) "Structure
of foot-and-mouth disease virus mutant polymerases with
reduced sensitivity to ribavirin."
J.Virol., 84, 6188-6199. doi:
10.1128/JVI.02420-09.
|
G62s mutant of foot-and-mouth disease virus
RNA-polymerase in complex with a template- primer RNA
trigonal structure . SNAP output
|
|
3kna
|
transferase-RNA |
X-ray (2.8 Å) |
Ferrer-Orta C, Sierra M, Agudo R, de la Higuera I,
Arias A, Perez-Luque R, Escarmis C, Domingo E, Verdaguer
N |
(2010) "Structure
of foot-and-mouth disease virus mutant polymerases with
reduced sensitivity to ribavirin."
J.Virol., 84, 6188-6199. doi:
10.1128/JVI.02420-09.
|
M296i mutant of foot-and-mouth disease virus
RNA-polymerase in complex with a template- primer RNA .
SNAP output
|
|
3koa
|
transferase-RNA |
X-ray (2.4 Å) |
Ferrer-Orta C, Sierra M, Agudo R, de la Higuera I,
Arias A, Perez-Luque R, Escarmis C, Domingo E, Verdaguer
N |
(2010) "Structure
of foot-and-mouth disease virus mutant polymerases with
reduced sensitivity to ribavirin."
J.Virol., 84, 6188-6199. doi:
10.1128/JVI.02420-09.
|
M296i mutant of foot-and-mouth disease virus
RNA-polymerase in complex with a template- primer RNA
and gtp . SNAP
output
|
|
3ks8
|
viral protein-RNA |
X-ray (2.401 Å) |
Kimberlin CR, Bornholdt ZA, Li S, Woods VL, Macrae
IJ, Saphire EO |
(2009) "Ebolavirus
VP35 uses a bimodal strategy to bind dsRNA for innate
immune suppression."
Proc.Natl.Acad.Sci.USA, 107,
314-319. doi: 10.1073/pnas.0910547107.
|
Crystal structure of reston ebolavirus vp35 RNA binding
domain in complex with 18bp dsrna . SNAP output
|
|
3ktv
|
RNA-RNA binding protein |
X-ray (3.8 Å) |
Wild K, Bange G, Bozkurt G, Segnitz B, Hendricks A,
Sinning I |
(2010) "Structural
insights into the assembly of the human and archaeal
signal recognition particles." Acta
Crystallogr.,Sect.D, 66, 295-303.
doi: 10.1107/S0907444910000879.
|
Crystal structure of the human srp19-s-domain srp RNA
complex . SNAP
output
|
|
3ktw
|
RNA-RNA binding protein |
X-ray (3.2 Å) |
Wild K, Bange G, Bozkurt G, Segnitz B, Hendricks A,
Sinning I |
(2010) "Structural
insights into the assembly of the human and archaeal
signal recognition particles." Acta
Crystallogr.,Sect.D, 66, 295-303.
doi: 10.1107/S0907444910000879.
|
Crystal structure of the srp19-s-domain srp RNA complex
of sulfolobus solfataricus . SNAP output
|
|
3l25
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Leung DW, Prins KC, Borek DM, Farahbakhsh M,
Tufariello JM, Ramanan P, Nix JC, Helgeson LA, Otwinowski
Z, Honzatko RB, Basler CF, Amarasinghe GK |
(2010) "Structural
basis for dsRNA recognition and interferon antagonism
by Ebola VP35." Nat.Struct.Mol.Biol.,
17, 165-172. doi: 10.1038/nsmb.1765.
|
Crystal structure of zaire ebola vp35 interferon
inhibitory domain bound to 8 bp dsrna . SNAP output
|
|
3l26
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Leung DW, Prins KC, Borek DM, Farahbakhsh M,
Tufariello JM, Ramanan P, Nix JC, Helgeson LA, Otwinowski
Z, Honzatko RB, Basler CF, Amarasinghe GK |
(2010) "Structural
basis for dsRNA recognition and interferon antagonism
by Ebola VP35." Nat.Struct.Mol.Biol.,
17, 165-172. doi: 10.1038/nsmb.1765.
|
Crystal structure of zaire ebola vp35 interferon
inhibitory domain bound to 8 bp dsrna . SNAP output
|
|
3l3c
|
RNA binding protein-RNA |
X-ray (2.85 Å) |
Cochrane JC, Lipchock SV, Smith KD, Strobel SA |
(2009) "Structural
and chemical basis for glucosamine 6-phosphate binding
and activation of the glmS ribozyme."
Biochemistry, 48, 3239-3246.
doi: 10.1021/bi802069p.
|
Crystal structure of the bacillus anthracis glms
ribozyme bound to glc6p . SNAP output
|
|
3lob
|
virus |
X-ray (3.6 Å) |
Banerjee M, Speir JA, Kwan MH, Huang R, Aryanpur PP,
Bothner B, Johnson JE |
(2010) "Structure
and function of a genetically engineered mimic of a
nonenveloped virus entry intermediate."
J.Virol., 84, 4737-4746. doi:
10.1128/JVI.02670-09.
|
Crystal structure of flock house virus calcium mutant .
SNAP output
|
|
3lqx
|
RNA-RNA binding protein |
X-ray (1.93 Å) |
Batey RT, Doudna JA |
(2002) "Structural
and Energetic Analysis of Metal Ions Essential to SRP
Signal Recognition Domain Assembly."
Biochemistry, 41,
11703-11710.
|
Srp ribonucleoprotein core complexed with cobalt
hexammine . SNAP
output
|
|
3lrn
|
hydrolase-RNA |
X-ray (2.6 Å) |
Lu C, Xu H, Ranjith-Kumar CT, Brooks MT, Hou TY, Hu
F, Herr AB, Strong RK, Kao CC, Li P |
(2010) "The
Structural Basis of 5' Triphosphate Double-Stranded RNA
Recognition by RIG-I C-Terminal Domain."
Structure, 18, 1032-1043.
doi: 10.1016/j.str.2010.05.007.
|
Crystal structure of human rig-i ctd bound to a 14 bp
gc 5' ppp dsrna . SNAP
output
|
|
3lrr
|
hydrolase-RNA |
X-ray (2.15 Å) |
Lu C, Xu H, Ranjith-Kumar CT, Brooks MT, Hou TY, Hu
F, Herr AB, Strong RK, Kao CC, Li P |
(2010) "The
Structural Basis of 5' Triphosphate Double-Stranded RNA
Recognition by RIG-I C-Terminal Domain."
Structure, 18, 1032-1043.
doi: 10.1016/j.str.2010.05.007.
|
Crystal structure of human rig-i ctd bound to a 12 bp
au rich 5' ppp dsrna . SNAP output
|
|
3lwo
|
isomerase-RNA binding protein-RNA |
X-ray (2.855 Å) |
Zhou J, Lv C, Liang B, Chen M, Yang W, Li H |
(2010) "Glycosidic
bond conformation preference plays a pivotal role in
catalysis of RNA pseudouridylation: a combined
simulation and structural study."
J.Mol.Biol., 401, 690-695.
doi: 10.1016/j.jmb.2010.06.061.
|
Structure of h-aca rnp bound to a substrate RNA
containing 5bru . SNAP
output
|
|
3lwp
|
isomerase-RNA binding protein-RNA |
X-ray (2.5 Å) |
Zhou J, Lv C, Liang B, Chen M, Yang W, Li H |
(2010) "Glycosidic
bond conformation preference plays a pivotal role in
catalysis of RNA pseudouridylation: a combined
simulation and structural study."
J.Mol.Biol., 401, 690-695.
doi: 10.1016/j.jmb.2010.06.061.
|
Structure of h-aca rnp bound to a substrate RNA
containing 5brdu . SNAP
output
|
|
3lwq
|
isomerase-RNA binding protein-RNA |
X-ray (2.678 Å) |
Zhou J, Liang B, Li H |
(2010) "Functional
and Structural Impact of Target Uridine Substitutions
on the H/ACA Ribonucleoprotein Particle Pseudouridine
Synthase ." Biochemistry,
49, 6276-6281. doi: 10.1021/bi1006699.
|
Structure of h-aca rnp bound to a substrate RNA
containing 3mu . SNAP
output
|
|
3lwr
|
isomerase-RNA binding protein-RNA |
X-ray (2.203 Å) |
Zhou J, Liang B, Li H |
(2010) "Functional
and Structural Impact of Target Uridine Substitutions
on the H/ACA Ribonucleoprotein Particle Pseudouridine
Synthase ." Biochemistry,
49, 6276-6281. doi: 10.1021/bi1006699.
|
Structure of h-aca rnp bound to a substrate RNA
containing 4su . SNAP
output
|
|
3lwv
|
isomerase-RNA binding protein-RNA |
X-ray (2.499 Å) |
Zhou J, Liang B, Li H |
(2010) "Functional
and Structural Impact of Target Uridine Substitutions
on the H/ACA Ribonucleoprotein Particle Pseudouridine
Synthase ." Biochemistry,
49, 6276-6281. doi: 10.1021/bi1006699.
|
Structure of h-aca rnp bound to a substrate RNA
containing 2'-deoxyuridine . SNAP output
|
|
3m7n
|
hydrolase-RNA |
X-ray (2.4 Å) |
Hartung S, Niederberger T, Hartung M, Tresch A,
Hopfner K-P |
(2010) "Quantitative
analysis of processive RNA degradation by the archaeal
RNA exosome." Nucleic Acids Res.,
38, 5166-5176. doi: 10.1093/nar/gkq238.
|
Archaeoglobus fulgidus exosome with RNA bound to the
active site . SNAP
output
|
|
3m85
|
hydrolase-RNA |
X-ray (3.0 Å) |
Hartung S, Niederberger T, Hartung M, Tresch A,
Hopfner K-P |
(2010) "Quantitative
analysis of processive RNA degradation by the archaeal
RNA exosome." Nucleic Acids Res.,
38, 5166-5176. doi: 10.1093/nar/gkq238.
|
Archaeoglobus fulgidus exosome y70a with RNA bound to
the active site . SNAP
output
|
|
3mdg
|
RNA binding-RNA |
X-ray (2.22 Å) |
Yang Q, Gilmartin GM, Doublie S |
(2010) "Structural
basis of UGUA recognition by the Nudix protein CFI(m)25
and implications for a regulatory role in mRNA 3'
processing." Proc.Natl.Acad.Sci.USA,
107, 10062-10067. doi: 10.1073/pnas.1000848107.
|
Crystal structure of the 25kda subunit of human
cleavage factor im in complex with RNA uuguau .
SNAP output
|
|
3mdi
|
RNA binding-RNA |
X-ray (2.07 Å) |
Yang Q, Gilmartin GM, Doublie S |
(2010) "Structural
basis of UGUA recognition by the Nudix protein CFI(m)25
and implications for a regulatory role in mRNA 3'
processing." Proc.Natl.Acad.Sci.USA,
107, 10062-10067. doi: 10.1073/pnas.1000848107.
|
Crystal structure of the 25kda subunit of human
cleavage factor im in complex with RNA uguaaa .
SNAP output
|
|
3mj0
|
RNA-RNA binding protein |
X-ray (2.306 Å) |
Huang Y, Ding L, Ma J |
"Crystal Structure of drosophila Ago2 PAZ domain in
complex with 3'-end 2'-O-methylated RNA." |
Crystal structure of drosophia ago-paz domain in
complex with 3'-end 2'-o-methylated RNA . SNAP output
|
|
3moj
|
RNA binding protein-RNA |
X-ray (2.902 Å) |
Hardin JW, Hu YX, McKay DB |
(2010) "Structure
of the RNA binding domain of a DEAD-box helicase bound
to its ribosomal RNA target reveals a novel mode of
recognition by an RNA recognition motif."
J.Mol.Biol., 402, 412-427.
doi: 10.1016/j.jmb.2010.07.040.
|
Structure of the RNA binding domain of the bacillus
subtilis yxin protein complexed with a fragment of 23s
ribosomal RNA . SNAP
output
|
|
3mqk
|
isomerase-RNA binding protein-RNA |
X-ray (2.8 Å) |
Zhou J, Liang B, Li H |
(2011) "Structural
and functional evidence of high specificity of Cbf5 for
ACA trinucleotide." Rna,
17, 244-250. doi: 10.1261/rna.2415811.
|
Cbf5-nop10-gar1 complex binding with 17mer RNA
containing aca trinucleotide . SNAP output
|
|
3mum
|
RNA binding protein-RNA |
X-ray (2.9 Å) |
Smith KD, Lipchock SV, Livingston AL, Shanahan CA,
Strobel SA |
(2010) "Structural
and biochemical determinants of ligand binding by the
c-di-GMP riboswitch ." Biochemistry,
49, 7351-7359. doi: 10.1021/bi100671e.
|
Crystal structure of the g20a mutant c-di-gmp riboswith
bound to c-di-gmp . SNAP
output
|
|
3mur
|
RNA binding protein-RNA |
X-ray (3.0 Å) |
Smith KD, Lipchock SV, Livingston AL, Shanahan CA,
Strobel SA |
(2010) "Structural
and biochemical determinants of ligand binding by the
c-di-GMP riboswitch ." Biochemistry,
49, 7351-7359. doi: 10.1021/bi100671e.
|
Crystal structure of the c92u mutant c-di-gmp riboswith
bound to c-di-gmp . SNAP
output
|
|
3mut
|
RNA binding protein-RNA |
X-ray (3.0 Å) |
Smith KD, Lipchock SV, Livingston AL, Shanahan CA,
Strobel SA |
(2010) "Structural
and biochemical determinants of ligand binding by the
c-di-GMP riboswitch ." Biochemistry,
49, 7351-7359. doi: 10.1021/bi100671e.
|
Crystal structure of the g20a-c92u mutant c-di-gmp
riboswith bound to c-di-gmp . SNAP output
|
|
3muv
|
RNA binding protein-RNA |
X-ray (3.2 Å) |
Smith KD, Lipchock SV, Livingston AL, Shanahan CA,
Strobel SA |
(2010) "Structural
and biochemical determinants of ligand binding by the
c-di-GMP riboswitch ." Biochemistry,
49, 7351-7359. doi: 10.1021/bi100671e.
|
Crystal structure of the g20a-c92u mutant c-di-gmp
riboswith bound to c-di-amp . SNAP output
|
|
3mxh
|
RNA binding protein-RNA |
X-ray (2.3 Å) |
Smith KD, Lipchock SV, Livingston AL, Shanahan CA,
Strobel SA |
(2010) "Structural
and biochemical determinants of ligand binding by the
c-di-GMP riboswitch ." Biochemistry,
49, 7351-7359. doi: 10.1021/bi100671e.
|
Native structure of a c-di-gmp riboswitch from v.
cholerae . SNAP
output
|
|
3ncu
|
RNA binding protein-RNA |
X-ray (2.55 Å) |
Wang Y, Ludwig J, Schuberth C, Goldeck M, Schlee M,
Li H, Juranek S, Sheng G, Micura R, Tuschl T, Hartmann G,
Patel DJ |
(2010) "Structural
and functional insights into 5'-ppp RNA pattern
recognition by the innate immune receptor RIG-I."
Nat.Struct.Mol.Biol., 17,
781-787. doi: 10.1038/nsmb.1863.
|
Structural and functional insights into pattern
recognition by the innate immune receptor rig-i .
SNAP output
|
|
3ndb
|
signaling protein-RNA |
X-ray (3.0 Å) |
Hainzl T, Huang S, Merilainen G, Brannstrom K,
Sauer-Eriksson AE |
(2011) "Structural
basis of signal-sequence recognition by the signal
recognition particle."
Nat.Struct.Mol.Biol., 18,
389-391. doi: 10.1038/nsmb.1994.
|
Crystal structure of a signal sequence bound to the
signal recognition particle . SNAP output
|
|
3nl0
|
transferase-RNA |
X-ray (2.6 Å) |
Agudo R, Ferrer-Orta C, Arias A, de la Higuera I,
Perales C, Perez-Luque R, Verdaguer N, Domingo E |
(2010) "A
multi-step process of viral adaptation to a mutagenic
nucleoside analogue by modulation of transition types
leads to extinction-escape." Plos Pathog.,
6, e1001072. doi: 10.1371/journal.ppat.1001072.
|
Mutant p44s m296i of foot-and-mouth disease virus
RNA-dependent RNA polymerase . SNAP output
|
|
3nma
|
transferase-RNA |
X-ray (2.6 Å) |
Agudo R, Ferrer-Orta C, Arias A, de la Higuera I,
Perales C, Perez-Luque R, Verdaguer N, Domingo E |
(2010) "A
multi-step process of viral adaptation to a mutagenic
nucleoside analogue by modulation of transition types
leads to extinction-escape." Plos Pathog.,
6, e1001072. doi: 10.1371/journal.ppat.1001072.
|
Mutant p169s of foot-and-mouth disease virus RNA
dependent RNA-polymerase . SNAP output
|
|
3nmr
|
RNA binding protein-RNA |
X-ray (1.85 Å) |
Teplova M, Song J, Gaw HY, Teplov A, Patel DJ |
(2010) "Structural
Insights into RNA Recognition by the Alternate-Splicing
Regulator CUG-Binding Protein 1."
Structure, 18, 1364-1377.
doi: 10.1016/j.str.2010.06.018.
|
Crystal structure of cugbp1 rrm1-2-RNA complex .
SNAP output
|
|
3nmu
|
transferase-RNA |
X-ray (2.729 Å) |
Xue S, Wang R, Yang F, Terns RM, Terns MP, Zhang X,
Maxwell ES, Li H |
(2010) "Structural
basis for substrate placement by an archaeal box C/D
ribonucleoprotein particle." Mol.Cell,
39, 939-949. doi: 10.1016/j.molcel.2010.08.022.
|
Crystal structure of substrate-bound halfmer box c-d
rnp . SNAP output
|
|
3nna
|
RNA binding protein-RNA |
X-ray (1.899 Å) |
Teplova M, Song J, Gaw HY, Teplov A, Patel DJ |
(2010) "Structural
Insights into RNA Recognition by the Alternate-Splicing
Regulator CUG-Binding Protein 1."
Structure, 18, 1364-1377.
doi: 10.1016/j.str.2010.06.018.
|
Crystal structure of cugbp1 rrm1-2-RNA complex .
SNAP output
|
|
3nnc
|
RNA binding protein-RNA |
X-ray (2.2 Å) |
Teplova M, Song J, Gaw HY, Teplov A, Patel DJ |
(2010) "Structural
Insights into RNA Recognition by the Alternate-Splicing
Regulator CUG-Binding Protein 1."
Structure, 18, 1364-1377.
doi: 10.1016/j.str.2010.06.018.
|
Crystal structure of cugbp1 rrm1-2-RNA complex .
SNAP output
|
|
3nnh
|
RNA binding protein-RNA |
X-ray (2.75 Å) |
Teplova M, Song J, Gaw HY, Teplov A, Patel DJ |
(2010) "Structural
Insights into RNA Recognition by the Alternate-Splicing
Regulator CUG-Binding Protein 1."
Structure, 18, 1364-1377.
doi: 10.1016/j.str.2010.06.018.
|
Crystal structure of the cugbp1 rrm1 with guuguuuuguuu
RNA . SNAP output
|
|
3nvi
|
transferase-RNA |
X-ray (2.709 Å) |
Xue S, Wang R, Yang F, Terns RM, Terns MP, Zhang X,
Maxwell ES, Li H |
(2010) "Structural
basis for substrate placement by an archaeal box C/D
ribonucleoprotein particle." Mol.Cell,
39, 939-949. doi: 10.1016/j.molcel.2010.08.022.
|
Structure of n-terminal truncated nop56-58 bound with
l7ae and box c-d RNA . SNAP output
|
|
3nvk
|
transferase-RNA |
X-ray (3.209 Å) |
Xue S, Wang R, Yang F, Terns RM, Terns MP, Zhang X,
Maxwell ES, Li H |
(2010) "Structural
basis for substrate placement by an archaeal box C/D
ribonucleoprotein particle." Mol.Cell,
39, 939-949. doi: 10.1016/j.molcel.2010.08.022.
|
Structural basis for substrate placement by an archaeal
box c-d ribonucleoprotein particle . SNAP output
|
|
3o3i
|
RNA binding protein |
X-ray (2.801 Å) |
Tian Y, Simanshu DK, Ma JB, Patel DJ |
(2011) "Inaugural
Article: Structural basis for piRNA 2'-O-methylated
3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille)
domains." Proc.Natl.Acad.Sci.USA,
108, 903-910. doi: 10.1073/pnas.1017762108.
|
Crystal structure of human hiwi1 paz domain (residues
277-399) in complex with 14-mer RNA (12-bp + 2-nt
overhang) containing 2'-oh at its 3'-end . SNAP output
|
|
3o6e
|
RNA binding protein-RNA |
X-ray (2.904 Å) |
Tian Y, Simanshu DK, Ma JB, Patel DJ |
(2011) "Inaugural
Article: Structural basis for piRNA 2'-O-methylated
3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille)
domains." Proc.Natl.Acad.Sci.USA,
108, 903-910. doi: 10.1073/pnas.1017762108.
|
Crystal structure of human hiwi1 paz domain (residues
277-399) in complex with 14-mer RNA (12-bp + 2-nt
overhang) containing 2'-och3 at its 3'-end . SNAP output
|
|
3o7v
|
RNA binding protein-RNA |
X-ray (2.1 Å) |
Tian Y, Simanshu DK, Ma JB, Patel DJ |
(2011) "Inaugural
Article: Structural basis for piRNA 2'-O-methylated
3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille)
domains." Proc.Natl.Acad.Sci.USA,
108, 903-910. doi: 10.1073/pnas.1017762108.
|
Crystal structure of human hiwi1 (v361m) paz domain
(residues 277-399) in complex with 14-mer RNA (12-bp +
2-nt overhang) containing 2'-och3 at its 3'-end .
SNAP output
|
|
3o8c
|
hydrolase-RNA |
X-ray (2.0 Å) |
Appleby TC, Anderson R, Fedorova O, Pyle AM, Wang R,
Liu X, Brendza KM, Somoza JR |
(2011) "Visualizing
ATP-Dependent RNA Translocation by the NS3 Helicase
from HCV." J.Mol.Biol.,
405, 1139-1153. doi: 10.1016/j.jmb.2010.11.034.
|
Visualizing atp-dependent RNA translocation by the ns3
helicase from hcv . SNAP
output
|
|
3o8r
|
hydrolase-RNA |
X-ray (2.304 Å) |
Appleby TC, Anderson R, Fedorova O, Pyle AM, Wang R,
Liu X, Brendza KM, Somoza JR |
(2011) "Visualizing
ATP-Dependent RNA Translocation by the NS3 Helicase
from HCV." J.Mol.Biol.,
405, 1139-1153. doi: 10.1016/j.jmb.2010.11.034.
|
Visualizing atp-dependent RNA translocation by the ns3
helicase from hcv . SNAP
output
|
|
3og8
|
hydrolase-RNA |
X-ray (2.4 Å) |
Lu C, Ranjith-Kumar CT, Hao L, Kao CC, Li P |
(2011) "Crystal
structure of RIG-I C-terminal domain bound to
blunt-ended double-strand RNA without 5'
triphosphate." Nucleic Acids Res.,
39, 1565-1575. doi: 10.1093/nar/gkq974.
|
Crystal structure of human rig-i ctd bound to a 14-bp
blunt-ended dsrna . SNAP
output
|
|
3oij
|
ribosomal protein |
X-ray (3.0 Å) |
Thomas SR, Keller CA, Szyk A, Cannon JR,
Laronde-Leblanc NA |
(2011) "Structural
insight into the functional mechanism of Nep1/Emg1
N1-specific pseudouridine methyltransferase in ribosome
biogenesis." Nucleic Acids Res.,
39, 2445-2457. doi: 10.1093/nar/gkq1131.
|
Crystal structure of saccharomyces cerevisiae nep1-emg1
bound to s-adenosylhomocysteine and 2 molecules of
cognate RNA . SNAP
output
|
|
3oin
|
ribosomal protein |
X-ray (1.9 Å) |
Thomas SR, Keller CA, Szyk A, Cannon JR,
Laronde-Leblanc NA |
(2011) "Structural
insight into the functional mechanism of Nep1/Emg1
N1-specific pseudouridine methyltransferase in ribosome
biogenesis." Nucleic Acids Res.,
39, 2445-2457. doi: 10.1093/nar/gkq1131.
|
Crystal structure of saccharomyces cerevisiae nep1-emg1
bound to s-adenosylhomocysteine and 1 molecule of
cognate RNA . SNAP
output
|
|
3ol6
|
transferase-RNA |
X-ray (2.5 Å) |
Gong P, Peersen OB |
(2010) "Structural
basis for active site closure by the poliovirus
RNA-dependent RNA polymerase."
Proc.Natl.Acad.Sci.USA, 107,
22505-22510. doi: 10.1073/pnas.1007626107.
|
Poliovirus polymerase elongation complex . SNAP output
|
|
3ol7
|
transferase-RNA |
X-ray (2.7 Å) |
Gong P, Peersen OB |
(2010) "Structural
basis for active site closure by the poliovirus
RNA-dependent RNA polymerase."
Proc.Natl.Acad.Sci.USA, 107,
22505-22510. doi: 10.1073/pnas.1007626107.
|
Poliovirus polymerase elongation complex with ctp .
SNAP output
|
|
3ol8
|
transferase-RNA |
X-ray (2.75 Å) |
Gong P, Peersen OB |
(2010) "Structural
basis for active site closure by the poliovirus
RNA-dependent RNA polymerase."
Proc.Natl.Acad.Sci.USA, 107,
22505-22510. doi: 10.1073/pnas.1007626107.
|
Poliovirus polymerase elongation complex with ctp-mn .
SNAP output
|
|
3ol9
|
transferase-RNA |
X-ray (2.25 Å) |
Gong P, Peersen OB |
(2010) "Structural
basis for active site closure by the poliovirus
RNA-dependent RNA polymerase."
Proc.Natl.Acad.Sci.USA, 107,
22505-22510. doi: 10.1073/pnas.1007626107.
|
Poliovirus polymerase elongation complex with
3'-deoxy-ctp . SNAP
output
|
|
3ola
|
transferase-RNA |
X-ray (2.55 Å) |
Gong P, Peersen OB |
(2010) "Structural
basis for active site closure by the poliovirus
RNA-dependent RNA polymerase."
Proc.Natl.Acad.Sci.USA, 107,
22505-22510. doi: 10.1073/pnas.1007626107.
|
Poliovirus polymerase elongation complex with
2'-deoxy-ctp . SNAP
output
|
|
3olb
|
transferase-RNA |
X-ray (2.41 Å) |
Gong P, Peersen OB |
(2010) "Structural
basis for active site closure by the poliovirus
RNA-dependent RNA polymerase."
Proc.Natl.Acad.Sci.USA, 107,
22505-22510. doi: 10.1073/pnas.1007626107.
|
Poliovirus polymerase elongation complex with
2',3'-dideoxy-ctp . SNAP
output
|
|
3oto
|
ribosome |
X-ray (3.69 Å) |
Demirci H, Murphy F, Belardinelli R, Kelley AC,
Ramakrishnan V, Gregory ST, Dahlberg AE, Jogl G |
(2010) "Modification
of 16S ribosomal RNA by the KsgA methyltransferase
restructures the 30S subunit to optimize ribosome
function." Rna, 16,
2319-2324. doi: 10.1261/rna.2357210.
|
Crystal structure of the 30s ribosomal subunit from a
ksga mutant of thermus thermophilus (hb8) . SNAP output
|
|
3ouy
|
transferase-RNA |
X-ray (2.69 Å) |
Pan B, Xiong Y, Steitz TA |
(2010) "How the
CCA-Adding Enzyme Selects Adenine over Cytosine at
Position 76 of tRNA." Science,
330, 937-940. doi: 10.1126/science.1194985.
|
How the cca-adding enzyme selects adenine over cytosine
at position 76 of trna . SNAP output
|
|
3ov7
|
transferase-RNA |
X-ray (3.0 Å) |
Pan B, Xiong Y, Steitz TA |
(2010) "How the
CCA-Adding Enzyme Selects Adenine over Cytosine at
Position 76 of tRNA." Science,
330, 937-940. doi: 10.1126/science.1194985.
|
How the cca-adding enzyme selects adenine over cytosine
in position 76 of trna . SNAP output
|
|
3ova
|
transferase-RNA |
X-ray (1.98 Å) |
Pan B, Xiong Y, Steitz TA |
(2010) "How the
CCA-Adding Enzyme Selects Adenine over Cytosine at
Position 76 of tRNA." Science,
330, 937-940. doi: 10.1126/science.1194985.
|
How the cca-adding enzyme selects adenine over cytosine
in position 76 of trna . SNAP output
|
|
3ovb
|
transferase-RNA |
X-ray (1.95 Å) |
Pan B, Xiong Y, Steitz TA |
(2010) "How the
CCA-Adding Enzyme Selects Adenine over Cytosine at
Position 76 of tRNA." Science,
330, 937-940. doi: 10.1126/science.1194985.
|
How the cca-adding enzyme selects adenine over cytosine
in position 76 of trna . SNAP output
|
|
3ovs
|
transferase-RNA |
X-ray (2.8 Å) |
Pan B, Xiong Y, Steitz TA |
(2010) "How the
CCA-Adding Enzyme Selects Adenine over Cytosine at
Position 76 of tRNA." Science,
330, 937-940. doi: 10.1126/science.1194985.
|
How the cca-adding enzyme selects adenine over cytosine
in position 76 of trna . SNAP output
|
|
3ow2
|
ribosome |
X-ray (2.7 Å) |
|
|
Crystal structure of enhanced macrolide bound to 50s
ribosomal subunit . SNAP
output
|
|
3p49
|
RNA binding protein-RNA |
X-ray (3.55 Å) |
Butler EB, Xiong Y, Wang J, Strobel SA |
(2011) "Structural
basis of cooperative ligand binding by the glycine
riboswitch." Chem.Biol.,
18, 293-298. doi: 10.1016/j.chembiol.2011.01.013.
|
Crystal structure of a glycine riboswitch from
fusobacterium nucleatum . SNAP output
|
|
3pdm
|
virus |
fiber diffraction |
Tewary SK, Oda T, Kendall A, Bian W, Stubbs G, Wong
SM, Swaminathan K |
(2010) "Structure
of Hibiscus latent Singapore virus by fiber
diffraction: A non-conserved His122 contributes to coat
protein stability." J.Mol.Biol. doi:
10.1016/j.jmb.2010.12.032.
|
Hibiscus latent singapore virus . SNAP output
|
|
3pew
|
hydrolase-RNA |
X-ray (1.501 Å) |
Montpetit B, Thomsen ND, Helmke KJ, Seeliger MA,
Berger JM, Weis K |
(2011) "A
conserved mechanism of DEAD-box ATPase activation by
nucleoporins and InsP(6) in mRNA export."
Nature, 472, 238-242. doi:
10.1038/nature09862.
|
S. cerevisiae dbp5 l327v bound to RNA and adp bef3 .
SNAP output
|
|
3pey
|
hydrolase-RNA |
X-ray (1.401 Å) |
Montpetit B, Thomsen ND, Helmke KJ, Seeliger MA,
Berger JM, Weis K |
(2011) "A
conserved mechanism of DEAD-box ATPase activation by
nucleoporins and InsP(6) in mRNA export."
Nature, 472, 238-242. doi:
10.1038/nature09862.
|
S. cerevisiae dbp5 bound to RNA and adp bef3 . SNAP output
|
|
3pf4
|
gene regulation-RNA |
X-ray (1.38 Å) |
Sachs R, Max KE, Heinemann U, Balbach J |
(2012) "RNA
single strands bind to a conserved surface of the major
cold shock protein in crystals and solution."
Rna, 18, 65-76. doi: 10.1261/rna.02809212.
|
Crystal structure of bs-cspb in complex with r(gucuuua)
. SNAP output
|
|
3pf5
|
gene regulation-RNA |
X-ray (1.68 Å) |
Sachs R, Max KE, Heinemann U, Balbach J |
(2012) "RNA
single strands bind to a conserved surface of the major
cold shock protein in crystals and solution."
Rna, 18, 65-76. doi: 10.1261/rna.02809212.
|
Crystal structure of bs-cspb in complex with ru6 .
SNAP output
|
|
3pio
|
ribosome-antibiotic |
X-ray (3.25 Å) |
Belousoff MJ, Shapira T, Bashan A, Zimmerman E,
Rozenberg H, Arakawa K, Kinashi H, Yonath A |
(2011) "Crystal
structure of the synergistic antibiotic pair,
lankamycin and lankacidin, in complex with the large
ribosomal subunit."
Proc.Natl.Acad.Sci.USA, 108,
2717-2722. doi: 10.1073/pnas.1019406108.
|
Crystal structure of the synergistic antibiotic pair
lankamycin and lankacidin in complex with the large
ribosomal subunit . SNAP
output
|
|
3pip
|
ribosome-antibiotic |
X-ray (3.45 Å) |
Belousoff MJ, Shapira T, Bashan A, Zimmerman E,
Rozenberg H, Arakawa K, Kinashi H, Yonath A |
(2011) "Crystal
structure of the synergistic antibiotic pair,
lankamycin and lankacidin, in complex with the large
ribosomal subunit."
Proc.Natl.Acad.Sci.USA, 108,
2717-2722. doi: 10.1073/pnas.1019406108.
|
Crystal structure of the synergistic antibiotic pair
lankamycin and lankacidin in complex with the large
ribosomal subunit . SNAP
output
|
|
3pkm
|
hydrolase-RNA |
X-ray (3.103 Å) |
Wang R, Preamplume G, Terns MP, Terns RM, Li H |
(2011) "Interaction
of the Cas6 Riboendonuclease with CRISPR RNAs:
Recognition and Cleavage." Structure,
19, 257-264. doi: 10.1016/j.str.2010.11.014.
|
Crystal structure of cas6 with its substrate RNA .
SNAP output
|
|
3pla
|
transferase-RNA |
X-ray (3.15 Å) |
Lin J, Lai S, Jia R, Xu A, Zhang L, Lu J, Ye K |
(2011) "Structural
basis for site-specific ribose methylation by box C/D
RNA protein complexes." Nature,
469, 559-563. doi: 10.1038/nature09688.
|
Crystal structure of a catalytically active
substrate-bound box c-d rnp from sulfolobus
solfataricus . SNAP
output
|
|
3ptx
|
viral protein-RNA |
X-ray (3.0 Å) |
Green TJ, Rowse M, Tsao J, Kang J, Ge P, Zhou ZH, Luo
M |
(2011) "Access
to RNA Encapsidated in the Nucleocapsid of Vesicular
Stomatitis Virus." J.Virol.,
85, 2714-2722. doi: 10.1128/JVI.01927-10.
|
Crystal structure of a vesicular stomatitis virus
nucleocapsid-polya complex . SNAP output
|
|
3pu0
|
viral protein-RNA |
X-ray (3.09 Å) |
Green TJ, Rowse M, Tsao J, Kang J, Ge P, Zhou ZH, Luo
M |
(2011) "Access
to RNA Encapsidated in the Nucleocapsid of Vesicular
Stomatitis Virus." J.Virol.,
85, 2714-2722. doi: 10.1128/JVI.01927-10.
|
Crystal structure of a vesicular stomatitis virus
nucleocapsid-polyc complex . SNAP output
|
|
3pu1
|
viral protein-RNA |
X-ray (3.14 Å) |
Green TJ, Rowse M, Tsao J, Kang J, Ge P, Zhou ZH, Luo
M |
(2011) "Access
to RNA Encapsidated in the Nucleocapsid of Vesicular
Stomatitis Virus." J.Virol.,
85, 2714-2722. doi: 10.1128/JVI.01927-10.
|
Crystal structure of a vesicular stomatitis virus
nucleocapsid-polyg complex . SNAP output
|
|
3pu4
|
viral protein-RNA |
X-ray (3.0 Å) |
Green TJ, Rowse M, Tsao J, Kang J, Ge P, Zhou ZH, Luo
M |
(2011) "Access
to RNA Encapsidated in the Nucleocapsid of Vesicular
Stomatitis Virus." J.Virol.,
85, 2714-2722. doi: 10.1128/JVI.01927-10.
|
Crystal structure of a vesicular stomatitis virus
nucleocapsid-polyu complex . SNAP output
|
|
3q0l
|
RNA binding protein-RNA |
X-ray (2.503 Å) |
Lu G, Hall TM |
(2011) "Alternate
modes of cognate RNA recognition by human PUMILIO
proteins." Structure, 19,
361-367. doi: 10.1016/j.str.2010.12.019.
|
Crystal structure of the pumilio-homology domain from
human pumilio1 in complex with p38alpha nrea . SNAP output
|
|
3q0m
|
RNA binding protein-RNA |
X-ray (2.705 Å) |
Lu G, Hall TM |
(2011) "Alternate
modes of cognate RNA recognition by human PUMILIO
proteins." Structure, 19,
361-367. doi: 10.1016/j.str.2010.12.019.
|
Crystal structure of the pumilio-homology domain from
human pumilio1 in complex with p38alpha nreb . SNAP output
|
|
3q0n
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Lu G, Hall TM |
(2011) "Alternate
modes of cognate RNA recognition by human PUMILIO
proteins." Structure, 19,
361-367. doi: 10.1016/j.str.2010.12.019.
|
Crystal structure of the pumilio-homology domain from
human pumilio1 in complex with erk2 nre . SNAP output
|
|
3q0o
|
RNA binding protein-RNA |
X-ray (2.804 Å) |
Lu G, Hall TM |
(2011) "Alternate
modes of cognate RNA recognition by human PUMILIO
proteins." Structure, 19,
361-367. doi: 10.1016/j.str.2010.12.019.
|
Crystal structure of the pumilio-homology domain from
human pumilio1 in complex with erk2 nre . SNAP output
|
|
3q0p
|
RNA binding protein-RNA |
X-ray (2.6 Å) |
Lu G, Hall TM |
(2011) "Alternate
modes of cognate RNA recognition by human PUMILIO
proteins." Structure, 19,
361-367. doi: 10.1016/j.str.2010.12.019.
|
Crystal structure of the pumilio-homology domain from
human pumilio1 in complex with hunchback nre . SNAP output
|
|
3q0q
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Lu G, Hall TM |
(2011) "Alternate
modes of cognate RNA recognition by human PUMILIO
proteins." Structure, 19,
361-367. doi: 10.1016/j.str.2010.12.019.
|
Crystal structure of the pumilio-homology domain from
human pumilio2 in complex with p38alpha nrea . SNAP output
|
|
3q0r
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Lu G, Hall TM |
(2011) "Alternate
modes of cognate RNA recognition by human PUMILIO
proteins." Structure, 19,
361-367. doi: 10.1016/j.str.2010.12.019.
|
Crystal structure of the pumilio-homology domain from
human pumilio2 in complex with p38alpha nreb . SNAP output
|
|
3q0s
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Lu G, Hall TM |
(2011) "Alternate
modes of cognate RNA recognition by human PUMILIO
proteins." Structure, 19,
361-367. doi: 10.1016/j.str.2010.12.019.
|
Crystal structure of the pumilio-homology domain from
human pumilio2 in complex with erk2 nre . SNAP output
|
|
3q2t
|
RNA binding protein-RNA |
X-ray (3.061 Å) |
Yang Q, Coseno M, Gilmartin GM, Doublie S |
(2011) "Crystal
Structure of a Human Cleavage Factor
CFI(m)25/CFI(m)68/RNA Complex Provides an Insight into
Poly(A) Site Recognition and RNA Looping."
Structure, 19, 368-377. doi:
10.1016/j.str.2010.12.021.
|
Crystal structure of cfim68 rrm-cfim25-RNA complex .
SNAP output
|
|
3qg9
|
RNA binding protein-RNA |
X-ray (2.25 Å) |
Koh YY, Wang Y, Qiu C, Opperman L, Gross L, Tanaka
Hall TM, Wickens M |
(2011) "Stacking
interactions in PUF-RNA complexes." Rna,
17, 718-727. doi: 10.1261/rna.2540311.
|
Crystal structure of fbf-2-gld-1 fbea a7u mutant
complex . SNAP
output
|
|
3qgb
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Koh YY, Wang Y, Qiu C, Opperman L, Gross L, Tanaka
Hall TM, Wickens M |
(2011) "Stacking
interactions in PUF-RNA complexes." Rna,
17, 718-727. doi: 10.1261/rna.2540311.
|
Crystal structure of fbf-2 r288y mutant in complex with
gld-1 fbea . SNAP
output
|
|
3qgc
|
RNA binding protein-RNA |
X-ray (1.9 Å) |
Koh YY, Wang Y, Qiu C, Opperman L, Gross L, Tanaka
Hall TM, Wickens M |
(2011) "Stacking
interactions in PUF-RNA complexes." Rna,
17, 718-727. doi: 10.1261/rna.2540311.
|
Crystal structure of fbf-2 r288y mutant in complex with
gld-1 fbea a7u mutant . SNAP output
|
|
3qjj
|
immune system-RNA |
X-ray (2.8 Å) |
Wang R, Zheng H, Preamplume G, Li H |
"Cooperative and Specific Binding of a RAMP Protein
to Single-stranded CRISPR Repeat RNA." |
One ramp protein binding different RNA substrates .
SNAP output
|
|
3qjl
|
immune system-RNA |
X-ray (2.7 Å) |
Wang R, Zheng H, Preamplume G, Li H |
"Cooperative and Specific Binding of a RAMP Protein
to Single-stranded CRISPR Repeat RNA." |
One ramp protein binding different RNA substrates .
SNAP output
|
|
3qjp
|
immune system-RNA |
X-ray (3.3 Å) |
Wang R, Zheng H, Preamplume G, Li H |
"Cooperative and Specific Binding of a RAMP Protein
to Single-stranded CRISPR Repeat RNA." |
An ramp protein binding different RNA substrates .
SNAP output
|
|
3qrp
|
RNA binding protein-RNA |
X-ray (2.352 Å) |
Gesner EM, Schellenberg MJ, Garside EL, George MM,
Macmillan AM |
(2011) "Recognition
and maturation of effector RNAs in a CRISPR
interference pathway."
Nat.Struct.Mol.Biol., 18,
688-692. doi: 10.1038/nsmb.2042.
|
Structure of thermus thermophilus cse3 bound to an RNA
representing a product mimic complex . SNAP output
|
|
3qrq
|
RNA binding protein-RNA |
X-ray (3.194 Å) |
Gesner EM, Schellenberg MJ, Garside EL, George MM,
Macmillan AM |
(2011) "Recognition
and maturation of effector RNAs in a CRISPR
interference pathway."
Nat.Struct.Mol.Biol., 18,
688-692. doi: 10.1038/nsmb.2042.
|
Structure of thermus thermophilus cse3 bound to an RNA
representing a pre-cleavage complex . SNAP output
|
|
3qrr
|
RNA binding protein-RNA |
X-ray (3.099 Å) |
Gesner EM, Schellenberg MJ, Garside EL, George MM,
Macmillan AM |
(2011) "Recognition
and maturation of effector RNAs in a CRISPR
interference pathway."
Nat.Struct.Mol.Biol., 18,
688-692. doi: 10.1038/nsmb.2042.
|
Structure of thermus thermophilus cse3 bound to an RNA
representing a product complex . SNAP output
|
|
3qsu
|
chaperone-RNA |
X-ray (2.2 Å) |
Horstmann N, Orans J, Valentin-Hansen P, Shelburne
SA, Brennan RG |
(2012) "Structural
mechanism of Staphylococcus aureus Hfq binding to an
RNA A-tract." Nucleic Acids Res.,
40, 11023-11035. doi: 10.1093/nar/gks809.
|
Structure of staphylococcus aureus hfq in complex with
a7 RNA . SNAP output
|
|
3qsy
|
translation-RNA |
X-ray (3.2 Å) |
Stolboushkina E, Nikonov S, Zelinskaya N, Arkhipova
V, Nikulin A, Garber M, Nikonov O |
(2013) "Crystal
structure of the archaeal translation initiation factor
2 in complex with a GTP analogue and
Met-tRNAf(Met.)." J.Mol.Biol.,
425, 989-998. doi: 10.1016/j.jmb.2012.12.023.
|
Recognition of the methionylated initiator trna by the
translation initiation factor 2 in archaea . SNAP output
|
|
3r1h
|
RNA binding protein-RNA |
X-ray (3.15 Å) |
Shechner DM, Bartel DP |
(2011) "The
structural basis of RNA-catalyzed RNA
polymerization." Nat.Struct.Mol.Biol.,
18, 1036-1042. doi: 10.1038/nsmb.2107.
|
Crystal structure of the class i ligase
ribozyme-substrate preligation complex, c47u mutant,
ca2+ bound . SNAP
output
|
|
3r1l
|
RNA binding protein-RNA |
X-ray (3.125 Å) |
Shechner DM, Bartel DP |
(2011) "The
structural basis of RNA-catalyzed RNA
polymerization." Nat.Struct.Mol.Biol.,
18, 1036-1042. doi: 10.1038/nsmb.2107.
|
Crystal structure of the class i ligase
ribozyme-substrate preligation complex, c47u mutant,
mg2+ bound . SNAP
output
|
|
3r2c
|
transcription-RNA |
X-ray (1.902 Å) |
Stagno JR, Altieri AS, Bubunenko M, Tarasov SG, Li J,
Court DL, Byrd RA, Ji X |
(2011) "Structural
basis for RNA recognition by NusB and NusE in the
initiation of transcription antitermination."
Nucleic Acids Res., 39,
7803-7815. doi: 10.1093/nar/gkr418.
|
Crystal structure of antitermination factors nusb and
nuse in complex with boxa RNA . SNAP output
|
|
3r2d
|
transcription-RNA |
X-ray (2.199 Å) |
Stagno JR, Altieri AS, Bubunenko M, Tarasov SG, Li J,
Court DL, Byrd RA, Ji X |
(2011) "Structural
basis for RNA recognition by NusB and NusE in the
initiation of transcription antitermination."
Nucleic Acids Res., 39,
7803-7815. doi: 10.1093/nar/gkr418.
|
Crystal structure of antitermination factors nusb and
nuse in complex with dsrna . SNAP output
|
|
3r9w
|
hydrolase-RNA |
X-ray (2.05 Å) |
Tu C, Zhou X, Tarasov SG, Tropea JE, Austin BP, Waugh
DS, Court DL, Ji X |
(2011) "The Era
GTPase recognizes the GAUCACCUCC sequence and binds
helix 45 near the 3' end of 16S rRNA."
Proc.Natl.Acad.Sci.USA, 108,
10156-10161. doi: 10.1073/pnas.1017679108.
|
Crystal structure of era in complex with mggdpnp and
nucleotides 1506-1542 of 16s ribosomal RNA . SNAP output
|
|
3r9x
|
hydrolase-transferase-RNA |
X-ray (2.8 Å) |
Tu C, Zhou X, Tarasov SG, Tropea JE, Austin BP, Waugh
DS, Court DL, Ji X |
(2011) "The Era
GTPase recognizes the GAUCACCUCC sequence and binds
helix 45 near the 3' end of 16S rRNA."
Proc.Natl.Acad.Sci.USA, 108,
10156-10161. doi: 10.1073/pnas.1017679108.
|
Crystal structure of era in complex with mggdpnp,
nucleotides 1506-1542 of 16s ribosomal RNA, and ksga .
SNAP output
|
|
3rc8
|
hydrolase-RNA |
X-ray (2.9 Å) |
Jedrzejczak R, Wang J, Dauter M, Szczesny RJ, Stepien
PP, Dauter Z |
(2011) "Human
Suv3 protein reveals unique features among SF2
helicases." Acta Crystallogr.,Sect.D,
67, 988-996. doi: 10.1107/S0907444911040248.
|
Human mitochondrial helicase suv3 in complex with short
RNA fragment . SNAP
output
|
|
3rer
|
chaperone-RNA |
X-ray (1.7 Å) |
Wang W, Wang L, Zou Y, Zhang J, Gong Q, Wu J, Shi
Y |
(2011) "Cooperation
of Escherichia coli Hfq hexamers in DsrA binding."
Genes Dev., 25, 2106-2117.
doi: 10.1101/gad.16746011.
|
Crystal structure of e. coli hfq in complex with au6a
RNA and adp . SNAP
output
|
|
3rtj
|
hydrolase-RNA |
X-ray (3.0 Å) |
Monzingo AF, Robertus JD |
(1992) "X-ray
analysis of substrate analogs in the ricin A-chain
active site." J.Mol.Biol.,
227, 1136-1145.
|
Crystal structure of ricin bound with dinucleotide apg
. SNAP output
|
|
3rw6
|
transport protein-RNA |
X-ray (2.3 Å) |
Teplova M, Wohlbold L, Khin NW, Izaurralde E, Patel
DJ |
(2011) "Structure-function
studies of nucleocytoplasmic transport of retroviral
genomic RNA by mRNA export factor TAP."
Nat.Struct.Mol.Biol., 18,
990-998. doi: 10.1038/nsmb.2094.
|
Structure of nuclear RNA export factor tap bound to cte
RNA . SNAP output
|
|
3s4g
|
virus |
X-ray (6.0 Å) |
Lane SW, Dennis CA, Lane CL, Trinh CH, Rizkallah PJ,
Stockley PG, Phillips SE |
(2011) "Construction
and crystal structure of recombinant STNV capsids."
J.Mol.Biol., 413, 41-50. doi:
10.1016/j.jmb.2011.07.062.
|
Low resolution structure of stnv complexed with RNA .
SNAP output
|
|
3siu
|
splicing-RNA |
X-ray (2.626 Å) |
Liu S, Ghalei H, Luhrmann R, Wahl MC |
(2011) "Structural
basis for the dual U4 and U4atac snRNA-binding
specificity of spliceosomal protein hPrp31."
Rna, 17, 1655-1663. doi:
10.1261/rna.2690611.
|
Structure of a hprp31-15.5k-u4atac 5' stem loop
complex, monomeric form . SNAP output
|
|
3siv
|
splicing-RNA |
X-ray (3.304 Å) |
Liu S, Ghalei H, Luhrmann R, Wahl MC |
(2011) "Structural
basis for the dual U4 and U4atac snRNA-binding
specificity of spliceosomal protein hPrp31."
Rna, 17, 1655-1663. doi:
10.1261/rna.2690611.
|
Structure of a hprp31-15.5k-u4atac 5' stem loop
complex, dimeric form . SNAP output
|
|
3sn2
|
lyase-RNA |
X-ray (2.99 Å) |
Walden WE, Selezneva A, Volz K |
(2012) "Accommodating
variety in iron-responsive elements: Crystal structure
of transferrin receptor 1 B IRE bound to iron
regulatory protein 1." Febs Lett.,
586, 32-35. doi: 10.1016/j.febslet.2011.11.018.
|
Crystal structure analysis of iron regulatory protein 1
in complex with transferrin receptor ire b RNA .
SNAP output
|
|
3snp
|
lyase-RNA |
X-ray (2.8 Å) |
Walden WE, Selezneva AI, Dupuy J, Volbeda A,
Fontecilla-Camps JC, Theil EC, Volz K |
(2006) "Structure
of dual function iron regulatory protein 1 complexed
with ferritin IRE-RNA." Science,
314, 1903-1908. doi: 10.1126/science.1133116.
|
Crystal structure analysis of iron regulatory protein 1
in complex with ferritin h ire RNA . SNAP output
|
|
3sqw
|
hydrolase-RNA |
X-ray (1.909 Å) |
Mohr G, Del Campo M, Turner KG, Gilman B, Wolf RZ,
Lambowitz AM |
(2011) "High-Throughput
Genetic Identification of Functionally Important
Regions of the Yeast DEAD-Box Protein Mss116p."
J.Mol.Biol., 413, 952-972.
doi: 10.1016/j.jmb.2011.09.015.
|
Structure of mss116p (nte deletion) bound to ssrna and
amp-pnp . SNAP
output
|
|
3t1h
|
ribosome-antibiotic |
X-ray (3.11 Å) |
Vendeix FA, Murphy FV, Cantara WA, Leszczynska G,
Gustilo EM, Sproat B, Malkiewicz A, Agris PF |
(2012) "Human
tRNA(Lys3)(UUU) Is Pre-Structured by Natural
Modifications for Cognate and Wobble Codon Binding
through Keto-Enol Tautomerism."
J.Mol.Biol., 416, 467-485.
doi: 10.1016/j.jmb.2011.12.048.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a human anti-codon stem loop
(hasl) of transfer RNA lysine 3 (trnalys3) bound to an
mrna with an aaa-codon in the a-site and paromomycin .
SNAP output
|
|
3t1y
|
ribosome-antibiotic |
X-ray (2.8 Å) |
Vendeix FA, Murphy FV, Cantara WA, Leszczynska G,
Gustilo EM, Sproat B, Malkiewicz A, Agris PF |
(2012) "Human
tRNA(Lys3)(UUU) Is Pre-Structured by Natural
Modifications for Cognate and Wobble Codon Binding
through Keto-Enol Tautomerism."
J.Mol.Biol., 416, 467-485.
doi: 10.1016/j.jmb.2011.12.048.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a human anti-codon stem loop
(hasl) of transfer RNA lysine 3 (trnalys3) bound to an
mrna with an aag-codon in the a-site and paromomycin .
SNAP output
|
|
3t3n
|
hydrolase-RNA |
X-ray (3.09 Å) |
Dorleans A, Li de la Sierra-Gallay I, Piton J, Zig L,
Gilet L, Putzer H, Condon C |
(2011) "Molecular
Basis for the Recognition and Cleavage of RNA by the
Bifunctional 5'-3' Exo/Endoribonuclease RNase J."
Structure, 19, 1252-1261.
doi: 10.1016/j.str.2011.06.018.
|
Molecular basis for the recognition and cleavage of RNA
(uuccgu) by the bifunctional 5'-3' exo-endoribonuclease
rnase j . SNAP
output
|
|
3t3o
|
hydrolase-RNA |
X-ray (2.5 Å) |
Dorleans A, Li de la Sierra-Gallay I, Piton J, Zig L,
Gilet L, Putzer H, Condon C |
(2011) "Molecular
Basis for the Recognition and Cleavage of RNA by the
Bifunctional 5'-3' Exo/Endoribonuclease RNase J."
Structure, 19, 1252-1261.
doi: 10.1016/j.str.2011.06.018.
|
Molecular basis for the recognition and cleavage of RNA
(cugg) by the bifunctional 5'-3' exo-endoribonuclease
rnase j . SNAP
output
|
|
3t5n
|
viral protein-RNA |
X-ray (1.787 Å) |
Hastie KM, Liu T, Li S, King LB, Ngo N, Zandonatti
MA, Woods VL, de la Torre JC, Saphire EO |
(2011) "Crystal
structure of the Lassa virus nucleoprotein-RNA complex
reveals a gating mechanism for RNA binding."
Proc.Natl.Acad.Sci.USA, 108,
19365-19370. doi: 10.1073/pnas.1108515108.
|
1.8a crystal structure of lassa virus nucleoprotein in
complex with ssrna . SNAP output
|
|
3t5q
|
viral protein-RNA |
X-ray (3.0 Å) |
Hastie KM, Liu T, Li S, King LB, Ngo N, Zandonatti
MA, Woods VL, de la Torre JC, Saphire EO |
(2011) "Crystal
structure of the Lassa virus nucleoprotein-RNA complex
reveals a gating mechanism for RNA binding."
Proc.Natl.Acad.Sci.USA, 108,
19365-19370. doi: 10.1073/pnas.1108515108.
|
3a structure of lassa virus nucleoprotein in complex
with ssrna . SNAP
output
|
|
3trz
|
RNA binding protein-RNA |
X-ray (2.9 Å) |
Nam Y, Chen C, Gregory RI, Chou JJ, Sliz P |
(2011) "Molecular
Basis for Interaction of let-7 MicroRNAs with
Lin28." Cell(Cambridge,Mass.),
147, 1080-1091. doi: 10.1016/j.cell.2011.10.020.
|
Mouse lin28a in complex with let-7d microrna
pre-element . SNAP
output
|
|
3ts0
|
RNA binding protein-RNA |
X-ray (2.763 Å) |
Nam Y, Chen C, Gregory RI, Chou JJ, Sliz P |
(2011) "Molecular
Basis for Interaction of let-7 MicroRNAs with
Lin28." Cell(Cambridge,Mass.),
147, 1080-1091. doi: 10.1016/j.cell.2011.10.020.
|
Mouse lin28a in complex with let-7f-1 microrna
pre-element . SNAP
output
|
|
3ts2
|
RNA binding protein-RNA |
X-ray (2.01 Å) |
Nam Y, Chen C, Gregory RI, Chou JJ, Sliz P |
(2011) "Molecular
Basis for Interaction of let-7 MicroRNAs with
Lin28." Cell(Cambridge,Mass.),
147, 1080-1091. doi: 10.1016/j.cell.2011.10.020.
|
Mouse lin28a in complex with let-7g microrna
pre-element . SNAP
output
|
|
3tup
|
ligase-RNA |
X-ray (3.05 Å) |
Klipcan L, Moor N, Finarov I, Kessler N, Sukhanova M,
Safro MG |
(2012) "Crystal
Structure of Human Mitochondrial PheRS Complexed with
tRNA(Phe) in the Active "Open" State."
J.Mol.Biol., 415, 527-537.
doi: 10.1016/j.jmb.2011.11.029.
|
Crystal structure of human mitochondrial phers
complexed with trnaphe in the active open state .
SNAP output
|
|
3u2e
|
lyase-RNA |
X-ray (2.32 Å) |
Filippova EV, Minasov G, Shuvalova L, Kiryukhina O,
Massa C, Schirmer T, Joachimiak A, Anderson WF, Midwest
Center for Structural Genomics (MCSG) |
"EAL domain from Caulobacter crescentus in complex
with 5'-pGpG and Mg++." |
Eal domain of phosphodiesterase pdea in complex with
5'-pgpg and mg++ . SNAP
output
|
|
3u4m
|
RNA-RNA binding protein |
X-ray (2.0 Å) |
Tishchenko S, Gabdulkhakov A, Nevskaya N, Sarskikh A,
Kostareva O, Nikonova E, Sycheva A, Moshkovskii S, Garber
M, Nikonov S |
(2012) "High-resolution
crystal structure of the isolated ribosomal L1
stalk." Acta Crystallogr.,Sect.D,
68, 1051-1057. doi: 10.1107/S0907444912020136.
|
Crystal structure of ribosomal protein tthl1 in complex
with 80nt 23s RNA from thermus thermophilus . SNAP output
|
|
3u56
|
RNA-RNA binding protein |
X-ray (2.1 Å) |
Tishchenko SV, Nikonova EY, Kostareva OS,
Gabdulkhakov AG, Sarskikh AV, Piendl W, Nikonov SV,
Garber MB, Nevskaya NA |
"Crystal structure of ribosomal protein tthl1 in
complex with 80nt 23s rna from thermus
thermophilus." |
Crystal structure of mutant ribosomal protein t217v
tthl1 in complex with 80nt 23s RNA from thermus
thermophilus . SNAP
output
|
|
3ucu
|
signaling protein-RNA |
X-ray (2.8 Å) |
Smith KD, Lipchock SV, Strobel SA |
(2012) "Structural
and biochemical characterization of linear dinucleotide
analogues bound to the c-di-GMP-I aptamer."
Biochemistry, 51, 425-432.
doi: 10.1021/bi2016662.
|
The c-di-gmp-i riboswitch bound to pgpg . SNAP output
|
|
3ucz
|
signaling protein-RNA |
X-ray (2.8 Å) |
Smith KD, Lipchock SV, Strobel SA |
(2012) "Structural
and biochemical characterization of linear dinucleotide
analogues bound to the c-di-GMP-I aptamer."
Biochemistry, 51, 425-432.
doi: 10.1021/bi2016662.
|
The c-di-gmp-i riboswitch bound to gpg . SNAP output
|
|
3ud3
|
signaling protein-RNA |
X-ray (3.1 Å) |
Smith KD, Lipchock SV, Strobel SA |
(2012) "Structural
and biochemical characterization of linear dinucleotide
analogues bound to the c-di-GMP-I aptamer."
Biochemistry, 51, 425-432.
doi: 10.1021/bi2016662.
|
The c92u mutant c-di-gmp-i riboswitch bound to pgpa .
SNAP output
|
|
3ud4
|
signaling protein-RNA |
X-ray (2.7 Å) |
Smith KD, Lipchock SV, Strobel SA |
(2012) "Structural
and biochemical characterization of linear dinucleotide
analogues bound to the c-di-GMP-I aptamer."
Biochemistry, 51, 425-432.
doi: 10.1021/bi2016662.
|
The c92u mutant c-di-gmp-i riboswitch bound to gpa .
SNAP output
|
|
3umy
|
rrna binding protein-RNA |
X-ray (1.9 Å) |
Tishchenko SV, Nikonova EY, Kostareva OS,
Gabdulkhakov AG, Sarskikh AV, Piendl W, Nikonov SV,
Garber MB, Nevskaya NA |
"Crystal structure of mutant ribosomal protein T217A
TthL1 in complex with 80nt 23S RNA from Thermus
thermophilus." |
Crystal structure of mutant ribosomal protein t217a
tthl1 in complex with 80nt 23s RNA from thermus
thermophilus . SNAP
output
|
|
3uzs
|
transferase-RNA |
X-ray (4.52 Å) |
Tesmer VM, Lennarz S, Mayer G, Tesmer JJ |
(2012) "Molecular
mechanism for inhibition of g protein-coupled receptor
kinase 2 by a selective RNA aptamer."
Structure, 20, 1300-1309.
doi: 10.1016/j.str.2012.05.002.
|
Structure of the c13.28 RNA aptamer bound to the g
protein-coupled receptor kinase 2-heterotrimeric g
protein beta 1 and gamma 2 subunit complex . SNAP output
|
|
3uzt
|
transferase-RNA |
X-ray (3.51 Å) |
Tesmer VM, Lennarz S, Mayer G, Tesmer JJ |
(2012) "Molecular
mechanism for inhibition of g protein-coupled receptor
kinase 2 by a selective RNA aptamer."
Structure, 20, 1300-1309.
doi: 10.1016/j.str.2012.05.002.
|
Structure of the c13.18 RNA aptamer in complex with g
protein-coupled receptor kinase 2 . SNAP output
|
|
3v11
|
translation-RNA |
X-ray (5.0 Å) |
Schmitt E, Panvert M, Lazennec-Schurdevin C, Coureux
PD, Perez J, Thompson A, Mechulam Y |
(2012) "Structure
of the ternary initiation complex
aIF2-GDPNP-methionylated initiator tRNA."
Nat.Struct.Mol.Biol., 19,
450-454. doi: 10.1038/nsmb.2259.
|
Structure of the ternary initiation complex
aif2:gdpnp:methionylated initiator trna . SNAP output
|
|
3v6y
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Qiu C, Kershner A, Wang Y, Holley CH, Wilinski D,
Keles S, Kimble J, Wickens M, Hall TMT |
(2012) "Divergence of PUF protein specificity through
variations in an RNA-binding pocket."
J.Biol.Chem. |
Crystal structure of fbf-2 in complex with a mutant
gld-1 fbea13 RNA . SNAP
output
|
|
3v71
|
RNA binding protein-RNA |
X-ray (2.902 Å) |
Qiu C, Kershner A, Wang Y, Holley CH, Wilinski D,
Keles S, Kimble J, Wickens M, Hall TMT |
(2012) "Divergence of PUF protein specificity through
variations in an RNA-binding pocket."
J.Biol.Chem. |
Crystal structure of puf-6 in complex with 5be13 RNA .
SNAP output
|
|
3v74
|
RNA binding protein-RNA |
X-ray (2.3 Å) |
Wang Y, Qiu C, Kershner A, Holley CP, Wilinski D,
Keles S, Kimble J, Wickens M, Hall TMT |
(2012) "Divergence of PUF protein specificity through
variations in an RNA-binding pocket."
J.Biol.Chem. |
Crystal structure of fbf-2 in complex with gld-1 fbea13
RNA . SNAP output
|
|
3v7e
|
ribosomal protein-RNA |
X-ray (2.8 Å) |
Baird NJ, Zhang J, Hamma T, Ferre-D'Amare AR |
(2012) "YbxF and
YlxQ are bacterial homologs of L7Ae and bind K-turns
but not K-loops." Rna,
18, 759-770. doi: 10.1261/rna.031518.111.
|
Crystal structure of ybxf bound to the sam-i riboswitch
aptamer . SNAP
output
|
|
3vjr
|
hydrolase-RNA |
X-ray (2.4 Å) |
Ito K, Murakami R, Mochizuki M, Qi H, Shimizu Y,
Miura K, Ueda T, Uchiumi T |
(2012) "Structural
basis for the substrate recognition and catalysis of
peptidyl-tRNA hydrolase." Nucleic Acids
Res., 40, 10521-10531. doi:
10.1093/nar/gks790.
|
Crystal structure of peptidyl-trna hydrolase from
escherichia coli in complex with the
cca-acceptor-t[psi]c domain of trna . SNAP output
|
|
3vnu
|
translation, transferase-RNA |
X-ray (3.2 Å) |
Takeshita D, Yamashita S, Tomita K |
(2012) "Mechanism
for template-independent terminal adenylation activity
of Q beta replicase." Structure,
20, 1661-1669. doi: 10.1016/j.str.2012.07.004.
|
Complex structure of viral RNA polymerase i . SNAP output
|
|
3vnv
|
translation, transferase-RNA |
X-ray (2.604 Å) |
Takeshita D, Yamashita S, Tomita K |
(2012) "Mechanism
for template-independent terminal adenylation activity
of Q beta replicase." Structure,
20, 1661-1669. doi: 10.1016/j.str.2012.07.004.
|
Complex structure of viral RNA polymerase ii . SNAP output
|
|
3vyx
|
hydrolase-RNA |
X-ray (2.29 Å) |
Fu Q, Yuan YA |
(2013) "Structural
insights into RISC assembly facilitated by
dsRNA-binding domains of human RNA helicase A
(DHX9)." Nucleic Acids Res.,
41, 3457-3470. doi: 10.1093/nar/gkt042.
|
Structural insights into risc assembly facilitated by
dsrna binding domains of human RNA helicase (dhx9) .
SNAP output
|
|
3vyy
|
hydrolase-RNA |
X-ray (2.9 Å) |
Fu Q, Yuan YA |
(2013) "Structural
insights into RISC assembly facilitated by
dsRNA-binding domains of human RNA helicase A
(DHX9)." Nucleic Acids Res.,
41, 3457-3470. doi: 10.1093/nar/gkt042.
|
Structural insights into risc assembly facilitated by
dsrna binding domains of human RNA helicase a (dhx9) .
SNAP output
|
|
3w1k
|
transferase-RNA |
X-ray (7.5 Å) |
Itoh Y, Brocker MJ, Sekine S, Hammond G, Suetsugu S,
Soll D, Yokoyama S |
(2013) "Decameric
SelA-tRNA(Sec) ring structure reveals mechanism of
bacterial selenocysteine formation."
Science, 340, 75-78. doi:
10.1126/science.1229521.
|
Crystal structure of the selenocysteine synthase sela
and trnasec complex . SNAP output
|
|
3w3s
|
ligase-RNA |
X-ray (3.095 Å) |
Itoh Y, Sekine S, Suetsugu S, Yokoyama S |
(2013) "Tertiary
structure of bacterial selenocysteine tRNA."
Nucleic Acids Res., 41,
6729-6738. doi: 10.1093/nar/gkt321.
|
Crystal structure of a. aeolicus trnasec in complex
with m. kandleri serrs . SNAP output
|
|
3wbm
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Guo L, Ding J, Guo R, Hou Y, Wang DC, Huang L |
(2014) "Biochemical
and structural insights into RNA binding by Ssh10b, a
member of the highly conserved Sac10b protein family in
Archaea." J.Biol.Chem.,
289, 1478-1490. doi: 10.1074/jbc.M113.521351.
|
Crystal structure of protein-RNA complex . SNAP output
|
|
3wc1
|
transferase-RNA |
X-ray (4.18 Å) |
Nakamura A, Nemoto T, Heinemann IU, Yamashita K,
Sonoda T, Komoda K, Tanaka I, Soll D, Yao M |
(2013) "Structural
basis of reverse nucleotide polymerization."
Proc.Natl.Acad.Sci.USA, 110,
20970-20975. doi: 10.1073/pnas.1321312111.
|
Crystal structure of c. albicans trna(his)
guanylyltransferase (thg1) with a g-1 deleted trna(his)
. SNAP output
|
|
3wc2
|
transferase-RNA |
X-ray (3.641 Å) |
Nakamura A, Nemoto T, Heinemann IU, Yamashita K,
Sonoda T, Komoda K, Tanaka I, Soll D, Yao M |
(2013) "Structural
basis of reverse nucleotide polymerization."
Proc.Natl.Acad.Sci.USA, 110,
20970-20975. doi: 10.1073/pnas.1321312111.
|
Crystal structure of c. albicans trna(his)
guanylyltransferase (thg1) with a trna(phe)(gug) .
SNAP output
|
|
3wfq
|
transferase-RNA |
X-ray (3.619 Å) |
Yamashita S, Takeshita D, Tomita K |
(2014) "Translocation
and rotation of tRNA during template-independent RNA
polymerization by tRNA nucleotidyltransferase."
Structure, 22, 315-325. doi:
10.1016/j.str.2013.12.002.
|
Trna processing enzyme complex 1 . SNAP output
|
|
3wfr
|
transferase-RNA |
X-ray (3.501 Å) |
Yamashita S, Takeshita D, Tomita K |
(2014) "Translocation
and rotation of tRNA during template-independent RNA
polymerization by tRNA nucleotidyltransferase."
Structure, 22, 315-325. doi:
10.1016/j.str.2013.12.002.
|
Trna processing enzyme complex 2 . SNAP output
|
|
3wfs
|
transferase-RNA |
X-ray (3.311 Å) |
Yamashita S, Takeshita D, Tomita K |
(2014) "Translocation
and rotation of tRNA during template-independent RNA
polymerization by tRNA nucleotidyltransferase."
Structure, 22, 315-325. doi:
10.1016/j.str.2013.12.002.
|
Trna processing enzyme complex 3 . SNAP output
|
|
3wqy
|
ligase-RNA |
X-ray (3.3 Å) |
Naganuma M, Sekine S, Chong YE, Guo M, Yang XL,
Gamper H, Hou YM, Schimmel P, Yokoyama S |
(2014) "The
selective tRNA aminoacylation mechanism based on a
single G.U pair." Nature,
510, 507-511. doi: 10.1038/nature13440.
|
Crystal structure of archaeoglobus fulgidus alanyl-trna
synthetase in complex with wild-type trna(ala) having
g3.u70 . SNAP output
|
|
3wqz
|
ligase-RNA |
X-ray (3.489 Å) |
Naganuma M, Sekine S, Chong YE, Guo M, Yang XL,
Gamper H, Hou YM, Schimmel P, Yokoyama S |
(2014) "The
selective tRNA aminoacylation mechanism based on a
single G.U pair." Nature,
510, 507-511. doi: 10.1038/nature13440.
|
Crystal structure of archaeoglobus fulgidus alanyl-trna
synthetase in complex with a trna(ala) variant having
a3.u70 . SNAP output
|
|
3wzi
|
transcription-RNA |
X-ray (2.9 Å) |
Yan X, Guo W, Yuan YA |
(2015) "Crystal
structures of CRISPR-associated Csx3 reveal a
manganese-dependent deadenylation exoribonuclease."
Rna Biol., 12, 749-760. doi:
10.1080/15476286.2015.1051300.
|
Crystal structure of afcsx3 in complex with ssrna .
SNAP output
|
|
3zc0
|
hydrolase-RNA |
X-ray (2.982 Å) |
Parizotto EA, Lowe ED, Parker JS |
(2013) "Structural
Basis for Duplex RNA Recognition and Cleavage by
Archaeoglobus Fulgidus C3Po."
Nat.Struct.Mol.Biol., 20,
380. doi: 10.1038/NSMB.2487.
|
Structure of afc3po - duplex RNA complex . SNAP output
|
|
3zd6
|
hydrolase-RNA |
X-ray (2.8 Å) |
Kohlway A, Luo D, Rawling DC, Ding SC, Pyle AM |
(2013) "Defining
the Functional Determinants for RNA Surveillance by
Rig-I." Embo Rep., 14,
772. doi: 10.1038/EMBOR.2013.108.
|
Snapshot 1 of rig-i scanning on RNA duplex . SNAP output
|
|
3zd7
|
hydrolase-RNA |
X-ray (2.5 Å) |
Kohlway A, Luo D, Rawling DC, Ding SC, Pyle AM |
(2013) "Defining
the Functional Determinants for RNA Surveillance by
Rig-I." Embo Rep., 14,
772. doi: 10.1038/EMBOR.2013.108.
|
Snapshot 3 of rig-i scanning on RNA duplex . SNAP output
|
|
3zjt
|
ligase-RNA |
X-ray (2.2 Å) |
Hernandez V, Crepin T, Palencia A, Cusack S, Akama T,
Baker SJ, Bu W, Feng L, Freund YR, Liu L, Meewan M, Mohan
M, Mao W, Rock FL, Sexton H, Sheoran A, Zhang Y, Zhang Y,
Zhou Y, Nieman JA, Anugula MR, Keramane EM, Savariraj K,
Reddy DS, Sharma R, Subedi R, Singh R, O'Leary A, Simon
NL, De Marsh PL, Mushtaq S, Warner M, Livermore DM, Alley
MRK, Plattner JJ |
(2013) "Discovery
of a Novel Class of Boron-Based Antibacterials with
Activity Against Gram-Negative Bacteria."
Antimicrob.Agents Chemother.,
57, 1394. doi: 10.1128/AAC.02058-12.
|
Ternary complex of e.coli leucyl-trna synthetase,
trna(leu)574 and the benzoxaborole an3017 in the
editing conformation . SNAP output
|
|
3zju
|
ligase-RNA |
X-ray (2.4 Å) |
Hernandez V, Crepin T, Palencia A, Cusack S, Akama T,
Baker SJ, Bu W, Feng L, Freund YR, Liu L, Meewan M, Mohan
M, Mao W, Rock FL, Sexton H, Sheoran A, Zhang Y, Zhang Y,
Zhou Y, Nieman JA, Anugula MR, Keramane EM, Savariraj K,
Reddy DS, Sharma R, Subedi R, Singh R, O'Leary A, Simon
NL, De Marsh PL, Mushtaq S, Warner M, Livermore DM, Alley
MRK, Plattner JJ |
(2013) "Discovery
of a Novel Class of Boron-Based Antibacterials with
Activity Against Gram-Negative Bacteria."
Antimicrob.Agents Chemother.,
57, 1394. doi: 10.1128/AAC.02058-12.
|
Ternary complex of e .coli leucyl-trna synthetase,
trna(leu) and the benzoxaborole an3016 in the editing
conformation . SNAP
output
|
|
3zjv
|
ligase-RNA |
X-ray (2.31 Å) |
Hernandez V, Crepin T, Palencia A, Cusack S, Akama T,
Baker SJ, Bu W, Feng L, Freund YR, Liu L, Meewan M, Mohan
M, Mao W, Rock FL, Sexton H, Sheoran A, Zhang Y, Zhang Y,
Zhou Y, Nieman JA, Anugula MR, Keramane EM, Savariraj K,
Reddy DS, Sharma R, Subedi R, Singh R, O'Leary A, Simon
NL, De Marsh PL, Mushtaq S, Warner M, Livermore DM, Alley
MRK, Plattner JJ |
(2013) "Discovery
of a Novel Class of Boron-Based Antibacterials with
Activity Against Gram-Negative Bacteria."
Antimicrob.Agents Chemother.,
57, 1394. doi: 10.1128/AAC.02058-12.
|
Ternary complex of e .coli leucyl-trna synthetase,
trna(leu) and the benzoxaborole an3213 in the editing
conformation . SNAP
output
|
|
3zla
|
viral protein-RNA |
X-ray (3.2 Å) |
Ariza A, Tanner SJ, Walter CT, Dent KC, Shepherd DA,
Wu W, Matthews SV, Hiscox JA, Green TJ, Luo M, Elliott
RM, Fooks AR, Ashcroft AE, Stonehouse NJ, Ranson NA, Barr
JN, Edwards TA |
(2013) "Nucleocapsid
Protein Structures from Orthobunyaviruses Reveal
Insight Into Ribonucleoprotein Architecture and RNA
Polymerization." Nucleic Acids Res.,
41, 5912. doi: 10.1093/NAR/GKT268.
|
Crystal structure of the nucleocapsid protein from
bunyamwera virus bound to RNA . SNAP output
|
|
3zn8
|
protein transport |
cryo-EM (12.0 Å) |
Von Loeffelholz O, Knoops K, Ariosa A, Zhang X,
Karuppasamy M, Huard K, Schoehn G, Berger I, Shan SO,
Schaffitzel C |
(2013) "Structural
Basis of Signal Sequence Surveillance and Selection by
the Srp-Sr Complex." Nat.Struct.Mol.Biol.,
20, 604. doi: 10.1038/NSMB.2546.
|
Structural basis of signal sequence surveillance and
selection by the srp-sr complex . SNAP output
|
|
484d
|
RNA binding protein-RNA |
NMR |
Ye X, Gorin A, Frederick R, Hu W, Majumdar A, Xu W,
McLendon G, Ellington A, Patel DJ |
(1999) "RNA
architecture dictates the conformations of a bound
peptide." Chem.Biol., 6,
657-669. doi: 10.1016/S1074-5521(99)80117-3.
|
Solution structure of hiv-1 rev peptide-RNA aptamer
complex . SNAP
output
|
|
4a2i
|
ribosome-hydrolase |
cryo-EM (16.5 Å) |
Jomaa A, Stewart G, Mears JA, Kireeva I, Brown ED,
Ortega J |
(2011) "Cryo-Electron
Microscopy Structure of the 30S Subunit in Complex with
the Yjeq Biogenesis Factor." RNA,
17, 2026. doi: 10.1261/RNA.2922311.
|
Cryo-electron microscopy structure of the 30s subunit
in complex with the yjeq biogenesis factor . SNAP output
|
|
4a2x
|
RNA binding protein-RNA |
X-ray (4.0 Å) |
Kowalinski E, Lunardi T, McCarthy AA, Louber J,
Brunel J, Grigorov B, Gerlier D, Cusack S |
(2011) "Structural
basis for the activation of innate immune
pattern-recognition receptor RIG-I by viral RNA."
Cell, 147, 423-435. doi:
10.1016/j.cell.2011.09.039.
|
Structure of duck rig-i c-terminal domain (ctd) with
14-mer dsrna . SNAP
output
|
|
4a36
|
RNA binding protein-RNA |
X-ray (3.7 Å) |
Kowalinski E, Lunardi T, Mccarthy AA, Louber J,
Brunel J, Grigorov B, Gerlier D, Cusack S |
(2011) "Structural
Basis for the Activation of Innate Immune Pattern
Recognition Receptor Rig-I by Viral RNA."
Cell(Cambridge,Mass.), 147,
423. doi: 10.1016/J.CELL.2011.09.039.
|
Structure of duck rig-i helicase domain bound to 19-mer
dsrna and atp transition state analogue . SNAP output
|
|
4adv
|
translation |
cryo-EM (13.5 Å) |
Boehringer D, O'Farrell HC, Rife JP, Ban N |
(2012) "Structural
Insights Into Methyltransferase Ksga Function in 30S
Ribosomal Subunit Biogenesis."
J.Biol.Chem., 287,
10453-10459. doi: 10.1074/JBC.M111.318121.
|
Structure of the e. coli methyltransferase ksga bound
to the e. coli 30s ribosomal subunit . SNAP output
|
|
4afy
|
hydrolase |
X-ray (2.01 Å) |
Robert-Paganin J, Nonin-Lecomte S, Rety S |
(2012) "Crystal
Structure of an Eal Domain in Complex with Reaction
Product 5'-Pgpg." Plos One,
7, 52424. doi: 10.1371/JOURNAL.PONE.0052424.
|
Crystal structure of the fimx eal domain in complex
with reaction product pgpg . SNAP output
|
|
4al6
|
hydrolase-RNA |
X-ray (2.63 Å) |
Haurwitz RE, Sternberg SH, Doudna JA |
(2012) "Csy4
Relies on an Unusual Catalytic Dyad to Position and
Cleave Crispr RNA." Embo J.,
31, 2824. doi: 10.1038/EMBOJ.2012.107.
|
Crystal structure of the s148acsy4-crrna complex .
SNAP output
|
|
4al7
|
hydrolase-RNA |
X-ray (2.32 Å) |
Haurwitz RE, Sternberg SH, Doudna JA |
(2012) "Csy4
Relies on an Unusual Catalytic Dyad to Position and
Cleave Crispr RNA." Embo J.,
31, 2824. doi: 10.1038/EMBOJ.2012.10.
|
Crystal structure of the csy4-minimal crrna complex .
SNAP output
|
|
4alp
|
chaperone-RNA |
X-ray (1.48 Å) |
Mayr F, Schutz A, Doge N, Heinemann U |
(2012) "The
Lin28 Cold-Shock Domain Remodels Pre-Let-7
Microrna." Nucleic Acids Res.,
40, 7492. doi: 10.1093/NAR/GKS355.
|
The lin28b cold shock domain in complex with
hexauridine . SNAP
output
|
|
4ang
|
virus |
X-ray (3.5 Å) |
Persson M, Tars K, Liljas L |
(2013) "Prr1
Coat Protein Binding to its RNA Translational
Operator." Acta Crystallogr.,Sect.D,
69, 367. doi: 10.1107/S0907444912047464.
|
Small RNA phage prr1 in complex with an RNA operator
fragment . SNAP
output
|
|
4aq7
|
ligase-RNA |
X-ray (2.5 Å) |
Palencia A, Crepin T, Vu MT, Lincecum Jr TL, Martinis
SA, Cusack S |
(2012) "Structural
Dynamics of the Aminoacylation and Proofreading
Functional Cycle of Bacterial Leucyl-tRNA
Synthetase." Nat.Struct.Mol.Biol.,
19, 677. doi: 10.1038/NSMB.2317.
|
Ternary complex of e. coli leucyl-trna synthetase,
trna(leu) and leucyl-adenylate analogue in the
aminoacylation conformation . SNAP output
|
|
4aqy
|
ribosome |
X-ray (3.5 Å) |
Matt T, Ng CL, Lang K, Sha SH, Akbergenov R,
Shcherbakov D, Meyer M, Duscha S, Xie J, Dubbaka SR,
Perez-Fernandez D, Vasella A, Ramakrishnan V, Schacht J,
Bottger EC |
(2012) "Dissociation
of Antibacterial Activity and Aminoglycoside
Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine
Apramycin." Proc.Natl.Acad.Sci.USA,
109, 10984. doi: 10.1073/PNAS.1204073109.
|
Structure of ribosome-apramycin complexes . SNAP output
|
|
4arc
|
ligase-RNA |
X-ray (2.0 Å) |
Palencia A, Crepin T, Vu MT, Lincecum Jr TL, Martinis
SA, Cusack S |
(2012) "Structural
Dynamics of the Aminoacylation and Proofreading
Functional Cycle of Bacterial Leucyl-tRNA
Synthetase." Nat.Struct.Mol.Biol.,
19, 677. doi: 10.1038/NSMB.2317.
|
Ternary complex of e. coli leucyl-trna synthetase,
trna(leu) and leucine in the editing conformation .
SNAP output
|
|
4ari
|
ligase-RNA |
X-ray (2.08 Å) |
Palencia A, Crepin T, Vu MT, Lincecum Jr TL, Martinis
SA, Cusack S |
(2012) "Structural
Dynamics of the Aminoacylation and Proofreading
Functional Cycle of Bacterial Leucyl-tRNA
Synthetase." Nat.Struct.Mol.Biol.,
19, 677. doi: 10.1038/NSMB.2317.
|
Ternary complex of e. coli leucyl-trna synthetase,
trna(leu) and the benzoxaborole an2679 in the editing
conformation . SNAP
output
|
|
4as1
|
ligase-RNA |
X-ray (2.02 Å) |
Palencia A, Crepin T, Vu MT, Lincecum Jr TL, Martinis
SA, Cusack S |
(2012) "Structural
Dynamics of the Aminoacylation and Proofreading
Functional Cycle of Bacterial Leucyl-tRNA
Synthetase." Nat.Struct.Mol.Biol.,
19, 677. doi: 10.1038/NSMB.2317.
|
Ternary complex of e. coli leucyl-trna synthetase,
trna(leu) and the benzoxaborole an2679 in the editing
conformation . SNAP
output
|
|
4ato
|
toxin-antitoxin |
X-ray (2.2 Å) |
Short FL, Pei XY, Blower TR, Ong SL, Fineran PC,
Luisi BF, Salmond GPC |
(2013) "Selectivity
and Self-Assembly in the Control of a Bacterial Toxin
by an Antitoxic Noncoding RNA Pseudoknot."
Proc.Natl.Acad.Sci.USA, 110,
E241. doi: 10.1073/PNAS.1216039110.
|
New insights into the mechanism of bacterial type iii
toxin-antitoxin systems: selective toxin inhibition by
a non-coding RNA pseudoknot . SNAP output
|
|
4ay2
|
hydrolase-RNA |
X-ray (2.8 Å) |
Luo D, Kohlway A, Vela A, Pyle AM |
(2012) "Visualizing
the Determinants of Viral RNA Recognition by Innate
Immune Sensor Rig-I." Structure,
20, 1983. doi: 10.1016/J.STR.2012.08.029.
|
Capturing 5' tri-phosphorylated RNA duplex by rig-i .
SNAP output
|
|
4b3g
|
hydrolase-RNA |
X-ray (2.85 Å) |
Lim SC, Bowler MW, Lai TF, Song H |
(2012) "The
Ighmbp2 Helicase Structure Reveals the Molecular Basis
for Disease-Causing Mutations in Dmsa1."
Nucleic Acids Res., 40,
11009. doi: 10.1093/NAR/GKS792.
|
Crystal structure of ighmbp2 helicase in complex with
RNA . SNAP output
|
|
4b3m
|
ribosome |
X-ray (2.9 Å) |
Perez-Fernandez D, Shcherbakov D, Matt T, Leong NC,
Kudyba I, Duscha S, Boukari H, Patak R, Dubakka SR, Lang
K, Meyer M, Akbergenov R, Freihofer P, Vaddi S, Thommes
P, Ramakrishnan V, Vasella A, Bottger EC |
(2014) "4'-O-Substitutions
Determine Selectivity of Aminoglycoside
Antibiotics." Nat.Commun.,
5, 3112. doi: 10.1038/NCOMMS4112.
|
Crystal structure of the 30s ribosome in complex with
compound 1 . SNAP
output
|
|
4b3r
|
ribosome |
X-ray (3.0 Å) |
Perez-Fernandez D, Shcherbakov D, Matt T, Leong NC,
Kudyba I, Duscha S, Boukari H, Patak R, Dubakka SR, Lang
K, Meyer M, Akbergenov R, Freihofer P, Vaddi S, Thommes
P, Ramakrishnan V, Vasella A, Bottger EC |
(2014) "4'-O-Substitutions
Determine Selectivity of Aminoglycoside
Antibiotics." Nat.Commun.,
5, 3112. doi: 10.1038/NCOMMS4112.
|
Crystal structure of the 30s ribosome in complex with
compound 30 . SNAP
output
|
|
4b3s
|
ribosome |
X-ray (3.15 Å) |
Perez-Fernandez D, Shcherbakov D, Matt T, Leong NC,
Kudyba I, Duscha S, Boukari H, Patak R, Dubakka SR, Lang
K, Meyer M, Akbergenov R, Freihofer P, Vaddi S, Thommes
P, Ramakrishnan V, Vasella A, Bottger EC |
(2014) "4'-O-Substitutions
Determine Selectivity of Aminoglycoside
Antibiotics." Nat.Commun.,
5, 3112. doi: 10.1038/NCOMMS4112.
|
Crystal structure of the 30s ribosome in complex with
compound 37 . SNAP
output
|
|
4b3t
|
ribosome |
X-ray (3.0 Å) |
Perez-Fernandez D, Shcherbakov D, Matt T, Leong NC,
Kudyba I, Duscha S, Boukari H, Patak R, Dubakka SR, Lang
K, Meyer M, Akbergenov R, Freihofer P, Vaddi S, Thommes
P, Ramakrishnan V, Vasella A, Bottger EC |
(2014) "4'-O-Substitutions
Determine Selectivity of Aminoglycoside
Antibiotics." Nat.Commun.,
5, 3112. doi: 10.1038/NCOMMS4112.
|
Crystal structure of the 30s ribosome in complex with
compound 39 . SNAP
output
|
|
4b8t
|
transcription-RNA |
NMR |
Nicastro G, Garcia-Mayoral MF, Hollingworth D, Kelly
G, Martin SR, Briata P, Gherzi R, Ramos A |
(2012) "Noncanonical
G Recognition Mediates Ksrp Regulation of Let-7
Biogenesis." Nat.Struct.Mol.Biol.,
19, 1282. doi: 10.1038/NSMB.2427.
|
RNA binding protein solution structure of the third kh
domain of ksrp in complex with the g-rich target
sequence. . SNAP
output
|
|
4ba2
|
hydrolase-RNA |
X-ray (2.501 Å) |
Lorentzen E, Conti E |
(2012) "Crystal
Structure of a 9-Subunit Archaeal Exosome in
Pre-Catalytic States of the Phosphorolytic
Reaction." Archaea, 2012,
21869. doi: 10.1155/2012/721869.
|
Archaeal exosome (rrp4-rrp41(d182a)-rrp42) bound to
inorganic phosphate . SNAP output
|
|
4bhh
|
viral protein-RNA |
X-ray (3.4 Å) |
Reguera J, Malet H, Weber F, Cusack S |
(2013) "Structural
Basis for Encapsidation of Genomic RNA by La Crosse
Orthobunyavirus Nucleoprotein."
Proc.Natl.Acad.Sci.USA, 110,
7246. doi: 10.1073/PNAS.1302298110.
|
Crystal structure of tetramer of la crosse virus
nucleoprotein in complex with ssrna . SNAP output
|
|
4bkk
|
viral protein-RNA |
cryo-EM |
Bakker SE, Duquerroy S, Galloux M, Loney C, Conner E,
Eleouet JF, Rey FA, Bhella D |
(2013) "The
Respiratory Syncytial Virus Nucleoprotein-RNA Complex
Forms a Left-Handed Helical Nucleocapsid."
J.Gen.Virol., 94, 1734. doi:
10.1099/VIR.0.053025-0.
|
The respiratory syncytial virus nucleoprotein-RNA
complex forms a left-handed helical nucleocapsid. .
SNAP output
|
|
4bpb
|
hydrolase-RNA |
X-ray (2.584 Å) |
Luo D, Ding SC, Vela A, Kohlway A, Lindenbach BD,
Pyle AM |
(2011) "Structural
Insights Into RNA Recognition by Rig-I."
Cell(Cambridge,Mass.), 147,
409. doi: 10.1016/J.CELL.2011.09.023.
|
Structural insights into RNA recognition by rig-i .
SNAP output
|
|
4bs2
|
transcription |
NMR |
Lukavsky PJ, Daujotyte D, Tollervey JR, Ule J, Stuani
C, Buratti E, Baralle FE, Damberger FF, Allain FHT |
(2013) "Molecular
Basis of Ug-Rich RNA Recognition by the Human Splicing
Factor Tdp-43." Nat.Struct.Mol.Biol.,
20, 1443. doi: 10.1038/NSMB.2698.
|
NMR structure of human tdp-43 tandem rrms in complex
with ug-rich RNA . SNAP
output
|
|
4bts
|
ribosome |
X-ray (3.703 Å) |
Weisser M, Voigts-Hoffmann F, Rabl J, Leibundgut M,
Ban N |
(2013) "The
crystal structure of the eukaryotic 40S ribosomal
subunit in complex with eIF1 and eIF1A." Nat.
Struct. Mol. Biol., 20,
1015-1017. doi: 10.1038/nsmb.2622.
|
The crystal structure of the eukaryotic 40s ribosomal
subunit in complex with eif1 and eif1a . SNAP output
|
|
4bw0
|
RNA-RNA binding protein |
X-ray (2.33 Å) |
Huang L, Lilley DMJ |
(2013) "The
Molecular Recognition of Kink-Turn Structure by the
L7Ae Class of Proteins." RNA,
19, 1703. doi: 10.1261/RNA.041517.113.
|
The molecular recognition of kink turn structure by the
l7ae class of proteins . SNAP output
|
|
4by9
|
transferase-RNA |
NMR |
Lapinaite A, Simon B, Skjaerven L, Rakwalska-Bange M,
Gabel F, Carlomagno T |
(2013) "The
Structure of the Box C/D Enzyme Reveals Regulation of
RNA Methylation." Nature,
502, 519. doi: 10.1038/NATURE12581.
|
The structure of the box cd enzyme reveals regulation
of rrna methylation . SNAP output
|
|
4c4w
|
RNA binding protein-RNA |
X-ray (2.95 Å) |
Huang L, Lilley DMJ |
(2014) "Structure
of a Rare, Non-Standard Sequence K-Turn Bound by L7Ae
Protein." Nucleic Acids Res.,
42, 4734. doi: 10.1093/NAR/GKU087.
|
Structure of a rare, non-standard sequence k-turn bound
by l7ae protein . SNAP
output
|
|
4c7o
|
nuclear protein-RNA |
X-ray (2.6 Å) |
Voigts-Hoffmann F, Schmitz N, Shen K, Shan SO, Ataide
SF, Ban N |
(2013) "The
Structural Basis of Ftsy Recruitment and Gtpase
Activation by Srp RNA." Mol.Cell,
52, 643. doi: 10.1016/J.MOLCEL.2013.10.005.
|
The structural basis of ftsy recruitment and gtpase
activation by srp RNA . SNAP output
|
|
4c8z
|
hydrolase-RNA |
X-ray (2.503 Å) |
Niewoehner O, Jinek M, Doudna JA |
(2014) "Evolution
of Crispr RNA Recognition and Processing by Cas6
Endonucleases." Nucleic Acids Res.,
42, 1341. doi: 10.1093/NAR/GKT922.
|
Cas6 (ttha0078) product complex . SNAP output
|
|
4c9d
|
hydrolase-RNA |
X-ray (3.0 Å) |
Niewoehner O, Jinek M, Doudna JA |
(2014) "Evolution
of CRISPR RNA recognition and processing by Cas6
endonucleases." Nucleic Acids Res.,
42, 1341-1353. doi: 10.1093/nar/gkt922.
|
Cas6 (tthb231) product complex . SNAP output
|
|
4ce4
|
ribosome |
cryo-EM (4.9 Å) |
Greber BJ, Boehringer D, Leitner A, Bieri P,
Voigts-Hoffmann F, Erzberger JP, Leibundgut M, Aebersold
R, Ban N |
(2014) "Architecture
of the Large Subunit of the Mammalian Mitochondrial
Ribosome." Nature, 505,
515. doi: 10.1038/NATURE12890.
|
39s large subunit of the porcine mitochondrial ribosome
. SNAP output
|
|
4cio
|
RNA binding protein-RNA |
NMR |
Amrane S, Rebora K, Zniber I, Dupuy D, Mackereth
CD |
(2014) "Backbone-Independent
Nucleic Acid Binding by Splicing Factor Sup-12 Reveals
Key Aspects of Molecular Recognition."
Nat.Commun., 5, 4595. doi:
10.1038/NCOMMS5595.
|
Rrm domain from c. elegans sup-12 bound to ggugugc RNA
. SNAP output
|
|
4cqn
|
ligase-RNA |
X-ray (2.5 Å) |
Cvetesic N, Palencia A, Halasz I, Cusack S,
Gruic-Sovulj I |
(2014) "The
Physiological Target for Leurs Translational Quality
Control is Norvaline." Embo J.,
33, 1639. doi: 10.15252/EMBJ.201488199.
|
Crystal structure of the e.coli leurs-trna complex with
the non- cognate isoleucyl adenylate analogue .
SNAP output
|
|
4csf
|
viral protein-RNA |
X-ray (2.598 Å) |
Olal D, Dick A, Woods VL, Liu T, Li S, Devignot S,
Weber F, Saphire EO, Daumke O |
(2014) "Structural
Insights Into RNA Encapsidation and Helical Assembly of
the Toscana Virus Nucleoprotein." Nucleic Acids
Res., 42, 6025. doi: 10.1093/NAR/GKU229.
|
Structural insights into toscana virus RNA
encapsidation . SNAP
output
|
|
4csu
|
ribosome |
cryo-EM (5.5 Å) |
Feng B, Mandava CS, Guo Q, Wang J, Cao W, Li N, Zhang
Y, Zhang Y, Wang Z, Wu J, Sanyal S, Lei J, Gao N |
(2014) "Structural
and Functional Insights Into the Mode of Action of a
Universally Conserved Obg Gtpase." Plos
Biol., 12, 1866. doi: 10.1371/JOURNAL.PBIO.1001866.
|
cryo-EM structures of the 50s ribosome subunit bound
with obge . SNAP
output
|
|
4cxg
|
translation |
cryo-EM (8.7 Å) |
Budkevich TV, Giesebrecht J, Behrmann E, Loerke J,
Ramrath DJ, Mielke T, Ismer J, Hildebrand PW, Tung CS,
Nierhaus KH, Sanbonmatsu KY, Spahn CM |
(2014) "Regulation
of the Mammalian Elongation Cycle by Subunit Rolling: A
Eukaryotic-Specific Ribosome Rearrangement."
Cell(Cambridge,Mass.), 158,
121. doi: 10.1016/J.CELL.2014.04.044.
|
Regulation of the mammalian elongation cycle by 40s
subunit rolling: a eukaryotic-specific ribosome
rearrangement . SNAP
output
|
|
4cxh
|
translation |
cryo-EM (8.9 Å) |
Budkevich TV, Giesebrecht J, Behrmann E, Loerke J,
Ramrath DJ, Mielke T, Ismer J, Hildebrand PW, Tung CS,
Nierhaus KH, Sanbonmatsu KY, Spahn CM |
(2014) "Regulation
of the Mammalian Elongation Cycle by Subunit Rolling: A
Eukaryotic-Specific Ribosome Rearrangement."
Cell(Cambridge,Mass.), 158,
121. doi: 10.1016/J.CELL.2014.04.044.
|
Regulation of the mammalian elongation cycle by 40s
subunit rolling: a eukaryotic-specific ribosome
rearrangement . SNAP
output
|
|
4d25
|
hydrolase |
X-ray (1.9 Å) |
Xiol J, Spinelli P, Laussmann MA, Homolka D, Yang Z,
Cora E, Coute Y, Conn S, Kadlec J, Sachidanandam R,
Kaksonen M, Cusack S, Ephrussi A, Pillai RS |
(2014) "RNA
Clamping by Vasa Assembles a Pirna Amplifier Complex on
Transposon Transcripts."
Cell(Cambridge,Mass.), 157,
1698. doi: 10.1016/J.CELL.2014.05.018.
|
Crystal structure of the bombyx mori vasa helicase
(e339q) in complex with RNA and amppnp . SNAP output
|
|
4d26
|
hydrolase |
X-ray (2.1 Å) |
Xiol J, Spinelli P, Laussmann MA, Homolka D, Yang Z,
Cora E, Coute Y, Conn S, Kadlec J, Sachidanandam R,
Kaksonen M, Cusack S, Ephrussi A, Pillai RS |
(2014) "RNA
Clamping by Vasa Assembles a Pirna Amplifier Complex on
Transposon Transcripts."
Cell(Cambridge,Mass.), 157,
1698. doi: 10.1016/J.CELL.2014.05.018.
|
Crystal structure of the bombyx mori vasa helicase
(e339q) in complex with RNA,adp and pi . SNAP output
|
|
4d5l
|
ribosome |
cryo-EM (9.0 Å) |
Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu
KY, Pestova TV, Spahn CMT |
(2015) "Cryo-Em
of Ribosomal 80S Complexes with Termination Factors
Reveals the Translocated Cricket Paralysis Virus
Ires." Mol.Cell, 57, 422.
doi: 10.1016/J.MOLCEL.2014.12.016.
|
cryo-EM structures of ribosomal 80s complexes with
termination factors and cricket paralysis virus ires
reveal the ires in the translocated state . SNAP output
|
|
4d5n
|
ribosome-RNA |
cryo-EM (9.0 Å) |
Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu
KY, Pestova TV, Spahn CMT |
(2015) "Cryo-Em
of Ribosomal 80S Complexes with Termination Factors
Reveals the Translocated Cricket Paralysis Virus
Ires." Mol.Cell, 57, 422.
doi: 10.1016/J.MOLCEL.2014.12.016.
|
cryo-EM structures of ribosomal 80s complexes with
termination factors and cricket paralysis virus ires
reveal the ires in the translocated state . SNAP output
|
|
4d5y
|
ribosome |
cryo-EM (9.0 Å) |
Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu
KY, Pestova TV, Spahn CMT |
(2015) "Cryo-Em
Structures of Ribosomal 80S Complexes with Termination
Factors and Cricket Paralysis Virus Ires Reveal the
Ires in the Translocated State." Mol.Cell,
57, 422. doi: 10.1016/J.MOLCEL.2014.12.016.
|
cryo-EM structures of ribosomal 80s complexes with
termination factors and cricket paralysis virus ires
reveal the ires in the translocated state . SNAP output
|
|
4d61
|
ribosome |
cryo-EM (9.0 Å) |
Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu
KY, Pestova TV, Spahn CMT |
(2015) "Cryo-Em
of Ribosomal 80S Complexes with Termination Factors
Reveals the Translocated Cricket Paralysis Virus
Ires." Mol.Cell, 57, 422.
doi: 10.1016/J.MOLCEL.2014.12.016.
|
cryo-EM structures of ribosomal 80s complexes with
termination factors and cricket paralysis virus ires
reveal the ires in the translocated state . SNAP output
|
|
4d67
|
ribosome |
cryo-EM (9.0 Å) |
Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu
KY, Pestova TV, Spahn CMT |
(2015) "Cryo-Em
Structures of Ribosomal 80S Complexes with Termination
Factors and Cricket Paralysis Virus Ires Reveal the
Ires in the Translocated State." Mol.Cell,
57, 422. doi: 10.1016/J.MOLCEL.2014.12.016.
|
cryo-EM structures of ribosomal 80s complexes with
termination factors and cricket paralysis virus ires
reveal the ires in the translocated state . SNAP output
|
|
4db2
|
RNA binding protein-RNA |
X-ray (3.157 Å) |
Mallam AL, Del Campo M, Gilman B, Sidote DJ,
Lambowitz AM |
(2012) "Structural
basis for RNA-duplex recognition and unwinding by the
DEAD-box helicase Mss116p." Nature,
490, 121-125. doi: 10.1038/nature11402.
|
Mss116p dead-box helicase domain 2 bound to an RNA
duplex . SNAP output
|
|
4dr1
|
ribosome |
X-ray (3.6 Å) |
Demirci H, Murphy F, Murphy E, Gregory ST, Dahlberg
AE, Jogl G |
(2013) "A
structural basis for streptomycin-induced misreading of
the genetic code." Nat Commun,
4, 1355. doi: 10.1038/ncomms2346.
|
Crystal structure of the apo 30s ribosomal subunit from
thermus thermophilus (hb8) . SNAP output
|
|
4dr2
|
ribosome-antibiotic |
X-ray (3.249 Å) |
Demirci H, Murphy F, Murphy E, Gregory ST, Dahlberg
AE, Jogl G |
(2013) "A
structural basis for streptomycin-induced misreading of
the genetic code." Nat Commun,
4, 1355. doi: 10.1038/ncomms2346.
|
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with multiple copies of paromomycin
molecules bound . SNAP
output
|
|
4dr3
|
ribosome-antibiotic |
X-ray (3.348 Å) |
Demirci H, Murphy F, Murphy E, Gregory ST, Dahlberg
AE, Jogl G |
(2013) "A
structural basis for streptomycin-induced misreading of
the genetic code." Nat Commun,
4, 1355. doi: 10.1038/ncomms2346.
|
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with streptomycin bound . SNAP output
|
|
4dr4
|
ribosome-antibiotic |
X-ray (3.969 Å) |
Demirci H, Murphy F, Murphy E, Gregory ST, Dahlberg
AE, Jogl G |
(2013) "A
structural basis for streptomycin-induced misreading of
the genetic code." Nat Commun,
4, 1355. doi: 10.1038/ncomms2346.
|
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with codon, cognate transfer RNA
anticodon stem-loop and multiple copies of paromomycin
molecules bound . SNAP
output
|
|
4dr5
|
ribosome-antibiotic |
X-ray (3.45 Å) |
Demirci H, Murphy F, Murphy E, Gregory ST, Dahlberg
AE, Jogl G |
(2013) "A
structural basis for streptomycin-induced misreading of
the genetic code." Nat Commun,
4, 1355. doi: 10.1038/ncomms2346.
|
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with codon, crystallographically
disordered cognate transfer RNA anticodon stem-loop and
streptomycin bound . SNAP output
|
|
4dr6
|
ribosome-antibiotic |
X-ray (3.3 Å) |
Demirci H, Murphy F, Murphy E, Gregory ST, Dahlberg
AE, Jogl G |
(2013) "A
structural basis for streptomycin-induced misreading of
the genetic code." Nat Commun,
4, 1355. doi: 10.1038/ncomms2346.
|
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with codon, near-cognate transfer RNA
anticodon stem-loop mismatched at the first codon
position and streptomycin bound . SNAP output
|
|
4dr7
|
ribosome-antibiotic |
X-ray (3.75 Å) |
Demirci H, Murphy F, Murphy E, Gregory ST, Dahlberg
AE, Jogl G |
(2013) "A
structural basis for streptomycin-induced misreading of
the genetic code." Nat Commun,
4, 1355. doi: 10.1038/ncomms2346.
|
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with codon, crystallographically
disordered near-cognate transfer RNA anticodon
stem-loop mismatched at the second codon position, and
streptomycin bound . SNAP output
|
|
4duy
|
ribosome |
X-ray (3.386 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, u13c .
SNAP output
|
|
4duz
|
ribosome-antibiotic |
X-ray (3.651 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, u13c, bound
with streptomycin . SNAP
output
|
|
4dv0
|
ribosome |
X-ray (3.853 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, u20g .
SNAP output
|
|
4dv1
|
ribosome-antibiotic |
X-ray (3.849 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, u20g, bound
with streptomycin . SNAP
output
|
|
4dv2
|
ribosome |
X-ray (3.646 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, c912a .
SNAP output
|
|
4dv3
|
ribosome-antibiotic |
X-ray (3.547 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, c912a,
bound with streptomycin . SNAP output
|
|
4dv4
|
ribosome |
X-ray (3.651 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, a914g .
SNAP output
|
|
4dv5
|
ribosome-antibiotic |
X-ray (3.683 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, a914g,
bound with streptomycin . SNAP output
|
|
4dv6
|
ribosome |
X-ray (3.297 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, a915g .
SNAP output
|
|
4dv7
|
ribosome-antibiotic |
X-ray (3.294 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the thermus thermophilus 30s
ribosomal subunit with a 16s rrna mutation, a915g,
bound with streptomycin . SNAP output
|
|
4dw7
|
viral protein-RNA |
X-ray (3.08 Å) |
Krey T, Bontems F, Vonrhein C, Vaney MC, Bricogne G,
Rumenapf T, Rey FA |
(2012) "Crystal
Structure of the Pestivirus Envelope Glycoprotein
E(rns) and Mechanistic Analysis of Its Ribonuclease
Activity." Structure, 20,
862-873. doi: 10.1016/j.str.2012.03.018.
|
Crystal structure of an active-site mutant of the
glycoprotein erns from the pestivirus bvdv-1 in complex
with a cpu dinucleotide . SNAP output
|
|
4dwa
|
viral protein-RNA |
X-ray (3.01 Å) |
Krey T, Bontems F, Vonrhein C, Vaney MC, Bricogne G,
Rumenapf T, Rey FA |
(2012) "Crystal
Structure of the Pestivirus Envelope Glycoprotein
E(rns) and Mechanistic Analysis of Its Ribonuclease
Activity." Structure, 20,
862-873. doi: 10.1016/j.str.2012.03.018.
|
Crystal structure of an active-site mutant of the
glycoprotein erns from the pestivirus bvdv-1 in complex
with a cpupc trinucleotide . SNAP output
|
|
4dzs
|
RNA binding protein-RNA |
X-ray (3.14 Å) |
Valley CT, Porter DF, Qiu C, Campbell ZT, Hall TM,
Wickens M |
(2012) "Patterns
and plasticity in RNA-protein interactions enable
recruitment of multiple proteins through a single
site." Proc.Natl.Acad.Sci.USA,
109, 6054-6059. doi: 10.1073/pnas.1200521109.
|
Crystal structure of yeast puf4p RNA binding domain in
complex with ho-4be mutant RNA . SNAP output
|
|
4e78
|
viral protein, transferase-RNA |
X-ray (2.9 Å) |
Mosley RT, Edwards TE, Murakami E, Lam AM, Grice RL,
Du J, Sofia MJ, Furman PA, Otto MJ |
(2012) "Structure
of hepatitis C virus polymerase in complex with
primer-template RNA." J.Virol.,
86, 6503-6511. doi: 10.1128/JVI.00386-12.
|
Crystal structure of a product state assembly of hcv
ns5b genotype 2a jfh-1 isolate with beta hairpin loop
deletion bound to primer-template RNA with 3'-dg .
SNAP output
|
|
4e7a
|
viral protein, transferase-RNA |
X-ray (3.0 Å) |
Mosley RT, Edwards TE, Murakami E, Lam AM, Grice RL,
Du J, Sofia MJ, Furman PA, Otto MJ |
(2012) "Structure
of hepatitis C virus polymerase in complex with
primer-template RNA." J.Virol.,
86, 6503-6511. doi: 10.1128/JVI.00386-12.
|
Crystal structure of a product state assembly of hcv
ns5b genotype 2a jfh-1 isolate with beta hairpin
deletion bound to primer-template RNA with a 2',3'-ddc
. SNAP output
|
|
4ejt
|
transcription regulator-RNA |
X-ray (3.0 Å) |
Chang YM, Chen CK-M, Chang YC, Jeng WY, Hou MH, Wang
AH-J |
(2012) "Functional
studies of ssDNA binding ability of MarR family protein
TcaR from Staphylococcus epidermidis." Plos
One, 7, e45665. doi: 10.1371/journal.pone.0045665.
|
Staphylococcus epidermidis tcar in complex with RNA .
SNAP output
|
|
4erd
|
RNA binding protein-RNA |
X-ray (2.589 Å) |
Singh M, Wang Z, Koo BK, Patel A, Cascio D, Collins
K, Feigon J |
(2012) "Structural
Basis for Telomerase RNA Recognition and RNP Assembly
by the Holoenzyme La Family Protein p65."
Mol.Cell, 47, 16-26. doi:
10.1016/j.molcel.2012.05.018.
|
Crystal structure of the c-terminal domain of
tetrahymena telomerase protein p65 in complex with stem
iv of telomerase RNA . SNAP output
|
|
4eya
|
transcription-RNA |
X-ray (3.2 Å) |
Stagno JR, Ma B, Li J, Altieri AS, Byrd RA, Ji X |
(2012) "Crystal
structure of a plectonemic RNA supercoil." Nat
Commun, 3, 901. doi: 10.1038/ncomms1903.
|
Crystal structure of a plectonemic RNA supercoil .
SNAP output
|
|
4f02
|
translation-RNA |
X-ray (2.0 Å) |
Safaee N, Kozlov G, Noronha AM, Xie J, Wilds CJ,
Gehring K |
(2012) "Interdomain
Allostery Promotes Assembly of the Poly(A) mRNA Complex
with PABP and eIF4G." Mol.Cell,
48, 375-386. doi: 10.1016/j.molcel.2012.09.001.
|
Crystal structure of the pabp-binding site of eif4g in
complex with rrm1-2 of pabp and poly(a) . SNAP output
|
|
4f1n
|
RNA binding protein-RNA |
X-ray (3.187 Å) |
Nakanishi K, Weinberg DE, Bartel DP, Patel DJ |
(2012) "Structure
of yeast Argonaute with guide RNA."
Nature, 486, 368-374. doi:
10.1038/nature11211.
|
Crystal structure of kluyveromyces polysporus argonaute
with a guide RNA . SNAP
output
|
|
4f3t
|
hydrolase-RNA |
X-ray (2.25 Å) |
Elkayam E, Kuhn CD, Tocilj A, Haase AD, Greene EM,
Hannon GJ, Joshua-Tor L |
(2012) "The
Structure of Human Argonaute-2 in Complex with
miR-20a." Cell(Cambridge,Mass.),
150, 100-110. doi: 10.1016/j.cell.2012.05.017.
|
Human argonaute-2 - mir-20a complex . SNAP output
|
|
4fsj
|
virus |
X-ray (3.5 Å) |
Speir JA, Chen Z, Reddy VS, Johnson JE |
(2012) "Structural study of virus assembly
intermediates reveals maturation event sequence and a
staging position for externalized lytic peptides." |
Crystal structure of the virus like particle of flock
house virus . SNAP
output
|
|
4ftb
|
virus |
X-ray (2.7 Å) |
Speir JA, Chen Z, Reddy VS, Johnson JE |
(2012) "Structural study of virus assembly
intermediates reveals maturation event sequence and a
staging position for externalized lytic peptides." |
Crystal structure of the authentic flock house virus
particle . SNAP
output
|
|
4fte
|
virus |
X-ray (3.5 Å) |
Speir JA, Chen Z, Reddy VS, Johnson JE |
(2012) "Structural study of virus assembly
intermediates reveals maturation event sequence and a
staging position for externalized lytic peptides." |
Crystal structure of the d75n mutant capsid of flock
house virus . SNAP
output
|
|
4fts
|
virus |
X-ray (3.2 Å) |
Speir JA, Chen Z, Reddy VS, Johnson JE |
(2012) "Structural study of virus assembly
intermediates reveals maturation event sequence and a
staging position for externalized lytic peptides." |
Crystal structure of the n363t mutant of the flock
house virus capsid . SNAP output
|
|
4fvu
|
hydrolase-RNA |
X-ray (2.91 Å) |
Hastie KM, King LB, Zandonatti MA, Saphire EO |
(2012) "Structural
Basis for the dsRNA Specificity of the Lassa Virus NP
Exonuclease." Plos One,
7, e44211. doi: 10.1371/journal.pone.0044211.
|
Structural basis for the dsrna specificity of the lassa
virus np exonuclease . SNAP output
|
|
4fwt
|
translation, transferase-RNA |
X-ray (3.2 Å) |
Takeshita D, Yamashita S, Tomita K |
(2012) "Mechanism
for template-independent terminal adenylation activity
of Q beta replicase." Structure,
20, 1661-1669. doi: 10.1016/j.str.2012.07.004.
|
Complex structure of viral RNA polymerase form iii .
SNAP output
|
|
4g0a
|
hydrolase-RNA |
X-ray (2.1 Å) |
Hu L, Chow DC, Patton JT, Palzkill T, Estes MK,
Prasad BV |
(2012) "Crystallographic
Analysis of Rotavirus NSP2-RNA Complex Reveals Specific
Recognition of 5' GG Sequence for RTPase Activity."
J.Virol., 86, 10547-10557.
doi: 10.1128/JVI.01201-12.
|
Crystallographic analysis of rotavirus nsp2-RNA complex
reveals specific recognition of 5'-gg sequence for
rtpase activity . SNAP
output
|
|
4g9z
|
viral protein-RNA |
X-ray (2.03 Å) |
Jiang X, Huang Q, Wang W, Dong H, Ly H, Liang Y, Dong
C |
(2013) "Structures
of Arenaviral Nucleoproteins with Triphosphate dsRNA
Reveal a Unique Mechanism of Immune Suppression."
J.Biol.Chem., 288,
16949-16959. doi: 10.1074/jbc.M112.420521.
|
Lassa nucleoprotein with dsrna reveals novel mechanism
for immune suppression . SNAP output
|
|
4gcw
|
hydrolase-RNA |
X-ray (3.0 Å) |
Pellegrini O, Li de la Sierra-Gallay I, Piton J,
Gilet L, Condon C |
(2012) "Activation
of tRNA Maturation by Downstream Uracil Residues in B.
subtilis." Structure, 20,
1769-1777. doi: 10.1016/j.str.2012.08.002.
|
Crystal structure of rnase z in complex with precursor
trna(thr) . SNAP
output
|
|
4gha
|
viral protein,RNA binding protein-RNA |
X-ray (2.5 Å) |
Bale S, Julien JP, Bornholdt ZA, Kimberlin CR,
Halfmann P, Zandonatti MA, Kunert J, Kroon GJ, Kawaoka Y,
Macrae IJ, Wilson IA, Saphire EO |
(2012) "Marburg
Virus VP35 Can Both Fully Coat the Backbone and Cap the
Ends of dsRNA for Interferon Antagonism." Plos
Pathog., 8, e1002916. doi:
10.1371/journal.ppat.1002916.
|
Crystal structure of marburg virus vp35 RNA binding
domain bound to 12-bp dsrna . SNAP output
|
|
4ghl
|
transcription, viral protein-RNA |
X-ray (2.02 Å) |
Ramanan P, Edwards MR, Shabman RS, Leung DW,
Endlich-Frazier AC, Borek DM, Otwinowski Z, Liu G, Huh J,
Basler CF, Amarasinghe GK |
(2012) "Structural
basis for Marburg virus VP35-mediated immune evasion
mechanisms." Proc.Natl.Acad.Sci.USA,
109, 20661-20666. doi: 10.1073/pnas.1213559109.
|
Structural basis for marburg virus vp35 mediate immune
evasion mechanisms . SNAP output
|
|
4gkj
|
ribosome-antibiotic |
X-ray (3.298 Å) |
Cantara WA, Murphy FV, Demirci H, Agris PF |
(2013) "Expanded
use of sense codons is regulated by modified cytidines
in tRNA." Proc.Natl.Acad.Sci.USA,
110, 10964-10969. doi: 10.1073/pnas.1222641110.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a human mitochondrial anticodon
stem loop (asl) of transfer RNA methionine (trnamet)
bound to an mrna with an aug-codon in the a-site and
paromomycin. . SNAP
output
|
|
4gkk
|
ribosome-antibiotic |
X-ray (3.2 Å) |
Cantara WA, Murphy FV, Demirci H, Agris PF |
(2013) "Expanded
use of sense codons is regulated by modified cytidines
in tRNA." Proc.Natl.Acad.Sci.USA,
110, 10964-10969. doi: 10.1073/pnas.1222641110.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a human mitochondrial anticodon
stem loop (asl) of transfer RNA methionine (trnamet)
bound to an mrna with an aua-codon in the a-site and
paromomycin . SNAP
output
|
|
4gl2
|
RNA binding protein-RNA |
X-ray (3.557 Å) |
Wu B, Peisley A, Richards C, Yao H, Zeng X, Lin C,
Chu F, Walz T, Hur S |
(2013) "Structural
Basis for dsRNA Recognition, Filament Formation, and
Antiviral Signal Activation by MDA5."
Cell(Cambridge,Mass.), 152,
276-289. doi: 10.1016/j.cell.2012.11.048.
|
Structural basis for dsrna duplex backbone recognition
by mda5 . SNAP
output
|
|
4gv3
|
RNA binding protein-RNA |
X-ray (1.68 Å) |
Jiang X, Huang Q, Wang W, Dong H, Ly H, Liang Y, Dong
C |
(2013) "Structures
of Arenaviral Nucleoproteins with Triphosphate dsRNA
Reveal a Unique Mechanism of Immune Suppression."
J.Biol.Chem., 288,
16949-16959. doi: 10.1074/jbc.M112.420521.
|
Structures of lassa and tacaribe viral nucleoproteins
with or without 5 triphosphate dsrna substrate reveal a
unique 3 -5 exoribonuclease mechanism to suppress type
i interferon production . SNAP output
|
|
4gv6
|
RNA binding protein-RNA |
X-ray (1.98 Å) |
Jiang X, Huang Q, Wang W, Dong H, Ly H, Liang Y, Dong
C |
(2013) "Structures
of Arenaviral Nucleoproteins with Triphosphate dsRNA
Reveal a Unique Mechanism of Immune Suppression."
J.Biol.Chem., 288,
16949-16959. doi: 10.1074/jbc.M112.420521.
|
Structures of lassa and tacaribe viral nucleoproteins
with or without 5 triphosphate dsrna substrate reveal a
unique 3 -5 exoribonuclease mechanism to suppress type
i interferon production . SNAP output
|
|
4gv9
|
RNA binding protein-RNA |
X-ray (2.46 Å) |
Jiang X, Huang Q, Wang W, Dong H, Ly H, Liang Y, Dong
C |
(2013) "Structures
of Arenaviral Nucleoproteins with Triphosphate dsRNA
Reveal a Unique Mechanism of Immune Suppression."
J.Biol.Chem., 288,
16949-16959. doi: 10.1074/jbc.M112.420521.
|
Lassa nucleoprotein c-terminal domain in complex with
triphosphated dsrna soaking for 5 min . SNAP output
|
|
4h5o
|
viral protein-RNA |
X-ray (3.9 Å) |
Raymond DD, Piper ME, Gerrard SR, Skiniotis G, Smith
JL |
(2012) "Phleboviruses
encapsidate their genomes by sequestering RNA
bases." Proc.Natl.Acad.Sci.USA,
109, 19208-19213. doi: 10.1073/pnas.1213553109.
|
Crystal structure of rift valley fever virus
nucleocapsid protein pentamer bound to single-stranded
RNA . SNAP output
|
|
4h5p
|
viral protein-RNA |
X-ray (2.15 Å) |
Raymond DD, Piper ME, Gerrard SR, Skiniotis G, Smith
JL |
(2012) "Phleboviruses
encapsidate their genomes by sequestering RNA
bases." Proc.Natl.Acad.Sci.USA,
109, 19208-19213. doi: 10.1073/pnas.1213553109.
|
Crystal structure of rift valley fever virus
nucleocapsid protein tetramer bound to single-stranded
RNA . SNAP output
|
|
4hor
|
RNA binding protein-RNA |
X-ray (1.861 Å) |
Abbas YM, Pichlmair A, Gorna MW, Superti-Furga G,
Nagar B |
(2013) "Structural
basis for viral 5'-PPP-RNA recognition by human IFIT
proteins." Nature, 494,
60-64. doi: 10.1038/nature11783.
|
Crystal structure of full-length human ifit5 with
5`-triphosphate oligocytidine . SNAP output
|
|
4hos
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Abbas YM, Pichlmair A, Gorna MW, Superti-Furga G,
Nagar B |
(2013) "Structural
basis for viral 5'-PPP-RNA recognition by human IFIT
proteins." Nature, 494,
60-64. doi: 10.1038/nature11783.
|
Crystal structure of full-length human ifit5 with
5`-triphosphate oligouridine . SNAP output
|
|
4hot
|
RNA binding protein-RNA |
X-ray (2.501 Å) |
Abbas YM, Pichlmair A, Gorna MW, Superti-Furga G,
Nagar B |
(2013) "Structural
basis for viral 5'-PPP-RNA recognition by human IFIT
proteins." Nature, 494,
60-64. doi: 10.1038/nature11783.
|
Crystal structure of full-length human ifit5 with
5`-triphosphate oligoadenine . SNAP output
|
|
4ht8
|
RNA binding protein-RNA |
X-ray (1.9 Å) |
Wang W, Wang L, Wu J, Gong Q, Shi Y |
(2013) "Hfq-bridged
ternary complex is important for translation activation
of rpoS by DsrA." Nucleic Acids Res.,
41, 5938-5948. doi: 10.1093/nar/gkt276.
|
Crystal structure of e coli hfq bound to poly(a) a7 .
SNAP output
|
|
4ht9
|
RNA binding protein-RNA |
X-ray (1.8 Å) |
Wang W, Wang L, Wu J, Gong Q, Shi Y |
(2013) "Hfq-bridged
ternary complex is important for translation activation
of rpoS by DsrA." Nucleic Acids Res.,
41, 5938-5948. doi: 10.1093/nar/gkt276.
|
Crystal structure of e coli hfq bound to two rnas .
SNAP output
|
|
4i67
|
hydrolase-RNA |
X-ray (2.33 Å) |
Steimer L, Wurm JP, Linden MH, Rudolph MG, Wohnert J,
Klostermeier D |
(2013) "Recognition
of two distinct elements in the RNA substrate by the
RNA-binding domain of the T. thermophilus DEAD box
helicase Hera." Nucleic Acids Res.,
41, 6259-6272. doi: 10.1093/nar/gkt323.
|
Crystal structure of the rrm domain of RNA helicase
hera from t. thermophilus in complex with gggc RNA .
SNAP output
|
|
4ifd
|
hydrolase-RNA |
X-ray (2.805 Å) |
Makino DL, Baumgartner M, Conti E |
(2013) "Crystal
structure of an RNA-bound 11-subunit eukaryotic exosome
complex." Nature, 495,
70-75. doi: 10.1038/nature11870.
|
Crystal structure of an 11-subunit eukaryotic exosome
complex bound to RNA . SNAP output
|
|
4ig8
|
transferase-RNA |
X-ray (2.7 Å) |
Donovan J, Dufner M, Korennykh A |
(2013) "Structural
basis for cytosolic double-stranded RNA surveillance by
human oligoadenylate synthetase 1."
Proc.Natl.Acad.Sci.USA, 110,
1652-1657. doi: 10.1073/pnas.1218528110.
|
Structural basis for cytosolic double-stranded RNA
surveillance by human oas1 . SNAP output
|
|
4ii9
|
transferase-peptide-RNA |
X-ray (1.66 Å) |
Fonvielle M, Li de La Sierra-Gallay I, El-Sagheer AH,
Lecerf M, Patin D, Mellal D, Mayer C, Blanot D, Gale N,
Brown T, van Tilbeurgh H, Etheve-Quelquejeu M, Arthur
M |
(2013) "The
Structure of FemXWv in Complex with a Peptidyl-RNA
Conjugate: Mechanism of Aminoacyl Transfer from
Ala-tRNA(Ala) to Peptidoglycan Precursors."
Angew.Chem.Int.Ed.Engl., 52,
7278-7281. doi: 10.1002/anie.201301411.
|
Crystal structure of weissella viridescens femxvv
non-ribosomal amino acid transferase in complex with a
peptidyl-RNA conjugate . SNAP output
|
|
4ijs
|
RNA binding protein-RNA |
X-ray (3.2 Å) |
Li BB, Wang Q, Pan X, Fernandez de Castro I, Sun Y,
Guo Y, Tao X, Risco C, Sui SF, Lou ZY |
(2013) "Bunyamwera
virus possesses a distinct nucleocapsid protein to
facilitate genome encapsidation."
Proc.Natl.Acad.Sci.USA, 110,
9048-9053. doi: 10.1073/pnas.1222552110.
|
Crystal structure of nucleocapsid protein encoded by
the prototypic member of orthobunyavirus . SNAP output
|
|
4ill
|
hydrolase-RNA |
X-ray (2.484 Å) |
Shao Y, Li H |
(2013) "Recognition
and cleavage of a nonstructured CRISPR RNA by its
processing endoribonuclease Cas6."
Structure, 21, 385-393. doi:
10.1016/j.str.2013.01.010.
|
Recognition and cleavage of a non-structured crispr RNA
by its processing endoribonuclease cas6 . SNAP output
|
|
4ilm
|
hydrolase-RNA |
X-ray (3.068 Å) |
Shao Y, Li H |
(2013) "Recognition
and cleavage of a nonstructured CRISPR RNA by its
processing endoribonuclease Cas6."
Structure, 21, 385-393. doi:
10.1016/j.str.2013.01.010.
|
Crispr RNA processing endoribonuclease . SNAP output
|
|
4io9
|
ribosome-ribosome inhibitor |
X-ray (3.2 Å) |
Magee TV, Han S, McCurdy SP, Nguyen TT, Granskog K,
Marr ES, Maguire BA, Huband MD, Chen JM, Subashi TA,
Shanmugasundaram V |
(2013) "Novel
3-O-carbamoyl erythromycin A derivatives (carbamolides)
with activity against resistant staphylococcal and
streptococcal isolates."
Bioorg.Med.Chem.Lett., 23,
1727-1731. doi: 10.1016/j.bmcl.2013.01.067.
|
Crystal structure of compound 4d bound to large
ribosomal subunit (50s) from deinococcus radiodurans .
SNAP output
|
|
4ioa
|
ribosome-ribosome inhibitor |
X-ray (3.2 Å) |
Magee TV, Han S, McCurdy SP, Nguyen TT, Granskog K,
Marr ES, Maguire BA, Huband MD, Chen JM, Subashi TA,
Shanmugasundaram V |
(2013) "Novel
3-O-carbamoyl erythromycin A derivatives (carbamolides)
with activity against resistant staphylococcal and
streptococcal isolates."
Bioorg.Med.Chem.Lett., 23,
1727-1731. doi: 10.1016/j.bmcl.2013.01.067.
|
Crystal structure of compound 4e bound to large
ribosomal subunit (50s) from deinococcus radiodurans .
SNAP output
|
|
4ioc
|
ribosome-ribosome inhibitor |
X-ray (3.6 Å) |
Magee TV, Han S, McCurdy SP, Nguyen TT, Granskog K,
Marr ES, Maguire BA, Huband MD, Chen JM, Subashi TA,
Shanmugasundaram V |
(2013) "Novel
3-O-carbamoyl erythromycin A derivatives (carbamolides)
with activity against resistant staphylococcal and
streptococcal isolates."
Bioorg.Med.Chem.Lett., 23,
1727-1731. doi: 10.1016/j.bmcl.2013.01.067.
|
Crystal structure of compound 4f bound to large
ribosomal subunit (50s) from deinococcus radiodurans .
SNAP output
|
|
4iqx
|
transferase-DNA |
X-ray (2.5 Å) |
Agudo R, Ferrer-Orta C, Arias A, de la Higuera I,
Perales C, Perez-Luque R, Verdaguer N, Domingo E |
(2010) "A
multi-step process of viral adaptation to a mutagenic
nucleoside analogue by modulation of transition types
leads to extinction-escape." Plos Pathog.,
6, e1001072. doi: 10.1371/journal.ppat.1001072.
|
Mutant p44s p169s m296i of foot-and-mouth disease virus
RNA-dependent RNA polymerase . SNAP output
|
|
4j1g
|
viral protein-RNA |
X-ray (2.789 Å) |
Niu F, Shaw N, Wang YE, Jiao L, Ding W, Li X, Zhu P,
Upur H, Ouyang S, Cheng G, Liu ZJ |
(2013) "Structure
of the Leanyer orthobunyavirus nucleoprotein-RNA
complex reveals unique architecture for RNA
encapsidation." Proc.Natl.Acad.Sci.USA,
110, 9054-9059. doi: 10.1073/pnas.1300035110.
|
Leanyer orthobunyavirus nucleoprotein-ssrna complex .
SNAP output
|
|
4j39
|
RNA binding protein-RNA |
X-ray (1.7 Å) |
Katorcha E, Tamjar J, Popov AN, Malinina L |
"Procrustean bed of RNA silencing suppression." |
Crystal structure of p19 in complex with double-helical
19mer RNA p(cag)3c(cug)3 . SNAP output
|
|
4j5v
|
RNA binding protein-RNA |
X-ray (2.15 Å) |
Tamjar J, Katorcha E, Cabo A, Delgado S, Popov AN,
Malinina L |
"Structural insights into CNG-repetitive RNAs
associated with human Trinucleotide Repeat Expansion
Diseases (TREDs)." |
Crystal structure of p19 in complex with double-helical
RNA 19mer p(cag)3c(ccg)3 . SNAP output
|
|
4j7l
|
hydrolase-RNA |
X-ray (1.8 Å) |
Jiao X, Chang JH, Kilic T, Tong L, Kiledjian M |
(2013) "A
mammalian pre-mRNA 5' end capping quality control
mechanism and an unexpected link of capping to pre-mRNA
processing." Mol.Cell,
50, 104-115. doi: 10.1016/j.molcel.2013.02.017.
|
Crystal structure of mouse dxo in complex with product
RNA and two magnesium ions . SNAP output
|
|
4j7m
|
hydrolase-RNA |
X-ray (1.7 Å) |
Jiao X, Chang JH, Kilic T, Tong L, Kiledjian M |
(2013) "A
mammalian pre-mRNA 5' end capping quality control
mechanism and an unexpected link of capping to pre-mRNA
processing." Mol.Cell,
50, 104-115. doi: 10.1016/j.molcel.2013.02.017.
|
Crystal structure of mouse dxo in complex with
substrate mimic RNA and calcium ion . SNAP output
|
|
4jgn
|
RNA binding protein-RNA |
X-ray (1.86 Å) |
Katorcha E, Tamjar J, Popov AN, Malinina L |
"Procrustean bed of RNA silencing suppression." |
Crystal structure of RNA silencing suppressor p19 with
1nt-5'-overhanging double-helical RNA 20mer
puug(cug)5cu . SNAP
output
|
|
4ji0
|
ribosome |
X-ray (3.492 Å) |
Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF,
Blanchard SC, Jogl G, Dahlberg AE, Gregory ST |
(2013) "The
central role of protein S12 in organizing the structure
of the decoding site of the ribosome."
Rna, 19, 1791-1801. doi:
10.1261/rna.040030.113.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4ji1
|
ribosome-antibiotic |
X-ray (3.144 Å) |
Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF,
Blanchard SC, Jogl G, Dahlberg AE, Gregory ST |
(2013) "The
central role of protein S12 in organizing the structure
of the decoding site of the ribosome."
Rna, 19, 1791-1801. doi:
10.1261/rna.040030.113.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4ji2
|
ribosome |
X-ray (3.64 Å) |
Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF,
Blanchard SC, Jogl G, Dahlberg AE, Gregory ST |
(2013) "The
central role of protein S12 in organizing the structure
of the decoding site of the ribosome."
Rna, 19, 1791-1801. doi:
10.1261/rna.040030.113.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4ji3
|
ribosome |
X-ray (3.35 Å) |
Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF,
Blanchard SC, Jogl G, Dahlberg AE, Gregory ST |
(2013) "The
central role of protein S12 in organizing the structure
of the decoding site of the ribosome."
Rna, 19, 1791-1801. doi:
10.1261/rna.040030.113.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4ji4
|
ribosome-antibiotic |
X-ray (3.692 Å) |
Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF,
Blanchard SC, Jogl G, Dahlberg AE, Gregory ST |
(2013) "The
central role of protein S12 in organizing the structure
of the decoding site of the ribosome."
Rna, 19, 1791-1801. doi:
10.1261/rna.040030.113.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4ji5
|
ribosome-antibiotic |
X-ray (3.85 Å) |
Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF,
Blanchard SC, Jogl G, Dahlberg AE, Gregory ST |
(2013) "The
central role of protein S12 in organizing the structure
of the decoding site of the ribosome."
Rna, 19, 1791-1801. doi:
10.1261/rna.040030.113.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4ji6
|
ribosome |
X-ray (3.55 Å) |
Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF,
Blanchard SC, Jogl G, Dahlberg AE, Gregory ST |
(2013) "The
central role of protein S12 in organizing the structure
of the decoding site of the ribosome."
Rna, 19, 1791-1801. doi:
10.1261/rna.040030.113.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4ji7
|
ribosome |
X-ray (3.5 Å) |
Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF,
Blanchard SC, Jogl G, Dahlberg AE, Gregory ST |
(2013) "The
central role of protein S12 in organizing the structure
of the decoding site of the ribosome."
Rna, 19, 1791-1801. doi:
10.1261/rna.040030.113.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4ji8
|
ribosome-antibiotic |
X-ray (3.742 Å) |
Demirci H, Wang L, Murphy FV, Murphy EL, Carr JF,
Blanchard SC, Jogl G, Dahlberg AE, Gregory ST |
(2013) "The
central role of protein S12 in organizing the structure
of the decoding site of the ribosome."
Rna, 19, 1791-1801. doi:
10.1261/rna.040030.113.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4jk0
|
RNA binding protein-RNA |
X-ray (2.3 Å) |
Katorcha E, Tamjar J, Popov AN, Malinina L |
"Procrustean bed of RNA silencing suppression." |
Crystal structure of t89q-mutant of RNA silencing
suppressor p19 with 2nt-5'-overhanging double-helical
RNA 21mer puuug(cug)5cu . SNAP output
|
|
4jng
|
viral protein-RNA |
X-ray (2.12 Å) |
Dong HH, Li P, Bottcher B, Elliott RM, Dong CJ |
(2013) "Crystal
structure of Schmallenberg orthobunyavirus
nucleoprotein-RNA complex reveals a novel RNA
sequestration mechanism." Rna,
19, 1129-1136. doi: 10.1261/rna.039057.113.
|
Schmallenberg virus nucleoprotein-RNA complex .
SNAP output
|
|
4jnx
|
RNA binding protein-RNA |
X-ray (1.95 Å) |
Katorcha E, Tamjar J, Popov AN, Malinina L |
"Procrustean bed of RNA silencing suppression." |
Crystal structure of RNA silencing suppressor p19
complexed with double-helical RNA 20mer pg(cug)6c .
SNAP output
|
|
4jv5
|
ribosome |
X-ray (3.162 Å) |
Fernandez IS, Ng CL, Kelley AC, Wu G, Yu YT,
Ramakrishnan V |
(2013) "Unusual
base pairing during the decoding of a stop codon by the
ribosome." Nature, 500,
107-110. doi: 10.1038/nature12302.
|
Crystal structures of pseudouridinilated stop codons
with asls . SNAP
output
|
|
4jvh
|
RNA binding protein |
X-ray (3.501 Å) |
Teplova M, Hafner M, Teplov D, Essig K, Tuschl T,
Patel DJ |
(2013) "Structure-function
studies of STAR family Quaking proteins bound to their
in vivo RNA target sites." Genes Dev.,
27, 928-940. doi: 10.1101/gad.216531.113.
|
Structure of the star domain of quaking protein in
complex with RNA . SNAP
output
|
|
4jvy
|
RNA binding protein |
X-ray (2.853 Å) |
Teplova M, Hafner M, Teplov D, Essig K, Tuschl T,
Patel DJ |
(2013) "Structure-function
studies of STAR family Quaking proteins bound to their
in vivo RNA target sites." Genes Dev.,
27, 928-940. doi: 10.1101/gad.216531.113.
|
Structure of the star (signal transduction and
activation of RNA) domain of gld-1 bound to RNA .
SNAP output
|
|
4jxx
|
ligase-RNA |
X-ray (2.3 Å) |
Rodriguez-Hernandez A, Spears JL, Gaston KW, Limbach
PA, Gamper H, Hou YM, Kaiser R, Agris PF, Perona JJ |
(2013) "Structural
and Mechanistic Basis for Enhanced Translational
Efficiency by 2-Thiouridine at the tRNA Anticodon
Wobble Position." J.Mol.Biol.,
425, 3888-3906. doi: 10.1016/j.jmb.2013.05.018.
|
Crystal structure of e coli e. coli glutaminyl-trna
synthetase bound to trna(gln)(cug) and atp from novel
cryostabilization conditions . SNAP output
|
|
4jxz
|
ligase-RNA |
X-ray (2.4 Å) |
Rodriguez-Hernandez A, Spears JL, Gaston KW, Limbach
PA, Gamper H, Hou YM, Kaiser R, Agris PF, Perona JJ |
(2013) "Structural
and Mechanistic Basis for Enhanced Translational
Efficiency by 2-Thiouridine at the tRNA Anticodon
Wobble Position." J.Mol.Biol.,
425, 3888-3906. doi: 10.1016/j.jmb.2013.05.018.
|
Structure of e. coli glutaminyl-trna synthetase bound
to atp and a trna(gln) acceptor containing a uug
anticodon . SNAP
output
|
|
4jya
|
ribosome |
X-ray (3.098 Å) |
Fernandez IS, Ng CL, Kelley AC, Wu G, Yu YT,
Ramakrishnan V |
(2013) "Unusual
base pairing during the decoding of a stop codon by the
ribosome." Nature, 500,
107-110. doi: 10.1038/nature12302.
|
Crystal structures of pseudouridinilated stop codons
with asls . SNAP
output
|
|
4jyz
|
ligase-RNA |
X-ray (2.5 Å) |
Rodriguez-Hernandez A, Spears JL, Gaston KW, Limbach
PA, Gamper H, Hou YM, Kaiser R, Agris PF, Perona JJ |
(2013) "Structural
and Mechanistic Basis for Enhanced Translational
Efficiency by 2-Thiouridine at the tRNA Anticodon
Wobble Position." J.Mol.Biol.,
425, 3888-3906. doi: 10.1016/j.jmb.2013.05.018.
|
Crystal structure of e. coli glutaminyl-trna synthetase
bound to atp and native trna(gln) containing the
cmnm5s2u34 anticodon wobble base . SNAP output
|
|
4jzv
|
hydrolase-RNA |
X-ray (2.2 Å) |
Piton J, Larue V, Thillier Y, Dorleans A, Pellegrini
O, Li de la Sierra-Gallay I, Vasseur JJ, Debart F, Tisne
C, Condon C |
(2013) "Bacillus
subtilis RNA deprotection enzyme RppH recognizes
guanosine in the second position of its
substrates." Proc.Natl.Acad.Sci.USA,
110, 8858-8863. doi: 10.1073/pnas.1221510110.
|
Crystal structure of the bacillus subtilis
pyrophosphohydrolase bsrpph bound to a non-hydrolysable
triphosphorylated dinucleotide RNA (pcp-pgpg) - second
guanosine residue in guanosine binding pocket .
SNAP output
|
|
4k0k
|
ribosome |
X-ray (3.4 Å) |
Fernandez IS, Ng CL, Kelley AC, Wu G, Yu YT,
Ramakrishnan V |
(2013) "Unusual
base pairing during the decoding of a stop codon by the
ribosome." Nature, 500,
107-110. doi: 10.1038/nature12302.
|
Crystal structure of the thermus thermophilus 30s
ribosomal subunit complexed with a serine-asl and mrna
containing a stop codon . SNAP output
|
|
4k4s
|
transferase-RNA |
X-ray (2.4 Å) |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB |
(2013) "Structures
of coxsackievirus, rhinovirus, and poliovirus
polymerase elongation complexes solved by engineering
RNA mediated crystal contacts." Plos One,
8, e60272. doi: 10.1371/journal.pone.0060272.
|
Poliovirus polymerase elongation complex (r3_form) .
SNAP output
|
|
4k4t
|
transferase-RNA |
X-ray (2.75 Å) |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB |
(2013) "Structures
of coxsackievirus, rhinovirus, and poliovirus
polymerase elongation complexes solved by engineering
RNA mediated crystal contacts." Plos One,
8, e60272. doi: 10.1371/journal.pone.0060272.
|
Poliovirus polymerase elongation complex (r4_form) .
SNAP output
|
|
4k4u
|
transferase-RNA |
X-ray (2.85 Å) |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB |
(2013) "Structures
of coxsackievirus, rhinovirus, and poliovirus
polymerase elongation complexes solved by engineering
RNA mediated crystal contacts." Plos One,
8, e60272. doi: 10.1371/journal.pone.0060272.
|
Poliovirus polymerase elongation complex (r5_form) .
SNAP output
|
|
4k4v
|
transferase-RNA |
X-ray (2.63 Å) |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB |
(2013) "Structures
of coxsackievirus, rhinovirus, and poliovirus
polymerase elongation complexes solved by engineering
RNA mediated crystal contacts." Plos One,
8, e60272. doi: 10.1371/journal.pone.0060272.
|
Poliovirus polymerase elongation complex (r5+1_form) .
SNAP output
|
|
4k4w
|
transferase-RNA |
X-ray (2.69 Å) |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB |
(2013) "Structures
of coxsackievirus, rhinovirus, and poliovirus
polymerase elongation complexes solved by engineering
RNA mediated crystal contacts." Plos One,
8, e60272. doi: 10.1371/journal.pone.0060272.
|
Poliovirus polymerase elongation complex (r5+2_form) .
SNAP output
|
|
4k4x
|
transferase-RNA |
X-ray (2.37 Å) |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB |
(2013) "Structures
of coxsackievirus, rhinovirus, and poliovirus
polymerase elongation complexes solved by engineering
RNA mediated crystal contacts." Plos One,
8, e60272. doi: 10.1371/journal.pone.0060272.
|
Coxsackievirus b3 polymerase elongation complex
(r2_form), RNA . SNAP
output
|
|
4k4y
|
transferase-RNA |
X-ray (2.72 Å) |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB |
(2013) "Structures
of coxsackievirus, rhinovirus, and poliovirus
polymerase elongation complexes solved by engineering
RNA mediated crystal contacts." Plos One,
8, e60272. doi: 10.1371/journal.pone.0060272.
|
Coxsackievirus b3 polymerase elongation complex
(r2+1_form) . SNAP
output
|
|
4k4z
|
transferase-RNA |
X-ray (2.17 Å) |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB |
(2013) "Structures
of coxsackievirus, rhinovirus, and poliovirus
polymerase elongation complexes solved by engineering
RNA mediated crystal contacts." Plos One,
8, e60272. doi: 10.1371/journal.pone.0060272.
|
Coxsackievirus b3 polymerase elongation complex
(r2_mg_form) . SNAP
output
|
|
4k50
|
transferase-RNA |
X-ray (2.93 Å) |
Gong P, Kortus MG, Nix JC, Davis RE, Peersen OB |
(2013) "Structures
of coxsackievirus, rhinovirus, and poliovirus
polymerase elongation complexes solved by engineering
RNA mediated crystal contacts." Plos One,
8, e60272. doi: 10.1371/journal.pone.0060272.
|
Rhinovirus 16 polymerase elongation complex (r1_form) .
SNAP output
|
|
4khp
|
ribosome-antibiotic |
X-ray (3.1 Å) |
Tourigny DS, Fernandez IS, Kelley AC, Vakiti RR,
Chattopadhyay AK, Dorich S, Hanessian S, Ramakrishnan
V |
(2013) "Crystal
Structure of a Bioactive Pactamycin Analog Bound to the
30S Ribosomal Subunit." J.Mol.Biol.,
425, 3907-3910. doi: 10.1016/j.jmb.2013.05.004.
|
Structure of the thermus thermophilus 30s ribosomal
subunit in complex with de-6-msa-pactamycin . SNAP output
|
|
4kji
|
RNA binding protein-RNA |
X-ray (3.2 Å) |
Morris ER, Hall G, Li C, Heeb S, Kulkarni RV,
Lovelock L, Silistre H, Messina M, Camara M, Emsley J,
Williams P, Searle MS |
(2013) "Structural
Rearrangement in an RsmA/CsrA Ortholog of Pseudomonas
aeruginosa Creates a Dimeric RNA-Binding Protein,
RsmN." Structure, 21,
1659-1671. doi: 10.1016/j.str.2013.07.007.
|
Novel re-arrangement of an rsma-csra family protein to
create a structurally distinct new RNA-binding family
member . SNAP output
|
|
4knq
|
RNA binding protein-RNA |
X-ray (1.82 Å) |
Tamjar J, Katorcha E, Cabo A, Delgado S, Popov AN,
Malinina L |
"Structural insights into CNG-repetitive RNAs
associated with human Trinucleotide Repeat Expansion
Diseases (TREDs)." |
Crystal structure of 1nt-5'-overhanging double-helical
ccg-repetitive RNA 20mer complexed with rss p19 .
SNAP output
|
|
4kq0
|
RNA binding protein-RNA |
X-ray (2.1 Å) |
Tamjar J, Katorcha E, Cabo A, Delgado S, Popov AN,
Malinina L |
"Structural insights into CNG-repetitive RNAs
associated with human Trinucleotide Repeat Expansion
Diseases (TREDs)." |
Crystal structure of double-helical cgg-repetitive RNA
19mer complexed with rss p19 . SNAP output
|
|
4kr2
|
ligase-RNA |
X-ray (3.292 Å) |
Qin X, Hao Z, Tian Q, Zhang Z, Zhou C, Xie W |
(2014) "Cocrystal
Structures of Glycyl-tRNA Synthetase in Complex with
tRNA Suggest Multiple Conformational States in
Glycylation." J.Biol.Chem.,
289, 20359-20369. doi: 10.1074/jbc.M114.557249.
|
Glycyl-trna synthetase in complex with trna-gly .
SNAP output
|
|
4kr3
|
ligase-RNA |
X-ray (3.235 Å) |
Qin X, Hao Z, Tian Q, Zhang Z, Zhou C, Xie W |
(2014) "Cocrystal
Structures of Glycyl-tRNA Synthetase in Complex with
tRNA Suggest Multiple Conformational States in
Glycylation." J.Biol.Chem.,
289, 20359-20369. doi: 10.1074/jbc.M114.557249.
|
Glycyl-trna synthetase mutant e71g in complex with
trna-gly . SNAP
output
|
|
4kr6
|
transferase-RNA |
X-ray (2.85 Å) |
Neumann P, Lakomek K, Naumann PT, Erwin WM, Lauhon
CT, Ficner R |
(2014) "Crystal
structure of a 4-thiouridine synthetase-RNA complex
reveals specificity of tRNA U8 modification."
Nucleic Acids Res., 42,
6673-6685. doi: 10.1093/nar/gku249.
|
Crystal structure of a 4-thiouridine synthetase - RNA
complex . SNAP
output
|
|
4kr7
|
transferase-RNA |
X-ray (3.421 Å) |
Neumann P, Lakomek K, Naumann PT, Erwin WM, Lauhon
CT, Ficner R |
(2014) "Crystal
structure of a 4-thiouridine synthetase-RNA complex
reveals specificity of tRNA U8 modification."
Nucleic Acids Res., 42,
6673-6685. doi: 10.1093/nar/gku249.
|
Crystal structure of a 4-thiouridine synthetase - RNA
complex with bound atp . SNAP output
|
|
4kr9
|
transferase-RNA |
X-ray (3.5 Å) |
Neumann P, Lakomek K, Naumann PT, Erwin WM, Lauhon
CT, Ficner R |
(2014) "Crystal
structure of a 4-thiouridine synthetase-RNA complex
reveals specificity of tRNA U8 modification."
Nucleic Acids Res., 42,
6673-6685. doi: 10.1093/nar/gku249.
|
Crystal structure of a 4-thiouridine synthetase - RNA
complex at 3.5 angstrom resolution . SNAP output
|
|
4kre
|
transcription-RNA |
X-ray (1.754 Å) |
Faehnle CR, Elkayam E, Haase AD, Hannon GJ,
Joshua-Tor L |
(2013) "The
making of a slicer: activation of human
argonaute-1." Cell Rep,
3, 1901-1909. doi: 10.1016/j.celrep.2013.05.033.
|
Structure of human argonaute-1 bound to endogenous sf9
RNA . SNAP output
|
|
4krf
|
transcription-RNA |
X-ray (2.101 Å) |
Faehnle CR, Elkayam E, Haase AD, Hannon GJ,
Joshua-Tor L |
(2013) "The
making of a slicer: activation of human
argonaute-1." Cell Rep,
3, 1901-1909. doi: 10.1016/j.celrep.2013.05.033.
|
Structure of human argonaute-1 let-7 complex . SNAP output
|
|
4ktg
|
RNA binding protein-RNA |
X-ray (1.92 Å) |
Tamjar J, Katorcha E, Cabo A, Delgado S, Popov AN,
Malinina L |
"Structural insights into CNG-repetitive RNAs
associated with human Trinucleotide Repeat Expansion
Diseases (TREDs)." |
Crystal structure of double-helical ggc-repetitive RNA
19mer complexed with rss p19 . SNAP output
|
|
4kvb
|
ribosome |
X-ray (4.198 Å) |
Connetti JL, Murphy EL, Dahlberg AE, Gregory ST, Jogl
G |
"Structural robustness of the ribosome inferred from
the X-ray crystal structure of a 30S ribosomal subunit
lacking ribosomal protein S17." |
Thermus thermophilus hb27 30s ribosomal subunit lacking
ribosomal protein s17 . SNAP output
|
|
4kzd
|
immune system-RNA |
X-ray (2.186 Å) |
Huang H, Suslov NB, Li NS, Shelke SA, Evans ME,
Koldobskaya Y, Rice PA, Piccirilli JA |
(2014) "A
G-quadruplex-containing RNA activates fluorescence in a
GFP-like fluorophore." Nat.Chem.Biol.,
10, 686-691. doi: 10.1038/nchembio.1561.
|
Crystal structure of an RNA aptamer in complex with
fluorophore and fab . SNAP output
|
|
4kze
|
immune system-RNA |
X-ray (2.404 Å) |
Huang H, Suslov NB, Li NS, Shelke SA, Evans ME,
Koldobskaya Y, Rice PA, Piccirilli JA |
(2014) "A
G-quadruplex-containing RNA activates fluorescence in a
GFP-like fluorophore." Nat.Chem.Biol.,
10, 686-691. doi: 10.1038/nchembio.1561.
|
Crystal structure of an RNA aptamer in complex with fab
. SNAP output
|
|
4l47
|
ribosome |
X-ray (3.22 Å) |
Maehigashi T, Dunkle JA, Miles SJ, Dunham CM |
(2014) "Structural
insights into +1 frameshifting promoted by expanded or
modification-deficient anticodon stem loops."
Proc.Natl.Acad.Sci.USA, 111,
12740-12745. doi: 10.1073/pnas.1409436111.
|
Crystal structure of frameshift suppressor trna sufa6
bound to codon ccc-u on the ribosome . SNAP output
|
|
4l71
|
ribosome |
X-ray (3.9 Å) |
Maehigashi T, Dunkle JA, Miles SJ, Dunham CM |
(2014) "Structural
insights into +1 frameshifting promoted by expanded or
modification-deficient anticodon stem loops."
Proc.Natl.Acad.Sci.USA, 111,
12740-12745. doi: 10.1073/pnas.1409436111.
|
Crystal structure of frameshift suppressor trna sufa6
bound to codon ccc-a on the ribosome . SNAP output
|
|
4l8h
|
structural protein |
X-ray (2.4 Å) |
Rumnieks J, Tars K |
(2014) "Crystal
structure of the bacteriophage q beta coat protein in
complex with the RNA operator of the replicase
gene." J.Mol.Biol., 426,
1039-1049. doi: 10.1016/j.jmb.2013.08.025.
|
Bacteriophage qbeta coat protein in complex with RNA
operator hairpin . SNAP
output
|
|
4l8r
|
RNA-RNA binding protein-hydrolase |
X-ray (2.6 Å) |
Tan D, Marzluff WF, Dominski Z, Tong L |
(2013) "Structure
of Histone Mrna Stem-Loop, Human Stem-Loop Binding
Protein, and 3'Hexo Ternary Complex."
Science, 339, 318. doi:
10.1126/SCIENCE.1228705.
|
Structure of mrna stem-loop, human stem-loop binding
protein and 3'hexo ternary complex . SNAP output
|
|
4lck
|
ribosomal protein-RNA |
X-ray (3.2 Å) |
Zhang J, Ferre-D'Amare AR |
(2013) "Co-crystal
structure of a T-box riboswitch stem I domain in
complex with its cognate tRNA." Nature,
500, 363-366. doi: 10.1038/nature12440.
|
Co-crystal structure of a t-box riboswitch stem i
domain in complex with its cognate trna . SNAP output
|
|
4lel
|
ribosome |
X-ray (3.9 Å) |
Maehigashi T, Dunkle JA, Miles SJ, Dunham CM |
(2014) "Structural
insights into +1 frameshifting promoted by expanded or
modification-deficient anticodon stem loops."
Proc.Natl.Acad.Sci.USA, 111,
12740-12745. doi: 10.1073/pnas.1409436111.
|
Crystal structure of frameshift suppressor trna sufa6
bound to codon ccg-g on the ribosome . SNAP output
|
|
4lf4
|
ribosome |
X-ray (3.34 Å) |
Demirci H, Belardinelli R, Carr J, Murphy IV F, Jogl
G, Dahlberg AE, Gregory ST |
(2013) "Crystal Structure of 30S ribosomal subunit
from Thermus thermophilus." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4lf5
|
ribosome |
X-ray (3.753 Å) |
Demirci H, Belardinelli R, Carr J, Murphy IV F, Jogl
G, Dahlberg AE, Gregory ST |
(2013) "Crystal Structure of 30S ribosomal subunit
from Thermus thermophilus." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4lf6
|
ribosome |
X-ray (3.31 Å) |
Demirci H, Belardinelli R, Carr J, Murphy IV F, Jogl
G, Dahlberg AE, Gregory ST |
(2013) "Crystal Structure of 30S ribosomal subunit
from Thermus thermophilus." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4lf7
|
ribosome |
X-ray (3.15 Å) |
Demirci H, Belardinelli R, Carr J, Murphy IV F, Jogl
G, Dahlberg AE, Gregory ST |
(2013) "Crystal Structure of 30S ribosomal subunit
from Thermus thermophilus." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4lf8
|
ribosome |
X-ray (3.15 Å) |
Demirci H, Belardinelli R, Carr J, Murphy IV F, Jogl
G, Dahlberg AE, Gregory ST |
(2013) "Crystal Structure of 30S ribosomal subunit
from Thermus thermophilus." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4lf9
|
ribosome |
X-ray (3.28 Å) |
Demirci H, Belardinelli R, Carr J, Murphy IV F, Jogl
G, Dahlberg AE, Gregory ST |
(2013) "Crystal Structure of 30S ribosomal subunit
from Thermus thermophilus." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4lfa
|
ribosome |
X-ray (3.65 Å) |
Demirci H, Belardinelli R, Carr J, Murphy IV F, Jogl
G, Dahlberg AE, Gregory ST |
(2013) "Crystal Structure of 30S ribosomal subunit
from Thermus thermophilus." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4lfb
|
ribosome |
X-ray (3.009 Å) |
Demirci H, Belardinelli R, Carr J, Murphy IV F, Jogl
G, Dahlberg AE, Gregory ST |
(2013) "Crystal Structure of 30S ribosomal subunit
from Thermus thermophilus." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4lfc
|
ribosome |
X-ray (3.602 Å) |
Demirci H, Belardinelli R, Carr J, Murphy IV F, Jogl
G, Dahlberg AE, Gregory ST |
(2013) |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4lfz
|
ribosome |
X-ray (3.92 Å) |
Maehigashi T, Dunkle JA, Miles SJ, Dunham CM |
(2014) "Structural
insights into +1 frameshifting promoted by expanded or
modification-deficient anticodon stem loops."
Proc.Natl.Acad.Sci.USA, 111,
12740-12745. doi: 10.1073/pnas.1409436111.
|
Crystal structure of frameshift suppressor trna sufa6
bound to codon ccc-u in the absence of paromomycin .
SNAP output
|
|
4lg2
|
RNA binding protein-RNA |
X-ray (2.7 Å) |
Bale S, Julien JP, Bornholdt ZA, Krois AS, Wilson IA,
Saphire EO |
(2013) "Ebolavirus
VP35 coats the backbone of double-stranded RNA for
interferon antagonism." J.Virol.,
87, 10385-10388. doi: 10.1128/JVI.01452-13.
|
Crystal structure of reston ebola virus vp35 RNA
binding domain bound to 12-bp dsrna . SNAP output
|
|
4lgt
|
isomerase-RNA |
X-ray (1.3 Å) |
Czudnochowski N, Ashley GW, Santi DV, Alian A,
Finer-Moore J, Stroud RM |
(2014) "The
mechanism of pseudouridine synthases from a covalent
complex with RNA, and alternate specificity for U2605
versus U2604 between close homologs." Nucleic
Acids Res., 42, 2037-2048. doi:
10.1093/nar/gkt1050.
|
Crystal structure of the catalytic domain of rlub in
complex with a 21-nucleotide RNA substrate . SNAP output
|
|
4lj0
|
RNA binding protein |
X-ray (2.15 Å) |
Kuhlmann SI, Valkov E, Stewart M |
(2014) "Structural
basis for the molecular recognition of polyadenosine
RNA by Nab2 Zn fingers." Nucleic Acids
Res., 42, 672-680. doi: 10.1093/nar/gkt876.
|
Nab2 zn fingers complexed with polyadenosine . SNAP output
|
|
4lmz
|
RNA binding protein |
X-ray (2.78 Å) |
Bhatt H, Manickam Y, Bhavesh NS |
"sequence specific RNA recognition of ETR3 RRM 1-2
domains." |
Structural insight into RNA recognition by rrm1+2
domain of human etr-3 protein . SNAP output
|
|
4lnt
|
ribosome |
X-ray (2.94 Å) |
Maehigashi T, Dunkle JA, Miles SJ, Dunham CM |
(2014) "Structural
insights into +1 frameshifting promoted by expanded or
modification-deficient anticodon stem loops."
Proc.Natl.Acad.Sci.USA, 111,
12740-12745. doi: 10.1073/pnas.1409436111.
|
Crystal structure of trna proline (cgg) bound to codon
ccc-u on the ribosome . SNAP output
|
|
4lq3
|
viral protein-replication inhibitor-RNA |
X-ray (2.6 Å) |
Tarantino D, Pezzullo M, Mastrangelo E, Croci R,
Rohayem J, Robel I, Bolognesi M, Milani M |
(2014) "Naphthalene-sulfonate
inhibitors of human norovirus RNA-dependent
RNA-polymerase." Antiviral Res.,
102, 23-28. doi: 10.1016/j.antiviral.2013.11.016.
|
Crystal structure of human norovirus RNA-dependent
RNA-polymerase bound to the inhibitor ppnds . SNAP output
|
|
4lsk
|
ribosome |
X-ray (3.48 Å) |
Maehigashi T, Dunkle JA, Miles SJ, Dunham CM |
(2014) "Structural
insights into +1 frameshifting promoted by expanded or
modification-deficient anticodon stem loops."
Proc.Natl.Acad.Sci.USA, 111,
12740-12745. doi: 10.1073/pnas.1409436111.
|
Crystal structure of trna proline (cgg) bound to codon
ccg-g on the ribosome . SNAP output
|
|
4lt8
|
ribosome |
X-ray (3.14 Å) |
Maehigashi T, Dunkle JA, Miles SJ, Dunham CM |
(2014) "Structural
insights into +1 frameshifting promoted by expanded or
modification-deficient anticodon stem loops."
Proc.Natl.Acad.Sci.USA, 111,
12740-12745. doi: 10.1073/pnas.1409436111.
|
Crystal structure of trna proline (cgg) bound to codon
ccc-g on the ribosome . SNAP output
|
|
4m2z
|
hydrolase-RNA |
X-ray (2.85 Å) |
Court DL, Gan J, Liang YH, Shaw GX, Tropea JE,
Costantino N, Waugh DS, Ji X |
(2013) "RNase
III: Genetics and Function; Structure and
Mechanism." Annu. Rev. Genet.,
47, 405-431. doi: 10.1146/annurev-genet-110711-155618.
|
Crystal structure of rnase iii complexed with
double-stranded RNA and cmp (type ii cleavage) .
SNAP output
|
|
4m30
|
hydrolase-RNA |
X-ray (2.501 Å) |
Court DL, Gan J, Liang YH, Shaw GX, Tropea JE,
Costantino N, Waugh DS, Ji X |
(2013) "RNase
III: Genetics and Function; Structure and
Mechanism." Annu. Rev. Genet.,
47, 405-431. doi: 10.1146/annurev-genet-110711-155618.
|
Crystal structure of rnase iii complexed with
double-stranded RNA and amp (type ii cleavage) .
SNAP output
|
|
4m4o
|
hydrolase-RNA |
X-ray (2.0 Å) |
Malashkevich VN, Padlan FC, Toro R, Girvin M, Almo
SC |
"Crystal structure of the aptamer minE-lysozyme
complex." |
Crystal structure of the aptamer mine-lysozyme complex
. SNAP output
|
|
4m59
|
RNA binding protein-RNA |
X-ray (2.46 Å) |
Yin P, Li Q, Yan C, Liu Y, Liu J, Yu F, Wang Z, Long
J, He J, Wang HW, Wang J, Zhu JK, Shi Y, Yan N |
(2013) "Structural
basis for the modular recognition of single-stranded
RNA by PPR proteins." Nature,
504, 168-171. doi: 10.1038/nature12651.
|
Crystal structure of the pentatricopeptide repeat
protein ppr10 in complex with an 18-nt psaj RNA element
. SNAP output
|
|
4m6d
|
hydrolase-RNA |
X-ray (2.68 Å) |
Malashkevich VN, Padlan FC, Toro R, Girvin M, Almo
SC |
"Crystal structure of the aptamer minF-lysozyme
complex." |
Crystal structure of the aptamer minf-lysozyme complex.
. SNAP output
|
|
4m7a
|
RNA binding protein |
X-ray (2.781 Å) |
Zhou L, Hang J, Zhou Y, Wan R, Lu G, Yin P, Yan C,
Shi Y |
(2014) "Crystal
structures of the Lsm complex bound to the 3' end
sequence of U6 small nuclear RNA." Nature,
506, 116-120. doi: 10.1038/nature12803.
|
Crystal structure of lsm2-8 complex bound to the 3' end
sequence of u6 snrna . SNAP output
|
|
4m7d
|
RNA binding protein |
X-ray (2.595 Å) |
Zhou L, Hang J, Zhou Y, Wan R, Lu G, Yin P, Yan C,
Shi Y |
(2014) "Crystal
structures of the Lsm complex bound to the 3' end
sequence of U6 small nuclear RNA." Nature,
506, 116-120. doi: 10.1038/nature12803.
|
Crystal structure of lsm2-8 complex bound to the RNA
fragment cguuu . SNAP
output
|
|
4mdx
|
hydrolase-RNA |
X-ray (1.5 Å) |
Simanshu DK, Yamaguchi Y, Park JH, Inouye M, Patel
DJ |
(2013) "Structural
Basis of mRNA Recognition and Cleavage by Toxin MazF
and Its Regulation by Antitoxin MazE in Bacillus
subtilis." Mol.Cell, 52,
447-458. doi: 10.1016/j.molcel.2013.09.006.
|
Crystal structure of bacillus subtilis mazf in complex
with RNA . SNAP
output
|
|
4n0t
|
RNA binding protein-RNA |
X-ray (1.7 Å) |
Montemayor EJ, Curran EC, Liao HH, Andrews KL, Treba
CN, Butcher SE, Brow DA |
(2014) "Core
structure of the U6 small nuclear ribonucleoprotein at
1.7- angstrom resolution."
Nat.Struct.Mol.Biol., 21,
544-551. doi: 10.1038/nsmb.2832.
|
Core structure of the u6 small nuclear
ribonucleoprotein at 1.7 angstrom resolution . SNAP output
|
|
4n2q
|
splicing-RNA |
X-ray (2.8 Å) |
Ke J, Chen RZ, Ban T, Zhou XE, Gu X, Tan MH, Chen C,
Kang Y, Brunzelle JS, Zhu JK, Melcher K, Xu HE |
(2013) "Structural
basis for RNA recognition by a dimeric PPR-protein
complex." Nat.Struct.Mol.Biol.,
20, 1377-1382. doi: 10.1038/nsmb.2710.
|
Crystal structure of tha8 in complex with zm4 RNA .
SNAP output
|
|
4n2s
|
splicing-RNA |
X-ray (3.0 Å) |
Ke J, Chen RZ, Ban T, Zhou XE, Gu X, Tan MH, Chen C,
Kang Y, Brunzelle JS, Zhu JK, Melcher K, Xu HE |
(2013) "Structural
basis for RNA recognition by a dimeric PPR-protein
complex." Nat.Struct.Mol.Biol.,
20, 1377-1382. doi: 10.1038/nsmb.2710.
|
Crystal structure of tha8 in complex with zm1a-6 RNA .
SNAP output
|
|
4n48
|
transferase-RNA |
X-ray (2.704 Å) |
Smietanski M, Werner M, Purta E, Kaminska KH,
Stepinski J, Darzynkiewicz E, Nowotny M, Bujnicki JM |
(2014) "Structural
analysis of human 2'-O-ribose methyltransferases
involved in mRNA cap structure formation." Nat
Commun, 5, 3004. doi: 10.1038/ncomms4004.
|
Cap-specific mrna (nucleoside-2'-o-)-methyltransferase
1 protein in complex with capped RNA fragment .
SNAP output
|
|
4ngb
|
hydrolase-RNA |
X-ray (2.25 Å) |
Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN,
Patel DJ |
(2014) "A
Phosphate-Binding Pocket within the
Platform-PAZ-Connector Helix Cassette of Human
Dicer." Mol.Cell, 53,
606-616. doi: 10.1016/j.molcel.2014.01.003.
|
Structure of human dicer platform-paz-connector helix
cassette in complex with 12-mer sirna having uu-3' ends
(2.25 angstrom resolution) . SNAP output
|
|
4ngc
|
hydrolase-RNA |
X-ray (2.104 Å) |
Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN,
Patel DJ |
(2014) "A
Phosphate-Binding Pocket within the
Platform-PAZ-Connector Helix Cassette of Human
Dicer." Mol.Cell, 53,
606-616. doi: 10.1016/j.molcel.2014.01.003.
|
Structure of human dicer platform-paz-connector helix
cassette in complex with 12-mer sirna having ua-3' ends
(2.1 angstrom resolution) . SNAP output
|
|
4ngd
|
hydrolase-RNA |
X-ray (1.958 Å) |
Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN,
Patel DJ |
(2014) "A
Phosphate-Binding Pocket within the
Platform-PAZ-Connector Helix Cassette of Human
Dicer." Mol.Cell, 53,
606-616. doi: 10.1016/j.molcel.2014.01.003.
|
Structure of human dicer platform-paz-connector helix
cassette in complex with 12-mer sirna having 5'-p and
uu-3' ends (1.95 angstrom resolution) . SNAP output
|
|
4ngf
|
hydrolase-RNA |
X-ray (3.101 Å) |
Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN,
Patel DJ |
(2014) "A
Phosphate-Binding Pocket within the
Platform-PAZ-Connector Helix Cassette of Human
Dicer." Mol.Cell, 53,
606-616. doi: 10.1016/j.molcel.2014.01.003.
|
Structure of human dicer platform-paz-connector helix
cassette in complex with 17-mer sirna having 5'-p and
uu-3' ends (3.1 angstrom resolution) . SNAP output
|
|
4ngg
|
hydrolase-RNA |
X-ray (2.6 Å) |
Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN,
Patel DJ |
(2014) "A
Phosphate-Binding Pocket within the
Platform-PAZ-Connector Helix Cassette of Human
Dicer." Mol.Cell, 53,
606-616. doi: 10.1016/j.molcel.2014.01.003.
|
Structure of human dicer platform-paz-connector helix
cassette in complex with 13-mer sirna having 5'-a and
uu-3' ends (2.6 angstrom resolution) . SNAP output
|
|
4nh3
|
hydrolase-RNA |
X-ray (2.616 Å) |
Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN,
Patel DJ |
(2014) "A
Phosphate-Binding Pocket within the
Platform-PAZ-Connector Helix Cassette of Human
Dicer." Mol.Cell, 53,
606-616. doi: 10.1016/j.molcel.2014.01.003.
|
Structure of human dicer platform-paz-connector helix
cassette in complex with 13-mer sirna having 5'-pu and
uu-3' ends (2.6 angstrom resolution) . SNAP output
|
|
4nh5
|
hydrolase-RNA |
X-ray (2.55 Å) |
Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN,
Patel DJ |
(2014) "A
Phosphate-Binding Pocket within the
Platform-PAZ-Connector Helix Cassette of Human
Dicer." Mol.Cell, 53,
606-616. doi: 10.1016/j.molcel.2014.01.003.
|
Structure of human dicer platform-paz-connector helix
cassette in complex with 14-mer sirna having 5'-puu and
uu-3' ends (2.55 angstrom resolution) . SNAP output
|
|
4nh6
|
hydrolase-RNA |
X-ray (2.551 Å) |
Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN,
Patel DJ |
(2014) "A
Phosphate-Binding Pocket within the
Platform-PAZ-Connector Helix Cassette of Human
Dicer." Mol.Cell, 53,
606-616. doi: 10.1016/j.molcel.2014.01.003.
|
Structure of human dicer platform-paz-connector helix
cassette in complex with 15-mer sirna having 5'-puuu
and uu-3' ends (2.55 angstrom resolution) . SNAP output
|
|
4nha
|
hydrolase-RNA |
X-ray (3.401 Å) |
Tian Y, Simanshu DK, Ma JB, Park JE, Heo I, Kim VN,
Patel DJ |
(2014) "A
Phosphate-Binding Pocket within the
Platform-PAZ-Connector Helix Cassette of Human
Dicer." Mol.Cell, 53,
606-616. doi: 10.1016/j.molcel.2014.01.003.
|
Structure of human dicer platform-paz-connector helix
cassette in complex with 16-mer sirna having 5'-p and
uu-3' ends (3.4 angstrom resolution) . SNAP output
|
|
4nku
|
transferase-RNA |
X-ray (1.94 Å) |
Munoz-Tello P, Gabus C, Thore S |
(2014) "A
critical switch in the enzymatic properties of the Cid1
protein deciphered from its product-bound crystal
structure." Nucleic Acids Res.,
42, 3372-3380. doi: 10.1093/nar/gkt1278.
|
Structure of cid1 in complex with its short product apu
. SNAP output
|
|
4nl3
|
RNA binding protein-RNA |
X-ray (3.1 Å) |
Kovach AR, Hoff KE, Canty JT, Orans J, Brennan
RG |
(2014) "Recognition
of U-rich RNA by Hfq from the Gram-positive pathogen
Listeria monocytogenes." Rna,
20, 1548-1559. doi: 10.1261/rna.044032.113.
|
Crystal structure of listeria monocytogenes hfq in
complex with u6 RNA . SNAP output
|
|
4nxm
|
ribosome |
X-ray (3.65 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the 30s ribosomal subunit from a
gidb (rsmg) mutant of thermus thermophilus (hb8) .
SNAP output
|
|
4nxn
|
ribosome-antibiotic |
X-ray (3.544 Å) |
Demirci H, Murphy IV F, Murphy E, Gregory ST,
Dahlberg AE, Jogl G |
"A structural basis for streptomycin
resistance." |
Crystal structure of the 30s ribosomal subunit from a
gidb (rsmg) mutant of thermus thermophilus (hb8), bound
with streptomycin . SNAP
output
|
|
4o26
|
RNA binding protein-RNA |
X-ray (3.001 Å) |
Huang J, Brown AF, Wu J, Xue J, Bley CJ, Rand DP, Wu
L, Zhang R, Chen JJ, Lei M |
(2014) "Structural
basis for protein-RNA recognition in telomerase."
Nat.Struct.Mol.Biol., 21,
507-512. doi: 10.1038/nsmb.2819.
|
Crystal structure of the trbd domain of tert and the
cr4-5 of tr . SNAP
output
|
|
4o8j
|
ligase-RNA |
X-ray (2.04 Å) |
Desai KK, Bingman CA, Cheng CL, Phillips Jr GN,
Raines RT |
(2014) "Structure
of RNA 3'-phosphate cyclase bound to substrate
RNA." Rna, 20, 1560-1566.
doi: 10.1261/rna.045823.114.
|
Crystal structure of rtca, the RNA 3'-terminal
phosphate cyclase from pyrococcus horikoshii, in
complex with racaaa3'phosphate and adenine. . SNAP output
|
|
4oau
|
hydrolase-RNA |
X-ray (2.6 Å) |
Han Y, Donovan J, Rath S, Whitney G, Chitrakar A,
Korennykh A |
(2014) "Structure
of human RNase L reveals the basis for regulated RNA
decay in the IFN response." Science,
343, 1244-1248. doi: 10.1126/science.1249845.
|
Complete human rnase l in complex with biological
activators. . SNAP
output
|
|
4oav
|
hydrolase-RNA |
X-ray (2.1 Å) |
Han Y, Donovan J, Rath S, Whitney G, Chitrakar A,
Korennykh A |
(2014) "Structure
of human RNase L reveals the basis for regulated RNA
decay in the IFN response." Science,
343, 1244-1248. doi: 10.1126/science.1249845.
|
Complete human rnase l in complex with 2-5a (5'-ppp
heptamer), amppcp and RNA substrate. . SNAP output
|
|
4oe1
|
RNA binding protein-RNA |
X-ray (2.8 Å) |
Li Q, Yan C, Xu H, Wang Z, Long J, Li W, Wu J, Yin P,
Yan N |
(2014) "Examination
of the dimerization states of the single-stranded RNA
recognition protein pentatricopeptide repeat 10
(PPR10)." J.Biol.Chem.,
289, 31503-31512. doi: 10.1074/jbc.M114.575472.
|
Crystal structure of the pentatricopeptide repeat
protein ppr10 (c256s-c430s-c449s) in complex with an
18-nt psaj RNA element . SNAP output
|
|
4ohy
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Dikfidan A, Loll B, Zeymer C, Magler I, Clausen T,
Meinhart A |
(2014) "RNA
specificity and regulation of catalysis in the
eukaryotic polynucleotide kinase clp1."
Mol.Cell, 54, 975-986. doi:
10.1016/j.molcel.2014.04.005.
|
C. elegans clp1 bound to ssrna dinucleotide gc,
amp-pnp, and mg2+(inhibited substrate bound state) .
SNAP output
|
|
4ohz
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Dikfidan A, Loll B, Zeymer C, Magler I, Clausen T,
Meinhart A |
(2014) "RNA
specificity and regulation of catalysis in the
eukaryotic polynucleotide kinase clp1."
Mol.Cell, 54, 975-986. doi:
10.1016/j.molcel.2014.04.005.
|
Bound to ssrna tetranucleotide gaaa, adp, and mg2+ .
SNAP output
|
|
4oi0
|
RNA binding protein-RNA |
X-ray (2.2 Å) |
Dikfidan A, Loll B, Zeymer C, Magler I, Clausen T,
Meinhart A |
(2014) "RNA
specificity and regulation of catalysis in the
eukaryotic polynucleotide kinase clp1."
Mol.Cell, 54, 975-986. doi:
10.1016/j.molcel.2014.04.005.
|
Bound to ssrna dinucleotide gc, adp, alf4-, and
mg2+(transition state, data set i) . SNAP output
|
|
4oi1
|
RNA binding protein-RNA |
X-ray (2.3 Å) |
Dikfidan A, Loll B, Zeymer C, Magler I, Clausen T,
Meinhart A |
(2014) "RNA
specificity and regulation of catalysis in the
eukaryotic polynucleotide kinase clp1."
Mol.Cell, 54, 975-986. doi:
10.1016/j.molcel.2014.04.005.
|
Clp1 bound to ssrna dinucleotide gc, adp, alf4-, and
mg2+(transition state, data set ii) . SNAP output
|
|
4ola
|
hydrolase-RNA |
X-ray (2.3 Å) |
Schirle NT, MacRae IJ |
(2012) "The
crystal structure of human Argonaute2."
Science, 336, 1037-1040. doi:
10.1126/science.1221551.
|
Crystal structure of human argonaute2 . SNAP output
|
|
4olb
|
hydrolase-RNA |
X-ray (2.899 Å) |
Schirle NT, MacRae IJ |
(2012) "The
crystal structure of human Argonaute2."
Science, 336, 1037-1040. doi:
10.1126/science.1221551.
|
Crystal structure of human argonaute2 bound to
tryptophan . SNAP
output
|
|
4oo1
|
hydrolase-RNA |
X-ray (3.3 Å) |
Wasmuth EV, Januszyk K, Lima CD |
(2014) "Structure
of an Rrp6-RNA exosome complex bound to poly(A)
RNA." Nature, 511,
435-439. doi: 10.1038/nature13406.
|
Structure of an rrp6-RNA exosome complex bound to
poly(a) RNA . SNAP
output
|
|
4oog
|
hydrolase-RNA |
X-ray (2.5 Å) |
Liang YH, Lavoie M, Comeau MA, Abou Elela S, Ji
X |
(2014) "Structure
of a Eukaryotic RNase III Postcleavage Complex Reveals
a Double-Ruler Mechanism for Substrate Selection."
Mol.Cell, 54, 431-444. doi:
10.1016/j.molcel.2014.03.006.
|
Crystal structure of yeast rnase iii (rnt1p) complexed
with the product of dsrna processing . SNAP output
|
|
4oq8
|
virus-RNA |
X-ray (1.45 Å) |
Larson SB, Day JS, McPherson A |
(2014) "Satellite
tobacco mosaic virus refined to 1.4 angstrom
resolution." Acta Crystallogr.,Sect.D,
70, 2316-2330. doi: 10.1107/S1399004714013789.
|
Satellite tobacco mosaic virus refined to 1.4 Å
resolution using icosahedral constraints . SNAP output
|
|
4ox9
|
ribosome-antibiotic |
X-ray (3.8 Å) |
Dunkle JA, Vinal K, Desai PM, Zelinskaya N, Savic M,
West DM, Conn GL, Dunham CM |
(2014) "Molecular
recognition and modification of the 30S ribosome by the
aminoglycoside-resistance methyltransferase NpmA."
Proc.Natl.Acad.Sci.USA, 111,
6275-6280. doi: 10.1073/pnas.1402789111.
|
Crystal structure of the aminoglycoside resistance
methyltransferase npma bound to the 30s ribosomal
subunit . SNAP
output
|
|
4p3e
|
RNA binding protein-RNA |
X-ray (3.5 Å) |
Grotwinkel JT, Wild K, Segnitz B, Sinning I |
(2014) "SRP RNA
remodeling by SRP68 explains its role in protein
translocation." Science,
344, 101-104. doi: 10.1126/science.1249094.
|
Structure of the human srp s domain . SNAP output
|
|
4p6f
|
ribosome-ribosome inhibitor |
X-ray (3.6 Å) |
Washington AZ, Benicewicz DB, Canzoneri JC, Fagan CE,
Mwakwari SC, Maehigashi T, Dunham CM, Oyelere AK |
(2014) "Macrolide-Peptide
Conjugates as Probes of the Path of Travel of the
Nascent Peptides through the Ribosome." Acs
Chem.Biol., 9, 2621-2631. doi:
10.1021/cb5003224.
|
Crystal structure of the peptolide 12c bound to
bacterial ribosome . SNAP output
|
|
4p70
|
ribosome |
X-ray (3.68 Å) |
Maehigashi T, Dunkle JA, Miles SJ, Dunham CM |
(2014) "Structural
insights into +1 frameshifting promoted by expanded or
modification-deficient anticodon stem loops."
Proc.Natl.Acad.Sci.USA, 111,
12740-12745. doi: 10.1073/pnas.1409436111.
|
Crystal structure of unmodified trna proline (cgg)
bound to codon ccg on the ribosome . SNAP output
|
|
4pdb
|
ribosomal protein-RNA |
X-ray (2.6 Å) |
Davlieva M, Donarski J, Wang J, Shamoo Y, Nikonowicz
EP |
(2014) "Structure
analysis of free and bound states of an RNA aptamer
against ribosomal protein S8 from Bacillus
anthracis." Nucleic Acids Res.,
42, 10795-10808. doi: 10.1093/nar/gku743.
|
Crystal structure of bacillus anthracis ribosomal
protein s8 in complex with an RNA aptamer . SNAP output
|
|
4pjo
|
splicing |
X-ray (3.3 Å) |
Kondo Y, Oubridge C, van Roon AM, Nagai K |
(2015) "Crystal
structure of human U1 snRNP, a small nuclear
ribonucleoprotein particle, reveals the mechanism of 5'
splice site recognition." Elife,
4. doi: 10.7554/eLife.04986.
|
Minimal u1 snrnp . SNAP
output
|
|
4pkd
|
gene regulation |
X-ray (2.5 Å) |
Kondo Y, Oubridge C, van Roon AM, Nagai K |
(2015) "Crystal
structure of human U1 snRNP, a small nuclear
ribonucleoprotein particle, reveals the mechanism of 5'
splice site recognition." Elife,
4. doi: 10.7554/eLife.04986.
|
U1-70k in complex with u1 snrna stem-loops 1 and u1-a
rrm in complex with stem-loop 2 . SNAP output
|
|
4pmi
|
RNA binding protein-RNA |
X-ray (3.2 Å) |
Jayaraman B, Crosby DC, Homer C, Ribeiro I, Mavor D,
Frankel AD |
(2014) "RNA-directed
remodeling of the HIV-1 protein Rev orchestrates
assembly of the Rev-Rev response element complex."
Elife, 4, e04120. doi:
10.7554/eLife.04120.
|
Crystal structure of rev and rev-response-element RNA
complex . SNAP
output
|
|
4pmw
|
hydrolase-RNA |
X-ray (2.95 Å) |
Faehnle CR, Walleshauser J, Joshua-Tor L |
(2014) "Mechanism
of Dis3l2 substrate recognition in the Lin28-let-7
pathway." Nature, 514,
252-256. doi: 10.1038/nature13553.
|
Structure of mouse dis3l2 in complex with oligou RNA
substrate . SNAP
output
|
|
4pr6
|
RNA binding protein-RNA |
X-ray (2.3 Å) |
Kapral GJ, Jain S, Noeske J, Doudna JA, Richardson
DC, Richardson JS |
(2014) "New
tools provide a second look at HDV ribozyme structure,
dynamics and cleavage." Nucleic Acids
Res., 42, 12833-12846. doi:
10.1093/nar/gku992.
|
A second look at the hdv ribozyme structure and
dynamics. . SNAP
output
|
|
4prf
|
RNA binding protein-RNA |
X-ray (2.395 Å) |
Kapral GJ, Jain S, Noeske J, Doudna JA, Richardson
DC, Richardson JS |
(2014) "New
tools provide a second look at HDV ribozyme structure,
dynamics and cleavage." Nucleic Acids
Res., 42, 12833-12846. doi:
10.1093/nar/gku992.
|
A second look at the hdv ribozyme structure and
dynamics. . SNAP
output
|
|
4q9q
|
RNA |
X-ray (2.45 Å) |
Huang H, Suslov NB, Li NS, Shelke SA, Evans ME,
Koldobskaya Y, Rice PA, Piccirilli JA |
(2014) "A
G-quadruplex-containing RNA activates fluorescence in a
GFP-like fluorophore." Nat.Chem.Biol.,
10, 686-691. doi: 10.1038/nchembio.1561.
|
Crystal structure of an RNA aptamer bound to
bromo-ligand analog in complex with fab . SNAP output
|
|
4q9r
|
RNA-immune system |
X-ray (3.12 Å) |
Huang H, Suslov NB, Li NS, Shelke SA, Evans ME,
Koldobskaya Y, Rice PA, Piccirilli JA |
(2014) "A
G-quadruplex-containing RNA activates fluorescence in a
GFP-like fluorophore." Nat.Chem.Biol.,
10, 686-691. doi: 10.1038/nchembio.1561.
|
Crystal structure of an RNA aptamer bound to
trifluoroethyl-ligand analog in complex with fab .
SNAP output
|
|
4qei
|
ligase-RNA |
X-ray (2.875 Å) |
Deng X, Qin X, Chen L, Jia Q, Zhang Y, Zhang Z, Lei
D, Ren G, Zhou Z, Wang Z, Li Q, Xie W |
(2016) "Large
Conformational Changes of Insertion 3 in Human
Glycyl-tRNA Synthetase (hGlyRS) during Catalysis."
J.Biol.Chem., 291, 5740-5752.
doi: 10.1074/jbc.M115.679126.
|
Two distinct conformational states of glyrs captured in
crystal lattice . SNAP
output
|
|
4qg3
|
ribosomal protein-RNA |
X-ray (2.0 Å) |
Tishchenko S, Kostareva O, Gabdulkhakov A, Mikhaylina
A, Nikonova E, Nevskaya N, Sarskikh A, Piendl W, Garber
M, Nikonov S |
(2015) "Protein-RNA
affinity of ribosomal protein L1 mutants does not
correlate with the number of intermolecular
interactions." Acta Crystallogr.,Sect.D,
71, 376-386. doi: 10.1107/S1399004714026248.
|
Crystal structure of mutant ribosomal protein g219v
tthl1 in complex with 80nt 23s RNA from thermus
thermophilus . SNAP
output
|
|
4qi2
|
RNA binding protein-RNA |
X-ray (3.0 Å) |
Schlundt A, Heinz GA, Janowski R, Geerlof A, Stehle
R, Heissmeyer V, Niessing D, Sattler M |
(2014) "Structural
basis for RNA recognition in roquin-mediated
post-transcriptional gene regulation."
Nat.Struct.Mol.Biol., 21,
671-678. doi: 10.1038/nsmb.2855.
|
X-ray structure of the roq domain from murine roquin-1
in complex with a 23-mer tnf-cde RNA . SNAP output
|
|
4qik
|
RNA binding protein-RNA |
X-ray (1.9 Å) |
Tan D, Zhou M, Kiledjian M, Tong L |
(2014) "The ROQ
domain of Roquin recognizes mRNA constitutive-decay
element and double-stranded RNA."
Nat.Struct.Mol.Biol., 21,
679-685. doi: 10.1038/nsmb.2857.
|
Crystal structure of the roq domain of human roquin in
complex with the tnf23 RNA duplex . SNAP output
|
|
4qil
|
RNA binding protein-RNA |
X-ray (2.9 Å) |
Tan D, Zhou M, Kiledjian M, Tong L |
(2014) "The ROQ
domain of Roquin recognizes mRNA constitutive-decay
element and double-stranded RNA."
Nat.Struct.Mol.Biol., 21,
679-685. doi: 10.1038/nsmb.2857.
|
Crystal structure of the roq domain of human roquin in
complex with the hmg19 stem-loop RNA . SNAP output
|
|
4qm6
|
transferase-RNA |
X-ray (1.5 Å) |
Das U, Wang LK, Smith P, Munir A, Shuman S |
(2014) "Structures
of bacterial polynucleotide kinase in a michaelis
complex with nucleoside triphosphate (NTP)-Mg2+ and
5'-OH RNA and a mixed substrate-product complex with
NTP-Mg2+ and a 5'-phosphorylated oligonucleotide."
J.Bacteriol., 196, 4285-4292.
doi: 10.1128/JB.02197-14.
|
Structure of bacterial polynucleotide kinase bound to
gtp and RNA . SNAP
output
|
|
4qoz
|
RNA-hydrolase-RNA binding protein |
X-ray (2.304 Å) |
Zhang J, Tan D, DeRose EF, Perera L, Dominski Z,
Marzluff WF, Tong L, Hall TM |
(2014) "Molecular
mechanisms for the regulation of histone mRNA
stem-loop-binding protein by phosphorylation."
Proc.Natl.Acad.Sci.USA, 111,
E2937-E2946. doi: 10.1073/pnas.1406381111.
|
Crystal structure of the histone mrna stem-loop,
stem-loop binding protein (phosphorylated), and 3'hexo
ternary complex . SNAP
output
|
|
4qpx
|
hydrolase-RNA |
X-ray (1.86 Å) |
Zamyatkin D, Rao C, Hoffarth E, Jurca G, Rho H, Parra
F, Grochulski P, Ng KK |
(2014) "Structure
of a backtracked state reveals conformational changes
similar to the state following nucleotide incorporation
in human norovirus polymerase." Acta
Crystallogr.,Sect.D, 70,
3099-3109. doi: 10.1107/S1399004714021518.
|
Nv polymerase post-incorporation-like complex .
SNAP output
|
|
4qqb
|
tranlation-RNA |
X-ray (2.8 Å) |
Hennig J, Militti C, Popowicz GM, Wang I, Sonntag M,
Geerlof A, Gabel F, Gebauer F, Sattler M |
(2014) "Structural
basis for the assembly of the Sxl-Unr translation
regulatory complex." Nature,
515, 287-290. doi: 10.1038/nature13693.
|
Structural basis for the assembly of the sxl-unr
translation regulatory complex . SNAP output
|
|
4qu6
|
RNA binding protein-RNA |
X-ray (1.75 Å) |
Joint Center for Structural Genomics (JCSG),
Partnership for T-Cell Biology (TCELL) |
"Crystal structure of a G-rich RNA sequence binding
factor 1 (GRSF1) from Homo sapiens at 1.75 A
resolution." |
Crystal structure of a g-rich RNA sequence binding
factor 1 (grsf1) from homo sapiens at 1.75 Å resolution
. SNAP output
|
|
4qu7
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Joint Center for Structural Genomics (JCSG),
Partnership for T-Cell Biology (TCELL) |
"Crystal structure of a G-rich RNA sequence binding
factor 1 (GRSF1) from Homo sapiens at 2.50 A
resolution." |
Crystal structure of a g-rich RNA sequence binding
factor 1 (grsf1) from homo sapiens at 2.50 Å resolution
. SNAP output
|
|
4qvc
|
RNA binding protein-RNA |
X-ray (1.99 Å) |
Wang LJ, Wang WW, Li FD, Zhang J, Wu JH, Gong QG, Shi
YY |
(2015) "Structural
insights into the recognition of the internal A-rich
linker from OxyS sRNA by Escherichia coli Hfq."
Nucleic Acids Res., 43,
2400-2411. doi: 10.1093/nar/gkv072.
|
E.coli hfq in complex with RNA aus . SNAP output
|
|
4qvd
|
RNA binding protein-RNA |
X-ray (1.972 Å) |
Wang LJ, Wang WW, Li FD, Zhang J, Wu JH, Gong QG, Shi
YY |
(2015) "Structural
insights into the recognition of the internal A-rich
linker from OxyS sRNA by Escherichia coli Hfq."
Nucleic Acids Res., 43,
2400-2411. doi: 10.1093/nar/gkv072.
|
E.coli hfq in complex with RNA ads . SNAP output
|
|
4qvi
|
ribosomal protein-RNA |
X-ray (1.9 Å) |
Tishchenko S, Kostareva O, Gabdulkhakov A, Mikhaylina
A, Nikonova E, Nevskaya N, Sarskikh A, Piendl W, Garber
M, Nikonov S |
(2015) "Protein-RNA
affinity of ribosomal protein L1 mutants does not
correlate with the number of intermolecular
interactions." Acta Crystallogr.,Sect.D,
71, 376-386. doi: 10.1107/S1399004714026248.
|
Crystal structure of mutant ribosomal protein m218l
tthl1 in complex with 80nt 23s RNA from thermus
thermophilus . SNAP
output
|
|
4r3i
|
RNA binding protein-RNA |
X-ray (1.8 Å) |
Xu C, Wang X, Liu K, Roundtree IA, Tempel W, Li Y, Lu
Z, He C, Min J |
(2014) "Structural
basis for selective binding of m(6)A RNA by the YTHDC1
YTH domain." Nat.Chem.Biol.,
10, 927-929. doi: 10.1038/nchembio.1654.
|
The crystal structure of an RNA complex . SNAP output
|
|
4r8i
|
cytokine-RNA |
X-ray (2.05 Å) |
Oberthur D, Achenbach J, Gabdulkhakov A, Buchner K,
Maasch C, Falke S, Rehders D, Klussmann S, Betzel C |
(2015) "Crystal
structure of a mirror-image L-RNA aptamer (Spiegelmer)
in complex with the natural L-protein target CCL2."
Nat Commun, 6, 6923. doi:
10.1038/ncomms7923.
|
High resolution structure of a mirror-image RNA
oligonucleotide aptamer in complex with the chemokine
ccl2 . SNAP output
|
|
4rcj
|
RNA binding protein-RNA |
X-ray (1.6 Å) |
Xu C, Liu K, Ahmed H, Loppnau P, Schapira M, Min
J |
(2015) "Structural
Basis for the Discriminative Recognition of
N6-Methyladenosine RNA by the Human YT521-B Homology
Domain Family of Proteins." J.Biol.Chem.,
290, 24902-24913. doi: 10.1074/jbc.M115.680389.
|
Crystal structure of ythdf1 yth domain in complex with
5mer m6a RNA . SNAP
output
|
|
4rcm
|
RNA binding protein-RNA |
X-ray (1.8 Å) |
Xu C, Liu K, Ahmed H, Loppnau P, Schapira M, Min
J |
(2015) "Structural
Basis for the Discriminative Recognition of
N6-Methyladenosine RNA by the Human YT521-B Homology
Domain Family of Proteins." J.Biol.Chem.,
290, 24902-24913. doi: 10.1074/jbc.M115.680389.
|
Crystal structure of the pho92 yth domain in complex
with m6a . SNAP
output
|
|
4rdx
|
ligase-RNA |
X-ray (2.55 Å) |
Tian Q, Wang C, Liu Y, Xie W |
(2015) "Structural
basis for recognition of G-1-containing tRNA by
histidyl-tRNA synthetase." Nucleic Acids
Res., 43, 2980-2990. doi:
10.1093/nar/gkv129.
|
Structure of histidinyl-trna synthetase in complex with
trna(his) . SNAP
output
|
|
4rmo
|
toxin-RNA |
X-ray (2.2 Å) |
Rao F, Short FL, Voss JE, Blower TR, Orme AL,
Whittaker TE, Luisi BF, Salmond GP |
(2015) "Co-evolution
of quaternary organization and novel RNA tertiary
interactions revealed in the crystal structure of a
bacterial protein-RNA toxin-antitoxin system."
Nucleic Acids Res., 43,
9529-9540. doi: 10.1093/nar/gkv868.
|
Crystal structure of the cptin type iii toxin-antitoxin
system from eubacterium rectale . SNAP output
|
|
4rqe
|
ligase-RNA |
X-ray (4.0 Å) |
Wang C, Guo Y, Tian Q, Jia Q, Gao Y, Zhang Q, Zhou C,
Xie W |
(2015) "SerRS-tRNASec
complex structures reveal mechanism of the first step
in selenocysteine biosynthesis." Nucleic Acids
Res., 43, 10534-10545. doi:
10.1093/nar/gkv996.
|
Human seryl-trna synthetase dimer complexed with two
molecules of trnasec . SNAP output
|
|
4rqf
|
ligase-RNA |
X-ray (3.503 Å) |
Wang C, Guo Y, Tian Q, Jia Q, Gao Y, Zhang Q, Zhou C,
Xie W |
(2015) "SerRS-tRNASec
complex structures reveal mechanism of the first step
in selenocysteine biosynthesis." Nucleic Acids
Res., 43, 10534-10545. doi:
10.1093/nar/gkv996.
|
Human seryl-trna synthetase dimer complexed with one
molecule of trnasec . SNAP output
|
|
4rwn
|
transferase-RNA |
X-ray (2.0 Å) |
Lohofener J, Steinke N, Kay-Fedorov P, Baruch P,
Nikulin A, Tishchenko S, Manstein DJ, Fedorov R |
(2015) "The
Activation Mechanism of 2'-5'-Oligoadenylate Synthetase
Gives New Insights Into OAS/cGAS Triggers of Innate
Immunity." Structure, 23,
851-862. doi: 10.1016/j.str.2015.03.012.
|
Crystal structure of the pre-reactive state of porcine
oas1 . SNAP output
|
|
4rwo
|
transferase-RNA |
X-ray (2.2 Å) |
Lohofener J, Steinke N, Kay-Fedorov P, Baruch P,
Nikulin A, Tishchenko S, Manstein DJ, Fedorov R |
(2015) "The
Activation Mechanism of 2'-5'-Oligoadenylate Synthetase
Gives New Insights Into OAS/cGAS Triggers of Innate
Immunity." Structure, 23,
851-862. doi: 10.1016/j.str.2015.03.012.
|
Crystal structure of the porcine oas1 l149r mutant in
complex with dsrna and apcpp in the amp donor position
. SNAP output
|
|
4rwp
|
transferase-RNA |
X-ray (2.25 Å) |
Lohofener J, Steinke N, Kay-Fedorov P, Baruch P,
Nikulin A, Tishchenko S, Manstein DJ, Fedorov R |
(2015) "The
Activation Mechanism of 2'-5'-Oligoadenylate Synthetase
Gives New Insights Into OAS/cGAS Triggers of Innate
Immunity." Structure, 23,
851-862. doi: 10.1016/j.str.2015.03.012.
|
Crystal structure of porcine oas1 in complex with dsrna
. SNAP output
|
|
4s2x
|
hydrolase-RNA |
X-ray (1.5 Å) |
Vasilyev N, Serganov A |
(2015) "Structures
of RNA Complexes with the Escherichia coli RNA
Pyrophosphohydrolase RppH Unveil the Basis for Specific
5'-End-dependent mRNA Decay."
J.Biol.Chem., 290, 9487-9499.
doi: 10.1074/jbc.M114.634824.
|
Structure of e. coli rpph bound to RNA and two
magnesium ions . SNAP
output
|
|
4s2y
|
hydrolase-RNA |
X-ray (1.6 Å) |
Vasilyev N, Serganov A |
(2015) "Structures
of RNA Complexes with the Escherichia coli RNA
Pyrophosphohydrolase RppH Unveil the Basis for Specific
5'-End-dependent mRNA Decay."
J.Biol.Chem., 290, 9487-9499.
doi: 10.1074/jbc.M114.634824.
|
Structure of e. coli rpph bound to RNA and three
magnesium ions . SNAP
output
|
|
4s3n
|
transferase-RNA |
X-ray (2.0 Å) |
Donovan J, Whitney G, Rath S, Korennykh A |
(2015) "Structural
mechanism of sensing long dsRNA via a noncatalytic
domain in human oligoadenylate synthetase 3."
Proc.Natl.Acad.Sci.USA, 112,
3949-3954. doi: 10.1073/pnas.1419409112.
|
Crystal structure of human oas3 domain i in complex
with dsrna . SNAP
output
|
|
4tu0
|
viral protein |
X-ray (2.3 Å) |
Morin B, Ferron FP, Malet H, Coutard B, Canard B |
"CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO
DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE
TRIMER." |
Crystal structure of chikungunya virus nsp3 macro
domain in complex with a 2'-5' oligoadenylate trimer .
SNAP output
|
|
4tua
|
ribosome |
X-ray (3.6 Å) |
Fagan CE, Maehigashi T, Dunkle JA, Miles SJ, Dunham
CM |
(2014) "Structural
insights into translational recoding by frameshift
suppressor tRNASufJ." Rna,
20, 1944-1954. doi: 10.1261/rna.046953.114.
|
Crystal structure of asl-thr bound to codon acc-a on
the ribosome . SNAP
output
|
|
4tub
|
ribosome |
X-ray (3.6 Å) |
Fagan CE, Maehigashi T, Dunkle JA, Miles SJ, Dunham
CM |
(2014) "Structural
insights into translational recoding by frameshift
suppressor tRNASufJ." Rna,
20, 1944-1954. doi: 10.1261/rna.046953.114.
|
Crystal structure of trna-thr bound to codon acc-c on
the ribosome . SNAP
output
|
|
4tuc
|
ribosome |
X-ray (3.6 Å) |
Fagan CE, Maehigashi T, Dunkle JA, Miles SJ, Dunham
CM |
(2014) "Structural
insights into translational recoding by frameshift
suppressor tRNASufJ." Rna,
20, 1944-1954. doi: 10.1261/rna.046953.114.
|
Crystal structure of asl-sufj bound to codon acc-a on
the ribosome . SNAP
output
|
|
4tud
|
ribosome |
X-ray (3.6 Å) |
Fagan CE, Maehigashi T, Dunkle JA, Miles SJ, Dunham
CM |
(2014) "Structural
insights into translational recoding by frameshift
suppressor tRNASufJ." Rna,
20, 1944-1954. doi: 10.1261/rna.046953.114.
|
Crystal structure of asl-sufj bound to codon acc-c on
the ribosome . SNAP
output
|
|
4tue
|
ribosome |
X-ray (3.5 Å) |
Fagan CE, Maehigashi T, Dunkle JA, Miles SJ, Dunham
CM |
(2014) "Structural
insights into translational recoding by frameshift
suppressor tRNASufJ." Rna,
20, 1944-1954. doi: 10.1261/rna.046953.114.
|
Crystal structure of asl-sufj bound to codon acc-u on
the ribosome . SNAP
output
|
|
4tuw
|
RNA binding protein-RNA |
X-ray (2.902 Å) |
Zhang J, Tan D, DeRose EF, Perera L, Dominski Z,
Marzluff WF, Tong L, Hall TM |
(2014) "Molecular
mechanisms for the regulation of histone mRNA
stem-loop-binding protein by phosphorylation."
Proc.Natl.Acad.Sci.USA, 111,
E2937-E2946. doi: 10.1073/pnas.1406381111.
|
Drosophila stem-loop binding protein complexed with
histone mrna stem-loop, phospho mimic of tpnk and
c-terminal region . SNAP
output
|
|
4tux
|
RNA binding protein-RNA |
X-ray (3.08 Å) |
Zhang J, Tan D, DeRose EF, Perera L, Dominski Z,
Marzluff WF, Tong L, Hall TM |
(2014) "Molecular
mechanisms for the regulation of histone mRNA
stem-loop-binding protein by phosphorylation."
Proc.Natl.Acad.Sci.USA, 111,
E2937-E2946. doi: 10.1073/pnas.1406381111.
|
Drosophila stem-loop binding protein complexed with
histone mrna stem-loop . SNAP output
|
|
4tv0
|
RNA binding protein-RNA |
X-ray (2.601 Å) |
Zhang J, Tan D, DeRose EF, Perera L, Dominski Z,
Marzluff WF, Tong L, Hall TM |
(2014) "Molecular
mechanisms for the regulation of histone mRNA
stem-loop-binding protein by phosphorylation."
Proc.Natl.Acad.Sci.USA, 111,
E2937-E2946. doi: 10.1073/pnas.1406381111.
|
Drosophila stem-loop binding protein complexed with
histone mrna stem-loop, selenomethionine derivative .
SNAP output
|
|
4tvx
|
hydrolase-RNA |
X-ray (3.24 Å) |
Jackson RN, Golden SM, van Erp PB, Carter J, Westra
ER, Brouns SJ, van der Oost J, Terwilliger TC, Read RJ,
Wiedenheft B |
(2014) "Structural
biology. Crystal structure of the CRISPR RNA-guided
surveillance complex from Escherichia coli."
Science, 345, 1473-1479. doi:
10.1126/science.1256328.
|
Crystal structure of the e. coli crispr RNA-guided
surveillance complex, cascade . SNAP output
|
|
4tyw
|
RNA binding protein-RNA |
X-ray (2.197 Å) |
Mallam AL, Sidote DJ, Lambowitz AM |
(2014) "Molecular
insights into RNA and DNA helicase evolution from the
determinants of specificity for a DEAD-box RNA
helicase." Elife, 3,
e04630. doi: 10.7554/eLife.04630.
|
Dead-box helicase mss116 bound to ssrna and adp-bef .
SNAP output
|
|
4tyy
|
RNA binding protein-RNA |
X-ray (2.74 Å) |
Mallam AL, Sidote DJ, Lambowitz AM |
(2014) "Molecular
insights into RNA and DNA helicase evolution from the
determinants of specificity for a DEAD-box RNA
helicase." Elife, 3,
e04630. doi: 10.7554/eLife.04630.
|
Dead-box helicase mss116 bound to ssrna and cdp-bef .
SNAP output
|
|
4tz0
|
RNA binding protein-RNA |
X-ray (2.35 Å) |
Mallam AL, Sidote DJ, Lambowitz AM |
(2014) "Molecular
insights into RNA and DNA helicase evolution from the
determinants of specificity for a DEAD-box RNA
helicase." Elife, 3,
e04630. doi: 10.7554/eLife.04630.
|
Dead-box helicase mss116 bound to ssrna and gdp-bef .
SNAP output
|
|
4tz6
|
RNA binding protein-RNA |
X-ray (3.209 Å) |
Mallam AL, Sidote DJ, Lambowitz AM |
(2014) "Molecular
insights into RNA and DNA helicase evolution from the
determinants of specificity for a DEAD-box RNA
helicase." Elife, 3,
e04630. doi: 10.7554/eLife.04630.
|
Dead-box helicase mss116 bound to ssrna and udp-bef .
SNAP output
|
|
4tzp
|
ribosomal protein-RNA |
X-ray (8.503 Å) |
Zhang J, Ferre-D'Amare AR |
(2014) "Dramatic
Improvement of Crystals of Large RNAs by Cation
Replacement and Dehydration." Structure,
22, 1363-1371. doi: 10.1016/j.str.2014.07.011.
|
As grown, untreated co-crystals of the ternary complex
containing a t-box stem i RNA, its cognate trnagly, and
b. subtilis ybxf protein . SNAP output
|
|
4tzv
|
ribosomal protein-RNA |
X-ray (5.03 Å) |
Zhang J, Ferre-D'Amare AR |
(2014) "Dramatic
Improvement of Crystals of Large RNAs by Cation
Replacement and Dehydration." Structure,
22, 1363-1371. doi: 10.1016/j.str.2014.07.011.
|
Co-crystals of the ternary complex containing a t-box
stem i RNA, its cognate trnagly, and b. subtilis ybxf
protein, treated by removing lithium sulfate post
crystallization . SNAP
output
|
|
4tzw
|
ribosomal protein-RNA |
X-ray (4.671 Å) |
Zhang J, Ferre-D'Amare AR |
(2014) "Dramatic
Improvement of Crystals of Large RNAs by Cation
Replacement and Dehydration." Structure,
22, 1363-1371. doi: 10.1016/j.str.2014.07.011.
|
Co-crystals of the ternary complex containing a t-box
stem i RNA, its cognate trnagly, and b. subtilis ybxf
protein, treated by removing lithium sulfate and
replacing mg2+ with sr2+ post crystallization .
SNAP output
|
|
4tzz
|
ribosomal protein-RNA |
X-ray (3.64 Å) |
Zhang J, Ferre-D'Amare AR |
(2014) "Dramatic
Improvement of Crystals of Large RNAs by Cation
Replacement and Dehydration." Structure,
22, 1363-1371. doi: 10.1016/j.str.2014.07.011.
|
Co-crystals of the ternary complex containing a t-box
stem i RNA, its cognate trnagly, and b. subtilis ybxf
protein, treated by removing lithium sulfate and
increasing peg3350 concentration from 20% to 45% post
crystallization . SNAP
output
|
|
4u1u
|
ribosome |
X-ray (2.95 Å) |
Noeske J, Huang J, Olivier NB, Giacobbe RA,
Zambrowski M, Cate JH |
(2014) "Synergy
of streptogramin antibiotics occurs independently of
their effects on translation."
Antimicrob.Agents Chemother.,
58, 5269-5279. doi: 10.1128/AAC.03389-14.
|
Crystal structure of the e. coli ribosome bound to
quinupristin. . SNAP
output
|
|
4u1v
|
ribosome |
X-ray (3.0 Å) |
Noeske J, Huang J, Olivier NB, Giacobbe RA,
Zambrowski M, Cate JH |
(2014) "Synergy
of streptogramin antibiotics occurs independently of
their effects on translation."
Antimicrob.Agents Chemother.,
58, 5269-5279. doi: 10.1128/AAC.03389-14.
|
Crystal structure of the e. coli ribosome bound to
linopristin. . SNAP
output
|
|
4u20
|
ribosome |
X-ray (2.9 Å) |
Noeske J, Huang J, Olivier NB, Giacobbe RA,
Zambrowski M, Cate JH |
(2014) "Synergy
of streptogramin antibiotics occurs independently of
their effects on translation."
Antimicrob.Agents Chemother.,
58, 5269-5279. doi: 10.1128/AAC.03389-14.
|
Crystal structure of the e. coli ribosome bound to
flopristin. . SNAP
output
|
|
4u24
|
ribosome |
X-ray (2.9 Å) |
Noeske J, Huang J, Olivier NB, Giacobbe RA,
Zambrowski M, Cate JH |
(2014) "Synergy
of streptogramin antibiotics occurs independently of
their effects on translation."
Antimicrob.Agents Chemother.,
58, 5269-5279. doi: 10.1128/AAC.03389-14.
|
Crystal structure of the e. coli ribosome bound to
dalfopristin. . SNAP
output
|
|
4u25
|
ribosome |
X-ray (2.9 Å) |
Noeske J, Huang J, Olivier NB, Giacobbe RA,
Zambrowski M, Cate JH |
(2014) "Synergy
of streptogramin antibiotics occurs independently of
their effects on translation."
Antimicrob.Agents Chemother.,
58, 5269-5279. doi: 10.1128/AAC.03389-14.
|
Crystal structure of the e. coli ribosome bound to
virginiamycin m1. . SNAP
output
|
|
4u26
|
ribosome |
X-ray (2.8 Å) |
Noeske J, Huang J, Olivier NB, Giacobbe RA,
Zambrowski M, Cate JH |
(2014) "Synergy
of streptogramin antibiotics occurs independently of
their effects on translation."
Antimicrob.Agents Chemother.,
58, 5269-5279. doi: 10.1128/AAC.03389-14.
|
Crystal structure of the e. coli ribosome bound to
dalfopristin and quinupristin. . SNAP output
|
|
4u27
|
ribosome |
X-ray (2.8 Å) |
Noeske J, Huang J, Olivier NB, Giacobbe RA,
Zambrowski M, Cate JH |
(2014) "Synergy
of streptogramin antibiotics occurs independently of
their effects on translation."
Antimicrob.Agents Chemother.,
58, 5269-5279. doi: 10.1128/AAC.03389-14.
|
Crystal structure of the e. coli ribosome bound to
flopristin and linopristin. . SNAP output
|
|
4u3m
|
ribosome |
X-ray (3.0 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of anisomycin bound to the yeast 80s
ribosome . SNAP
output
|
|
4u3n
|
ribosome |
X-ray (3.2 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of cca trinucleotide bound to the
yeast 80s ribosome . SNAP output
|
|
4u3u
|
ribosome |
X-ray (2.9 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of cycloheximide bound to the yeast
80s ribosome . SNAP
output
|
|
4u4n
|
ribosome |
X-ray (3.1 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of edeine bound to the yeast 80s
ribosome . SNAP
output
|
|
4u4o
|
ribosome |
X-ray (3.6 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of geneticin bound to the yeast 80s
ribosome . SNAP
output
|
|
4u4q
|
ribosome |
X-ray (3.0 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of homoharringtonine bound to the
yeast 80s ribosome . SNAP output
|
|
4u4r
|
ribosome |
X-ray (2.801 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of lactimidomycin bound to the yeast
80s ribosome . SNAP
output
|
|
4u4u
|
ribosome |
X-ray (3.0 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of lycorine bound to the yeast 80s
ribosome . SNAP
output
|
|
4u4y
|
ribosome |
X-ray (3.2 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of pactamycin bound to the yeast 80s
ribosome . SNAP
output
|
|
4u4z
|
ribosome |
X-ray (3.1 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of phyllanthoside bound to the yeast
80s ribosome . SNAP
output
|
|
4u50
|
ribosome |
X-ray (3.2 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of verrucarin bound to the yeast 80s
ribosome . SNAP
output
|
|
4u51
|
ribosome |
X-ray (3.2 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of narciclasine bound to the yeast
80s ribosome . SNAP
output
|
|
4u52
|
ribosome |
X-ray (3.0 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of nagilactone c bound to the yeast
80s ribosome . SNAP
output
|
|
4u53
|
ribosome |
X-ray (3.3 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of deoxynivalenol bound to the yeast
80s ribosome . SNAP
output
|
|
4u55
|
ribosome |
X-ray (3.2 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of cryptopleurine bound to the yeast
80s ribosome . SNAP
output
|
|
4u56
|
ribosome |
X-ray (3.45 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of blasticidin s bound to the yeast
80s ribosome . SNAP
output
|
|
4u67
|
ribosome |
X-ray (3.65 Å) |
Wekselman I, Zimmerman E, Davidovich C, Belousoff M,
Matzov D, Krupkin M, Rozenberg H, Bashan A, Friedlander
G, Kjeldgaard J, Ingmer H, Lindahl L, Zengel JM, Yonath
A |
(2017) "The
Ribosomal Protein uL22 Modulates the Shape of the
Protein Exit Tunnel." Structure,
25, 1233-1241.e3. doi: 10.1016/j.str.2017.06.004.
|
Crystal structure of the large ribosomal subunit (50s)
of deinococcus radiodurans containing a three residue
insertion in l22 . SNAP
output
|
|
4u6f
|
ribosome |
X-ray (3.1 Å) |
Garreau de Loubresse N, Prokhorova I, Holtkamp W,
Rodnina MV, Yusupova G, Yusupov M |
(2014) "Structural
basis for the inhibition of the eukaryotic
ribosome." Nature, 513,
517-522. doi: 10.1038/nature13737.
|
Crystal structure of t-2 toxin bound to the yeast 80s
ribosome . SNAP
output
|
|
4u7u
|
RNA binding protein-RNA |
X-ray (3.003 Å) |
Zhao H, Sheng G, Wang J, Wang M, Bunkoczi G, Gong W,
Wei Z, Wang Y |
(2014) "Crystal
structure of the RNA-guided immune surveillance Cascade
complex in Escherichia coli." Nature,
515, 147-150. doi: 10.1038/nature13733.
|
Crystal structure of RNA-guided immune cascade complex
from e.coli . SNAP
output
|
|
4u8t
|
RNA binding protein-RNA |
X-ray (2.7 Å) |
Luo S, Tong L |
(2014) "Molecular
basis for the recognition of methylated adenines in RNA
by the eukaryotic YTH domain."
Proc.Natl.Acad.Sci.USA, 111,
13834-13839. doi: 10.1073/pnas.1412742111.
|
Crystal structure of yth domain of zygosaccharomyces
rouxii mrb1 protein in complex with n6-methyladenosine
RNA . SNAP output
|
|
4udv
|
viral protein |
cryo-EM (3.35 Å) |
Fromm SA, Bharat TAM, Jakobi AJ, Hagen WJH, Sachse
C |
(2015) "Seeing
Tobacco Mosaic Virus Through Direct Electron
Detectors." J.Struct.Biol.,
189, 87. doi: 10.1016/J.JSB.2014.12.002.
|
cryo-EM structure of tmv at 3.35 Å resolution .
SNAP output
|
|
4ue4
|
translation |
cryo-EM (7.0 Å) |
Beckert B, Kedrov A, Sohmen D, Kempf G, Wild K,
Sinning I, Stahlberg H, Wilson DN, Beckmann R |
(2015) "Translational
Arrest by a Prokaryotic Signal Recognition Particle is
Mediated by RNA Interactions."
Nat.Struct.Mol.Biol., 22,
767. doi: 10.1038/NSMB.3086.
|
Structural basis for targeting and elongation arrest of
bacillus signal recognition particle . SNAP output
|
|
4ue5
|
translation |
cryo-EM (9.0 Å) |
Beckert B, Kedrov A, Sohmen D, Kempf G, Wild K,
Sinning I, Stahlberg H, Wilson DN, Beckmann R |
(2015) "Translational
Arrest by a Prokaryotic Signal Recognition Particle is
Mediated by RNA Interactions."
Nat.Struct.Mol.Biol., 22,
767. doi: 10.1038/NSMB.3086.
|
Structural basis for targeting and elongation arrest of
bacillus signal recognition particle . SNAP output
|
|
4uer
|
translation |
cryo-EM (6.47 Å) |
Aylett CHS, Boehringer D, Erzberger JP, Schaefer T,
Ban N |
(2015) "Structure
of a Yeast 40S-Eif1-Eif1A-Eif3-Eif3J Initiation
Complex." Nat.Struct.Mol.Biol.,
22, 269. doi: 10.1038/NSMB.2963.
|
40s-eif1-eif1a-eif3-eif3j translation initiation
complex from lachancea kluyveri . SNAP output
|
|
4uft
|
RNA binding protein |
cryo-EM (4.3 Å) |
Gutsche I, Desfosses A, Effantin G, Ling WL, Haupt M,
Ruigrok RWH, Sachse C, Schoehn G |
(2015) "Near-Atomic
Cryo-Em Structure of the Helical Measles Virus
Nucleocapsid." Science,
348, 704. doi: 10.1126/SCIENCE.AAA5137.
|
Structure of the helical measles virus nucleocapsid .
SNAP output
|
|
4ujc
|
ribosome |
cryo-EM (9.5 Å) |
Yamamoto H, Unbehaun A, Loerke J, Behrmann E, Collier
M, Burger J, Mielke T, Spahn CMT |
(2014) "Structure
of the Mammalian 80S Initiation Complex with Initiation
Factor 5B on Hcv-Ires RNA."
Nat.Struct.Mol.Biol., 21,
721. doi: 10.1038/NSMB.2859.
|
Mammalian 80s hcv-ires initiation complex with eif5b
post-like state . SNAP
output
|
|
4ujd
|
ribosome |
cryo-EM (8.9 Å) |
Yamamoto H, Unbehaun A, Loerke J, Behrmann E,
Marianne C, Burger J, Mielke T, Spahn CMT |
(2014) "Structure
of the Mammalian 80S Initiation Complex with Eif5B on
Hcv Ires." Nat.Struct.Mol.Biol.,
21, 721. doi: 10.1038/NSMB.2859.
|
Mammalian 80s hcv-ires initiation complex with eif5b
pre-like state . SNAP
output
|
|
4uje
|
ribosome |
cryo-EM (6.9 Å) |
Budkevich TV, Giesebrecht J, Behrmann E, Loerke J,
Ramrath DJ, Mielke T, Ismer J, Hildebrand PW, Tung CS,
Nierhaus KH, Sanbonmatsu KY, Spahn CM |
(2014) "Regulation
of the Mammalian Elongation Cycle by Subunit Rolling: A
Eukaryotic-Specific Ribosome Rearrangement."
Cell(Cambridge,Mass.), 158,
121. doi: 10.1016/J.CELL.2014.04.044.
|
Regulation of the mammalian elongation cycle by 40s
subunit rolling: a eukaryotic-specific ribosome
rearrangement . SNAP
output
|
|
4uy8
|
ribosome |
cryo-EM (3.8 Å) |
Bischoff L, Berninghausen O, Beckmann R |
(2014) "Molecular
Basis for the Ribosome Functioning as an L-Tryptophan
Sensor." Cell Rep., 9,
469. doi: 10.1016/J.CELREP.2014.09.011.
|
Molecular basis for the ribosome functioning as a
l-tryptophan sensor - cryo-EM structure of a tnac
stalled e.coli ribosome . SNAP output
|
|
4uyj
|
signaling protein |
X-ray (3.35 Å) |
Bousset L, Mary C, Brooks MA, Scherrer A, Strub K,
Cusack S |
(2014) "Crystal
Structure of a Signal Recognition Particle Alu Domain
in the Elongation Arrest Conformation."
RNA, 20, 1955. doi: 10.1261/RNA.047209.114.
|
Crystal structure of a signal recognition particle alu
domain in the elongation arrest conformation . SNAP output
|
|
4uyk
|
signaling protein |
X-ray (3.22 Å) |
Bousset L, Mary C, Brooks MA, Scherrer A, Strub K,
Cusack S |
(2014) "Crystal
Structure of a Signal Recognition Particle Alu Domain
in the Elongation Arrest Conformation."
RNA, 20, 1955. doi: 10.1261/RNA.047209.114.
|
Crystal structure of a signal recognition particle alu
domain in the elongation arrest conformation . SNAP output
|
|
4v19
|
ribosome |
cryo-EM (3.4 Å) |
Greber BJ, Boehringer D, Leibundgut M, Bieri P,
Leitner A, Schmitz N, Aebersold R, Ban N |
(2014) "The
Complete Structure of the Large Subunit of the
Mammalian Mitochondrial Ribosome." Nature,
515, 283. doi: 10.1038/NATURE13895.
|
Structure of the large subunit of the mammalian
mitoribosome, part 1 of 2 . SNAP output
|
|
4v2s
|
RNA binding protein-RNA |
X-ray (3.48 Å) |
Dimastrogiovanni D, Frohlich KS, Bandyra KJ, Bruce
HA, Hohensee S, Vogel J, Luisi BF |
(2014) "Recognition
of the small regulatory RNA RydC by the bacterial Hfq
protein." Elife, 3. doi:
10.7554/eLife.05375.
|
Crystal structure of hfq in complex with the srna rydc
. SNAP output
|
|
4v49
|
ribosome |
X-ray (8.7 Å) |
Vila-Sanjurjo A, Ridgeway WK, Seymaner V, Zhang W,
Santoso S, Yu K, Cate JHD |
(2003) "X-ray
Crystal Structures of the WT and a Hyper-Accurate
Ribosome From Escherichia Coli."
Proc.Natl.Acad.Sci.USA, 100,
8682-8687. doi: 10.1073/pnas.1133380100.
|
Crystal structure of a streptomycin dependent ribosome
from e. coli 70s ribosome. . SNAP output
|
|
4v4a
|
ribosome |
X-ray (9.5 Å) |
Vila-Sanjurjo A, Ridgeway WK, Seymaner V, Zhang W,
Santoso S, Yu K, Cate JHD |
(2003) "X-ray
crystal structures of the WT and a hyper-accurate
ribosome from Escherichia coli."
Proc.Natl.Acad.Sci.USA, 100,
8682-8687. doi: 10.1073/pnas.1133380100.
|
Crystal structure of the wild type ribosome from e.
coli 70s ribosome. . SNAP output
|
|
4v4f
|
RNA binding protein |
X-ray (1.9 Å) |
Hopcroft NH, Manfredo A, Wendt AL, Brzozowski AM,
Gollnick P, Antson AA |
(2004) "The
Interaction of RNA with Trap: The Role of Triplet
Repeats and Separating Spacer Nucleotides."
J.Mol.Biol., 338, 43. doi:
10.1016/J.JMB.2004.02.038.
|
The structure of the trp RNA-binding attenuation
protein (trap) bound to a RNA molecule containing uagau
repeats . SNAP
output
|
|
4v4g
|
ribosome |
X-ray (11.5 Å) |
Vila-Sanjurjo A, Schuwirth BS, Hau CW, Cate JH |
(2004) "Structural
basis for the control of translation initiation during
stress." Nat.Struct.Mol.Biol.,
11, 1054-1059. doi: 10.1038/nsmb850.
|
Crystal structure of five 70s ribosomes from
escherichia coli in complex with protein y. . SNAP output
|
|
4v4h
|
ribosome |
X-ray (3.46 Å) |
Schuwirth BS, Day JM, Hau CW, Janssen GR, Dahlberg
AE, Cate JHD, Vila-Sanjurjo A |
(2006) "Structural
analysis of kasugamycin inhibition of translation."
Nat.Struct.Mol.Biol., 13,
879-886. doi: 10.1038/nsmb1150.
|
Crystal structure of the bacterial ribosome from
escherichia coli in complex with the antibiotic
kasugamyin at 3.5a resolution. . SNAP output
|
|
4v4i
|
ribosome |
X-ray (3.71 Å) |
Korostelev A, Trakhanov S, Laurberg M, Noller HF |
(2006) "Crystal
Structure of a 70S Ribosome-tRNA Complex Reveals
Functional Interactions and Rearrangements."
Cell(Cambridge,Mass.), 126,
1065-1077. doi: 10.1016/j.cell.2006.08.032.
|
Crystal structure of a 70s ribosome-trna complex
reveals functional interactions and rearrangements. .
SNAP output
|
|
4v4j
|
ribosome |
X-ray (3.83 Å) |
Korostelev A, Trakhanov S, Asahara H, Laurberg M,
Lancaster L, Noller HF |
(2007) "Interactions
and dynamics of the Shine Dalgarno helix in the 70S
ribosome." Proc.Natl.Acad.Sci.Usa,
104, 16840-16843. doi: 10.1073/pnas.0707850104.
|
Interactions and dynamics of the shine-dalgarno helix
in the 70s ribosome. . SNAP output
|
|
4v4n
|
ribosome-protein transport |
cryo-EM (9.0 Å) |
Park E, Menetret JF, Gumbart JC, Ludtke SJ, Li W,
Whynot A, Rapoport TA, Akey CW |
(2013) "Structure
of the SecY channel during initiation of protein
translocation." Nature,
506, 102-106. doi: 10.1038/nature12720.
|
Structure of the methanococcus jannaschii
ribosome-secyebeta channel complex . SNAP output
|
|
4v4p
|
ribosome |
X-ray (5.5 Å) |
Jenner L, Romby P, Rees B, Schulze-Briese C, Springer
M, Ehresmann C, Ehresmann B, Moras D, Yusupova G, Yusupov
M |
(2005) "Translational
operator of mRNA on the ribosome: how repressor
proteins exclude ribosome binding."
Science, 308, 120-123. doi:
10.1126/science.1105639.
|
Crystal structure of 70s ribosome with thrs operator
and trnas. . SNAP
output
|
|
4v4q
|
ribosome |
X-ray (3.46 Å) |
Schuwirth BS, Borovinskaya MA, Hau CW, Zhang W,
Vila-Sanjurjo A, Holton JM, Cate JH |
(2005) "Structures
of the bacterial ribosome at 3.5 A resolution."
Science, 310, 827-834. doi:
10.1126/science.1117230.
|
Crystal structure of the bacterial ribosome from
escherichia coli at 3.5 Å resolution. . SNAP output
|
|
4v4v
|
ribosome |
cryo-EM (15.0 Å) |
Mitra K, Schaffitzel C, Fabiola F, Chapman MS, Ban N,
Frank J |
(2006) "Elongation
arrest by SecM via a cascade of ribosomal RNA
rearrangements." Mol.Cell,
22, 533-543. doi: 10.1016/j.molcel.2006.05.003.
|
Structure of a pre-translocational e. coli ribosome
obtained by fitting atomic models for RNA and protein
components into cryo-EM map emd-1056 . SNAP output
|
|
4v4w
|
ribosome |
cryo-EM (15.0 Å) |
Mitra K, Schaffitzel C, Fabiola F, Chapman MS, Ban N,
Frank J |
(2006) "Elongation
arrest by SecM via a cascade of ribosomal RNA
rearrangements." Mol.Cell,
22, 533-543. doi: 10.1016/j.molcel.2006.05.003.
|
Structure of a secm-stalled e. coli ribosome complex
obtained by fitting atomic models for RNA and protein
components into cryo-EM map emd-1143 . SNAP output
|
|
4v4x
|
ribosome |
X-ray (5.0 Å) |
Yusupova G, Jenner L, Rees B, Moras D, Yusupov M |
(2006) "Structural
basis for messenger RNA movement on the ribosome."
Nature, 444, 391-394. doi:
10.1038/nature05281.
|
Crystal structure of the 70s thermus thermophilus
ribosome showing how the 16s 3'-end mimicks mrna e and
p codons. . SNAP
output
|
|
4v4y
|
ribosome |
X-ray (5.5 Å) |
Yusupova G, Jenner L, Rees B, Moras D, Yusupov M |
(2006) "Structural
basis for messenger RNA movement on the ribosome."
Nature, 444, 391-394. doi:
10.1038/nature05281.
|
Crystal structure of the 70s thermus thermophilus
ribosome with translocated and rotated shine-dalgarno
duplex. . SNAP
output
|
|
4v4z
|
ribosome |
X-ray (4.51 Å) |
Yusupova G, Jenner L, Rees B, Moras D, Yusupov M |
(2006) "Structural
basis for messenger RNA movement on the ribosome."
Nature, 444, 391-394. doi:
10.1038/nature05281.
|
70s thermus thermophilous ribosome functional complex
with mrna and e- and p-site trnas at 4.5a. . SNAP output
|
|
4v50
|
ribosome |
X-ray (3.22 Å) |
Berk V, Zhang W, Pai RD, Cate JHD |
(2006) "Structural
basis for mRNA and tRNA positioning on the
ribosome." Proc.Natl.Acad.Sci.Usa,
103, 15830-15834. doi: 10.1073/pnas.0607541103.
|
Crystal structure of ribosome with messenger RNA and
the anticodon stem-loop of p-site trna. . SNAP output
|
|
4v51
|
ribosome |
X-ray (2.8 Å) |
Selmer M, Dunham CM, Murphy FV, Weixlbaumer A, Petry
S, Kelley AC, Weir JR, Ramakrishnan V |
(2006) "Structure
of the 70S ribosome complexed with mRNA and tRNA."
Science, 313, 1935-1942. doi:
10.1126/science.1131127.
|
Structure of the thermus thermophilus 70s ribosome
complexed with mrna, trna and paromomycin . SNAP output
|
|
4v52
|
ribosome |
X-ray (3.21 Å) |
Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS,
Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH |
(2007) "Structural
basis for aminoglycoside inhibition of bacterial
ribosome recycling." Nat.Struct.Mol.Biol.,
14, 727-732. doi: 10.1038/nsmb1271.
|
Crystal structure of the bacterial ribosome from
escherichia coli in complex with neomycin. . SNAP output
|
|
4v53
|
ribosome |
X-ray (3.54 Å) |
Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS,
Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH |
(2007) "Structural
basis for aminoglycoside inhibition of bacterial
ribosome recycling." Nat.Struct.Mol.Biol.,
14, 727-732. doi: 10.1038/nsmb1271.
|
Crystal structure of the bacterial ribosome from
escherichia coli in complex with gentamicin. . SNAP output
|
|
4v54
|
ribosome |
X-ray (3.3 Å) |
Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS,
Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH |
(2007) "Structural
basis for aminoglycoside inhibition of bacterial
ribosome recycling." Nat.Struct.Mol.Biol.,
14, 727-732. doi: 10.1038/nsmb1271.
|
Crystal structure of the bacterial ribosome from
escherichia coli in complex with ribosome recycling
factor (rrf). . SNAP
output
|
|
4v55
|
ribosome |
X-ray (4.0 Å) |
Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS,
Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH |
(2007) "Structural
basis for aminoglycoside inhibition of bacterial
ribosome recycling." Nat.Struct.Mol.Biol.,
14, 727-732. doi: 10.1038/nsmb1271.
|
Crystal structure of the bacterial ribosome from
escherichia coli in complex with gentamicin and
ribosome recycling factor (rrf). . SNAP output
|
|
4v56
|
ribosome |
X-ray (3.93 Å) |
Borovinskaya MA, Shoji S, Holton JM, Fredrick K, Cate
JH |
(2007) "A steric
block in translation caused by the antibiotic
spectinomycin." Acs Chem.Biol.,
2, 545-552. doi: 10.1021/cb700100n.
|
Crystal structure of the bacterial ribosome from
escherichia coli in complex with spectinomycin. .
SNAP output
|
|
4v57
|
ribosome |
X-ray (3.5 Å) |
Borovinskaya MA, Shoji S, Holton JM, Fredrick K, Cate
JH |
(2007) "A steric
block in translation caused by the antibiotic
spectinomycin." Acs Chem.Biol.,
2, 545-552. doi: 10.1021/cb700100n.
|
Crystal structure of the bacterial ribosome from
escherichia coli in complex with spectinomycin and
neomycin. . SNAP
output
|
|
4v5a
|
ribosome |
X-ray (3.5 Å) |
Weixlbaumer A, Petry S, Dunham CM, Selmer M, Kelley
AC, Ramakrishnan V |
(2007) "Crystal
structure of the ribosome recycling factor bound to the
ribosome." Nat. Struct. Mol. Biol.,
14, 733-737. doi: 10.1038/nsmb1282.
|
Structure of the ribosome recycling factor bound to the
thermus thermophilus 70s ribosome with mrna, asl-phe
and trna-fmet . SNAP
output
|
|
4v5b
|
ribosome |
X-ray (3.74 Å) |
Bingel-Erlenmeyer R, Kohler R, Kramer G, Sandikci A,
Antolic S, Maier T, Schaffitzel C, Wiedmann B, Bukau B,
Ban N |
(2008) "A
Peptide Deformylase-Ribosome Complex Reveals Mechanism
of Nascent Chain Processing." Nature,
452, 108-111. doi: 10.1038/nature06683.
|
Structure of pdf binding helix in complex with the
ribosome. . SNAP
output
|
|
4v5c
|
ribosome |
X-ray (3.3 Å) |
Voorhees RM, Weixlbaumer A, Loakes D, Kelley AC,
Ramakrishnan V |
(2009) "Insights
Into Substrate Stabilization from Snapshots of the
Peptidyl Transferase Center of the Intact 70S
Ribosome." Nat.Struct.Mol.Biol.,
16, 528-533. doi: 10.1038/nsmb.1577.
|
Structure of the thermus thermophilus 70s ribosome in
complex with mrna, paromomycin, acylated a-site trna,
deacylated p-site trna, and e-site trna. . SNAP output
|
|
4v5d
|
ribosome |
X-ray (3.5 Å) |
Voorhees RM, Weixlbaumer A, Loakes D, Kelley AC,
Ramakrishnan V |
(2009) "Insights
into substrate stabilization from snapshots of the
peptidyl transferase center of the intact 70S
ribosome." Nat. Struct. Mol. Biol.,
16, 528-533. doi: 10.1038/nsmb.1577.
|
Structure of the thermus thermophilus 70s ribosome in
complex with mrna, paromomycin, acylated a- and p-site
trnas, and e-site trna. . SNAP output
|
|
4v5e
|
ribosome |
X-ray (3.45 Å) |
Weixlbaumer A, Jin H, Neubauer C, Voorhees RM, Petry
S, Kelley AC, Ramakrishnan V |
(2008) "Insights
Into Translational Termination from the Structure of
Rf2 Bound to the Ribosome." Science,
322, 953-956. doi: 10.1126/science.1164840.
|
Insights into translational termination from the
structure of rf2 bound to the ribosome . SNAP output
|
|
4v5f
|
ribosome |
X-ray (3.6 Å) |
Gao YG, Selmer M, Dunham CM, Weixlbaumer A, Kelley
AC, Ramakrishnan V |
(2009) "The
structure of the ribosome with elongation factor G
trapped in the posttranslocational state."
Science, 326, 694-699. doi:
10.1126/science.1179709.
|
The structure of the ribosome with elongation factor g
trapped in the post-translocational state . SNAP output
|
|
4v5g
|
ribosome |
X-ray (3.6 Å) |
Schmeing TM, Voorhees RM, Kelley AC, Gao YG, Murphy
FV, Weir JR, Ramakrishnan V |
(2009) "The
crystal structure of the ribosome bound to EF-Tu and
aminoacyl-tRNA." Science,
326, 688-694. doi: 10.1126/science.1179700.
|
The crystal structure of the 70s ribosome bound to
ef-tu and trna . SNAP
output
|
|
4v5h
|
ribosome |
cryo-EM (5.8 Å) |
Seidelt B, Innis CA, Wilson DN, Gartmann M, Armache
JP, Villa E, Trabuco LG, Becker T, Mielke T, Schulten K,
Steitz TA, Beckmann R |
(2009) "Structural
insight into nascent polypeptide chain-mediated
translational stalling." Science,
326, 1412-1415. doi: 10.1126/science.1177662.
|
E.coli 70s ribosome stalled during translation of tnac
leader peptide. . SNAP
output
|
|
4v5j
|
ribosome |
X-ray (3.1 Å) |
Jin H, Kelley AC, Loakes D, Ramakrishnan V |
(2010) "Structure
of the 70S ribosome bound to release factor 2 and a
substrate analog provides insights into catalysis of
peptide release." Proc. Natl. Acad. Sci.
U.S.A., 107, 8593-8598. doi:
10.1073/pnas.1003995107.
|
Structure of the 70s ribosome bound to release factor 2
and a substrate analog provides insights into catalysis
of peptide release . SNAP output
|
|
4v5k
|
ribosome |
X-ray (3.2 Å) |
Ng CL, Lang K, Meenan NAG, Sharma A, Kelley AC,
Kleanthous C, Ramakrishnan V |
(2010) "Structural
Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic
Domain of Colicin E3."
Nat.Struct.Mol.Biol., 17,
1241-1246. doi: 10.1038/nsmb.1896.
|
Structure of cytotoxic domain of colicin e3 bound to
the 70s ribosome . SNAP
output
|
|
4v5l
|
ribosome |
X-ray (3.1 Å) |
Voorhees RM, Schmeing TM, Kelley AC, Ramakrishnan
V |
(2010) "The
Mechanism for Activation of GTP Hydrolysis on the
Ribosome." Science, 330,
835. doi: 10.1126/SCIENCE.1194460.
|
The structure of ef-tu and aminoacyl-trna bound to the
70s ribosome with a gtp analog . SNAP output
|
|
4v5m
|
ribosome |
cryo-EM (7.8 Å) |
Ratje AH, Loerke J, Mikolajka A, Brunner M,
Hildebrand PW, Starosta AL, Donhofer A, Connell SR,
Fucini P, Mielke T, Whitford PC, Onuchic JN, Yu Y,
Sanbonmatsu KY, Hartmann RK, Penczek PA, Wilson DN, Spahn
CMT |
(2010) "Head
Swivel on the Ribosome Facilitates Translocation by
Means of Intra-Subunit tRNA Hybrid Sites."
Nature, 468, 713. doi:
10.1038/NATURE09547.
|
Trna tranlocation on the 70s ribosome: the
pre-translocational translocation intermediate ti(pre)
. SNAP output
|
|
4v5n
|
ribosome |
cryo-EM (7.6 Å) |
Ratje AH, Loerke J, Mikolajka A, Brunner M,
Hildebrand PW, Starosta AL, Donhofer A, Connell SR,
Fucini P, Mielke T, Whitford PC, Onuchic JN, Yu Y,
Sanbonmatsu KY, Hartmann RK, Penczek PA, Wilson DN, Spahn
CMT |
(2010) "Head
Swivel on the Ribosome Facilitates Translocation by
Means of Intra-Subunit tRNA Hybrid Sites."
Nature, 468, 713. doi:
10.1038/NATURE09547.
|
Trna translocation on the 70s ribosome: the post-
translocational translocation intermediate ti(post) .
SNAP output
|
|
4v5o
|
ribosome |
X-ray (3.93 Å) |
Rabl J, Leibundgut M, Ataide SF, Haag A, Ban N |
(2011) "Crystal
Structure of the Eukaryotic 40S Ribosomal Subunit in
Complex with Initiation Factor 1."
Science, 331, 730. doi:
10.1126/SCIENCE.1198308.
|
Crystal structure of the eukaryotic 40s ribosomal
subunit in complex with initiation factor 1. . SNAP output
|
|
4v5p
|
ribosome |
X-ray (3.1 Å) |
Schmeing TM, Voorhees RM, Kelley AC, Ramakrishnan
V |
(2011) "How
Mutations in tRNA Distant from the Anticodon Affect the
Fidelity of Decoding."
Nat.Struct.Mol.Biol., 18,
432. doi: 10.1038/NSMB.2003.
|
The crystal structure of ef-tu and a9c-trna-trp bound
to a near- cognate codon on the 70s ribosome . SNAP output
|
|
4v5q
|
ribosome |
X-ray (3.1 Å) |
Schmeing TM, Voorhees RM, Kelley AC, Ramakrishnan
V |
(2011) "How
Mutations in tRNA Distant from the Anticodon Affect the
Fidelity of Decoding."
Nat.Struct.Mol.Biol., 18,
432. doi: 10.1038/NSMB.2003.
|
The crystal structure of ef-tu and g24a-trna-trp bound
to a near- cognate codon on the 70s ribosome . SNAP output
|
|
4v5r
|
ribosome |
X-ray (3.1 Å) |
Schmeing TM, Voorhees RM, Kelley AC, Ramakrishnan
V |
(2011) "How
Mutations in tRNA Distant from the Anticodon Affect the
Fidelity of Decoding."
Nat.Struct.Mol.Biol., 18,
432. doi: 10.1038/NSMB.2003.
|
The crystal structure of ef-tu and trp-trna-trp bound
to a cognate codon on the 70s ribosome. . SNAP output
|
|
4v5s
|
ribosome |
X-ray (3.1 Å) |
Schmeing TM, Voorhees RM, Kelley AC, Ramakrishnan
V |
(2011) "How
Mutations in tRNA Distant from the Anticodon Affect the
Fidelity of Decoding."
Nat.Struct.Mol.Biol., 18,
432. doi: 10.1038/NSMB.2003.
|
The crystal structure of ef-tu and g24a-trna-trp bound
to a cognate codon on the 70s ribosome. . SNAP output
|
|
4v5v
|
viral protein-RNA |
X-ray (3.6 Å) |
El Omari K, Dhaliwal B, Ren J, Abrescia NGA, Lockyer
M, Powell KL, Hawkins AR, Stammers DK |
(2011) "Structures
of Respiratory Syncytial Virus Nucleocapsid Protein
from Two Crystal Forms: Details of Potential Packing
Interactions in the Native Helical Form." Acta
Crystallogr.,Sect.F, 67, 1179.
doi: 10.1107/S1744309111029228.
|
Structure of respiratory syncytial virus nucleocapsid
protein, p1 crystal form . SNAP output
|
|
4v5y
|
ribosome |
X-ray (4.45 Å) |
Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS,
Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH |
(2007) "Structural
basis for aminoglycoside inhibition of bacterial
ribosome recycling." Nat.Struct.Mol.Biol.,
14, 727-732. doi: 10.1038/nsmb1271.
|
Crystal structure of the bacterial ribosome from
escherichia coli in complex with paromomycin and
ribosome recycling factor (rrf). . SNAP output
|
|
4v61
|
ribosome |
cryo-EM (9.4 Å) |
Sharma MR, Wilson DN, Datta PP, Barat C, Schluenzen
F, Fucini P, Agrawal RK |
(2007) "Cryo-EM
study of the spinach chloroplast ribosome reveals the
structural and functional roles of plastid-specific
ribosomal proteins."
Proc.Natl.Acad.Sci.Usa, 104,
19315-19320. doi: 10.1073/pnas.0709856104.
|
Homology model for the spinach chloroplast 30s subunit
fitted to 9.4a cryo-EM map of the 70s chlororibosome. .
SNAP output
|
|
4v63
|
ribosome |
X-ray (3.207 Å) |
Laurberg M, Asahara H, Korostelev A, Zhu J, Trakhanov
S, Noller HF |
(2008) "Structural
basis for translation termination on the 70S
ribosome." Nature, 454,
852-857. doi: 10.1038/nature07115.
|
Structural basis for translation termination on the 70s
ribosome. . SNAP
output
|
|
4v64
|
ribosome |
X-ray (3.5 Å) |
Borovinskaya MA, Shoji S, Fredrick K, Cate JHD |
(2008) "Structural
basis for hygromycin B inhibition of protein
biosynthesis." Rna, 14,
1590-1599. doi: 10.1261/rna.1076908.
|
Crystal structure of the bacterial ribosome from
escherichia coli in complex with hygromycin b. .
SNAP output
|
|
4v65
|
ribosome |
cryo-EM (9.0 Å) |
Devkota B, Caulfield TR, Tan R-Z, Harvey SC |
"The Structure of the E. coli Ribosome Before and
After Accommodation: Implications for Proofreading." |
Structure of the e. coli ribosome in the
pre-accommodation state . SNAP output
|
|
4v66
|
ribosome |
cryo-EM (9.0 Å) |
Devkota B, Caulfield TR, Tan R-Z, Harvey SC |
"The Structure of the E. coli Ribosome Before and
After Accommodation: Implications for Proofreading." |
Structure of the e. coli ribosome and the trnas in
post-accommodation state . SNAP output
|
|
4v67
|
ribosome |
X-ray (3.0 Å) |
Korostelev A, Asahara H, Lancaster L, Laurberg M,
Hirschi A, Zhu J, Trakhanov S, Scott WG, Noller HF |
(2008) "Crystal
structure of a translation termination complex formed
with release factor RF2."
Proc.Natl.Acad.Sci.USA, 105,
19684-19689. doi: 10.1073/pnas.0810953105.
|
Crystal structure of a translation termination complex
formed with release factor rf2. . SNAP output
|
|
4v68
|
ribosome |
cryo-EM (6.4 Å) |
Schuette JC, Murphy FV, Kelley AC, Weir JR,
Giesebrecht J, Connell SR, Loerke J, Mielke T, Zhang W,
Penczek PA, Ramakrishnan V, Spahn CM |
(2009) "GTPase
activation of elongation factor EF-Tu by the ribosome
during decoding." Embo J.,
28, 755-765. doi: 10.1038/emboj.2009.26.
|
T. thermophilus 70s ribosome in complex with mrna,
trnas and ef-tu.gdp.kirromycin ternary complex, fitted
to a 6.4 a cryo-EM map. . SNAP output
|
|
4v69
|
ribosome |
cryo-EM (6.7 Å) |
Villa E, Sengupta J, Trabuco LG, LeBarron J, Baxter
WT, Shaikh TR, Grassucci RA, Nissen P, Ehrenberg M,
Schulten K, Frank J |
(2009) "Ribosome-induced
changes in elongation factor Tu conformation control
GTP hydrolysis." Proc.Natl.Acad.Sci.USA,
106, 1063-1068. doi: 10.1073/pnas.0811370106.
|
Ternary complex-bound e.coli 70s ribosome. . SNAP output
|
|
4v6a
|
ribosome |
X-ray (3.1 Å) |
Blaha G, Stanley RE, Steitz TA |
(2009) "Formation
of the first peptide bond: the structure of EF-P bound
to the 70S ribosome." Science,
325, 966-970. doi: 10.1126/science.1175800.
|
Structure of ef-p bound to the 70s ribosome. . SNAP output
|
|
4v6c
|
ribosome |
X-ray (3.19 Å) |
Zhang W, Dunkle JA, Cate JH |
(2009) "Structures
of the ribosome in intermediate States of
ratcheting." Science,
325, 1014-1017. doi: 10.1126/science.1175275.
|
Crystal structure of the e. coli 70s ribosome in an
intermediate state of ratcheting . SNAP output
|
|
4v6d
|
ribosome |
X-ray (3.814 Å) |
Zhang W, Dunkle JA, Cate JH |
(2009) "Structures
of the ribosome in intermediate States of
ratcheting." Science,
325, 1014-1017. doi: 10.1126/science.1175275.
|
Crystal structure of the e. coli 70s ribosome in an
intermediate state of ratcheting . SNAP output
|
|
4v6e
|
ribosome |
X-ray (3.712 Å) |
Zhang W, Dunkle JA, Cate JH |
(2009) "Structures
of the ribosome in intermediate States of
ratcheting." Science,
325, 1014-1017. doi: 10.1126/science.1175275.
|
Crystal structure of the e. coli 70s ribosome in an
intermediate state of ratcheting . SNAP output
|
|
4v6f
|
ribosome |
X-ray (3.1 Å) |
Jenner LB, Demeshkina N, Yusupova G, Yusupov M |
(2010) "Structural
aspects of messenger RNA reading frame maintenance by
the ribosome." Nat.Struct.Mol.Biol.,
17, 555-560. doi: 10.1038/nsmb.1790.
|
Elongation complex of the 70s ribosome with three trnas
and mrna. . SNAP
output
|
|
4v6g
|
ribosome |
X-ray (3.5 Å) |
Jenner LB, Demeshkina N, Yusupova G, Yusupov M |
(2010) "Structural
aspects of messenger RNA reading frame maintenance by
the ribosome." Nat.Struct.Mol.Biol.,
17, 555-560. doi: 10.1038/nsmb.1790.
|
Initiation complex of 70s ribosome with two trnas and
mrna. . SNAP output
|
|
4v6k
|
ribosome |
cryo-EM (8.25 Å) |
Agirrezabala X, Schreiner E, Trabuco LG, Lei J,
Ortiz-Meoz RF, Schulten K, Green R, Frank J |
(2011) "Structural
insights into cognate versus near-cognate
discrimination during decoding." Embo J.,
30, 1497-1507. doi: 10.1038/emboj.2011.58.
|
Structural insights into cognate vs. near-cognate
discrimination during decoding. . SNAP output
|
|
4v6l
|
ribosome |
cryo-EM (13.2 Å) |
Agirrezabala X, Schreiner E, Trabuco LG, Lei J,
Ortiz-Meoz RF, Schulten K, Green R, Frank J |
(2011) "Structural
insights into cognate versus near-cognate
discrimination during decoding." Embo J.,
30, 1497-1507. doi: 10.1038/emboj.2011.58.
|
Structural insights into cognate vs. near-cognate
discrimination during decoding. . SNAP output
|
|
4v6m
|
ribosome-ribosomal protein |
cryo-EM (7.1 Å) |
Frauenfeld J, Gumbart J, Sluis EO, Funes S, Gartmann
M, Beatrix B, Mielke T, Berninghausen O, Becker T,
Schulten K, Beckmann R |
(2011) "Cryo-EM
structure of the ribosome-SecYE complex in the membrane
environment." Nat.Struct.Mol.Biol.,
18, 614-621. doi: 10.1038/nsmb.2026.
|
Structure of the ribosome-secye complex in the membrane
environment . SNAP
output
|
|
4v6n
|
ribosome |
cryo-EM (12.1 Å) |
Agirrezabala X, Liao HY, Schreiner E, Fu J,
Ortiz-Meoz RF, Schulten K, Green R, Frank J |
(2012) "Structural
characterization of mRNA-tRNA translocation
intermediates." Proc.Natl.Acad.Sci.USA,
109, 6094-6099. doi: 10.1073/pnas.1201288109.
|
Structural characterization of mrna-trna translocation
intermediates (50s ribosome of class2 of the six
classes) . SNAP
output
|
|
4v6o
|
ribosome |
cryo-EM (14.7 Å) |
Agirrezabala X, Liao HY, Schreiner E, Fu J,
Ortiz-Meoz RF, Schulten K, Green R, Frank J |
(2012) "Structural
characterization of mRNA-tRNA translocation
intermediates." Proc.Natl.Acad.Sci.USA,
109, 6094-6099. doi: 10.1073/pnas.1201288109.
|
Structural characterization of mrna-trna translocation
intermediates (class 4a of the six classes) . SNAP output
|
|
4v6p
|
ribosome |
cryo-EM (13.5 Å) |
Agirrezabala X, Liao HY, Schreiner E, Fu J,
Ortiz-Meoz RF, Schulten K, Green R, Frank J |
(2012) "Structural
characterization of mRNA-tRNA translocation
intermediates." Proc.Natl.Acad.Sci.USA,
109, 6094-6099. doi: 10.1073/pnas.1201288109.
|
Structural characterization of mrna-trna translocation
intermediates (class 4b of the six classes) . SNAP output
|
|
4v6q
|
ribosome |
cryo-EM (11.5 Å) |
Agirrezabala X, Liao HY, Schreiner E, Fu J,
Ortiz-Meoz RF, Schulten K, Green R, Frank J |
(2012) "Structural
characterization of mRNA-tRNA translocation
intermediates." Proc.Natl.Acad.Sci.USA,
109, 6094-6099. doi: 10.1073/pnas.1201288109.
|
Structural characterization of mrna-trna translocation
intermediates (class 5 of the six classes) . SNAP output
|
|
4v6r
|
ribosome |
cryo-EM (11.5 Å) |
Agirrezabala X, Liao HY, Schreiner E, Fu J,
Ortiz-Meoz RF, Schulten K, Green R, Frank J |
(2012) "Structural
characterization of mRNA-tRNA translocation
intermediates." Proc.Natl.Acad.Sci.USA,
109, 6094-6099. doi: 10.1073/pnas.1201288109.
|
Structural characterization of mrna-trna translocation
intermediates (class 6 of the six classes) . SNAP output
|
|
4v6s
|
ribosome |
cryo-EM (13.1 Å) |
Agirrezabala X, Liao HY, Schreiner E, Fu J,
Ortiz-Meoz RF, Schulten K, Green R, Frank J |
(2012) "Structural
characterization of mRNA-tRNA translocation
intermediates." Proc.Natl.Acad.Sci.USA,
109, 6094-6099. doi: 10.1073/pnas.1201288109.
|
Structural characterization of mrna-trna translocation
intermediates (class 3 of the six classes) . SNAP output
|
|
4v6t
|
ribosome |
cryo-EM (8.3 Å) |
Ramrath DJ, Yamamoto H, Rother K, Wittek D, Pech M,
Mielke T, Loerke J, Scheerer P, Ivanov P, Teraoka Y,
Shpanchenko O, Nierhaus KH, Spahn CM |
(2012) "The
complex of tmRNA-SmpB and EF-G on translocating
ribosomes." Nature, 485,
526-529. doi: 10.1038/nature11006.
|
Structure of the bacterial ribosome complexed by
tmrna-smpb and ef-g during translocation and
mld-loading . SNAP
output
|
|
4v6u
|
ribosome |
cryo-EM (6.6 Å) |
Armache J-P, Anger AM, Marquez V, Franckenberg S,
Frohlich T, Villa E, Berninghausen O, Thomm M, Arnold GJ,
Beckmann R, Wilson DN |
(2013) "Promiscuous
behaviour of archaeal ribosomal proteins: Implications
for eukaryotic ribosome evolution." Nucleic
Acids Res., 41, 1284-1293. doi:
10.1093/nar/gks1259.
|
Promiscuous behavior of proteins in archaeal ribosomes
revealed by cryo-EM: implications for evolution of
eukaryotic ribosomes . SNAP output
|
|
4v6v
|
ribosome |
cryo-EM (9.8 Å) |
Li W, Atkinson GC, Thakor NS, Allas U, Lu CC, Chan
KY, Tenson T, Schulten K, Wilson KS, Hauryliuk V, Frank
J |
(2013) "Mechanism
of tetracycline resistance by ribosomal protection
protein Tet(O)." Nat Commun,
4, 1477. doi: 10.1038/ncomms2470.
|
Tetracycline resistance protein tet(o) bound to the
ribosome . SNAP
output
|
|
4v6y
|
ribosome |
cryo-EM (12.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in classic
pre-translocation state (pre1a) . SNAP output
|
|
4v6z
|
ribosome |
cryo-EM (12.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in classic
pre-translocation state (pre1b) . SNAP output
|
|
4v70
|
ribosome |
cryo-EM (17.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in
intermediate pre-translocation state (pre3) . SNAP output
|
|
4v71
|
ribosome |
cryo-EM (20.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in
intermediate pre-translocation state (pre2) . SNAP output
|
|
4v72
|
ribosome |
cryo-EM (13.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in hybrid
pre-translocation state (pre4) . SNAP output
|
|
4v73
|
ribosome |
cryo-EM (15.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in hybrid
pre-translocation state (pre5a) . SNAP output
|
|
4v74
|
ribosome |
cryo-EM (17.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
70s-fmetval-trnaval-trnafmet complex in hybrid
pre-translocation state (pre5b) . SNAP output
|
|
4v75
|
ribosome |
cryo-EM (12.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in classic
post-translocation state (post1) . SNAP output
|
|
4v76
|
ribosome |
cryo-EM (17.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in
intermediate post-translocation state (post2a) .
SNAP output
|
|
4v77
|
ribosome |
cryo-EM (17.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in
intermediate post-translocation state (post2b) .
SNAP output
|
|
4v78
|
ribosome |
cryo-EM (20.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in
intermediate post-translocation state (post3a) .
SNAP output
|
|
4v79
|
ribosome |
cryo-EM (15.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval-trnafmet complex in
intermediate post-translocation state (post3b) .
SNAP output
|
|
4v7a
|
ribosome |
cryo-EM (9.0 Å) |
Bock LV, Blau C, Schroder GF, Davydov II, Fischer N,
Stark H, Rodnina MV, Vaiana AC, Grubmuller H |
(2013) "Energy
barriers and driving forces in tRNA translocation
through the ribosome."
Nat.Struct.Mol.Biol., 20,
1390-1396. doi: 10.1038/nsmb.2690.
|
E. coli 70s-fmetval-trnaval post-translocation complex
(post4) . SNAP
output
|
|
4v7b
|
ribosome-translation |
cryo-EM (6.8 Å) |
Ramrath DJ, Lancaster L, Sprink T, Mielke T, Loerke
J, Noller HF, Spahn CM |
(2013) "Visualization
of two transfer RNAs trapped in transit during
elongation factor G-mediated translocation."
Proc.Natl.Acad.Sci.USA, 110,
20964-20969. doi: 10.1073/pnas.1320387110.
|
Visualization of two trnas trapped in transit during
ef-g-mediated translocation . SNAP output
|
|
4v7c
|
translation |
cryo-EM (7.6 Å) |
Brilot AF, Korostelev AA, Ermolenko DN, Grigorieff
N |
(2013) "Structure
of the ribosome with elongation factor G trapped in the
pretranslocation state."
Proc.Natl.Acad.Sci.USA, 110,
20994-20999. doi: 10.1073/pnas.1311423110.
|
Structure of the ribosome with elongation factor g
trapped in the pre-translocation state
(pre-translocation 70s*trna structure) . SNAP output
|
|
4v7d
|
translation-antibiotic |
cryo-EM (7.6 Å) |
Brilot AF, Korostelev AA, Ermolenko DN, Grigorieff
N |
(2013) "Structure
of the ribosome with elongation factor G trapped in the
pretranslocation state."
Proc.Natl.Acad.Sci.USA, 110,
20994-20999. doi: 10.1073/pnas.1311423110.
|
Structure of the ribosome with elongation factor g
trapped in the pre-translocation state
(pre-translocation 70s*trna*ef-g structure) . SNAP output
|
|
4v7e
|
ribosome |
cryo-EM (5.5 Å) |
Gogala M, Becker T, Beatrix B, Armache J-P,
Barrio-Garcia C, Berninghausen O, Beckmann R |
(2014) "Structures
of the Sec61 complex engaged in nascent peptide
translocation or membrane insertion."
Nature, 506, 107-110. doi:
10.1038/nature12950.
|
Model of the small subunit RNA based on a 5.5 a cryo-EM
map of triticum aestivum translating 80s ribosome .
SNAP output
|
|
4v7i
|
ribosome |
cryo-EM (9.6 Å) |
Gumbart J, Trabuco LG, Schreiner E, Villa E, Schulten
K |
(2009) "Regulation
of the protein-conducting channel by a bound
ribosome." Structure, 17,
1453-1464. doi: 10.1016/j.str.2009.09.010.
|
Ribosome-secy complex. . SNAP output
|
|
4v7j
|
ribosome |
X-ray (3.3 Å) |
Neubauer C, Gao YG, Andersen KR, Dunham CM, Kelley
AC, Hentschel J, Gerdes K, Ramakrishnan V, Brodersen
DE |
(2009) "The
structural basis for mRNA recognition and cleavage by
the ribosome-dependent endonuclease RelE."
Cell(Cambridge,Mass.), 139,
1084-1095. doi: 10.1016/j.cell.2009.11.015.
|
Structure of rele nuclease bound to the 70s ribosome
(precleavage state) . SNAP output
|
|
4v7k
|
ribosome |
X-ray (3.6 Å) |
Neubauer C, Gao YG, Andersen KR, Dunham CM, Kelley
AC, Hentschel J, Gerdes K, Ramakrishnan V, Brodersen
DE |
(2009) "The
structural basis for mRNA recognition and cleavage by
the ribosome-dependent endonuclease RelE."
Cell(Cambridge,Mass.), 139,
1084-1095. doi: 10.1016/j.cell.2009.11.015.
|
Structure of rele nuclease bound to the 70s ribosome
(postcleavage state) . SNAP output
|
|
4v7l
|
ribosome-antibiotic |
X-ray (3.0 Å) |
Stanley RE, Blaha G, Grodzicki RL, Strickler MD,
Steitz TA |
(2010) "The
structures of the anti-tuberculosis antibiotics
viomycin and capreomycin bound to the 70S
ribosome." Nat.Struct.Mol.Biol.,
17, 289-293. doi: 10.1038/nsmb.1755.
|
The structures of viomycin bound to the 70s ribosome. .
SNAP output
|
|
4v7m
|
ribosome-antibiotic |
X-ray (3.45 Å) |
Stanley RE, Blaha G, Grodzicki RL, Strickler MD,
Steitz TA |
(2010) "The
structures of the anti-tuberculosis antibiotics
viomycin and capreomycin bound to the 70S
ribosome." Nat.Struct.Mol.Biol.,
17, 289-293. doi: 10.1038/nsmb.1755.
|
The structures of capreomycin bound to the 70s
ribosome. . SNAP
output
|
|
4v7p
|
ribosome |
X-ray (3.62 Å) |
Korostelev A, Zhu J, Asahara H, Noller HF |
(2010) "Recognition
of the amber UAG stop codon by release factor RF1."
Embo J., 29, 2577-2585. doi:
10.1038/emboj.2010.139.
|
Recognition of the amber stop codon by release factor
rf1. . SNAP output
|
|
4v7r
|
ribosome |
X-ray (4.0 Å) |
Ben-Shem A, Jenner L, Yusupova G, Yusupov M |
(2010) "Crystal
structure of the eukaryotic ribosome."
Science, 330, 1203-1209. doi:
10.1126/science.1194294.
|
Yeast 80s ribosome. . SNAP output
|
|
4v7s
|
ribosome-antibiotic |
X-ray (3.25 Å) |
Dunkle JA, Xiong L, Mankin AS, Cate JH |
(2010) "Structures
of the Escherichia coli ribosome with antibiotics bound
near the peptidyl transferase center explain spectra of
drug action." Proc.Natl.Acad.Sci.USA,
107, 17152-17157. doi: 10.1073/pnas.1007988107.
|
Crystal structure of the e. coli ribosome bound to
telithromycin. . SNAP
output
|
|
4v7t
|
ribosome-antibiotic |
X-ray (3.19 Å) |
Dunkle JA, Xiong L, Mankin AS, Cate JH |
(2010) "Structures
of the Escherichia coli ribosome with antibiotics bound
near the peptidyl transferase center explain spectra of
drug action." Proc.Natl.Acad.Sci.USA,
107, 17152-17157. doi: 10.1073/pnas.1007988107.
|
Crystal structure of the e. coli ribosome bound to
chloramphenicol. . SNAP
output
|
|
4v7u
|
ribosome |
X-ray (3.1 Å) |
Dunkle JA, Xiong L, Mankin AS, Cate JH |
(2010) "Structures
of the Escherichia coli ribosome with antibiotics bound
near the peptidyl transferase center explain spectra of
drug action." Proc.Natl.Acad.Sci.USA,
107, 17152-17157. doi: 10.1073/pnas.1007988107.
|
Crystal structure of the e. coli ribosome bound to
erythromycin. . SNAP
output
|
|
4v7v
|
ribosome-antibiotic |
X-ray (3.29 Å) |
Dunkle JA, Xiong L, Mankin AS, Cate JH |
(2010) "Structures
of the Escherichia coli ribosome with antibiotics bound
near the peptidyl transferase center explain spectra of
drug action." Proc.Natl.Acad.Sci.USA,
107, 17152-17157. doi: 10.1073/pnas.1007988107.
|
Crystal structure of the e. coli ribosome bound to
clindamycin. . SNAP
output
|
|
4v7w
|
ribosome-antibiotic |
X-ray (3.0 Å) |
Bulkley D, Innis CA, Blaha G, Steitz TA |
(2010) "Revisiting
the structures of several antibiotics bound to the
bacterial ribosome."
Proc.Natl.Acad.Sci.USA, 107,
17158-17163. doi: 10.1073/pnas.1008685107.
|
Structure of the thermus thermophilus ribosome
complexed with chloramphenicol. . SNAP output
|
|
4v7x
|
ribosome-antibiotic |
X-ray (3.0 Å) |
Bulkley D, Innis CA, Blaha G, Steitz TA |
(2010) "Revisiting
the structures of several antibiotics bound to the
bacterial ribosome."
Proc.Natl.Acad.Sci.USA, 107,
17158-17163. doi: 10.1073/pnas.1008685107.
|
Structure of the thermus thermophilus ribosome
complexed with erythromycin. . SNAP output
|
|
4v7y
|
ribosome-antibiotic |
X-ray (3.0 Å) |
Bulkley D, Innis CA, Blaha G, Steitz TA |
(2010) "Revisiting
the structures of several antibiotics bound to the
bacterial ribosome."
Proc.Natl.Acad.Sci.USA, 107,
17158-17163. doi: 10.1073/pnas.1008685107.
|
Structure of the thermus thermophilus 70s ribosome
complexed with azithromycin. . SNAP output
|
|
4v7z
|
ribosome-antibiotic |
X-ray (3.1 Å) |
Bulkley D, Innis CA, Blaha G, Steitz TA |
(2010) "Revisiting
the structures of several antibiotics bound to the
bacterial ribosome."
Proc.Natl.Acad.Sci.USA, 107,
17158-17163. doi: 10.1073/pnas.1008685107.
|
Structure of the thermus thermophilus 70s ribosome
complexed with telithromycin. . SNAP output
|
|
4v83
|
ribosome |
X-ray (3.5 Å) |
Zhu J, Korostelev A, Costantino DA, Donohue JP,
Noller HF, Kieft JS |
(2011) "Crystal
structures of complexes containing domains from two
viral internal ribosome entry site (IRES) RNAs bound to
the 70S ribosome." Proc.Natl.Acad.Sci.USA,
108, 1839-1844. doi: 10.1073/pnas.1018582108.
|
Crystal structure of a complex containing domain 3 from
the psiv igr ires RNA bound to the 70s ribosome. .
SNAP output
|
|
4v84
|
ribosome |
X-ray (3.4 Å) |
Zhu J, Korostelev A, Costantino DA, Donohue JP,
Noller HF, Kieft JS |
(2011) "Crystal
structures of complexes containing domains from two
viral internal ribosome entry site (IRES) RNAs bound to
the 70S ribosome." Proc.Natl.Acad.Sci.USA,
108, 1839-1844. doi: 10.1073/pnas.1018582108.
|
Crystal structure of a complex containing domain 3 of
crpv igr ires RNA bound to the 70s ribosome. . SNAP output
|
|
4v85
|
ribosome-antibiotic |
X-ray (3.2 Å) |
Zhou J, Lancaster L, Trakhanov S, Noller HF |
(2012) "Crystal
structure of release factor RF3 trapped in the GTP
state on a rotated conformation of the ribosome."
Rna, 18, 230-240. doi:
10.1261/rna.031187.111.
|
Crystal structure of release factor rf3 trapped in the
gtp state on a rotated conformation of the ribosome. .
SNAP output
|
|
4v87
|
ribosome |
X-ray (3.1 Å) |
Demeshkina N, Jenner L, Westhof E, Yusupov M,
Yusupova G |
(2012) "A new
understanding of the decoding principle on the
ribosome." Nature, 484,
256-259. doi: 10.1038/nature10913.
|
Crystal structure analysis of ribosomal decoding. .
SNAP output
|
|
4v88
|
ribosome |
X-ray (3.0 Å) |
Ben-Shem A, Garreau de Loubresse N, Melnikov S,
Jenner L, Yusupova G, Yusupov M |
(2011) "The
structure of the eukaryotic ribosome at 3.0 angstrom
resolution." Science,
334, 1524-1529.
|
The structure of the eukaryotic ribosome at 3.0 Å
resolution. . SNAP
output
|
|
4v89
|
ribosome |
X-ray (3.7 Å) |
Zhou J, Lancaster L, Trakhanov S, Noller HF |
(2012) "Crystal
structure of release factor RF3 trapped in the GTP
state on a rotated conformation of the ribosome."
Rna, 18, 230-240. doi:
10.1261/rna.031187.111.
|
Crystal structure of release factor rf3 trapped in the
gtp state on a rotated conformation of the ribosome
(without viomycin) . SNAP output
|
|
4v8a
|
ribosome-antibiotic |
X-ray (3.2 Å) |
Bulkley D, Johnson F, Steitz TA |
(2012) "The
antibiotic thermorubin inhibits protein synthesis by
binding to inter-subunit bridge b2a of the
ribosome." J.Mol.Biol.,
416, 571-578. doi: 10.1016/j.jmb.2011.12.055.
|
The structure of thermorubin in complex with the 70s
ribosome from thermus thermophilus. . SNAP output
|
|
4v8b
|
ribosome |
X-ray (3.0 Å) |
Demeshkina N, Jenner L, Westhof E, Yusupov M,
Yusupova G |
(2012) "A new
understanding of the decoding principle on the
ribosome." Nature, 484,
256-259. doi: 10.1038/nature10913.
|
Crystal structure analysis of ribosomal decoding
(near-cognate trna-leu complex). . SNAP output
|
|
4v8c
|
ribosome-antibiotic |
X-ray (3.3 Å) |
Demeshkina N, Jenner L, Westhof E, Yusupov M,
Yusupova G |
(2012) "A new
understanding of the decoding principle on the
ribosome." Nature, 484,
256-259. doi: 10.1038/nature10913.
|
Crystal structure analysis of ribosomal decoding
(near-cognate trna-leu complex with paromomycin). .
SNAP output
|
|
4v8d
|
ribosome |
X-ray (3.0 Å) |
Demeshkina N, Jenner L, Westhof E, Yusupov M,
Yusupova G |
(2012) "A new
understanding of the decoding principle on the
ribosome." Nature, 484,
256-259. doi: 10.1038/nature10913.
|
Structure analysis of ribosomal decoding (cognate
trna-tyr complex). . SNAP output
|
|
4v8e
|
ribosome |
X-ray (3.3 Å) |
Demeshkina N, Jenner L, Westhof E, Yusupov M,
Yusupova G |
(2012) "A new
understanding of the decoding principle on the
ribosome." Nature, 484,
256-259. doi: 10.1038/nature10913.
|
Crystal structure analysis of ribosomal decoding
(near-cognate trna-tyr complex). . SNAP output
|
|
4v8f
|
ribosome |
X-ray (3.3 Å) |
Demeshkina N, Jenner L, Westhof E, Yusupov M,
Yusupova G |
(2012) "A new
understanding of the decoding principle on the
ribosome." Nature, 484,
256-259. doi: 10.1038/nature10913.
|
Crystal structure analysis of ribosomal decoding
(near-cognate trna-ttyr complex with paromomycin). .
SNAP output
|
|
4v8g
|
ribosome |
X-ray (3.0 Å) |
Polikanov YS, Blaha GM, Steitz TA |
(2012) "How
hibernation factors RMF, HPF, and YfiA turn off protein
synthesis." Science, 336,
915-918. doi: 10.1126/science.1218538.
|
Crystal structure of rmf bound to the 70s ribosome. .
SNAP output
|
|
4v8h
|
ribosome |
X-ray (3.1 Å) |
Polikanov YS, Blaha GM, Steitz TA |
(2012) "How
Hibernation Factors RMF, HPF, and YfiA Turn Off Protein
Synthesis." Science, 336,
915-918. doi: 10.1126/science.1218538.
|
Crystal structure of hpf bound to the 70s ribosome. .
SNAP output
|
|
4v8i
|
ribosome-inhibitor |
X-ray (2.7 Å) |
Polikanov YS, Blaha GM, Steitz TA |
(2012) "How
hibernation factors RMF, HPF, and YfiA turn off protein
synthesis." Science, 336,
915-918. doi: 10.1126/science.1218538.
|
Crystal structure of yfia bound to the 70s ribosome. .
SNAP output
|
|
4v8j
|
ribosome |
X-ray (3.9 Å) |
Fagan CE, Dunkle JA, Maehigashi T, Dang MN, Devaraj
A, Miles SJ, Qin D, Fredrick K, Dunham CM |
(2013) "Reorganization
of an intersubunit bridge induced by disparate 16S
ribosomal ambiguity mutations mimics an EF-Tu-bound
state." Proc.Natl.Acad.Sci.USA,
110, 9716-9721. doi: 10.1073/pnas.1301585110.
|
Crystal structure of the bacterial ribosome ram
mutation g347u. . SNAP
output
|
|
4v8m
|
ribosome |
cryo-EM (5.57 Å) |
Hashem Y, Des Georges A, Fu J, Buss SN, Jossinet F,
Jobe A, Zhang Q, Liao HY, Grassucci RA, Bajaj C, Westhof
E, Madison-Antenucci S, Frank J |
(2013) "High-Resolution
Cryo-Electron Microscopy Structure of the Trypanosoma
Brucei Ribosome." Nature,
494, 385. doi: 10.1038/NATURE11872.
|
High-resolution cryo-electron microscopy structure of
the trypanosoma brucei ribosome . SNAP output
|
|
4v8n
|
ribosome |
X-ray (3.1 Å) |
Voorhees RM, Mandal D, Neubauer C, Koehrer C,
Rajbhandary UL, Ramakrishnan V |
(2013) "The
Structural Basis for Specific Decoding of Aua by
Isoleucine tRNA on the Ribosome."
Nat.Struct.Mol.Biol., 20,
641. doi: 10.1038/NSMB.2545.
|
The crystal structure of agmatidine trna-ile2 bound to
the 70s ribosome in the a and p site. . SNAP output
|
|
4v8o
|
ribosome |
X-ray (3.8 Å) |
Jin H, Kelley AC, Ramakrishnan V |
(2011) "Crystal
Structure of the Hybrid State of Ribosome in Complex
with the Guanosine Triphosphatase Release Factor
3." Proc.Natl.Acad.Sci.USA,
108, 15798. doi: 10.1073/PNAS.1112185108.
|
Crystal structure of the hybrid state of ribosome in
complex with the guanosine triphosphatase release
factor 3 . SNAP
output
|
|
4v8p
|
ribosome |
X-ray (3.52 Å) |
Klinge S, Voigts-Hoffmann F, Leibundgut M, Arpagaus
S, Ban N |
(2011) "Crystal
Structure of the Eukaryotic 60S Ribosomal Subunit in
Complex with Initiation Factor 6."
Science, 334, 941. doi:
10.1126/SCIENCE.1211204.
|
T.thermophila 60s ribosomal subunit in complex with
initiation factor 6. . SNAP output
|
|
4v8q
|
ribosome |
X-ray (3.1 Å) |
Neubauer C, Gillet R, Kelley AC, Ramakrishnan V |
(2012) "Decoding
in the absence of a codon by tmRNA and SmpB in the
ribosome." Science, 335,
1366-1369. doi: 10.1126/science.1217039.
|
Complex of smpb, a tmrna fragment and
ef-tu-gdp-kirromycin with the 70s ribosome . SNAP output
|
|
4v8u
|
ribosome |
X-ray (3.7 Å) |
Feng S, Chen Y, Gao YG |
(2013) "Crystal
structure of 70S ribosome with both cognate tRNAs in
the E and P sites representing an authentic elongation
complex." PLoS ONE, 8,
e58829. doi: 10.1371/journal.pone.0058829.
|
Crystal structure of 70s ribosome with both cognate
trnas in the e and p sites representing an authentic
elongation complex. . SNAP output
|
|
4v8x
|
ribosome |
X-ray (3.35 Å) |
Feng S, Chen Y, Kamada K, Wang H, Tang K, Wang M, Gao
Y |
(2013) "Yoeb-Ribosome
Structure: A Canonical Rnase that Requires the Ribosome
for its Specific Activity." Nucleic Acids
Res., 41, 9549. doi: 10.1093/NAR/GKT742.
|
Structure of thermus thermophilus ribosome . SNAP output
|
|
4v8y
|
ribosome |
cryo-EM (4.3 Å) |
Fernandez IS, Bai XC, Hussain T, Kelley AC, Lorsch
JR, Ramakrishnan V, Scheres SHW |
(2013) "Molecular
architecture of a eukaryotic translational initiation
complex." Science, 342,
1240585. doi: 10.1126/science.1240585.
|
cryo-EM reconstruction of the 80s-eif5b-met-itrnamet
eukaryotic translation initiation complex . SNAP output
|
|
4v8z
|
ribosome |
cryo-EM (6.6 Å) |
Fernandez IS, Bai XC, Hussain T, Kelley AC, Lorsch
JR, Ramakrishnan V, Scheres SHW |
(2013) "Molecular
architecture of a eukaryotic translational initiation
complex." Science, 342,
1240585. doi: 10.1126/science.1240585.
|
cryo-EM reconstruction of the 80s-eif5b-met-itrnamet
eukaryotic translation initiation complex . SNAP output
|
|
4v90
|
ribosome |
X-ray (2.95 Å) |
Chen Y, Feng S, Kumar V, Ero R, Gao YG |
(2013) "Structure
of EF-G-ribosome complex in a pretranslocation
state." Nat. Struct. Mol. Biol.,
20, 1077-1084. doi: 10.1038/nsmb.2645.
|
Thermus thermophilus ribosome . SNAP output
|
|
4v91
|
ribosome |
cryo-EM (3.7 Å) |
Fernandez IS, Bai X, Murshudov G, Scheres SHW,
Ramakrishnan V |
(2014) "Initiation
of Translation by Cricket Paralysis Virus Ires Requires
its Translocation in the Ribosome."
Cell(Cambridge,Mass.), 157,
823. doi: 10.1016/J.CELL.2014.04.015.
|
Kluyveromyces lactis 80s ribosome in complex with
crpv-ires . SNAP
output
|
|
4v92
|
ribosome |
cryo-EM (3.7 Å) |
Fernandez IS, Bai X, Murshudov G, Scheres SHW,
Ramakrishnan V |
(2014) "Initiation
of Translation by Cricket Paralysis Virus Ires Requires
its Translocation in the Ribosome."
Cell(Cambridge,Mass.), 157,
823. doi: 10.1016/J.CELL.2014.04.015.
|
Kluyveromyces lactis 80s ribosome in complex with
crpv-ires . SNAP
output
|
|
4v95
|
ribosome |
X-ray (3.2 Å) |
Gagnon MG, Seetharaman SV, Bulkley D, Steitz TA |
(2012) "Structural
basis for the rescue of stalled ribosomes: structure of
YaeJ bound to the ribosome." Science,
335, 1370-1372. doi: 10.1126/science.1217443.
|
Crystal structure of yaej bound to the 70s ribosome .
SNAP output
|
|
4v97
|
ribosome |
X-ray (3.516 Å) |
Fagan CE, Dunkle JA, Maehigashi T, Dang MN, Devaraj
A, Miles SJ, Qin D, Fredrick K, Dunham CM |
(2013) "Reorganization
of an intersubunit bridge induced by disparate 16S
ribosomal ambiguity mutations mimics an EF-Tu-bound
state." Proc.Natl.Acad.Sci.USA,
110, 9716-9721. doi: 10.1073/pnas.1301585110.
|
Crystal structure of the bacterial ribosome ram
mutation g299a. . SNAP
output
|
|
4v99
|
virus-RNA |
X-ray (2.9 Å) |
Makino DL, Larson SB, McPherson A |
(2013) "The
crystallographic structure of Panicum Mosaic Virus
(PMV)." J.Struct.Biol.,
181, 37-52. doi: 10.1016/j.jsb.2012.10.012.
|
The crystallographic structure of panicum mosaic virus
. SNAP output
|
|
4v9a
|
ribosome-antibiotic |
X-ray (3.3 Å) |
Jenner L, Starosta AL, Terry DS, Mikolajka A,
Filonava L, Yusupov M, Blanchard SC, Wilson DN, Yusupova
G |
(2013) "Structural
basis for potent inhibitory activity of the antibiotic
tigecycline during protein synthesis."
Proc.Natl.Acad.Sci.USA, 110,
3812-3816. doi: 10.1073/pnas.1216691110.
|
Crystal structure of the 70s ribosome with
tetracycline. . SNAP
output
|
|
4v9b
|
ribosome-antibiotic |
X-ray (3.1 Å) |
Jenner L, Starosta AL, Terry DS, Mikolajka A,
Filonava L, Yusupov M, Blanchard SC, Wilson DN, Yusupova
G |
(2013) "Structural
basis for potent inhibitory activity of the antibiotic
tigecycline during protein synthesis."
Proc.Natl.Acad.Sci.USA, 110,
3812-3816. doi: 10.1073/pnas.1216691110.
|
Crystal structure of the 70s ribosome with tigecycline.
. SNAP output
|
|
4v9c
|
ribosome-antibiotic |
X-ray (3.3 Å) |
Wang L, Pulk A, Wasserman MR, Feldman MB, Altman RB,
Doudna Cate JH, Blanchard SC |
(2012) "Allosteric
control of the ribosome by small-molecule
antibiotics." Nat.Struct.Mol.Biol.,
19, 957-963. doi: 10.1038/nsmb.2360.
|
Allosteric control of the ribosome by small-molecule
antibiotics . SNAP
output
|
|
4v9d
|
ribosome |
X-ray (3.0 Å) |
Dunkle JA, Wang L, Feldman MB, Pulk A, Chen VB,
Kapral GJ, Noeske J, Richardson JS, Blanchard SC, Cate
JH |
(2011) "Structures
of the bacterial ribosome in classical and hybrid
states of tRNA binding." Science,
332, 981-984. doi: 10.1126/science.1202692.
|
Structures of the bacterial ribosome in classical and
hybrid states of trna binding . SNAP output
|
|
4v9e
|
viral protein-RNA |
X-ray (3.4 Å) |
Raymond DD, Piper ME, Gerrard SR, Skiniotis G, Smith
JL |
(2012) "Phleboviruses
encapsidate their genomes by sequestering RNA
bases." Proc.Natl.Acad.Sci.USA,
109, 19208-19213. doi: 10.1073/pnas.1213553109.
|
Crystal structure of rift valley fever virus
nucleocapsid protein hexamer bound to single-stranded
RNA. . SNAP output
|
|
4v9f
|
ribosome |
X-ray (2.404 Å) |
Gabdulkhakov A, Nikonov S, Garber M |
(2013) "Revisiting
the Haloarcula marismortui 50S ribosomal subunit
model." Acta Crystallogr.,Sect.D,
69, 997-1004. doi: 10.1107/S0907444913004745.
|
The re-refined crystal structure of the haloarcula
marismortui large ribosomal subunit at 2.4 angstrom
resolution: more complete structure of the l7-l12 and
l1 stalk, l5 and lx proteins . SNAP output
|
|
4v9h
|
ribosome |
X-ray (2.857 Å) |
Tourigny DS, Fernandez IS, Kelley AC, Ramakrishnan
V |
(2013) "Elongation
factor G bound to the ribosome in an intermediate state
of translocation." Science,
340, 1235490. doi: 10.1126/science.1235490.
|
Crystal structure of the ribosome bound to elongation
factor g in the guanosine triphosphatase state .
SNAP output
|
|
4v9i
|
ribosome |
X-ray (3.3 Å) |
Fernandez IS, Ng CL, Kelley AC, Wu G, Yu YT,
Ramakrishnan V |
(2013) "Unusual
base pairing during the decoding of a stop codon by the
ribosome." Nature, 500,
107-110. doi: 10.1038/nature12302.
|
Crystal structure of thermus thermophilus 70s in
complex with trnas and mrna containing a pseudouridine
in a stop codon . SNAP
output
|
|
4v9j
|
ribosome-antibiotic |
X-ray (3.86 Å) |
Zhou J, Lancaster L, Donohue JP, Noller HF |
(2013) "Crystal
structures of EF-G-ribosome complexes trapped in
intermediate states of translocation."
Science, 340, 1236086. doi:
10.1126/science.1236086.
|
70s ribosome translocation intermediate gdpnp-ii
containing elongation factor efg-gdpnp, mrna, and trna
bound in the pe*-e state. . SNAP output
|
|
4v9k
|
ribosome-antibiotic |
X-ray (3.5 Å) |
Zhou J, Lancaster L, Donohue JP, Noller HF |
(2013) "Crystal
structures of EF-G-ribosome complexes trapped in
intermediate states of translocation."
Science, 340, 1236086. doi:
10.1126/science.1236086.
|
70s ribosome translocation intermediate gdpnp-i
containing elongation factor efg-gdpnp, mrna, and trna
bound in the pe*-e state. . SNAP output
|
|
4v9l
|
ribosome-antibiotic |
X-ray (3.5 Å) |
Zhou J, Lancaster L, Donohue JP, Noller HF |
(2013) "Crystal
structures of EF-G-ribosome complexes trapped in
intermediate states of translocation."
Science, 340, 1236086. doi:
10.1126/science.1236086.
|
70s ribosome translocation intermediate fa-3.6a
containing elongation factor efg-fusidic acid-gdp,
mrna, and trna bound in the pe*-e state. . SNAP output
|
|
4v9m
|
ribosome |
X-ray (4.0 Å) |
Zhou J, Lancaster L, Donohue JP, Noller HF |
(2013) "Crystal
structures of EF-G-ribosome complexes trapped in
intermediate states of translocation."
Science, 340, 1236086. doi:
10.1126/science.1236086.
|
70s ribosome translocation intermediate fa-4.2a
containing elongation factor efg-fusidic acid-gdp,
mrna, and trna bound in the pe*-e state. . SNAP output
|
|
4v9n
|
ribosome |
X-ray (3.4 Å) |
Santos N, Zhu J, Donohue JP, Korostelev AA, Noller
HF |
(2013) "Crystal
Structure of the 70S Ribosome Bound with the Q253P
Mutant Form of Release Factor RF2."
Structure, 21, 1258-1263.
doi: 10.1016/j.str.2013.04.028.
|
Crystal structure of the 70s ribosome bound with the
q253p mutant of release factor rf2. . SNAP output
|
|
4v9o
|
ribosome-antibiotic |
X-ray (2.9 Å) |
Pulk A, Cate JH |
(2013) "Control
of ribosomal subunit rotation by elongation factor
G." Science, 340,
1235970. doi: 10.1126/science.1235970.
|
Control of ribosomal subunit rotation by elongation
factor g . SNAP
output
|
|
4v9p
|
ribosome-antibiotic |
X-ray (2.9 Å) |
Pulk A, Cate JH |
(2013) "Control
of ribosomal subunit rotation by elongation factor
G." Science, 340,
1235970. doi: 10.1126/science.1235970.
|
Control of ribosomal subunit rotation by elongation
factor g . SNAP
output
|
|
4v9q
|
ribosome |
X-ray (3.4 Å) |
Svidritskiy E, Ling C, Ermolenko DN, Korostelev
AA |
(2013) "Blasticidin
S inhibits translation by trapping deformed tRNA on the
ribosome." Proc.Natl.Acad.Sci.USA,
110, 12283-12288. doi: 10.1073/pnas.1304922110.
|
Crystal structure of blasticidin s bound to thermus
thermophilus 70s ribosome. . SNAP output
|
|
4w29
|
ribosome-antibiotic |
X-ray (3.8 Å) |
Zhou J, Lancaster L, Donohue JP, Noller HF |
(2014) "How the
ribosome hands the A-site tRNA to the P site during
EF-G-catalyzed translocation." Science,
345, 1188-1191. doi: 10.1126/science.1255030.
|
70s ribosome translocation intermediate containing
elongation factor efg-gdp-fusidic acid, mrna, and trnas
trapped in the ap-ap pe-e chimeric hybrid state. .
SNAP output
|
|
4w2e
|
ribosome |
X-ray (2.9 Å) |
Gagnon MG, Lin J, Bulkley D, Steitz TA |
(2014) "Crystal
structure of elongation factor 4 bound to a clockwise
ratcheted ribosome." Science,
345, 684-687. doi: 10.1126/science.1253525.
|
Crystal structure of elongation factor 4 (ef4-lepa)
bound to the thermus thermophilus 70s ribosome .
SNAP output
|
|
4w2f
|
ribosome-antibiotic |
X-ray (2.4 Å) |
Polikanov YS, Osterman IA, Szal T, Tashlitsky VN,
Serebryakova MV, Kusochek P, Bulkley D, Malanicheva IA,
Efimenko TA, Efremenkova OV, Konevega AL, Shaw KJ,
Bogdanov AA, Rodnina MV, Dontsova OA, Mankin AS, Steitz
TA, Sergiev PV |
(2014) "Amicoumacin
a inhibits translation by stabilizing mRNA interaction
with the ribosome." Mol.Cell,
56, 531-540. doi: 10.1016/j.molcel.2014.09.020.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with amicoumacin, mrna and three
deacylated trnas in the a, p and e sites . SNAP output
|
|
4w2g
|
ribosome-antibiotic |
X-ray (2.55 Å) |
Polikanov YS, Osterman IA, Szal T, Tashlitsky VN,
Serebryakova MV, Kusochek P, Bulkley D, Malanicheva IA,
Efimenko TA, Efremenkova OV, Konevega AL, Shaw KJ,
Bogdanov AA, Rodnina MV, Dontsova OA, Mankin AS, Steitz
TA, Sergiev PV |
(2014) "Amicoumacin
a inhibits translation by stabilizing mRNA interaction
with the ribosome." Mol.Cell,
56, 531-540. doi: 10.1016/j.molcel.2014.09.020.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with pactamycin (soaked), mrna and
three deacylated trnas in the a, p and e sites .
SNAP output
|
|
4w2h
|
ribosome-antibiotic |
X-ray (2.7 Å) |
Polikanov YS, Osterman IA, Szal T, Tashlitsky VN,
Serebryakova MV, Kusochek P, Bulkley D, Malanicheva IA,
Efimenko TA, Efremenkova OV, Konevega AL, Shaw KJ,
Bogdanov AA, Rodnina MV, Dontsova OA, Mankin AS, Steitz
TA, Sergiev PV |
(2014) "Amicoumacin
a inhibits translation by stabilizing mRNA interaction
with the ribosome." Mol.Cell,
56, 531-540. doi: 10.1016/j.molcel.2014.09.020.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with pactamycin (co-crystallized),
mrna and deacylated trna in the p site . SNAP output
|
|
4w2i
|
ribosome-antibiotic |
X-ray (2.7 Å) |
Polikanov YS, Szal T, Jiang F, Gupta P, Matsuda R,
Shiozuka M, Steitz TA, Vazquez-Laslop N, Mankin AS |
(2014) "Negamycin
Interferes with Decoding and Translocation by
Simultaneous Interaction with rRNA and tRNA."
Mol.Cell, 56, 541-550. doi:
10.1016/j.molcel.2014.09.021.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with negamycin, mrna and three
deacylated trnas in the a, p and e sites . SNAP output
|
|
4w4g
|
ribosome |
X-ray (3.3 Å) |
Schureck MA, Dunkle JA, Maehigashi T, Miles SJ,
Dunham CM |
(2015) "Defining
the mRNA recognition signature of a bacterial toxin
protein." Proc.Natl.Acad.Sci.USA,
112, 13862-13867. doi: 10.1073/pnas.1512959112.
|
Postcleavage state of 70s bound to higb toxin and aaa
(lysine) codon . SNAP
output
|
|
4w5n
|
hydrolase-RNA |
X-ray (2.9 Å) |
Schirle NT, Sheu-Gruttadauria J, MacRae IJ |
(2014) "Gene
regulation. Structural basis for microRNA
targeting." Science, 346,
608-613. doi: 10.1126/science.1258040.
|
The crystal structure of human argonaute2 bound to a
defined guide RNA . SNAP
output
|
|
4w5o
|
hydrolase-RNA |
X-ray (1.802 Å) |
Schirle NT, Sheu-Gruttadauria J, MacRae IJ |
(2014) "Gene
regulation. Structural basis for microRNA
targeting." Science, 346,
608-613. doi: 10.1126/science.1258040.
|
The crystal structure of human argonaute2 bound to a
guide and target RNA containing seed pairing from 2-9 .
SNAP output
|
|
4w5q
|
hydrolase-RNA |
X-ray (3.101 Å) |
Schirle NT, Sheu-Gruttadauria J, MacRae IJ |
(2014) "Gene
regulation. Structural basis for microRNA
targeting." Science, 346,
608-613. doi: 10.1126/science.1258040.
|
The crystal structure of human argonaute2 bound to a
guide and target RNA containing seed pairing from 2-8 .
SNAP output
|
|
4w5r
|
hydrolase-RNA |
X-ray (2.5 Å) |
Schirle NT, Sheu-Gruttadauria J, MacRae IJ |
(2014) "Gene
regulation. Structural basis for microRNA
targeting." Science, 346,
608-613. doi: 10.1126/science.1258040.
|
The crystal structure of human argonaute2 bound to a
guide and target RNA containing seed pairing from 2-8
(long target) . SNAP
output
|
|
4w5t
|
hydrolase-RNA |
X-ray (2.5 Å) |
Schirle NT, Sheu-Gruttadauria J, MacRae IJ |
(2014) "Gene
regulation. Structural basis for microRNA
targeting." Science, 346,
608-613. doi: 10.1126/science.1258040.
|
The crystal structure of human argonaute2 bound to a
guide and target RNA containing seed pairing from 2-7 .
SNAP output
|
|
4w90
|
RNA binding protein-RNA |
X-ray (3.118 Å) |
Jones CP, Ferre-D'Amare AR |
(2014) "Crystal
structure of a c-di-AMP riboswitch reveals an
internally pseudo-dimeric RNA." Embo J.,
33, 2692-2703. doi: 10.15252/embj.201489209.
|
Crystal structure of bacillus subtilis cyclic-di-amp
riboswitch ydao . SNAP
output
|
|
4w92
|
RNA binding protein-RNA |
X-ray (3.209 Å) |
Jones CP, Ferre-D'Amare AR |
(2014) "Crystal
structure of a c-di-AMP riboswitch reveals an
internally pseudo-dimeric RNA." Embo J.,
33, 2692-2703. doi: 10.15252/embj.201489209.
|
Crystal structure of bacillus subtilis cyclic-di-amp
riboswitch ydao . SNAP
output
|
|
4wc2
|
transferase-RNA |
X-ray (2.8 Å) |
Yamashita S, Martinez A, Tomita K |
(2015) "Measurement
of Acceptor-T Psi C Helix Length of tRNA for Terminal
A76-Addition by A-Adding Enzyme."
Structure, 23, 830-842. doi:
10.1016/j.str.2015.03.013.
|
Crystal structure of trna nucleotidyltransferase
complexed with a primer trna and an incoming atp analog
. SNAP output
|
|
4wc3
|
transferase-RNA |
X-ray (3.1 Å) |
Yamashita S, Martinez A, Tomita K |
(2015) "Measurement
of Acceptor-T Psi C Helix Length of tRNA for Terminal
A76-Addition by A-Adding Enzyme."
Structure, 23, 830-842. doi:
10.1016/j.str.2015.03.013.
|
Structure of trna-processing enzyme complex 1 .
SNAP output
|
|
4wc4
|
transferase-RNA |
X-ray (3.501 Å) |
Yamashita S, Martinez A, Tomita K |
(2015) "Measurement
of Acceptor-T Psi C Helix Length of tRNA for Terminal
A76-Addition by A-Adding Enzyme."
Structure, 23, 830-842. doi:
10.1016/j.str.2015.03.013.
|
Trna-processing enzyme complex 2 . SNAP output
|
|
4wc5
|
transferase-RNA |
X-ray (3.41 Å) |
Yamashita S, Martinez A, Tomita K |
(2015) "Measurement
of Acceptor-T Psi C Helix Length of tRNA for Terminal
A76-Addition by A-Adding Enzyme."
Structure, 23, 830-842. doi:
10.1016/j.str.2015.03.013.
|
Structure of trna-processing enzyme complex 3 .
SNAP output
|
|
4wc6
|
transferase-RNA |
X-ray (3.41 Å) |
Yamashita S, Martinez A, Tomita K |
(2015) "Measurement
of Acceptor-T Psi C Helix Length of tRNA for Terminal
A76-Addition by A-Adding Enzyme."
Structure, 23, 830-842. doi:
10.1016/j.str.2015.03.013.
|
Structure of trna-processing enzyme complex 4 .
SNAP output
|
|
4wc7
|
transferase-RNA |
X-ray (3.102 Å) |
Yamashita S, Martinez A, Tomita K |
(2015) "Measurement
of Acceptor-T Psi C Helix Length of tRNA for Terminal
A76-Addition by A-Adding Enzyme."
Structure, 23, 830-842. doi:
10.1016/j.str.2015.03.013.
|
Structure of trna-processing enzyme complex 5 .
SNAP output
|
|
4wce
|
ribosome |
X-ray (3.526 Å) |
Eyal Z, Matzov D, Krupkin M, Wekselman I, Paukner S,
Zimmerman E, Rozenberg H, Bashan A, Yonath A |
(2015) "Structural
insights into species-specific features of the ribosome
from the pathogen Staphylococcus aureus."
Proc.Natl.Acad.Sci.USA, 112,
E5805-E5814. doi: 10.1073/pnas.1517952112.
|
The crystal structure of the large ribosomal subunit of
staphylococcus aureus . SNAP output
|
|
4wf1
|
ribosome-antibiotic |
X-ray (3.09 Å) |
Olivier NB, Altman RB, Noeske J, Basarab GS, Code E,
Ferguson AD, Gao N, Huang J, Juette MF, Livchak S, Miller
MD, Prince DB, Cate JH, Buurman ET, Blanchard SC |
(2014) "Negamycin
induces translational stalling and miscoding by binding
to the small subunit head domain of the Escherichia
coli ribosome." Proc.Natl.Acad.Sci.USA,
111, 16274-16279. doi: 10.1073/pnas.1414401111.
|
Crystal structure of the e. coli ribosome bound to
negamycin. . SNAP
output
|
|
4wf9
|
ribosome |
X-ray (3.427 Å) |
Eyal Z, Matzov D, Krupkin M, Wekselman I, Paukner S,
Zimmerman E, Rozenberg H, Bashan A, Yonath A |
(2015) "Structural
insights into species-specific features of the ribosome
from the pathogen Staphylococcus aureus."
Proc.Natl.Acad.Sci.USA, 112,
E5805-E5814. doi: 10.1073/pnas.1517952112.
|
The crystal structure of the large ribosomal subunit of
staphylococcus aureus in complex with telithromycin .
SNAP output
|
|
4wfa
|
ribosome |
X-ray (3.392 Å) |
Eyal Z, Matzov D, Krupkin M, Wekselman I, Paukner S,
Zimmerman E, Rozenberg H, Bashan A, Yonath A |
(2015) "Structural
insights into species-specific features of the ribosome
from the pathogen Staphylococcus aureus."
Proc.Natl.Acad.Sci.USA, 112,
E5805-E5814. doi: 10.1073/pnas.1517952112.
|
The crystal structure of the large ribosomal subunit of
staphylococcus aureus in complex with linezolid .
SNAP output
|
|
4wfb
|
ribosome |
X-ray (3.43 Å) |
Eyal Z, Matzov D, Krupkin M, Wekselman I, Paukner S,
Zimmerman E, Rozenberg H, Bashan A, Yonath A |
(2015) "Structural
insights into species-specific features of the ribosome
from the pathogen Staphylococcus aureus."
Proc.Natl.Acad.Sci.USA, 112,
E5805-E5814. doi: 10.1073/pnas.1517952112.
|
The crystal structure of the large ribosomal subunit of
staphylococcus aureus in complex with bc-3205 .
SNAP output
|
|
4wfn
|
ribosome |
X-ray (3.54 Å) |
Wekselman I, Zimmerman E, Davidovich C, Belousoff M,
Matzov D, Krupkin M, Rozenberg H, Bashan A, Friedlander
G, Kjeldgaard J, Ingmer H, Lindahl L, Zengel JM, Yonath
A |
(2017) "The
Ribosomal Protein uL22 Modulates the Shape of the
Protein Exit Tunnel." Structure,
25, 1233-1241.e3. doi: 10.1016/j.str.2017.06.004.
|
Crystal structure of the large ribosomal subunit (50s)
of deinococcus radiodurans containing a three residue
insertion in l22 in complex with erythromycin .
SNAP output
|
|
4wj3
|
ligase-RNA |
X-ray (3.705 Å) |
Suzuki T, Nakamura A, Kato K, Soll D, Tanaka I,
Sheppard K, Yao M |
(2015) "Structure
of the Pseudomonas aeruginosa transamidosome reveals
unique aspects of bacterial tRNA-dependent asparagine
biosynthesis." Proc.Natl.Acad.Sci.USA,
112, 382-387. doi: 10.1073/pnas.1423314112.
|
Crystal structure of the asparagine transamidosome from
pseudomonas aeruginosa . SNAP output
|
|
4wj4
|
ligase-RNA |
X-ray (3.294 Å) |
Suzuki T, Nakamura A, Kato K, Soll D, Tanaka I,
Sheppard K, Yao M |
(2015) "Structure
of the Pseudomonas aeruginosa transamidosome reveals
unique aspects of bacterial tRNA-dependent asparagine
biosynthesis." Proc.Natl.Acad.Sci.USA,
112, 382-387. doi: 10.1073/pnas.1423314112.
|
Crystal structure of non-discriminating aspartyl-trna
synthetase from pseudomonas aeruginosa complexed with
trna(asn) and aspartic acid . SNAP output
|
|
4woi
|
ribosome |
X-ray (3.0 Å) |
Wasserman MR, Pulk A, Zhou Z, Altman RB, Zinder JC,
Green KD, Garneau-Tsodikova S, Doudna Cate JH, Blanchard
SC |
(2015) "Chemically
related 4,5-linked aminoglycoside antibiotics drive
subunit rotation in opposite directions." Nat
Commun, 6, 7896. doi: 10.1038/ncomms8896.
|
4,5-linked aminoglycoside antibiotics regulate the
bacterial ribosome by targeting dynamic conformational
processes within intersubunit bridge b2 . SNAP output
|
|
4wpo
|
ribosome |
X-ray (2.8 Å) |
Lin J, Gagnon MG, Bulkley D, Steitz TA |
(2015) "Conformational
Changes of Elongation Factor G on the Ribosome during
tRNA Translocation." Cell,
160, 219-227. doi: 10.1016/j.cell.2014.11.049.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with elongation factor g in the
pre-translocational state . SNAP output
|
|
4wq1
|
ribosome |
X-ray (3.1 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-tyr and mrna with c-a
mismatch in the first position in the a-site. .
SNAP output
|
|
4wqf
|
ribosome |
X-ray (2.8 Å) |
Lin J, Gagnon MG, Bulkley D, Steitz TA |
(2015) "Conformational
Changes of Elongation Factor G on the Ribosome during
tRNA Translocation." Cell,
160, 219-227. doi: 10.1016/j.cell.2014.11.049.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with elongation factor g and
fusidic acid in the post-translocational state .
SNAP output
|
|
4wqr
|
ribosome |
X-ray (3.15 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-phe and mrna with c-a
mismatch in the first position in the a-site. .
SNAP output
|
|
4wqu
|
ribosome-antibiotic |
X-ray (2.8 Å) |
Lin J, Gagnon MG, Bulkley D, Steitz TA |
(2015) "Conformational
Changes of Elongation Factor G on the Ribosome during
tRNA Translocation." Cell,
160, 219-227. doi: 10.1016/j.cell.2014.11.049.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with elongation factor g trapped by
the antibiotic dityromycin . SNAP output
|
|
4wqy
|
ribosome |
X-ray (2.8 Å) |
Lin J, Gagnon MG, Bulkley D, Steitz TA |
(2015) "Conformational
Changes of Elongation Factor G on the Ribosome during
tRNA Translocation." Cell,
160, 219-227. doi: 10.1016/j.cell.2014.11.049.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with elongation factor g in the
post-translocational state (without fusitic acid) .
SNAP output
|
|
4wr6
|
ribosome |
X-ray (3.05 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-tyr and mrna with a-a
mismatch in the first position in the a-site. .
SNAP output
|
|
4wra
|
ribosome |
X-ray (3.05 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-tyr and mrna with a-a
mismatch in the first position in the a-site and with
antibiotic paromomycin. . SNAP output
|
|
4wro
|
ribosome |
X-ray (3.05 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-phe and mrna with c-a
mismatch in the second position in the a-site .
SNAP output
|
|
4wrt
|
transferase-RNA |
X-ray (2.7 Å) |
Reich S, Guilligay D, Pflug A, Malet H, Berger I,
Crepin T, Hart D, Lunardi T, Nanao M, Ruigrok RW, Cusack
S |
(2014) "Structural
insight into cap-snatching and RNA synthesis by
influenza polymerase." Nature,
516, 361-366. doi: 10.1038/nature14009.
|
Crystal structure of influenza b polymerase with bound
vrna promoter (form flub2) . SNAP output
|
|
4wsa
|
transferase-RNA |
X-ray (3.4 Å) |
Reich S, Guilligay D, Pflug A, Malet H, Berger I,
Crepin T, Hart D, Lunardi T, Nanao M, Ruigrok RW, Cusack
S |
(2014) "Structural
insight into cap-snatching and RNA synthesis by
influenza polymerase." Nature,
516, 361-366. doi: 10.1038/nature14009.
|
Crystal structure of influenza b polymerase bound to
the vrna promoter (flub1 form) . SNAP output
|
|
4wsb
|
transferase-RNA |
X-ray (2.65 Å) |
Reich S, Guilligay D, Pflug A, Malet H, Berger I,
Crepin T, Hart D, Lunardi T, Nanao M, Ruigrok RW, Cusack
S |
(2014) "Structural
insight into cap-snatching and RNA synthesis by
influenza polymerase." Nature,
516, 361-366. doi: 10.1038/nature14009.
|
Bat influenza a polymerase with bound vrna promoter .
SNAP output
|
|
4wsd
|
ribosome |
X-ray (2.95 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-phe and mrna with c-a
mismatch in the second position in the a-site and with
antibiotic paromomycin. . SNAP output
|
|
4wsm
|
ribosome |
X-ray (3.3 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-leu and mrna with g-u
mismatch in the first position in the a- and p-sites .
SNAP output
|
|
4wt1
|
ribosome |
X-ray (3.05 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-phe and mrna with a-a
mismatch in the second position in the a-site .
SNAP output
|
|
4wta
|
transferase-RNA |
X-ray (2.8 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations and delta8
beta hairpin loop deletion in complex with udp, mn2+
and symmetrical primer template 5'-caaaauuu . SNAP output
|
|
4wtc
|
transferase-RNA |
X-ray (2.75 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations and delta8
beta hairpin loop deletion in complex with cdp, mn2+
and symmetrical primer template 5'-agaaauuu . SNAP output
|
|
4wtd
|
transferase-RNA |
X-ray (2.7 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations and delta8
beta hairpin loop deletion in complex with adp, mn2+
and symmetrical primer template 5'-auaaauuu . SNAP output
|
|
4wte
|
transferase-RNA |
X-ray (2.9 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations and delta8
beta hairpin loop deletion in complex with gdp, mn2+
and symmetrical primer template 5'-acaaauuu . SNAP output
|
|
4wtf
|
transferase-RNA |
X-ray (2.65 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations and delta8
beta hairpin loop deletion in complex with gs-639475,
mn2+ and symmetrical primer template 5'-caaaauuu .
SNAP output
|
|
4wti
|
transferase-RNA |
X-ray (2.8 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations in complex
with RNA template 5'-acgg, RNA primer 5'-pcc, mn2+, and
gdp . SNAP output
|
|
4wtj
|
transferase-RNA |
X-ray (2.2 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations in complex
with RNA template 5'-aucc, RNA primer 5'-pgg, mn2+, and
adp . SNAP output
|
|
4wtk
|
transferase-RNA |
X-ray (2.5 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations in complex
with RNA template 5'-agcc, RNA primer 5'-pgg, mn2+, and
cdp . SNAP output
|
|
4wtl
|
transferase-RNA |
X-ray (2.0 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations in complex
with RNA template 5'-uacc, RNA primer 5'-pgg, mn2+, and
udp . SNAP output
|
|
4wtm
|
transferase-RNA |
X-ray (2.15 Å) |
Appleby TC, Perry JK, Murakami E, Barauskas O, Feng
J, Cho A, Fox D, Wetmore DR, McGrath ME, Ray AS, Sofia
MJ, Swaminathan S, Edwards TE |
(2015) "Structural
basis for RNA replication by the hepatitis C virus
polymerase." Science,
347, 771-775. doi: 10.1126/science.1259210.
|
Crystal structure of hcv ns5b genotype 2a jfh-1 isolate
with s15g e86q e87q c223h v321i mutations in complex
with RNA template 5'-uagg, RNA primer 5'-pcc, mn2+, and
udp . SNAP output
|
|
4wu1
|
ribosome |
X-ray (3.2 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-tyr and mrna with g-u
mismatch in the second position in the p-site .
SNAP output
|
|
4www
|
ribosome-antibiotic |
X-ray (3.1 Å) |
Llano-Sotelo B, Dunkle J, Klepacki D, Zhang W,
Fernandes P, Cate JH, Mankin AS |
(2010) "Binding
and action of CEM-101, a new fluoroketolide antibiotic
that inhibits protein synthesis." Antimicrob.
Agents Chemother., 54, 4961-4970.
doi: 10.1128/AAC.00860-10.
|
Crystal structure of the e. coli ribosome bound to
cem-101 . SNAP
output
|
|
4wzd
|
ribosome |
X-ray (3.1 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with cognate trna-tyr in the
p-site . SNAP output
|
|
4wzj
|
splicing |
X-ray (3.6 Å) |
Leung AK, Nagai K, Li J |
(2011) "Structure
of the spliceosomal U4 snRNP core domain and its
implication for snRNP biogenesis." Nature,
473, 536-539. doi: 10.1038/nature09956.
|
Spliceosomal u4 snrnp core domain . SNAP output
|
|
4wzm
|
transferase |
X-ray (2.52 Å) |
Ferrer-Orta C, de la Higuera I, Caridi F,
Sanchez-Aparicio MT, Moreno E, Perales C, Singh K,
Sarafianos SG, Sobrino F, Domingo E, Verdaguer N |
(2015) "Multifunctionality
of a picornavirus polymerase domain: nuclear
localization signal and nucleotide recognition."
J.Virol., 89, 6848-6859. doi:
10.1128/JVI.03283-14.
|
Mutant k18e of RNA dependent RNA polymerase from
foot-and-mouth disease virus complexed with RNA .
SNAP output
|
|
4wzo
|
ribosome |
X-ray (3.3 Å) |
Rozov A, Demeshkina N, Westhof E, Yusupov M, Yusupova
G |
(2015) "Structural
insights into the translational infidelity
mechanism." Nat Commun,
6, 7251. doi: 10.1038/ncomms8251.
|
Complex of 70s ribosome with trna-fmet and mrna .
SNAP output
|
|
4wzq
|
transferase |
X-ray (2.8 Å) |
Ferrer-Orta C, de la Higuera I, Caridi F,
Sanchez-Aparicio MT, Moreno E, Perales C, Singh K,
Sarafianos SG, Sobrino F, Domingo E, Verdaguer N |
(2015) "Multifunctionality
of a picornavirus polymerase domain: nuclear
localization signal and nucleotide recognition."
J.Virol., 89, 6848-6859. doi:
10.1128/JVI.03283-14.
|
Mutant k20e of RNA dependent RNA polymerase 3d from
foot-and-mouth disease virus complexed with RNA .
SNAP output
|
|
4x0a
|
transferase-RNA |
X-ray (3.505 Å) |
Yamashita S, Martinez A, Tomita K |
(2015) "Measurement
of Acceptor-T Psi C Helix Length of tRNA for Terminal
A76-Addition by A-Adding Enzyme."
Structure, 23, 830-842. doi:
10.1016/j.str.2015.03.013.
|
Structure of trna-processing enzyme complex 6 .
SNAP output
|
|
4x0b
|
transferase-RNA |
X-ray (3.2 Å) |
Yamashita S, Martinez A, Tomita K |
(2015) "Measurement
of Acceptor-T Psi C Helix Length of tRNA for Terminal
A76-Addition by A-Adding Enzyme."
Structure, 23, 830-842. doi:
10.1016/j.str.2015.03.013.
|
Structure of trna-processing enzyme complex 7 .
SNAP output
|
|
4x2b
|
transferase |
X-ray (2.94 Å) |
Ferrer-Orta C, de la Higuera I, Caridi F,
Sanchez-Aparicio MT, Moreno E, Perales C, Singh K,
Sarafianos SG, Sobrino F, Domingo E, Verdaguer N |
(2015) "Multifunctionality
of a picornavirus polymerase domain: nuclear
localization signal and nucleotide recognition."
J.Virol., 89, 6848-6859. doi:
10.1128/JVI.03283-14.
|
K20a RNA dependent RNA polymerase mutant from
foot-and-mouth disease virus complexed with an RNA .
SNAP output
|
|
4x4n
|
transferase-RNA |
X-ray (2.953 Å) |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor
L |
(2015) "On-Enzyme
Refolding Permits Small RNA and tRNA Surveillance by
the CCA-Adding Enzyme." Cell,
160, 644-658. doi: 10.1016/j.cell.2015.01.005.
|
Crystal structure of the a.fulgidus cca-adding enzyme
in complex with a g70a arginyl-trna minihelix .
SNAP output
|
|
4x4o
|
RNA binding protein |
X-ray (3.201 Å) |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor
L |
(2015) "On-Enzyme
Refolding Permits Small RNA and tRNA Surveillance by
the CCA-Adding Enzyme." Cell,
160, 644-658. doi: 10.1016/j.cell.2015.01.005.
|
Crystal structure of the a.fulgidus cca-adding enzyme
in complex with a g70a arginyl-trna minihelix and ctp .
SNAP output
|
|
4x4p
|
RNA binding protein |
X-ray (3.0 Å) |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor
L |
(2015) "On-Enzyme
Refolding Permits Small RNA and tRNA Surveillance by
the CCA-Adding Enzyme." Cell,
160, 644-658. doi: 10.1016/j.cell.2015.01.005.
|
Crystal structure of the a.fulgidus cca-adding enzyme
in complex with a g70a arginyl-trna minihelix ending in
ccac . SNAP output
|
|
4x4q
|
RNA binding protein |
X-ray (3.15 Å) |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor
L |
(2015) "On-Enzyme
Refolding Permits Small RNA and tRNA Surveillance by
the CCA-Adding Enzyme." Cell,
160, 644-658. doi: 10.1016/j.cell.2015.01.005.
|
Crystal structure of the a.fulgidus cca-adding enzyme
in complex with a g70a arginyl-trna minihelix ending in
ccac and ctp . SNAP
output
|
|
4x4r
|
RNA binding protein |
X-ray (3.202 Å) |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor
L |
(2015) "On-Enzyme
Refolding Permits Small RNA and tRNA Surveillance by
the CCA-Adding Enzyme." Cell,
160, 644-658. doi: 10.1016/j.cell.2015.01.005.
|
Crystal structure of the a.fulgidus cca-adding enzyme
in complex with a g70a arginyl-trna minihelix ending in
ccacc and ampcpp . SNAP
output
|
|
4x4s
|
RNA binding protein |
X-ray (3.25 Å) |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor
L |
(2015) "On-enzyme
refolding permits small RNA and tRNA surveillance by
the CCA-adding enzyme." Cell,
160, 644-658. doi: 10.1016/j.cell.2015.01.005.
|
Crystal structure of the a.fulgidus cca-adding enzyme
in complex with a g70a arginyl-trna minihelix ending in
ccacc and ctp . SNAP
output
|
|
4x4t
|
transferase-RNA |
X-ray (2.5 Å) |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor
L |
(2015) "On-Enzyme
Refolding Permits Small RNA and tRNA Surveillance by
the CCA-Adding Enzyme." Cell,
160, 644-658. doi: 10.1016/j.cell.2015.01.005.
|
Crystal structure of the a.fulgidus cca-adding enzyme
in complex with a g70a arginyl-trna minihelix ending in
ccacca . SNAP output
|
|
4x4u
|
RNA binding protein |
X-ray (2.7 Å) |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor
L |
(2015) "On-Enzyme
Refolding Permits Small RNA and tRNA Surveillance by
the CCA-Adding Enzyme." Cell,
160, 644-658. doi: 10.1016/j.cell.2015.01.005.
|
Crystal structure of the a.fulgidus cca-adding enzyme
in complex with a human menbeta minihelix ending in
ccacc . SNAP output
|
|
4x4v
|
RNA binding protein |
X-ray (2.6 Å) |
Kuhn CD, Wilusz JE, Zheng Y, Beal PA, Joshua-Tor
L |
(2015) "On-Enzyme
Refolding Permits Small RNA and tRNA Surveillance by
the CCA-Adding Enzyme." Cell,
160, 644-658. doi: 10.1016/j.cell.2015.01.005.
|
Crystal structure of the a.fulgidus cca-adding enzyme
in complex with a human menbeta minihelix ending in
ccacc and ampcpp . SNAP
output
|
|
4x62
|
ribosome-antibiotic |
X-ray (3.45 Å) |
Choi J, Ieong KW, Demirci H, Chen J, Petrov A,
Prabhakar A, O'Leary SE, Dominissini D, Rechavi G, Soltis
SM, Ehrenberg M, Puglisi JD |
(2016) "N(6)-methyladenosine
in mRNA disrupts tRNA selection and
translation-elongation dynamics."
Nat.Struct.Mol.Biol., 23,
110-115. doi: 10.1038/nsmb.3148.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4x64
|
ribosome-antibiotic |
X-ray (3.35 Å) |
Choi J, Ieong KW, Demirci H, Chen J, Petrov A,
Prabhakar A, O'Leary SE, Dominissini D, Rechavi G, Soltis
SM, Ehrenberg M, Puglisi JD |
(2016) "N(6)-methyladenosine
in mRNA disrupts tRNA selection and
translation-elongation dynamics."
Nat.Struct.Mol.Biol., 23,
110-115. doi: 10.1038/nsmb.3148.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4x65
|
ribosome-antibiotic |
X-ray (3.345 Å) |
Choi J, Ieong KW, Demirci H, Chen J, Petrov A,
Prabhakar A, O'Leary SE, Dominissini D, Rechavi G, Soltis
SM, Ehrenberg M, Puglisi JD |
(2016) "N(6)-methyladenosine
in mRNA disrupts tRNA selection and
translation-elongation dynamics."
Nat.Struct.Mol.Biol., 23,
110-115. doi: 10.1038/nsmb.3148.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4x66
|
ribosome-antibiotic |
X-ray (3.446 Å) |
Choi J, Ieong KW, Demirci H, Chen J, Petrov A,
Prabhakar A, O'Leary SE, Dominissini D, Rechavi G, Soltis
SM, Ehrenberg M, Puglisi JD |
(2016) "N(6)-methyladenosine
in mRNA disrupts tRNA selection and
translation-elongation dynamics."
Nat.Struct.Mol.Biol., 23,
110-115. doi: 10.1038/nsmb.3148.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
4xbf
|
oxidoreductase-transcription-RNA |
X-ray (2.803 Å) |
Hirschi A, Martin WJ, Luka Z, Loukachevitch LV,
Reiter NJ |
(2016) "G-quadruplex
RNA binding and recognition by the lysine-specific
histone demethylase-1 enzyme." RNA,
22, 1250-1260. doi: 10.1261/rna.057265.116.
|
Structure of lsd1:corest in complex with ssrna .
SNAP output
|
|
4xco
|
RNA binding protein |
X-ray (2.9 Å) |
Hainzl T, Sauer-Eriksson AE |
(2015) "Signal-sequence
induced conformational changes in the signal
recognition particle." Nat Commun,
6, 7163. doi: 10.1038/ncomms8163.
|
Signal-sequence induced conformational changes in the
signal recognition particle . SNAP output
|
|
4xej
|
ribosome |
X-ray (3.8 Å) |
Colussi TM, Costantino DA, Zhu J, Donohue JP,
Korostelev AA, Jaafar ZA, Plank TD, Noller HF, Kieft
JS |
(2015) "Initiation
of translation in bacteria by a structured eukaryotic
IRES RNA." Nature, 519,
110-113. doi: 10.1038/nature14219.
|
Ires bound to bacterial ribosome . SNAP output
|
|
4xjn
|
viral protein-RNA |
X-ray (3.11 Å) |
Alayyoubi M, Leser GP, Kors CA, Lamb RA |
(2015) "Structure
of the paramyxovirus parainfluenza virus 5
nucleoprotein-RNA complex."
Proc.Natl.Acad.Sci.USA, 112,
E1792-E1799. doi: 10.1073/pnas.1503941112.
|
Structure of the parainfluenza virus 5 nucleocapsid-RNA
complex: an insight into paramyxovirus polymerase
activity . SNAP
output
|
|
4xww
|
RNA binding protein-RNA |
X-ray (1.7 Å) |
Zhao Y, Lu M, Zhang H, Hu J, Zhou C, Xu Q, Shah AMUH,
Xu H, Wang L, Hua Y |
(2015) "Structural
insights into catalysis and dimerization enhanced
exonuclease activity of RNase J." Nucleic Acids
Res., 43, 5550-5559. doi:
10.1093/nar/gkv444.
|
Crystal structure of rnase j complexed with RNA .
SNAP output
|
|
4y4o
|
ribosome |
X-ray (2.3 Å) |
Polikanov YS, Melnikov SV, Soll D, Steitz TA |
(2015) "Structural
insights into the role of rRNA modifications in protein
synthesis and ribosome assembly."
Nat.Struct.Mol.Biol., 22,
342-344. doi: 10.1038/nsmb.2992.
|
Crystal structure of the thermus thermophilus 70s
ribosome with rrna modifications and bound to protein y
(yfia) at 2.3a resolution . SNAP output
|
|
4y4p
|
ribosome |
X-ray (2.5 Å) |
Polikanov YS, Melnikov SV, Soll D, Steitz TA |
(2015) "Structural
insights into the role of rRNA modifications in protein
synthesis and ribosome assembly."
Nat.Struct.Mol.Biol., 22,
342-344. doi: 10.1038/nsmb.2992.
|
Crystal structure of the thermus thermophilus 70s
ribosome with rrna modifications and bound to mrna and
a-, p- and e-site trnas at 2.5a resolution . SNAP output
|
|
4y91
|
RNA binding protein-RNA |
X-ray (2.656 Å) |
Patterson J, Randolph PS, Mura C |
"Crystal Structure of a Thermotoga maritima Hfq
homolog." |
Crystal structure of a thermotoga maritima hfq homolog
. SNAP output
|
|
4yb1
|
RNA-RNA binding protein |
X-ray (2.081 Å) |
Ren A, Wang XC, Kellenberger CA, Rajashankar KR,
Jones RA, Hammond MC, Patel DJ |
(2015) "Structural
Basis for Molecular Discrimination by a 3',3'-cGAMP
Sensing Riboswitch." Cell Rep,
11, 1-12. doi: 10.1016/j.celrep.2015.03.004.
|
20a mutant c-di-gmp vc2 riboswitch bound with
3',3'-cgamp . SNAP
output
|
|
4ybb
|
ribosome |
X-ray (2.1 Å) |
Noeske J, Wasserman MR, Terry DS, Altman RB,
Blanchard SC, Cate JH |
(2015) "High-resolution
structure of the Escherichia coli ribosome."
Nat.Struct.Mol.Biol., 22,
336-341. doi: 10.1038/nsmb.2994.
|
High-resolution structure of the escherichia coli
ribosome . SNAP
output
|
|
4yco
|
oxidoreductase |
X-ray (2.1 Å) |
Byrne RT, Jenkins HT, Peters DT, Whelan F, Stowell J,
Aziz N, Kasatsky P, Rodnina MV, Koonin EV, Konevega AL,
Antson AA |
(2015) "Major
reorientation of tRNA substrates defines specificity of
dihydrouridine synthases."
Proc.Natl.Acad.Sci.USA, 112,
6033-6037. doi: 10.1073/pnas.1500161112.
|
E. coli dihydrouridine synthase c (dusc) in complex
with trnaphe . SNAP
output
|
|
4yhh
|
ribosome |
X-ray (3.417 Å) |
Schedlbauer A, Kaminishi T, Ochoa-Lizarralde B,
Dhimole N, Zhou S, Lopez-Alonso JP, Connell SR, Fucini
P |
(2015) "Structural
characterization of an alternative mode of tigecycline
binding to the bacterial ribosome."
Antimicrob.Agents Chemother.,
59, 2849-2854. doi: 10.1128/AAC.04895-14.
|
Crystal structure of the 30s ribosomal subunit from
thermus thermophilus in complex with tigecycline .
SNAP output
|
|
4yhw
|
splicing |
X-ray (3.25 Å) |
Liu S, Mozaffari-Jovin S, Wollenhaupt J, Santos KF,
Theuser M, Dunin-Horkawicz S, Fabrizio P, Bujnicki JM,
Luhrmann R, Wahl MC |
(2015) "A
composite double-/single-stranded RNA-binding region in
protein Prp3 supports tri-snRNP stability and
splicing." Elife, 4,
e07320. doi: 10.7554/eLife.07320.
|
Yeast prp3 (296-469) in complex with fragment of u4-u6
di-snrna . SNAP
output
|
|
4yoe
|
RNA binding protein-RNA |
X-ray (1.92 Å) |
Morgan CE, Meagher JL, Levengood JD, Delproposto J,
Rollins C, Stuckey JA, Tolbert BS |
(2015) "The
First Crystal Structure of the UP1 Domain of hnRNP A1
Bound to RNA Reveals a New Look for an Old RNA Binding
Protein." J.Mol.Biol.,
427, 3241-3257. doi: 10.1016/j.jmb.2015.05.009.
|
Structure of up1 bound to RNA 5'-agu-3' . SNAP output
|
|
4ypb
|
ribosome |
X-ray (3.4 Å) |
Schureck MA, Dunkle JA, Maehigashi T, Miles SJ,
Dunham CM |
(2015) "Defining
the mRNA recognition signature of a bacterial toxin
protein." Proc.Natl.Acad.Sci.USA,
112, 13862-13867. doi: 10.1073/pnas.1512959112.
|
Precleavage 70s structure of the p. vulgaris higb
deltah92 toxin bound to the aaa codon . SNAP output
|
|
4yvi
|
transferase-RNA |
X-ray (3.01 Å) |
Ito T, Masuda I, Yoshida K, Goto-Ito S, Sekine S, Suh
SW, Hou YM, Yokoyama S |
(2015) "Structural
basis for methyl-donor-dependent and sequence-specific
binding to tRNA substrates by knotted methyltransferase
TrmD." Proc.Natl.Acad.Sci.USA,
112, E4197-E4205. doi: 10.1073/pnas.1422981112.
|
Crystal structure of h. influenzae trmd in complex with
sinefungin and trna . SNAP output
|
|
4yvj
|
transferase-RNA |
X-ray (2.9 Å) |
Ito T, Masuda I, Yoshida K, Goto-Ito S, Sekine S, Suh
SW, Hou YM, Yokoyama S |
(2015) "Structural
basis for methyl-donor-dependent and sequence-specific
binding to tRNA substrates by knotted methyltransferase
TrmD." Proc.Natl.Acad.Sci.USA,
112, E4197-E4205. doi: 10.1073/pnas.1422981112.
|
Crystal structure of h. influenzae trmd in complex with
sinefungin and trna variant (g36u) . SNAP output
|
|
4yvk
|
transferase-RNA |
X-ray (3.002 Å) |
Ito T, Masuda I, Yoshida K, Goto-Ito S, Sekine S, Suh
SW, Hou YM, Yokoyama S |
(2015) "Structural
basis for methyl-donor-dependent and sequence-specific
binding to tRNA substrates by knotted methyltransferase
TrmD." Proc.Natl.Acad.Sci.USA,
112, E4197-E4205. doi: 10.1073/pnas.1422981112.
|
Crystal structure of h. influenzae trmd in complex with
sinefungin and trna variant (g36c) . SNAP output
|
|
4yy3
|
ribosome |
X-ray (3.6 Å) |
Schureck MA, Maehigashi T, Miles SJ, Marquez J,
Dunham CM |
(2016) "mRNA
bound to the 30S subunit is a HigB toxin
substrate." Rna, 22,
1261-1270. doi: 10.1261/rna.056218.116.
|
30s ribosomal subunit- higb complex . SNAP output
|
|
4yye
|
ligase-RNA |
X-ray (2.301 Å) |
Holman KM, Wu J, Ling J, Simonovic M |
(2016) "The
crystal structure of yeast mitochondrial ThrRS in
complex with the canonical threonine tRNA."
Nucleic Acids Res., 44,
1428-1439. doi: 10.1093/nar/gkv1501.
|
Crystal structure of the yeast mitochondrial
threonyl-trna synthetase (mst1) in complex with the
canonical trnathr and threonyl sulfamoyl adenylate .
SNAP output
|
|
4yzv
|
ribosome |
X-ray (3.1 Å) |
Schureck MA, Dunkle JA, Maehigashi T, Miles SJ,
Dunham CM |
(2015) "Defining
the mRNA recognition signature of a bacterial toxin
protein." Proc.Natl.Acad.Sci.USA,
112, 13862-13867. doi: 10.1073/pnas.1512959112.
|
Precleavage 70s structure of the p. vulgaris higb
deltah92 toxin bound to the aca codon . SNAP output
|
|
4z0c
|
immune system |
X-ray (2.3 Å) |
Song W, Wang J, Han Z, Zhang Y, Zhang H, Wang W,
Chang J, Xia B, Fan S, Zhang D, Wang J, Wang HW, Chai
J |
(2015) "Structural
basis for specific recognition of single-stranded RNA
by Toll-like receptor 13."
Nat.Struct.Mol.Biol., 22,
782-787. doi: 10.1038/nsmb.3080.
|
Crystal structure of tlr13-ssrna13 complex . SNAP output
|
|
4z31
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Zhang Q, Fan L, Hou F, Dong A, Wang YX, Tong Y |
(2015) "New
Insights into the RNA-Binding and E3 Ubiquitin Ligase
Activities of Roquins." Sci Rep,
5, 15660. doi: 10.1038/srep15660.
|
Crystal structure of the rc3h2 roq domain in complex
with stem-loop and double-stranded forms of RNA .
SNAP output
|
|
4z3s
|
ribosome-antibiotic |
X-ray (2.65 Å) |
Polikanov YS, Starosta AL, Juette MF, Altman RB,
Terry DS, Lu W, Burnett BJ, Dinos G, Reynolds KA,
Blanchard SC, Steitz TA, Wilson DN |
(2015) "Distinct
tRNA Accommodation Intermediates Observed on the
Ribosome with the Antibiotics Hygromycin A and
A201A." Mol.Cell, 58,
832-844. doi: 10.1016/j.molcel.2015.04.014.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with antibiotic a201a, mrna and
three trnas in the a, p and e sites at 2.65a resolution
. SNAP output
|
|
4z4c
|
hydrolase-RNA |
X-ray (2.303 Å) |
Schirle NT, Sheu-Gruttadauria J, Chandradoss SD, Joo
C, MacRae IJ |
(2015) "Water-mediated
recognition of t1-adenosine anchors Argonaute2 to
microRNA targets." Elife,
4. doi: 10.7554/eLife.07646.
|
Human argonaute2 bound to t1-c target RNA . SNAP output
|
|
4z4d
|
gene regulation-RNA |
X-ray (1.6 Å) |
Schirle NT, Sheu-Gruttadauria J, Chandradoss SD, Joo
C, MacRae IJ |
(2015) "Water-mediated
recognition of t1-adenosine anchors Argonaute2 to
microRNA targets." Elife,
4. doi: 10.7554/eLife.07646.
|
Human argonaute2 bound to t1-g target RNA . SNAP output
|
|
4z4e
|
gene regulation-RNA |
X-ray (1.8 Å) |
Schirle NT, Sheu-Gruttadauria J, Chandradoss SD, Joo
C, MacRae IJ |
(2015) "Water-mediated
recognition of t1-adenosine anchors Argonaute2 to
microRNA targets." Elife,
4. doi: 10.7554/eLife.07646.
|
Human argonaute2 bound to t1-u target RNA . SNAP output
|
|
4z4f
|
gene regulation-RNA |
X-ray (2.8 Å) |
Schirle NT, Sheu-Gruttadauria J, Chandradoss SD, Joo
C, MacRae IJ |
(2015) "Water-mediated
recognition of t1-adenosine anchors Argonaute2 to
microRNA targets." Elife,
4. doi: 10.7554/eLife.07646.
|
Human argonaute2 bound to t1-dap target RNA . SNAP output
|
|
4z4g
|
gene regulation-RNA |
X-ray (2.7 Å) |
Schirle NT, Sheu-Gruttadauria J, Chandradoss SD, Joo
C, MacRae IJ |
(2015) "Water-mediated
recognition of t1-adenosine anchors Argonaute2 to
microRNA targets." Elife,
4. doi: 10.7554/eLife.07646.
|
Human argonaute2 bound to t1-inosine target RNA .
SNAP output
|
|
4z4h
|
gene regulation-RNA |
X-ray (2.504 Å) |
Schirle NT, Sheu-Gruttadauria J, Chandradoss SD, Joo
C, MacRae IJ |
(2015) "Water-mediated
recognition of t1-adenosine anchors Argonaute2 to
microRNA targets." Elife,
4. doi: 10.7554/eLife.07646.
|
Human argonaute2 a481t mutant bound to t1-a target RNA
. SNAP output
|
|
4z4i
|
gene regulation-RNA |
X-ray (2.801 Å) |
Schirle NT, Sheu-Gruttadauria J, Chandradoss SD, Joo
C, MacRae IJ |
(2015) "Water-mediated
recognition of t1-adenosine anchors Argonaute2 to
microRNA targets." Elife,
4. doi: 10.7554/eLife.07646.
|
Human argonaute2 a481t mutant bound to t1-g target RNA
. SNAP output
|
|
4z7k
|
hydrolase-RNA-DNA |
X-ray (3.0 Å) |
Shao Y, Richter H, Sun S, Sharma K, Urlaub H, Randau
L, Li H |
(2016) "A
Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding
Cas6." Structure, 24,
547-554. doi: 10.1016/j.str.2016.02.009.
|
Crystal structure of crispr RNA processing
endoribonuclease cas6b . SNAP output
|
|
4z7l
|
hydrolase-RNA |
X-ray (3.503 Å) |
Shao Y, Richter H, Sun S, Sharma K, Urlaub H, Randau
L, Li H |
(2016) "A
Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding
Cas6." Structure, 24,
547-554. doi: 10.1016/j.str.2016.02.009.
|
Crystal structure of cas6b . SNAP output
|
|
4z8c
|
ribosome-antibiotic |
X-ray (2.9 Å) |
Roy RN, Lomakin IB, Gagnon MG, Steitz TA |
(2015) "The
mechanism of inhibition of protein synthesis by the
proline-rich peptide oncocin."
Nat.Struct.Mol.Biol., 22,
466-469. doi: 10.1038/nsmb.3031.
|
Crystal structure of the thermus thermophilus 70s
ribosome bound to translation inhibitor oncocin .
SNAP output
|
|
4z92
|
virus |
X-ray (3.1 Å) |
Kalynych S, Palkova L, Plevka P |
(2015) "The
Structure of Human Parechovirus 1 Reveals an
Association of the RNA Genome with the Capsid."
J.Virol., 90, 1377-1386. doi:
10.1128/JVI.02346-15.
|
Crystal structure of parechovirus-1 virion . SNAP output
|
|
4zdo
|
transferase-RNA |
X-ray (2.65 Å) |
Puppala AK, French RL, Matthies D, Baxa U,
Subramaniam S, Simonovic M |
(2016) "Structural
basis for early-onset neurological disorders caused by
mutations in human selenocysteine synthase."
Sci Rep, 6, 32563. doi:
10.1038/srep32563.
|
The crystal structure of t325s mutant of human sepsecs
in complex with selenocysteine trna (trnasec) .
SNAP output
|
|
4zdp
|
transferase-RNA |
X-ray (2.703 Å) |
Puppala AK, French RL, Matthies D, Baxa U,
Subramaniam S, Simonovic M |
(2016) "Structural
basis for early-onset neurological disorders caused by
mutations in human selenocysteine synthase."
Sci Rep, 6, 32563. doi:
10.1038/srep32563.
|
The crystal structure of y334c mutant of human sepsecs
in complex with selenocysteine trna (trnasec) .
SNAP output
|
|
4zer
|
ribosome |
X-ray (3.1 Å) |
Seefeldt AC, Nguyen F, Antunes S, Perebaskine N, Graf
M, Arenz S, Inampudi KK, Douat C, Guichard G, Wilson DN,
Innis CA |
(2015) "The
proline-rich antimicrobial peptide Onc112 inhibits
translation by blocking and destabilizing the
initiation complex." Nat.Struct.Mol.Biol.,
22, 470-475. doi: 10.1038/nsmb.3034.
|
Crystal structure of the onc112 antimicrobial peptide
bound to the thermus thermophilus 70s ribosome .
SNAP output
|
|
4zld
|
RNA binding protein-RNA |
X-ray (1.6 Å) |
Sakurai S, Ohto U, Shimizu T |
(2015) "Structure
of human Roquin-2 and its complex with
constitutive-decay element RNA." Acta
Crystallogr.,Sect.F, 71,
1048-1054. doi: 10.1107/S2053230X15011887.
|
Crystal structure of human roquin-2 roq domain in
complex with roquin cde RNA . SNAP output
|
|
4zlr
|
translation |
X-ray (2.3 Å) |
Loedige I, Jakob L, Treiber T, Ray D, Stotz M,
Treiber N, Hennig J, Cook KB, Morris Q, Hughes TR,
Engelmann JC, Krahn MP, Meister G |
(2015) "The
Crystal Structure of the NHL Domain in Complex with RNA
Reveals the Molecular Basis of Drosophila
Brain-Tumor-Mediated Gene Regulation." Cell
Rep, 13, 1206-1220. doi: 10.1016/j.celrep.2015.09.068.
|
Structure of the brat-nhl domain bound to consensus RNA
motif . SNAP output
|
|
4zsn
|
ribosome |
X-ray (3.6 Å) |
Schureck MA, Repack A, Miles SJ, Marquez J, Dunham
CM |
(2016) "Mechanism
of endonuclease cleavage by the HigB toxin."
Nucleic Acids Res., 44,
7944-7953. doi: 10.1093/nar/gkw598.
|
70s-wild-type higb toxin complex bound to a aaa lysine
codon . SNAP output
|
|
4zt0
|
hydrolase-RNA |
X-ray (2.9 Å) |
Jiang F, Zhou K, Ma L, Gressel S, Doudna JA |
(2015) "A
Cas9-guide RNA complex preorganized for target DNA
recognition." Science,
348, 1477-1481. doi: 10.1126/science.aab1452.
|
Crystal structure of catalytically-active streptococcus
pyogenes cas9 in complex with single-guide RNA at 2.9
angstrom resolution . SNAP output
|
|
4zt9
|
hydrolase-RNA |
X-ray (3.1 Å) |
Jiang F, Zhou K, Ma L, Gressel S, Doudna JA |
(2015) "A
Cas9-guide RNA complex preorganized for target DNA
recognition." Science,
348, 1477-1481. doi: 10.1126/science.aab1452.
|
Nuclease-inactive streptococcus pyogenes cas9
(d10a-h840a, dcas9) in complex with single-guide RNA at
3.1 angstrom resolution . SNAP output
|
|
5a0t
|
hydrolase-RNA |
X-ray (2.283 Å) |
Pei XY, Bralley P, Jones GH, Luisi BF |
(2015) "Linkage
of Catalysis and 5' End Recognition in Ribonuclease
Rnase J." Nucleic Acids Res.,
43, 8066. doi: 10.1093/NAR/GKV732.
|
Catalysis and 5' end sensing by ribonuclease rnase j of
the metallo- beta-lactamase family . SNAP output
|
|
5a2q
|
ribosome |
cryo-EM (3.9 Å) |
Quade N, Boehringer D, Leibundgut M, Van Den Heuvel
J, Ban N |
(2015) "Cryo-Em
Structure of Hepatitis C Virus Ires Bound to the Human
Ribosome at 3.9 Angstrom Resolution."
Nat.Commun., 6, 7646. doi:
10.1038/NCOMMS8646.
|
Structure of the hcv ires bound to the human ribosome .
SNAP output
|
|
5a2t
|
viral protein |
cryo-EM (5.6 Å) |
Dimaio F, Chen C, Yu X, Frenz B, Hsu Y, Lin N,
Egelman EH |
(2015) "The
Molecular Basis for Flexibility in the Flexible
Filamentous Plant Viruses."
Nat.Struct.Mol.Biol., 22,
642. doi: 10.1038/NSMB.3054.
|
The molecular basis for flexibility in the flexible
filamentous plant viruses . SNAP output
|
|
5a79
|
virus |
cryo-EM (4.1 Å) |
Clare DK, Pechnikova EV, Skurat EV, Makarov VV,
Sokolova OS, Solovyev AG, Orlova EV |
(2015) "Novel
Inter-Subunit Contacts in Barley Stripe Mosaic Virus
Revealed by Cryo-Electron Microscopy."
Structure, 23, 1815. doi:
10.1016/J.STR.2015.06.028.
|
Novel inter-subunit contacts in barley stripe mosaic
virus revealed by cryo-EM . SNAP output
|
|
5a7a
|
virus |
cryo-EM (4.1 Å) |
Clare DK, Pechnikova EV, Skurat EV, Makarov VV,
Sokolova OS, Solovyev AG, Orlova EV |
(2015) "Novel
Inter-Subunit Contacts in Barley Stripe Mosaic Virus
Revealed by Cryo-Electron Microscopy."
Structure, 23, 1815. doi:
10.1016/J.STR.2015.06.028.
|
Novel inter-subunit contacts in barley stripe mosaic
virus revealed by cryo-EM . SNAP output
|
|
5a8l
|
translation |
cryo-EM (3.8 Å) |
Matheisl S, Berninghausen O, Becker T, Beckmann
R |
(2015) "Structure
of a Human Translation Termination Complex."
Nucleic Acids Res., 43, 8615.
doi: 10.1093/NAR/GKV909.
|
Human erf1 and the hcmv nascent peptide in the
translation termination complex . SNAP output
|
|
5a9z
|
ribosome |
cryo-EM (4.7 Å) |
Kumar V, Chen Y, Ero R, Ahmed T, Tan J, Li Z, Wong
ASW, Bhushan S, Gao Y |
(2015) "Structure
of Bipa in GTP Form Bound to the Ratcheted
Ribosome." Proc.Natl.Acad.Sci.USA,
112, 10944-10949. doi: 10.1073/PNAS.1513216112.
|
Complex of thermous thermophilus ribosome bound to
bipa-gdpcp . SNAP
output
|
|
5aa0
|
ribosome |
cryo-EM (5.0 Å) |
Kumar V, Chen Y, Ero R, Ahmed T, Tan J, Li Z, Wong
ASW, Bhushan S, Gao Y |
(2015) "Structure
of Bipa in GTP Form Bound to the Ratcheted
Ribosome." Proc.Natl.Acad.Sci.USA,
112, 10944-10949. doi: 10.1073/PNAS.1513216112.
|
Complex of thermous thermophilus ribosome (a-and p-site
trna) bound to bipa-gdpcp . SNAP output
|
|
5ady
|
ribosome |
cryo-EM (4.5 Å) |
Zhang Y, Mandava CS, Cao W, Li X, Zhang D, Li N,
Zhang Y, Zhang X, Qin Y, Mi K, Lei J, Sanyal S, Gao
N |
(2015) "Hflx is
a Ribosome Splitting Factor Rescuing Stalled Ribosomes
Under Stress Conditions."
Nat.Struct.Mol.Biol., 22,
906. doi: 10.1038/NSMB.3103.
|
cryo-EM structures of the 50s ribosome subunit bound
with hflx . SNAP
output
|
|
5afi
|
ribosome |
cryo-EM (2.9 Å) |
Fischer N, Neumann P, Konevega AL, Bock LV, Ficner R,
Rodnina MV, Stark H |
(2015) "Structure
of the E. coli ribosome-EF-Tu complex at <3 angstrom
resolution by Cs-corrected cryo-EM."
Nature, 520, 567-570. doi:
10.1038/nature14275.
|
2.9a structure of e. coli ribosome-ef-tu complex by
cs-corrected cryo-EM . SNAP output
|
|
5ah5
|
ligase-RNA |
X-ray (2.1 Å) |
Chopra S, Palencia A, Virus C, Schulwitz S, Temple
BR, Cusack S, Reader J |
(2016) "Structural
Characterization of Antibiotic Self-Immunity tRNA
Synthetase in Plant Tumour Biocontrol Agent."
Nat.Commun., 7, 12928. doi:
10.1038/NCOMMS12928.
|
Crystal structure of the ternary complex of
agrobacterium radiobacter k84 agnb2 leurs-trna-leuams .
SNAP output
|
|
5aj0
|
ribosome |
cryo-EM (3.5 Å) |
Behrmann E, Loerke J, Budkevich TV, Yamamoto K,
Schmidt A, Penczek PA, Vos MR, Burger J, Mielke T,
Scheerer P, Spahn CMT |
(2015) "Structural
Snapshots of Actively Translating Human Ribosomes."
Cell(Cambridge,Mass.), 161,
845-857. doi: 10.1016/j.cell.2015.03.052.
|
Cryo electron microscopy of actively translating human
polysomes (post state). . SNAP output
|
|
5aj3
|
ribosome |
cryo-EM (3.6 Å) |
Greber BJ, Bieri P, Leibundgut M, Leitner A,
Aebersold R, Boehringer D, Ban N |
(2015) "Ribosome.
The complete structure of the 55S mammalian
mitochondrial ribosome." Science,
348, 303-308. doi: 10.1126/science.aaa3872.
|
Structure of the small subunit of the mammalian
mitoribosome . SNAP
output
|
|
5aj4
|
ribosome |
cryo-EM (3.8 Å) |
Greber BJ, Bieri P, Leibundgut M, Leitner A,
Aebersold R, Boehringer D, Ban N |
(2015) "The
complete structure of the 55S mammalian mitochondrial
ribosome." Science, 348,
303-308. doi: 10.1126/science.aaa3872.
|
Structure of the 55s mammalian mitoribosome. . SNAP output
|
|
5aka
|
ribosome |
cryo-EM (5.7 Å) |
von Loeffelholz O, Jiang Q, Ariosa A, Karuppasamy M,
Huard K, Berger I, Shan S, Schaffitzel C |
(2015) "Ribosome-Srp-Ftsy
Cotranslational Targeting Complex in the Closed
State." Proc.Natl.Acad.Sci.USA,
112, 3943-3948. doi: 10.1073/PNAS.1424453112.
|
Em structure of ribosome-srp-ftsy complex in closed
state . SNAP output
|
|
5amq
|
hydrolase |
X-ray (3.0 Å) |
Gerlach P, Malet H, Cusack S, Reguera J |
(2015) "Structural
Insights Into Bunyavirus Replication and its Regulation
by the Vrna Promoter." Cell,
161, 1267-1279. doi: 10.1016/J.CELL.2015.05.006.
|
Structure of the la crosse bunyavirus polymerase in
complex with the 3' and 5' viral RNA . SNAP output
|
|
5amr
|
hydrolase |
X-ray (2.57 Å) |
Gerlach P, Malet H, Cusack S, Reguera J |
(2015) "Structural
Insights Into Bunyavirus Replication and its Regulation
by the Vrna Promoter."
Cell(Cambridge,Mass.), 161,
1267. doi: 10.1016/J.CELL.2015.05.006.
|
Structure of the la crosse bunyavirus polymerase in
complex with the 3' viral RNA . SNAP output
|
|
5an9
|
translation |
cryo-EM (3.3 Å) |
Weis F, Giudice E, Churcher M, Jin L, Hilcenko C,
Wong CC, Traynor D, Kay RR, Warren AJ |
(2015) "Mechanism
of Eif6 Release from the Nascent 60S Ribosomal
Subunit." Nat.Struct.Mol.Biol.,
22, 914. doi: 10.1038/NSMB.3112.
|
Mechanism of eif6 release from the nascent 60s
ribosomal subunit . SNAP
output
|
|
5anb
|
translation |
cryo-EM (4.1 Å) |
Weis F, Giudice E, Churcher M, Jin L, Hilcenko C,
Wong CC, Traynor D, Kay RR, Warren AJ |
(2015) "Mechanism
of Eif6 Release from the Nascent 60S Ribosomal
Subunit." Nat.Struct.Mol.Biol.,
22, 914. doi: 10.1038/NSMB.3112.
|
Mechanism of eif6 release from the nascent 60s
ribosomal subunit . SNAP
output
|
|
5anc
|
translation |
cryo-EM (4.2 Å) |
Weis F, Giudice E, Churcher M, Jin L, Hilcenko C,
Wong CC, Traynor D, Kay RR, Warren AJ |
(2015) "Mechanism
of Eif6 Release from the Nascent 60S Ribosomal
Subunit." Nat.Struct.Mol.Biol.,
22, 914. doi: 10.1038/NSMB.3112.
|
Mechanism of eif6 release from the nascent 60s
ribosomal subunit . SNAP
output
|
|
5aor
|
hydrolase-RNA |
X-ray (2.08 Å) |
Prabu JR, Muller M, Thomae AW, Schussler S, Bonneau
F, Becker PB, Conti E |
(2015) "Structure
of the RNA Helicase Mle Reveals the Molecular
Mechanisms for Uridine Specificity and RNA-ATP
Coupling." Mol.Cell, 60,
487. doi: 10.1016/J.MOLCEL.2015.10.011.
|
Structure of mle RNA adp alf4 complex . SNAP output
|
|
5apn
|
ribosome |
cryo-EM (3.91 Å) |
Greber BJ, Gerhardy S, Leitner A, Leibundgut M, Salem
M, Boehringer D, Leulliot N, Aebersold R, Panse VG, Ban
N |
(2015) "Insertion
of the Biogenesis Factor Rei1 Probes the Ribosomal
Tunnel during 60S Maturation." Cell,
164, 91. doi: 10.1016/J.CELL.2015.11.027.
|
Structure of the yeast 60s ribosomal subunit in complex
with arx1, alb1 and n-terminally tagged rei1 . SNAP output
|
|
5apo
|
ribosome |
cryo-EM (3.41 Å) |
Greber BJ, Gerhardy S, Leitner A, Leibundgut M, Salem
M, Boehringer D, Leulliot N, Aebersold R, Panse VG, Ban
N |
(2016) "Insertion
of the Biogenesis Factor Rei1 Probes the Ribosomal
Tunnel during 60S Maturation."
Cell(Cambridge,Mass.), 164,
91-102. doi: 10.1016/j.cell.2015.11.027.
|
Structure of the yeast 60s ribosomal subunit in complex
with arx1, alb1 and c-terminally tagged rei1 . SNAP output
|
|
5axm
|
transferase-RNA |
X-ray (2.21 Å) |
Kimura S, Suzuki T, Chen M, Kato K, Yu J, Nakamura A,
Tanaka I, Yao M |
(2016) "Template-dependent
nucleotide addition in the reverse (3'-5') direction by
Thg1-like protein." Sci Adv,
2, e1501397. doi: 10.1126/sciadv.1501397.
|
Crystal structure of thg1 like protein (tlp) with
trna(phe) . SNAP
output
|
|
5axn
|
transferase-RNA |
X-ray (2.703 Å) |
Kimura S, Suzuki T, Chen M, Kato K, Yu J, Nakamura A,
Tanaka I, Yao M |
(2016) "Template-dependent
nucleotide addition in the reverse (3'-5') direction by
Thg1-like protein." Sci Adv,
2, e1501397. doi: 10.1126/sciadv.1501397.
|
Crystal structure of thg1 like protein (tlp) with
trna(phe) and gdpnp . SNAP output
|
|
5b63
|
ligase |
X-ray (3.0 Å) |
Zhou M, Ye S, Stephen P, Zhang R, Wang ED, Giege R,
Lin SX |
"Crystal structures of E.coli arginyl-tRNA synthetase
(ArgRS) in complex with substrate tRNA(Arg)." |
Crystal structures of e.coli arginyl-trna synthetase
(argrs) in complex with substrate trna(arg) . SNAP output
|
|
5bkl
|
virus-RNA |
X-ray (2.94 Å) |
McPherson A |
(2021) "Structures
of additional crystal forms of Satellite tobacco mosaic
virus grown from a variety of salts." Acta
Crystallogr.,Sect.F, 77, 473-483.
doi: 10.1107/S2053230X21011547.
|
Crystallographic structure of the cubic crystal form of
stmv (77.9 degree rotation) grown from nacl . SNAP output
|
|
5bkn
|
virus |
X-ray (3.0 Å) |
McPherson A |
(2021) "Structures
of additional crystal forms of Satellite tobacco mosaic
virus grown from a variety of salts." Acta
Crystallogr.,Sect.F, 77, 473-483.
doi: 10.1107/S2053230X21011547.
|
Crystallographic structure of a cubic crystal form of
stmv (84.5 degree rotation) grown from chloride .
SNAP output
|
|
5br8
|
ribosome |
X-ray (3.4 Å) |
Sierra RG, Gati C, Laksmono H, Dao EH, Gul S, Fuller
F, Kern J, Chatterjee R, Ibrahim M, Brewster A, Young ID,
Michels-Clark T, Aquila A, Mengning L, Hunter MS, Koglin
JE, Boutet S, Junco EA, Hayes B, Bogan MJ, Hampton CY,
Puglisi EV, Sauter NK, Stan CA, Zouni A, Yano J,
Yachandra VK, Soltis SM, Puglisi JD, DeMirci H |
"Ambient-temperature crystal structure of 30S
ribosomal subunit from Thermus thermophilus in complex
with paromomycin." |
Ambient-temperature crystal structure of 30s ribosomal
subunit from thermus thermophilus in complex with
paromomycin . SNAP
output
|
|
5bte
|
hydrolase-RNA |
X-ray (2.4 Å) |
Wang VY, Jiao X, Kiledjian M, Tong L |
(2015) "Structural
and biochemical studies of the distinct activity
profiles of Rai1 enzymes." Nucleic Acids
Res., 43, 6596-6606. doi:
10.1093/nar/gkv620.
|
Crystal structure of ashbya gossypii rai1 in complex
with pu(s)6-mn2+ . SNAP
output
|
|
5bud
|
hydrolase-RNA |
X-ray (1.99 Å) |
Wang VY, Jiao X, Kiledjian M, Tong L |
(2015) "Structural
and biochemical studies of the distinct activity
profiles of Rai1 enzymes." Nucleic Acids
Res., 43, 6596-6606. doi:
10.1093/nar/gkv620.
|
Crystal structure of candida albicans rai1 in complex
with pu5-mn2+ . SNAP
output
|
|
5bym
|
RNA binding protein-RNA |
X-ray (2.708 Å) |
Wilinski D, Qiu C, Lapointe CP, Nevil M, Campbell ZT,
Tanaka Hall TM, Wickens M |
(2015) "RNA
regulatory networks diversified through curvature of
the PUF protein scaffold." Nat Commun,
6, 8213. doi: 10.1038/ncomms9213.
|
Crystal structure of the RNA-binding domain of yeast
puf5p bound to smx2 RNA . SNAP output
|
|
5bz1
|
RNA binding protein-RNA |
X-ray (2.15 Å) |
Wilinski D, Qiu C, Lapointe CP, Nevil M, Campbell ZT,
Tanaka Hall TM, Wickens M |
(2015) "RNA
regulatory networks diversified through curvature of
the PUF protein scaffold." Nat Commun,
6, 8213. doi: 10.1038/ncomms9213.
|
Crystal structure of the RNA-binding domain of yeast
puf5p bound to mfa2 RNA . SNAP output
|
|
5bz5
|
RNA binding protein-RNA |
X-ray (2.8 Å) |
Wilinski D, Qiu C, Lapointe CP, Nevil M, Campbell ZT,
Tanaka Hall TM, Wickens M |
(2015) "RNA
regulatory networks diversified through curvature of
the PUF protein scaffold." Nat Commun,
6, 8213. doi: 10.1038/ncomms9213.
|
Crystal structure of the RNA-binding domain of yeast
puf5p bound to amn1 RNA . SNAP output
|
|
5bzu
|
RNA binding protein-RNA |
X-ray (2.501 Å) |
Wilinski D, Qiu C, Lapointe CP, Nevil M, Campbell ZT,
Tanaka Hall TM, Wickens M |
(2015) "RNA
regulatory networks diversified through curvature of
the PUF protein scaffold." Nat Commun,
6, 8213. doi: 10.1038/ncomms9213.
|
Crystal structure of the RNA-binding domain of yeast
puf5p bound to aat2 RNA . SNAP output
|
|
5bzv
|
RNA binding protein-RNA |
X-ray (2.354 Å) |
Wilinski D, Qiu C, Lapointe CP, Nevil M, Campbell ZT,
Tanaka Hall TM, Wickens M |
(2015) "RNA
regulatory networks diversified through curvature of
the PUF protein scaffold." Nat Commun,
6, 8213. doi: 10.1038/ncomms9213.
|
Crystal structure of the RNA-binding domain of yeast
puf5p bound to smx2 RNA . SNAP output
|
|
5c0w
|
hydrolase-RNA |
X-ray (4.6 Å) |
Makino DL, Schuch B, Stegmann E, Baumgartner M,
Basquin C, Conti E |
(2015) "RNA
degradation paths in a 12-subunit nuclear exosome
complex." Nature, 524,
54-58. doi: 10.1038/nature14865.
|
Structure of a 12-subunit nuclear exosome complex bound
to single-stranded RNA substrates . SNAP output
|
|
5c0x
|
hydrolase-RNA |
X-ray (3.812 Å) |
Makino DL, Schuch B, Stegmann E, Baumgartner M,
Basquin C, Conti E |
(2015) "RNA
degradation paths in a 12-subunit nuclear exosome
complex." Nature, 524,
54-58. doi: 10.1038/nature14865.
|
Structure of a 12-subunit nuclear exosome complex bound
to structured RNA . SNAP
output
|
|
5c9h
|
RNA binding protein-RNA |
X-ray (3.0 Å) |
Jansson LI, Akiyama BM, Ooms A, Lu C, Rubin SM, Stone
MD |
(2015) "Structural
basis of template-boundary definition in Tetrahymena
telomerase." Nat.Struct.Mol.Biol.,
22, 883-888. doi: 10.1038/nsmb.3101.
|
Structural basis of template boundary definition in
tetrahymena telomerase . SNAP output
|
|
5ccb
|
transferase-RNA |
X-ray (2.0 Å) |
Finer-Moore J, Czudnochowski N, O'Connell JD, Wang
AL, Stroud RM |
(2015) "Crystal
Structure of the Human tRNA m(1)A58
Methyltransferase-tRNA3(Lys) Complex: Refolding of
Substrate tRNA Allows Access to the Methylation
Target." J.Mol.Biol.,
427, 3862-3876. doi: 10.1016/j.jmb.2015.10.005.
|
Crystal structure of human m1a58 methyltransferase in a
complex with trna3lys and sah . SNAP output
|
|
5ccx
|
transferase-RNA |
X-ray (2.1 Å) |
Finer-Moore J, Czudnochowski N, O'Connell JD, Wang
AL, Stroud RM |
(2015) "Crystal
Structure of the Human tRNA m(1)A58
Methyltransferase-tRNA3(Lys) Complex: Refolding of
Substrate tRNA Allows Access to the Methylation
Target." J.Mol.Biol.,
427, 3862-3876. doi: 10.1016/j.jmb.2015.10.005.
|
Structure of the product complex of trna m1a58
methyltransferase with trna3lys as substrate . SNAP output
|
|
5cd1
|
transferase-RNA |
X-ray (3.6 Å) |
Finer-Moore J, Czudnochowski N, O'Connell JD, Wang
AL, Stroud RM |
(2015) "Crystal
Structure of the Human tRNA m(1)A58
Methyltransferase-tRNA3(Lys) Complex: Refolding of
Substrate tRNA Allows Access to the Methylation
Target." J.Mol.Biol.,
427, 3862-3876. doi: 10.1016/j.jmb.2015.10.005.
|
Structure of an asymmetric tetramer of human trna m1a58
methyltransferase in a complex with sah and trna3lys .
SNAP output
|
|
5cd4
|
hydrolase-RNA |
X-ray (3.2 Å) |
van Erp PB, Jackson RN, Carter J, Golden SM, Bailey
S, Wiedenheft B |
(2015) "Mechanism
of CRISPR-RNA guided recognition of DNA targets in
Escherichia coli." Nucleic Acids Res.,
43, 8381-8391. doi: 10.1093/nar/gkv793.
|
The type ie crispr cascade complex from e. coli, with
two assemblies in the asymmetric unit arranged
back-to-back . SNAP
output
|
|
5czp
|
ribosome |
X-ray (3.3 Å) |
Pierson WE, Hoffer ED, Keedy HE, Simms CL, Dunham CM,
Zaher HS |
(2016) "Uniformity
of Peptide Release Is Maintained by Methylation of
Release Factors." Cell Rep,
17, 11-18. doi: 10.1016/j.celrep.2016.08.085.
|
70s termination complex containing e. coli rf2 .
SNAP output
|
|
5d0a
|
oxidoreductase-RNA |
X-ray (2.1 Å) |
Dowling DP, Miles ZD, Kohrer C, Maiocco SJ, Elliott
SJ, Bandarian V, Drennan CL |
(2016) "Molecular
basis of cobalamin-dependent RNA modification."
Nucleic Acids Res., 44,
9965-9976. doi: 10.1093/nar/gkw806.
|
Crystal structure of epoxyqueuosine reductase with
cleaved RNA stem loop . SNAP output
|
|
5d0b
|
oxidoreductase-RNA |
X-ray (2.645 Å) |
Dowling DP, Miles ZD, Kohrer C, Maiocco SJ, Elliott
SJ, Bandarian V, Drennan CL |
(2016) "Molecular
basis of cobalamin-dependent RNA modification."
Nucleic Acids Res., 44,
9965-9976. doi: 10.1093/nar/gkw806.
|
Crystal structure of epoxyqueuosine reductase with a
trna-tyr epoxyqueuosine-modified trna stem loop .
SNAP output
|
|
5d6g
|
translation |
X-ray (3.3 Å) |
Gabdulkhakov AG, Mitroshin IV, Garber MB |
"CRYSTAL STRUCTURE OF FRAGMENT OF RIBOSOMAL PROTEIN
P0 IN COMPLEX WITH 74NT 23S RNA FROM METHANOCOCCUS
JANNASCHII." |
Crystal structure of fragment of ribosomal protein p0
in complex with 74nt 23s RNA from methanococcus
jannaschii . SNAP
output
|
|
5d8b
|
translation |
X-ray (3.63 Å) |
Svidritskiy E, Korostelev AA |
(2015) "Ribosome
Structure Reveals Preservation of Active Sites in the
Presence of a P-Site Wobble Mismatch."
Structure, 23, 2155-2161.
doi: 10.1016/j.str.2015.08.011.
|
Crystal structure of t. thermophilus ribosome
containing a p-site wobble mismatch . SNAP output
|
|
5d8h
|
ribosomal protein |
X-ray (2.8 Å) |
Gabdulkhakov AG, Mitroshin IV, Garber MB |
"CRYSTAL STRUCTURE OF THE BASE OF THE RIBOSOMAL P
STALK FROM METHANOCOCCUS JANNASCHII WITH ANTIBIOTIC
THIOSTREPTON." |
Crystal structure of the base of the ribosomal p stalk
from methanococcus jannaschii with antibiotic
thiostrepton . SNAP
output
|
|
5dar
|
ribosomal protein |
X-ray (2.9 Å) |
Gabdulkhakov AG, Mitroshin IV, Garber MB |
"CRYSTAL STRUCTURE OF THE BASE OF THE RIBOSOMAL P
STALK FROM METHANOCOCCUS JANNASCHII." |
Crystal structure of the base of the ribosomal p stalk
from methanococcus jannaschii . SNAP output
|
|
5dat
|
ribosome |
X-ray (3.15 Å) |
Melnikov S, Mailliot J, Shin B-S, Rigger L, Yusupova
G, Micura R, Dever TE, Yusupov M |
"Coping with proline stalling: structural basis of
hypusine-induced protein synthesis by the eukaryotic
ribosome." |
Complex of yeast 80s ribosome with hypusine-containing
eif5a . SNAP output
|
|
5dc3
|
ribosome |
X-ray (3.25 Å) |
Melnikov S, Mailliot J, Shin BS, Rigger L, Yusupova
G, Micura R, Dever TE, Yusupov M |
(2016) "Crystal
Structure of Hypusine-Containing Translation Factor
eIF5A Bound to a Rotated Eukaryotic Ribosome."
J.Mol.Biol., 428, 3570-3576.
doi: 10.1016/j.jmb.2016.05.011.
|
Complex of yeast 80s ribosome with non-modified eif5a .
SNAP output
|
|
5dcv
|
RNA binding protein-RNA |
X-ray (3.401 Å) |
Oshima K, Kakiuchi Y, Tanaka Y, Ueda T, Nakashima T,
Kimura M, Yao M |
(2016) "Structural
basis for recognition of a kink-turn motif by an
archaeal homologue of human RNase P protein Rpp38."
Biochem.Biophys.Res.Commun.,
474, 541-546. doi: 10.1016/j.bbrc.2016.04.118.
|
Crystal structure of phorpp38-sl12m complex . SNAP output
|
|
5ddo
|
RNA binding protein-RNA |
X-ray (3.1 Å) |
Ren A, Xue Y, Peselis A, Serganov A, Al-Hashimi HM,
Patel DJ |
(2015) "Structural
and Dynamic Basis for Low-Affinity, High-Selectivity
Binding of L-Glutamine by the Glutamine
Riboswitch." Cell Rep,
13, 1800-1813. doi: 10.1016/j.celrep.2015.10.062.
|
Structural and dynamic basis for low affinity-high
selectivity binding of l-glutamine by the
gln-riboswitch . SNAP
output
|
|
5ddp
|
RNA binding protein-RNA |
X-ray (2.302 Å) |
Ren A, Xue Y, Peselis A, Serganov A, Al-Hashimi HM,
Patel DJ |
(2015) "Structural
and Dynamic Basis for Low-Affinity, High-Selectivity
Binding of L-Glutamine by the Glutamine
Riboswitch." Cell Rep,
13, 1800-1813. doi: 10.1016/j.celrep.2015.10.062.
|
L-glutamine riboswitch bound with l-glutamine .
SNAP output
|
|
5ddq
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Ren A, Xue Y, Peselis A, Serganov A, Al-Hashimi HM,
Patel DJ |
(2015) "Structural
and Dynamic Basis for Low-Affinity, High-Selectivity
Binding of L-Glutamine by the Glutamine
Riboswitch." Cell Rep,
13, 1800-1813. doi: 10.1016/j.celrep.2015.10.062.
|
L-glutamine riboswitch bound with l-glutamine soaked
with mn2+ . SNAP
output
|
|
5ddr
|
RNA binding protein-RNA |
X-ray (2.605 Å) |
Ren A, Xue Y, Peselis A, Serganov A, Al-Hashimi HM,
Patel DJ |
(2015) "Structural
and Dynamic Basis for Low-Affinity, High-Selectivity
Binding of L-Glutamine by the Glutamine
Riboswitch." Cell Rep,
13, 1800-1813. doi: 10.1016/j.celrep.2015.10.062.
|
L-glutamine riboswitch bound with l-glutamine soaked
with cs+ . SNAP
output
|
|
5de5
|
RNA binding protein-RNA |
X-ray (3.0 Å) |
Vasilyev N, Polonskaia A, Darnell JC, Darnell RB,
Patel DJ, Serganov A |
(2015) "Crystal
structure reveals specific recognition of a
G-quadruplex RNA by a beta-turn in the RGG motif of
FMRP." Proc.Natl.Acad.Sci.USA,
112, E5391-E5400. doi: 10.1073/pnas.1515737112.
|
Crystal structure of the complex between human fmrp rgg
motif and g-quadruplex RNA. . SNAP output
|
|
5de8
|
RNA binding protein-RNA |
X-ray (3.1 Å) |
Vasilyev N, Polonskaia A, Darnell JC, Darnell RB,
Patel DJ, Serganov A |
(2015) "Crystal
structure reveals specific recognition of a
G-quadruplex RNA by a beta-turn in the RGG motif of
FMRP." Proc.Natl.Acad.Sci.USA,
112, E5391-E5400. doi: 10.1073/pnas.1515737112.
|
Crystal structure of the complex between human fmrp rgg
motif and g-quadruplex RNA, iridium hexammine bound
form. . SNAP output
|
|
5dea
|
RNA binding protein-RNA |
X-ray (2.8 Å) |
Vasilyev N, Polonskaia A, Darnell JC, Darnell RB,
Patel DJ, Serganov A |
(2015) "Crystal
structure reveals specific recognition of a
G-quadruplex RNA by a beta-turn in the RGG motif of
FMRP." Proc.Natl.Acad.Sci.USA,
112, E5391-E5400. doi: 10.1073/pnas.1515737112.
|
Crystal structure of the complex between human fmrp rgg
motif and g-quadruplex RNA, cesium bound form. .
SNAP output
|
|
5det
|
RNA binding protein-RNA |
X-ray (1.95 Å) |
Teplova M, Farazi TA, Tuschl T, Patel DJ |
(2016) "Structural
basis underlying CAC RNA recognition by the RRM domain
of dimeric RNA-binding protein RBPMS." Q. Rev.
Biophys., 49, e1. doi: 10.1017/S0033583515000207.
|
X-ray structure of human rbpms in complex with the RNA
. SNAP output
|
|
5dfe
|
ribosome |
X-ray (3.1 Å) |
Pierson WE, Hoffer ED, Keedy HE, Simms CL, Dunham CM,
Zaher HS |
(2016) "Uniformity
of Peptide Release Is Maintained by Methylation of
Release Factors." Cell Rep,
17, 11-18. doi: 10.1016/j.celrep.2016.08.085.
|
70s termination complex containing e. coli rf2 .
SNAP output
|
|
5dge
|
ribosome |
X-ray (3.45 Å) |
Melnikov S, Mailliot J, Shin B-S, Rigger L, Yusupova
G, Micura R, Dever TE, Yusupov M |
"Coping with proline stalling: structural basis of
hypusine-induced protein synthesis by the eukaryotic
ribosome." |
Coping with proline stalling: structural basis of
hypusine-induced protein synthesis by the eukaryotic
ribosome . SNAP
output
|
|
5dgf
|
ribosome |
X-ray (3.3 Å) |
Melnikov S, Mailliot J, Shin B-S, Rigger L, Yusupova
G, Micura R, Dever TE, Yusupov M |
"Coping with proline stalling: structural basis of
hypusine-induced protein synthesis by the eukaryotic
ribosome." |
Complex of yeast 80s ribosome with
hypusine-containing-non-modified eif5a and-or a
peptidyl-trna analog . SNAP output
|
|
5dgv
|
ribosome |
X-ray (3.1 Å) |
Melnikov S, Mailliot J, Shin B-S, Rigger L, Yusupova
G, Micura R, Dever TE, Yusupov M |
"Coping with proline stalling: structural basis of
hypusine-induced protein synthesis by the eukaryotic
ribosome." |
Complex of yeast 80s ribosome with
hypusine-containing-non-modified eif5a and-or a
peptidyl-trna analog . SNAP output
|
|
5dm6
|
ribosome |
X-ray (2.9 Å) |
Kaminishi T, Schedlbauer A, Fabbretti A, Brandi L,
Ochoa-Lizarralde B, He CG, Milon P, Connell SR, Gualerzi
CO, Fucini P |
(2015) "Crystallographic
characterization of the ribosomal binding site and
molecular mechanism of action of Hygromycin A."
Nucleic Acids Res., 43,
10015-10025. doi: 10.1093/nar/gkv975.
|
Crystal structure of the 50s ribosomal subunit from
deinococcus radiodurans . SNAP output
|
|
5dm7
|
ribosome |
X-ray (3.0 Å) |
Kaminishi T, Schedlbauer A, Fabbretti A, Brandi L,
Ochoa-Lizarralde B, He CG, Milon P, Connell SR, Gualerzi
CO, Fucini P |
(2015) "Crystallographic
characterization of the ribosomal binding site and
molecular mechanism of action of Hygromycin A."
Nucleic Acids Res., 43,
10015-10025. doi: 10.1093/nar/gkv975.
|
Crystal structure of the 50s ribosomal subunit from
deinococcus radiodurans in complex with hygromycin a .
SNAP output
|
|
5dno
|
RNA binding protein-RNA |
X-ray (1.8 Å) |
Wang CY, Zhu YW, Bao HY, Jiang YY, Xu C, Wu JH, Shi
YY |
(2016) "A novel
RNA-binding mode of the YTH domain reveals the
mechanism for recognition of determinant of selective
removal by Mmi1." Nucleic Acids Res.,
44, 969-982. doi: 10.1093/nar/gkv1382.
|
Crystal structure of mmi1 yth domain complex with RNA .
SNAP output
|
|
5do4
|
hydrolase-RNA |
X-ray (1.859 Å) |
Abeydeera ND, Egli M, Cox N, Mercier K, Conde JN,
Pallan PS, Mizurini DM, Sierant M, Hibti FE, Hassell T,
Wang T, Liu FW, Liu HM, Martinez C, Sood AK, Lybrand TP,
Frydman C, Monteiro RQ, Gomer RH, Nawrot B, Yang X |
(2016) "Evoking
picomolar binding in RNA by a single phosphorodithioate
linkage." Nucleic Acids Res.,
44, 8052-8064. doi: 10.1093/nar/gkw725.
|
Thrombin-RNA aptamer complex . SNAP output
|
|
5dox
|
ribosome-antibiotic |
X-ray (3.1 Å) |
Polikanov YS, Starosta AL, Juette MF, Altman RB,
Terry DS, Lu W, Burnett BJ, Dinos G, Reynolds KA,
Blanchard SC, Steitz TA, Wilson DN |
(2015) "Distinct
tRNA Accommodation Intermediates Observed on the
Ribosome with the Antibiotics Hygromycin A and
A201A." Mol.Cell, 58,
832-844. doi: 10.1016/j.molcel.2015.04.014.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with hygromycin-a at 3.1a
resolution . SNAP
output
|
|
5dto
|
viral protein-RNA |
X-ray (2.603 Å) |
Zhao Y, Soh TS, Lim SP, Chung KY, Swaminathan K,
Vasudevan SG, Shi P-Y, Lescar J, Luo D |
(2015) "Molecular
basis for specific viral RNA recognition and
2'-O-ribose methylation by the dengue virus
nonstructural protein 5 (NS5)."
Proc.Natl.Acad.Sci.USA, 112,
14834-14839. doi: 10.1073/pnas.1514978112.
|
Dengue virus full length ns5 complexed with viral cap
0-RNA and sah . SNAP
output
|
|
5dv7
|
RNA binding protein |
X-ray (3.5 Å) |
Jayachandran U, Grey H, Cook AG |
(2016) "Nuclear
factor 90 uses an ADAR2-like binding mode to recognize
specific bases in dsRNA." Nucleic Acids
Res., 44, 1924-1936. doi:
10.1093/nar/gkv1508.
|
Crystal structure of nf90 tandem dsrbds with dsrna .
SNAP output
|
|
5e02
|
hydrolase, RNA binding protein-RNA |
X-ray (3.8 Å) |
Conrad KS, Hurley JM, Widom J, Ringelberg CS, Loros
JJ, Dunlap JC, Crane BR |
(2016) "Structure
of the frequency-interacting RNA helicase: a protein
interaction hub for the circadian clock." Embo
J., 35, 1707-1719. doi: 10.15252/embj.201694327.
|
Structure of RNA helicase frh a critical component of
the neurospora crassa circadian clock . SNAP output
|
|
5e08
|
immune system-RNA |
X-ray (2.38 Å) |
Shao Y, Huang H, Qin D, Li NS, Koide A, Staley JP,
Koide S, Kossiakoff AA, Piccirilli JA |
(2016) "Specific
Recognition of a Single-Stranded RNA Sequence by a
Synthetic Antibody Fragment." J.Mol.Biol.,
428, 4100-4114. doi: 10.1016/j.jmb.2016.08.029.
|
Specific recognition of a single-stranded RNA sequence
by an engineered synthetic antibody fragment . SNAP output
|
|
5e3h
|
hydrolase-RNA |
X-ray (2.7 Å) |
Jiang F, Ramanathan A, Miller MT, Tang GQ, Gale M,
Patel SS, Marcotrigiano J |
(2011) "Structural
basis of RNA recognition and activation by innate
immune receptor RIG-I." Nature,
479, 423-427. doi: 10.1038/nature10537.
|
Structural basis for RNA recognition and activation of
rig-i . SNAP output
|
|
5e6m
|
ligase-RNA |
X-ray (2.927 Å) |
Qin X, Deng X, Chen L, Xie W |
(2016) "Crystal
Structure of the Wild-Type Human GlyRS Bound with
tRNA(Gly) in a Productive Conformation."
J.Mol.Biol., 428, 3603-3614.
doi: 10.1016/j.jmb.2016.05.018.
|
Crystal structure of human wild type glyrs bound with
trnagly . SNAP
output
|
|
5e7k
|
ribosome |
X-ray (3.2 Å) |
Rozov A, Demeshkina N, Khusainov I, Westhof E,
Yusupov M, Yusupova G |
(2016) "Novel
base-pairing interactions at the tRNA wobble position
crucial for accurate reading of the genetic code."
Nat Commun, 7, 10457. doi:
10.1038/ncomms10457.
|
Structure of t. thermophilus 70s ribosome complex with
mrna and cognate trnalys in the a-site . SNAP output
|
|
5e81
|
ribosome |
X-ray (2.95 Å) |
Rozov A, Demeshkina N, Khusainov I, Westhof E,
Yusupov M, Yusupova G |
(2016) "Novel
base-pairing interactions at the tRNA wobble position
crucial for accurate reading of the genetic code."
Nat Commun, 7, 10457. doi:
10.1038/ncomms10457.
|
Structure of t. thermophilus 70s ribosome complex with
mrna and trnalys in the a-site with wobble pair .
SNAP output
|
|
5ed1
|
hydrolase-RNA |
X-ray (2.77 Å) |
Matthews MM, Thomas JM, Zheng Y, Tran K, Phelps KJ,
Scott AI, Havel J, Fisher AJ, Beal PA |
(2016) "Structures
of human ADAR2 bound to dsRNA reveal base-flipping
mechanism and basis for site selectivity."
Nat.Struct.Mol.Biol., 23,
426-433. doi: 10.1038/nsmb.3203.
|
Human adenosine deaminase acting on dsrna (adar2)
mutant e488q bound to dsrna sequence derived from s.
cerevisiae bdf2 gene . SNAP output
|
|
5ed2
|
hydrolase-RNA |
X-ray (2.95 Å) |
Matthews MM, Thomas JM, Zheng Y, Tran K, Phelps KJ,
Scott AI, Havel J, Fisher AJ, Beal PA |
(2016) "Structures
of human ADAR2 bound to dsRNA reveal base-flipping
mechanism and basis for site selectivity."
Nat.Struct.Mol.Biol., 23,
426-433. doi: 10.1038/nsmb.3203.
|
Human adenosine deaminase acting on dsrna (adar2)
mutant e488q bound to dsrna sequence derived from human
gli1 gene . SNAP
output
|
|
5eeu
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
1.31 mgy . SNAP
output
|
|
5eev
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
3.88 mgy . SNAP
output
|
|
5eew
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
6.45 mgy . SNAP
output
|
|
5eex
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
9.02 mgy . SNAP
output
|
|
5eey
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
11.6 mgy . SNAP
output
|
|
5eez
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
14.2 mgy . SNAP
output
|
|
5ef0
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
16.7 mgy . SNAP
output
|
|
5ef1
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
19.3 mgy . SNAP
output
|
|
5ef2
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
21.9 mgy . SNAP
output
|
|
5ef3
|
RNA binding protein |
X-ray (1.98 Å) |
Bury CS, McGeehan JE, Antson AA, Carmichael I,
Gerstel M, Shevtsov MB, Garman EF |
(2016) "RNA
protects a nucleoprotein complex against radiation
damage." Acta Crystallogr D Struct Biol,
72, 648-657. doi: 10.1107/S2059798316003351.
|
Radiation damage to the trap-RNA complex: dose (dwd)
25.0 mgy . SNAP
output
|
|
5eim
|
RNA binding protein-RNA |
X-ray (1.54 Å) |
Wu BX, Xu JH, Su SC, Liu H, Gan J, Ma JB |
(2017) "Structural
insights into the specific recognition of DSR by the
YTH domain containing protein Mmi1." Biochem.
Biophys. Res. Commun., 491,
310-316. doi: 10.1016/j.bbrc.2017.07.104.
|
Yth domain-containing protein mmi1 and RNA complex .
SNAP output
|
|
5el4
|
ribosome |
X-ray (3.15 Å) |
Rozov A, Demeshkina N, Khusainov I, Westhof E,
Yusupov M, Yusupova G |
(2016) "Novel
base-pairing interactions at the tRNA wobble position
crucial for accurate reading of the genetic code."
Nat Commun, 7, 10457. doi:
10.1038/ncomms10457.
|
Structure of t. thermophilus 70s ribosome complex with
mrna and trnalys in the a-site with a u-u mismatch in
the first position . SNAP output
|
|
5el5
|
ribosome |
X-ray (3.15 Å) |
Rozov A, Demeshkina N, Khusainov I, Westhof E,
Yusupov M, Yusupova G |
(2016) "Novel
base-pairing interactions at the tRNA wobble position
crucial for accurate reading of the genetic code."
Nat Commun, 7, 10457. doi:
10.1038/ncomms10457.
|
Structure of t. thermophilus 70s ribosome complex with
mrna and trnalys in the a-site with a u-u mismatch in
the second position . SNAP output
|
|
5el6
|
ribosome |
X-ray (3.1 Å) |
Rozov A, Demeshkina N, Khusainov I, Westhof E,
Yusupov M, Yusupova G |
(2016) "Novel
base-pairing interactions at the tRNA wobble position
crucial for accurate reading of the genetic code."
Nat Commun, 7, 10457. doi:
10.1038/ncomms10457.
|
Structure of t. thermophilus 70s ribosome complex with
mrna and trnalys in the a-site with a u-u mismatch in
the first position and antibiotic paromomycin .
SNAP output
|
|
5el7
|
ribosome |
X-ray (3.15 Å) |
Rozov A, Demeshkina N, Khusainov I, Westhof E,
Yusupov M, Yusupova G |
(2016) "Novel
base-pairing interactions at the tRNA wobble position
crucial for accurate reading of the genetic code."
Nat Commun, 7, 10457. doi:
10.1038/ncomms10457.
|
Structure of t. thermophilus 70s ribosome complex with
mrna and trnalys in the a-site with a u-u mismatch in
the second position and antibiotic paromomycin .
SNAP output
|
|
5elh
|
RNA binding protein-RNA |
X-ray (1.8 Å) |
Murn J, Teplova M, Zarnack K, Shi Y, Patel DJ |
(2016) "Recognition
of distinct RNA motifs by the clustered CCCH zinc
fingers of neuronal protein Unkempt."
Nat.Struct.Mol.Biol., 23,
16-23. doi: 10.1038/nsmb.3140.
|
Crystal structure of mouse unkempt zinc fingers 1-3
(znf1-3), bound to RNA . SNAP output
|
|
5elr
|
RNA binding protein |
X-ray (2.3 Å) |
Feracci M, Foot JN, Grellscheid SN, Danilenko M,
Stehle R, Gonchar O, Kang HS, Dalgliesh C, Meyer NH, Liu
Y, Lahat A, Sattler M, Eperon IC, Elliott DJ, Dominguez
C |
(2016) "Structural
basis of RNA recognition and dimerization by the STAR
proteins T-STAR and Sam68." Nat Commun,
7, 10355. doi: 10.1038/ncomms10355.
|
Structure of the kh-qua2 domain of t-star in complex
with aauaau RNA . SNAP
output
|
|
5els
|
RNA binding protein |
X-ray (2.873 Å) |
Feracci M, Foot JN, Grellscheid SN, Danilenko M,
Stehle R, Gonchar O, Kang HS, Dalgliesh C, Meyer NH, Liu
Y, Lahat A, Sattler M, Eperon IC, Elliott DJ, Dominguez
C |
(2016) "Structural
basis of RNA recognition and dimerization by the STAR
proteins T-STAR and Sam68." Nat Commun,
7, 10355. doi: 10.1038/ncomms10355.
|
Structure of the kh domain of t-star in complex with
aaauaa RNA . SNAP
output
|
|
5elt
|
RNA binding protein |
X-ray (2.13 Å) |
Feracci M, Foot JN, Grellscheid SN, Danilenko M,
Stehle R, Gonchar O, Kang HS, Dalgliesh C, Meyer NH, Liu
Y, Lahat A, Sattler M, Eperon IC, Elliott DJ, Dominguez
C |
(2016) "Structural
basis of RNA recognition and dimerization by the STAR
proteins T-STAR and Sam68." Nat Commun,
7, 10355. doi: 10.1038/ncomms10355.
|
Structure of the qua1-kh domain of t-star in complex
with uaau RNA . SNAP
output
|
|
5elx
|
hydrolase |
X-ray (1.81 Å) |
Wong EV, Cao W, Voros J, Merchant M, Modis Y, Hackney
DD, Montpetit B, De La Cruz EM |
(2016) "Pi
Release Limits the Intrinsic and RNA-Stimulated ATPase
Cycles of DEAD-Box Protein 5 (Dbp5)."
J.Mol.Biol., 428, 492-508.
doi: 10.1016/j.jmb.2015.12.018.
|
S. cerevisiae dbp5 bound to RNA and mant-adp bef3 .
SNAP output
|
|
5emo
|
RNA binding protein |
X-ray (3.03 Å) |
Feracci M, Foot JN, Grellscheid SN, Danilenko M,
Stehle R, Gonchar O, Kang HS, Dalgliesh C, Meyer NH, Liu
Y, Lahat A, Sattler M, Eperon IC, Elliott DJ, Dominguez
C |
(2016) "Structural
basis of RNA recognition and dimerization by the STAR
proteins T-STAR and Sam68." Nat Commun,
7, 10355. doi: 10.1038/ncomms10355.
|
Structure of the star domain of t-star in complex with
auuaaa RNA . SNAP
output
|
|
5en1
|
RNA binding protein-RNA |
X-ray (2.58 Å) |
Wu BX, Su SC, Patil DP, Liu HH, Gan JH, Jaffrey SR,
Ma JB |
(2018) "Molecular basis for the specific and
multivariant recognitions of RNA substrates by human
hnRNP A2/B1." Nat Commun. doi: 10.1038/s41467-017-02770-z.
|
Crystal structure of hnrnpa2b1 in complex with RNA .
SNAP output
|
|
5epi
|
transferase |
X-ray (4.1 Å) |
Thierry E, Guilligay D, Kosinski J, Bock T, Gaudon S,
Round A, Pflug A, Hengrung N, El Omari K, Baudin F, Hart
DJ, Beck M, Cusack S |
(2016) "Influenza
Polymerase Can Adopt an Alternative Configuration
Involving a Radical Repacking of PB2 Domains."
Mol.Cell, 61, 125-137. doi:
10.1016/j.molcel.2015.11.016.
|
Crystal structure of influenza b polymerase with bound
5' crna exhibits a novel domain arrangement . SNAP output
|
|
5ex7
|
translation-RNA |
X-ray (2.6 Å) |
Wang Y, Yu Z, Wang M, Liu CP, Yang N, Xu RM |
"Crystal structure of Brat NHL domain in complex with
an 8-nt hunchback mRNA." |
Crystal structure of brat nhl domain in complex with an
8-nt hunchback mrna . SNAP output
|
|
5f5f
|
RNA binding protein |
X-ray (3.0 Å) |
Janowski R, Heinz GA, Schlundt A, Wommelsdorf N,
Brenner S, Gruber AR, Blank M, Buch T, Buhmann R, Zavolan
M, Niessing D, Heissmeyer V, Sattler M |
(2016) "Roquin
recognizes a non-canonical hexaloop structure in the
3'-UTR of Ox40." Nat Commun,
7, 11032. doi: 10.1038/ncomms11032.
|
X-ray structure of roquin roq domain in complex with a
selex-derived hexa-loop RNA motif . SNAP output
|
|
5f5h
|
RNA binding protein |
X-ray (2.23 Å) |
Janowski R, Heinz GA, Schlundt A, Wommelsdorf N,
Brenner S, Gruber AR, Blank M, Buch T, Buhmann R, Zavolan
M, Niessing D, Heissmeyer V, Sattler M |
(2016) "Roquin
recognizes a non-canonical hexaloop structure in the
3'-UTR of Ox40." Nat Commun,
7, 11032. doi: 10.1038/ncomms11032.
|
X-ray structure of roquin roq domain in complex with
ox40 hexa-loop RNA motif . SNAP output
|
|
5f6c
|
hydrolase |
X-ray (3.002 Å) |
Bandyra KJ, Wandzik JM, Luisi BF |
(2018) "Substrate
Recognition and Autoinhibition in the Central
Ribonuclease RNase E." Mol. Cell,
72, 275-285.e4. doi: 10.1016/j.molcel.2018.08.039.
|
The structure of e. coli rnase e catalytically inactive
mutant with RNA bound . SNAP output
|
|
5f8g
|
transferase-RNA |
X-ray (2.78 Å) |
Shu B, Gong P |
(2016) "Structural
basis of viral RNA-dependent RNA polymerase catalysis
and translocation."
Proc.Natl.Acad.Sci.USA, 113,
E4005-E4014. doi: 10.1073/pnas.1602591113.
|
Enterovirus 71 polymerase elongation complex (c1s1
form) . SNAP output
|
|
5f8h
|
transferase-RNA |
X-ray (2.45 Å) |
Shu B, Gong P |
(2016) "Structural
basis of viral RNA-dependent RNA polymerase catalysis
and translocation."
Proc.Natl.Acad.Sci.USA, 113,
E4005-E4014. doi: 10.1073/pnas.1602591113.
|
Enterovirus 71 polymerase elongation complex (c1s1-2
form) . SNAP output
|
|
5f8i
|
transferase-RNA |
X-ray (2.503 Å) |
Shu B, Gong P |
(2016) "Structural
basis of viral RNA-dependent RNA polymerase catalysis
and translocation."
Proc.Natl.Acad.Sci.USA, 113,
E4005-E4014. doi: 10.1073/pnas.1602591113.
|
Enterovirus 71 polymerase elongation complex (c1s2-3
form) . SNAP output
|
|
5f8j
|
transferase-RNA |
X-ray (2.675 Å) |
Shu B, Gong P |
(2016) "Structural
basis of viral RNA-dependent RNA polymerase catalysis
and translocation."
Proc.Natl.Acad.Sci.USA, 113,
E4005-E4014. doi: 10.1073/pnas.1602591113.
|
Enterovirus 71 polymerase elongation complex (c1s4
form) . SNAP output
|
|
5f8k
|
ribosome |
X-ray (2.8 Å) |
Seefeldt AC, Graf M, Perebaskine N, Nguyen F, Arenz
S, Mardirossian M, Scocchi M, Wilson DN, Innis CA |
(2016) "Structure
of the mammalian antimicrobial peptide Bac7(1-16) bound
within the exit tunnel of a bacterial ribosome."
Nucleic Acids Res., 44,
2429-2438. doi: 10.1093/nar/gkv1545.
|
Crystal structure of the bac7(1-16) antimicrobial
peptide bound to the thermus thermophilus 70s ribosome
. SNAP output
|
|
5f8l
|
transferase-RNA |
X-ray (2.812 Å) |
Shu B, Gong P |
(2016) "Structural
basis of viral RNA-dependent RNA polymerase catalysis
and translocation."
Proc.Natl.Acad.Sci.USA, 113,
E4005-E4014. doi: 10.1073/pnas.1602591113.
|
Enterovirus 71 polymerase elongation complex (c3s1
form) . SNAP output
|
|
5f8m
|
transferase-RNA |
X-ray (2.83 Å) |
Shu B, Gong P |
(2016) "Structural
basis of viral RNA-dependent RNA polymerase catalysis
and translocation."
Proc.Natl.Acad.Sci.USA, 113,
E4005-E4014. doi: 10.1073/pnas.1602591113.
|
Enterovirus 71 polymerase elongation complex (c3s4-5
form) . SNAP output
|
|
5f8n
|
transferase-RNA |
X-ray (2.484 Å) |
Shu B, Gong P |
(2016) "Structural
basis of viral RNA-dependent RNA polymerase catalysis
and translocation."
Proc.Natl.Acad.Sci.USA, 113,
E4005-E4014. doi: 10.1073/pnas.1602591113.
|
Enterovirus 71 polymerase elongation complex (c3s6
form) . SNAP output
|
|
5f98
|
hydrolase-RNA |
X-ray (3.28 Å) |
Devarkar SC, Wang C, Miller MT, Ramanathan A, Jiang
F, Khan AG, Patel SS, Marcotrigiano J |
(2016) "Structural
basis for m7G recognition and 2'-O-methyl
discrimination in capped RNAs by the innate immune
receptor RIG-I." Proc.Natl.Acad.Sci.USA,
113, 596-601. doi: 10.1073/pnas.1515152113.
|
Crystal structure of rig-i in complex with cap-0 RNA .
SNAP output
|
|
5f9f
|
hydrolase-RNA |
X-ray (2.601 Å) |
Devarkar SC, Wang C, Miller MT, Ramanathan A, Jiang
F, Khan AG, Patel SS, Marcotrigiano J |
(2016) "Structural
basis for m7G recognition and 2'-O-methyl
discrimination in capped RNAs by the innate immune
receptor RIG-I." Proc.Natl.Acad.Sci.USA,
113, 596-601. doi: 10.1073/pnas.1515152113.
|
Crystal structure of rig-i helicase-rd in complex with
24-mer blunt-end hairpin RNA . SNAP output
|
|
5f9h
|
hydrolase-RNA |
X-ray (3.1 Å) |
Devarkar SC, Wang C, Miller MT, Ramanathan A, Jiang
F, Khan AG, Patel SS, Marcotrigiano J |
(2016) "Structural
basis for m7G recognition and 2'-O-methyl
discrimination in capped RNAs by the innate immune
receptor RIG-I." Proc.Natl.Acad.Sci.USA,
113, 596-601. doi: 10.1073/pnas.1515152113.
|
Crystal structure of rig-i helicase-rd in complex with
24-mer 5' triphosphate hairpin RNA . SNAP output
|
|
5fci
|
ribosome |
X-ray (3.4 Å) |
Mailliot J, Garreau de Loubresse N, Yusupova G,
Meskauskas A, Dinman JD, Yusupov M |
(2016) "Crystal
Structures of the uL3 Mutant Ribosome: Illustration of
the Importance of Ribosomal Proteins for Translation
Efficiency." J.Mol.Biol.,
428, 2195-2202. doi: 10.1016/j.jmb.2016.02.013.
|
Structure of the vacant ul3 w255c mutant 80s yeast
ribosome . SNAP
output
|
|
5fcj
|
ribosome |
X-ray (3.1 Å) |
Mailliot J, Garreau de Loubresse N, Yusupova G,
Meskauskas A, Dinman JD, Yusupov M |
(2016) "Crystal
Structures of the uL3 Mutant Ribosome: Illustration of
the Importance of Ribosomal Proteins for Translation
Efficiency." J.Mol.Biol.,
428, 2195-2202. doi: 10.1016/j.jmb.2016.02.013.
|
Structure of the anisomycin-containing ul3 w255c mutant
80s yeast ribosome . SNAP output
|
|
5fdu
|
ribosome |
X-ray (2.9 Å) |
Seefeldt AC, Graf M, Perebaskine N, Nguyen F, Arenz
S, Mardirossian M, Scocchi M, Wilson DN, Innis CA |
(2016) "Structure
of the mammalian antimicrobial peptide Bac7(1-16) bound
within the exit tunnel of a bacterial ribosome."
Nucleic Acids Res., 44,
2429-2438. doi: 10.1093/nar/gkv1545.
|
Crystal structure of the metalnikowin i antimicrobial
peptide bound to the thermus thermophilus 70s ribosome
. SNAP output
|
|
5fdv
|
ribosome |
X-ray (2.8 Å) |
Seefeldt AC, Graf M, Perebaskine N, Nguyen F, Arenz
S, Mardirossian M, Scocchi M, Wilson DN, Innis CA |
(2016) "Structure
of the mammalian antimicrobial peptide Bac7(1-16) bound
within the exit tunnel of a bacterial ribosome."
Nucleic Acids Res., 44,
2429-2438. doi: 10.1093/nar/gkv1545.
|
Crystal structure of the pyrrhocoricin antimicrobial
peptide bound to the thermus thermophilus 70s ribosome
. SNAP output
|
|
5fj4
|
transcription |
X-ray (2.95 Å) |
Huang L, Wang J, Lilley DMJ |
(2016) "A
Critical Base Pair in K-Turns Determines the
Conformational Class Adopted, and Correlates with
Biological Function." Nucleic Acids Res.,
44, 5390. doi: 10.1093/NAR/GKW201.
|
Structure of the standard kink turn hmkt-7 as stem loop
bound with u1a and l7ae proteins . SNAP output
|
|
5flx
|
ribosome |
cryo-EM (3.9 Å) |
Yamamoto H, Collier M, Loerke J, Ismer J, Schmidt A,
Hilal T, Sprink T, Yamamoto K, Mielke T, Burger J, Shaikh
TR, Dabrowski M, Hildebrand PW, Scheerer P, Spahn CM |
(2015) "Molecular
Architecture of the Ribosome-Bound Hepatitis C Virus
Internal Ribosomal Entry Site RNA." Embo
J., 34, 3042. doi: 10.15252/EMBJ.201592469.
|
Mammalian 40s hcv-ires complex . SNAP output
|
|
5fmz
|
transcription |
X-ray (3.4 Å) |
Thierry E, Guilligay D, Kosinski J, Bock T, Gaudon S,
Round A, Pflug A, Hengrung N, El Omari K, Baudin F, Hart
DJ, Beck M, Cusack S |
(2016) "Influenza
Polymerase Can Adopt an Alternative Configuration
Involving a Radical Repacking of Pb2 Domains."
Mol.Cell, 61, 125. doi:
10.1016/J.MOLCEL.2015.11.016.
|
Crystal structure of influenza b polymerase with bound
5' vrna . SNAP
output
|
|
5fn1
|
virus |
cryo-EM (3.9 Å) |
Agirrezabala X, Mendez-Lopez E, Lasso G, Sanchez-Pina
MA, Aranda M, Valle M |
(2015) "The
near-atomic cryoEM structure of a flexible filamentous
plant virus shows homology of its coat protein with
nucleoproteins of animal viruses." Elife,
4, e11795. doi: 10.7554/eLife.11795.
|
Electron cryo-microscopy of filamentous flexible virus
pepmv (pepino mosaic virus) . SNAP output
|
|
5fvc
|
viral protein |
X-ray (4.17 Å) |
Renner M, Bertinelli M, Leyrat C, Paesen GC, Saraiva
de Oliveira LF, Huiskonen JT, Grimes JM |
(2016) "Nucleocapsid
assembly in pneumoviruses is regulated by
conformational switching of the N protein."
Elife, 5, e12627. doi:
10.7554/eLife.12627.
|
Structure of RNA-bound decameric hmpv nucleoprotein .
SNAP output
|
|
5g2x
|
transferase |
cryo-EM (3.8 Å) |
Qu G, Kaushal PS, Wang J, Shigematsu H, Piazza CL,
Agrawal RK, Belfort M, Wang H |
(2016) "Structure
of a Group II Intron in Complex with its Reverse
Transcriptase." Nat.Struct.Mol.Biol.,
23, 549. doi: 10.1038/NSMB.3220.
|
Structure a of group ii intron complexed with its
reverse transcriptase . SNAP output
|
|
5g4u
|
RNA-protein |
X-ray (2.65 Å) |
Huang L, Lilley DMJ |
(2016) "A
Quasi-Cyclic RNA Nano-Scale Molecular Object
Constructed Using Kink Turns." Nanoscale,
8, 15189. doi: 10.1039/C6NR05186C.
|
Association of three two-k-turn units based on kt-7
3bu,3nu, forming a triangular-shaped structure .
SNAP output
|
|
5g4v
|
DNA binding |
X-ray (2.87 Å) |
Huang L, Lilley DMJ |
(2016) "A
Quasi-Cyclic RNA Nano-Scale Molecular Object
Constructed Using Kink Turns." Nanoscale,
8, 15189. doi: 10.1039/C6NR05186C.
|
Association of four two-k-turn units based on kt-7
3bg,3nc, forming a square-shaped structure . SNAP output
|
|
5gad
|
ribosome |
cryo-EM (3.7 Å) |
Jomaa A, Boehringer D, Leibundgut M, Ban N |
(2016) "Structures
of the E. coli translating ribosome with SRP and its
receptor and with the translocon." Nat
Commun, 7, 10471. doi: 10.1038/ncomms10471.
|
Rnc-srp-sr complex early state . SNAP output
|
|
5gae
|
ribosome |
cryo-EM (3.33 Å) |
Jomaa A, Boehringer D, Leibundgut M, Ban N |
(2016) "Structures
of the E. coli translating ribosome with SRP and its
receptor and with the translocon." Nat
Commun, 7, 10471. doi: 10.1038/ncomms10471.
|
Rnc in complex with a translocating secyeg . SNAP output
|
|
5gaf
|
ribosome |
cryo-EM (4.3 Å) |
Jomaa A, Boehringer D, Leibundgut M, Ban N |
(2016) "Structures
of the E. coli translating ribosome with SRP and its
receptor and with the translocon." Nat
Commun, 7, 10471. doi: 10.1038/ncomms10471.
|
Rnc in complex with srp . SNAP output
|
|
5gag
|
ribosome |
cryo-EM (3.8 Å) |
Jomaa A, Boehringer D, Leibundgut M, Ban N |
(2016) "Structures
of the E. coli translating ribosome with SRP and its
receptor and with the translocon." Nat
Commun, 7, 10471. doi: 10.1038/ncomms10471.
|
Rnc in complex with srp-sr in the closed state .
SNAP output
|
|
5gah
|
ribosome |
cryo-EM (3.8 Å) |
Jomaa A, Boehringer D, Leibundgut M, Ban N |
(2016) "Structures
of the E. coli translating ribosome with SRP and its
receptor and with the translocon." Nat
Commun, 7, 10471. doi: 10.1038/ncomms10471.
|
Rnc in complex with srp with detached ng domain .
SNAP output
|
|
5gak
|
ribosome |
cryo-EM (3.88 Å) |
Schmidt C, Becker T, Heuer A, Braunger K,
Shanmuganathan V, Pech M, Berninghausen O, Wilson DN,
Beckmann R |
(2016) "Structure
of the hypusinylated eukaryotic translation factor
eIF-5A bound to the ribosome." Nucleic Acids
Res., 44, 1944-1951. doi:
10.1093/nar/gkv1517.
|
Yeast 60s ribosomal subunit with a-site trna, p-site
trna and eif-5a . SNAP
output
|
|
5gam
|
transcription |
cryo-EM (3.7 Å) |
Nguyen THD, Galej WP, Bai XC, Oubridge C, Scheres
SHW, Newman AJ, Nagai K |
(2016) "Cryo-EM
structure of the yeast U4/U6.U5 tri-snRNP at 3.7
Angstrom resolution." Nature,
530, 298-302. doi: 10.1038/nature16940.
|
Foot region of the yeast spliceosomal u4-u6.u5
tri-snrnp . SNAP
output
|
|
5gan
|
transcription |
cryo-EM (3.7 Å) |
Nguyen TH, Galej WP, Bai XC, Oubridge C, Newman AJ,
Scheres SH, Nagai K |
(2016) "Cryo-EM
structure of the yeast U4/U6.U5 tri-snRNP at 3.7
angstrom resolution." Nature,
530, 298-302. doi: 10.1038/nature16940.
|
The overall structure of the yeast spliceosomal
u4-u6.u5 tri-snrnp at 3.7 angstrom . SNAP output
|
|
5gao
|
transcription |
cryo-EM (4.2 Å) |
Nguyen TH, Galej WP, Bai XC, Oubridge C, Newman AJ,
Scheres SH, Nagai K |
(2016) "Cryo-EM
structure of the yeast U4/U6.U5 tri-snRNP at 3.7
angstrom resolution." Nature,
530, 298-302. doi: 10.1038/nature16940.
|
Head region of the yeast spliceosomal u4-u6.u5
tri-snrnp . SNAP
output
|
|
5gap
|
transcription |
cryo-EM (3.6 Å) |
Nguyen TH, Galej WP, Bai XC, Oubridge C, Newman AJ,
Scheres SH, Nagai K |
(2016) "Cryo-EM
structure of the yeast U4/U6.U5 tri-snRNP at 3.7
angstrom resolution." Nature,
530, 298-302. doi: 10.1038/nature16940.
|
Body region of the u4-u6.u5 tri-snrnp . SNAP output
|
|
5gin
|
transferase-RNA |
X-ray (3.308 Å) |
Yang Z, Lin J, Ye K |
(2016) "Box C/D
guide RNAs recognize a maximum of 10 nt of
substrates." Proc.Natl.Acad.Sci.USA,
113, 10878-10883. doi: 10.1073/pnas.1604872113.
|
Crystal structure of box c-d rnp with 12 nt guide
regions and 9 nt substrates . SNAP output
|
|
5gio
|
transferase-RNA |
X-ray (3.604 Å) |
Yang Z, Lin J, Ye K |
(2016) "Box C/D
guide RNAs recognize a maximum of 10 nt of
substrates." Proc.Natl.Acad.Sci.USA,
113, 10878-10883. doi: 10.1073/pnas.1604872113.
|
Crystal structure of box c-d rnp with 12 nt guide
regions and 13 nt substrates . SNAP output
|
|
5gip
|
transferase-RNA |
X-ray (3.129 Å) |
Yang Z, Lin J, Ye K |
(2016) "Box C/D
guide RNAs recognize a maximum of 10 nt of
substrates." Proc.Natl.Acad.Sci.USA,
113, 10878-10883. doi: 10.1073/pnas.1604872113.
|
Crystal structure of box c-d rnp with 13 nt guide
regions and 11 nt substrates . SNAP output
|
|
5gjb
|
hydrolase-RNA |
X-ray (1.702 Å) |
Tian HL, Ji XY, Yang XY, Zhang ZX, Lu ZK, Yang KL,
Chen C, Zhao Q, Chi H, Mu ZY, Xie W, Wang ZF, Lou HQ,
Yang HT, Rao ZH |
(2016) "Structural
basis of Zika virus helicase in recognizing its
substrates." Protein Cell,
7, 562-570. doi: 10.1007/s13238-016-0293-2.
|
Zika virus ns3 helicase in complex with ssrna .
SNAP output
|
|
5gm6
|
RNA binding protein-RNA |
cryo-EM (3.5 Å) |
Yan C, Wan R, Bai R, Huang G, Shi Y |
(2016) "Structure
of a yeast activated spliceosome at 3.5 angstrom
resolution." Science,
353, 904-911. doi: 10.1126/science.aag0291.
|
cryo-EM structure of the activated spliceosome (bact
complex) at 3.5 angstrom resolution . SNAP output
|
|
5gmf
|
immune system-RNA |
X-ray (2.5 Å) |
Zhang Z, Ohto U, Shibata T, Krayukhina E, Taoka M,
Yamauchi Y, Tanji H, Isobe T, Uchiyama S, Miyake K,
Shimizu T |
(2016) "Structural
Analysis Reveals that Toll-like Receptor 7 Is a Dual
Receptor for Guanosine and Single-Stranded RNA."
Immunity, 45, 737-748. doi:
10.1016/j.immuni.2016.09.011.
|
Crystal structure of monkey tlr7 in complex with
guanosine and polyu . SNAP output
|
|
5gmg
|
immune system-RNA |
X-ray (2.6 Å) |
Zhang Z, Ohto U, Shibata T, Krayukhina E, Taoka M,
Yamauchi Y, Tanji H, Isobe T, Uchiyama S, Miyake K,
Shimizu T |
(2016) "Structural
Analysis Reveals that Toll-like Receptor 7 Is a Dual
Receptor for Guanosine and Single-Stranded RNA."
Immunity, 45, 737-748. doi:
10.1016/j.immuni.2016.09.011.
|
Crystal structure of monkey tlr7 in complex with
loxoribine and polyu . SNAP output
|
|
5gmk
|
RNA binding protein-RNA |
cryo-EM (3.4 Å) |
Wan R, Yan C, Bai R, Huang G, Shi Y |
(2016) "Structure
of a yeast catalytic step I spliceosome at 3.4 angstrom
resolution." Science,
353, 895-904. doi: 10.1126/science.aag2235.
|
cryo-EM structure of the catalytic step i spliceosome
(c complex) at 3.4 angstrom resolution . SNAP output
|
|
5guh
|
hydrolase-RNA |
X-ray (2.4 Å) |
Matsumoto N, Nishimasu H, Sakakibara K, Nishida KM,
Hirano T, Ishitani R, Siomi H, Siomi MC, Nureki O |
(2016) "Crystal
Structure of Silkworm PIWI-Clade Argonaute Siwi Bound
to piRNA." Cell, 167,
484-497.e9. doi: 10.1016/j.cell.2016.09.002.
|
Crystal structure of silkworm piwi-clade argonaute siwi
bound to pirna . SNAP
output
|
|
5gxh
|
RNA binding protein-RNA |
X-ray (1.8 Å) |
Xu C, Ishikawa H, Izumikawa K, Li L, He H, Nobe Y,
Yamauchi Y, Shahjee HM, Wu X-H, Yu Y-T, Isobe T,
Takahashi N, Min J |
(2016) "Structural
insights into Gemin5-guided selection of pre-snRNAs for
snRNP assembly." Genes Dev.,
30, 2376-2390. doi: 10.1101/gad.288340.116.
|
The structure of the gemin5 wd40 domain with aauuuuug .
SNAP output
|
|
5gxi
|
RNA binding protein-RNA |
X-ray (1.85 Å) |
Xu C, Ishikawa H, Izumikawa K, Li L, He H, Nobe Y,
Yamauchi Y, Shahjee HM, Wu X-H, Yu Y-T, Isobe T,
Takahashi N, Min J |
(2016) "Structural
insights into Gemin5-guided selection of pre-snRNAs for
snRNP assembly." Genes Dev.,
30, 2376-2390. doi: 10.1101/gad.288340.116.
|
Structure of the gemin5 wd40 domain in complex with
aauuuuugag . SNAP
output
|
|
5h0r
|
transferase-RNA |
cryo-EM (3.9 Å) |
Li X, Zhou N, Chen W, Zhu B, Wang X, Xu B, Wang J,
Liu H, Cheng L |
(2017) "Near-Atomic
Resolution Structure Determination of a Cypovirus
Capsid and Polymerase Complex Using Cryo-EM at
200kV." J. Mol. Biol.,
429, 79-87. doi: 10.1016/j.jmb.2016.11.025.
|
RNA dependent RNA polymerase ,vp4,dsrna . SNAP output
|
|
5h1k
|
splicing-RNA |
X-ray (1.9 Å) |
Jin W, Wang Y, Liu CP, Yang N, Jin M, Cong Y, Wang M,
Xu RM |
(2016) "Structural
basis for snRNA recognition by the double-WD40 repeat
domain of Gemin5." Genes Dev.,
30, 2391-2403. doi: 10.1101/gad.291377.116.
|
Crystal structure of wd40 repeat domains of gemin5 in
complex with 13-nt u4 snrna fragment . SNAP output
|
|
5h1l
|
splicing-RNA |
X-ray (2.1 Å) |
Jin W, Wang Y, Liu CP, Yang N, Jin M, Cong Y, Wang M,
Xu RM |
(2016) "Structural
basis for snRNA recognition by the double-WD40 repeat
domain of Gemin5." Genes Dev.,
30, 2391-2403. doi: 10.1101/gad.291377.116.
|
Crystal structure of wd40 repeat domains of gemin5 in
complex with 7-nt u4 snrna fragment . SNAP output
|
|
5h1s
|
ribosome |
cryo-EM (3.5 Å) |
Ahmed T, Yin Z, Bhushan S |
(2016) "Cryo-EM
structure of the large subunit of the spinach
chloroplast ribosome." Sci Rep,
6, 35793. doi: 10.1038/srep35793.
|
Structure of the large subunit of the chloro-ribosome .
SNAP output
|
|
5h3u
|
RNA binding protein-RNA |
X-ray (2.499 Å) |
Tang X, Bharath SR, Piao S, Tan VQ, Bowler MW, Song
H |
(2016) "Structural
basis for specific recognition of pre-snRNA by
Gemin5." Cell Res., 26,
1353-1356. doi: 10.1038/cr.2016.133.
|
Sm RNA bound to gemin5-wd . SNAP output
|
|
5h4p
|
ribosome |
cryo-EM (3.07 Å) |
Ma C, Wu S, Li N, Chen Y, Yan K, Li Z, Zheng L, Lei
J, Woolford JL, Gao N |
(2017) "Structural
snapshot of cytoplasmic pre-60S ribosomal particles
bound by Nmd3, Lsg1, Tif6 and Reh1." Nat.
Struct. Mol. Biol., 24, 214-220.
doi: 10.1038/nsmb.3364.
|
Structural snapshot of cytoplasmic pre-60s ribosomal
particles bound with nmd3, lsg1, tif6 and reh1 .
SNAP output
|
|
5h5u
|
ribosome |
cryo-EM (3.01 Å) |
Ma C, Kurita D, Li N, Chen Y, Himeno H, Gao N |
(2017) "Mechanistic
insights into the alternative translation termination
by ArfA and RF2." Nature,
541, 550-553. doi: 10.1038/nature20822.
|
Mechanistic insights into the alternative translation
termination by arfa and rf2 . SNAP output
|
|
5hab
|
hydrolase |
X-ray (2.3 Å) |
Zheng X, Feng N, Li DF, Li J, Dong XZ |
"Molecular insights into catalysis and processive
exonucleolytic mechanisms of prokaryotic RNase J
revealing striking parallels with that of eukaryotic
Xrn1." |
Crystal structure of mpy-rnase j (mutant h84a), an
archaeal rnase j from methanolobus psychrophilus r15,
complex with RNA . SNAP
output
|
|
5hau
|
ribosome-antibiotic |
X-ray (3.0 Å) |
Gagnon MG, Roy RN, Lomakin IB, Florin T, Mankin AS,
Steitz TA |
(2016) "Structures
of proline-rich peptides bound to the ribosome reveal a
common mechanism of protein synthesis inhibition."
Nucleic Acids Res., 44,
2439-2450. doi: 10.1093/nar/gkw018.
|
Crystal structure of antimicrobial peptide bac7(1-19)
bound to the thermus thermophilus 70s ribosome .
SNAP output
|
|
5hc9
|
transferase |
X-ray (2.9 Å) |
Yamashita S, Tomita K |
(2016) "Mechanism
of 3'-Matured tRNA Discrimination from 3'-Immature tRNA
by Class-II CCA-Adding Enzyme." Structure,
24, 918-925. doi: 10.1016/j.str.2016.03.022.
|
Thermotoga maritima cca-adding enzyme complexed with
trna_cca . SNAP
output
|
|
5hcp
|
ribosome-antibiotic |
X-ray (2.894 Å) |
Gagnon MG, Roy RN, Lomakin IB, Florin T, Mankin AS,
Steitz TA |
(2016) "Structures
of proline-rich peptides bound to the ribosome reveal a
common mechanism of protein synthesis inhibition."
Nucleic Acids Res., 44,
2439-2450. doi: 10.1093/nar/gkw018.
|
Crystal structure of antimicrobial peptide metalnikowin
bound to the thermus thermophilus 70s ribosome .
SNAP output
|
|
5hcq
|
ribosome-antibiotic |
X-ray (2.801 Å) |
Gagnon MG, Roy RN, Lomakin IB, Florin T, Mankin AS,
Steitz TA |
(2016) "Structures
of proline-rich peptides bound to the ribosome reveal a
common mechanism of protein synthesis inhibition."
Nucleic Acids Res., 44,
2439-2450. doi: 10.1093/nar/gkw018.
|
Crystal structure of antimicrobial peptide oncocin
d15-19 bound to the thermus thermophilus 70s ribosome .
SNAP output
|
|
5hcr
|
ribosome-antibiotic |
X-ray (2.8 Å) |
Gagnon MG, Roy RN, Lomakin IB, Florin T, Mankin AS,
Steitz TA |
(2016) "Structures
of proline-rich peptides bound to the ribosome reveal a
common mechanism of protein synthesis inhibition."
Nucleic Acids Res., 44,
2439-2450. doi: 10.1093/nar/gkw018.
|
Crystal structure of antimicrobial peptide oncocin 10wt
bound to the thermus thermophilus 70s ribosome .
SNAP output
|
|
5hd1
|
ribosome-antibiotic |
X-ray (2.7 Å) |
Gagnon MG, Roy RN, Lomakin IB, Florin T, Mankin AS,
Steitz TA |
(2016) "Structures
of proline-rich peptides bound to the ribosome reveal a
common mechanism of protein synthesis inhibition."
Nucleic Acids Res., 44,
2439-2450. doi: 10.1093/nar/gkw018.
|
Crystal structure of antimicrobial peptide
pyrrhocoricin bound to the thermus thermophilus 70s
ribosome . SNAP
output
|
|
5hjz
|
hydrolase-RNA |
X-ray (1.976 Å) |
Yen TJ, Brennan RG |
"Structure of M. tuberculosis MazF-mt1 (Rv2801c) in
complex with RNA." |
Structure of m. tuberculosis mazf-mt1 (rv2801c) in
complex with RNA . SNAP
output
|
|
5hkv
|
ribosome |
X-ray (3.66 Å) |
Matzov D, Eyal Z, Benhamou RI, Shalev-Benami M,
Halfon Y, Krupkin M, Zimmerman E, Rozenberg H, Bashan A,
Fridman M, Yonath A |
(2017) "Structural
insights of lincosamides targeting the ribosome of
Staphylococcus aureus." Nucleic Acids
Res., 45, 10284-10292. doi:
10.1093/nar/gkx658.
|
The crystal structure of the large ribosomal subunit of
staphylococcus aureus in complex with lincomycin .
SNAP output
|
|
5hl7
|
ribosome |
X-ray (3.55 Å) |
Eyal Z, Matzov D, Krupkin M, Paukner S, Riedl R,
Rozenberg H, Zimmerman E, Bashan A, Yonath A |
(2016) "A novel
pleuromutilin antibacterial compound, its binding mode
and selectivity mechanism." Sci Rep,
6, 39004. doi: 10.1038/srep39004.
|
The crystal structure of the large ribosomal subunit of
staphylococcus aureus in complex with lefamulin .
SNAP output
|
|
5ho4
|
RNA binding protein-RNA |
X-ray (1.85 Å) |
Wu BX, Su SC, Patil DP, Liu H, Gan JH, Jaffrey SR, Ma
JB |
(2018) "Molecular
basis for the specific and multivariant recognitions of
RNA substrates by human hnRNP A2/B1." Nat
Commun, 9, 420. doi: 10.1038/s41467-017-02770-z.
|
Crystal structure of hnrnpa2b1 in complex with 10-mer
RNA . SNAP output
|
|
5hp2
|
hydrolase-RNA |
X-ray (2.983 Å) |
Matthews MM, Thomas JM, Zheng Y, Tran K, Phelps KJ,
Scott AI, Havel J, Fisher AJ, Beal PA |
(2016) "Structures
of human ADAR2 bound to dsRNA reveal base-flipping
mechanism and basis for site selectivity."
Nat.Struct.Mol.Biol., 23,
426-433. doi: 10.1038/nsmb.3203.
|
Human adenosine deaminase acting on dsrna (adar2) bound
to dsrna sequence derived from s. cerevisiae bdf2 gene
with au basepair at reaction site . SNAP output
|
|
5hp3
|
hydrolase-RNA |
X-ray (3.091 Å) |
Matthews MM, Thomas JM, Zheng Y, Tran K, Phelps KJ,
Scott AI, Havel J, Fisher AJ, Beal PA |
(2016) "Structures
of human ADAR2 bound to dsRNA reveal base-flipping
mechanism and basis for site selectivity."
Nat.Struct.Mol.Biol., 23,
426-433. doi: 10.1038/nsmb.3203.
|
Human adenosine deaminase acting on dsrna (adar2) bound
to dsrna sequence derived from s. cerevisiae bdf2 gene
with ac mismatch at reaction site . SNAP output
|
|
5hr6
|
transferase-RNA |
X-ray (2.88 Å) |
Schwalm EL, Grove TL, Booker SJ, Boal AK |
(2016) "Crystallographic
capture of a radical S-adenosylmethionine enzyme in the
act of modifying tRNA." Science,
352, 309-312. doi: 10.1126/science.aad5367.
|
X-ray crystal structure of c118a rlmn with cross-linked
trna purified from escherichia coli . SNAP output
|
|
5hr7
|
oxidoreductase-RNA |
X-ray (2.4 Å) |
Schwalm EL, Grove TL, Booker SJ, Boal AK |
(2016) "Crystallographic
capture of a radical S-adenosylmethionine enzyme in the
act of modifying tRNA." Science,
352, 309-312. doi: 10.1126/science.aad5367.
|
X-ray crystal structure of c118a rlmn from escherichia
coli with cross-linked in vitro transcribed trna .
SNAP output
|
|
5hsw
|
hydrolase |
X-ray (3.3 Å) |
Lee H, Patschull AOM, Bagneris C, Ryan H, Sanderson
CM, Ebrahimi B, Nobeli I, Barrett TE |
(2017) "KSHV SOX
mediated host shutoff: the molecular mechanism
underlying mRNA transcript processing." Nucleic
Acids Res., 45, 4756-4767. doi:
10.1093/nar/gkw1340.
|
Kshv sox RNA complex . SNAP output
|
|
5i4l
|
ribosome |
X-ray (3.1 Å) |
Prokhorova IV, Akulich KA, Makeeva DS, Osterman IA,
Skvortsov DA, Sergiev PV, Dontsova OA, Yusupova G,
Yusupov MM, Dmitriev SE |
(2016) "Amicoumacin
A induces cancer cell death by targeting the eukaryotic
ribosome." Sci Rep, 6,
27720. doi: 10.1038/srep27720.
|
Crystal structure of amicoumacin a bound to the yeast
80s ribosome . SNAP
output
|
|
5i8q
|
hydrolase |
X-ray (4.2 Å) |
He Y, Staley JP, Andersen GR, Nielsen KH |
(2017) "Structure
of the DEAH/RHA ATPase Prp43p bound to RNA implicates a
pair of hairpins and motif Va in translocation along
RNA." RNA, 23, 1110-1124.
doi: 10.1261/rna.060954.117.
|
S. cerevisiae prp43 in complex with RNA and adpnp .
SNAP output
|
|
5i9d
|
RNA binding protein-RNA |
X-ray (2.596 Å) |
Shen C, Zhang D, Guan Z, Liu Y, Yang Z, Yang Y, Wang
X, Wang Q, Zhang Q, Fan S, Zou T, Yin P |
(2016) "Structural
basis for specific single-stranded RNA recognition by
designer pentatricopeptide repeat proteins."
Nat Commun, 7, 11285. doi:
10.1038/ncomms11285.
|
Crystal structure of designed pentatricopeptide repeat
protein dppr-u8a2 in complex with its target RNA u8a2 .
SNAP output
|
|
5i9f
|
RNA binding protein-RNA |
X-ray (2.194 Å) |
Shen C, Zhang D, Guan Z, Liu Y, Yang Z, Yang Y, Wang
X, Wang Q, Zhang Q, Fan S, Zou T, Yin P |
(2016) "Structural
basis for specific single-stranded RNA recognition by
designer pentatricopeptide repeat proteins."
Nat Commun, 7, 11285. doi:
10.1038/ncomms11285.
|
Crystal structure of designed pentatricopeptide repeat
protein dppr-u10 in complex with its target RNA u10 .
SNAP output
|
|
5i9h
|
RNA binding protein-RNA |
X-ray (2.504 Å) |
Shen C, Zhang D, Guan Z, Liu Y, Yang Z, Yang Y, Wang
X, Wang Q, Zhang Q, Fan S, Zou T, Yin P |
(2016) "Structural
basis for specific single-stranded RNA recognition by
designer pentatricopeptide repeat proteins."
Nat Commun, 7, 11285. doi:
10.1038/ncomms11285.
|
Crystal structure of designed pentatricopeptide repeat
protein dppr-u8g2 in complex with its target RNA u8g2 .
SNAP output
|
|
5ib7
|
translation |
X-ray (2.99 Å) |
Rozov A, Westhof E, Yusupov M, Yusupova G |
(2016) "The
ribosome prohibits the GU wobble geometry at the first
position of the codon-anticodon helix." Nucleic
Acids Res., 44, 6434-6441. doi:
10.1093/nar/gkw431.
|
Structure of t. thermophilus 70s ribosome complex with
mrna, trnafmet, near-cognate trnalys with u-g mismatch
in the a-site and antibiotic paromomycin . SNAP output
|
|
5ib8
|
ribosome |
X-ray (3.13 Å) |
Rozov A, Westhof E, Yusupov M, Yusupova G |
(2016) "The
ribosome prohibits the GU wobble geometry at the first
position of the codon-anticodon helix." Nucleic
Acids Res., 44, 6434-6441. doi:
10.1093/nar/gkw431.
|
Structure of t. thermophilus 70s ribosome complex with
mrna, trnafmet and near-cognate trnalys with u-g
mismatch in the a-site . SNAP output
|
|
5ibb
|
ribosome |
X-ray (2.96 Å) |
Rozov A, Westhof E, Yusupov M, Yusupova G |
(2016) "The
ribosome prohibits the GU wobble geometry at the first
position of the codon-anticodon helix." Nucleic
Acids Res., 44, 6434-6441. doi:
10.1093/nar/gkw431.
|
Structure of t. thermophilus 70s ribosome complex with
mrna, trnafmet and cognate trnaval in the a-site .
SNAP output
|
|
5id6
|
hydrolase |
X-ray (2.382 Å) |
Dong D, Ren K, Qiu X, Zheng J, Guo M, Guan X, Liu H,
Li N, Zhang B, Yang D, Ma C, Wang S, Wu D, Ma Y, Fan S,
Wang J, Gao N, Huang Z |
(2016) "The
crystal structure of Cpf1 in complex with CRISPR
RNA." Nature, 532,
522-526. doi: 10.1038/nature17944.
|
Structure of cpf1-RNA complex . SNAP output
|
|
5imq
|
ribosome |
cryo-EM (3.8 Å) |
Kumar V, Ero R, Ahmed T, Goh KJ, Zhan Y, Bhushan S,
Gao YG |
(2016) "Structure
of the GTP Form of Elongation Factor 4 (EF4) Bound to
the Ribosome." J.Biol.Chem.,
291, 12943-12950. doi: 10.1074/jbc.M116.725945.
|
Structure of ribosome bound to cofactor at 3.8 angstrom
resolution . SNAP
output
|
|
5imr
|
ribosome |
cryo-EM (5.7 Å) |
Kumar V, Ero R, Ahmed T, Goh KJ, Zhan Y, Bhushan S,
Gao YG |
(2016) "Structure
of the GTP Form of Elongation Factor 4 (EF4) Bound to
the Ribosome." J.Biol.Chem.,
291, 12943-12950. doi: 10.1074/jbc.M116.725945.
|
Structure of ribosome bound to cofactor at 5.7 angstrom
resolution . SNAP
output
|
|
5ip2
|
viral protein-RNA |
X-ray (3.3 Å) |
Komoda K, Narita M, Yamashita K, Tanaka I, Yao M |
(2017) "Asymmetric
Trimeric Ring Structure of the Nucleocapsid Protein of
Tospovirus." J. Virol.,
91. doi: 10.1128/JVI.01002-17.
|
Tomato spotted wilt tospovirus nucleocapsid
protein-ssrna complex . SNAP output
|
|
5iqr
|
ribosome |
cryo-EM (3.0 Å) |
Brown A, Fernandez IS, Gordiyenko Y, Ramakrishnan
V |
(2016) "Ribosome-dependent
activation of stringent control." Nature,
534, 277-280. doi: 10.1038/nature17675.
|
Structure of rela bound to the 70s ribosome . SNAP output
|
|
5it8
|
ribosome |
X-ray (3.12 Å) |
Cocozaki AI, Altman RB, Huang J, Buurman ET,
Kazmirski SL, Doig P, Prince DB, Blanchard SC, Cate JH,
Ferguson AD |
(2016) "Resistance
mutations generate divergent antibiotic susceptibility
profiles against translation inhibitors."
Proc.Natl.Acad.Sci.USA, 113,
8188-8193. doi: 10.1073/pnas.1605127113.
|
High-resolution structure of the escherichia coli
ribosome . SNAP
output
|
|
5iwa
|
translation |
X-ray (3.5 Å) |
Fabbretti A, Schedlbauer A, Brandi L, Kaminishi T,
Giuliodori AM, Garofalo R, Ochoa-Lizarralde B, Takemoto
C, Yokoyama S, Connell SR, Gualerzi CO, Fucini P |
(2016) "Inhibition
of translation initiation complex formation by GE81112
unravels a 16S rRNA structural switch involved in
P-site decoding." Proc.Natl.Acad.Sci.USA,
113, E2286-E2295. doi: 10.1073/pnas.1521156113.
|
Crystal structure of the 30s ribosomal subunit from
thermus thermophilus in complex with the ge81112
peptide antibiotic . SNAP output
|
|
5j0m
|
viral protein |
NMR |
Borkar AN, Bardaro MF, Camilloni C, Aprile FA, Varani
G, Vendruscolo M |
(2016) "Structure
of a low-population binding intermediate in protein-RNA
recognition." Proc.Natl.Acad.Sci.USA,
113, 7171-7176. doi: 10.1073/pnas.1521349113.
|
Ground state sampled during rdc restrained
replica-averaged metadynamics (ram) simulations of the
hiv-1 tar complexed with cyclic peptide mimetic of tat
. SNAP output
|
|
5j1o
|
viral protein |
NMR |
Borkar AN, Bardaro MF, Camilloni C, Aprile FA, Varani
G, Vendruscolo M |
(2016) "Structure
of a low-population binding intermediate in protein-RNA
recognition." Proc.Natl.Acad.Sci.USA,
113, 7171-7176. doi: 10.1073/pnas.1521349113.
|
Excited state (bound-like) sampled during rdc
restrained replica-averaged metadynamics (ram)
simulations of the hiv-1 tar complexed with cyclic
peptide mimetic of tat . SNAP output
|
|
5j2w
|
viral protein |
NMR |
Borkar AN, Bardaro MF, Camilloni C, Aprile FA, Varani
G, Vendruscolo M |
(2016) "Structure
of a low-population binding intermediate in protein-RNA
recognition." Proc.Natl.Acad.Sci.USA,
113, 7171-7176. doi: 10.1073/pnas.1521349113.
|
Intermediate state lying on the pathway of release of
tat from hiv-1 tar. . SNAP output
|
|
5j30
|
ribosome |
X-ray (3.2 Å) |
Pierson WE, Hoffer ED, Keedy HE, Simms CL, Dunham CM,
Zaher HS |
(2016) "Uniformity
of Peptide Release Is Maintained by Methylation of
Release Factors." Cell Rep,
17, 11-18. doi: 10.1016/j.celrep.2016.08.085.
|
Thermus thermophilus 70s termination complex containing
e. coli rf1 . SNAP
output
|
|
5j3c
|
ribosome |
X-ray (3.04 Å) |
Pierson WE, Hoffer ED, Keedy HE, Simms CL, Dunham CM,
Zaher HS |
(2016) "Uniformity
of Peptide Release Is Maintained by Methylation of
Release Factors." Cell Rep,
17, 11-18. doi: 10.1016/j.celrep.2016.08.085.
|
Thermus thermophilus 70s termination complex containing
e. coli rf1 . SNAP
output
|
|
5j4b
|
ribosome |
X-ray (2.6 Å) |
Melnikov SV, Soll D, Steitz TA, Polikanov YS |
(2016) "Insights
into RNA binding by the anticancer drug cisplatin from
the crystal structure of cisplatin-modified
ribosome." Nucleic Acids Res.,
44, 4978-4987. doi: 10.1093/nar/gkw246.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with cisplatin (co-crystallized)
and bound to mrna and a-, p- and e-site trnas at 2.6a
resolution . SNAP
output
|
|
5j4c
|
ribosome |
X-ray (2.8 Å) |
Melnikov SV, Soll D, Steitz TA, Polikanov YS |
(2016) "Insights
into RNA binding by the anticancer drug cisplatin from
the crystal structure of cisplatin-modified
ribosome." Nucleic Acids Res.,
44, 4978-4987. doi: 10.1093/nar/gkw246.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with cisplatin (soaked) and bound
to mrna and a-, p- and e-site trnas at 2.8a resolution
. SNAP output
|
|
5j4d
|
ribosome |
X-ray (3.1 Å) |
Svidritskiy E, Madireddy R, Korostelev AA |
(2016) "Structural
Basis for Translation Termination on a Pseudouridylated
Stop Codon." J.Mol.Biol.,
428, 2228-2236. doi: 10.1016/j.jmb.2016.04.018.
|
E. coli release factor 1 bound to the 70s ribosome in
response to a pseudouridylated stop codon . SNAP output
|
|
5j5b
|
ribosome-antibiotic |
X-ray (2.8 Å) |
Cocozaki AI, Altman RB, Huang J, Buurman ET,
Kazmirski SL, Doig P, Prince DB, Blanchard SC, Cate JH,
Ferguson AD |
(2016) "Resistance
mutations generate divergent antibiotic susceptibility
profiles against translation inhibitors."
Proc.Natl.Acad.Sci.USA, 113,
8188-8193. doi: 10.1073/pnas.1605127113.
|
Structure of the wt e coli ribosome bound to
tetracycline . SNAP
output
|
|
5j7l
|
ribosome-antibiotic |
X-ray (3.0 Å) |
Cocozaki AI, Altman RB, Huang J, Buurman ET,
Kazmirski SL, Doig P, Prince DB, Blanchard SC, Cate JH,
Ferguson AD |
(2016) "Resistance
mutations generate divergent antibiotic susceptibility
profiles against translation inhibitors."
Proc.Natl.Acad.Sci.USA, 113,
8188-8193. doi: 10.1073/pnas.1605127113.
|
Structure of the 70s e coli ribosome with the u1052g
mutation in the 16s rrna bound to tetracycline .
SNAP output
|
|
5j88
|
ribosome-antibiotic |
X-ray (3.32 Å) |
Cocozaki AI, Altman RB, Huang J, Buurman ET,
Kazmirski SL, Doig P, Prince DB, Blanchard SC, Cate JH,
Ferguson AD |
(2016) "Resistance
mutations generate divergent antibiotic susceptibility
profiles against translation inhibitors."
Proc.Natl.Acad.Sci.USA, 113,
8188-8193. doi: 10.1073/pnas.1605127113.
|
Structure of the e coli 70s ribosome with the u1060a
mutation in 16s rrna . SNAP output
|
|
5j8a
|
ribosome-antibiotic |
X-ray (3.1 Å) |
Cocozaki AI, Altman RB, Huang J, Buurman ET,
Kazmirski SL, Doig P, Prince DB, Blanchard SC, Cate JH,
Ferguson AD |
(2016) "Resistance
mutations generate divergent antibiotic susceptibility
profiles against translation inhibitors."
Proc.Natl.Acad.Sci.USA, 113,
8188-8193. doi: 10.1073/pnas.1605127113.
|
Structure of the e coli 70s ribosome with the u1052g
mutation in 16s rrna bound to tigecycline . SNAP output
|
|
5j8b
|
ribosome |
X-ray (2.6 Å) |
Gagnon MG, Lin J, Steitz TA |
(2016) "Elongation
factor 4 remodels the A-site tRNA on the ribosome."
Proc.Natl.Acad.Sci.USA, 113,
4994-4999. doi: 10.1073/pnas.1522932113.
|
Crystal structure of elongation factor 4 (ef-4-lepa) in
complex with gdpcp bound to the thermus thermophilus
70s ribosome . SNAP
output
|
|
5j91
|
ribosome-antibiotic |
X-ray (2.96 Å) |
Cocozaki AI, Altman RB, Huang J, Buurman ET,
Kazmirski SL, Doig P, Prince DB, Blanchard SC, Cate JH,
Ferguson AD |
(2016) "Resistance
mutations generate divergent antibiotic susceptibility
profiles against translation inhibitors."
Proc.Natl.Acad.Sci.USA, 113,
8188-8193. doi: 10.1073/pnas.1605127113.
|
Structure of the wild-type 70s e coli ribosome bound to
tigecycline . SNAP
output
|
|
5jaj
|
RNA binding protein |
X-ray (1.5 Å) |
Uchikawa E, Lethier M, Malet H, Brunel J, Gerlier D,
Cusack S |
(2016) "Structural
Analysis of dsRNA Binding to Anti-viral Pattern
Recognition Receptors LGP2 and MDA5."
Mol.Cell, 62, 586-602. doi:
10.1016/j.molcel.2016.04.021.
|
Structure of chicken lgp2 witha 5'p 10-mer dsrna and
adp-alf4-mg. . SNAP
output
|
|
5jb2
|
immune system |
X-ray (2.2 Å) |
Uchikawa E, Lethier M, Malet H, Brunel J, Gerlier D,
Cusack S |
(2016) "Structural
Analysis of dsRNA Binding to Anti-viral Pattern
Recognition Receptors LGP2 and MDA5."
Mol.Cell, 62, 586-602. doi:
10.1016/j.molcel.2016.04.021.
|
Crystal structure of chicken lgp2 with 5'ppp 10-mer
dsrna and adp-alf4-mg2+ at 2.2 Å resolution. . SNAP output
|
|
5jb3
|
translation |
cryo-EM (5.34 Å) |
Coureux PD, Lazennec-Schurdevin C, Monestier A,
Larquet E, Cladiere L, Klaholz BP, Schmitt E, Mechulam
Y |
(2016) "Cryo-EM
study of start codon selection during archaeal
translation initiation." Nat Commun,
7, 13366. doi: 10.1038/ncomms13366.
|
cryo-EM structure of a full archaeal ribosomal
translation initiation complex in the p-remote
conformation . SNAP
output
|
|
5jbg
|
immune system |
X-ray (2.0 Å) |
Uchikawa E, Lethier M, Malet H, Brunel J, Gerlier D,
Cusack S |
(2016) "Structural
Analysis of dsRNA Binding to Anti-viral Pattern
Recognition Receptors LGP2 and MDA5."
Mol.Cell, 62, 586-602. doi:
10.1016/j.molcel.2016.04.021.
|
Crystal structure of chicken lgp2 with 5'ppp 26-mer
hairpin RNA with 3' gg overhang and adp-alf4-mg2+ at
2.0 Å resolution. . SNAP
output
|
|
5jbh
|
transcription |
cryo-EM (5.34 Å) |
Coureux PD, Lazennec-Schurdevin C, Monestier A,
Larquet E, Cladiere L, Klaholz BP, Schmitt E, Mechulam
Y |
(2016) "Cryo-EM
study of start codon selection during archaeal
translation initiation." Nat Commun,
7, 13366. doi: 10.1038/ncomms13366.
|
cryo-EM structure of a full archaeal ribosomal
translation initiation complex in the p-in conformation
. SNAP output
|
|
5jbj
|
immune system |
X-ray (3.58 Å) |
Uchikawa E, Lethier M, Malet H, Brunel J, Gerlier D,
Cusack S |
(2016) "Structural
Analysis of dsRNA Binding to Anti-viral Pattern
Recognition Receptors LGP2 and MDA5."
Mol.Cell, 62, 586-602. doi:
10.1016/j.molcel.2016.04.021.
|
Crystal structure of chicken lgp2 with 5'p 12-mer dsrna
at 3.6 Å resolution . SNAP output
|
|
5jc3
|
immune system |
X-ray (2.6 Å) |
Uchikawa E, Lethier M, Malet H, Brunel J, Gerlier D,
Cusack S |
(2016) "Structural
Analysis of dsRNA Binding to Anti-viral Pattern
Recognition Receptors LGP2 and MDA5."
Mol.Cell, 62, 586-602. doi:
10.1016/j.molcel.2016.04.021.
|
Crystal structure of chicken mda5 with 5'p 10-mer dsrna
and adp-mg2+ at 2.6 Å resolution (monoclinic form,
twinned). . SNAP
output
|
|
5jc7
|
immune system |
X-ray (2.75 Å) |
Uchikawa E, Lethier M, Malet H, Brunel J, Gerlier D,
Cusack S |
(2016) "Structural
Analysis of dsRNA Binding to Anti-viral Pattern
Recognition Receptors LGP2 and MDA5."
Mol.Cell, 62, 586-602. doi:
10.1016/j.molcel.2016.04.021.
|
Crystal structure of chicken mda5 with 5'p 24-mer dsrna
and adp-mg2+ at 2.75 Å resolution. . SNAP output
|
|
5jc9
|
ribosome |
X-ray (3.03 Å) |
Cocozaki AI, Altman RB, Huang J, Buurman ET,
Kazmirski SL, Doig P, Prince DB, Blanchard SC, Cate JH,
Ferguson AD |
(2016) "Resistance
mutations generate divergent antibiotic susceptibility
profiles against translation inhibitors."
Proc.Natl.Acad.Sci.USA, 113,
8188-8193. doi: 10.1073/pnas.1605127113.
|
Structure of the escherichia coli ribosome with the
u1052g mutation in the 16s rrna . SNAP output
|
|
5jcf
|
immune system |
X-ray (2.6 Å) |
Uchikawa E, Lethier M, Malet H, Brunel J, Gerlier D,
Cusack S |
(2016) "Structural
Analysis of dsRNA Binding to Anti-viral Pattern
Recognition Receptors LGP2 and MDA5."
Mol.Cell, 62, 586-602. doi:
10.1016/j.molcel.2016.04.021.
|
Crystal structure of chicken mda5 with 5'p 10-mer dsrna
and adp-mg2+ at 2.6 Å resolution (orthorhombic form). .
SNAP output
|
|
5jch
|
immune system |
X-ray (2.95 Å) |
Uchikawa E, Lethier M, Malet H, Brunel J, Gerlier D,
Cusack S |
(2016) "Structural
Analysis of dsRNA Binding to Anti-viral Pattern
Recognition Receptors LGP2 and MDA5."
Mol.Cell, 62, 586-602. doi:
10.1016/j.molcel.2016.04.021.
|
Crystal structure of chicken mda5 with 5'p 10-mer dsrna
and adp-mg2+ at 2.95 Å resolution (untwinned). .
SNAP output
|
|
5jcs
|
ribosome |
cryo-EM (9.5 Å) |
Barrio-Garcia C, Thoms M, Flemming D, Kater L,
Berninghausen O, Bassler J, Beckmann R, Hurt E |
(2016) "Architecture
of the Rix1-Rea1 checkpoint machinery during
pre-60S-ribosome remodeling."
Nat.Struct.Mol.Biol., 23,
37-44. doi: 10.1038/nsmb.3132.
|
cryo-EM structure of the rix1-rea1 pre-60s particle .
SNAP output
|
|
5jea
|
hydrolase-RNA |
X-ray (2.65 Å) |
Kowalinski E, Kogel A, Ebert J, Reichelt P, Stegmann
E, Habermann B, Conti E |
(2016) "Structure
of a Cytoplasmic 11-Subunit RNA Exosome Complex."
Mol.Cell, 63, 125-134. doi:
10.1016/j.molcel.2016.05.028.
|
Structure of a cytoplasmic 11-subunit RNA exosome
complex including ski7, bound to RNA . SNAP output
|
|
5jji
|
transcription-RNA |
X-ray (2.601 Å) |
Thomsen ND, Lawson MR, Witkowsky LB, Qu S, Berger
JM |
(2016) "Molecular
mechanisms of substrate-controlled ring dynamics and
substepping in a nucleic acid-dependent hexameric
motor." Proc. Natl. Acad. Sci. U.S.A.,
113, E7691-E7700. doi: 10.1073/pnas.1616745113.
|
Rho transcription termination factor bound to ru7 and 6
adp-bef3 molecules . SNAP output
|
|
5jjk
|
transcription-RNA |
X-ray (3.15 Å) |
Thomsen ND, Lawson MR, Witkowsky LB, Qu S, Berger
JM |
(2016) "Molecular
mechanisms of substrate-controlled ring dynamics and
substepping in a nucleic acid-dependent hexameric
motor." Proc. Natl. Acad. Sci. U.S.A.,
113, E7691-E7700. doi: 10.1073/pnas.1616745113.
|
Rho transcription termination factor bound to ra7 and 6
adp-bef3 molecules . SNAP output
|
|
5jjl
|
transcription-RNA |
X-ray (3.2 Å) |
Thomsen ND, Lawson MR, Witkowsky LB, Qu S, Berger
JM |
(2016) "Molecular
mechanisms of substrate-controlled ring dynamics and
substepping in a nucleic acid-dependent hexameric
motor." Proc. Natl. Acad. Sci. U.S.A.,
113, E7691-E7700. doi: 10.1073/pnas.1616745113.
|
Rho transcription termination factor bound to ru8 and 5
adp-bef3 molecules . SNAP output
|
|
5jju
|
hydrolase-RNA |
X-ray (2.312 Å) |
He Q, Wang F, Liu S, Zhu D, Cong H, Gao F, Li B, Wang
H, Lin Z, Liao J, Gu L |
(2016) "Structural
and biochemical insight into the mechanism of Rv2837c
from Mycobacterium tuberculosis as a c-di-NMP
phosphodiesterase." J.Biol.Chem.,
291, 14386-14387. doi: 10.1074/jbc.A115.699801.
|
Crystal structure of rv2837c complexed with 5'-papa and
5'-amp . SNAP output
|
|
5jpq
|
ribosome |
cryo-EM (7.3 Å) |
Kornprobst M, Turk M, Kellner N, Cheng J, Flemming D,
Kos-Braun I, Kos M, Thoms M, Berninghausen O, Beckmann R,
Hurt E |
(2016) "Architecture
of the 90S Pre-ribosome: A Structural View on the Birth
of the Eukaryotic Ribosome." Cell,
166, 380-393. doi: 10.1016/j.cell.2016.06.014.
|
cryo-EM structure of the 90s pre-ribosome . SNAP output
|
|
5jrc
|
DNA binding protein |
X-ray (1.9 Å) |
Zhang J, Liu H, Yao Q, Yu X, Chen Y, Cui R, Wu B,
Zheng L, Zuo J, Huang Z, Ma J, Gan J |
(2016) "Structural
basis for single-stranded RNA recognition and cleavage
by C3PO." Nucleic Acids Res.,
44, 9494-9504. doi: 10.1093/nar/gkw776.
|
Crystal structure of nec3po in complex with ssrna. .
SNAP output
|
|
5js1
|
hydrolase-RNA |
X-ray (2.499 Å) |
Schirle NT, Kinberger GA, Murray HF, Lima WF, Prakash
TP, MacRae IJ |
(2016) "Structural
Analysis of Human Argonaute-2 Bound to a Modified siRNA
Guide." J.Am.Chem.Soc.,
138, 8694-8697. doi: 10.1021/jacs.6b04454.
|
Human argonaute2 bound to an sirna . SNAP output
|
|
5js2
|
hydrolase-RNA |
X-ray (2.954 Å) |
Schirle NT, Kinberger GA, Murray HF, Lima WF, Prakash
TP, MacRae IJ |
(2016) "Structural
Analysis of Human Argonaute-2 Bound to a Modified siRNA
Guide." J.Am.Chem.Soc.,
138, 8694-8697. doi: 10.1021/jacs.6b04454.
|
Human argonaute-2 bound to a modified sirna . SNAP output
|
|
5jte
|
ribosome |
cryo-EM (3.6 Å) |
Arenz S, Bock LV, Graf M, Innis CA, Beckmann R,
Grubmuller H, Vaiana AC, Wilson DN |
(2016) "A
combined cryo-EM and molecular dynamics approach
reveals the mechanism of ErmBL-mediated translation
arrest." Nat Commun, 7,
12026. doi: 10.1038/ncomms12026.
|
cryo-EM structure of an ermbl-stalled ribosome in
complex with a-, p-, and e-trna . SNAP output
|
|
5ju8
|
ribosome |
cryo-EM (3.6 Å) |
Arenz S, Bock LV, Graf M, Innis CA, Beckmann R,
Grubmuller H, Vaiana AC, Wilson DN |
(2016) "A
combined cryo-EM and molecular dynamics approach
reveals the mechanism of ErmBL-mediated translation
arrest." Nat Commun, 7,
12026. doi: 10.1038/ncomms12026.
|
cryo-EM structure of an ermbl-stalled ribosome in
complex with p-, and e-trna . SNAP output
|
|
5jvg
|
ribosome |
X-ray (3.428 Å) |
Krupkin M, Wekselman I, Matzov D, Eyal Z, Diskin
Posner Y, Rozenberg H, Zimmerman E, Bashan A, Yonath
A |
(2016) "Avilamycin
and evernimicin induce structural changes in rProteins
uL16 and CTC that enhance the inhibition of A-site tRNA
binding." Proc.Natl.Acad.Sci.USA,
113, E6796-E6805. doi: 10.1073/pnas.1614297113.
|
The large ribosomal subunit from deinococcus
radiodurans in complex with avilamycin . SNAP output
|
|
5jvh
|
ribosome |
X-ray (3.58 Å) |
Krupkin M, Wekselman I, Matzov D, Eyal Z, Diskin
Posner Y, Rozenberg H, Zimmerman E, Bashan A, Yonath
A |
(2016) "Avilamycin
and evernimicin induce structural changes in rProteins
uL16 and CTC that enhance the inhibition of A-site tRNA
binding." Proc.Natl.Acad.Sci.USA,
113, E6796-E6805. doi: 10.1073/pnas.1614297113.
|
The crystal structure large ribosomal subunit (50s) of
deinococcus radiodurans in complex with evernimicin .
SNAP output
|
|
5jxs
|
transferase |
X-ray (2.8 Å) |
Herod MR, Ferrer-Orta C, Loundras EA, Ward JC,
Verdaguer N, Rowlands DJ, Stonehouse NJ |
(2016) "Both cis
and trans Activities of Foot-and-Mouth Disease Virus 3D
Polymerase Are Essential for Viral RNA
Replication." J.Virol.,
90, 6864-6883. doi: 10.1128/JVI.00469-16.
|
Mutant gc216-7aa of 3d polymerase from foot-and-mouth
disease virus . SNAP
output
|
|
5k0y
|
translation |
cryo-EM (5.8 Å) |
Simonetti A, Brito Querido J, Myasnikov AG,
Mancera-Martinez E, Renaud A, Kuhn L, Hashem Y |
(2016) "eIF3
Peripheral Subunits Rearrangement after mRNA Binding
and Start-Codon Recognition." Mol.Cell,
63, 206-217. doi: 10.1016/j.molcel.2016.05.033.
|
M48s late-stage initiation complex, purified from
rabbit reticulocytes lysates, displaying eif2 ternary
complex and eif3 i and g subunits relocated to the
intersubunit face . SNAP
output
|
|
5k36
|
hydrolase-RNA |
X-ray (3.1 Å) |
Zinder JC, Wasmuth EV, Lima CD |
(2016) "Nuclear
RNA Exosome at 3.1 angstrom Reveals Substrate
Specificities, RNA Paths, and Allosteric Inhibition of
Rrp44/Dis3." Mol.Cell,
64, 734-745. doi: 10.1016/j.molcel.2016.09.038.
|
Structure of an eleven component nuclear RNA exosome
complex bound to RNA . SNAP output
|
|
5kal
|
transferase-RNA |
X-ray (2.75 Å) |
Rajappa-Titu L, Suematsu T, Munoz-Tello P, Long M,
Demir O, Cheng KJ, Stagno JR, Luecke H, Amaro RE,
Aphasizheva I, Aphasizhev R, Thore S |
(2016) "RNA
Editing TUTase 1: structural foundation of substrate
recognition, complex interactions and drug
targeting." Nucleic Acids Res.,
44, 10862-10878. doi: 10.1093/nar/gkw917.
|
Terminal uridylyl transferase 4 from trypanosoma brucei
with bound utp and upu . SNAP output
|
|
5kcr
|
ribosome |
cryo-EM (3.6 Å) |
Arenz S, Juette MF, Graf M, Nguyen F, Huter P,
Polikanov YS, Blanchard SC, Wilson DN |
(2016) "Structures
of the orthosomycin antibiotics avilamycin and
evernimicin in complex with the bacterial 70S
ribosome." Proc.Natl.Acad.Sci.USA,
113, 7527-7532. doi: 10.1073/pnas.1604790113.
|
cryo-EM structure of the escherichia coli 70s ribosome
in complex with antibiotic avilamycin c, mrna and
p-site trna at 3.6a resolution . SNAP output
|
|
5kcs
|
ribosome |
cryo-EM (3.9 Å) |
Arenz S, Juette MF, Graf M, Nguyen F, Huter P,
Polikanov YS, Blanchard SC, Wilson DN |
(2016) "Structures
of the orthosomycin antibiotics avilamycin and
evernimicin in complex with the bacterial 70S
ribosome." Proc.Natl.Acad.Sci.USA,
113, 7527-7532. doi: 10.1073/pnas.1604790113.
|
cryo-EM structure of the escherichia coli 70s ribosome
in complex with antibiotic evernimycin, mrna, tetm and
p-site trna at 3.9a resolution . SNAP output
|
|
5ki6
|
hydrolase-RNA |
X-ray (2.153 Å) |
Suter SR, Sheu-Gruttadauria J, Schirle NT, Valenzuela
R, Ball-Jones AA, Onizuka K, MacRae IJ, Beal PA |
(2016) "Structure-Guided
Control of siRNA Off-Target Effects."
J.Am.Chem.Soc., 138,
8667-8669. doi: 10.1021/jacs.6b06137.
|
Human argonaute-2 bound to a guide RNA with a
nucleobase modification at position 1 . SNAP output
|
|
5kl1
|
RNA binding protein-RNA |
X-ray (3.701 Å) |
Weidmann CA, Qiu C, Arvola RM, Lou TF, Killingsworth
J, Campbell ZT, Tanaka Hall TM, Goldstrohm AC |
(2016) "Drosophila
Nanos acts as a molecular clamp that modulates the
RNA-binding and repression activities of Pumilio."
Elife, 5. doi: 10.7554/eLife.17096.
|
Crystal structure of the pumilio-nos-hunchback RNA
complex . SNAP
output
|
|
5kl8
|
RNA-binding protein-RNA |
X-ray (4.0 Å) |
Weidmann CA, Qiu C, Arvola RM, Lou TF, Killingsworth
J, Campbell ZT, Tanaka Hall TM, Goldstrohm AC |
(2016) "Drosophila
Nanos acts as a molecular clamp that modulates the
RNA-binding and repression activities of Pumilio."
Elife, 5. doi: 10.7554/eLife.17096.
|
Crystal structure of the pumilio-nos-cyclinb RNA
complex . SNAP
output
|
|
5kla
|
RNA-binding protein-RNA |
X-ray (1.14 Å) |
Weidmann CA, Qiu C, Arvola RM, Lou TF, Killingsworth
J, Campbell ZT, Tanaka Hall TM, Goldstrohm AC |
(2016) "Drosophila
Nanos acts as a molecular clamp that modulates the
RNA-binding and repression activities of Pumilio."
Elife, 5. doi: 10.7554/eLife.17096.
|
Crystal structure of the drosophila pumilio RNA-binding
domain in complex with hunchback RNA . SNAP output
|
|
5kps
|
ribosome |
cryo-EM (3.9 Å) |
Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF,
Grigorieff N, Korostelev AA |
(2016) "Ribosome•RelA
structures reveal the mechanism of stringent response
activation." Elife, 5.
doi: 10.7554/eLife.17029.
|
Structure of rela bound to ribosome in absence of a-r
trna (structure i) . SNAP output
|
|
5kpv
|
ribosome |
cryo-EM (4.1 Å) |
Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF,
Grigorieff N, Korostelev AA |
(2016) "Ribosome•RelA
structures reveal the mechanism of stringent response
activation." Elife, 5.
doi: 10.7554/eLife.17029.
|
Structure of rela bound to ribosome in presence of a-r
trna (structure ii) . SNAP output
|
|
5kpw
|
ribosome |
cryo-EM (3.9 Å) |
Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF,
Grigorieff N, Korostelev AA |
(2016) "Ribosome•RelA
structures reveal the mechanism of stringent response
activation." Elife, 5.
doi: 10.7554/eLife.17029.
|
Structure of rela bound to ribosome in presence of a-r
trna (structure iii) . SNAP output
|
|
5kpx
|
ribosome |
cryo-EM (3.9 Å) |
Loveland AB, Bah E, Madireddy R, Zhang Y, Brilot AF,
Grigorieff N, Korostelev AA |
(2016) "Ribosome•RelA
structures reveal the mechanism of stringent response
activation." Elife, 5.
doi: 10.7554/eLife.17029.
|
Structure of rela bound to ribosome in presence of a-r
trna (structure iv) . SNAP output
|
|
5l1z
|
transcription-RNA |
X-ray (5.9 Å) |
Schulze-Gahmen U, Echeverria I, Stjepanovic G, Bai Y,
Lu H, Schneidman-Duhovny D, Doudna JA, Zhou Q, Sali A,
Hurley JH |
(2016) "Insights
into HIV-1 proviral transcription from integrative
structure and dynamics of the Tat:AFF4:P-TEFb:TAR
complex." Elife, 5. doi:
10.7554/eLife.15910.
|
Tar complex with hiv-1 tat-aff4-p-tefb . SNAP output
|
|
5l2l
|
RNA binding protein |
X-ray (1.55 Å) |
Aibara S, Gordon JM, Riesterer AS, McLaughlin SH,
Stewart M |
(2017) "Structural
basis for the dimerization of Nab2 generated by RNA
binding provides insight into its contribution to both
poly(A) tail length determination and transcript
compaction in Saccharomyces cerevisiae."
Nucleic Acids Res., 45,
1529-1538. doi: 10.1093/nar/gkw1224.
|
Nab2 zn fingers 5-7 bound to a11g RNA . SNAP output
|
|
5l3p
|
ribosome |
cryo-EM (3.7 Å) |
Arenz S, Abdelshahid M, Sohmen D, Payoe R, Starosta
AL, Berninghausen O, Hauryliuk V, Beckmann R, Wilson
DN |
(2016) "The
stringent factor RelA adopts an open conformation on
the ribosome to stimulate ppGpp synthesis."
Nucleic Acids Res., 44,
6471-6481. doi: 10.1093/nar/gkw470.
|
cryo-EM structure of stringent response factor rela
bound to ermcl-stalled ribosome complex . SNAP output
|
|
5li0
|
ribosome |
cryo-EM (3.8 Å) |
Khusainov I, Vicens Q, Bochler A, Grosse F, Myasnikov
A, Menetret JF, Chicher J, Marzi S, Romby P, Yusupova G,
Yusupov M, Hashem Y |
(2016) "Structure
of the 70S ribosome from human pathogen Staphylococcus
aureus." Nucleic Acids Res.,
44, 10491-10504. doi: 10.1093/nar/gkw933.
|
70s ribosome from staphylococcus aureus . SNAP output
|
|
5lj3
|
splicing |
cryo-EM (3.8 Å) |
Galej WP, Wilkinson ME, Fica SM, Oubridge C, Newman
AJ, Nagai K |
(2016) "Cryo-EM
structure of the spliceosome immediately after
branching." Nature, 537,
197-201. doi: 10.1038/nature19316.
|
Structure of the core of the yeast spliceosome
immediately after branching . SNAP output
|
|
5lj5
|
splicing |
cryo-EM (10.0 Å) |
Galej WP, Wilkinson ME, Fica SM, Oubridge C, Newman
AJ, Nagai K |
(2016) "Cryo-EM
structure of the spliceosome immediately after
branching." Nature, 537,
197-201. doi: 10.1038/nature19316.
|
Overall structure of the yeast spliceosome immediately
after branching. . SNAP
output
|
|
5ll6
|
ribosome |
cryo-EM (3.9 Å) |
Heuer A, Gerovac M, Schmidt C, Trowitzsch S, Preis A,
Kotter P, Berninghausen O, Becker T, Beckmann R, Tampe
R |
(2017) "Structure
of the 40S-ABCE1 post-splitting complex in ribosome
recycling and translation initiation." Nat.
Struct. Mol. Biol., 24, 453-460.
doi: 10.1038/nsmb.3396.
|
Structure of the 40s abce1 post-splitting complex in
ribosome recycling and translation initiation .
SNAP output
|
|
5lm7
|
transcription |
X-ray (3.35 Å) |
Said N, Krupp F, Anedchenko E, Santos KF, Dybkov O,
Huang YH, Lee CT, Loll B, Behrmann E, Burger J, Mielke T,
Loerke J, Urlaub H, Spahn CMT, Weber G, Wahl MC |
(2017) "Structural
basis for lambda N-dependent processive transcription
antitermination." Nat Microbiol,
2, 17062. doi: 10.1038/nmicrobiol.2017.62.
|
Crystal structure of the lambda n-nus factor complex .
SNAP output
|
|
5lmn
|
ribosome |
cryo-EM (3.55 Å) |
Hussain T, Llacer JL, Wimberly BT, Kieft JS,
Ramakrishnan V |
(2016) "Large-Scale
Movements of IF3 and tRNA during Bacterial Translation
Initiation." Cell, 167,
133-144.e13. doi: 10.1016/j.cell.2016.08.074.
|
Structure of bacterial 30s-if1-if3-mrna translation
pre-initiation complex (state-1a) . SNAP output
|
|
5lmo
|
ribosome |
cryo-EM (4.3 Å) |
Hussain T, Llacer JL, Wimberly BT, Kieft JS,
Ramakrishnan V |
(2016) "Large-Scale
Movements of IF3 and tRNA during Bacterial Translation
Initiation." Cell, 167,
133-144.e13. doi: 10.1016/j.cell.2016.08.074.
|
Structure of bacterial 30s-if1-if3-mrna translation
pre-initiation complex (state-1b) . SNAP output
|
|
5lmp
|
ribosome |
cryo-EM (5.35 Å) |
Hussain T, Llacer JL, Wimberly BT, Kieft JS,
Ramakrishnan V |
(2016) "Large-Scale
Movements of IF3 and tRNA during Bacterial Translation
Initiation." Cell, 167,
133-144.e13. doi: 10.1016/j.cell.2016.08.074.
|
Structure of bacterial 30s-if1-if3-mrna translation
pre-initiation complex (state-1c) . SNAP output
|
|
5lmq
|
ribosome |
cryo-EM (4.2 Å) |
Hussain T, Llacer JL, Wimberly BT, Kieft JS,
Ramakrishnan V |
(2016) "Large-Scale
Movements of IF3 and tRNA during Bacterial Translation
Initiation." Cell, 167,
133-144.e13. doi: 10.1016/j.cell.2016.08.074.
|
Structure of bacterial 30s-if1-if3-mrna-trna
translation pre-initiation complex, open form
(state-2a) . SNAP
output
|
|
5lmr
|
ribosome |
cryo-EM (4.45 Å) |
Hussain T, Llacer JL, Wimberly BT, Kieft JS,
Ramakrishnan V |
(2016) "Large-Scale
Movements of IF3 and tRNA during Bacterial Translation
Initiation." Cell, 167,
133-144.e13. doi: 10.1016/j.cell.2016.08.074.
|
Structure of bacterial 30s-if1-if3-mrna-trna
translation pre-initiation complex(state-2b) . SNAP output
|
|
5lms
|
ribosome |
cryo-EM (5.1 Å) |
Hussain T, Llacer JL, Wimberly BT, Kieft JS,
Ramakrishnan V |
(2016) "Large-Scale
Movements of IF3 and tRNA during Bacterial Translation
Initiation." Cell, 167,
133-144.e13. doi: 10.1016/j.cell.2016.08.074.
|
Structure of bacterial 30s-if1-if3-mrna-trna
translation pre-initiation complex(state-2c) . SNAP output
|
|
5lmt
|
ribosome |
cryo-EM (4.15 Å) |
Hussain T, Llacer JL, Wimberly BT, Kieft JS,
Ramakrishnan V |
(2016) "Large-Scale
Movements of IF3 and tRNA during Bacterial Translation
Initiation." Cell, 167,
133-144.e13. doi: 10.1016/j.cell.2016.08.074.
|
Structure of bacterial 30s-if1-if3-mrna-trna
translation pre-initiation complex(state-3) . SNAP output
|
|
5lmu
|
ribosome |
cryo-EM (4.0 Å) |
Hussain T, Llacer JL, Wimberly BT, Kieft JS,
Ramakrishnan V |
(2016) "Large-Scale
Movements of IF3 and tRNA during Bacterial Translation
Initiation." Cell, 167,
133-144.e13. doi: 10.1016/j.cell.2016.08.074.
|
Structure of bacterial 30s-if3-mrna-trna translation
pre-initiation complex, closed form (state-4) .
SNAP output
|
|
5lmv
|
ribosome |
cryo-EM (4.9 Å) |
Hussain T, Llacer JL, Wimberly BT, Kieft JS,
Ramakrishnan V |
(2016) "Large-Scale
Movements of IF3 and tRNA during Bacterial Translation
Initiation." Cell, 167,
133-144.e13. doi: 10.1016/j.cell.2016.08.074.
|
Structure of bacterial 30s-if1-if2-if3-mrna-trna
translation pre-initiation complex(state-iii) .
SNAP output
|
|
5lta
|
protein-RNA |
X-ray (2.621 Å) |
Tauchert MJ, Fourmann JB, Luhrmann R, Ficner R |
(2017) "Structural
insights into the mechanism of the DEAH-box RNA
helicase Prp43." Elife,
6. doi: 10.7554/eLife.21510.
|
Crystal structure of the prp43-adp-bef3-u7-RNA complex
. SNAP output
|
|
5lyb
|
ribosome |
X-ray (3.25 Å) |
Melnikov S, Mailliot J, Rigger L, Neuner S, Shin BS,
Yusupova G, Dever TE, Micura R, Yusupov M |
(2016) "Molecular
insights into protein synthesis with proline
residues." EMBO Rep., 17,
1776-1784. doi: 10.15252/embr.201642943.
|
Crystal structure of the s.cerevisiae 80s ribosome in
complex with the a-site bound aminoacyl-trna analog
accpmn . SNAP output
|
|
5lza
|
ribosome |
cryo-EM (3.6 Å) |
Fischer N, Neumann P, Bock LV, Maracci C, Wang Z,
Paleskava A, Konevega AL, Schroder GF, Grubmuller H,
Ficner R, Rodnina MV, Stark H |
(2016) "The
pathway to GTPase activation of elongation factor SelB
on the ribosome." Nature,
540, 80-85. doi: 10.1038/nature20560.
|
Structure of the 70s ribosome with secis-mrna and
p-site trna (initial complex, ic) . SNAP output
|
|
5lzb
|
ribosome |
cryo-EM (5.3 Å) |
Fischer N, Neumann P, Bock LV, Maracci C, Wang Z,
Paleskava A, Konevega AL, Schroder GF, Grubmuller H,
Ficner R, Rodnina MV, Stark H |
(2016) "The
pathway to GTPase activation of elongation factor SelB
on the ribosome." Nature,
540, 80-85. doi: 10.1038/nature20560.
|
Structure of selb-sec-trnasec bound to the 70s ribosome
in the initial binding state (ib) . SNAP output
|
|
5lzc
|
ribosome |
cryo-EM (4.8 Å) |
Fischer N, Neumann P, Bock LV, Maracci C, Wang Z,
Paleskava A, Konevega AL, Schroder GF, Grubmuller H,
Ficner R, Rodnina MV, Stark H |
(2016) "The
pathway to GTPase activation of elongation factor SelB
on the ribosome." Nature,
540, 80-85. doi: 10.1038/nature20560.
|
Structure of selb-sec-trnasec bound to the 70s ribosome
in the codon reading state (cr) . SNAP output
|
|
5lzd
|
ribosome |
cryo-EM (3.4 Å) |
Fischer N, Neumann P, Bock LV, Maracci C, Wang Z,
Paleskava A, Konevega AL, Schroder GF, Grubmuller H,
Ficner R, Rodnina MV, Stark H |
(2016) "The
pathway to GTPase activation of elongation factor SelB
on the ribosome." Nature,
540, 80-85. doi: 10.1038/nature20560.
|
Structure of selb-sec-trnasec bound to the 70s ribosome
in the gtpase activated state (ga) . SNAP output
|
|
5lze
|
ribosome |
cryo-EM (3.5 Å) |
Fischer N, Neumann P, Bock LV, Maracci C, Wang Z,
Paleskava A, Konevega AL, Schroder GF, Grubmuller H,
Ficner R, Rodnina MV, Stark H |
(2016) "The
pathway to GTPase activation of elongation factor SelB
on the ribosome." Nature,
540, 80-85. doi: 10.1038/nature20560.
|
Structure of the 70s ribosome with sec-trnasec in the
classical pre-translocation state (c) . SNAP output
|
|
5lzf
|
ribosome |
cryo-EM (4.6 Å) |
Fischer N, Neumann P, Bock LV, Maracci C, Wang Z,
Paleskava A, Konevega AL, Schroder GF, Grubmuller H,
Ficner R, Rodnina MV, Stark H |
(2016) "The
pathway to GTPase activation of elongation factor SelB
on the ribosome." Nature,
540, 80-85. doi: 10.1038/nature20560.
|
Structure of the 70s ribosome with fmetsec-trnasec in
the hybrid pre-translocation state (h) . SNAP output
|
|
5lzs
|
ribosome |
cryo-EM (3.31 Å) |
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V,
Hegde RS |
(2016) "Decoding
Mammalian Ribosome-mRNA States by Translational GTPase
Complexes." Cell, 167,
1229-1240.e15. doi: 10.1016/j.cell.2016.10.046.
|
Structure of the mammalian ribosomal elongation complex
with aminoacyl-trna, eef1a, and didemnin b . SNAP output
|
|
5lzt
|
ribosome |
cryo-EM (3.65 Å) |
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V,
Hegde RS |
(2016) "Decoding
Mammalian Ribosome-mRNA States by Translational GTPase
Complexes." Cell, 167,
1229-1240.e15. doi: 10.1016/j.cell.2016.10.046.
|
Structure of the mammalian ribosomal termination
complex with erf1 and erf3. . SNAP output
|
|
5lzu
|
ribosome |
cryo-EM (3.75 Å) |
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V,
Hegde RS |
(2016) "Decoding
Mammalian Ribosome-mRNA States by Translational GTPase
Complexes." Cell, 167,
1229-1240.e15. doi: 10.1016/j.cell.2016.10.046.
|
Structure of the mammalian ribosomal termination
complex with accommodated erf1 . SNAP output
|
|
5lzv
|
ribosome |
cryo-EM (3.35 Å) |
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V,
Hegde RS |
(2016) "Decoding
Mammalian Ribosome-mRNA States by Translational GTPase
Complexes." Cell, 167,
1229-1240.e15. doi: 10.1016/j.cell.2016.10.046.
|
Structure of the mammalian ribosomal termination
complex with accommodated erf1(aaq) and abce1. .
SNAP output
|
|
5lzw
|
ribosome |
cryo-EM (3.53 Å) |
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V,
Hegde RS |
(2016) "Decoding
Mammalian Ribosome-mRNA States by Translational GTPase
Complexes." Cell, 167,
1229-1240.e15. doi: 10.1016/j.cell.2016.10.046.
|
Structure of the mammalian rescue complex with pelota
and hbs1l assembled on a truncated mrna. . SNAP output
|
|
5lzx
|
ribosome |
cryo-EM (3.67 Å) |
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V,
Hegde RS |
(2016) "Decoding
Mammalian Ribosome-mRNA States by Translational GTPase
Complexes." Cell, 167,
1229-1240.e15. doi: 10.1016/j.cell.2016.10.046.
|
Structure of the mammalian rescue complex with pelota
and hbs1l assembled on a uga stop codon. . SNAP output
|
|
5lzy
|
ribosome |
cryo-EM (3.99 Å) |
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V,
Hegde RS |
(2016) "Decoding
Mammalian Ribosome-mRNA States by Translational GTPase
Complexes." Cell, 167,
1229-1240.e15. doi: 10.1016/j.cell.2016.10.046.
|
Structure of the mammalian rescue complex with pelota
and hbs1l assembled on a polyadenylated mrna. .
SNAP output
|
|
5lzz
|
ribosome |
cryo-EM (3.47 Å) |
Shao S, Murray J, Brown A, Taunton J, Ramakrishnan V,
Hegde RS |
(2016) "Decoding
Mammalian Ribosome-mRNA States by Translational GTPase
Complexes." Cell, 167,
1229-1240.e15. doi: 10.1016/j.cell.2016.10.046.
|
Structure of the mammalian rescue complex with pelota
and hbs1l (combined) . SNAP output
|
|
5m0i
|
transport protein |
X-ray (2.41 Å) |
Edelmann FT, Schlundt A, Heym RG, Jenner A,
Niedner-Boblenz A, Syed MI, Paillart JC, Stehle R,
Janowski R, Sattler M, Jansen RP, Niessing D |
(2017) "Molecular
architecture and dynamics of ASH1 mRNA recognition by
its mRNA-transport complex." Nat. Struct. Mol.
Biol., 24, 152-161. doi: 10.1038/nsmb.3351.
|
Crystal structure of the nuclear complex with she2p and
the ash1 mrna e3-localization element . SNAP output
|
|
5m0j
|
RNA binding protein |
X-ray (2.8 Å) |
Edelmann FT, Schlundt A, Heym RG, Jenner A,
Niedner-Boblenz A, Syed MI, Paillart JC, Stehle R,
Janowski R, Sattler M, Jansen RP, Niessing D |
(2017) "Molecular
architecture and dynamics of ASH1 mRNA recognition by
its mRNA-transport complex." Nat. Struct. Mol.
Biol., 24, 152-161. doi: 10.1038/nsmb.3351.
|
Crystal structure of the cytoplasmic complex with
she2p, she3p, and the ash1 mrna e3-localization element
. SNAP output
|
|
5m1j
|
ribosome |
cryo-EM (3.3 Å) |
Hilal T, Yamamoto H, Loerke J, Burger J, Mielke T,
Spahn CM |
(2016) "Structural
insights into ribosomal rescue by Dom34 and Hbs1 at
near-atomic resolution." Nat Commun,
7, 13521. doi: 10.1038/ncomms13521.
|
Nonstop ribosomal complex bound with dom34 and hbs1 .
SNAP output
|
|
5m3h
|
transferase |
X-ray (2.5 Å) |
Lukarska M, Fournier G, Pflug A, Resa-Infante P,
Reich S, Naffakh N, Cusack S |
(2017) "Structural
basis of an essential interaction between influenza
polymerase and Pol II CTD." Nature,
541, 117-121. doi: 10.1038/nature20594.
|
Bat influenza a-h17n10 polymerase bound to four heptad
repeats of serine 5 phosphorylated pol ii ctd .
SNAP output
|
|
5m3j
|
viral protein |
X-ray (3.5 Å) |
Lukarska M, Fournier G, Pflug A, Resa-Infante P,
Reich S, Naffakh N, Cusack S |
(2017) "Structural
basis of an essential interaction between influenza
polymerase and Pol II CTD." Nature,
541, 117-121. doi: 10.1038/nature20594.
|
Influenza b polymerase bound to four heptad repeats of
serine 5 phosphorylated pol ii ctd . SNAP output
|
|
5m73
|
RNA binding protein |
X-ray (3.4 Å) |
Becker MM, Lapouge K, Segnitz B, Wild K, Sinning
I |
(2017) "Structures
of human SRP72 complexes provide insights into SRP RNA
remodeling and ribosome interaction." Nucleic
Acids Res., 45, 470-481. doi:
10.1093/nar/gkw1124.
|
Structure of the human srp s domain with srp72
RNA-binding domain . SNAP output
|
|
5m8i
|
RNA binding protein |
NMR |
Diarra Dit Konte N, Krepl M, Damberger FF, Ripin N,
Duss O, Sponer J, Allain FH |
(2017) "Aromatic
side-chain conformational switch on the surface of the
RNA Recognition Motif enables RNA discrimination."
Nat Commun, 8, 654. doi:
10.1038/s41467-017-00631-3.
|
Solution structure of cug-bp2 rrm3 in complex with
5'-uuuaa-3' RNA . SNAP
output
|
|
5mc6
|
ribosome |
cryo-EM (3.8 Å) |
Schmidt C, Kowalinski E, Shanmuganathan V,
Defenouillere Q, Braunger K, Heuer A, Pech M, Namane A,
Berninghausen O, Fromont-Racine M, Jacquier A, Conti E,
Becker T, Beckmann R |
(2016) "The
cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase
complex." Science, 354,
1431-1433. doi: 10.1126/science.aaf7520.
|
cryo-EM structure of a native ribosome-ski2-ski3-ski8
complex from s. cerevisiae . SNAP output
|
|
5mdv
|
ribosome |
cryo-EM (2.97 Å) |
James NR, Brown A, Gordiyenko Y, Ramakrishnan V |
(2016) "Translational
termination without a stop codon."
Science, 354, 1437-1440. doi:
10.1126/science.aai9127.
|
Structure of arfa and rf2 bound to the 70s ribosome
(accommodated state) . SNAP output
|
|
5mdw
|
ribosome |
cryo-EM (3.06 Å) |
James NR, Brown A, Gordiyenko Y, Ramakrishnan V |
(2016) "Translational
termination without a stop codon."
Science, 354, 1437-1440. doi:
10.1126/science.aai9127.
|
Structure of arfa(a18t) and rf2 bound to the 70s
ribosome (pre-accommodated state) . SNAP output
|
|
5mdy
|
ribosome |
cryo-EM (3.35 Å) |
James NR, Brown A, Gordiyenko Y, Ramakrishnan V |
(2016) "Translational
termination without a stop codon."
Science, 354, 1437-1440. doi:
10.1126/science.aai9127.
|
Structure of arfa and ttrf2 bound to the 70s ribosome
(pre-accommodated state) . SNAP output
|
|
5mdz
|
ribosome |
cryo-EM (3.1 Å) |
James NR, Brown A, Gordiyenko Y, Ramakrishnan V |
(2016) "Translational
termination without a stop codon."
Science, 354, 1437-1440. doi:
10.1126/science.aai9127.
|
Structure of the 70s ribosome (empty a site) . SNAP output
|
|
5me0
|
ribosome |
cryo-EM (13.5 Å) |
Lopez-Alonso JP, Fabbretti A, Kaminishi T, Iturrioz
I, Brandi L, Gil-Carton D, Gualerzi CO, Fucini P, Connell
SR |
(2017) "Structure
of a 30S pre-initiation complex stalled by GE81112
reveals structural parallels in bacterial and
eukaryotic protein synthesis initiation pathways."
Nucleic Acids Res., 45,
2179-2187. doi: 10.1093/nar/gkw1251.
|
Structure of the 30s pre-initiation complex 1 (30s
ic-1) stalled by ge81112 . SNAP output
|
|
5me1
|
ribosome |
cryo-EM (13.5 Å) |
Lopez-Alonso JP, Fabbretti A, Kaminishi T, Iturrioz
I, Brandi L, Gil-Carton D, Gualerzi CO, Fucini P, Connell
SR |
(2017) "Structure
of a 30S pre-initiation complex stalled by GE81112
reveals structural parallels in bacterial and
eukaryotic protein synthesis initiation pathways."
Nucleic Acids Res., 45,
2179-2187. doi: 10.1093/nar/gkw1251.
|
Structure of the 30s pre-initiation complex 2 (30s
ic-2) stalled by ge81112 . SNAP output
|
|
5mei
|
ribosome |
X-ray (3.5 Å) |
McClary B, Zinshteyn B, Meyer M, Jouanneau M,
Pellegrino S, Yusupova G, Schuller A, Reyes JCP, Lu J,
Guo Z, Ayinde S, Luo C, Dang Y, Romo D, Yusupov M, Green
R, Liu JO |
(2017) "Inhibition
of Eukaryotic Translation by the Antitumor Natural
Product Agelastatin A." Cell Chem Biol,
24, 605-613.e5. doi: 10.1016/j.chembiol.2017.04.006.
|
Crystal structure of agelastatin a bound to the 80s
ribosome . SNAP
output
|
|
5mfx
|
hydrolase |
X-ray (1.598 Å) |
Jenkins HT, Ge M, Chechik M, Greive SJ, Antson
AA |
"How Zika virus NS3 helicase grips the first
nucleotide of the leading RNA strand." |
Zika ns3 helicase:RNA complex . SNAP output
|
|
5mgp
|
ribosome |
cryo-EM (3.1 Å) |
Huter P, Muller C, Beckert B, Arenz S, Berninghausen
O, Beckmann R, Wilson DN |
(2017) "Structural
basis for ArfA-RF2-mediated translation termination on
mRNAs lacking stop codons." Nature,
541, 546-549. doi: 10.1038/nature20821.
|
Structural basis for arfa-rf2 mediated translation
termination on stop-codon lacking mrnas . SNAP output
|
|
5mjv
|
virus |
X-ray (3.09 Å) |
Shakeel S, Dykeman EC, White SJ, Ora A, Cockburn JJ,
Butcher SJ, Stockley PG, Twarock R |
(2017) "Genomic
RNA folding mediates assembly of human
parechovirus." Nat Commun,
8, 5. doi: 10.1038/s41467-016-0011-z.
|
Rebuild and re-refined model for human parechovirus 1 .
SNAP output
|
|
5mlc
|
ribosome |
cryo-EM (3.6 Å) |
Graf M, Arenz S, Huter P, Donhofer A, Novacek J,
Wilson DN |
(2017) "Cryo-EM
structure of the spinach chloroplast ribosome reveals
the location of plastid-specific ribosomal proteins and
extensions." Nucleic Acids Res.,
45, 2887-2896. doi: 10.1093/nar/gkw1272.
|
cryo-EM structure of the spinach chloroplast ribosome
reveals the location of plastid-specific ribosomal
proteins and extensions . SNAP output
|
|
5mmi
|
ribosome |
cryo-EM (3.2 Å) |
Bieri P, Leibundgut M, Saurer M, Boehringer D, Ban
N |
(2017) "The
complete structure of the chloroplast 70S ribosome in
complex with translation factor pY." EMBO
J., 36, 475-486. doi: 10.15252/embj.201695959.
|
Structure of the large subunit of the chloroplast
ribosome . SNAP
output
|
|
5mmj
|
ribosome |
cryo-EM (3.6 Å) |
Bieri P, Leibundgut M, Saurer M, Boehringer D, Ban
N |
(2017) "The
complete structure of the chloroplast 70S ribosome in
complex with translation factor pY." EMBO
J., 36, 475-486. doi: 10.15252/embj.201695959.
|
Structure of the small subunit of the chloroplast
ribosome . SNAP
output
|
|
5mmm
|
ribosome |
cryo-EM (3.4 Å) |
Bieri P, Leibundgut M, Saurer M, Boehringer D, Ban
N |
(2017) "The
complete structure of the chloroplast 70S ribosome in
complex with translation factor pY." EMBO
J., 36, 475-486. doi: 10.15252/embj.201695959.
|
Structure of the 70s chloroplast ribosome . SNAP output
|
|
5mpg
|
splicing |
NMR |
Beusch I, Barraud P, Moursy A, Clery A, Allain
FH |
(2017) "Tandem
hnRNP A1 RNA recognition motifs act in concert to
repress the splicing of survival motor neuron exon
7." Elife, 6. doi:
10.7554/eLife.25736.
|
Solution NMR structure of hnrnp a1 rrm1 in complex with
5'-uuagguc-3' RNA . SNAP
output
|
|
5mpl
|
splicing |
NMR |
Beusch I, Barraud P, Moursy A, Clery A, Allain
FH |
(2017) "Tandem
hnRNP A1 RNA recognition motifs act in concert to
repress the splicing of survival motor neuron exon
7." Elife, 6. doi:
10.7554/eLife.25736.
|
Hnrnp a1 rrm2 in complex with 5'-ucaguu-3' RNA .
SNAP output
|
|
5mps
|
splicing |
cryo-EM (3.85 Å) |
Fica SM, Oubridge C, Galej WP, Wilkinson ME, Bai XC,
Newman AJ, Nagai K |
(2017) "Structure
of a spliceosome remodelled for exon ligation."
Nature, 542, 377-380. doi:
10.1038/nature21078.
|
Structure of a spliceosome remodeled for exon ligation
. SNAP output
|
|
5mq0
|
splicing |
cryo-EM (4.17 Å) |
Fica SM, Oubridge C, Galej WP, Wilkinson ME, Bai XC,
Newman AJ, Nagai K |
(2017) "Structure
of a spliceosome remodelled for exon ligation."
Nature, 542, 377-380. doi:
10.1038/nature21078.
|
Structure of a spliceosome remodeled for exon ligation
. SNAP output
|
|
5mqf
|
splicing |
cryo-EM (5.9 Å) |
Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL,
Hartmuth K, Urlaub H, Kastner B, Stark H, Lu Hrmann
R |
(2017) "Cryo-EM
structure of a human spliceosome activated for step 2
of splicing." Nature,
542, 318-323. doi: 10.1038/nature21079.
|
cryo-EM structure of a human spliceosome activated for
step 2 of splicing (c* complex) . SNAP output
|
|
5mrc
|
ribosome |
cryo-EM (3.25 Å) |
Desai N, Brown A, Amunts A, Ramakrishnan V |
(2017) "The
structure of the yeast mitochondrial ribosome."
Science, 355, 528-531. doi:
10.1126/science.aal2415.
|
Structure of the yeast mitochondrial ribosome - class a
. SNAP output
|
|
5mre
|
ribosome |
cryo-EM (3.75 Å) |
Desai N, Brown A, Amunts A, Ramakrishnan V |
(2017) "The
structure of the yeast mitochondrial ribosome."
Science, 355, 528-531. doi:
10.1126/science.aal2415.
|
Structure of the yeast mitochondrial ribosome - class b
. SNAP output
|
|
5mrf
|
ribosome |
cryo-EM (4.97 Å) |
Desai N, Brown A, Amunts A, Ramakrishnan V |
(2017) "The
structure of the yeast mitochondrial ribosome."
Science, 355, 528-531. doi:
10.1126/science.aal2415.
|
Structure of the yeast mitochondrial ribosome - class c
. SNAP output
|
|
5msf
|
virus-RNA |
X-ray (2.8 Å) |
Rowsell S, Stonehouse NJ, Convery MA, Adams CJ,
Ellington AD, Hirao I, Peabody DS, Stockley PG, Phillips
SE |
(1998) "Crystal
structures of a series of RNA aptamers complexed to the
same protein target." Nat.Struct.Biol.,
5, 970-975. doi: 10.1038/2946.
|
Ms2 protein capsid-RNA complex . SNAP output
|
|
5msg
|
viral protein |
X-ray (3.8 Å) |
Reich S, Guilligay D, Cusack S |
(2017) "An in
vitro fluorescence based study of initiation of RNA
synthesis by influenza B polymerase." Nucleic
Acids Res., 45, 3353-3368. doi:
10.1093/nar/gkx043.
|
Influenza b polymerase bound to vrna promoter and
capped RNA primer . SNAP
output
|
|
5my1
|
ribosome |
cryo-EM (7.6 Å) |
Kohler R, Mooney RA, Mills DJ, Landick R, Cramer
P |
(2017) "Architecture
of a transcribing-translating expressome."
Science, 356, 194-197. doi:
10.1126/science.aal3059.
|
E. coli expressome . SNAP output
|
|
5myj
|
ribosome |
cryo-EM (5.6 Å) |
Franken LE, Oostergetel GT, Pijning T, Puri P,
Arkhipova V, Boekema EJ, Poolman B, Guskov A |
(2017) "A
general mechanism of ribosome dimerization revealed by
single-particle cryo-electron microscopy." Nat
Commun, 8, 722. doi: 10.1038/s41467-017-00718-x.
|
Structure of 70s ribosome from lactococcus lactis .
SNAP output
|
|
5n8l
|
RNA binding protein |
NMR |
Masliah G, Maris C, Konig SL, Yulikov M, Aeschimann
F, Malinowska AL, Mabille J, Weiler J, Holla A, Hunziker
J, Meisner-Kober N, Schuler B, Jeschke G, Allain FH |
(2018) "Structural
basis of siRNA recognition by TRBP double-stranded RNA
binding domains." EMBO J.,
37. doi: 10.15252/embj.201797089.
|
Structure of trbp dsrbd 1 and 2 in complex with a 19 bp
sirna (complex b) . SNAP
output
|
|
5n8m
|
RNA binding protein |
NMR |
Masliah G, Maris C, Konig SL, Yulikov M, Aeschimann
F, Malinowska AL, Mabille J, Weiler J, Holla A, Hunziker
J, Meisner-Kober N, Schuler B, Jeschke G, Allain FH |
(2018) "Structural
basis of siRNA recognition by TRBP double-stranded RNA
binding domains." EMBO J.,
37. doi: 10.15252/embj.201797089.
|
Structure of trbp dsrbd 1 and 2 in complex with a 19 bp
sirna (complex a) . SNAP
output
|
|
5n94
|
hydrolase |
X-ray (2.428 Å) |
Chen WF, Rety S, Guo HL, Dai YX, Wu WQ, Liu NN,
Auguin D, Liu QW, Hou XM, Dou SX, Xi XG |
(2018) "Molecular
Mechanistic Insights into Drosophila DHX36-Mediated
G-Quadruplex Unfolding: A Structure-Based Model."
Structure, 26, 403-415.e4.
doi: 10.1016/j.str.2018.01.008.
|
Crystal structure of drosophila dhx36 helicase in
complex with polyu . SNAP output
|
|
5nco
|
ribosome |
cryo-EM (4.8 Å) |
Jomaa A, Fu YH, Boehringer D, Leibundgut M, Shan SO,
Ban N |
(2017) "Structure
of the quaternary complex between SRP, SR, and
translocon bound to the translating ribosome."
Nat Commun, 8, 15470. doi:
10.1038/ncomms15470.
|
Quaternary complex between srp, sr, and secyeg bound to
the translating ribosome . SNAP output
|
|
5nd8
|
ribosome |
cryo-EM (3.7 Å) |
Khusainov I, Vicens Q, Ayupov R, Usachev K, Myasnikov
A, Simonetti A, Validov S, Kieffer B, Yusupova G, Yusupov
M, Hashem Y |
(2017) "Structures
and dynamics of hibernating ribosomes from
Staphylococcus aureus mediated by intermolecular
interactions of HPF." EMBO J.,
36, 2073-2087. doi: 10.15252/embj.201696105.
|
Hibernating ribosome from staphylococcus aureus
(unrotated state) . SNAP
output
|
|
5nd9
|
ribosome |
cryo-EM (3.7 Å) |
Khusainov I, Vicens Q, Ayupov R, Usachev K, Myasnikov
A, Simonetti A, Validov S, Kieffer B, Yusupova G, Yusupov
M, Hashem Y |
(2017) "Structures
and dynamics of hibernating ribosomes from
Staphylococcus aureus mediated by intermolecular
interactions of HPF." EMBO J.,
36, 2073-2087. doi: 10.15252/embj.201696105.
|
Hibernating ribosome from staphylococcus aureus
(rotated state) . SNAP
output
|
|
5ndg
|
ribosome |
X-ray (3.7 Å) |
Prokhorova I, Altman RB, Djumagulov M, Shrestha JP,
Urzhumtsev A, Ferguson A, Chang CT, Yusupov M, Blanchard
SC, Yusupova G |
(2017) "Aminoglycoside
interactions and impacts on the eukaryotic
ribosome." Proc. Natl. Acad. Sci. U.S.A.,
114, E10899-E10908. doi: 10.1073/pnas.1715501114.
|
Crystal structure of geneticin (g418) bound to the
yeast 80s ribosome . SNAP output
|
|
5ndj
|
ribosome |
X-ray (3.15 Å) |
Prokhorova I, Altman RB, Djumagulov M, Shrestha JP,
Urzhumtsev A, Ferguson A, Chang CT, Yusupov M, Blanchard
SC, Yusupova G |
(2017) "Aminoglycoside
interactions and impacts on the eukaryotic
ribosome." Proc. Natl. Acad. Sci. U.S.A.,
114, E10899-E10908. doi: 10.1073/pnas.1715501114.
|
Crystal structure of aminoglycoside tc007 in complex
with 70s ribosome from thermus thermophilus, three
trnas and mrna (soaking) . SNAP output
|
|
5ndk
|
ribosome |
X-ray (2.95 Å) |
Prokhorova I, Altman RB, Djumagulov M, Shrestha JP,
Urzhumtsev A, Ferguson A, Chang CT, Yusupov M, Blanchard
SC, Yusupova G |
(2017) "Aminoglycoside
interactions and impacts on the eukaryotic
ribosome." Proc. Natl. Acad. Sci. U.S.A.,
114, E10899-E10908. doi: 10.1073/pnas.1715501114.
|
Crystal structure of aminoglycoside tc007
co-crystallized with 70s ribosome from thermus
thermophilus, three trnas and mrna . SNAP output
|
|
5ndv
|
ribosome |
X-ray (3.3 Å) |
Prokhorova I, Altman RB, Djumagulov M, Shrestha JP,
Urzhumtsev A, Ferguson A, Chang CT, Yusupov M, Blanchard
SC, Yusupova G |
(2017) "Aminoglycoside
interactions and impacts on the eukaryotic
ribosome." Proc. Natl. Acad. Sci. U.S.A.,
114, E10899-E10908. doi: 10.1073/pnas.1715501114.
|
Crystal structure of paromomycin bound to the yeast 80s
ribosome . SNAP
output
|
|
5ndw
|
ribosome |
X-ray (3.7 Å) |
Prokhorova I, Altman RB, Djumagulov M, Shrestha JP,
Urzhumtsev A, Ferguson A, Chang CT, Yusupov M, Blanchard
SC, Yusupova G |
(2017) "Aminoglycoside
interactions and impacts on the eukaryotic
ribosome." Proc. Natl. Acad. Sci. U.S.A.,
114, E10899-E10908. doi: 10.1073/pnas.1715501114.
|
Crystal structure of aminoglycoside tc007 bound to the
yeast 80s ribosome . SNAP output
|
|
5new
|
RNA |
X-ray (2.511 Å) |
Schulz EC, Seiler M, Zuliani C, Voigt F, Rybin V,
Pogenberg V, Mucke N, Wilmanns M, Gibson TJ, Barabas
O |
(2017) "Intermolecular
base stacking mediates RNA-RNA interaction in a crystal
structure of the RNA chaperone Hfq." Sci
Rep, 7, 9903. doi: 10.1038/s41598-017-10085-8.
|
RNA-RNA base stacking in the crystal structure of an
hfq6:RNA dimer . SNAP
output
|
|
5ng6
|
hydrolase |
X-ray (3.342 Å) |
Swarts DC, van der Oost J, Jinek M |
(2017) "Structural
Basis for Guide RNA Processing and Seed-Dependent DNA
Targeting by CRISPR-Cas12a." Mol. Cell,
66, 221-233.e4. doi: 10.1016/j.molcel.2017.03.016.
|
Crystal structure of fncas12a bound to a crrna .
SNAP output
|
|
5ngm
|
ribosome |
cryo-EM (2.9 Å) |
Matzov D, Aibara S, Basu A, Zimmerman E, Bashan A,
Yap MF, Amunts A, Yonath AE |
(2017) "The
cryo-EM structure of hibernating 100S ribosome dimer
from pathogenic Staphylococcus aureus." Nat
Commun, 8, 723. doi: 10.1038/s41467-017-00753-8.
|
2.9s structure of the 70s ribosome composing the s.
aureus 100s complex . SNAP output
|
|
5njt
|
translation |
cryo-EM (3.8 Å) |
Beckert B, Abdelshahid M, Schafer H, Steinchen W,
Arenz S, Berninghausen O, Beckmann R, Bange G, Turgay K,
Wilson DN |
(2017) "Structure
of the Bacillus subtilis hibernating 100S ribosome
reveals the basis for 70S dimerization." EMBO
J., 36, 2061-2072. doi: 10.15252/embj.201696189.
|
Structure of the bacillus subtilis hibernating 100s
ribosome reveals the basis for 70s dimerization. .
SNAP output
|
|
5no2
|
ribosome |
cryo-EM (5.16 Å) |
Lopez-Alonso JP, Kaminishi T, Kikuchi T, Hirata Y,
Iturrioz I, Dhimole N, Schedlbauer A, Hase Y, Goto S,
Kurita D, Muto A, Zhou S, Naoe C, Mills DJ, Gil-Carton D,
Takemoto C, Himeno H, Fucini P, Connell SR |
(2017) "RsgA
couples the maturation state of the 30S ribosomal
decoding center to activation of its GTPase
pocket." Nucleic Acids Res.,
45, 6945-6959. doi: 10.1093/nar/gkx324.
|
Rsga-gdpnp bound to the 30s ribosomal subunit (rsga
assembly intermediate) . SNAP output
|
|
5no3
|
ribosome |
cryo-EM (5.16 Å) |
Lopez-Alonso JP, Kaminishi T, Kikuchi T, Hirata Y,
Iturrioz I, Dhimole N, Schedlbauer A, Hase Y, Goto S,
Kurita D, Muto A, Zhou S, Naoe C, Mills DJ, Gil-Carton D,
Takemoto C, Himeno H, Fucini P, Connell SR |
(2017) "RsgA
couples the maturation state of the 30S ribosomal
decoding center to activation of its GTPase
pocket." Nucleic Acids Res.,
45, 6945-6959. doi: 10.1093/nar/gkx324.
|
Rsga-gdpnp bound to the 30s ribosomal subunit (rsga
assembly intermediate without us3) . SNAP output
|
|
5no4
|
ribosome |
cryo-EM (5.16 Å) |
Lopez-Alonso JP, Kaminishi T, Kikuchi T, Hirata Y,
Iturrioz I, Dhimole N, Schedlbauer A, Hase Y, Goto S,
Kurita D, Muto A, Zhou S, Naoe C, Mills DJ, Gil-Carton D,
Takemoto C, Himeno H, Fucini P, Connell SR |
(2017) "RsgA
couples the maturation state of the 30S ribosomal
decoding center to activation of its GTPase
pocket." Nucleic Acids Res.,
45, 6945-6959. doi: 10.1093/nar/gkx324.
|
Rsga-gdpnp bound to the 30s ribosomal subunit (rsga
assembly intermediate with us3) . SNAP output
|
|
5np6
|
ribosome |
cryo-EM (3.6 Å) |
Agirrezabala X, Samatova E, Klimova M, Zamora M,
Gil-Carton D, Rodnina MV, Valle M |
(2017) "Ribosome
rearrangements at the onset of translational
bypassing." Sci Adv, 3,
e1700147. doi: 10.1126/sciadv.1700147.
|
70s structure prior to bypassing . SNAP output
|
|
5npm
|
RNA |
X-ray (2.7 Å) |
Kostareva OS, Nevskaya NA, Tishchenko SV,
Gabdulkhakov AG, Garber MB, Nikonov SV |
(2018) "[Influence
of Nonconserved Regions of L1 Protuberance of Thermus
thermophilus Ribosome on the Affinity of L1 Protein to
23s rRNA]." Mol.Biol.(Moscow),
52, 106-111. doi: 10.7868/S0026898418010147.
|
Crystal structure of mutant ribosomal protein tthl1
lacking 8 n-terminal residues in complex with 80nt 23s
RNA from thermus thermophilus . SNAP output
|
|
5nrg
|
ribosome |
X-ray (3.442 Å) |
Matzov D, Eyal Z, Benhamou RI, Shalev-Benami M,
Halfon Y, Krupkin M, Zimmerman E, Rozenberg H, Bashan A,
Fridman M, Yonath A |
(2017) "Structural
insights of lincosamides targeting the ribosome of
Staphylococcus aureus." Nucleic Acids
Res., 45, 10284-10292. doi:
10.1093/nar/gkx658.
|
The crystal structure of the large ribosomal subunit of
staphylococcus aureus in complex with rb02 . SNAP output
|
|
5nrl
|
splicing |
cryo-EM (7.2 Å) |
Plaschka C, Lin PC, Nagai K |
(2017) "Structure
of a pre-catalytic spliceosome." Nature,
546, 617-621. doi: 10.1038/nature22799.
|
Structure of a pre-catalytic spliceosome . SNAP output
|
|
5ns3
|
RNA |
X-ray (2.4 Å) |
Liu Y, Lilley DMJ |
(2017) "Crystal
Structures of Cyanine Fluorophores Stacked onto the End
of Double-Stranded RNA." Biophys. J.,
113, 2336-2343. doi: 10.1016/j.bpj.2017.10.002.
|
Crystal structures of cy5 cyanine fluorophores stacked
onto the end of double-stranded RNA . SNAP output
|
|
5ns4
|
RNA binding protein |
X-ray (2.4 Å) |
Liu Y, Lilley DMJ |
(2017) "Crystal
Structures of Cyanine Fluorophores Stacked onto the End
of Double-Stranded RNA." Biophys. J.,
113, 2336-2343. doi: 10.1016/j.bpj.2017.10.002.
|
Crystal structures of cy3 cyanine fluorophores stacked
onto the end of double-stranded RNA . SNAP output
|
|
5nwy
|
ribosome |
cryo-EM (2.9 Å) |
Su T, Cheng J, Sohmen D, Hedman R, Berninghausen O,
von Heijne G, Wilson DN, Beckmann R |
(2017) "The
force-sensing peptide VemP employs extreme compaction
and secondary structure formation to induce ribosomal
stalling." Elife, 6. doi:
10.7554/eLife.25642.
|
2.9 a cryo-EM structure of vemp-stalled
ribosome-nascent chain complex . SNAP output
|
|
5o1y
|
transcription |
X-ray (2.45 Å) |
Franco-Echevarria E, Gonzalez-Polo N, Zorrilla S,
Martinez-Lumbreras S, Santiveri CM, Campos-Olivas R,
Sanchez M, Calvo O, Gonzalez B, Perez-Canadillas JM |
(2017) "The
structure of transcription termination factor Nrd1
reveals an original mode for GUAA recognition."
Nucleic Acids Res., 45,
10293-10305. doi: 10.1093/nar/gkx685.
|
Structure of nrd1 RNA binding domain in complex with
RNA (guaa) . SNAP
output
|
|
5o1z
|
transcription |
X-ray (3.4 Å) |
Franco-Echevarria E, Gonzalez-Polo N, Zorrilla S,
Martinez-Lumbreras S, Santiveri CM, Campos-Olivas R,
Sanchez M, Calvo O, Gonzalez B, Perez-Canadillas JM |
(2017) "The
structure of transcription termination factor Nrd1
reveals an original mode for GUAA recognition."
Nucleic Acids Res., 45,
10293-10305. doi: 10.1093/nar/gkx685.
|
Structure of nrd1 RNA binding domain in complex with
RNA (cguaaa) . SNAP
output
|
|
5o2r
|
ribosome |
cryo-EM (3.4 Å) |
Florin T, Maracci C, Graf M, Karki P, Klepacki D,
Berninghausen O, Beckmann R, Vazquez-Laslop N, Wilson DN,
Rodnina MV, Mankin AS |
(2017) "An
antimicrobial peptide that inhibits translation by
trapping release factors on the ribosome." Nat.
Struct. Mol. Biol., 24, 752-757.
doi: 10.1038/nsmb.3439.
|
cryo-EM structure of the proline-rich antimicrobial
peptide api137 bound to the terminating ribosome .
SNAP output
|
|
5o3j
|
RNA binding protein |
X-ray (2.97 Å) |
Sonntag M, Jagtap PKA, Simon B, Appavou MS, Geerlof
A, Stehle R, Gabel F, Hennig J, Sattler M |
(2017) "Segmental,
Domain-Selective Perdeuteration and Small-Angle Neutron
Scattering for Structural Analysis of Multi-Domain
Proteins." Angew. Chem. Int. Ed. Engl.,
56, 9322-9325. doi: 10.1002/anie.201702904.
|
Crystal structure of tia-1 rrm2 in complex with RNA .
SNAP output
|
|
5o58
|
hydrolase |
X-ray (1.55 Å) |
Drexler DJ, Muller M, Rojas-Cordova CA, Bandera AM,
Witte G |
(2017) "Structural
and Biophysical Analysis of the Soluble DHH/DHHA1-Type
Phosphodiesterase TM1595 from Thermotoga maritima."
Structure, 25, 1887-1897.e4.
doi: 10.1016/j.str.2017.10.001.
|
Structure of the inactive t.maritima pde (tm1595) d80n
d154n mutant with substrate 5'-papg . SNAP output
|
|
5o5j
|
ribosome |
cryo-EM (3.45 Å) |
Hentschel J, Burnside C, Mignot I, Leibundgut M,
Boehringer D, Ban N |
(2017) "The
Complete Structure of the Mycobacterium smegmatis 70S
Ribosome." Cell Rep, 20,
149-160. doi: 10.1016/j.celrep.2017.06.029.
|
Structure of the 30s small ribosomal subunit from
mycobacterium smegmatis . SNAP output
|
|
5o60
|
ribosome |
cryo-EM (3.18 Å) |
Hentschel J, Burnside C, Mignot I, Leibundgut M,
Boehringer D, Ban N |
(2017) "The
Complete Structure of the Mycobacterium smegmatis 70S
Ribosome." Cell Rep, 20,
149-160. doi: 10.1016/j.celrep.2017.06.029.
|
Structure of the 50s large ribosomal subunit from
mycobacterium smegmatis . SNAP output
|
|
5o61
|
ribosome |
cryo-EM (3.31 Å) |
Hentschel J, Burnside C, Mignot I, Leibundgut M,
Boehringer D, Ban N |
(2017) "The
Complete Structure of the Mycobacterium smegmatis 70S
Ribosome." Cell Rep, 20,
149-160. doi: 10.1016/j.celrep.2017.06.029.
|
The complete structure of the mycobacterium smegmatis
70s ribosome . SNAP
output
|
|
5o7h
|
antiviral protein |
X-ray (3.0 Å) |
Pausch P, Muller-Esparza H, Gleditzsch D, Altegoer F,
Randau L, Bange G |
(2017) "Structural
Variation of Type I-F CRISPR RNA Guided DNA
Surveillance." Mol. Cell,
67, 622-632.e4. doi: 10.1016/j.molcel.2017.06.036.
|
Structure of the cascade-i-fv complex from shewanella
putrefaciens . SNAP
output
|
|
5o9z
|
splicing |
cryo-EM (4.5 Å) |
Bertram K, Agafonov DE, Dybkov O, Haselbach D,
Leelaram MN, Will CL, Urlaub H, Kastner B, Luhrmann R,
Stark H |
(2017) "Cryo-EM
Structure of a Pre-catalytic Human Spliceosome Primed
for Activation." Cell,
170, 701-713.e11. doi: 10.1016/j.cell.2017.07.011.
|
cryo-EM structure of a pre-catalytic human spliceosome
primed for activation (b complex) . SNAP output
|
|
5oa3
|
translation |
cryo-EM (4.2 Å) |
Weisser M, Schafer T, Leibundgut M, Bohringer D,
Aylett CHS, Ban N |
(2017) "Structural
and Functional Insights into Human Re-initiation
Complexes." Mol. Cell,
67, 447-456.e7. doi: 10.1016/j.molcel.2017.06.032.
|
Human 40s-eif2d-re-initiation complex . SNAP output
|
|
5obm
|
ribosome |
X-ray (3.4 Å) |
Prokhorova I, Altman RB, Djumagulov M, Shrestha JP,
Urzhumtsev A, Ferguson A, Chang CT, Yusupov M, Blanchard
SC, Yusupova G |
(2017) "Aminoglycoside
interactions and impacts on the eukaryotic
ribosome." Proc. Natl. Acad. Sci. U.S.A.,
114, E10899-E10908. doi: 10.1073/pnas.1715501114.
|
Crystal structure of gentamicin bound to the yeast 80s
ribosome . SNAP
output
|
|
5oc6
|
RNA binding protein |
X-ray (3.2 Å) |
Bou-Nader C, Barraud P, Pecqueur L, Perez J, Velours
C, Shepard W, Fontecave M, Tisne C, Hamdane D |
(2019) "Molecular
basis for transfer RNA recognition by the
double-stranded RNA-binding domain of human
dihydrouridine synthase 2." Nucleic Acids
Res., 47, 3117-3126. doi:
10.1093/nar/gky1302.
|
Crystal structure of human trna-dihydrouridine(20)
synthase dsrbd in complex with a 22 nucleotide dsrna .
SNAP output
|
|
5odv
|
virus |
cryo-EM (4.0 Å) |
Zamora M, Mendez-Lopez E, Agirrezabala X, Cuesta R,
Lavin JL, Sanchez-Pina MA, Aranda MA, Valle M |
(2017) "Potyvirus
virion structure shows conserved protein fold and RNA
binding site in ssRNA viruses." Sci Adv,
3, eaao2182. doi: 10.1126/sciadv.aao2182.
|
Structure of watermelon mosaic virus potyvirus. .
SNAP output
|
|
5omw
|
translation |
X-ray (2.6 Å) |
Dulic M, Cvetesic N, Zivkovic I, Palencia A, Cusack
S, Bertosa B, Gruic-Sovulj I |
(2018) "Kinetic
Origin of Substrate Specificity in Post-Transfer
Editing by Leucyl-tRNA Synthetase." J. Mol.
Biol., 430, 1-16. doi: 10.1016/j.jmb.2017.10.024.
|
Mutant t252a of e. coli leucyl-trna synthetase,
trna(leu) and leucyl-adenylate analogue in the
aminoacylation conformation . SNAP output
|
|
5on2
|
translation |
X-ray (3.1 Å) |
Dulic M, Cvetesic N, Zivkovic I, Palencia A, Cusack
S, Bertosa B, Gruic-Sovulj I |
(2018) "Kinetic
Origin of Substrate Specificity in Post-Transfer
Editing by Leucyl-tRNA Synthetase." J. Mol.
Biol., 430, 1-16. doi: 10.1016/j.jmb.2017.10.024.
|
Quaternary complex of mutant t252a of e. coli
leucyl-trna synthetase with trna(leu), leucyl-adenylate
analogue, and post-transfer editing analogue of
norvaline in the aminoacylation conformation . SNAP output
|
|
5on3
|
ligase |
X-ray (3.1 Å) |
Dulic M, Cvetesic N, Zivkovic I, Palencia A, Cusack
S, Bertosa B, Gruic-Sovulj I |
(2018) "Kinetic
Origin of Substrate Specificity in Post-Transfer
Editing by Leucyl-tRNA Synthetase." J. Mol.
Biol., 430, 1-16. doi: 10.1016/j.jmb.2017.10.024.
|
Quaternary complex of mutant t252a of e. coli
leucyl-trna synthetase with trna(leu), leucyl-adenylate
analogue, and post-transfer editing analogue of leucine
in the aminoacylation conformation . SNAP output
|
|
5on6
|
ribosome |
X-ray (3.1 Å) |
Pellegrino S, Meyer M, Zorbas C, Bouchta SA, Saraf K,
Pelly SC, Yusupova G, Evidente A, Mathieu V, Kornienko A,
Lafontaine DLJ, Yusupov M |
(2018) "The
Amaryllidaceae Alkaloid Haemanthamine Binds the
Eukaryotic Ribosome to Repress Cancer Cell Growth."
Structure, 26, 416-425.e4.
doi: 10.1016/j.str.2018.01.009.
|
Crystal structure of haemanthamine bound to the 80s
ribosome . SNAP
output
|
|
5onh
|
ligase |
X-ray (3.1 Å) |
Dulic M, Cvetesic N, Zivkovic I, Palencia A, Cusack
S, Bertosa B, Gruic-Sovulj I |
(2018) "Kinetic
Origin of Substrate Specificity in Post-Transfer
Editing by Leucyl-tRNA Synthetase." J. Mol.
Biol., 430, 1-16. doi: 10.1016/j.jmb.2017.10.024.
|
Quaternary complex of wild type e. coli leucyl-trna
synthetase with trna(leu), leucyl-adenylate analogue,
and post-transfer editing analogue of norvaline in the
aminoacylation conformation . SNAP output
|
|
5ool
|
ribosome |
cryo-EM (3.06 Å) |
Brown A, Rathore S, Kimanius D, Aibara S, Bai XC,
Rorbach J, Amunts A, Ramakrishnan V |
(2017) "Structures
of the human mitochondrial ribosome in native states of
assembly." Nat. Struct. Mol. Biol.,
24, 866-869. doi: 10.1038/nsmb.3464.
|
Structure of a native assembly intermediate of the
human mitochondrial ribosome with unfolded interfacial
rrna . SNAP output
|
|
5oom
|
ribosome |
cryo-EM (3.03 Å) |
Brown A, Rathore S, Kimanius D, Aibara S, Bai XC,
Rorbach J, Amunts A, Ramakrishnan V |
(2017) "Structures
of the human mitochondrial ribosome in native states of
assembly." Nat. Struct. Mol. Biol.,
24, 866-869. doi: 10.1038/nsmb.3464.
|
Structure of a native assembly intermediate of the
human mitochondrial ribosome with unfolded interfacial
rrna . SNAP output
|
|
5opt
|
ribosome |
cryo-EM (4.0 Å) |
Brito Querido J, Mancera-Martinez E, Vicens Q,
Bochler A, Chicher J, Simonetti A, Hashem Y |
(2017) "The
cryo-EM Structure of a Novel 40S Kinetoplastid-Specific
Ribosomal Protein." Structure,
25, 1785-1794.e3. doi: 10.1016/j.str.2017.09.014.
|
Structure of ksrp in context of trypanosoma cruzi 40s .
SNAP output
|
|
5oql
|
ribosome |
cryo-EM (3.2 Å) |
Cheng J, Kellner N, Berninghausen O, Hurt E, Beckmann
R |
(2017) "3.2-
angstrom -resolution structure of the 90S preribosome
before A1 pre-rRNA cleavage." Nat. Struct. Mol.
Biol., 24, 954-964. doi: 10.1038/nsmb.3476.
|
cryo-EM structure of the 90s pre-ribosome from
chaetomium thermophilum . SNAP output
|
|
5osg
|
ribosome |
cryo-EM (2.9 Å) |
Brito Querido J, Mancera-Martinez E, Vicens Q,
Bochler A, Chicher J, Simonetti A, Hashem Y |
(2017) "The
cryo-EM Structure of a Novel 40S Kinetoplastid-Specific
Ribosomal Protein." Structure,
25, 1785-1794.e3. doi: 10.1016/j.str.2017.09.014.
|
Structure of ksrp in context of leishmania donovani 80s
. SNAP output
|
|
5ot7
|
ribosome |
cryo-EM (3.8 Å) |
Mace K, Giudice E, Chat S, Gillet R |
(2018) "The
structure of an elongation factor G-ribosome complex
captured in the absence of inhibitors." Nucleic
Acids Res., 46, 3211-3217. doi:
10.1093/nar/gky081.
|
Elongation factor g-ribosome complex captures in the
absence of inhibitors. . SNAP output
|
|
5sup
|
hydrolase-RNA |
X-ray (2.6 Å) |
Ren Y, Schmiege P, Blobel G |
(2017) "Structural
and biochemical analyses of the DEAD-box ATPase Sub2 in
association with THO or Yra1." Elife,
6. doi: 10.7554/eLife.20070.
|
Crystal structure of the sub2-yra1 complex in
association with RNA . SNAP output
|
|
5sze
|
RNA-binding protein-RNA |
X-ray (1.5 Å) |
Stanek KA, Patterson-West J, Randolph PS, Mura C |
(2017) "Crystal
structure and RNA-binding properties of an Hfq homolog
from the deep-branching Aquificae: conservation of the
lateral RNA-binding mode." Acta Crystallogr D
Struct Biol, 73, 294-315. doi:
10.1107/S2059798317000031.
|
Crystal structure of aquifex aeolicus hfq-RNA complex
at 1.5a . SNAP
output
|
|
5t16
|
hydrolase-RNA |
X-ray (2.783 Å) |
Song H, Fang X, Jin L, Shaw GX, Wang YX, Ji X |
(2017) "The
Functional Cycle of Rnt1p: Five Consecutive Steps of
Double-Stranded RNA Processing by a Eukaryotic RNase
III." Structure, 25,
353-363. doi: 10.1016/j.str.2016.12.013.
|
Crystal structure of yeast rnase iii (rnt1p) complexed
with a non-hydrolyzable RNA substrate analog . SNAP output
|
|
5t2a
|
ribosome |
cryo-EM (2.9 Å) |
Zhang X, Lai M, Chang W, Yu I, Ding K, Mrazek J, Ng
HL, Yang OO, Maslov DA, Zhou ZH |
(2016) "Structures
and stabilization of kinetoplastid-specific split rRNAs
revealed by comparing leishmanial and human
ribosomes." Nat Commun,
7, 13223. doi: 10.1038/ncomms13223.
|
Cryoem structure of the leishmania donovani 80s
ribosome at 2.9 angstrom resolution . SNAP output
|
|
5t5h
|
ribosome |
cryo-EM (2.54 Å) |
Liu Z, Gutierrez-Vargas C, Wei J, Grassucci RA,
Ramesh M, Espina N, Sun M, Tutuncuoglu B,
Madison-Antenucci S, Woolford JL, Tong L, Frank J |
(2016) "Structure
and assembly model for the Trypanosoma cruzi 60S
ribosomal subunit."
Proc.Natl.Acad.Sci.USA, 113,
12174-12179. doi: 10.1073/pnas.1614594113.
|
Structure and assembly model for the trypanosoma cruzi
60s ribosomal subunit . SNAP output
|
|
5t62
|
ribosome |
cryo-EM (3.1 Å) |
Malyutin AG, Musalgaonkar S, Patchett S, Frank J,
Johnson AW |
(2017) "Nmd3 is
a structural mimic of eIF5A, and activates the cpGTPase
Lsg1 during 60S ribosome biogenesis." EMBO
J., 36, 854-868. doi: 10.15252/embj.201696012.
|
Nmd3 is a structural mimic of eif5a, and activates the
cpgtpase lsg1 during 60s ribosome biogenesis:
60s-nmd3-tif6-lsg1 complex . SNAP output
|
|
5t6r
|
ribosome |
cryo-EM (4.2 Å) |
Malyutin AG, Musalgaonkar S, Patchett S, Frank J,
Johnson AW |
(2017) "Nmd3 is
a structural mimic of eIF5A, and activates the cpGTPase
Lsg1 during 60S ribosome biogenesis." EMBO
J., 36, 854-868. doi: 10.15252/embj.201696012.
|
Nmd3 is a structural mimic of eif5a, and activates the
cpgtpase lsg1 during 60s ribosome biogenesis: 60s-nmd3
complex . SNAP
output
|
|
5t7b
|
hydrolase-RNA |
X-ray (2.529 Å) |
Elkayam E, Joshua-Tor L |
"Protein structure." |
Argonaute-2 - 5'-(e)-vinylphosphonate
2'-o-methyl-uridine modified mrttr guide RNA complex .
SNAP output
|
|
5t7v
|
ribosome |
cryo-EM (3.6 Å) |
Belousoff MJ, Eyal Z, Radjainia M, Ahmed T, Bamert
RS, Matzov D, Bashan A, Zimmerman E, Mishra S, Cameron D,
Elmlund H, Peleg AY, Bhushan S, Lithgow T, Yonath A |
(2017) "Structural
Basis for Linezolid Binding Site Rearrangement in
theStaphylococcus aureusRibosome." MBio,
8. doi: 10.1128/mBio.00395-17.
|
Methicillin resistant, linezolid resistant
staphylococcus aureus 70s ribosome (delta s145 ul3) .
SNAP output
|
|
5t8y
|
oxidoreductase-RNA |
X-ray (2.653 Å) |
Dowling DP, Miles ZD, Kohrer C, Maiocco SJ, Elliott
SJ, Bandarian V, Drennan CL |
(2016) "Molecular
basis of cobalamin-dependent RNA modification."
Nucleic Acids Res., 44,
9965-9976. doi: 10.1093/nar/gkw806.
|
Structure of epoxyqueuosine reductase from bacillus
subtilis with the asp134 catalytic loop swung out of
the active site. . SNAP
output
|
|
5tbw
|
ribosome |
X-ray (3.0 Å) |
Konst ZA, Szklarski AR, Pellegrino S, Michalak SE,
Meyer M, Zanette C, Cencic R, Nam S, Voora VK, Horne DA,
Pelletier J, Mobley DL, Yusupova G, Yusupov M, Vanderwal
CD |
(2017) "Synthesis
facilitates an understanding of the structural basis
for translation inhibition by the lissoclimides."
Nat Chem, 9, 1140-1149. doi:
10.1038/nchem.2800.
|
Crystal structure of chlorolissoclimide bound to the
yeast 80s ribosome . SNAP output
|
|
5tc1
|
viral protein-RNA |
cryo-EM (3.6 Å) |
Dai X, Li Z, Lai M, Shu S, Du Y, Zhou ZH, Sun R |
(2017) "In situ
structures of the genome and genome-delivery apparatus
in a single-stranded RNA virus." Nature,
541, 112-116. doi: 10.1038/nature20589.
|
In situ structures of the genome and genome-delivery
apparatus in ssrna bacteriophage ms2 . SNAP output
|
|
5tcu
|
ribosome-antibiotic |
cryo-EM (3.9 Å) |
Belousoff MJ, Eyal Z, Radjainia M, Ahmed T, Bamert
RS, Matzov D, Bashan A, Zimmerman E, Mishra S, Cameron D,
Elmlund H, Peleg AY, Bhushan S, Lithgow T, Yonath A |
(2017) "Structural
Basis for Linezolid Binding Site Rearrangement in the
Staphylococcus aureus Ribosome." MBio,
8. doi: 10.1128/mBio.00395-17.
|
Methicillin sensitive staphylococcus aureus 70s
ribosome . SNAP
output
|
|
5tf6
|
RNA binding protein-RNA |
X-ray (2.3 Å) |
Montemayor EJ, Didychuk AL, Liao H, Hu P, Brow DA,
Butcher SE |
(2017) "Structure
and conformational plasticity of the U6 small nuclear
ribonucleoprotein core." Acta Crystallogr D
Struct Biol, 73, 1-8. doi:
10.1107/S2059798316018222.
|
Structure and conformational plasticity of the u6 small
nuclear ribonucleoprotein core . SNAP output
|
|
5tga
|
ribosome |
X-ray (3.3 Å) |
Melnikov S, Mailliot J, Rigger L, Neuner S, Shin BS,
Yusupova G, Dever TE, Micura R, Yusupov M |
(2016) "Molecular
insights into protein synthesis with proline
residues." EMBO Rep., 17,
1776-1784. doi: 10.15252/embr.201642943.
|
Crystal structure of the s.cerevisiae 80s ribosome in
complex with the a-site bound aminoacyl-trna analog
acca-pro . SNAP
output
|
|
5tgm
|
ribosome |
X-ray (3.5 Å) |
Melnikov S, Mailliot J, Rigger L, Neuner S, Shin BS,
Yusupova G, Dever TE, Micura R, Yusupov M |
(2016) "Molecular
insights into protein synthesis with proline
residues." EMBO Rep., 17,
1776-1784. doi: 10.15252/embr.201642943.
|
Crystal structure of the s.cerevisiae 80s ribosome in
complex with the a-site bound aminoacyl-trna analog
acca-pro . SNAP
output
|
|
5the
|
RNA binding protein-RNA |
X-ray (2.097 Å) |
Dayeh DM, Kruithoff BC, Nakanishi K |
(2018) "Structural
and functional analyses reveal the contributions of the
C- and N-lobes of Argonaute protein to selectivity of
RNA target cleavage." J. Biol. Chem.,
293, 6308-6325. doi: 10.1074/jbc.RA117.001051.
|
Crystal structure of the c-terminal lobe of a budding
yeast argonaute . SNAP
output
|
|
5tsn
|
transferase-RNA |
X-ray (2.1 Å) |
Shaik MM, Bhattacharjee N, Feliks M, Ng KK, Field
MJ |
(2017) "Norovirus
RNA-dependent RNA polymerase: A computational study of
metal-binding preferences." Proteins,
85, 1435-1445. doi: 10.1002/prot.25304.
|
Crystal structures of norwalk virus polymerase bound to
an RNA primer-template duplex . SNAP output
|
|
5tzs
|
translation |
cryo-EM (5.1 Å) |
Chaker-Margot M, Barandun J, Hunziker M, Klinge
S |
(2017) "Architecture
of the yeast small subunit processome."
Science, 355. doi: 10.1126/science.aal1880.
|
Architecture of the yeast small subunit processome .
SNAP output
|
|
5u34
|
hydrolase-RNA |
X-ray (3.255 Å) |
Yang H, Gao P, Rajashankar KR, Patel DJ |
(2016) "PAM-Dependent
Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas
Endonuclease." Cell, 167,
1814-1828.e12. doi: 10.1016/j.cell.2016.11.053.
|
Crystal structure of aacc2c1-sgrna binary complex .
SNAP output
|
|
5u4i
|
ribosome |
cryo-EM (3.5 Å) |
Zeng F, Chen Y, Remis J, Shekhar M, Phillips JC,
Tajkhorshid E, Jin H |
(2017) "Structural
basis of co-translational quality control by ArfA and
RF2 bound to ribosome." Nature,
541, 554-557. doi: 10.1038/nature21053.
|
Structural basis of co-translational quality control by
arfa and rf2 bound to ribosome . SNAP output
|
|
5u4j
|
ribosome |
cryo-EM (3.7 Å) |
Zeng F, Chen Y, Remis J, Shekhar M, Phillips JC,
Tajkhorshid E, Jin H |
(2017) "Structural
basis of co-translational quality control by ArfA and
RF2 bound to ribosome." Nature,
541, 554-557. doi: 10.1038/nature21053.
|
Structural basis of co-translational quality control by
arfa and rf2 bound to ribosome . SNAP output
|
|
5u9b
|
RNA binding protein-RNA |
NMR |
Park S, Phukan PD, Zeeb M, Martinez-Yamout MA, Dyson
HJ, Wright PE |
(2017) "Structural
Basis for Interaction of the Tandem Zinc Finger Domains
of Human Muscleblind with Cognate RNA from Human
Cardiac Troponin T." Biochemistry,
56, 4154-4168. doi: 10.1021/acs.biochem.7b00484.
|
Solution structure of the zinc fingers 1 and 2 of mbnl1
in complex with human cardiac troponin t pre-mrna .
SNAP output
|
|
5u9f
|
ribosome |
cryo-EM (3.2 Å) |
Demo G, Svidritskiy E, Madireddy R, Diaz-Avalos R,
Grant T, Grigorieff N, Sousa D, Korostelev AA |
(2017) "Mechanism
of ribosome rescue by ArfA and RF2."
Elife, 6. doi: 10.7554/eLife.23687.
|
3.2 a cryo-EM arfa-rf2 ribosome rescue complex
(structure ii) . SNAP
output
|
|
5u9g
|
ribosome |
cryo-EM (3.2 Å) |
Demo G, Svidritskiy E, Madireddy R, Diaz-Avalos R,
Grant T, Grigorieff N, Sousa D, Korostelev AA |
(2017) "Mechanism
of ribosome rescue by ArfA and RF2."
Elife, 6. doi: 10.7554/eLife.23687.
|
3.2 a cryo-EM arfa-rf2 ribosome rescue complex
(structure i) . SNAP
output
|
|
5ud5
|
ligase-RNA |
X-ray (2.347 Å) |
Suzuki T, Miller C, Guo LT, Ho JML, Bryson DI, Wang
YS, Liu DR, Soll D |
(2017) "Crystal
structures reveal an elusive functional domain of
pyrrolysyl-tRNA synthetase." Nat. Chem.
Biol., 13, 1261-1266. doi:
10.1038/nchembio.2497.
|
Crystal structure of the trna binding domain of
pyrrolysyl-trna synthetase bound to trna(pyl) .
SNAP output
|
|
5udi
|
RNA binding protein |
X-ray (1.58 Å) |
Abbas YM, Laudenbach BT, Martinez-Montero S, Cencic
R, Habjan M, Pichlmair A, Damha MJ, Pelletier J, Nagar
B |
(2017) "Structure
of human IFIT1 with capped RNA reveals adaptable mRNA
binding and mechanisms for sensing N1 and N2 ribose
2'-O methylations." Proc. Natl. Acad. Sci.
U.S.A., 114, E2106-E2115. doi:
10.1073/pnas.1612444114.
|
Ifit1 monomeric mutant (l457e-l464e) with m7gppp-aaaa
(syn and anti conformations of cap) . SNAP output
|
|
5udj
|
RNA binding protein |
X-ray (1.69 Å) |
Abbas YM, Laudenbach BT, Martinez-Montero S, Cencic
R, Habjan M, Pichlmair A, Damha MJ, Pelletier J, Nagar
B |
(2017) "Structure
of human IFIT1 with capped RNA reveals adaptable mRNA
binding and mechanisms for sensing N1 and N2 ribose
2'-O methylations." Proc. Natl. Acad. Sci.
U.S.A., 114, E2106-E2115. doi:
10.1073/pnas.1612444114.
|
Ifit1 monomeric mutant (l457e-l464e) with gppp-aaaa .
SNAP output
|
|
5udk
|
RNA binding protein |
X-ray (1.65 Å) |
Abbas YM, Laudenbach BT, Martinez-Montero S, Cencic
R, Habjan M, Pichlmair A, Damha MJ, Pelletier J, Nagar
B |
(2017) "Structure
of human IFIT1 with capped RNA reveals adaptable mRNA
binding and mechanisms for sensing N1 and N2 ribose
2'-O methylations." Proc. Natl. Acad. Sci.
U.S.A., 114, E2106-E2115. doi:
10.1073/pnas.1612444114.
|
Ifit1 monomeric mutant (l457e-l464e) with ppp-aaaa .
SNAP output
|
|
5udl
|
RNA binding protein |
X-ray (1.65 Å) |
Abbas YM, Laudenbach BT, Martinez-Montero S, Cencic
R, Habjan M, Pichlmair A, Damha MJ, Pelletier J, Nagar
B |
(2017) "Structure
of human IFIT1 with capped RNA reveals adaptable mRNA
binding and mechanisms for sensing N1 and N2 ribose
2'-O methylations." Proc. Natl. Acad. Sci.
U.S.A., 114, E2106-E2115. doi:
10.1073/pnas.1612444114.
|
Ifit1 n216a monomeric mutant (l457e-l464e) with
m7gppp-aaaa (anti conformation of cap) . SNAP output
|
|
5udz
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Wang L, Nam Y, Lee AK, Yu C, Roth K, Chen C, Ransey
EM, Sliz P |
(2017) "LIN28
Zinc Knuckle Domain Is Required and Sufficient to
Induce let-7 Oligouridylation." Cell Rep,
18, 2664-2675. doi: 10.1016/j.celrep.2017.02.044.
|
Human lin28a in complex with let-7f-1 microrna
pre-element . SNAP
output
|
|
5uk4
|
viral protein-RNA-immune system |
X-ray (3.204 Å) |
Hanke L, Schmidt FI, Knockenhauer KE, Morin B, Whelan
SP, Schwartz TU, Ploegh HL |
(2017) "Vesicular
stomatitis virus N protein-specific single-domain
antibody fragments inhibit replication." EMBO
Rep., 18, 1027-1037. doi:
10.15252/embr.201643764.
|
Vesicular stomatits virus n protein in complex with
inhibitory nanobody 1307 . SNAP output
|
|
5ukb
|
viral protein-RNA-immune system |
X-ray (5.473 Å) |
Hanke L, Schmidt FI, Knockenhauer KE, Morin B, Whelan
SP, Schwartz TU, Ploegh HL |
(2017) "Vesicular
stomatitis virus N protein-specific single-domain
antibody fragments inhibit replication." EMBO
Rep., 18, 1027-1037. doi:
10.15252/embr.201643764.
|
Vsv n protein in complex with inhibitory nanobody 1004
. SNAP output
|
|
5umd
|
ribosome |
cryo-EM (3.2 Å) |
Wong W, Bai XC, Sleebs BE, Triglia T, Brown A,
Thompson JK, Jackson KE, Hanssen E, Marapana DS,
Fernandez IS, Ralph SA, Cowman AF, Scheres SH, Baum
J |
(2017) "Mefloquine
targets the Plasmodium falciparum 80S ribosome to
inhibit protein synthesis." Nat Microbiol,
2, 17031. doi: 10.1038/nmicrobiol.2017.31.
|
Structure of the plasmodium falciparum 80s ribosome
bound to the antimalarial drug mefloquine . SNAP output
|
|
5uq7
|
ribosome |
cryo-EM (3.5 Å) |
Zhang Y, Hong S, Ruangprasert A, Skiniotis G, Dunham
CM |
(2018) "Alternative
Mode of E-Site tRNA Binding in the Presence of a
Downstream mRNA Stem Loop at the Entrance Channel."
Structure, 26, 437-445.e3.
doi: 10.1016/j.str.2018.01.013.
|
70s ribosome complex with dnax mrna stemloop and e-site
trna ("in" conformation) . SNAP output
|
|
5uq8
|
ribosome |
cryo-EM (3.2 Å) |
Zhang Y, Hong S, Ruangprasert A, Skiniotis G, Dunham
CM |
(2018) "Alternative
Mode of E-Site tRNA Binding in the Presence of a
Downstream mRNA Stem Loop at the Entrance Channel."
Structure, 26, 437-445.e3.
doi: 10.1016/j.str.2018.01.013.
|
70s ribosome complex with dnax mrna stem-loop and
e-site trna ("out" conformation) . SNAP output
|
|
5uyk
|
ribosome |
cryo-EM (3.9 Å) |
Loveland AB, Demo G, Grigorieff N, Korostelev AA |
(2017) "Ensemble
cryo-EM elucidates the mechanism of translation
fidelity." Nature, 546,
113-117. doi: 10.1038/nature22397.
|
70s ribosome bound with cognate ternary complex not
base-paired to a site codon (structure i) . SNAP output
|
|
5uyl
|
ribosome |
cryo-EM (3.6 Å) |
Loveland AB, Demo G, Grigorieff N, Korostelev AA |
(2017) "Ensemble
cryo-EM elucidates the mechanism of translation
fidelity." Nature, 546,
113-117. doi: 10.1038/nature22397.
|
70s ribosome bound with cognate ternary complex
base-paired to a site codon (structure ii) . SNAP output
|
|
5uym
|
ribosome |
cryo-EM (3.2 Å) |
Loveland AB, Demo G, Grigorieff N, Korostelev AA |
(2017) "Ensemble
cryo-EM elucidates the mechanism of translation
fidelity." Nature, 546,
113-117. doi: 10.1038/nature22397.
|
70s ribosome bound with cognate ternary complex
base-paired to a site codon, closed 30s (structure iii)
. SNAP output
|
|
5uyn
|
ribosome |
cryo-EM (4.0 Å) |
Loveland AB, Demo G, Grigorieff N, Korostelev AA |
(2017) "Ensemble
cryo-EM elucidates the mechanism of translation
fidelity." Nature, 546,
113-117. doi: 10.1038/nature22397.
|
70s ribosome bound with near-cognate ternary complex
not base-paired to a site codon (structure i-nc) .
SNAP output
|
|
5uyp
|
ribosome |
cryo-EM (3.9 Å) |
Loveland AB, Demo G, Grigorieff N, Korostelev AA |
(2017) "Ensemble
cryo-EM elucidates the mechanism of translation
fidelity." Nature, 546,
113-117. doi: 10.1038/nature22397.
|
70s ribosome bound with near-cognate ternary complex
base-paired to a site codon, open 30s (structure ii-nc)
. SNAP output
|
|
5uyq
|
ribosome |
cryo-EM (3.8 Å) |
Loveland AB, Demo G, Grigorieff N, Korostelev AA |
(2017) "Ensemble
cryo-EM elucidates the mechanism of translation
fidelity." Nature, 546,
113-117. doi: 10.1038/nature22397.
|
70s ribosome bound with near-cognate ternary complex
base-paired to a site codon, closed 30s (structure
iii-nc) . SNAP
output
|
|
5uz4
|
ribosome-hydrolase |
cryo-EM (5.8 Å) |
Razi A, Guarne A, Ortega J |
(2017) "The
cryo-EM structure of YjeQ bound to the 30S subunit
suggests a fidelity checkpoint function for this
protein in ribosome assembly." Proc. Natl.
Acad. Sci. U.S.A., 114,
E3396-E3403. doi: 10.1073/pnas.1618016114.
|
The cryo-EM structure of yjeq bound to the 30s subunit
suggests a fidelity checkpoint function for this
protein in ribosome assembly . SNAP output
|
|
5uz9
|
immune system-RNA |
cryo-EM (3.4 Å) |
Chowdhury S, Carter J, Rollins MF, Golden SM, Jackson
RN, Hoffmann C, Nosaka L, Bondy-Denomy J, Maxwell KL,
Davidson AR, Fischer ER, Lander GC, Wiedenheft B |
(2017) "Structure
Reveals Mechanisms of Viral Suppressors that Intercept
a CRISPR RNA-Guided Surveillance Complex."
Cell, 169, 47-57.e11. doi:
10.1016/j.cell.2017.03.012.
|
Cryo em structure of anti-crisprs, acrf1 and acrf2,
bound to type i-f crrna-guided crispr surveillance
complex . SNAP
output
|
|
5uzz
|
transport protein-RNA |
NMR |
Shortridge MD, Walker MJ, Pavelitz T, Chen Y, Yang W,
Varani G |
(2017) "A
Macrocyclic Peptide Ligand Binds the Oncogenic
MicroRNA-21 Precursor and Suppresses Dicer
Processing." ACS Chem. Biol.,
12, 1611-1620. doi: 10.1021/acschembio.7b00180.
|
Structure of wild type pre-mir21 apical loop . SNAP output
|
|
5v6x
|
ligase-RNA |
X-ray (2.76 Å) |
Suzuki T, Miller C, Guo LT, Ho JML, Bryson DI, Wang
YS, Liu DR, Soll D |
(2017) "Crystal
structures reveal an elusive functional domain of
pyrrolysyl-tRNA synthetase." Nat. Chem.
Biol., 13, 1261-1266. doi:
10.1038/nchembio.2497.
|
Crystal structure of the trna binding domain of
pyrrolysyl-trna synthetase mutant (32a ntd) bound to
trna(pyl) . SNAP
output
|
|
5v7c
|
RNA binding protein |
X-ray (2.59 Å) |
Lahr RM, Fonseca BD, Ciotti GE, Al-Ashtal HA, Jia JJ,
Niklaus MR, Blagden SP, Alain T, Berman AJ |
(2017) "La-related
protein 1 (LARP1) binds the mRNA cap, blocking eIF4F
assembly on TOP mRNAs." Elife,
6. doi: 10.7554/eLife.24146.
|
Crystal structure of larp1-unique domain dm15 bound
5'top RNA sequence . SNAP output
|
|
5v7q
|
ribosome |
cryo-EM (3.7 Å) |
Yang K, Chang JY, Cui Z, Li X, Meng R, Duan L,
Thongchol J, Jakana J, Huwe CM, Sacchettini JC, Zhang
J |
(2017) "Structural
insights into species-specific features of the ribosome
from the human pathogen Mycobacterium
tuberculosis." Nucleic Acids Res.,
45, 10884-10894. doi: 10.1093/nar/gkx785.
|
cryo-EM structure of the large ribosomal subunit from
mycobacterium tuberculosis bound with a potent
linezolid analog . SNAP
output
|
|
5v8i
|
ribosome |
X-ray (3.25 Å) |
Murphy E, Connetti JL, Dahlberg AE, Gregory ST, Jogl
G |
"Structural robustness of the ribosome inferred from
X-ray crystal structures of the 30S ribosomal subunit and
the 70S ribosome lacking ribosomal protein uS17." |
Thermus thermophilus 70s ribosome lacking ribosomal
protein us17 . SNAP
output
|
|
5v93
|
ribosome |
cryo-EM (4.0 Å) |
Yang K, Chang JY, Cui Z, Li X, Meng R, Duan L,
Thongchol J, Jakana J, Huwe CM, Sacchettini JC, Zhang
J |
(2017) "Structural
insights into species-specific features of the ribosome
from the human pathogen Mycobacterium
tuberculosis." Nucleic Acids Res.,
45, 10884-10894. doi: 10.1093/nar/gkx785.
|
cryo-EM structure of the 70s ribosome from
mycobacterium tuberculosis bound with capreomycin .
SNAP output
|
|
5vm9
|
hydrolase-RNA |
X-ray (3.28 Å) |
Park MS, Phan HD, Busch F, Hinckley SH, Brackbill JA,
Wysocki VH, Nakanishi K |
(2017) "Human
Argonaute3 has slicer activity." Nucleic Acids
Res., 45, 11867-11877. doi:
10.1093/nar/gkx916.
|
Human argonaute3 bound to guide RNA . SNAP output
|
|
5voe
|
hydrolase-RNA |
X-ray (2.0 Å) |
Gunaratne R, Kumar S, Frederiksen JW, Stayrook S,
Lohrmann JL, Perry K, Bompiani KM, Chabata CV, Thalji NK,
Ho MD, Arepally G, Camire RM, Krishnaswamy S, Sullenger
BA |
(2018) "Combination
of aptamer and drug for reversible anticoagulation in
cardiopulmonary bypass." Nat. Biotechnol.,
36, 606-613. doi: 10.1038/nbt.4153.
|
Desgla-xas195a bound to aptamer 11f7t . SNAP output
|
|
5vof
|
hydrolase-hydrolase inhibitor-RNA |
X-ray (2.25 Å) |
Gunaratne R, Kumar S, Frederiksen JW, Stayrook S,
Lohrmann JL, Perry K, Bompiani KM, Chabata CV, Thalji NK,
Ho MD, Arepally G, Camire RM, Krishnaswamy S, Sullenger
BA |
(2018) "Combination
of aptamer and drug for reversible anticoagulation in
cardiopulmonary bypass." Nat. Biotechnol.,
36, 606-613. doi: 10.1038/nbt.4153.
|
Desgla-xas195a bound to aptamer 11f7t and rivaroxaban .
SNAP output
|
|
5vp2
|
ribosome |
X-ray (2.8 Å) |
Osterman IA, Khabibullina NF, Komarova ES, Kasatsky
P, Kartsev VG, Bogdanov AA, Dontsova OA, Konevega AL,
Sergiev PV, Polikanov YS |
(2017) "Madumycin
II inhibits peptide bond formation by forcing the
peptidyl transferase center into an inactive
state." Nucleic Acids Res.,
45, 7507-7514. doi: 10.1093/nar/gkx413.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with madumycin ii and bound to mrna
and a-, p- and e-site trnas at 2.8a resolution .
SNAP output
|
|
5vpo
|
ribosome |
X-ray (3.34 Å) |
Hong S, Sunita S, Maehigashi T, Hoffer ED, Dunkle JA,
Dunham CM |
(2018) "Mechanism
of tRNA-mediated +1 ribosomal frameshifting."
Proc. Natl. Acad. Sci. U.S.A.,
115, 11226-11231. doi: 10.1073/pnas.1809319115.
|
The 70s p-site asl sufa6 complex . SNAP output
|
|
5vpp
|
ribosome |
X-ray (3.9 Å) |
Hong S, Sunita S, Maehigashi T, Hoffer ED, Dunkle JA,
Dunham CM |
(2018) "Mechanism
of tRNA-mediated +1 ribosomal frameshifting."
Proc. Natl. Acad. Sci. U.S.A.,
115, 11226-11231. doi: 10.1073/pnas.1809319115.
|
The 70s p-site trna sufa6 complex . SNAP output
|
|
5vsu
|
splicing |
X-ray (3.1 Å) |
Montemayor EJ, Didychuk AL, Yake AD, Sidhu GK, Brow
DA, Butcher SE |
(2018) "Architecture
of the U6 snRNP reveals specific recognition of 3'-end
processed U6 snRNA." Nat Commun,
9, 1749. doi: 10.1038/s41467-018-04145-4.
|
Structure of yeast u6 snrnp with 2'-phosphate
terminated u6 RNA . SNAP
output
|
|
5vt0
|
transcription-RNA |
cryo-EM (3.78 Å) |
Chen J, Wassarman KM, Feng S, Leon K, Feklistov A,
Winkelman JT, Li Z, Walz T, Campbell EA, Darst SA |
(2017) "6S RNA
Mimics B-Form DNA to Regulate Escherichia coli RNA
Polymerase." Mol. Cell,
68, 388-397.e6. doi: 10.1016/j.molcel.2017.09.006.
|
Escherichia coli 6s RNA derivative in complex with
escherichia coli RNA polymerase sigma70-holoenzyme .
SNAP output
|
|
5vw1
|
hydrolase |
X-ray (2.598 Å) |
Yang H, Patel DJ |
(2017) "Inhibition
Mechanism of an Anti-CRISPR Suppressor AcrIIA4
Targeting SpyCas9." Mol. Cell,
67, 117-127.e5. doi: 10.1016/j.molcel.2017.05.024.
|
Crystal structure of spycas9-sgrna-acriia4 ternary
complex . SNAP
output
|
|
5vzj
|
hydrolase-RNA |
X-ray (3.3 Å) |
Wasmuth EV, Zinder JC, Zattas D, Das M, Lima CD |
(2017) "Structure
and reconstitution of yeast Mpp6-nuclear exosome
complexes reveals that Mpp6 stimulates RNA decay and
recruits the Mtr4 helicase." Elife,
6. doi: 10.7554/eLife.29062.
|
Structure of a twelve component mpp6-nuclear RNA
exosome complex bound to RNA . SNAP output
|
|
5vzl
|
immune system-RNA |
cryo-EM (3.9 Å) |
Shin J, Jiang F, Liu JJ, Bray NL, Rauch BJ, Baik SH,
Nogales E, Bondy-Denomy J, Corn JE, Doudna JA |
(2017) "Disabling
Cas9 by an anti-CRISPR DNA mimic." Sci
Adv, 3, e1701620. doi: 10.1126/sciadv.1701620.
|
cryo-EM structure of the cas9-sgrna-acriia4 anti-crispr
complex . SNAP
output
|
|
5w0m
|
transferase-RNA |
X-ray (2.298 Å) |
Faehnle CR, Walleshauser J, Joshua-Tor L |
(2017) "Multi-domain
utilization by TUT4 and TUT7 in control of let-7
biogenesis." Nat. Struct. Mol. Biol.,
24, 658-665. doi: 10.1038/nsmb.3428.
|
Structure of human tut7 catalytic module (cm) in
complex with u5 RNA . SNAP output
|
|
5w0o
|
transferase-RNA |
X-ray (2.488 Å) |
Faehnle CR, Walleshauser J, Joshua-Tor L |
(2017) "Multi-domain
utilization by TUT4 and TUT7 in control of let-7
biogenesis." Nat. Struct. Mol. Biol.,
24, 658-665. doi: 10.1038/nsmb.3428.
|
Structure of human tut7 catalytic module (cm) in
complex with dsrna . SNAP output
|
|
5w1h
|
RNA binding protein-RNA |
X-ray (1.99 Å) |
Knott GJ, East-Seletsky A, Cofsky JC, Holton JM,
Charles E, O'Connell MR, Doudna JA |
(2017) "Guide-bound
structures of an RNA-targeting A-cleaving CRISPR-Cas13a
enzyme." Nat. Struct. Mol. Biol.,
24, 825-833. doi: 10.1038/nsmb.3466.
|
Crystal structure of lbacas13a (c2c2) bound to mature
crrna (24-nt spacer) . SNAP output
|
|
5w3v
|
antiviral protein-RNA |
X-ray (2.243 Å) |
Bohn JA, Thummar K, York A, Raymond A, Brown WC,
Bieniasz PD, Hatziioannou T, Smith JL |
(2017) "APOBEC3H
structure reveals an unusual mechanism of interaction
with duplex RNA." Nat Commun,
8, 1021. doi: 10.1038/s41467-017-01309-6.
|
Crystal structure of macaque apobec3h in complex with
RNA . SNAP output
|
|
5w4k
|
ribosome-antibiotic |
X-ray (2.7 Å) |
Metelev M, Osterman IA, Ghilarov D, Khabibullina NF,
Yakimov A, Shabalin K, Utkina I, Travin DY, Komarova ES,
Serebryakova M, Artamonova T, Khodorkovskii M, Konevega
AL, Sergiev PV, Severinov K, Polikanov YS |
(2017) "Klebsazolicin
inhibits 70S ribosome by obstructing the peptide exit
tunnel." Nat. Chem. Biol.,
13, 1129-1136. doi: 10.1038/nchembio.2462.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with klebsazolicin and bound to
mrna and a-, p- and e-site trnas at 2.7a resolution .
SNAP output
|
|
5w5h
|
RNA binding protein-RNA |
X-ray (2.79 Å) |
Abbas YM, Martinez-Montero S, Cencic R, Pelletier J,
Damha MJ, Pawelek PD, Nagar B |
"Structural insights into IFIT1 dimerization and
conformational changes associated with mRNA
binding." |
Human ifit1 dimer with m7gppp-aaaa . SNAP output
|
|
5w5i
|
RNA binding protein-RNA |
X-ray (2.65 Å) |
Abbas YM, Martinez-Montero S, Cencic R, Pelletier J,
Damha MJ, Pawelek PD, Nagar B |
"Structural insights into IFIT1 dimerization and
conformational changes associated with mRNA
binding." |
Human ifit1 dimer with ppp-aaaa . SNAP output
|
|
5w6v
|
gene regulation-RNA |
X-ray (2.828 Å) |
Elkayam E, Faehnle CR, Morales M, Sun J, Li H,
Joshua-Tor L |
(2017) "Multivalent
Recruitment of Human Argonaute by GW182." Mol.
Cell, 67, 646-658.e3. doi:
10.1016/j.molcel.2017.07.007.
|
The structure of human argonaute-1 in complex with the
hook motif of human gw182 . SNAP output
|
|
5wdt
|
ribosome |
cryo-EM (3.0 Å) |
Fislage M, Zhang J, Brown ZP, Mandava CS, Sanyal S,
Ehrenberg M, Frank J |
(2018) "Cryo-EM
shows stages of initial codon selection on the ribosome
by aa-tRNA in ternary complex with GTP and the
GTPase-deficient EF-TuH84A." Nucleic Acids
Res., 46, 5861-5874. doi:
10.1093/nar/gky346.
|
70s ribosome-ef-tu h84a complex with gppnhp . SNAP output
|
|
5we4
|
ribosome |
cryo-EM (3.1 Å) |
Fislage M, Zhang J, Brown ZP, Mandava CS, Sanyal S,
Ehrenberg M, Frank J |
(2018) "Cryo-EM
shows stages of initial codon selection on the ribosome
by aa-tRNA in ternary complex with GTP and the
GTPase-deficient EF-TuH84A." Nucleic Acids
Res., 46, 5861-5874. doi:
10.1093/nar/gky346.
|
70s ribosome-ef-tu wt complex with gppnhp . SNAP output
|
|
5we6
|
ribosome |
cryo-EM (3.4 Å) |
Fislage M, Zhang J, Brown ZP, Mandava CS, Sanyal S,
Ehrenberg M, Frank J |
(2018) "Cryo-EM
shows stages of initial codon selection on the ribosome
by aa-tRNA in ternary complex with GTP and the
GTPase-deficient EF-TuH84A." Nucleic Acids
Res., 46, 5861-5874. doi:
10.1093/nar/gky346.
|
70s ribosome-ef-tu h84a complex with gtp and cognate
trna . SNAP output
|
|
5wea
|
hydrolase-RNA |
X-ray (3.12 Å) |
Klum SM, Chandradoss SD, Schirle NT, Joo C, MacRae
IJ |
(2018) "Helix-7
in Argonaute2 shapes the microRNA seed region for rapid
target recognition." EMBO J.,
37, 75-88. doi: 10.15252/embj.201796474.
|
Human argonaute2 helix-7 mutant . SNAP output
|
|
5wf0
|
ribosome |
cryo-EM (3.6 Å) |
Fislage M, Zhang J, Brown ZP, Mandava CS, Sanyal S,
Ehrenberg M, Frank J |
(2018) "Cryo-EM
shows stages of initial codon selection on the ribosome
by aa-tRNA in ternary complex with GTP and the
GTPase-deficient EF-TuH84A." Nucleic Acids
Res., 46, 5861-5874. doi:
10.1093/nar/gky346.
|
70s ribosome-ef-tu h84a complex with gtp and
near-cognate trna (complex c2) . SNAP output
|
|
5wfk
|
ribosome |
cryo-EM (3.4 Å) |
Fislage M, Zhang J, Brown ZP, Mandava CS, Sanyal S,
Ehrenberg M, Frank J |
(2018) "Cryo-EM
shows stages of initial codon selection on the ribosome
by aa-tRNA in ternary complex with GTP and the
GTPase-deficient EF-TuH84A." Nucleic Acids
Res., 46, 5861-5874. doi:
10.1093/nar/gky346.
|
70s ribosome-ef-tu h84a complex with gtp and
near-cognate trna (complex c3) . SNAP output
|
|
5wfs
|
ribosome |
cryo-EM (3.0 Å) |
Fislage M, Zhang J, Brown ZP, Mandava CS, Sanyal S,
Ehrenberg M, Frank J |
(2018) "Cryo-EM
shows stages of initial codon selection on the ribosome
by aa-tRNA in ternary complex with GTP and the
GTPase-deficient EF-TuH84A." Nucleic Acids
Res., 46, 5861-5874. doi:
10.1093/nar/gky346.
|
70s ribosome-ef-tu h84a complex with gtp and
near-cognate trna (complex c4) . SNAP output
|
|
5wis
|
ribosome |
X-ray (2.703 Å) |
Almutairi MM, Svetlov MS, Hansen DA, Khabibullina NF,
Klepacki D, Kang HY, Sherman DH, Vazquez-Laslop N,
Polikanov YS, Mankin AS |
(2017) "Co-produced
natural ketolides methymycin and pikromycin inhibit
bacterial growth by preventing synthesis of a limited
number of proteins." Nucleic Acids Res.,
45, 9573-9582. doi: 10.1093/nar/gkx673.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with methymycin and bound to mrna
and a-, p- and e-site trnas at 2.7a resolution .
SNAP output
|
|
5wit
|
ribosome |
X-ray (2.6 Å) |
Almutairi MM, Svetlov MS, Hansen DA, Khabibullina NF,
Klepacki D, Kang HY, Sherman DH, Vazquez-Laslop N,
Polikanov YS, Mankin AS |
(2017) "Co-produced
natural ketolides methymycin and pikromycin inhibit
bacterial growth by preventing synthesis of a limited
number of proteins." Nucleic Acids Res.,
45, 9573-9582. doi: 10.1093/nar/gkx673.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with pikromycin and bound to mrna
and a-, p- and e-site trnas at 2.6a resolution .
SNAP output
|
|
5wlc
|
ribosome |
cryo-EM (3.8 Å) |
Barandun J, Chaker-Margot M, Hunziker M, Molloy KR,
Chait BT, Klinge S |
(2017) "The
complete structure of the small-subunit
processome." Nat. Struct. Mol. Biol.,
24, 944-953. doi: 10.1038/nsmb.3472.
|
The complete structure of the small subunit processome
. SNAP output
|
|
5wlh
|
RNA binding protein-RNA |
X-ray (1.8 Å) |
Knott GJ, East-Seletsky A, Cofsky JC, Holton JM,
Charles E, O'Connell MR, Doudna JA |
(2017) "Guide-bound
structures of an RNA-targeting A-cleaving CRISPR-Cas13a
enzyme." Nat. Struct. Mol. Biol.,
24, 825-833. doi: 10.1038/nsmb.3466.
|
Crystal structure of lbacas13a h328a (c2c2) bound to
pre-crrna (24-nt spacer) . SNAP output
|
|
5wnp
|
ribosome |
X-ray (3.3 Å) |
Choi J, Indrisiunaite G, DeMirci H, Ieong KW, Wang J,
Petrov A, Prabhakar A, Rechavi G, Dominissini D, He C,
Ehrenberg M, Puglisi JD |
(2018) "2'-O-methylation
in mRNA disrupts tRNA decoding during translation
elongation." Nat. Struct. Mol. Biol.,
25, 208-216. doi: 10.1038/s41594-018-0030-z.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
5wnq
|
ribosome |
X-ray (3.5 Å) |
Choi J, Indrisiunaite G, DeMirci H, Ieong KW, Wang J,
Petrov A, Prabhakar A, Rechavi G, Dominissini D, He C,
Ehrenberg M, Puglisi JD |
(2018) "2'-O-methylation
in mRNA disrupts tRNA decoding during translation
elongation." Nat. Struct. Mol. Biol.,
25, 208-216. doi: 10.1038/s41594-018-0030-z.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
5wnr
|
ribosome |
X-ray (3.5 Å) |
Choi J, Indrisiunaite G, DeMirci H, Ieong KW, Wang J,
Petrov A, Prabhakar A, Rechavi G, Dominissini D, He C,
Ehrenberg M, Puglisi JD |
(2018) "2'-O-methylation
in mRNA disrupts tRNA decoding during translation
elongation." Nat. Struct. Mol. Biol.,
25, 208-216. doi: 10.1038/s41594-018-0030-z.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
5wns
|
ribosome |
X-ray (3.5 Å) |
Choi J, Indrisiunaite G, DeMirci H, Ieong KW, Wang J,
Petrov A, Prabhakar A, Rechavi G, Dominissini D, He C,
Ehrenberg M, Puglisi JD |
(2018) "2'-O-methylation
in mRNA disrupts tRNA decoding during translation
elongation." Nat. Struct. Mol. Biol.,
25, 208-216. doi: 10.1038/s41594-018-0030-z.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
5wnt
|
ribosome |
X-ray (3.3 Å) |
Choi J, Indrisiunaite G, DeMirci H, Ieong KW, Wang J,
Petrov A, Prabhakar A, Rechavi G, Dominissini D, He C,
Ehrenberg M, Puglisi JD |
(2018) "2'-O-methylation
in mRNA disrupts tRNA decoding during translation
elongation." Nat. Struct. Mol. Biol.,
25, 208-216. doi: 10.1038/s41594-018-0030-z.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
5wnu
|
ribosome |
X-ray (3.4 Å) |
Choi J, Indrisiunaite G, DeMirci H, Ieong KW, Wang J,
Petrov A, Prabhakar A, Rechavi G, Dominissini D, He C,
Ehrenberg M, Puglisi JD |
(2018) "2'-O-methylation
in mRNA disrupts tRNA decoding during translation
elongation." Nat. Struct. Mol. Biol.,
25, 208-216. doi: 10.1038/s41594-018-0030-z.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
5wnv
|
ribosome |
X-ray (3.3 Å) |
Choi J, Indrisiunaite G, DeMirci H, Ieong KW, Wang J,
Petrov A, Prabhakar A, Rechavi G, Dominissini D, He C,
Ehrenberg M, Puglisi JD |
(2018) "2'-O-methylation
in mRNA disrupts tRNA decoding during translation
elongation." Nat. Struct. Mol. Biol.,
25, 208-216. doi: 10.1038/s41594-018-0030-z.
|
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
5wqe
|
RNA binding protein |
X-ray (3.126 Å) |
Liu L, Chen P, Wang M, Li X, Wang J, Yin M, Wang
Y |
(2017) "C2c1-sgRNA
Complex Structure Reveals RNA-Guided DNA Cleavage
Mechanism." Mol. Cell,
65, 310-322. doi: 10.1016/j.molcel.2016.11.040.
|
Crystal structure of alicyclobacillus acidoterrestris
c2c1 in complex with single-guide RNA at 3.1 angstrom
resolution . SNAP
output
|
|
5ws2
|
hydrolase |
X-ray (2.398 Å) |
Zheng X, Feng N, Li D, Dong X, Li J |
(2017) "New
molecular insights into an archaeal RNase J reveal a
conserved processive exoribonucleolysis mechanism of
the RNase J family." Mol. Microbiol.,
106, 351-366. doi: 10.1111/mmi.13769.
|
Crystal structure of mpy-rnase j (mutant s247a), an
archaeal rnase j from methanolobus psychrophilus r15,
complex with RNA . SNAP
output
|
|
5wsg
|
RNA binding protein-RNA |
cryo-EM (4.0 Å) |
Yan C, Wan R, Bai R, Huang G, Shi Y |
(2017) "Structure
of a yeast step II catalytically activated
spliceosome." Science,
355, 149-155. doi: 10.1126/science.aak9979.
|
cryo-EM structure of the catalytic step ii spliceosome
(c* complex) at 4.0 angstrom resolution . SNAP output
|
|
5wt1
|
transferase-RNA |
X-ray (2.598 Å) |
Wang C, Jia Q, Zeng J, Chen R, Xie W |
(2017) "Structural
insight into the methyltransfer mechanism of the
bifunctional Trm5." Sci Adv,
3, e1700195. doi: 10.1126/sciadv.1700195.
|
Pyrococcus abyssi methyltransferase patrm5a bound by
sah and cognate trna . SNAP output
|
|
5wt3
|
transferase-RNA |
X-ray (3.204 Å) |
Wang C, Jia Q, Zeng J, Chen R, Xie W |
(2017) "Structural
insight into the methyltransfer mechanism of the
bifunctional Trm5." Sci Adv,
3, e1700195. doi: 10.1126/sciadv.1700195.
|
Pyrococcus abyssi methyltransferase patrm5a bound by
mta and cognate trna . SNAP output
|
|
5wtk
|
hydrolase-RNA |
X-ray (2.651 Å) |
Liu L, Li X, Wang J, Wang M, Chen P, Yin M, Li J,
Sheng G, Wang Y |
(2017) "Two
Distant Catalytic Sites Are Responsible for C2c2 RNase
Activities." Cell, 168,
121-134.e12. doi: 10.1016/j.cell.2016.12.031.
|
Crystal structure of rnp complex . SNAP output
|
|
5wty
|
RNA binding protein-RNA |
X-ray (2.785 Å) |
Wang B, Ye K |
(2017) "Nop9
binds the central pseudoknot region of 18S rRNA."
Nucleic Acids Res., 45,
3559-3567. doi: 10.1093/nar/gkw1323.
|
Structure of nop9 RNA complex . SNAP output
|
|
5wwe
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Wu B, Su S, Patil DP, Liu H, Gan J, Jaffrey SR, Ma
J |
(2018) "Molecular
basis for the specific and multivariant recognitions of
RNA substrates by human hnRNP A2/B1." Nat
Commun, 9, 420. doi: 10.1038/s41467-017-02770-z.
|
Crystal structure of hnrnpa2b1 in complex with RNA .
SNAP output
|
|
5wwf
|
RNA binding protein-RNA |
X-ray (2.15 Å) |
Wu B, Su S, Patil DP, Liu H, Gan J, Jaffrey SR, Ma
J |
(2018) "Molecular
basis for the specific and multivariant recognitions of
RNA substrates by human hnRNP A2/B1." Nat
Commun, 9, 420. doi: 10.1038/s41467-017-02770-z.
|
Crystal structure of hnrnpa2b1 in complex with RNA .
SNAP output
|
|
5wwg
|
RNA binding protein-RNA |
X-ray (2.03 Å) |
Wu B, Su S, Patil DP, Liu H, Gan J, Jaffrey SR, Ma
J |
(2018) "Molecular
basis for the specific and multivariant recognitions of
RNA substrates by human hnRNP A2/B1." Nat
Commun, 9, 420. doi: 10.1038/s41467-017-02770-z.
|
Crystal structure of hnrnpa2b1 in complex with
aaggacuugc . SNAP
output
|
|
5wwr
|
transferase-RNA |
X-ray (3.096 Å) |
Liu RJ, Long T, Li J, Li H, Wang ED |
(2017) "Structural
basis for substrate binding and catalytic mechanism of
a human RNA:m5C methyltransferase NSun6."
Nucleic Acids Res., 45,
6684-6697. doi: 10.1093/nar/gkx473.
|
Crystal structure of human nsun6-trna-sfg . SNAP output
|
|
5wws
|
transferase-RNA |
X-ray (3.247 Å) |
Liu RJ, Long T, Li J, Li H, Wang ED |
(2017) "Structural
basis for substrate binding and catalytic mechanism of
a human RNA:m5C methyltransferase NSun6."
Nucleic Acids Res., 45,
6684-6697. doi: 10.1093/nar/gkx473.
|
Crystal structure of human nsun6-trna-sam . SNAP output
|
|
5wwt
|
transferase-RNA |
X-ray (3.197 Å) |
Liu RJ, Long T, Li J, Li H, Wang ED |
(2017) "Structural
basis for substrate binding and catalytic mechanism of
a human RNA:m5C methyltransferase NSun6."
Nucleic Acids Res., 45,
6684-6697. doi: 10.1093/nar/gkx473.
|
Crystal structure of human nsun6-trna . SNAP output
|
|
5www
|
RNA binding protein-RNA |
X-ray (1.798 Å) |
Yang L, Wang C, Li F, Zhang J, Nayab A, Wu J, Shi Y,
Gong Q |
(2017) "The
human RNA-binding protein and E3 ligase MEX-3C binds
the MEX-3-recognition element (MRE) motif with high
affinity." J. Biol. Chem.,
292, 16221-16234. doi: 10.1074/jbc.M117.797746.
|
Crystal structure of the kh1 domain of human
RNA-binding e3 ubiquitin-protein ligase mex-3c complex
with RNA . SNAP
output
|
|
5wwx
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Yang L, Wang C, Li F, Zhang J, Nayab A, Wu J, Shi Y,
Gong Q |
(2017) "The
human RNA-binding protein and E3 ligase MEX-3C binds
the MEX-3-recognition element (MRE) motif with high
affinity." J. Biol. Chem.,
292, 16221-16234. doi: 10.1074/jbc.M117.797746.
|
Crystal structure of the kh2 domain of human
RNA-binding e3 ubiquitin-protein ligase mex-3c complex
with RNA . SNAP
output
|
|
5wyj
|
ribosome |
cryo-EM (8.7 Å) |
Sun Q, Zhu X, Qi J, An W, Lan P, Tan D, Chen R, Wang
B, Zheng S, Zhang C, Chen X, Zhang W, Chen J, Dong MQ, Ye
K |
(2017) "Molecular
architecture of the 90S small subunit
pre-ribosome." Elife, 6.
doi: 10.7554/eLife.22086.
|
cryo-EM structure of the 90s small subunit pre-ribosome
(dhr1-depleted, enp1-tap, state 1) . SNAP output
|
|
5wyk
|
ribosome |
cryo-EM (4.5 Å) |
Sun Q, Zhu X, Qi J, An W, Lan P, Tan D, Chen R, Wang
B, Zheng S, Zhang C, Chen X, Zhang W, Chen J, Dong MQ, Ye
K |
(2017) "Molecular
architecture of the 90S small subunit
pre-ribosome." Elife, 6.
doi: 10.7554/eLife.22086.
|
cryo-EM structure of the 90s small subunit pre-ribosome
(mtr4-depleted, enp1-tap) . SNAP output
|
|
5wzg
|
RNA binding protein-RNA |
X-ray (2.55 Å) |
Bao H, Wang N, Wang C, Jiang Y, Liu J, Xu L, Wu J,
Shi Y |
(2017) "Structural
basis for the specific recognition of 18S rRNA by
APUM23." Nucleic Acids Res.,
45, 12005-12014. doi: 10.1093/nar/gkx872.
|
Structure of apum23-gaauugacgg . SNAP output
|
|
5wzh
|
RNA binding protein-RNA |
X-ray (2.509 Å) |
Bao H, Wang N, Wang C, Jiang Y, Liu J, Xu L, Wu J,
Shi Y |
(2017) "Structural
basis for the specific recognition of 18S rRNA by
APUM23." Nucleic Acids Res.,
45, 12005-12014. doi: 10.1093/nar/gkx872.
|
Structure of apum23-ggaauugacgg . SNAP output
|
|
5wzi
|
RNA binding protein-RNA |
X-ray (2.75 Å) |
Bao H, Wang N, Wang C, Jiang Y, Liu J, Xu L, Wu J,
Shi Y |
(2017) "Structural
basis for the specific recognition of 18S rRNA by
APUM23." Nucleic Acids Res.,
45, 12005-12014. doi: 10.1093/nar/gkx872.
|
Structure of apum23-ggaguugacgg . SNAP output
|
|
5wzj
|
RNA binding protein-RNA |
X-ray (2.101 Å) |
Bao H, Wang N, Wang C, Jiang Y, Liu J, Xu L, Wu J,
Shi Y |
(2017) "Structural
basis for the specific recognition of 18S rRNA by
APUM23." Nucleic Acids Res.,
45, 12005-12014. doi: 10.1093/nar/gkx872.
|
Structure of apum23-ggauuugacgg . SNAP output
|
|
5wzk
|
RNA binding protein-RNA |
X-ray (2.8 Å) |
Bao H, Wang N, Wang C, Jiang Y, Liu J, Xu L, Wu J,
Shi Y |
(2017) "Structural
basis for the specific recognition of 18S rRNA by
APUM23." Nucleic Acids Res.,
45, 12005-12014. doi: 10.1093/nar/gkx872.
|
Structure of
apum23-deletion-of-insert-region-ggaauugacgg . SNAP output
|
|
5x3z
|
RNA binding protein-RNA |
NMR |
Iwaoka R, Nagata T, Tsuda K, Imai T, Okano H,
Kobayashi N, Katahira M |
(2017) "Structural
Insight into the Recognition of r(UAG) by Musashi-1
RBD2, and Construction of a Model of Musashi-1 RBD1-2
Bound to the Minimum Target RNA."
Molecules, 22. doi: 10.3390/molecules22071207.
|
Solution structure of musashi1 rbd2 in complex with RNA
. SNAP output
|
|
5x6b
|
RNA binding protein-RNA |
X-ray (2.596 Å) |
Chen M, Kato K, Kubo Y, Tanaka Y, Liu Y, Long F,
Whitman WB, Lill P, Gatsogiannis C, Raunser S, Shimizu N,
Shinoda A, Nakamura A, Tanaka I, Yao M |
(2017) "Structural
basis for tRNA-dependent cysteine biosynthesis."
Nat Commun, 8, 1521. doi:
10.1038/s41467-017-01543-y.
|
Crystal structure of sepcyse-sepcyss in complex with
trnacys from methanocaldococcus jannaschii . SNAP output
|
|
5x70
|
transferase-RNA |
X-ray (3.3 Å) |
Nakamichi Y, Higashiura A, Narita H, Hagiwara K,
Uehara-Ichiki T, Omura T, Nakagawa A |
"Crystal structure of capping enzyme from Rice dwarf
virus." |
Crystal structure of rice dwarf virus p5 in complex
with a ssrna oligomer . SNAP output
|
|
5x8p
|
ribosome |
cryo-EM (3.4 Å) |
Ahmed T, Shi J, Bhushan S |
(2017) "Unique
localization of the plastid-specific ribosomal proteins
in the chloroplast ribosome small subunit provides
mechanistic insights into the chloroplastic
translation." Nucleic Acids Res.,
45, 8581-8595. doi: 10.1093/nar/gkx499.
|
Structure of the 70s chloroplast ribosome from spinach
. SNAP output
|
|
5x8r
|
ribosome |
cryo-EM (3.7 Å) |
Ahmed T, Shi J, Bhushan S |
(2017) "Unique
localization of the plastid-specific ribosomal proteins
in the chloroplast ribosome small subunit provides
mechanistic insights into the chloroplastic
translation." Nucleic Acids Res.,
45, 8581-8595. doi: 10.1093/nar/gkx499.
|
Structure of the 30s small subunit of chloroplast
ribosome from spinach . SNAP output
|
|
5x8t
|
ribosome |
cryo-EM (3.3 Å) |
Ahmed T, Shi J, Bhushan S |
(2017) "Unique
localization of the plastid-specific ribosomal proteins
in the chloroplast ribosome small subunit provides
mechanistic insights into the chloroplastic
translation." Nucleic Acids Res.,
45, 8581-8595. doi: 10.1093/nar/gkx499.
|
Structure of the 50s large subunit of chloroplast
ribosome from spinach . SNAP output
|
|
5xbl
|
hydrolase-RNA |
X-ray (3.052 Å) |
Guo M, Wang S, Zhu Y, Wang S, Xiong Z, Yang J, Xu Z,
Huang Z |
(2017) "Structural
basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR
protein." Nature, 546,
436-439. doi: 10.1038/nature22377.
|
Structure of nuclease in complex with associated
protein . SNAP
output
|
|
5xc6
|
hydrolase-RNA |
X-ray (2.9 Å) |
Swarbrick CMD, Basavannacharya C, Chan KWK, Chan SA,
Singh D, Wei N, Phoo WW, Luo D, Lescar J, Vasudevan
SG |
(2017) "NS3
helicase from dengue virus specifically recognizes
viral RNA sequence to ensure optimal replication."
Nucleic Acids Res., 45,
12904-12920. doi: 10.1093/nar/gkx1127.
|
Dengue virus 4 ns3 helicase in complex with ssrna sla12
. SNAP output
|
|
5xj2
|
transferase-RNA |
X-ray (2.84 Å) |
Jiang Y, Li F, Wu J, Shi Y, Gong Q |
(2017) "Structural
insights into substrate selectivity of ribosomal RNA
methyltransferase RlmCD." PLoS ONE,
12, e0185226. doi: 10.1371/journal.pone.0185226.
|
Structure of sprlmcd with u747 RNA . SNAP output
|
|
5xjc
|
splicing |
cryo-EM (3.6 Å) |
Zhang X, Yan C, Hang J, Finci LI, Lei J, Shi Y |
(2017) "An
Atomic Structure of the Human Spliceosome."
Cell, 169, 918-929.e14. doi:
10.1016/j.cell.2017.04.033.
|
cryo-EM structure of the human spliceosome just prior
to exon ligation at 3.6 angstrom . SNAP output
|
|
5xlo
|
immune system-RNA |
cryo-EM (3.8 Å) |
Peng R, Xu Y, Zhu T, Li N, Qi J, Chai Y, Wu M, Zhang
X, Shi Y, Wang P, Wang J, Gao N, Gao GF |
(2017) "Alternate
binding modes of anti-CRISPR viral suppressors AcrF1/2
to Csy surveillance complex revealed by cryo-EM
structures." Cell Res.,
27, 853-864. doi: 10.1038/cr.2017.79.
|
Anti-crispr proteins acrf1-2 bound to csy surveillance
complex with a 32nt spacer crrna backbone region .
SNAP output
|
|
5xlp
|
immune system-RNA |
cryo-EM (4.2 Å) |
Peng R, Xu Y, Zhu T, Li N, Qi J, Chai Y, Wu M, Zhang
X, Shi Y, Wang P, Wang J, Gao N, Gao GF |
(2017) "Alternate
binding modes of anti-CRISPR viral suppressors AcrF1/2
to Csy surveillance complex revealed by cryo-EM
structures." Cell Res.,
27, 853-864. doi: 10.1038/cr.2017.79.
|
Anti-crispr proteins acrf1-2 bound to csy surveillance
complex with a 20nt spacer crrna backbone region .
SNAP output
|
|
5xsp
|
hydrolase |
X-ray (2.146 Å) |
Wang F, He Q, Su K, Wei T, Xu S, Gu L |
(2018) "Structural
and biochemical characterization of the catalytic
domains of GdpP reveals a unified hydrolysis mechanism
for the DHH/DHHA1 phosphodiesterase." Biochem.
J., 475, 191-205. doi: 10.1042/BCJ20170739.
|
The catalytic domain of gdpp with 5'-papa . SNAP output
|
|
5xtm
|
RNA binding protein-RNA |
X-ray (2.1 Å) |
Oshima K, Gao X, Hayashi S, Ueda T, Nakashima T,
Kimura M |
(2018) "Crystal
structures of the archaeal RNase P protein Rpp38 in
complex with RNA fragments containing a K-turn
motif." Acta Crystallogr F Struct Biol
Commun, 74, 57-64. doi: 10.1107/S2053230X17018039.
|
Crystal structure of phorpp38 bound to a k-turn in
p12.2 helix . SNAP
output
|
|
5xwp
|
RNA binding protein-RNA |
X-ray (3.086 Å) |
Liu L, Li X, Ma J, Li Z, You L, Wang J, Wang M, Zhang
X, Wang Y |
(2017) "The
Molecular Architecture for RNA-Guided RNA Cleavage by
Cas13a." Cell, 170,
714-726.e10. doi: 10.1016/j.cell.2017.06.050.
|
Crystal structure of lbucas13a-crrna-target RNA ternary
complex . SNAP
output
|
|
5xwy
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Liu L, Li X, Ma J, Li Z, You L, Wang J, Wang M, Zhang
X, Wang Y |
(2017) "The
Molecular Architecture for RNA-Guided RNA Cleavage by
Cas13a." Cell, 170,
714-726.e10. doi: 10.1016/j.cell.2017.06.050.
|
Electron cryo-microscopy structure of lbucas13a-crrna
binary complex . SNAP
output
|
|
5xxb
|
ribosome |
cryo-EM (3.17 Å) |
Li Z, Guo Q, Zheng L, Ji Y, Xie YT, Lai DH, Lun ZR,
Suo X, Gao N |
(2017) "Cryo-EM
structures of the 80S ribosomes from human parasites
Trichomonas vaginalis and Toxoplasma gondii."
Cell Res., 27, 1275-1288.
doi: 10.1038/cr.2017.104.
|
Large subunit of toxoplasma gondii ribosome . SNAP output
|
|
5xxu
|
ribosome |
cryo-EM (3.35 Å) |
Li Z, Guo Q, Zheng L, Ji Y, Xie YT, Lai DH, Lun ZR,
Suo X, Gao N |
(2017) "Cryo-EM
structures of the 80S ribosomes from human parasites
Trichomonas vaginalis and Toxoplasma gondii."
Cell Res., 27, 1275-1288.
doi: 10.1038/cr.2017.104.
|
Small subunit of toxoplasma gondii ribosome . SNAP output
|
|
5xy3
|
ribosome |
cryo-EM (3.2 Å) |
Li Z, Guo Q, Zheng L, Ji Y, Xie YT, Lai DH, Lun ZR,
Suo X, Gao N |
(2017) "Cryo-EM
structures of the 80S ribosomes from human parasites
Trichomonas vaginalis and Toxoplasma gondii."
Cell Res., 27, 1275-1288.
doi: 10.1038/cr.2017.104.
|
Large subunit of trichomonas vaginalis ribosome .
SNAP output
|
|
5xyi
|
ribosome |
cryo-EM (3.35 Å) |
Li Z, Guo Q, Zheng L, Ji Y, Xie YT, Lai DH, Lun ZR,
Suo X, Gao N |
(2017) "Cryo-EM
structures of the 80S ribosomes from human parasites
Trichomonas vaginalis and Toxoplasma gondii."
Cell Res., 27, 1275-1288.
doi: 10.1038/cr.2017.104.
|
Small subunit of trichomonas vaginalis ribosome .
SNAP output
|
|
5xym
|
ribosome |
cryo-EM (3.08 Å) |
Li Z, Ge X, Zhang Y, Zheng L, Sanyal S, Gao N |
(2018) "Cryo-EM
structure of Mycobacterium smegmatis ribosome reveals
two unidentified ribosomal proteins close to the
functional centers." Protein Cell,
9, 384-388. doi: 10.1007/s13238-017-0456-9.
|
Large subunit of mycobacterium smegmatis . SNAP output
|
|
5xyu
|
ribosome |
cryo-EM (3.45 Å) |
Li Z, Ge X, Zhang Y, Zheng L, Sanyal S, Gao N |
(2018) "Cryo-EM
structure of Mycobacterium smegmatis ribosome reveals
two unidentified ribosomal proteins close to the
functional centers." Protein Cell,
9, 384-388. doi: 10.1007/s13238-017-0456-9.
|
Small subunit of mycobacterium smegmatis ribosome .
SNAP output
|
|
5y58
|
RNA binding protein |
X-ray (2.8 Å) |
Chen H, Xue J, Churikov D, Hass EP, Shi S, Lemon LD,
Luciano P, Bertuch AA, Zappulla DC, Geli V, Wu J, Lei
M |
(2018) "Structural
Insights into Yeast Telomerase Recruitment to
Telomeres." Cell, 172,
331-343.e13. doi: 10.1016/j.cell.2017.12.008.
|
Crystal structure of ku70-80 and tlc1 . SNAP output
|
|
5y6z
|
transferase-RNA |
X-ray (2.5 Å) |
Bi P, Shu B, Gong P |
(2017) "Crystal
structure of the coxsackievirus A16 RNA-dependent RNA
polymerase elongation complex reveals novel features in
motif A dynamics." Virol Sin,
32, 548-552. doi: 10.1007/s12250-017-4066-8.
|
Crystal structure of the coxsackievirus a16 polymerase
elongation complex . SNAP output
|
|
5y7m
|
RNA binding protein |
X-ray (3.1 Å) |
Oshima K, Gao X, Hayashi S, Ueda T, Nakashima T,
Kimura M |
(2018) "Crystal
structures of the archaeal RNase P protein Rpp38 in
complex with RNA fragments containing a K-turn
motif." Acta Crystallogr F Struct Biol
Commun, 74, 57-64. doi: 10.1107/S2053230X17018039.
|
Crystal structure of phorpp38 bound to a k-turn in
p12.1 helix . SNAP
output
|
|
5y88
|
splicing |
cryo-EM (3.46 Å) |
Wan R, Yan C, Bai R, Lei J, Shi Y |
(2017) "Structure
of an Intron Lariat Spliceosome from Saccharomyces
cerevisiae." Cell(Cambridge,Mass.),
171, 120-132. doi: 10.1016/j.cell.2017.08.029.
|
cryo-EM structure of the intron-lariat spliceosome
ready for disassembly from s.cerevisiae at 3.5 angstrom
. SNAP output
|
|
5ydt
|
ribosome |
cryo-EM (4.5 Å) |
Hu J, Zhu X, Ye K |
(2017) "Structure
and RNA recognition of ribosome assembly factor
Utp30." RNA, 23,
1936-1945. doi: 10.1261/rna.062695.117.
|
Remodeled utp30 in 90s pre-ribosome (mtr4-depleted,
enp1-tap) . SNAP
output
|
|
5yki
|
RNA binding protein-RNA |
X-ray (2.25 Å) |
Zhao YY, Mao MW, Zhang WJ, Wang J, Li HT, Yang Y,
Wang Z, Wu JW |
(2018) "Expanding
RNA binding specificity and affinity of engineered PUF
domains." Nucleic Acids Res.,
46, 4771-4782. doi: 10.1093/nar/gky134.
|
Crystal structure of the engineered nine-repeat puf
domain in complex with cognate 9nt-RNA . SNAP output
|
|
5ylz
|
splicing |
cryo-EM (3.6 Å) |
Bai R, Yan C, Wan R, Lei J, Shi Y |
(2017) "Structure
of the Post-catalytic Spliceosome from Saccharomyces
cerevisiae." Cell, 171,
1589-1598.e8. doi: 10.1016/j.cell.2017.10.038.
|
cryo-EM structure of the post-catalytic spliceosome
from saccharomyces cerevisiae at 3.6 angstrom .
SNAP output
|
|
5yts
|
RNA binding protein-RNA |
X-ray (1.77 Å) |
Yang XJ, Zhu H, Mu SR, Wei WJ, Yuan X, Wang M, Liu Y,
Hui J, Huang Y |
(2019) "Crystal
structure of a Y-box binding protein 1 (YB-1)-RNA
complex reveals key features and residues interacting
with RNA." J.Biol.Chem.,
294, 10998-11010. doi: 10.1074/jbc.RA119.007545.
|
Crystal structure of yb1 cold-shock domain in complex
with ucuucu . SNAP
output
|
|
5ytt
|
RNA binding protein-RNA |
X-ray (1.6 Å) |
Yang XJ, Zhu H, Mu SR, Wei WJ, Yuan X, Wang M, Liu Y,
Hui J, Huang Y |
(2019) "Crystal
structure of a Y-box binding protein 1 (YB-1)-RNA
complex reveals key features and residues interacting
with RNA." J.Biol.Chem.,
294, 10998-11010. doi: 10.1074/jbc.RA119.007545.
|
Crystal structure of yb1 cold-shock domain in complex
with ucaugu . SNAP
output
|
|
5ytv
|
RNA binding protein-RNA |
X-ray (1.7 Å) |
Yang XJ, Zhu H, Mu SR, Wei WJ, Yuan X, Wang M, Liu Y,
Hui J, Huang Y |
(2019) "Crystal
structure of a Y-box binding protein 1 (YB-1)-RNA
complex reveals key features and residues interacting
with RNA." J.Biol.Chem.,
294, 10998-11010. doi: 10.1074/jbc.RA119.007545.
|
Crystal structure of yb1 cold-shock domain in complex
with ucaucu . SNAP
output
|
|
5ytx
|
RNA binding protein-RNA |
X-ray (1.551 Å) |
Yang XJ, Zhu H, Mu SR, Wei WJ, Yuan X, Wang M, Liu Y,
Hui J, Huang Y |
(2019) "Crystal
structure of a Y-box binding protein 1 (YB-1)-RNA
complex reveals key features and residues interacting
with RNA." J.Biol.Chem.,
294, 10998-11010. doi: 10.1074/jbc.RA119.007545.
|
Crystal structure of yb1 cold-shock domain in complex
with ucaacu . SNAP
output
|
|
5yyn
|
ligase-RNA |
X-ray (3.0 Å) |
Zhou M, Ye S, Stephen P, Zhang RG, Wang ED, Giege R,
Lin SX |
"Crystal Structures Of E.Coli Arginyl-Trna Synthetase
(Argrs) In Complex With Substrates." |
Crystal structures of e.coli arginyl-trna synthetase
(argrs) in complex with substrate trna(arg) . SNAP output
|
|
5yzg
|
splicing |
cryo-EM (4.1 Å) |
Zhan X, Yan C, Zhang X, Lei J, Shi Y |
(2018) "Structure
of a human catalytic step I spliceosome."
Science, 359, 537-545. doi:
10.1126/science.aar6401.
|
The cryo-EM structure of human catalytic step i
spliceosome (c complex) at 4.1 angstrom resolution .
SNAP output
|
|
5z3g
|
ribosome |
cryo-EM (3.65 Å) |
Zhou D, Zhu X, Zheng S, Tan D, Dong MQ, Ye K |
(2019) "Cryo-EM
structure of an early precursor of large ribosomal
subunit reveals a half-assembled intermediate."
Protein Cell, 10, 120-130.
doi: 10.1007/s13238-018-0526-7.
|
cryo-EM structure of a nucleolar pre-60s ribosome
(rpf1-tap) . SNAP
output
|
|
5z4a
|
transferase-RNA |
X-ray (1.637 Å) |
Cheng L, Li F, Jiang Y, Yu H, Xie C, Shi Y, Gong
Q |
(2019) "Structural
insights into a unique preference for 3' terminal
guanine of mirtron in Drosophila TUTase tailor."
Nucleic Acids Res., 47,
495-508. doi: 10.1093/nar/gky1116.
|
Structure of tailor in complex with agu RNA . SNAP output
|
|
5z4d
|
transferase-RNA |
X-ray (1.803 Å) |
Cheng L, Li F, Jiang Y, Yu H, Xie C, Shi Y, Gong
Q |
(2019) "Structural
insights into a unique preference for 3' terminal
guanine of mirtron in Drosophila TUTase tailor."
Nucleic Acids Res., 47,
495-508. doi: 10.1093/nar/gky1116.
|
Structure of tailor in complex with aguu RNA . SNAP output
|
|
5z4j
|
transferase-RNA |
X-ray (1.82 Å) |
Cheng L, Li F, Jiang Y, Yu H, Xie C, Shi Y, Gong
Q |
(2019) "Structural
insights into a unique preference for 3' terminal
guanine of mirtron in Drosophila TUTase tailor."
Nucleic Acids Res., 47,
495-508. doi: 10.1093/nar/gky1116.
|
Structure of tailor in complex with u4 RNA . SNAP output
|
|
5z56
|
splicing |
cryo-EM (5.1 Å) |
Zhang X, Yan C, Zhan X, Li L, Lei J, Shi Y |
(2018) "Structure
of the human activated spliceosome in three
conformational states." Cell Res.,
28, 307-322. doi: 10.1038/cr.2018.14.
|
cryo-EM structure of a human activated spliceosome
(mature bact) at 5.1 angstrom. . SNAP output
|
|
5z57
|
splicing |
cryo-EM (6.5 Å) |
Zhang X, Yan C, Zhan X, Li L, Lei J, Shi Y |
(2018) "Structure
of the human activated spliceosome in three
conformational states." Cell Res.,
28, 307-322. doi: 10.1038/cr.2018.14.
|
cryo-EM structure of the human activated spliceosome
(late bact) at 6.5 angstrom . SNAP output
|
|
5z58
|
splicing |
cryo-EM (4.9 Å) |
Zhang X, Yan C, Zhan X, Li L, Lei J, Shi Y |
(2018) "Structure
of the human activated spliceosome in three
conformational states." Cell Res.,
28, 307-322. doi: 10.1038/cr.2018.14.
|
cryo-EM structure of a human activated spliceosome
(early bact) at 4.9 angstrom. . SNAP output
|
|
5z9w
|
viral protein |
cryo-EM (3.6 Å) |
Sugita Y, Matsunami H, Kawaoka Y, Noda T, Wolf M |
(2018) "Cryo-EM
structure of the Ebola virus nucleoprotein-RNA complex
at 3.6 angstrom resolution." Nature,
563, 137-140. doi: 10.1038/s41586-018-0630-0.
|
Ebola virus nucleoprotein-RNA complex . SNAP output
|
|
5z9x
|
plant protein-RNA |
X-ray (2.8 Å) |
Chen J, Liu L, You C, Gu J, Ruan W, Zhang L, Gan J,
Cao C, Huang Y, Chen X, Ma J |
(2018) "Structural
and biochemical insights into small RNA 3' end trimming
by Arabidopsis SDN1." Nat Commun,
9, 3585. doi: 10.1038/s41467-018-05942-7.
|
Arabidopsis small RNA degrading nuclease 1 in complex
with an RNA substrate . SNAP output
|
|
5zal
|
hydrolase-protein binding-RNA |
cryo-EM (4.7 Å) |
Liu Z, Wang J, Cheng H, Ke X, Sun L, Zhang QC, Wang
HW |
(2018) "Cryo-EM
Structure of Human Dicer and Its Complexes with a
Pre-miRNA Substrate." Cell,
173, 1191-1203.e12. doi: 10.1016/j.cell.2018.03.080.
|
cryo-EM structure of human dicer and its complexes with
a pre-mirna substrate . SNAP output
|
|
5zam
|
hydrolase-protein binding-RNA |
cryo-EM (5.7 Å) |
Liu Z, Wang J, Cheng H, Ke X, Sun L, Zhang QC, Wang
HW |
(2018) "Cryo-EM
Structure of Human Dicer and Its Complexes with a
Pre-miRNA Substrate." Cell,
173, 1191-1203.e12. doi: 10.1016/j.cell.2018.03.080.
|
cryo-EM structure of human dicer and its complexes with
a pre-mirna substrate . SNAP output
|
|
5zc9
|
translation-RNA |
X-ray (2.0 Å) |
Iwasaki S, Iwasaki W, Takahashi M, Sakamoto A,
Watanabe C, Shichino Y, Floor SN, Fujiwara K, Mito M,
Dodo K, Sodeoka M, Imataka H, Honma T, Fukuzawa K, Ito T,
Ingolia NT |
(2019) "The
Translation Inhibitor Rocaglamide Targets a Bimolecular
Cavity between eIF4A and Polypurine RNA." Mol.
Cell, 73, 738. doi: 10.1016/j.molcel.2018.11.026.
|
Crystal structure of the human eif4a1-atp
analog-roca-polypurine RNA complex . SNAP output
|
|
5zeb
|
ribosome |
cryo-EM (3.4 Å) |
Mishra S, Ahmed T, Tyagi A, Shi J, Bhushan S |
(2018) "Structures
of Mycobacterium smegmatis 70S ribosomes in complex
with HPF, tmRNA, and P-tRNA." Sci Rep,
8, 13587. doi: 10.1038/s41598-018-31850-3.
|
M. smegmatis p-p state 70s ribosome structure .
SNAP output
|
|
5zep
|
ribosome |
cryo-EM (3.4 Å) |
Mishra S, Ahmed T, Tyagi A, Shi J, Bhushan S |
(2018) "Structures
of Mycobacterium smegmatis 70S ribosomes in complex
with HPF, tmRNA, and P-tRNA." Sci Rep,
8, 13587. doi: 10.1038/s41598-018-31850-3.
|
M. smegmatis hibernating state 70s ribosome structure .
SNAP output
|
|
5zet
|
ribosome |
cryo-EM (3.2 Å) |
Mishra S, Ahmed T, Tyagi A, Shi J, Bhushan S |
(2018) "Structures
of Mycobacterium smegmatis 70S ribosomes in complex
with HPF, tmRNA, and P-tRNA." Sci Rep,
8, 13587. doi: 10.1038/s41598-018-31850-3.
|
M. smegmatis p-p state 50s ribosomal subunit . SNAP output
|
|
5zeu
|
ribosome |
cryo-EM (3.7 Å) |
Mishra S, Ahmed T, Tyagi A, Shi J, Bhushan S |
(2018) "Structures
of Mycobacterium smegmatis 70S ribosomes in complex
with HPF, tmRNA, and P-tRNA." Sci Rep,
8, 13587. doi: 10.1038/s41598-018-31850-3.
|
M. smegmatis p-p state 30s ribosomal subunit . SNAP output
|
|
5zey
|
RNA binding protein-RNA |
cryo-EM (12.5 Å) |
Mishra S, Ahmed T, Tyagi A, Shi J, Bhushan S |
(2018) "Structures
of Mycobacterium smegmatis 70S ribosomes in complex
with HPF, tmRNA, and P-tRNA." Sci Rep,
8, 13587. doi: 10.1038/s41598-018-31850-3.
|
M. smegmatis trans-translation state 70s ribosome .
SNAP output
|
|
5zlu
|
ribosome |
cryo-EM (3.6 Å) |
Su W, Kumar V, Ding Y, Ero R, Serra A, Lee BST, Wong
ASW, Shi J, Sze SK, Yang L, Gao YG |
(2018) "Ribosome
protection by antibiotic resistance ATP-binding
cassette protein." Proc. Natl. Acad. Sci.
U.S.A., 115, 5157-5162. doi:
10.1073/pnas.1803313115.
|
Ribosome structure bound to abc-f protein. . SNAP output
|
|
5zq0
|
transferase-RNA |
X-ray (2.0 Å) |
Jiang Y, Yu H, Li F, Cheng L, Zhu L, Shi Y, Gong
Q |
(2018) "Unveiling
the structural features that determine the dual
methyltransferase activities of Streptococcus
pneumoniae RlmCD." PLoS Pathog.,
14, e1007379. doi: 10.1371/journal.ppat.1007379.
|
Crystal structure of sprlmcd with u747loop RNA .
SNAP output
|
|
5zq1
|
transferase-RNA |
X-ray (3.1 Å) |
Jiang Y, Yu H, Li F, Cheng L, Zhu L, Shi Y, Gong
Q |
(2018) "Unveiling
the structural features that determine the dual
methyltransferase activities of Streptococcus
pneumoniae RlmCD." PLoS Pathog.,
14, e1007379. doi: 10.1371/journal.ppat.1007379.
|
Crystal structure of sprlmcd with u1939loop RNA at 3.10
angstrom . SNAP
output
|
|
5zq8
|
transferase-RNA |
X-ray (2.18 Å) |
Jiang Y, Yu H, Li F, Cheng L, Zhu L, Shi Y, Gong
Q |
(2018) "Unveiling
the structural features that determine the dual
methyltransferase activities of Streptococcus
pneumoniae RlmCD." PLoS Pathog.,
14, e1007379. doi: 10.1371/journal.ppat.1007379.
|
Crystal structure of sprlmcd with u747 stemloop RNA .
SNAP output
|
|
5zsa
|
immune system |
X-ray (2.5 Å) |
Zhang Z, Ohto U, Shibata T, Taoka M, Yamauchi Y, Sato
R, Shukla NM, David SA, Isobe T, Miyake K, Shimizu T |
(2018) "Structural
Analyses of Toll-like Receptor 7 Reveal Detailed RNA
Sequence Specificity and Recognition Mechanism of
Agonistic Ligands." Cell Rep,
25, 3371-3381.e5. doi: 10.1016/j.celrep.2018.11.081.
|
Crystal structure of monkey tlr7 in complex with imdq
and uuuuuu . SNAP
output
|
|
5zsb
|
immune system |
X-ray (2.7 Å) |
Zhang Z, Ohto U, Shibata T, Taoka M, Yamauchi Y, Sato
R, Shukla NM, David SA, Isobe T, Miyake K, Shimizu T |
(2018) "Structural
Analyses of Toll-like Receptor 7 Reveal Detailed RNA
Sequence Specificity and Recognition Mechanism of
Agonistic Ligands." Cell Rep,
25, 3371-3381.e5. doi: 10.1016/j.celrep.2018.11.081.
|
Crystal structure of monkey tlr7 in complex with imdq
and aauuaa . SNAP
output
|
|
5zsc
|
immune system |
X-ray (2.2 Å) |
Zhang Z, Ohto U, Shibata T, Taoka M, Yamauchi Y, Sato
R, Shukla NM, David SA, Isobe T, Miyake K, Shimizu T |
(2018) "Structural
Analyses of Toll-like Receptor 7 Reveal Detailed RNA
Sequence Specificity and Recognition Mechanism of
Agonistic Ligands." Cell Rep,
25, 3371-3381.e5. doi: 10.1016/j.celrep.2018.11.081.
|
Crystal structure of monkey tlr7 in complex with imdq
and ccuucc . SNAP
output
|
|
5zsd
|
immune system |
X-ray (2.603 Å) |
Zhang Z, Ohto U, Shibata T, Taoka M, Yamauchi Y, Sato
R, Shukla NM, David SA, Isobe T, Miyake K, Shimizu T |
(2018) "Structural
Analyses of Toll-like Receptor 7 Reveal Detailed RNA
Sequence Specificity and Recognition Mechanism of
Agonistic Ligands." Cell Rep,
25, 3371-3381.e5. doi: 10.1016/j.celrep.2018.11.081.
|
Crystal structure of monkey tlr7 in complex with imdq
and gguugg . SNAP
output
|
|
5zse
|
immune system |
X-ray (2.201 Å) |
Zhang Z, Ohto U, Shibata T, Taoka M, Yamauchi Y, Sato
R, Shukla NM, David SA, Isobe T, Miyake K, Shimizu T |
(2018) "Structural
Analyses of Toll-like Receptor 7 Reveal Detailed RNA
Sequence Specificity and Recognition Mechanism of
Agonistic Ligands." Cell Rep,
25, 3371-3381.e5. doi: 10.1016/j.celrep.2018.11.081.
|
Crystal structure of monkey tlr7 in complex with imdq
and gguccc . SNAP
output
|
|
5zsl
|
immune system |
X-ray (2.3 Å) |
Zhang Z, Ohto U, Shibata T, Taoka M, Yamauchi Y, Sato
R, Shukla NM, David SA, Isobe T, Miyake K, Shimizu T |
(2018) "Structural
Analyses of Toll-like Receptor 7 Reveal Detailed RNA
Sequence Specificity and Recognition Mechanism of
Agonistic Ligands." Cell Rep,
25, 3371-3381.e5. doi: 10.1016/j.celrep.2018.11.081.
|
Crystal structure of monkey tlr7 in complex with gguugg
. SNAP output
|
|
5zsm
|
immune system |
X-ray (2.5 Å) |
Zhang Z, Ohto U, Shibata T, Taoka M, Yamauchi Y, Sato
R, Shukla NM, David SA, Isobe T, Miyake K, Shimizu T |
(2018) "Structural
Analyses of Toll-like Receptor 7 Reveal Detailed RNA
Sequence Specificity and Recognition Mechanism of
Agonistic Ligands." Cell Rep,
25, 3371-3381.e5. doi: 10.1016/j.celrep.2018.11.081.
|
Crystal structure of monkey tlr7 in complex with gguccc
. SNAP output
|
|
5zsn
|
immune system |
X-ray (2.4 Å) |
Zhang Z, Ohto U, Shibata T, Taoka M, Yamauchi Y, Sato
R, Shukla NM, David SA, Isobe T, Miyake K, Shimizu T |
(2018) "Structural
Analyses of Toll-like Receptor 7 Reveal Detailed RNA
Sequence Specificity and Recognition Mechanism of
Agonistic Ligands." Cell Rep,
25, 3371-3381.e5. doi: 10.1016/j.celrep.2018.11.081.
|
Crystal structure of monkey tlr7 in complex with aauuaa
. SNAP output
|
|
5zth
|
transferase-RNA |
X-ray (3.24 Å) |
Jiang Y, Yu H, Li F, Cheng L, Zhu L, Shi Y, Gong
Q |
(2018) "Unveiling
the structural features that determine the dual
methyltransferase activities of Streptococcus
pneumoniae RlmCD." PLoS Pathog.,
14, e1007379. doi: 10.1371/journal.ppat.1007379.
|
Crystal structure of sprlmcd with u1939loop RNA at 3.24
angstrom . SNAP
output
|
|
5ztm
|
hydrolase-RNA |
X-ray (2.899 Å) |
Lv M, Yao Y, Li F, Xu L, Yang L, Gong Q, Xu YZ, Shi
Y, Fan YJ, Tang Y |
(2019) "Structural
insights reveal the specific recognition of roX RNA by
the dsRNA-binding domains of the RNA helicase MLE and
its indispensable role in dosage compensation in
Drosophila." Nucleic Acids Res.,
47, 3142-3157. doi: 10.1093/nar/gky1308.
|
Crystal structure of mle dsrbds in complex with rox2
(r2h1) . SNAP output
|
|
5zuu
|
RNA binding protein-RNA |
X-ray (1.95 Å) |
Hou Y, Sun J, Wu B, Gao Y, Nie H, Nie Z, Quan S, Wang
Y, Cao X, Li S |
(2021) "CPSF30-L-mediated recognition of mRNA m6A
modification controls alternative polyadenylation of
nitrate signaling-related gene transcripts in
Arabidopsis." Mol Plant. doi: 10.1016/j.molp.2021.01.013.
|
Crystal structure of atcpsf30 yth domain in complex
with 10mer m6a-modified RNA . SNAP output
|
|
5zw4
|
RNA binding protein-RNA |
X-ray (1.7 Å) |
Ryu H, Grove TL, Almo SC, Kim J |
(2018) "Identification
of a novel tRNA wobble uridine modifying activity in
the biosynthesis of 5-methoxyuridine." Nucleic
Acids Res., 46, 9160-9169. doi:
10.1093/nar/gky592.
|
Crystal structure of trna bound trmr . SNAP output
|
|
5zwm
|
splicing |
cryo-EM (3.4 Å) |
Bai R, Wan R, Yan C, Lei J, Shi Y |
(2018) "Structures
of the fully assembledSaccharomyces
cerevisiaespliceosome before activation."
Science, 360, 1423-1429. doi:
10.1126/science.aau0325.
|
cryo-EM structure of the yeast pre-b complex at an
average resolution of 3.4~4.6 angstrom (tri-snrnp and
u2 snrnp part) . SNAP
output
|
|
5zwn
|
splicing |
cryo-EM (3.4 Å) |
Bai R, Wan R, Yan C, Lei J, Shi Y |
(2018) "Structures
of the fully assembledSaccharomyces
cerevisiaespliceosome before activation."
Science, 360, 1423-1429. doi:
10.1126/science.aau0325.
|
cryo-EM structure of the yeast pre-b complex at an
average resolution of 3.3 angstrom (part ii: u1 snrnp
region) . SNAP
output
|
|
5zwo
|
splicing |
cryo-EM (3.9 Å) |
Bai R, Wan R, Yan C, Lei J, Shi Y |
(2018) "Structures
of the fully assembledSaccharomyces
cerevisiaespliceosome before activation."
Science, 360, 1423-1429. doi:
10.1126/science.aau0325.
|
cryo-EM structure of the yeast b complex at average
resolution of 3.9 angstrom . SNAP output
|
|
6a4e
|
hydrolase |
X-ray (2.45 Å) |
Lee CW, Park SH, Jeong CS, Cha SS, Park H, Lee
JH |
(2019) "Structural
basis of small RNA hydrolysis by oligoribonuclease
(CpsORN) from Colwellia psychrerythraea strain
34H." Sci Rep, 9, 2649.
doi: 10.1038/s41598-019-39641-0.
|
Two linked uridine bound oligoribonuclease (orn) from
colwellia psychrerythraea strain 34h . SNAP output
|
|
6a6j
|
RNA binding protein-RNA |
X-ray (2.255 Å) |
Yang Y, Wang L, Han X, Yang WL, Zhang M, Ma HL, Sun
BF, Li A, Xia J, Chen J, Heng J, Wu B, Chen YS, Xu JW,
Yang X, Yao H, Sun J, Lyu C, Wang HL, Huang Y, Sun YP,
Zhao YL, Meng A, Ma J, Liu F, Yang YG |
(2019) "RNA
5-Methylcytosine Facilitates the Maternal-to-Zygotic
Transition by Preventing Maternal mRNA Decay."
Mol.Cell, 75, 1188-1202.e11.
doi: 10.1016/j.molcel.2019.06.033.
|
Crystal structure of zebra fish y-box protein1 (yb-1)
cold-shock domain in complex with 6mer m5c RNA .
SNAP output
|
|
6a6l
|
RNA binding protein-RNA |
X-ray (1.78 Å) |
Huang Y |
"Crystal structure of the cold shock domain of YB-1
in complex with m5C RNA." |
Crystal structure of the cold shock domain of yb-1 in
complex with m5c RNA . SNAP output
|
|
6aax
|
transferase-RNA |
X-ray (2.994 Å) |
Liu X, Shen S, Wu P, Li F, Liu X, Wang C, Gong Q, Wu
J, Yao X, Zhang H, Shi Y |
(2019) "Structural
insights into dimethylation of 12S rRNA by TFB1M:
indispensable role in translation of mitochondrial
genes and mitochondrial function." Nucleic
Acids Res., 47, 7648-7665. doi:
10.1093/nar/gkz505.
|
Crystal structure of tfb1m and h45 with sam in homo
sapiens . SNAP
output
|
|
6aay
|
RNA binding protein-RNA |
X-ray (2.79 Å) |
Zhang B, Ye WW, Ye YM, Zhou H, Saeed AFUH, Chen J,
Lin JY, Perculija V, Chen Q, Chen CJ, Chang MX, Choudhary
MI, Ouyang SY |
(2018) "Structural
insights into Cas13b-guided CRISPR RNA maturation and
recognition." Cell Res.,
28, 1198-1201. doi: 10.1038/s41422-018-0109-4.
|
The cas13b binary complex . SNAP output
|
|
6agb
|
hydrolase-RNA |
cryo-EM (3.48 Å) |
Lan P, Tan M, Zhang Y, Niu S, Chen J, Shi S, Qiu S,
Wang X, Peng X, Cai G, Cheng H, Wu J, Li G, Lei M |
(2018) "Structural
insight into precursor tRNA processing by yeast
ribonuclease P." Science,
362. doi: 10.1126/science.aat6678.
|
cryo-EM structure of yeast ribonuclease p . SNAP output
|
|
6ah0
|
splicing |
cryo-EM (5.7 Å) |
Zhan X, Yan C, Zhang X, Lei J, Shi Y |
(2018) "Structures
of the human pre-catalytic spliceosome and its
precursor spliceosome." Cell Res.,
28, 1129-1140. doi: 10.1038/s41422-018-0094-7.
|
The cryo-EM structure of the precusor of human
pre-catalytic spliceosome (pre-b complex) . SNAP output
|
|
6ah3
|
hydrolase-RNA |
cryo-EM (3.48 Å) |
Lan P, Tan M, Zhang Y, Niu S, Chen J, Shi S, Qiu S,
Wang X, Peng X, Cai G, Cheng H, Wu J, Li G, Lei M |
(2018) "Structural
insight into precursor tRNA processing by yeast
ribonuclease P." Science,
362. doi: 10.1126/science.aat6678.
|
cryo-EM structure of yeast ribonuclease p with pre-trna
substrate . SNAP
output
|
|
6ahd
|
splicing |
cryo-EM (3.8 Å) |
Zhan X, Yan C, Zhang X, Lei J, Shi Y |
(2018) "Structures
of the human pre-catalytic spliceosome and its
precursor spliceosome." Cell Res.,
28, 1129-1140. doi: 10.1038/s41422-018-0094-7.
|
The cryo-EM structure of human pre-catalytic
spliceosome (b complex) at 3.8 angstrom resolution .
SNAP output
|
|
6ahr
|
hydrolase-RNA |
cryo-EM (3.92 Å) |
Wu J, Niu S, Tan M, Huang C, Li M, Song Y, Wang Q,
Chen J, Shi S, Lan P, Lei M |
(2018) "Cryo-EM
Structure of the Human Ribonuclease P Holoenzyme."
Cell, 175, 1393-1404.e11.
doi: 10.1016/j.cell.2018.10.003.
|
cryo-EM structure of human ribonuclease p . SNAP output
|
|
6ahu
|
hydrolase-RNA |
cryo-EM (3.66 Å) |
Wu J, Niu S, Tan M, Huang C, Li M, Song Y, Wang Q,
Chen J, Shi S, Lan P, Lei M |
(2018) "Cryo-EM
Structure of the Human Ribonuclease P Holoenzyme."
Cell, 175, 1393-1404.e11.
doi: 10.1016/j.cell.2018.10.003.
|
cryo-EM structure of human ribonuclease p with mature
trna . SNAP output
|
|
6ajk
|
transferase-RNA |
X-ray (3.001 Å) |
Liu X, Shen S, Wu P, Li F, Liu X, Wang C, Gong Q, Wu
J, Yao X, Zhang H, Shi Y |
(2019) "Structural
insights into dimethylation of 12S rRNA by TFB1M:
indispensable role in translation of mitochondrial
genes and mitochondrial function." Nucleic
Acids Res., 47, 7648-7665. doi:
10.1093/nar/gkz505.
|
Crystal structure of tfb1m and h45 in homo sapiens .
SNAP output
|
|
6aso
|
splicing |
X-ray (2.71 Å) |
Montemayor EJ, Didychuk AL, Yake AD, Sidhu GK, Brow
DA, Butcher SE |
(2018) "Architecture
of the U6 snRNP reveals specific recognition of 3'-end
processed U6 snRNA." Nat Commun,
9, 1749. doi: 10.1038/s41467-018-04145-4.
|
Structure of yeast u6 snrnp with 3'-phosphate
terminated u6 RNA . SNAP
output
|
|
6awb
|
ribosome |
cryo-EM (6.7 Å) |
Demo G, Rasouly A, Vasilyev N, Svetlov V, Loveland
AB, Diaz-Avalos R, Grigorieff N, Nudler E, Korostelev
AA |
(2017) "Structure
of RNA polymerase bound to ribosomal 30S subunit."
Elife, 6. doi: 10.7554/eLife.28560.
|
Structure of 30s ribosomal subunit and RNA polymerase
complex in non-rotated state . SNAP output
|
|
6awc
|
ribosome |
cryo-EM (7.9 Å) |
Demo G, Rasouly A, Vasilyev N, Svetlov V, Loveland
AB, Diaz-Avalos R, Grigorieff N, Nudler E, Korostelev
AA |
(2017) "Structure
of RNA polymerase bound to ribosomal 30S subunit."
Elife, 6. doi: 10.7554/eLife.28560.
|
Structure of 30s ribosomal subunit and RNA polymerase
complex in rotated state . SNAP output
|
|
6awd
|
ribosome |
cryo-EM (8.1 Å) |
Demo G, Rasouly A, Vasilyev N, Svetlov V, Loveland
AB, Diaz-Avalos R, Grigorieff N, Nudler E, Korostelev
AA |
(2017) "Structure
of RNA polymerase bound to ribosomal 30S subunit."
Elife, 6. doi: 10.7554/eLife.28560.
|
Structure of 30s (s1 depleted) ribosomal subunit and
RNA polymerase complex . SNAP output
|
|
6az1
|
ribosome-antibiotic |
cryo-EM (2.7 Å) |
Shalev-Benami M, Zhang Y, Rozenberg H, Nobe Y, Taoka
M, Matzov D, Zimmerman E, Bashan A, Isobe T, Jaffe CL,
Yonath A, Skiniotis G |
(2017) "Atomic
resolution snapshot of Leishmania ribosome inhibition
by the aminoglycoside paromomycin." Nat
Commun, 8, 1589. doi: 10.1038/s41467-017-01664-4.
|
cryo-EM structure of the small subunit of leishmania
ribosome bound to paromomycin . SNAP output
|
|
6az3
|
ribosome-antibiotic |
cryo-EM (2.5 Å) |
Shalev-Benami M, Zhang Y, Rozenberg H, Nobe Y, Taoka
M, Matzov D, Zimmerman E, Bashan A, Isobe T, Jaffe CL,
Yonath A, Skiniotis G |
(2017) "Atomic
resolution snapshot of Leishmania ribosome inhibition
by the aminoglycoside paromomycin." Nat
Commun, 8, 1589. doi: 10.1038/s41467-017-01664-4.
|
cryo-EM structure of of the large subunit of leishmania
ribosome bound to paromomycin . SNAP output
|
|
6b0b
|
hydrolase-RNA |
X-ray (3.28 Å) |
Shaban NM, Shi K, Lauer KV, Carpenter MA, Richards
CM, Salamango D, Wang J, Lopresti MW, Banerjee S,
Levin-Klein R, Brown WL, Aihara H, Harris RS |
(2018) "The
Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is
Regulated by an RNA-Mediated Dimerization
Mechanism." Mol. Cell,
69, 75-86.e9. doi: 10.1016/j.molcel.2017.12.010.
|
Crystal structure of human apobec3h . SNAP output
|
|
6b14
|
immune system-RNA |
X-ray (1.64 Å) |
Koirala D, Shelke SA, Dupont M, Ruiz S, DasGupta S,
Bailey LJ, Benner SA, Piccirilli JA |
(2018) "Affinity
maturation of a portable Fab-RNA module for
chaperone-assisted RNA crystallography."
Nucleic Acids Res., 46,
2624-2635. doi: 10.1093/nar/gkx1292.
|
Crystal structure of spinach RNA aptamer in complex
with fab bl3-6s97n . SNAP output
|
|
6b3k
|
immune system-RNA |
X-ray (2.09 Å) |
Koirala D, Shelke SA, Dupont M, Ruiz S, DasGupta S,
Bailey LJ, Benner SA, Piccirilli JA |
(2018) "Affinity
maturation of a portable Fab-RNA module for
chaperone-assisted RNA crystallography."
Nucleic Acids Res., 46,
2624-2635. doi: 10.1093/nar/gkx1292.
|
Crystal structure of mutant spinach RNA aptamer in
complex with fab bl3-6 . SNAP output
|
|
6b45
|
immune system - RNA |
cryo-EM (3.5 Å) |
Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P,
Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ,
Subramaniam S |
(2017) "Cryo-EM
Structures Reveal Mechanism and Inhibition of DNA
Targeting by a CRISPR-Cas Surveillance Complex."
Cell, 171, 414-426.e12. doi:
10.1016/j.cell.2017.09.006.
|
cryo-EM structure of type i-f crispr crrna-guided csy
surveillance complex . SNAP output
|
|
6b46
|
immune system-hydrolase-RNA |
cryo-EM (3.1 Å) |
Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P,
Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ,
Subramaniam S |
(2017) "Cryo-EM
Structures Reveal Mechanism and Inhibition of DNA
Targeting by a CRISPR-Cas Surveillance Complex."
Cell, 171, 414-426.e12. doi:
10.1016/j.cell.2017.09.006.
|
cryo-EM structure of type i-f crispr crrna-guided csy
surveillance complex with bound anti-crispr protein
acrf1 . SNAP output
|
|
6b47
|
immune system - RNA |
cryo-EM (3.2 Å) |
Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P,
Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ,
Subramaniam S |
(2017) "Cryo-EM
Structures Reveal Mechanism and Inhibition of DNA
Targeting by a CRISPR-Cas Surveillance Complex."
Cell, 171, 414-426.e12. doi:
10.1016/j.cell.2017.09.006.
|
cryo-EM structure of type i-f crispr crrna-guided csy
surveillance complex with bound anti-crispr protein
acrf2 . SNAP output
|
|
6b48
|
immune system - RNA |
cryo-EM (3.6 Å) |
Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P,
Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ,
Subramaniam S |
(2017) "Cryo-EM
Structures Reveal Mechanism and Inhibition of DNA
Targeting by a CRISPR-Cas Surveillance Complex."
Cell, 171, 414-426.e12. doi:
10.1016/j.cell.2017.09.006.
|
cryo-EM structure of type i-f crispr crrna-guided csy
surveillance complex with bound anti-crispr protein
acrf10 . SNAP output
|
|
6b4v
|
ribosome-antibiotic |
X-ray (3.4 Å) |
Svidritskiy E, Korostelev AA |
(2018) "Mechanism
of Inhibition of Translation Termination by Blasticidin
S." J. Mol. Biol., 430,
591-593. doi: 10.1016/j.jmb.2018.01.007.
|
Antibiotic blasticidin s and e. coli release factor 1
bound to the 70s ribosome . SNAP output
|
|
6bbo
|
hydrolase-RNA |
X-ray (3.428 Å) |
Shaban NM, Shi K, Lauer KV, Carpenter MA, Richards
CM, Salamango D, Wang J, Lopresti MW, Banerjee S,
Levin-Klein R, Brown WL, Aihara H, Harris RS |
(2018) "The
Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is
Regulated by an RNA-Mediated Dimerization
Mechanism." Mol. Cell,
69, 75-86.e9. doi: 10.1016/j.molcel.2017.12.010.
|
Crystal structure of human apobec3h-RNA complex .
SNAP output
|
|
6bjg
|
RNA binding protein |
X-ray (2.29 Å) |
Foss DV, Schirle NT, MacRae IJ, Pezacki JP |
(2019) "Structural
insights into interactions between viral suppressor of
RNA silencing protein p19 mutants and small RNAs."
Febs Open Bio, 9, 1042-1051.
doi: 10.1002/2211-5463.12644.
|
Cirv p19 mutant t111h in complex with sirna . SNAP output
|
|
6bjh
|
RNA binding protein |
X-ray (2.58 Å) |
Foss DV, Schirle NT, MacRae IJ, Pezacki JP |
(2019) "Structural
insights into interactions between viral suppressor of
RNA silencing protein p19 mutants and small RNAs."
Febs Open Bio, 9, 1042-1051.
doi: 10.1002/2211-5463.12644.
|
Cirv p19 mutant t111s in complex with sirna . SNAP output
|
|
6bjv
|
RNA binding protein |
X-ray (2.198 Å) |
Foss DV, Schirle NT, MacRae IJ, Pezacki JP |
(2019) "Structural
insights into interactions between viral suppressor of
RNA silencing protein p19 mutants and small RNAs."
Febs Open Bio, 9, 1042-1051.
doi: 10.1002/2211-5463.12644.
|
Cirv p19 protein in complex with sirna . SNAP output
|
|
6bjy
|
RNA binding protein-RNA |
X-ray (3.46 Å) |
Gumpper RH, Li W, Castaneda CH, Scuderi MJ, Bashkin
JK, Luo M |
(2018) "A
Polyamide Inhibits Replication of Vesicular Stomatitis
Virus by Targeting RNA in the Nucleocapsid." J.
Virol., 92. doi: 10.1128/JVI.00146-18.
|
Vsv nucleocapsid with polyamide bound . SNAP output
|
|
6bk8
|
RNA binding protein |
cryo-EM (3.3 Å) |
Liu S, Li X, Zhang L, Jiang J, Hill RC, Cui Y, Hansen
KC, Zhou ZH, Zhao R |
(2017) "Structure
of the yeast spliceosomal postcatalytic P complex."
Science, 358, 1278-1283. doi:
10.1126/science.aar3462.
|
S. cerevisiae spliceosomal post-catalytic p complex .
SNAP output
|
|
6boh
|
ribosome-antibiotic |
X-ray (3.4 Å) |
Svidritskiy E, Korostelev AA |
(2018) "Conformational
Control of Translation Termination on the 70S
Ribosome." Structure, 26,
821. doi: 10.1016/j.str.2018.04.001.
|
Antibiotic blasticidin s and e. coli release factor 1
(containing deletion 302-304) bound to the 70s ribosome
. SNAP output
|
|
6bok
|
ribosome |
X-ray (3.55 Å) |
Svidritskiy E, Korostelev AA |
(2018) "Conformational
Control of Translation Termination on the 70S
Ribosome." Structure, 26,
821. doi: 10.1016/j.str.2018.04.001.
|
E. coli release factor 1 (containing deletion 302-304)
bound to the 70s ribosome . SNAP output
|
|
6bu8
|
ribosome |
cryo-EM (3.5 Å) |
Loveland AB, Korostelev AA |
(2018) "Structural
dynamics of protein S1 on the 70S ribosome visualized
by ensemble cryo-EM." Methods,
137, 55-66. doi: 10.1016/j.ymeth.2017.12.004.
|
70s ribosome with s1 domains 1 and 2 (class 1) .
SNAP output
|
|
6bu9
|
RNA binding protein-RNA |
cryo-EM (6.8 Å) |
Sinha NK, Iwasa J, Shen PS, Bass BL |
(2018) "Dicer
uses distinct modules for recognizing dsRNA
termini." Science, 359,
329-334. doi: 10.1126/science.aaq0921.
|
Drosophila dicer-2 bound to blunt dsrna . SNAP output
|
|
6buw
|
ribosome |
X-ray (3.5 Å) |
Hoffer ED, Maehigashi T, Fredrick K, Dunham CM |
(2019) "Ribosomal
ambiguity (ram) mutations promote the open (off) to
closed (on) transition and thereby increase
miscoding." Nucleic Acids Res.,
47, 1557-1563. doi: 10.1093/nar/gky1178.
|
Thermus thermophilus 70s complex containing 16s g299a
ram mutation and empty a site. . SNAP output
|
|
6by1
|
ribosome |
X-ray (3.94 Å) |
Amiri H, Noller HF |
(2019) "Structural
evidence for product stabilization by the ribosomal
mRNA helicase." Rna, 25,
364-375. doi: 10.1261/rna.068965.118.
|
E. coli ph03h9 complex . SNAP output
|
|
6bz6
|
ribosome |
X-ray (3.18 Å) |
Hoffer ED, Maehigashi T, Fredrick K, Dunham CM |
(2019) "Ribosomal
ambiguity (ram) mutations promote the open (off) to
closed (on) transition and thereby increase
miscoding." Nucleic Acids Res.,
47, 1557-1563. doi: 10.1093/nar/gky1178.
|
Thermus thermophilus 70s complex containing 16s g347u
ram mutation and empty a site . SNAP output
|
|
6bz7
|
ribosome |
X-ray (3.68 Å) |
Hoffer ED, Maehigashi T, Fredrick K, Dunham CM |
(2019) "Ribosomal
ambiguity (ram) mutations promote the open (off) to
closed (on) transition and thereby increase
miscoding." Nucleic Acids Res.,
47, 1557-1563. doi: 10.1093/nar/gky1178.
|
Thermus thermophilus 70s containing 16s g299a point
mutation and near-cognate asl leucine in a site. .
SNAP output
|
|
6bz8
|
ribosome |
X-ray (3.74 Å) |
Hoffer ED, Maehigashi T, Fredrick K, Dunham CM |
(2019) "Ribosomal
ambiguity (ram) mutations promote the open (off) to
closed (on) transition and thereby increase
miscoding." Nucleic Acids Res.,
47, 1557-1563. doi: 10.1093/nar/gky1178.
|
Thermus thermophilus 70s containing 16s g347u point
mutation and near-cognate asl leucine in a site .
SNAP output
|
|
6c0f
|
ribosome |
cryo-EM (3.7 Å) |
Sanghai ZA, Miller L, Molloy KR, Barandun J, Hunziker
M, Chaker-Margot M, Wang J, Chait BT, Klinge S |
(2018) "Modular
assembly of the nucleolar pre-60S ribosomal
subunit." Nature, 556,
126-129. doi: 10.1038/nature26156.
|
Yeast nucleolar pre-60s ribosomal subunit (state 2) .
SNAP output
|
|
6c4h
|
ribosomal protein-RNA |
cryo-EM (3.1 Å) |
Zeng F, Jin H |
(2018) "Conformation
of methylated GGQ in the Peptidyl Transferase Center
during Translation Termination." Sci Rep,
8, 2349. doi: 10.1038/s41598-018-20107-8.
|
Conformation of methylated ggq in the peptidyl
transferase center during translation termination (ptc
region) . SNAP
output
|
|
6c4i
|
ribosome |
cryo-EM (3.24 Å) |
Zeng F, Jin H |
(2018) "Conformation
of methylated GGQ in the Peptidyl Transferase Center
during Translation Termination." Sci Rep,
8, 2349. doi: 10.1038/s41598-018-20107-8.
|
Conformation of methylated ggq in the peptidyl
transferase center during translation termination .
SNAP output
|
|
6c5l
|
ribosome |
X-ray (3.2 Å) |
Zeng F, Jin H |
(2018) "Conformation
of methylated GGQ in the Peptidyl Transferase Center
during Translation Termination." Sci Rep,
8, 2349. doi: 10.1038/s41598-018-20107-8.
|
Conformation of methylated ggq in the peptidyl
transferase center during translation termination (t.
thermophilus) . SNAP
output
|
|
6c6k
|
RNA binding protein-RNA |
X-ray (2.54 Å) |
Johnson B, VanBlargan LA, Xu W, White JP, Shan C, Shi
PY, Zhang R, Adhikari J, Gross ML, Leung DW, Diamond MS,
Amarasinghe GK |
(2018) "Human
IFIT3 Modulates IFIT1 RNA Binding Specificity and
Protein Stability." Immunity,
48, 487-499.e5. doi: 10.1016/j.immuni.2018.01.014.
|
Structural basis for preferential recognition of cap 0
RNA by a human ifit1-ifit3 protein complex . SNAP output
|
|
6cae
|
ribosome-inhibitor |
X-ray (2.6 Å) |
Pantel L, Florin T, Dobosz-Bartoszek M, Racine E,
Sarciaux M, Serri M, Houard J, Campagne JM, de Figueiredo
RM, Midrier C, Gaudriault S, Givaudan A, Lanois A, Forst
S, Aumelas A, Cotteaux-Lautard C, Bolla JM, Vingsbo
Lundberg C, Huseby DL, Hughes D, Villain-Guillot P,
Mankin AS, Polikanov YS, Gualtieri M |
(2018) "Odilorhabdins,
Antibacterial Agents that Cause Miscoding by Binding at
a New Ribosomal Site." Mol. Cell,
70, 83-94.e7. doi: 10.1016/j.molcel.2018.03.001.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with noso-95179 antibiotic and
bound to mrna and a-, p- and e-site trnas at 2.6a
resolution . SNAP
output
|
|
6cao
|
ribosome |
X-ray (3.45 Å) |
Dao EH, Poitevin F, Sierra RG, Gati C, Rao Y, Ciftci
HI, Aksit F, McGurk A, Obrinski T, Mgbam P, Hayes B, De
Lichtenberg C, Pardo-Avila F, Corsepius N, Zhang L,
Seaberg MH, Hunter MS, Liang M, Koglin JE, Wakatsuki S,
Demirci H |
(2018) "Structure
of the 30S ribosomal decoding complex at ambient
temperature." RNA, 24,
1667-1676. doi: 10.1261/rna.067660.118.
|
Structure of the ribosomal decoding complex at ambient
temperature . SNAP
output
|
|
6cap
|
ribosome |
X-ray (3.4 Å) |
DeMirci H |
"Crystal Structure of 30S ribosomal subunit from
Thermus thermophilus in complex with Sisomicin." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus in complex with sisomicin . SNAP output
|
|
6caq
|
ribosome |
X-ray (3.4 Å) |
DeMirci H |
"Crystal Structure of 30S ribosomal subunit from
Thermus thermophilus." |
Crystal structure of 30s ribosomal subunit from thermus
thermophilus . SNAP
output
|
|
6car
|
ribosome |
X-ray (3.4 Å) |
O'Sullivan ME, Poitevin F, Sierra RG, Gati C, Dao EH,
Rao Y, Aksit F, Ciftci H, Corsepius N, Greenhouse R,
Hayes B, Hunter MS, Liang M, McGurk A, Mbgam P, Obrinsky
T, Pardo-Avila F, Seaberg MH, Cheng AG, Ricci AJ, DeMirci
H |
(2018) "Aminoglycoside
ribosome interactions reveal novel conformational
states at ambient temperature." Nucleic Acids
Res., 46, 9793-9804. doi:
10.1093/nar/gky693.
|
Serial femtosecond x-ray crystal structure of 30s
ribosomal subunit from thermus thermophilus in complex
with sisomicin . SNAP
output
|
|
6cas
|
ribosome |
X-ray (3.5 Å) |
O'Sullivan ME, Poitevin F, Sierra RG, Gati C, Dao EH,
Rao Y, Aksit F, Ciftci H, Corsepius N, Greenhouse R,
Hayes B, Hunter MS, Liang M, McGurk A, Mbgam P, Obrinsky
T, Pardo-Avila F, Seaberg MH, Cheng AG, Ricci AJ, DeMirci
H |
(2018) "Aminoglycoside
ribosome interactions reveal novel conformational
states at ambient temperature." Nucleic Acids
Res., 46, 9793-9804. doi:
10.1093/nar/gky693.
|
Serial femtosecond x-ray crystal structure of 30s
ribosomal subunit from thermus thermophilus in complex
with n1ms . SNAP
output
|
|
6cb1
|
ribosome |
cryo-EM (4.6 Å) |
Sanghai ZA, Miller L, Molloy KR, Barandun J, Hunziker
M, Chaker-Margot M, Wang J, Chait BT, Klinge S |
(2018) "Modular
assembly of the nucleolar pre-60S ribosomal
subunit." Nature, 556,
126-129. doi: 10.1038/nature26156.
|
Yeast nucleolar pre-60s ribosomal subunit (state 3) .
SNAP output
|
|
6cbd
|
RNA binding protein |
X-ray (2.203 Å) |
Sheu-Gruttadauria J, MacRae IJ |
(2018) "Phase
Transitions in the Assembly and Function of Human
miRISC." Cell, 173, 946.
doi: 10.1016/j.cell.2018.02.051.
|
Crystal structure of human argonaute2 bound to three
tryptophans . SNAP
output
|
|
6cf2
|
RNA binding protein-RNA |
X-ray (3.0 Å) |
Dearborn AD, Eren E, Watts NR, Palmer IW, Kaufman JD,
Steven AC, Wingfield PT |
(2018) "Structure
of an RNA Aptamer that Can Inhibit HIV-1 by Blocking
Rev-Cognate RNA (RRE) Binding and Rev-Rev
Association." Structure,
26, 1187. doi: 10.1016/j.str.2018.06.001.
|
Crystal structure of hiv-1 rev (residues 1-93)-RNA
aptamer complex . SNAP
output
|
|
6cfj
|
ribosome-inhibitor |
X-ray (2.8 Å) |
Tereshchenkov AG, Dobosz-Bartoszek M, Osterman IA,
Marks J, Sergeeva VA, Kasatsky P, Komarova ES,
Stavrianidi AN, Rodin IA, Konevega AL, Sergiev PV,
Sumbatyan NV, Mankin AS, Bogdanov AA, Polikanov YS |
(2018) "Binding
and Action of Amino Acid Analogs of Chloramphenicol
upon the Bacterial Ribosome." J. Mol.
Biol., 430, 842-852. doi:
10.1016/j.jmb.2018.01.016.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with histidyl-cam and bound to mrna
and a-, p-, and e-site trnas at 2.8a resolution .
SNAP output
|
|
6cfk
|
ribosome-inhibitor |
X-ray (2.7 Å) |
Tereshchenkov AG, Dobosz-Bartoszek M, Osterman IA,
Marks J, Sergeeva VA, Kasatsky P, Komarova ES,
Stavrianidi AN, Rodin IA, Konevega AL, Sergiev PV,
Sumbatyan NV, Mankin AS, Bogdanov AA, Polikanov YS |
(2018) "Binding
and Action of Amino Acid Analogs of Chloramphenicol
upon the Bacterial Ribosome." J. Mol.
Biol., 430, 842-852. doi:
10.1016/j.jmb.2018.01.016.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with d-histidyl-cam and bound to
protein y (yfia) at 2.7a resolution . SNAP output
|
|
6cfl
|
ribosome-inhibitor |
X-ray (2.6 Å) |
Tereshchenkov AG, Dobosz-Bartoszek M, Osterman IA,
Marks J, Sergeeva VA, Kasatsky P, Komarova ES,
Stavrianidi AN, Rodin IA, Konevega AL, Sergiev PV,
Sumbatyan NV, Mankin AS, Bogdanov AA, Polikanov YS |
(2018) "Binding
and Action of Amino Acid Analogs of Chloramphenicol
upon the Bacterial Ribosome." J. Mol.
Biol., 430, 842-852. doi:
10.1016/j.jmb.2018.01.016.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with lysyl-cam and bound to protein
y (yfia) at 2.6a resolution . SNAP output
|
|
6cmn
|
RNA binding protein-RNA |
X-ray (1.796 Å) |
Belashov IA, Crawford DW, Cavender CE, Dai P,
Beardslee PC, Mathews DH, Pentelute BL, McNaughton BR,
Wedekind JE |
(2018) "Structure
of HIV TAR in complex with a Lab-Evolved RRM provides
insight into duplex RNA recognition and synthesis of a
constrained peptide that impairs transcription."
Nucleic Acids Res., 46,
6401-6415. doi: 10.1093/nar/gky529.
|
Co-crystal structure of hiv-1 tar bound to lab-evolved
rrm tbp6.7 . SNAP
output
|
|
6cyt
|
transcription-RNA |
X-ray (3.5 Å) |
Schulze-Gahmen U, Hurley JH |
(2018) "Structural
mechanism for HIV-1 TAR loop recognition by Tat and the
super elongation complex." Proc. Natl. Acad.
Sci. U.S.A., 115, 12973-12978.
doi: 10.1073/pnas.1806438115.
|
Hiv-1 tar loop in complex with tat:aff4:p-tefb .
SNAP output
|
|
6czr
|
ribosome-antibiotic |
X-ray (3.14 Å) |
Serrano CM, Kanna Reddy HR, Eiler DR, Koch MR, Tresco
BIC, Barrows LR, VanderLinden RT, Testa CA, Sebahar PR,
Looper RE |
(2020) "Unifying the Aminohexopyranose- and
Peptidyl-Nucleoside Antibiotics: Implications for
Antibiotic Design." Angew.Chem.Int.Ed.Engl.,
132, 11426-11429. doi: 10.1002/ange.202003094.
|
The structure of amicetin bound to the 70s ribosome .
SNAP output
|
|
6d06
|
hydrolase-RNA |
X-ray (2.55 Å) |
Monteleone LR, Matthews MM, Palumbo CM, Thomas JM,
Zheng Y, Chiang Y, Fisher AJ, Beal PA |
(2019) "A
Bump-Hole Approach for Directed RNA Editing."
Cell Chem Biol, 26, 269. doi:
10.1016/j.chembiol.2018.10.025.
|
Human adar2d e488y mutant complexed with dsrna
containing an abasic site opposite the edited base .
SNAP output
|
|
6d12
|
RNA binding protein-RNA |
X-ray (2.205 Å) |
Eichhorn CD, Yang Y, Repeta L, Feigon J |
(2018) "Structural
basis for recognition of human 7SK long noncoding RNA
by the La-related protein Larp7." Proc. Natl.
Acad. Sci. U.S.A., 115,
E6457-E6466. doi: 10.1073/pnas.1806276115.
|
Crystal structure of c-terminal xrrm domain of human
larp7 bound to 7sk stem-loop 4 RNA . SNAP output
|
|
6d1v
|
isomerase-hydrolase-RNA |
X-ray (1.81 Å) |
Gao A, Vasilyev N, Luciano DJ, Levenson-Palmer R,
Richards J, Marsiglia WM, Traaseth NJ, Belasco JG,
Serganov A |
(2018) "Structural
and kinetic insights into stimulation of RppH-dependent
RNA degradation by the metabolic enzyme DapF."
Nucleic Acids Res., 46,
6841-6856. doi: 10.1093/nar/gky327.
|
Crystal structure of e. coli rpph-dapf complex, monomer
bound to RNA . SNAP
output
|
|
6d2u
|
peptide-RNA |
NMR |
Shortridge MD, Wille PT, Jones AN, Davidson A,
Bogdanovic J, Arts E, Karn J, Robinson JA, Varani G |
(2019) "An
ultra-high affinity ligand of HIV-1 TAR reveals the RNA
structure recognized by P-TEFb." Nucleic Acids
Res., 47, 1523-1531. doi:
10.1093/nar/gky1197.
|
Solution structure of a ultra-high affinity macrocycle
bound to hiv-1 tar RNA . SNAP output
|
|
6d2z
|
hydrolase-RNA |
X-ray (1.18 Å) |
Nomura Y, Roston D, Montemayor EJ, Cui Q, Butcher
SE |
(2018) "Structural
and mechanistic basis for preferential deadenylation of
U6 snRNA by Usb1." Nucleic Acids Res.,
46, 11488-11501. doi: 10.1093/nar/gky812.
|
Structure of human usb1 with uridine-adenosine,
inactive h208q mutant . SNAP output
|
|
6d30
|
hydrolase-RNA |
X-ray (1.17 Å) |
Nomura Y, Roston D, Montemayor EJ, Cui Q, Butcher
SE |
(2018) "Structural
and mechanistic basis for preferential deadenylation of
U6 snRNA by Usb1." Nucleic Acids Res.,
46, 11488-11501. doi: 10.1093/nar/gky812.
|
Structure of human usb1 with uridine-uridine, inactive
h208q mutant . SNAP
output
|
|
6d90
|
ribosome |
cryo-EM (3.2 Å) |
Pisareva VP, Pisarev AV, Fernandez IS |
(2018) "Dual
tRNA mimicry in the Cricket Paralysis Virus IRES
uncovers an unexpected similarity with the Hepatitis C
Virus IRES." Elife, 7.
doi: 10.7554/eLife.34062.
|
Mammalian 80s ribosome with a double translocated
crpv-ires, p-site trna and erf1. . SNAP output
|
|
6d9j
|
ribosome |
cryo-EM (3.2 Å) |
Pisareva VP, Pisarev AV, Fernandez IS |
(2018) "Dual
tRNA mimicry in the Cricket Paralysis Virus IRES
uncovers an unexpected similarity with the Hepatitis C
Virus IRES." Elife, 7.
doi: 10.7554/eLife.34062.
|
Mammalian 80s ribosome with a double translocated
crpv-ires, p-sitetrna and erf1. . SNAP output
|
|
6db8
|
RNA-immune system |
X-ray (1.87 Å) |
Shelke SA, Shao Y, Laski A, Koirala D, Weissman BP,
Fuller JR, Tan X, Constantin TP, Waggoner AS, Bruchez MP,
Armitage BA, Piccirilli JA |
(2018) "Structural
basis for activation of fluorogenic dyes by an RNA
aptamer lacking a G-quadruplex motif." Nat
Commun, 9, 4542. doi: 10.1038/s41467-018-06942-3.
|
Structural basis for promiscuous binding and activation
of fluorogenic dyes by dir2s RNA aptamer . SNAP output
|
|
6db9
|
RNA-immune system |
X-ray (2.025 Å) |
Shelke SA, Shao Y, Laski A, Koirala D, Weissman BP,
Fuller JR, Tan X, Constantin TP, Waggoner AS, Bruchez MP,
Armitage BA, Piccirilli JA |
(2018) "Structural
basis for activation of fluorogenic dyes by an RNA
aptamer lacking a G-quadruplex motif." Nat
Commun, 9, 4542. doi: 10.1038/s41467-018-06942-3.
|
Structural basis for promiscuous binding and activation
of fluorogenic dyes by dir2s RNA aptamer . SNAP output
|
|
6dcb
|
transferase-RNA |
X-ray (1.998 Å) |
Yang Y, Eichhorn CD, Wang Y, Cascio D, Feigon J |
(2019) "Structural
basis of 7SK RNA 5'-gamma-phosphate methylation and
retention by MePCE." Nat. Chem. Biol.,
15, 132-140. doi: 10.1038/s41589-018-0188-z.
|
Structure of methylphosphate capping enzyme
methyltransferase domain in complex with 5' end of 7sk
RNA . SNAP output
|
|
6dcc
|
transferase-RNA |
X-ray (2.1 Å) |
Yang Y, Eichhorn CD, Wang Y, Cascio D, Feigon J |
(2019) "Structural
basis of 7SK RNA 5'-gamma-phosphate methylation and
retention by MePCE." Nat. Chem. Biol.,
15, 132-140. doi: 10.1038/s41589-018-0188-z.
|
Structure of methylphosphate capping enzyme
methyltransferase domain in complex with 5' end of 7sk
RNA . SNAP output
|
|
6dcl
|
RNA binding protein-RNA |
X-ray (2.497 Å) |
Kooshapur H, Choudhury NR, Simon B, Muhlbauer M,
Jussupow A, Fernandez N, Jones AN, Dallmann A, Gabel F,
Camilloni C, Michlewski G, Caceres JF, Sattler M |
(2018) "Structural
basis for terminal loop recognition and stimulation of
pri-miRNA-18a processing by hnRNP A1." Nat
Commun, 9, 2479. doi: 10.1038/s41467-018-04871-9.
|
Crystal structure of up1 bound to pri-mirna-18a
terminal loop . SNAP
output
|
|
6ddd
|
ribosome-antibiotic |
cryo-EM (3.1 Å) |
Belousoff MJ, Venugopal H, Wright A, Seoner S, Stuart
I, Stubenrauch C, Bamert RS, Lupton DW, Lithgow T |
(2019) "cryoEM-Guided
Development of Antibiotics for Drug-Resistant
Bacteria." ChemMedChem,
14, 527-531. doi: 10.1002/cmdc.201900042.
|
Structure of the 50s ribosomal subunit from methicillin
resistant staphylococcus aureus in complex with the
oxazolidinone antibiotic lzd-5 . SNAP output
|
|
6ddg
|
ribosome-antibiotic |
cryo-EM (3.1 Å) |
Belousoff MJ, Venugopal H, Wright A, Seoner S, Stuart
I, Stubenrauch C, Bamert RS, Lupton DW, Lithgow T |
(2019) "cryoEM-Guided
Development of Antibiotics for Drug-Resistant
Bacteria." ChemMedChem,
14, 527-531. doi: 10.1002/cmdc.201900042.
|
Structure of the 50s ribosomal subunit from methicillin
resistant staphylococcus aureus in complex with the
oxazolidinone antibiotic lzd-6 . SNAP output
|
|
6dnc
|
ribosome |
cryo-EM (3.7 Å) |
Svidritskiy E, Demo G, Korostelev AA |
(2018) "Mechanism
of premature translation termination on a sense
codon." J. Biol. Chem.,
293, 12472-12479. doi: 10.1074/jbc.AW118.003232.
|
E.coli rf1 bound to e.coli 70s ribosome in response to
uau sense a-site codon . SNAP output
|
|
6dnh
|
RNA binding protein-RNA |
cryo-EM (3.4 Å) |
Sun Y, Zhang Y, Hamilton K, Manley JL, Shi Y, Walz T,
Tong L |
(2018) "Molecular
basis for the recognition of the human AAUAAA
polyadenylation signal." Proc. Natl. Acad. Sci.
U.S.A., 115, E1419-E1428. doi:
10.1073/pnas.1718723115.
|
cryo-EM structure of human cpsf-160-wdr33-cpsf-30-pas
RNA complex at 3.4 Å resolution . SNAP output
|
|
6dtd
|
hydrolase-RNA |
X-ray (1.65 Å) |
Slaymaker IM, Mesa P, Kellner MJ, Kannan S, Brignole
E, Koob J, Feliciano PR, Stella S, Abudayyeh OO,
Gootenberg JS, Strecker J, Montoya G, Zhang F |
(2019) "High-Resolution
Structure of Cas13b and Biochemical Characterization of
RNA Targeting and Cleavage." Cell Rep,
26, 3741-3751.e5. doi: 10.1016/j.celrep.2019.02.094.
|
High-resolution crystal structure of cas13b from
prevotella buccae . SNAP
output
|
|
6dti
|
ribosome |
X-ray (3.54 Å) |
Vangaveti S, Cantara WA, Spears JL, DeMirci H, Murphy
IV FV, Ranganathan SV, Sarachan KL, Agris PF |
(2020) "A
Structural Basis for Restricted Codon Recognition
Mediated by 2-thiocytidine in tRNA Containing a Wobble
Position Inosine." J.Mol.Biol.,
432, 913-929. doi: 10.1016/j.jmb.2019.12.016.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with an unmodifed anticodon stem loop
(asl) of escherichia coli transfer RNA arginine 2
(trnaarg2) bound to an mrna with an cgu-codon in the
a-site and paromomycin . SNAP output
|
|
6du4
|
transferase-RNA |
X-ray (1.7 Å) |
Doxtader KA, Wang P, Scarborough AM, Seo D, Conrad
NK, Nam Y |
(2018) "Structural
Basis for Regulation of METTL16, an
S-Adenosylmethionine Homeostasis Factor." Mol.
Cell, 71, 1001-1011.e4. doi:
10.1016/j.molcel.2018.07.025.
|
Crystal structure of hmettl16 catalytic domain in
complex with mat2a 3'utr hairpin 1 . SNAP output
|
|
6du5
|
transferase-RNA |
X-ray (3.006 Å) |
Doxtader KA, Wang P, Scarborough AM, Seo D, Conrad
NK, Nam Y |
(2018) "Structural
Basis for Regulation of METTL16, an
S-Adenosylmethionine Homeostasis Factor." Mol.
Cell, 71, 1001-1011.e4. doi:
10.1016/j.molcel.2018.07.025.
|
Crystal structure of hmettl16 catalytic domain in
complex with mat2a 3'utr hairpin 6 . SNAP output
|
|
6duq
|
transcription-RNA |
X-ray (3.7 Å) |
Lawson MR, Ma W, Bellecourt MJ, Artsimovitch I,
Martin A, Landick R, Schulten K, Berger JM |
(2018) "Mechanism
for the Regulated Control of Bacterial Transcription
Termination by a Universal Adaptor Protein."
Mol. Cell, 71, 911-922.e4.
doi: 10.1016/j.molcel.2018.07.014.
|
Structure of a rho-nusg kow domain complex . SNAP output
|
|
6dzi
|
ribosome |
cryo-EM (3.46 Å) |
Li Y, Sharma MR, Koripella RK, Yang Y, Kaushal PS,
Lin Q, Wade JT, Gray TA, Derbyshire KM, Agrawal RK, Ojha
AK |
(2018) "Zinc
depletion induces ribosome hibernation in
mycobacteria." Proc. Natl. Acad. Sci.
U.S.A., 115, 8191-8196. doi:
10.1073/pnas.1804555115.
|
cryo-EM structure of mycobacterium smegmatis 70s
c(minus) ribosome 70s-mpy complex . SNAP output
|
|
6dzk
|
ribosome |
cryo-EM (3.6 Å) |
Li Y, Sharma MR, Koripella RK, Yang Y, Kaushal PS,
Lin Q, Wade JT, Gray TA, Derbyshire KM, Agrawal RK, Ojha
AK |
(2018) "Zinc
depletion induces ribosome hibernation in
mycobacteria." Proc. Natl. Acad. Sci.
U.S.A., 115, 8191-8196. doi:
10.1073/pnas.1804555115.
|
cryo-EM structure of mycobacterium smegmatis c(minus)
30s ribosomal subunit with mpy . SNAP output
|
|
6dzp
|
ribosome |
cryo-EM (3.42 Å) |
Li Y, Sharma MR, Koripella RK, Yang Y, Kaushal PS,
Lin Q, Wade JT, Gray TA, Derbyshire KM, Agrawal RK, Ojha
AK |
(2018) "Zinc
depletion induces ribosome hibernation in
mycobacteria." Proc. Natl. Acad. Sci.
U.S.A., 115, 8191-8196. doi:
10.1073/pnas.1804555115.
|
cryo-EM structure of mycobacterium smegmatis c(minus)
50s ribosomal subunit . SNAP output
|
|
6e0o
|
transferase-RNA |
X-ray (1.25 Å) |
Whiteley AT, Eaglesham JB, de Oliveira Mann CC,
Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King
DS, Lee ASY, Mekalanos JJ, Kranzusch PJ |
(2019) "Bacterial
cGAS-like enzymes synthesize diverse nucleotide
signals." Nature, 567,
194-199. doi: 10.1038/s41586-019-0953-5.
|
Structure of elizabethkingia meningoseptica cdne cyclic
dinucleotide synthase with pppa[3'-5']pa . SNAP output
|
|
6e4p
|
RNA binding protein-RNA |
X-ray (1.949 Å) |
Travis B, Shaw PLR, Liu B, Ravindra K, Iliff H,
Al-Hashimi HM, Schumacher MA |
(2019) "The RRM
of the kRNA-editing protein TbRGG2 uses multiple
surfaces to bind and remodel RNA." Nucleic
Acids Res., 47, 2130-2142. doi:
10.1093/nar/gky1259.
|
Structure of the t. brucei rrm domain in complex with
RNA . SNAP output
|
|
6e9e
|
RNA binding protein-RNA |
cryo-EM (3.4 Å) |
Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X,
Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis
D |
(2018) "Structural
Basis for the RNA-Guided Ribonuclease Activity of
CRISPR-Cas13d." Cell,
175, 212-223.e17. doi: 10.1016/j.cell.2018.09.001.
|
Escas13d-crrna binary complex . SNAP output
|
|
6e9f
|
RNA binding protein-RNA |
cryo-EM (3.3 Å) |
Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X,
Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis
D |
(2018) "Structural
Basis for the RNA-Guided Ribonuclease Activity of
CRISPR-Cas13d." Cell,
175, 212-223.e17. doi: 10.1016/j.cell.2018.09.001.
|
Escas13d-crrna-target RNA ternary complex . SNAP output
|
|
6een
|
RNA binding protein-RNA |
X-ray (2.01 Å) |
Schmidberger JW, Bond CS |
"Crystal structure of a designer Pentatrico Peptide
RNA binding protein, bound to a complex RNA target and
featuring an infinite superhelix and
microheterogeneity." |
Crystal structure of a designer pentatrico peptide RNA
binding protein, bound to a complex RNA target and
featuring an infinite superhelix and
microheterogeneity. . SNAP output
|
|
6elz
|
ribosome |
cryo-EM (3.3 Å) |
Kater L, Thoms M, Barrio-Garcia C, Cheng J, Ismail S,
Ahmed YL, Bange G, Kressler D, Berninghausen O, Sinning
I, Hurt E, Beckmann R |
(2017) "Visualizing
the Assembly Pathway of Nucleolar Pre-60S
Ribosomes." Cell, 171,
1599-1610.e14. doi: 10.1016/j.cell.2017.11.039.
|
State e (tap-flag-ytm1 e80a) - visualizing the assembly
pathway of nucleolar pre-60s ribosomes . SNAP output
|
|
6em1
|
ribosome |
cryo-EM (3.6 Å) |
Kater L, Thoms M, Barrio-Garcia C, Cheng J, Ismail S,
Ahmed YL, Bange G, Kressler D, Berninghausen O, Sinning
I, Hurt E, Beckmann R |
(2017) "Visualizing
the Assembly Pathway of Nucleolar Pre-60S
Ribosomes." Cell, 171,
1599-1610.e14. doi: 10.1016/j.cell.2017.11.039.
|
State c (nsa1-tap flag-ytm1) - visualizing the assembly
pathway of nucleolar pre-60s ribosomes . SNAP output
|
|
6eml
|
ribosome |
cryo-EM (3.6 Å) |
Heuer A, Thomson E, Schmidt C, Berninghausen O,
Becker T, Hurt E, Beckmann R |
(2017) "Cryo-EM
structure of a late pre-40S ribosomal subunit
fromSaccharomyces cerevisiae." Elife,
6. doi: 10.7554/eLife.30189.
|
cryo-EM structure of a late pre-40s ribosomal subunit
from saccharomyces cerevisiae . SNAP output
|
|
6enf
|
ribosome |
cryo-EM (3.2 Å) |
Huter P, Arenz S, Bock LV, Graf M, Frister JO, Heuer
A, Peil L, Starosta AL, Wohlgemuth I, Peske F, Novacek J,
Berninghausen O, Grubmuller H, Tenson T, Beckmann R,
Rodnina MV, Vaiana AC, Wilson DN |
(2017) "Structural
Basis for Polyproline-Mediated Ribosome Stalling and
Rescue by the Translation Elongation Factor EF-P."
Mol. Cell, 68, 515-527.e6.
doi: 10.1016/j.molcel.2017.10.014.
|
cryo-EM structure of a polyproline-stalled ribosome in
the absence of ef-p . SNAP output
|
|
6enj
|
ribosome |
cryo-EM (3.7 Å) |
Huter P, Arenz S, Bock LV, Graf M, Frister JO, Heuer
A, Peil L, Starosta AL, Wohlgemuth I, Peske F, Novacek J,
Berninghausen O, Grubmuller H, Tenson T, Beckmann R,
Rodnina MV, Vaiana AC, Wilson DN |
(2017) "Structural
Basis for Polyproline-Mediated Ribosome Stalling and
Rescue by the Translation Elongation Factor EF-P."
Mol. Cell, 68, 515-527.e6.
doi: 10.1016/j.molcel.2017.10.014.
|
Polyproline-stalled ribosome in the presence of a+p
site trna and elongation-factor p (ef-p) . SNAP output
|
|
6enu
|
ribosome |
cryo-EM (3.1 Å) |
Huter P, Arenz S, Bock LV, Graf M, Frister JO, Heuer
A, Peil L, Starosta AL, Wohlgemuth I, Peske F, Novacek J,
Berninghausen O, Grubmuller H, Tenson T, Beckmann R,
Rodnina MV, Vaiana AC, Wilson DN |
(2017) "Structural
Basis for Polyproline-Mediated Ribosome Stalling and
Rescue by the Translation Elongation Factor EF-P."
Mol. Cell, 68, 515-527.e6.
doi: 10.1016/j.molcel.2017.10.014.
|
Polyproline-stalled ribosome in the presence of
elongation-factor p (ef-p) . SNAP output
|
|
6eri
|
ribosome |
cryo-EM (3.0 Å) |
Boerema AP, Aibara S, Paul B, Tobiasson V, Kimanius
D, Forsberg BO, Wallden K, Lindahl E, Amunts A |
(2018) "Structure
of the chloroplast ribosome with chl-RRF and
hibernation-promoting factor." Nat Plants,
4, 212-217. doi: 10.1038/s41477-018-0129-6.
|
Structure of the chloroplast ribosome with chl-rrf and
hibernation-promoting factor . SNAP output
|
|
6evj
|
viral protein |
X-ray (3.9 Å) |
Pflug A, Gaudon S, Resa-Infante P, Lethier M, Reich
S, Schulze WM, Cusack S |
(2018) "Capped
RNA primer binding to influenza polymerase and
implications for the mechanism of cap-binding
inhibitors." Nucleic Acids Res.,
46, 956-971. doi: 10.1093/nar/gkx1210.
|
Crystal structure of bat influenza a-h17n10 polymerase
with viral RNA promoter and capped RNA primer .
SNAP output
|
|
6evk
|
viral protein |
X-ray (2.9 Å) |
Pflug A, Gaudon S, Resa-Infante P, Lethier M, Reich
S, Schulze WM, Cusack S |
(2018) "Capped
RNA primer binding to influenza polymerase and
implications for the mechanism of cap-binding
inhibitors." Nucleic Acids Res.,
46, 956-971. doi: 10.1093/nar/gkx1210.
|
Crystal structure of bat influenza a-h17n10 polymerase
with viral RNA promoter and cap analogue m7gtp .
SNAP output
|
|
6exn
|
splicing |
cryo-EM (3.7 Å) |
Wilkinson ME, Fica SM, Galej WP, Norman CM, Newman
AJ, Nagai K |
(2017) "Postcatalytic
spliceosome structure reveals mechanism of 3'-splice
site selection." Science,
358, 1283-1288. doi: 10.1126/science.aar3729.
|
Post-catalytic p complex spliceosome with 3' splice
site docked . SNAP
output
|
|
6f3h
|
hydrolase |
X-ray (2.703 Å) |
Razew M, Warkocki Z, Taube M, Kolondra A,
Czarnocki-Cieciura M, Nowak E, Labedzka-Dmoch K, Kawinska
A, Piatkowski J, Golik P, Kozak M, Dziembowski A, Nowotny
M |
(2018) "Structural
analysis of mtEXO mitochondrial RNA degradosome reveals
tight coupling of nuclease and helicase
components." Nat Commun,
9, 97. doi: 10.1038/s41467-017-02570-5.
|
Crystal structure of dss1 exoribonuclease active site
mutant d477n from candida glabrata . SNAP output
|
|
6f4a
|
hydrolase |
X-ray (3.55 Å) |
Razew M, Warkocki Z, Taube M, Kolondra A,
Czarnocki-Cieciura M, Nowak E, Labedzka-Dmoch K, Kawinska
A, Piatkowski J, Golik P, Kozak M, Dziembowski A, Nowotny
M |
(2018) "Structural
analysis of mtEXO mitochondrial RNA degradosome reveals
tight coupling of nuclease and helicase
components." Nat Commun,
9, 97. doi: 10.1038/s41467-017-02570-5.
|
Yeast mitochondrial RNA degradosome complex mtexo .
SNAP output
|
|
6f4g
|
splicing |
X-ray (1.9 Å) |
Weber G, DeKoster GT, Holton N, Hall KB, Wahl MC |
(2018) "Molecular
principles underlying dual RNA specificity in the
Drosophila SNF protein." Nat Commun,
9, 2220. doi: 10.1038/s41467-018-04561-6.
|
'crystal structure of the drosophila melanogaster
snf-u2a'-u2-sl4 complex . SNAP output
|
|
6f4h
|
splicing |
X-ray (2.0 Å) |
Weber G, DeKoster GT, Holton N, Hall KB, Wahl MC |
(2018) "Molecular
principles underlying dual RNA specificity in the
Drosophila SNF protein." Nat Commun,
9, 2220. doi: 10.1038/s41467-018-04561-6.
|
Crystal structure of the drosophila melanogaster
snf-u1-sl2 complex . SNAP output
|
|
6f5o
|
viral protein |
cryo-EM (9.8 Å) |
Serna Martin I, Hengrung N, Renner M, Sharps J,
Martinez-Alonso M, Masiulis S, Grimes JM, Fodor E |
(2018) "A
Mechanism for the Activation of the Influenza Virus
Transcriptase." Mol. Cell,
70, 1101-1110.e4. doi: 10.1016/j.molcel.2018.05.011.
|
A mechanism for the activation of the influenza virus
transcriptase . SNAP
output
|
|
6fai
|
ribosome |
cryo-EM (3.4 Å) |
Scaiola A, Pena C, Weisser M, Bohringer D, Leibundgut
M, Klingauf-Nerurkar P, Gerhardy S, Panse VG, Ban N |
(2018) "Structure
of a eukaryotic cytoplasmic pre-40S ribosomal
subunit." EMBO J., 37.
doi: 10.15252/embj.201798499.
|
Structure of a eukaryotic cytoplasmic pre-40s ribosomal
subunit . SNAP
output
|
|
6fec
|
ribosome |
cryo-EM (6.3 Å) |
Eliseev B, Yeramala L, Leitner A, Karuppasamy M,
Raimondeau E, Huard K, Alkalaeva E, Aebersold R,
Schaffitzel C |
(2018) "Structure
of a human cap-dependent 48S translation pre-initiation
complex." Nucleic Acids Res.,
46, 2678-2689. doi: 10.1093/nar/gky054.
|
Human cap-dependent 48s pre-initiation complex .
SNAP output
|
|
6ff4
|
splicing |
cryo-EM (3.4 Å) |
Haselbach D, Komarov I, Agafonov DE, Hartmuth K, Graf
B, Dybkov O, Urlaub H, Kastner B, Luhrmann R, Stark
H |
(2018) "Structure
and Conformational Dynamics of the Human Spliceosomal
BactComplex." Cell, 172,
454-464.e11. doi: 10.1016/j.cell.2018.01.010.
|
Human bact spliceosome core structure . SNAP output
|
|
6ff7
|
splicing |
cryo-EM (4.5 Å) |
Haselbach D, Komarov I, Agafonov DE, Hartmuth K, Graf
B, Dybkov O, Urlaub H, Kastner B, Luhrmann R, Stark
H |
(2018) "Structure
and Conformational Dynamics of the Human Spliceosomal
BactComplex." Cell, 172,
454-464.e11. doi: 10.1016/j.cell.2018.01.010.
|
Human bact spliceosome core structure . SNAP output
|
|
6fhh
|
viral protein |
X-ray (2.7 Å) |
Claron M, Lukarska M, Uhrig U, Sehr P, Drncova P,
Lewis JD, Will DW, Cusack S |
"Towards New Anti-Influenza Therapeutics:
Structure-Activity Relationships in the Interaction
between Heterotrimeric Influenza Polymerase and Pol II
C-terminal domain." |
Crystal structure of bat influenza a-h17n10 polymerase
with viral RNA promoter bound to a 22-mer modified pol
ii ctd peptide with serine 5 thiophosphorylated. .
SNAP output
|
|
6fhi
|
viral protein |
X-ray (2.8 Å) |
Claron M, Lukarska M, Uhrig U, Sehr P, Drncova P,
Lewis JD, Will DW, Cusack S |
"Towards New Anti-Influenza Therapeutics:
Structure-Activity Relationships in the Interaction
between Heterotrimeric Influenza Polymerase and Pol II
C-terminal domain." |
Crystal structure of bat influenza a-h17n10 polymerase
with viral RNA promoter bound to a 19-mer serine 5
phosphorylated pol ii ctd peptide with a truncated
linker. . SNAP
output
|
|
6fkr
|
ribosome |
X-ray (3.2 Å) |
Mardirossian M, Perebaskine N, Benincasa M, Gambato
S, Hofmann S, Huter P, Muller C, Hilpert K, Innis CA,
Tossi A, Wilson DN |
(2018) "The
Dolphin Proline-Rich Antimicrobial Peptide Tur1A
Inhibits Protein Synthesis by Targeting the Bacterial
Ribosome." Cell Chem Biol,
25, 530-539.e7. doi: 10.1016/j.chembiol.2018.02.004.
|
Crystal structure of the dolphin proline-rich
antimicrobial peptide tur1a bound to the thermus
thermophilus 70s ribosome . SNAP output
|
|
6fpq
|
RNA binding protein |
X-ray (1.42 Å) |
Stowell JAW, Wagstaff JL, Hill CH, Yu M, McLaughlin
SH, Freund SMV, Passmore LA |
(2018) "A
low-complexity region in the YTH domain protein Mmi1
enhances RNA binding." J. Biol. Chem.,
293, 9210-9222. doi: 10.1074/jbc.RA118.002291.
|
Structure of s. pombe mmi1 in complex with 7-mer RNA .
SNAP output
|
|
6fpx
|
RNA binding protein |
X-ray (1.97 Å) |
Stowell JAW, Wagstaff JL, Hill CH, Yu M, McLaughlin
SH, Freund SMV, Passmore LA |
(2018) "A
low-complexity region in the YTH domain protein Mmi1
enhances RNA binding." J. Biol. Chem.,
293, 9210-9222. doi: 10.1074/jbc.RA118.002291.
|
Structure of s. pombe mmi1 in complex with 11-mer RNA .
SNAP output
|
|
6fq3
|
RNA binding protein |
X-ray (1.901 Å) |
Kumari P, Aeschimann F, Gaidatzis D, Keusch JJ, Ghosh
P, Neagu A, Pachulska-Wieczorek K, Bujnicki JM, Gut H,
Grosshans H, Ciosk R |
(2018) "Evolutionary
plasticity of the NHL domain underlies distinct
solutions to RNA recognition." Nat Commun,
9, 1549. doi: 10.1038/s41467-018-03920-7.
|
Crystal structure of danio rerio lin41 filamin-nhl
domains in complex with lin-29a 5'utr 13mer RNA .
SNAP output
|
|
6fql
|
RNA binding protein |
X-ray (2.349 Å) |
Kumari P, Aeschimann F, Gaidatzis D, Keusch JJ, Ghosh
P, Neagu A, Pachulska-Wieczorek K, Bujnicki JM, Gut H,
Grosshans H, Ciosk R |
(2018) "Evolutionary
plasticity of the NHL domain underlies distinct
solutions to RNA recognition." Nat Commun,
9, 1549. doi: 10.1038/s41467-018-03920-7.
|
Crystal structure of danio rerio lin41 filamin-nhl
domains in complex with mab-10 3'utr 13mer RNA .
SNAP output
|
|
6fqr
|
RNA binding protein |
X-ray (2.1 Å) |
Jia M, Gut H, Chao JA |
(2018) "Structural
basis of IMP3 RRM12 recognition of RNA."
RNA, 24, 1659-1666. doi:
10.1261/rna.065649.118.
|
Crystal structure of imp3 rrm12 in complex with RNA
(cccc) . SNAP output
|
|
6fsz
|
RNA |
cryo-EM (4.6 Å) |
Schuller JM, Falk S, Fromm L, Hurt E, Conti E |
(2018) "Structure
of the nuclear exosome captured on a maturing
preribosome." Science,
360, 219-222. doi: 10.1126/science.aar5428.
|
Structure of the nuclear RNA exosome . SNAP output
|
|
6ft6
|
RNA |
cryo-EM (3.9 Å) |
Schuller JM, Falk S, Fromm L, Hurt E, Conti E |
(2018) "Structure
of the nuclear exosome captured on a maturing
preribosome." Science,
360, 219-222. doi: 10.1126/science.aar5428.
|
Structure of the nop53 pre-60s particle bound to the
exosome nuclear cofactors . SNAP output
|
|
6fuw
|
RNA binding protein |
cryo-EM (3.07 Å) |
Clerici M, Faini M, Muckenfuss LM, Aebersold R, Jinek
M |
(2018) "Structural
basis of AAUAAA polyadenylation signal recognition by
the human CPSF complex." Nat. Struct. Mol.
Biol., 25, 135-138. doi: 10.1038/s41594-017-0020-6.
|
cryo-EM structure of the human cpsf160-wdr33-cpsf30
complex bound to the pas aauaaa motif at 3.1 angstrom
resolution . SNAP
output
|
|
6fxc
|
ribosome |
cryo-EM (6.76 Å) |
Matzov D, Aibara S, Basu A, Zimmerman E, Bashan A,
Yap MF, Amunts A, Yonath AE |
(2017) "The
cryo-EM structure of hibernating 100S ribosome dimer
from pathogenic Staphylococcus aureus." Nat
Commun, 8, 723. doi: 10.1038/s41467-017-00753-8.
|
The cryo-EM structure of hibernating 100s ribosome
dimer from pathogenic staphylococcus aureus . SNAP output
|
|
6fyx
|
ribosome |
cryo-EM (3.5 Å) |
Llacer JL, Hussain T, Saini AK, Nanda JD, Kaur S,
Gordiyenko Y, Kumar R, Hinnebusch AG, Lorsch JR,
Ramakrishnan V |
(2018) "Translational
initiation factor eIF5 replaces eIF1 on the 40S
ribosomal subunit to promote start-codon
recognition." Elife, 7.
doi: 10.7554/eLife.39273.
|
Structure of a partial yeast 48s preinitiation complex
with eif5 n-terminal domain (model c1) . SNAP output
|
|
6fyy
|
ribosome |
cryo-EM (3.02 Å) |
Llacer JL, Hussain T, Saini AK, Nanda JD, Kaur S,
Gordiyenko Y, Kumar R, Hinnebusch AG, Lorsch JR,
Ramakrishnan V |
(2018) "Translational
initiation factor eIF5 replaces eIF1 on the 40S
ribosomal subunit to promote start-codon
recognition." Elife, 7.
doi: 10.7554/eLife.39273.
|
Structure of a partial yeast 48s preinitiation complex
with eif5 n-terminal domain (model c2) . SNAP output
|
|
6g18
|
ribosome |
cryo-EM (3.6 Å) |
Ameismeier M, Cheng J, Berninghausen O, Beckmann
R |
(2018) "Visualizing
late states of human 40S ribosomal subunit
maturation." Nature, 558,
249-253. doi: 10.1038/s41586-018-0193-0.
|
cryo-EM structure of a late human pre-40s ribosomal
subunit - state c . SNAP
output
|
|
6g19
|
immune system |
cryo-EM (3.68 Å) |
Yu Q, Qu K, Modis Y |
(2018) "Cryo-EM
Structures of MDA5-dsRNA Filaments at Different Stages
of ATP Hydrolysis." Mol. Cell,
72, 999-1012.e6. doi: 10.1016/j.molcel.2018.10.012.
|
Cryoem structure of the mda5-dsrna filament with
74-degree helical twist . SNAP output
|
|
6g1s
|
immune system |
cryo-EM (3.93 Å) |
Yu Q, Qu K, Modis Y |
(2018) "Cryo-EM
Structures of MDA5-dsRNA Filaments at Different Stages
of ATP Hydrolysis." Mol. Cell,
72, 999-1012.e6. doi: 10.1016/j.molcel.2018.10.012.
|
Cryoem structure of the mda5-dsrna filament with
87-degree helical twist . SNAP output
|
|
6g1x
|
immune system |
cryo-EM (3.93 Å) |
Yu Q, Qu K, Modis Y |
(2018) "Cryo-EM
Structures of MDA5-dsRNA Filaments at Different Stages
of ATP Hydrolysis." Mol. Cell,
72, 999-1012.e6. doi: 10.1016/j.molcel.2018.10.012.
|
Cryoem structure of the mda5-dsrna filament with
91-degree helical twist . SNAP output
|
|
6g2k
|
RNA binding protein |
X-ray (2.01 Å) |
Pabis M, Popowicz GM, Stehle R, Fernandez-Ramos D,
Asami S, Warner L, Garcia-Maurino SM, Schlundt A,
Martinez-Chantar ML, Diaz-Moreno I, Sattler M |
(2019) "HuR
biological function involves RRM3-mediated dimerization
and RNA binding by all three RRMs." Nucleic
Acids Res., 47, 1011-1029. doi:
10.1093/nar/gky1138.
|
Structure of hur rrm3 in complex with RNA (uuuuuu) .
SNAP output
|
|
6g5h
|
ribosome |
cryo-EM (3.6 Å) |
Ameismeier M, Cheng J, Berninghausen O, Beckmann
R |
(2018) "Visualizing
late states of human 40S ribosomal subunit
maturation." Nature, 558,
249-253. doi: 10.1038/s41586-018-0193-0.
|
cryo-EM structure of a late human pre-40s ribosomal
subunit - mature . SNAP
output
|
|
6g5i
|
ribosome |
cryo-EM (3.5 Å) |
Ameismeier M, Cheng J, Berninghausen O, Beckmann
R |
(2018) "Visualizing
late states of human 40S ribosomal subunit
maturation." Nature, 558,
249-253. doi: 10.1038/s41586-018-0193-0.
|
cryo-EM structure of a late human pre-40s ribosomal
subunit - state r . SNAP
output
|
|
6g63
|
RNA binding protein |
X-ray (3.95 Å) |
Bandyra KJ, Wandzik JM, Luisi BF |
(2018) "Substrate
Recognition and Autoinhibition in the Central
Ribonuclease RNase E." Mol. Cell,
72, 275-285.e4. doi: 10.1016/j.molcel.2018.08.039.
|
Rnase e in complex with srna rrpa . SNAP output
|
|
6g90
|
splicing |
cryo-EM (4.0 Å) |
Plaschka C, Lin PC, Charenton C, Nagai K |
(2018) "Prespliceosome
structure provides insights into spliceosome assembly
and regulation." Nature,
559, 419-422. doi: 10.1038/s41586-018-0323-8.
|
Prespliceosome structure provides insight into
spliceosome assembly and regulation (map a2) . SNAP output
|
|
6g99
|
RNA binding protein |
NMR |
Loughlin FE, Lukavsky PJ, Kazeeva T, Reber S, Hock
EM, Colombo M, Von Schroetter C, Pauli P, Clery A,
Muhlemann O, Polymenidou M, Ruepp MD, Allain FH |
(2019) "The
Solution Structure of FUS Bound to RNA Reveals a
Bipartite Mode of RNA Recognition with Both Sequence
and Shape Specificity." Mol. Cell,
73, 490-504.e6. doi: 10.1016/j.molcel.2018.11.012.
|
Solution structure of fus-znf bound to uggug . SNAP output
|
|
6gaw
|
ribosome |
cryo-EM (3.2 Å) |
Kummer E, Leibundgut M, Rackham O, Lee RG, Boehringer
D, Filipovska A, Ban N |
(2018) "Unique
features of mammalian mitochondrial translation
initiation revealed by cryo-EM." Nature,
560, 263-267. doi: 10.1038/s41586-018-0373-y.
|
Unique features of mammalian mitochondrial translation
initiation revealed by cryo-EM. this file contains the
complete 55s ribosome. . SNAP output
|
|
6gaz
|
ribosome |
cryo-EM (3.1 Å) |
Kummer E, Leibundgut M, Rackham O, Lee RG, Boehringer
D, Filipovska A, Ban N |
(2018) "Unique
features of mammalian mitochondrial translation
initiation revealed by cryo-EM." Nature,
560, 263-267. doi: 10.1038/s41586-018-0373-y.
|
Unique features of mammalian mitochondrial translation
initiation revealed by cryo-EM. this file contains the
28s ribosomal subunit. . SNAP output
|
|
6gb2
|
ribosome |
cryo-EM (3.2 Å) |
Kummer E, Leibundgut M, Rackham O, Lee RG, Boehringer
D, Filipovska A, Ban N |
(2018) "Unique
features of mammalian mitochondrial translation
initiation revealed by cryo-EM." Nature,
560, 263-267. doi: 10.1038/s41586-018-0373-y.
|
Unique features of mammalian mitochondrial translation
initiation revealed by cryo-EM. this file contains the
39s ribosomal subunit. . SNAP output
|
|
6gbm
|
RNA binding protein |
NMR |
Loughlin FE, Lukavsky PJ, Kazeeva T, Reber S, Hock
EM, Colombo M, Von Schroetter C, Pauli P, Clery A,
Muhlemann O, Polymenidou M, Ruepp MD, Allain FH |
(2019) "The
Solution Structure of FUS Bound to RNA Reveals a
Bipartite Mode of RNA Recognition with Both Sequence
and Shape Specificity." Mol. Cell,
73, 490-504.e6. doi: 10.1016/j.molcel.2018.11.012.
|
Solution structure of fus-rrm bound to stem-loop RNA .
SNAP output
|
|
6gbz
|
ribosome |
cryo-EM (3.8 Å) |
Nikolay R, Hilal T, Qin B, Mielke T, Burger J, Loerke
J, Textoris-Taube K, Nierhaus KH, Spahn CMT |
(2018) "Structural
Visualization of the Formation and Activation of the
50S Ribosomal Subunit during In Vitro
Reconstitution." Mol. Cell,
70, 881-893.e3. doi: 10.1016/j.molcel.2018.05.003.
|
50s ribosomal subunit assembly intermediate state 5 .
SNAP output
|
|
6gc0
|
ribosome |
cryo-EM (3.8 Å) |
Nikolay R, Hilal T, Qin B, Mielke T, Burger J, Loerke
J, Textoris-Taube K, Nierhaus KH, Spahn CMT |
(2018) "Structural
Visualization of the Formation and Activation of the
50S Ribosomal Subunit during In Vitro
Reconstitution." Mol. Cell,
70, 881-893.e3. doi: 10.1016/j.molcel.2018.05.003.
|
50s ribosomal subunit assembly intermediate state 4 .
SNAP output
|
|
6gc4
|
ribosome |
cryo-EM (4.3 Å) |
Nikolay R, Hilal T, Qin B, Mielke T, Burger J, Loerke
J, Textoris-Taube K, Nierhaus KH, Spahn CMT |
(2018) "Structural
Visualization of the Formation and Activation of the
50S Ribosomal Subunit during In Vitro
Reconstitution." Mol. Cell,
70, 881-893.e3. doi: 10.1016/j.molcel.2018.05.003.
|
50s ribosomal subunit assembly intermediate state 3 .
SNAP output
|
|
6gc5
|
RNA binding protein |
X-ray (1.9 Å) |
Ripin N, Boudet J, Duszczyk MM, Hinniger A, Faller M,
Krepl M, Gadi A, Schneider RJ, Sponer J, Meisner-Kober
NC, Allain FH |
(2019) "Molecular
basis for AU-rich element recognition and dimerization
by the HuR C-terminal RRM." Proc. Natl. Acad.
Sci. U.S.A., 116, 2935-2944. doi:
10.1073/pnas.1808696116.
|
Molecular basis for au-rich element recognition and
dimerization by the hur c-terminal rrm . SNAP output
|
|
6gc6
|
ribosome |
cryo-EM (4.3 Å) |
Nikolay R, Hilal T, Qin B, Mielke T, Burger J, Loerke
J, Textoris-Taube K, Nierhaus KH, Spahn CMT |
(2018) "Structural
Visualization of the Formation and Activation of the
50S Ribosomal Subunit during In Vitro
Reconstitution." Mol. Cell,
70, 881-893.e3. doi: 10.1016/j.molcel.2018.05.003.
|
50s ribosomal subunit assembly intermediate state 2 .
SNAP output
|
|
6gc7
|
ribosome |
cryo-EM (4.3 Å) |
Nikolay R, Hilal T, Qin B, Mielke T, Burger J, Loerke
J, Textoris-Taube K, Nierhaus KH, Spahn CMT |
(2018) "Structural
Visualization of the Formation and Activation of the
50S Ribosomal Subunit during In Vitro
Reconstitution." Mol. Cell,
70, 881-893.e3. doi: 10.1016/j.molcel.2018.05.003.
|
50s ribosomal subunit assembly intermediate state 1 .
SNAP output
|
|
6gc8
|
ribosome |
cryo-EM (3.8 Å) |
Nikolay R, Hilal T, Qin B, Mielke T, Burger J, Loerke
J, Textoris-Taube K, Nierhaus KH, Spahn CMT |
(2018) "Structural
Visualization of the Formation and Activation of the
50S Ribosomal Subunit during In Vitro
Reconstitution." Mol. Cell,
70, 881-893.e3. doi: 10.1016/j.molcel.2018.05.003.
|
50s ribosomal subunit assembly intermediate - 50s rec*
. SNAP output
|
|
6gd2
|
RNA binding protein |
X-ray (1.9 Å) |
Pabis M, Popowicz GM, Stehle R, Fernandez-Ramos D,
Asami S, Warner L, Garcia-Maurino SM, Schlundt A,
Martinez-Chantar ML, Diaz-Moreno I, Sattler M |
(2019) "HuR
biological function involves RRM3-mediated dimerization
and RNA binding by all three RRMs." Nucleic
Acids Res., 47, 1011-1029. doi:
10.1093/nar/gky1138.
|
Structure of hur rrm3 in complex with RNA . SNAP output
|
|
6gd3
|
RNA binding protein |
X-ray (1.35 Å) |
Pabis M, Popowicz GM, Stehle R, Fernandez-Ramos D,
Asami S, Warner L, Garcia-Maurino SM, Schlundt A,
Martinez-Chantar ML, Diaz-Moreno I, Sattler M |
(2019) "HuR
biological function involves RRM3-mediated dimerization
and RNA binding by all three RRMs." Nucleic
Acids Res., 47, 1011-1029. doi:
10.1093/nar/gky1138.
|
Structure of hur rrm3 in complex with RNA (uauuua) .
SNAP output
|
|
6gjz
|
immune system |
cryo-EM (4.06 Å) |
Yu Q, Qu K, Modis Y |
(2018) "Cryo-EM
Structures of MDA5-dsRNA Filaments at Different Stages
of ATP Hydrolysis." Mol. Cell,
72, 999-1012.e6. doi: 10.1016/j.molcel.2018.10.012.
|
Cryoem structure of the mda5-dsrna filament in complex
with amppnp . SNAP
output
|
|
6gkh
|
immune system |
cryo-EM (4.06 Å) |
Yu Q, Qu K, Modis Y |
(2018) "Cryo-EM
Structures of MDA5-dsRNA Filaments at Different Stages
of ATP Hydrolysis." Mol. Cell,
72, 999-1012.e6. doi: 10.1016/j.molcel.2018.10.012.
|
Cryoem structure of the mda5-dsrna filament in complex
with adp-alf4 . SNAP
output
|
|
6gkm
|
immune system |
cryo-EM (3.87 Å) |
Yu Q, Qu K, Modis Y |
(2018) "Cryo-EM
Structures of MDA5-dsRNA Filaments at Different Stages
of ATP Hydrolysis." Mol. Cell,
72, 999-1012.e6. doi: 10.1016/j.molcel.2018.10.012.
|
Cryoem structure of the mda5-dsrna filament in complex
with atp (10 mm) . SNAP
output
|
|
6gpg
|
antiviral protein |
X-ray (2.894 Å) |
Lassig C, Lammens K, Gorenflos Lopez JL, Michalski S,
Fettscher O, Hopfner KP |
(2018) "Unified
mechanisms for self-RNA recognition by RIG-I
Singleton-Merten syndrome variants."
Elife, 7. doi: 10.7554/eLife.38958.
|
Structure of the rig-i singleton-merten syndrome
variant c268f . SNAP
output
|
|
6gq1
|
ribosome |
cryo-EM (4.4 Å) |
Pellegrino S, Demeshkina N, Mancera-Martinez E,
Melnikov S, Simonetti A, Myasnikov A, Yusupov M, Yusupova
G, Hashem Y |
(2018) "Structural
Insights into the Role of Diphthamide on Elongation
Factor 2 in mRNA Reading-Frame Maintenance." J.
Mol. Biol., 430, 2677-2687. doi:
10.1016/j.jmb.2018.06.006.
|
cryo-EM reconstruction of yeast 80s ribosome in complex
with mrna, trna and eef2 (gmppcp-sordarin) . SNAP output
|
|
6gqb
|
ribosome |
cryo-EM (3.9 Å) |
Pellegrino S, Demeshkina N, Mancera-Martinez E,
Melnikov S, Simonetti A, Myasnikov A, Yusupov M, Yusupova
G, Hashem Y |
(2018) "Structural
Insights into the Role of Diphthamide on Elongation
Factor 2 in mRNA Reading-Frame Maintenance." J.
Mol. Biol., 430, 2677-2687. doi:
10.1016/j.jmb.2018.06.006.
|
cryo-EM reconstruction of yeast 80s ribosome in complex
with mrna, trna and eef2 (gdp+alf4-sordarin) . SNAP output
|
|
6gqv
|
ribosome |
cryo-EM (4.0 Å) |
Pellegrino S, Demeshkina N, Mancera-Martinez E,
Melnikov S, Simonetti A, Myasnikov A, Yusupov M, Yusupova
G, Hashem Y |
(2018) "Structural
Insights into the Role of Diphthamide on Elongation
Factor 2 in mRNA Reading-Frame Maintenance." J.
Mol. Biol., 430, 2677-2687. doi:
10.1016/j.jmb.2018.06.006.
|
cryo-EM recosntruction of yeast 80s ribosome in complex
with mrna, trna and eef2 (gmppcp) . SNAP output
|
|
6gsj
|
ribosome |
X-ray (2.96 Å) |
Rozov A, Wolff P, Grosjean H, Yusupov M, Yusupova G,
Westhof E |
(2018) "Tautomeric
G•U pairs within the molecular ribosomal grip and
fidelity of decoding in bacteria." Nucleic
Acids Res., 46, 7425-7435. doi:
10.1093/nar/gky547.
|
Structure of t. thermophilus 70s ribosome complex with
mrna, trnafmet and cognate trnathr in the a-site .
SNAP output
|
|
6gsk
|
ribosome |
X-ray (3.36 Å) |
Rozov A, Wolff P, Grosjean H, Yusupov M, Yusupova G,
Westhof E |
(2018) "Tautomeric
G•U pairs within the molecular ribosomal grip and
fidelity of decoding in bacteria." Nucleic
Acids Res., 46, 7425-7435. doi:
10.1093/nar/gky547.
|
Structure of t. thermophilus 70s ribosome complex with
mrna, trnafmet and near-cognate trnathr in the a-site .
SNAP output
|
|
6gsl
|
ribosome |
X-ray (3.16 Å) |
Rozov A, Wolff P, Grosjean H, Yusupov M, Yusupova G,
Westhof E |
(2018) "Tautomeric
G•U pairs within the molecular ribosomal grip and
fidelity of decoding in bacteria." Nucleic
Acids Res., 46, 7425-7435. doi:
10.1093/nar/gky547.
|
Structure of t. thermophilus 70s ribosome complex with
mrna, trnafmet and cognate trnaarg in the a-site .
SNAP output
|
|
6gsm
|
ribosome |
cryo-EM (5.15 Å) |
Llacer JL, Hussain T, Dong J, Villamayor L,
Gordiyenko Y, Hinnebusch AG |
(2021) "Large-scale
movement of eIF3 domains during translation initiation
modulate start codon selection." Nucleic Acids
Res. doi: 10.1093/nar/gkab908.
|
Structure of a partial yeast 48s preinitiation complex
in open conformation. . SNAP output
|
|
6gsn
|
ribosome |
cryo-EM (5.75 Å) |
Llacer JL, Hussain T, Dong J, Villamayor L,
Gordiyenko Y, Hinnebusch AG |
(2021) "Large-scale
movement of eIF3 domains during translation initiation
modulate start codon selection." Nucleic Acids
Res. doi: 10.1093/nar/gkab908.
|
Structure of a partial yeast 48s preinitiation complex
in closed conformation . SNAP output
|
|
6gv4
|
virus |
cryo-EM (2.8 Å) |
Domanska A, Flatt JW, Jukonen JJJ, Geraets JA,
Butcher SJ |
(2019) "A
2.8-Angstrom-Resolution Cryo-Electron Microscopy
Structure of Human Parechovirus 3 in Complex with Fab
from a Neutralizing Antibody." J.Virol.,
93. doi: 10.1128/JVI.01597-18.
|
High-resolution cryo-EM of fab-labeled human
parechovirus 3 . SNAP
output
|
|
6gvy
|
viral protein |
X-ray (2.2 Å) |
de la Higuera I, Ferrer-Orta C, Moreno E, de Avila
AI, Soria ME, Singh K, Caridi F, Sobrino F, Sarafianos
SG, Perales C, Verdaguer N, Domingo E |
(2018) "Contribution
of a Multifunctional Polymerase Region of
Foot-and-Mouth Disease Virus to Lethal
Mutagenesis." J. Virol.,
92. doi: 10.1128/JVI.01119-18.
|
Mutant m16a of RNA dependent RNA polymerase 3d from
foot-and-mouth disease virus complexed with an template
-primer RNA . SNAP
output
|
|
6gwt
|
ribosome |
cryo-EM (3.8 Å) |
Graf M, Huter P, Maracci C, Peterek M, Rodnina MV,
Wilson DN |
(2018) "Visualization
of translation termination intermediates trapped by the
Apidaecin 137 peptide during RF3-mediated recycling of
RF1." Nat Commun, 9,
3053. doi: 10.1038/s41467-018-05465-1.
|
cryo-EM structure of an e. coli 70s ribosome in complex
with rf3-gdpcp, rf1(gaq) and pint-trna (state i) .
SNAP output
|
|
6gx6
|
RNA binding protein |
X-ray (2.0 Å) |
Jia M, Gut H, Chao JA |
(2018) "Structural
basis of IMP3 RRM12 recognition of RNA."
RNA, 24, 1659-1666. doi:
10.1261/rna.065649.118.
|
Crystal structure of imp3 rrm12 in complex with RNA
(acac) . SNAP output
|
|
6gxm
|
ribosome |
cryo-EM (3.8 Å) |
Graf M, Huter P, Maracci C, Peterek M, Rodnina MV,
Wilson DN |
(2018) "Visualization
of translation termination intermediates trapped by the
Apidaecin 137 peptide during RF3-mediated recycling of
RF1." Nat Commun, 9,
3053. doi: 10.1038/s41467-018-05465-1.
|
cryo-EM structure of an e. coli 70s ribosome in complex
with rf3-gdpcp, rf1(gaq) and pint-trna (state ii) .
SNAP output
|
|
6gxn
|
ribosome |
cryo-EM (3.9 Å) |
Graf M, Huter P, Maracci C, Peterek M, Rodnina MV,
Wilson DN |
(2018) "Visualization
of translation termination intermediates trapped by the
Apidaecin 137 peptide during RF3-mediated recycling of
RF1." Nat Commun, 9,
3053. doi: 10.1038/s41467-018-05465-1.
|
cryo-EM structure of an e. coli 70s ribosome in complex
with rf3-gdpcp, rf1(gaq) and pint-trna (state iii) .
SNAP output
|
|
6gxo
|
ribosome |
cryo-EM (3.9 Å) |
Graf M, Huter P, Maracci C, Peterek M, Rodnina MV,
Wilson DN |
(2018) "Visualization
of translation termination intermediates trapped by the
Apidaecin 137 peptide during RF3-mediated recycling of
RF1." Nat Commun, 9,
3053. doi: 10.1038/s41467-018-05465-1.
|
cryo-EM structure of a rotated e. coli 70s ribosome in
complex with rf3-gdpcp, rf1(gaq) and p-e-trna (state
iv) . SNAP output
|
|
6gxp
|
ribosome |
cryo-EM (4.4 Å) |
Graf M, Huter P, Maracci C, Peterek M, Rodnina MV,
Wilson DN |
(2018) "Visualization
of translation termination intermediates trapped by the
Apidaecin 137 peptide during RF3-mediated recycling of
RF1." Nat Commun, 9,
3053. doi: 10.1038/s41467-018-05465-1.
|
cryo-EM structure of a rotated e. coli 70s ribosome in
complex with rf3-gdpcp(rf3-only) . SNAP output
|
|
6gz3
|
ribosome |
cryo-EM (3.6 Å) |
Flis J, Holm M, Rundlet EJ, Loerke J, Hilal T,
Dabrowski M, Burger J, Mielke T, Blanchard SC, Spahn CMT,
Budkevich TV |
(2018) "tRNA
Translocation by the Eukaryotic 80S Ribosome and the
Impact of GTP Hydrolysis." Cell Rep,
25, 2676-2688.e7. doi: 10.1016/j.celrep.2018.11.040.
|
Trna translocation by the eukaryotic 80s ribosome and
the impact of gtp hydrolysis,
translocation-intermediate-post-1 (ti-post-1) .
SNAP output
|
|
6gz4
|
ribosome |
cryo-EM (3.6 Å) |
Flis J, Holm M, Rundlet EJ, Loerke J, Hilal T,
Dabrowski M, Burger J, Mielke T, Blanchard SC, Spahn CMT,
Budkevich TV |
(2018) "tRNA
Translocation by the Eukaryotic 80S Ribosome and the
Impact of GTP Hydrolysis." Cell Rep,
25, 2676-2688.e7. doi: 10.1016/j.celrep.2018.11.040.
|
Trna translocation by the eukaryotic 80s ribosome and
the impact of gtp hydrolysis,
translocation-intermediate-post-2 (ti-post-2) .
SNAP output
|
|
6gz5
|
ribosome |
cryo-EM (3.5 Å) |
Flis J, Holm M, Rundlet EJ, Loerke J, Hilal T,
Dabrowski M, Burger J, Mielke T, Blanchard SC, Spahn CMT,
Budkevich TV |
(2018) "tRNA
Translocation by the Eukaryotic 80S Ribosome and the
Impact of GTP Hydrolysis." Cell Rep,
25, 2676-2688.e7. doi: 10.1016/j.celrep.2018.11.040.
|
Trna translocation by the eukaryotic 80s ribosome and
the impact of gtp hydrolysis,
translocation-intermediate-post-3 (ti-post-3) .
SNAP output
|
|
6gzq
|
ribosome |
cryo-EM (3.28 Å) |
Flygaard RK, Boegholm N, Yusupov M, Jenner LB |
(2018) "Cryo-EM
structure of the hibernating Thermus thermophilus 100S
ribosome reveals a protein-mediated dimerization
mechanism." Nat Commun,
9, 4179. doi: 10.1038/s41467-018-06724-x.
|
T. thermophilus hibernating 70s ribosome . SNAP output
|
|
6gzx
|
ribosome |
cryo-EM (4.57 Å) |
Flygaard RK, Boegholm N, Yusupov M, Jenner LB |
(2018) "Cryo-EM
structure of the hibernating Thermus thermophilus 100S
ribosome reveals a protein-mediated dimerization
mechanism." Nat Commun,
9, 4179. doi: 10.1038/s41467-018-06724-x.
|
T. thermophilus hibernating 100s ribosome (ice) .
SNAP output
|
|
6gzz
|
ribosome |
cryo-EM (4.13 Å) |
Flygaard RK, Boegholm N, Yusupov M, Jenner LB |
(2018) "Cryo-EM
structure of the hibernating Thermus thermophilus 100S
ribosome reveals a protein-mediated dimerization
mechanism." Nat Commun,
9, 4179. doi: 10.1038/s41467-018-06724-x.
|
T. thermophilus hibernating 100s ribosome (amc) .
SNAP output
|
|
6h25
|
RNA binding protein |
cryo-EM (3.8 Å) |
Gerlach P, Schuller JM, Bonneau F, Basquin J,
Reichelt P, Falk S, Conti E |
(2018) "Distinct
and evolutionary conserved structural features of the
human nuclear exosome complex." Elife,
7. doi: 10.7554/eLife.38686.
|
Human nuclear RNA exosome exo-10-mpp6 complex .
SNAP output
|
|
6h4n
|
ribosome |
cryo-EM (3.0 Å) |
Beckert B, Turk M, Czech A, Berninghausen O, Beckmann
R, Ignatova Z, Plitzko JM, Wilson DN |
(2018) "Structure
of a hibernating 100S ribosome reveals an inactive
conformation of the ribosomal protein S1." Nat
Microbiol, 3, 1115-1121. doi:
10.1038/s41564-018-0237-0.
|
Structure of a hibernating 100s ribosome reveals an
inactive conformation of the ribosomal protein s1 - 70s
hibernating e. coli ribosome . SNAP output
|
|
6h58
|
ribosome |
cryo-EM (7.9 Å) |
Beckert B, Turk M, Czech A, Berninghausen O, Beckmann
R, Ignatova Z, Plitzko JM, Wilson DN |
(2018) "Structure
of a hibernating 100S ribosome reveals an inactive
conformation of the ribosomal protein S1." Nat
Microbiol, 3, 1115-1121. doi:
10.1038/s41564-018-0237-0.
|
Structure of a hibernating 100s ribosome reveals an
inactive conformation of the ribosomal protein s1 -
full 100s hibernating e. coli ribosome . SNAP output
|
|
6h5q
|
viral protein |
cryo-EM (3.3 Å) |
Desfosses A, Milles S, Jensen MR, Guseva S, Colletier
JP, Maurin D, Schoehn G, Gutsche I, Ruigrok RWH,
Blackledge M |
(2019) "Assembly
and cryo-EM structures of RNA-specific measles virus
nucleocapsids provide mechanistic insight into
paramyxoviral replication."
Proc.Natl.Acad.Sci.USA, 116,
4256-4264. doi: 10.1073/pnas.1816417116.
|
cryo-EM structure of in vitro assembled measles virus n
into nucleocapsid-like particles (nclps) bound to polya
RNA hexamers. . SNAP
output
|
|
6h5s
|
viral protein |
cryo-EM (3.3 Å) |
Desfosses A, Milles S, Jensen MR, Guseva S, Colletier
JP, Maurin D, Schoehn G, Gutsche I, Ruigrok RWH,
Blackledge M |
(2019) "Assembly
and cryo-EM structures of RNA-specific measles virus
nucleocapsids provide mechanistic insight into
paramyxoviral replication."
Proc.Natl.Acad.Sci.USA, 116,
4256-4264. doi: 10.1073/pnas.1816417116.
|
cryo-EM map of in vitro assembled measles virus n into
nucleocapsid-like particles (nclps) bound to viral
genomic 5-prime RNA hexamers. . SNAP output
|
|
6h61
|
immune system |
cryo-EM (4.02 Å) |
Yu Q, Qu K, Modis Y |
(2018) "Cryo-EM
Structures of MDA5-dsRNA Filaments at Different Stages
of ATP Hydrolysis." Mol. Cell,
72, 999-1012.e6. doi: 10.1016/j.molcel.2018.10.012.
|
Cryoem structure of the mda5-dsrna filament with 89
degree twist and without nucleotide . SNAP output
|
|
6h66
|
immune system |
cryo-EM (4.16 Å) |
Yu Q, Qu K, Modis Y |
(2018) "Cryo-EM
Structures of MDA5-dsRNA Filaments at Different Stages
of ATP Hydrolysis." Mol. Cell,
72, 999-1012.e6. doi: 10.1016/j.molcel.2018.10.012.
|
Cryoem structure of the mda5-dsrna filament with 93
degree twist and without nucleotide . SNAP output
|
|
6h9h
|
RNA binding protein |
X-ray (1.75 Å) |
Ozcan A, Pausch P, Linden A, Wulf A, Schuhle K,
Heider J, Urlaub H, Heimerl T, Bange G, Randau L |
(2019) "Type IV
CRISPR RNA processing and effector complex formation in
Aromatoleum aromaticum." Nat Microbiol,
4, 89-96. doi: 10.1038/s41564-018-0274-8.
|
Csf5, crispr-cas type iv cas6 crrna endonuclease .
SNAP output
|
|
6h9i
|
RNA binding protein |
X-ray (2.29 Å) |
Ozcan A, Pausch P, Linden A, Wulf A, Schuhle K,
Heider J, Urlaub H, Heimerl T, Bange G, Randau L |
(2019) "Type IV
CRISPR RNA processing and effector complex formation in
Aromatoleum aromaticum." Nat Microbiol,
4, 89-96. doi: 10.1038/s41564-018-0274-8.
|
Csf5, crispr-cas type iv cas6 crrna endonuclease .
SNAP output
|
|
6ha1
|
ribosome |
cryo-EM (3.1 Å) |
Crowe-McAuliffe C, Graf M, Huter P, Takada H,
Abdelshahid M, Novacek J, Murina V, Atkinson GC,
Hauryliuk V, Wilson DN |
(2018) "Structural
basis for antibiotic resistance mediated by theBacillus
subtilisABCF ATPase VmlR." Proc. Natl. Acad.
Sci. U.S.A., 115, 8978-8983. doi:
10.1073/pnas.1808535115.
|
cryo-EM structure of a 70s bacillus subtilis ribosome
translating the ermd leader peptide in complex with
telithromycin . SNAP
output
|
|
6ha8
|
ribosome |
cryo-EM (3.5 Å) |
Crowe-McAuliffe C, Graf M, Huter P, Takada H,
Abdelshahid M, Novacek J, Murina V, Atkinson GC,
Hauryliuk V, Wilson DN |
(2018) "Structural
basis for antibiotic resistance mediated by theBacillus
subtilisABCF ATPase VmlR." Proc. Natl. Acad.
Sci. U.S.A., 115, 8978-8983. doi:
10.1073/pnas.1808535115.
|
cryo-EM structure of the abcf protein vmlr bound to the
bacillus subtilis ribosome . SNAP output
|
|
6hak
|
transcription |
X-ray (3.95 Å) |
Das K, Martinez SE, DeStefano JJ, Arnold E |
(2019) "Structure
of HIV-1 RT/dsRNA initiation complex prior to
nucleotide incorporation."
Proc.Natl.Acad.Sci.USA, 116,
7308-7313. doi: 10.1073/pnas.1814170116.
|
Crystal structure of hiv-1 reverse transcriptase (rt)
in complex with a double stranded RNA represents the rt
transcription initiation complex prior to nucleotide
incorporation . SNAP
output
|
|
6hau
|
RNA binding protein |
X-ray (1.86 Å) |
Tunnicliffe RB, Levy C, Ruiz Nivia HD, Sandri-Goldin
RM, Golovanov AP |
(2019) "Structural
identification of conserved RNA binding sites in
herpesvirus ORF57 homologs: implications for PAN RNA
recognition." Nucleic Acids Res.,
47, 1987-2001. doi: 10.1093/nar/gky1181.
|
Kshv pan RNA mta-response element fragment complexed
with the globular domain of herpesvirus saimiri orf57 .
SNAP output
|
|
6hct
|
RNA |
X-ray (3.091 Å) |
Huang L, Ashraf S, Lilley DMJ |
(2019) "The role
of RNA structure in translational regulation by L7Ae
protein in archaea." RNA,
25, 60-69. doi: 10.1261/rna.068510.118.
|
Crystal structure of archeoglobus fulgidus l7ae bound
to its cognate utr k-turn . SNAP output
|
|
6hd7
|
translation |
cryo-EM (3.4 Å) |
Knorr AG, Schmidt C, Tesina P, Berninghausen O,
Becker T, Beatrix B, Beckmann R |
(2019) "Ribosome-NatA
architecture reveals that rRNA expansion segments
coordinate N-terminal acetylation." Nat.
Struct. Mol. Biol., 26, 35-39.
doi: 10.1038/s41594-018-0165-y.
|
cryo-EM structure of the ribosome-nata complex .
SNAP output
|
|
6hhq
|
ribosome |
X-ray (3.1 Å) |
Pellegrino S, Meyer M, Konst ZA, Holm M, Voora VK,
Kashinskaya D, Zanette C, Mobley DL, Yusupova G,
Vanderwal CD, Blanchard SC, Yusupov M |
(2019) "Understanding
the role of intermolecular interactions between
lissoclimides and the eukaryotic ribosome."
Nucleic Acids Res., 47,
3223-3232. doi: 10.1093/nar/gkz053.
|
Crystal structure of compound c45 bound to the yeast
80s ribosome . SNAP
output
|
|
6hiv
|
ribosome |
cryo-EM (7.8 Å) |
Ramrath DJF, Niemann M, Leibundgut M, Bieri P, Prange
C, Horn EK, Leitner A, Boehringer D, Schneider A, Ban
N |
(2018) "Evolutionary
shift toward protein-based architecture in trypanosomal
mitochondrial ribosomes." Science,
362. doi: 10.1126/science.aau7735.
|
cryo-EM structure of the trypanosoma brucei
mitochondrial ribosome - this entry contains the
complete mitoribosome . SNAP output
|
|
6hiw
|
ribosome |
cryo-EM (3.37 Å) |
Ramrath DJF, Niemann M, Leibundgut M, Bieri P, Prange
C, Horn EK, Leitner A, Boehringer D, Schneider A, Ban
N |
(2018) "Evolutionary
shift toward protein-based architecture in trypanosomal
mitochondrial ribosomes." Science,
362. doi: 10.1126/science.aau7735.
|
cryo-EM structure of the trypanosoma brucei
mitochondrial ribosome - this entry contains the
complete small mitoribosomal subunit in complex with
mt-if-3 . SNAP
output
|
|
6hix
|
ribosome |
cryo-EM (3.39 Å) |
Ramrath DJF, Niemann M, Leibundgut M, Bieri P, Prange
C, Horn EK, Leitner A, Boehringer D, Schneider A, Ban
N |
(2018) "Evolutionary
shift toward protein-based architecture in trypanosomal
mitochondrial ribosomes." Science,
362. doi: 10.1126/science.aau7735.
|
cryo-EM structure of the trypanosoma brucei
mitochondrial ribosome - this entry contains the large
mitoribosomal subunit . SNAP output
|
|
6hiy
|
ribosome |
cryo-EM (3.27 Å) |
Ramrath DJF, Niemann M, Leibundgut M, Bieri P, Prange
C, Horn EK, Leitner A, Boehringer D, Schneider A, Ban
N |
(2018) "Evolutionary
shift toward protein-based architecture in trypanosomal
mitochondrial ribosomes." Science,
362. doi: 10.1126/science.aau7735.
|
cryo-EM structure of the trypanosoma brucei
mitochondrial ribosome - this entry contains the body
of the small mitoribosomal subunit in complex with
mt-if-3 . SNAP
output
|
|
6hiz
|
ribosome |
cryo-EM (3.08 Å) |
Ramrath DJF, Niemann M, Leibundgut M, Bieri P, Prange
C, Horn EK, Leitner A, Boehringer D, Schneider A, Ban
N |
(2018) "Evolutionary
shift toward protein-based architecture in trypanosomal
mitochondrial ribosomes." Science,
362. doi: 10.1126/science.aau7735.
|
cryo-EM structure of the trypanosoma brucei
mitochondrial ribosome - this entry contains the head
of the small mitoribosomal subunit . SNAP output
|
|
6hma
|
ribosome |
cryo-EM (2.65 Å) |
Eyal Z, Cimicata G |
"Improved model derived from cryo-EM map of
Staphylococcus aureus large ribosomal subunit." |
Improved model derived from cryo-EM map of
staphylococcus aureus large ribosomal subunit .
SNAP output
|
|
6hpj
|
RNA binding protein |
NMR |
Clery A, Krepl M, Nguyen CKX, Moursy A, Jorjani H,
Katsantoni M, Okoniewski M, Mittal N, Zavolan M, Sponer
J, Allain FH |
(2021) "Structure
of SRSF1 RRM1 bound to RNA reveals an unexpected
bimodal mode of interaction and explains its
involvement in SMN1 exon7 splicing." Nat
Commun, 12, 428. doi: 10.1038/s41467-020-20481-w.
|
Structure of human srsf1 rrm1 bound to aacaaa RNA .
SNAP output
|
|
6hrm
|
ribosome |
cryo-EM (2.96 Å) |
Schmied WH, Tnimov Z, Uttamapinant C, Rae CD, Fried
SD, Chin JW |
(2018) "Controlling
orthogonal ribosome subunit interactions enables
evolution of new function." Nature,
564, 444-448. doi: 10.1038/s41586-018-0773-z.
|
E. coli 70s d2d8 stapled ribosome . SNAP output
|
|
6htq
|
ribosome |
cryo-EM (4.5 Å) |
Pausch P, Abdelshahid M, Steinchen W, Schafer H,
Gratani FL, Freibert SA, Wolz C, Turgay K, Wilson DN,
Bange G |
(2020) "Structural
Basis for Regulation of the Opposing (p)ppGpp
Synthetase and Hydrolase within the Stringent Response
Orchestrator Rel." Cell Rep,
32, 108157. doi: 10.1016/j.celrep.2020.108157.
|
Stringent response control by a bifunctional rela
enzyme in the presence and absence of the ribosome .
SNAP output
|
|
6htu
|
RNA binding protein |
X-ray (2.888 Å) |
Lazzaretti D, Bandholz-Cajamarca L, Emmerich C,
Schaaf K, Basquin C, Irion U, Bono F |
(2018) "The
crystal structure of Staufen1 in complex with a
physiological RNA sheds light on substrate
selectivity." Life Sci Alliance,
1, e201800187. doi: 10.26508/lsa.201800187.
|
Structure of hstau1 dsrbd3-4 in complex with arf1 RNA .
SNAP output
|
|
6hxx
|
virus |
cryo-EM (3.4 Å) |
Kezar A, Kavcic L, Polak M, Novacek J,
Gutierrez-Aguirre I, Znidaric MT, Coll A, Stare K, Gruden
K, Ravnikar M, Pahovnik D, Zagar E, Merzel F, Anderluh G,
Podobnik M |
(2019) "Structural
basis for the multitasking nature of the potato virus Y
coat protein." Sci Adv,
5, eaaw3808. doi: 10.1126/sciadv.aaw3808.
|
Potato virus y . SNAP
output
|
|
6i0t
|
transferase |
X-ray (2.0 Å) |
Kroupova A, Ivascu A, Reimao-Pinto MM, Ameres SL,
Jinek M |
(2019) "Structural
basis for acceptor RNA substrate selectivity of the 3'
terminal uridylyl transferase Tailor." Nucleic
Acids Res., 47, 1030-1042. doi:
10.1093/nar/gky1164.
|
Crystal structure of dmtailor in complex with gpu .
SNAP output
|
|
6i0u
|
transferase |
X-ray (2.001 Å) |
Kroupova A, Ivascu A, Reimao-Pinto MM, Ameres SL,
Jinek M |
(2019) "Structural
basis for acceptor RNA substrate selectivity of the 3'
terminal uridylyl transferase Tailor." Nucleic
Acids Res., 47, 1030-1042. doi:
10.1093/nar/gky1164.
|
Crystal structure of dmtailor in complex with u6 RNA .
SNAP output
|
|
6i0v
|
transferase |
X-ray (1.851 Å) |
Kroupova A, Ivascu A, Reimao-Pinto MM, Ameres SL,
Jinek M |
(2019) "Structural
basis for acceptor RNA substrate selectivity of the 3'
terminal uridylyl transferase Tailor." Nucleic
Acids Res., 47, 1030-1042. doi:
10.1093/nar/gky1164.
|
Crystal structure of dmtailor in complex with cacagu
RNA . SNAP output
|
|
6i0y
|
ribosome |
cryo-EM (3.2 Å) |
Tian P, Steward A, Kudva R, Su T, Shilling PJ,
Nickson AA, Hollins JJ, Beckmann R, von Heijne G, Clarke
J, Best RB |
(2018) "Folding
pathway of an Ig domain is conserved on and off the
ribosome." Proc. Natl. Acad. Sci. U.S.A.,
115, E11284-E11293. doi: 10.1073/pnas.1810523115.
|
Tnac-stalled ribosome complex with the titin i27 domain
folding close to the ribosomal exit tunnel . SNAP output
|
|
6i2n
|
viral protein |
cryo-EM (3.3 Å) |
Arragain B, Reguera J, Desfosses A, Gutsche I,
Schoehn G, Malet H |
(2019) "High
resolution cryo-EM structure of the helical RNA-bound
Hantaan virus nucleocapsid reveals its assembly
mechanisms." Elife, 8.
doi: 10.7554/eLife.43075.
|
Helical RNA-bound hantaan virus nucleocapsid . SNAP output
|
|
6i3p
|
hydrolase |
X-ray (2.75 Å) |
Hamann F, Enders M, Ficner R |
(2019) "Structural
basis for RNA translocation by DEAH-box ATPases."
Nucleic Acids Res., 47,
4349-4362. doi: 10.1093/nar/gkz150.
|
Crystal structure of deah-box atpase prp22 with bound
ssrna . SNAP output
|
|
6i7o
|
translation |
cryo-EM (5.3 Å) |
Ikeuchi K, Tesina P, Matsuo Y, Sugiyama T, Cheng J,
Saeki Y, Tanaka K, Becker T, Beckmann R, Inada T |
(2019) "Collided
ribosomes form a unique structural interface to induce
Hel2-driven quality control pathways." EMBO
J., 38. doi: 10.15252/embj.2018100276.
|
The structure of a di-ribosome (disome) as a unit for
rqc and ngd quality control pathways recognition. .
SNAP output
|
|
6i7v
|
ribosome |
X-ray (2.9 Å) |
Lilleorg S, Reier K, Pulk A, Liiv A, Tammsalu T, Peil
L, Cate JD, Remme J |
(2018) "Bacterial
ribosome heterogeneity: Changes in ribosomal protein
composition during transition into stationary growth
phase." Biochimie, 156,
169-180. doi: 10.1016/j.biochi.2018.10.013.
|
Ribosomal protein paralogs bl31 and bl36 . SNAP output
|
|
6i9r
|
ribosome |
cryo-EM (3.9 Å) |
Sighel D, Notarangelo M, Aibara S, Re A, Ricci G,
Guida M, Soldano A, Adami V, Ambrosini C, Broso F,
Rosatti EF, Longhi S, Buccarelli M, D'Alessandris QG,
Giannetti S, Pacioni S, Ricci-Vitiani L, Rorbach J,
Pallini R, Roulland S, Amunts A, Mancini I, Modelska A,
Quattrone A |
(2021) "Inhibition
of mitochondrial translation suppresses glioblastoma
stem cell growth." Cell Rep,
35, 109024. doi: 10.1016/j.celrep.2021.109024.
|
Large subunit of the human mitochondrial ribosome in
complex with virginiamycin m and quinupristin .
SNAP output
|
|
6icz
|
splicing |
cryo-EM (3.0 Å) |
Zhang X, Zhan X, Yan C, Zhang W, Liu D, Lei J, Shi
Y |
(2019) "Structures
of the human spliceosomes before and after release of
the ligated exon." Cell Res.,
29, 274-285. doi: 10.1038/s41422-019-0143-x.
|
cryo-EM structure of a human post-catalytic spliceosome
(p complex) at 3.0 angstrom . SNAP output
|
|
6id0
|
splicing |
cryo-EM (2.9 Å) |
Zhang X, Zhan X, Yan C, Zhang W, Liu D, Lei J, Shi
Y |
(2019) "Structures
of the human spliceosomes before and after release of
the ligated exon." Cell Res.,
29, 274-285. doi: 10.1038/s41422-019-0143-x.
|
cryo-EM structure of a human intron lariat spliceosome
prior to prp43 loaded (ils1 complex) at 2.9 angstrom
resolution . SNAP
output
|
|
6id1
|
splicing |
cryo-EM (2.86 Å) |
Zhang X, Zhan X, Yan C, Zhang W, Liu D, Lei J, Shi
Y |
(2019) "Structures
of the human spliceosomes before and after release of
the ligated exon." Cell Res.,
29, 274-285. doi: 10.1038/s41422-019-0143-x.
|
cryo-EM structure of a human intron lariat spliceosome
after prp43 loaded (ils2 complex) at 2.9 angstrom
resolution . SNAP
output
|
|
6ifk
|
RNA binding protein |
cryo-EM (3.2 Å) |
You L, Ma J, Wang J, Artamonova D, Wang M, Liu L,
Xiang H, Severinov K, Zhang X, Wang Y |
(2019) "Structure
Studies of the CRISPR-Csm Complex Reveal Mechanism of
Co-transcriptional Interference." Cell,
176, 239-253.e16. doi: 10.1016/j.cell.2018.10.052.
|
cryo-EM structure of type iii-a csm-ctr1 complex,
amppnp bound . SNAP
output
|
|
6ifl
|
RNA binding protein |
cryo-EM (3.16 Å) |
You L, Ma J, Wang J, Artamonova D, Wang M, Liu L,
Xiang H, Severinov K, Zhang X, Wang Y |
(2019) "Structure
Studies of the CRISPR-Csm Complex Reveal Mechanism of
Co-transcriptional Interference." Cell,
176, 239-253.e16. doi: 10.1016/j.cell.2018.10.052.
|
cryo-EM structure of type iii-a csm-ntr complex .
SNAP output
|
|
6ifn
|
RNA binding protein |
X-ray (2.9 Å) |
You L, Ma J, Wang J, Artamonova D, Wang M, Liu L,
Xiang H, Severinov K, Zhang X, Wang Y |
(2019) "Structure
Studies of the CRISPR-Csm Complex Reveal Mechanism of
Co-transcriptional Interference." Cell,
176, 239-253.e16. doi: 10.1016/j.cell.2018.10.052.
|
Crystal structure of type iii-a crispr csm complex .
SNAP output
|
|
6ifo
|
RNA binding protein-RNA |
X-ray (3.313 Å) |
Liu L, Yin M, Wang M, Wang Y |
(2019) "Phage
AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and
Anti-CRISPR Arms Race." Mol. Cell,
73, 611-620.e3. doi: 10.1016/j.molcel.2018.11.011.
|
Crystal structure of acriia2-spycas9-sgrna ternary
complex . SNAP
output
|
|
6ifr
|
RNA binding protein |
cryo-EM (3.4 Å) |
You L, Ma J, Wang J, Artamonova D, Wang M, Liu L,
Xiang H, Severinov K, Zhang X, Wang Y |
(2019) "Structure
Studies of the CRISPR-Csm Complex Reveal Mechanism of
Co-transcriptional Interference." Cell,
176, 239-253.e16. doi: 10.1016/j.cell.2018.10.052.
|
Type iii-a csm complex, cryo-EM structure of csm-ntr,
atp bound . SNAP
output
|
|
6ifu
|
RNA binding protein |
cryo-EM (3.05 Å) |
You L, Ma J, Wang J, Artamonova D, Wang M, Liu L,
Xiang H, Severinov K, Zhang X, Wang Y |
(2019) "Structure
Studies of the CRISPR-Csm Complex Reveal Mechanism of
Co-transcriptional Interference." Cell,
176, 239-253.e16. doi: 10.1016/j.cell.2018.10.052.
|
cryo-EM structure of type iii-a csm-ctr2-dsDNA complex
. SNAP output
|
|
6ify
|
RNA binding protein |
cryo-EM (3.8 Å) |
You L, Ma J, Wang J, Artamonova D, Wang M, Liu L,
Xiang H, Severinov K, Zhang X, Wang Y |
(2019) "Structure
Studies of the CRISPR-Csm Complex Reveal Mechanism of
Co-transcriptional Interference." Cell,
176, 239-253.e16. doi: 10.1016/j.cell.2018.10.052.
|
Type iii-a csm complex, cryo-EM structure of csm-ctr1 .
SNAP output
|
|
6ifz
|
RNA binding protein |
cryo-EM (3.58 Å) |
You L, Ma J, Wang J, Artamonova D, Wang M, Liu L,
Xiang H, Severinov K, Zhang X, Wang Y |
(2019) "Structure
Studies of the CRISPR-Csm Complex Reveal Mechanism of
Co-transcriptional Interference." Cell,
176, 239-253.e16. doi: 10.1016/j.cell.2018.10.052.
|
Type iii-a csm complex, cryo-EM structure of
csm-ctr2-ssDNA complex . SNAP output
|
|
6ig0
|
RNA binding protein |
cryo-EM (3.37 Å) |
You L, Ma J, Wang J, Artamonova D, Wang M, Liu L,
Xiang H, Severinov K, Zhang X, Wang Y |
(2019) "Structure
Studies of the CRISPR-Csm Complex Reveal Mechanism of
Co-transcriptional Interference." Cell,
176, 239-253.e16. doi: 10.1016/j.cell.2018.10.052.
|
Type iii-a csm complex, cryo-EM structure of csm-ctr1,
atp bound . SNAP
output
|
|
6ij2
|
hydrolase |
X-ray (1.7 Å) |
Yadav M, Pal K, Sen U |
(2019) "Structures
of c-di-GMP/cGAMP degrading phosphodiesterase VcEAL:
identification of a novel conformational switch and its
implication." Biochem.J.,
476, 3333-3353. doi: 10.1042/BCJ20190399.
|
Crystal structure of a standalone versatile eal protein
from vibrio cholerae o395 - 5'-pgpg bound form .
SNAP output
|
|
6iqw
|
RNA binding protein-RNA |
cryo-EM (3.35 Å) |
Huo Y, Li T, Wang N, Dong Q, Wang X, Jiang T |
(2018) "Cryo-EM
structure of Type III-A CRISPR effector complex."
Cell Res., 28, 1195-1197.
doi: 10.1038/s41422-018-0115-6.
|
cryo-EM structure of csm effector complex . SNAP output
|
|
6is0
|
transferase-RNA |
X-ray (1.8 Å) |
Akichika S, Hirano S, Shichino Y, Suzuki T, Nishimasu
H, Ishitani R, Sugita A, Hirose Y, Iwasaki S, Nureki O,
Suzuki T |
(2019) "Cap-specific
terminal N 6 -methylation of RNA by an RNA polymerase
II-associated methyltransferase." Science,
363. doi: 10.1126/science.aav0080.
|
Crystal structure of the zebrafish cap-specific
adenosine methyltransferase bound to sah and m7g-capped
RNA . SNAP output
|
|
6iv6
|
immune system-RNA |
cryo-EM (3.6 Å) |
Dong L, Guan X, Li N, Zhang F, Zhu Y, Ren K, Yu L,
Zhou F, Han Z, Gao N, Huang Z |
(2019) "An
anti-CRISPR protein disables type V Cas12a by
acetylation." Nat. Struct. Mol. Biol.,
26, 308-314. doi: 10.1038/s41594-019-0206-1.
|
cryo-EM structure of acrva5-acetylated mbcas12a in
complex with crrna . SNAP output
|
|
6iv8
|
RNA binding protein-RNA |
X-ray (2.15 Å) |
Zhang B, Ye Y, Ye W, Perculija V, Jiang H, Chen Y, Li
Y, Chen J, Lin J, Wang S, Chen Q, Han YS, Ouyang S |
(2019) "Two HEPN
domains dictate CRISPR RNA maturation and target
cleavage in Cas13d." Nat Commun,
10, 2544. doi: 10.1038/s41467-019-10507-3.
|
The selenomethionine(semet)-derived cas13d binary
complex . SNAP
output
|
|
6iv9
|
RNA binding protein-RNA |
X-ray (1.86 Å) |
Zhang B, Ye Y, Ye W, Perculija V, Jiang H, Chen Y, Li
Y, Chen J, Lin J, Wang S, Chen Q, Han YS, Ouyang S |
(2019) "Two HEPN
domains dictate CRISPR RNA maturation and target
cleavage in Cas13d." Nat Commun,
10, 2544. doi: 10.1038/s41467-019-10507-3.
|
The cas13d binary complex . SNAP output
|
|
6j6g
|
splicing |
cryo-EM (3.2 Å) |
Wan R, Bai R, Yan C, Lei J, Shi Y |
(2019) "Structures
of the Catalytically Activated Yeast Spliceosome Reveal
the Mechanism of Branching." Cell,
177, 339-351.e13. doi: 10.1016/j.cell.2019.02.006.
|
cryo-EM structure of the yeast b*-a2 complex at an
average resolution of 3.2 angstrom . SNAP output
|
|
6j6h
|
splicing |
cryo-EM (3.6 Å) |
Wan R, Bai R, Yan C, Lei J, Shi Y |
(2019) "Structures
of the Catalytically Activated Yeast Spliceosome Reveal
the Mechanism of Branching." Cell,
177, 339-351.e13. doi: 10.1016/j.cell.2019.02.006.
|
cryo-EM structure of the yeast b*-a1 complex at an
average resolution of 3.6 angstrom . SNAP output
|
|
6j6n
|
splicing |
cryo-EM (3.86 Å) |
Wan R, Bai R, Yan C, Lei J, Shi Y |
(2019) "Structures
of the Catalytically Activated Yeast Spliceosome Reveal
the Mechanism of Branching." Cell,
177, 339-351.e13. doi: 10.1016/j.cell.2019.02.006.
|
cryo-EM structure of the yeast b*-b1 complex at an
average resolution of 3.86 angstrom . SNAP output
|
|
6j6q
|
splicing |
cryo-EM (3.7 Å) |
Wan R, Bai R, Yan C, Lei J, Shi Y |
(2019) "Structures
of the Catalytically Activated Yeast Spliceosome Reveal
the Mechanism of Branching." Cell,
177, 339-351.e13. doi: 10.1016/j.cell.2019.02.006.
|
cryo-EM structure of the yeast b*-b2 complex at an
average resolution of 3.7 angstrom . SNAP output
|
|
6j7z
|
hydrolase |
X-ray (2.005 Å) |
Chu LY, Agrawal S, Chen YP, Yang WZ, Yuan HS |
(2019) "Structural
insights into nanoRNA degradation by human Rexo2."
Rna, 25, 737-746. doi:
10.1261/rna.070557.119.
|
Human mitochondrial oligoribonuclease in complex with
RNA . SNAP output
|
|
6jc3
|
nuclear protein-RNA |
cryo-EM (4.8 Å) |
Song X, Shan H, Zhu Y, Hu S, Xue L, Chen Y, Ding W,
Niu T, Gu J, Ouyang S, Shen QT, Liu ZJ |
(2019) "Self-capping
of nucleoprotein filaments protects the Newcastle
disease virus genome." Elife,
8. doi: 10.7554/eLife.45057.
|
The cryo-EM structure of nucleoprotein-RNA complex of
newcastle disease virus . SNAP output
|
|
6jdq
|
hydrolase-RNA |
X-ray (2.95 Å) |
Sun W, Yang J, Cheng Z, Amrani N, Liu C, Wang K,
Ibraheim R, Edraki A, Huang X, Wang M, Wang J, Liu L,
Sheng G, Yang Y, Lou J, Sontheimer EJ, Wang Y |
(2019) "Structures
of Neisseria meningitidis Cas9 Complexes in
Catalytically Poised and Anti-CRISPR-Inhibited
States." Mol.Cell, 76,
938. doi: 10.1016/j.molcel.2019.09.025.
|
Crystal structure of nme1cas9 in complex with sgrna .
SNAP output
|
|
6je9
|
hydrolase-hydrolase inhibitor-RNA |
X-ray (3.46 Å) |
Sun W, Yang J, Cheng Z, Amrani N, Liu C, Wang K,
Ibraheim R, Edraki A, Huang X, Wang M, Wang J, Liu L,
Sheng G, Yang Y, Lou J, Sontheimer EJ, Wang Y |
(2019) "Structures
of Neisseria meningitidis Cas9 Complexes in
Catalytically Poised and Anti-CRISPR-Inhibited
States." Mol.Cell, 76,
938. doi: 10.1016/j.molcel.2019.09.025.
|
Crystal structure of nme1cas9-sgrna dimer mediated by
double protein inhibitor acriic3 monomers . SNAP output
|
|
6jim
|
viral protein-RNA |
X-ray (2.0 Å) |
Law YS, Utt A, Tan YB, Zheng J, Wang S, Chen MW,
Griffin PR, Merits A, Luo D |
(2019) "Structural
insights into RNA recognition by the Chikungunya virus
nsP2 helicase." Proc.Natl.Acad.Sci.USA,
116, 9558-9567. doi: 10.1073/pnas.1900656116.
|
Viral helicase protein . SNAP output
|
|
6jvx
|
RNA binding protein-RNA |
X-ray (2.301 Å) |
Qian K, Li M, Wang J, Zhang M, Wang M |
(2020) "Structural
basis for mRNA recognition by human RBM38."
Biochem.J., 477, 161-172.
doi: 10.1042/BCJ20190652.
|
Crystal structure of rbm38 in complex with RNA .
SNAP output
|
|
6k0a
|
RNA binding protein-RNA |
cryo-EM (4.6 Å) |
Wan F, Wang Q, Tan J, Tan M, Chen J, Shi S, Lan P, Wu
J, Lei M |
(2019) "Cryo-electron
microscopy structure of an archaeal ribonuclease P
holoenzyme." Nat Commun,
10, 2617. doi: 10.1038/s41467-019-10496-3.
|
cryo-EM structure of an archaeal ribonuclease p .
SNAP output
|
|
6k0b
|
RNA binding protein-RNA |
cryo-EM (4.3 Å) |
Wan F, Wang Q, Tan J, Tan M, Chen J, Shi S, Lan P, Wu
J, Lei M |
(2019) "Cryo-electron
microscopy structure of an archaeal ribonuclease P
holoenzyme." Nat Commun,
10, 2617. doi: 10.1038/s41467-019-10496-3.
|
cryo-EM structure of archaeal ribonuclease p with
mature trna . SNAP
output
|
|
6k32
|
viral protein-RNA |
cryo-EM (3.2 Å) |
Li X, Wang L, Wang X, Chen W, Yang T, Song J, Liu H,
Cheng L |
(2020) "Structure
of RdRps Within a Transcribing dsRNA Virus Provides
Insights Into the Mechanisms of RNA Synthesis."
J.Mol.Biol., 432, 358-366.
doi: 10.1016/j.jmb.2019.09.015.
|
Rdrp complex . SNAP
output
|
|
6ke6
|
ribosome |
cryo-EM (3.4 Å) |
Du Y, An W, Qi S, Ye K |
"3.4 angstrom cryo-EM structure of yeast 90S small
subunit preribosome." |
3.4 angstrom cryo-EM structure of yeast 90s small
subunit preribosome . SNAP output
|
|
6kl9
|
RNA binding protein-RNA |
cryo-EM (3.25 Å) |
Peng R, Li Z, Xu Y, He S, Peng Q, Wu LA, Wu Y, Qi J,
Wang P, Shi Y, Gao GF |
(2019) "Structural
insight into multistage inhibition of CRISPR-Cas12a by
AcrVA4." Proc.Natl.Acad.Sci.USA,
116, 18928-18936. doi: 10.1073/pnas.1909400116.
|
Structure of lbcas12a-crrna complex bound to acrva4
(form a complex) . SNAP
output
|
|
6klb
|
RNA binding protein-RNA |
cryo-EM (4.1 Å) |
Peng R, Li Z, Xu Y, He S, Peng Q, Wu LA, Wu Y, Qi J,
Wang P, Shi Y, Gao GF |
(2019) "Structural
insight into multistage inhibition of CRISPR-Cas12a by
AcrVA4." Proc.Natl.Acad.Sci.USA,
116, 18928-18936. doi: 10.1073/pnas.1909400116.
|
Structure of lbcas12a-crrna complex bound to acrva4
(form b complex) . SNAP
output
|
|
6kle
|
viral protein-RNA |
cryo-EM (4.5 Å) |
Peng R, Xu X, Jing J, Wang M, Peng Q, Liu S, Wu Y,
Bao X, Wang P, Qi J, Gao GF, Shi Y |
(2020) "Structural
insight into arenavirus replication machinery."
Nature, 579, 615-619. doi:
10.1038/s41586-020-2114-2.
|
Monomeric structure of machupo virus polymerase bound
to vrna promoter . SNAP
output
|
|
6klh
|
viral protein-RNA |
cryo-EM (3.7 Å) |
Peng R, Xu X, Jing J, Wang M, Peng Q, Liu S, Wu Y,
Bao X, Wang P, Qi J, Gao GF, Shi Y |
(2020) "Structural
insight into arenavirus replication machinery."
Nature, 579, 615-619. doi:
10.1038/s41586-020-2114-2.
|
Dimeric structure of machupo virus polymerase bound to
vrna promoter . SNAP
output
|
|
6kr6
|
RNA binding protein-RNA |
X-ray (2.9 Å) |
Yamaguchi S, Oe A, Nishida KM, Yamashita K, Kajiya A,
Hirano S, Matsumoto N, Dohmae N, Ishitani R, Saito K,
Siomi H, Nishimasu H, Siomi MC, Nureki O |
(2020) "Crystal
structure of Drosophila Piwi." Nat Commun,
11, 858. doi: 10.1038/s41467-020-14687-1.
|
Crystal structure of drosophila piwi . SNAP output
|
|
6ktc
|
RNA binding protein-RNA |
X-ray (2.008 Å) |
Zou F, Tu R, Duan B, Yang Z, Ping Z, Song X, Chen S,
Price A, Li H, Scott A, Perera A, Li S, Xie T |
(2020) "DrosophilaYBX1
homolog YPS promotes ovarian germ line stem cell
development by preferentially recognizing
5-methylcytosine RNAs."
Proc.Natl.Acad.Sci.USA, 117,
3603-3609. doi: 10.1073/pnas.1910862117.
|
Crystal structure of ybx1 csd with m5c RNA . SNAP output
|
|
6kug
|
RNA binding protein-RNA |
X-ray (1.4 Å) |
Zou F, Tu R, Duan B, Yang Z, Ping Z, Song X, Chen S,
Price A, Li H, Scott A, Perera A, Li S, Xie T |
(2020) "DrosophilaYBX1
homolog YPS promotes ovarian germ line stem cell
development by preferentially recognizing
5-methylcytosine RNAs."
Proc.Natl.Acad.Sci.USA, 117,
3603-3609. doi: 10.1073/pnas.1910862117.
|
Crystal structure of ybx1 csd with RNA . SNAP output
|
|
6kuj
|
viral protein-RNA |
cryo-EM (3.4 Å) |
Peng Q, Liu Y, Peng R, Wang M, Yang W, Song H, Chen
Y, Liu S, Han M, Zhang X, Wang P, Yan J, Zhang B, Qi J,
Deng T, Gao GF, Shi Y |
(2019) "Structure
of influenza D virus polymerase bound to cRNA promoter
in Mode A conformation." NAT NANOTECHNOL.
doi: 10.1038/s41564-019-0487-5.
|
Structure of influenza d virus polymerase bound to crna
promoter in class 1 . SNAP output
|
|
6kuk
|
viral protein-RNA |
cryo-EM (3.9 Å) |
Peng Q, Liu Y, Peng R, Wang M, Yang W, Song H, Chen
Y, Liu S, Han M, Zhang X, Wang P, Yan J, Zhang B, Qi J,
Deng T, Gao GF, Shi Y |
(2019) "Structural
insight into RNA synthesis by influenza D
polymerase." Nat Microbiol,
4, 1750-1759. doi: 10.1038/s41564-019-0487-5.
|
Structure of influenza d virus polymerase bound to vrna
promoter in mode a conformation (class a1) . SNAP output
|
|
6kup
|
viral protein-RNA |
cryo-EM (4.3 Å) |
Peng Q, Liu Y, Peng R, Wang M, Yang W, Song H, Chen
Y, Liu S, Han M, Zhang X, Wang P, Yan J, Zhang B, Qi J,
Deng T, Gao GF, Shi Y |
(2019) "Structural
insight into RNA synthesis by influenza D
polymerase." Nat Microbiol,
4, 1750-1759. doi: 10.1038/s41564-019-0487-5.
|
Structure of influenza d virus polymerase bound to vrna
promoter in mode a conformation(class a2) . SNAP output
|
|
6kur
|
viral protein-RNA |
cryo-EM (3.7 Å) |
Peng Q, Liu Y, Peng R, Wang M, Yang W, Song H, Chen
Y, Liu S, Han M, Zhang X, Wang P, Yan J, Zhang B, Qi J,
Deng T, Gao GF, Shi Y |
(2019) "Structural
insight into RNA synthesis by influenza D
polymerase." Nat Microbiol,
4, 1750-1759. doi: 10.1038/s41564-019-0487-5.
|
Structure of influenza d virus polymerase bound to vrna
promoter in mode b conformation (class b1) . SNAP output
|
|
6kut
|
viral protein-RNA |
cryo-EM (4.1 Å) |
Peng Q, Liu Y, Peng R, Wang M, Yang W, Song H, Chen
Y, Liu S, Han M, Zhang X, Wang P, Yan J, Zhang B, Qi J,
Deng T, Gao GF, Shi Y |
(2019) "Structural
insight into RNA synthesis by influenza D
polymerase." Nat Microbiol,
4, 1750-1759. doi: 10.1038/s41564-019-0487-5.
|
Structure of influenza d virus polymerase bound to vrna
promoter in mode b conformation (class b2) . SNAP output
|
|
6kuu
|
viral protein-RNA |
cryo-EM (4.0 Å) |
Peng Q, Peng R, Qi J, Gao GF, Shi Y |
"Structure of influenza D virus polymerase bound to
vRNA promoter in Mode B conformation (Class B3)." |
Structure of influenza d virus polymerase bound to vrna
promoter in mode b conformation (class b3) . SNAP output
|
|
6kuv
|
viral protein-RNA |
cryo-EM (4.1 Å) |
Peng Q, Liu Y, Peng R, Wang M, Yang W, Song H, Chen
Y, Liu S, Han M, Zhang X, Wang P, Yan J, Zhang B, Qi J,
Deng T, Gao GF, Shi Y |
(2019) "Structural
insight into RNA synthesis by influenza D
polymerase." Nat Microbiol,
4, 1750-1759. doi: 10.1038/s41564-019-0487-5.
|
Structure of influenza d virus polymerase bound to crna
promoter in class 2 . SNAP output
|
|
6kwq
|
transferase-RNA |
X-ray (1.76 Å) |
Shi W, Ye HQ, Deng CL, Li R, Zhang B, Gong P |
(2020) "A
nucleobase-binding pocket in a viral RNA-dependent RNA
polymerase contributes to elongation complex
stability." Nucleic Acids Res.,
48, 1392-1405. doi: 10.1093/nar/gkz1170.
|
Crystal structure of enterovirus 71 polymerase
elongation complex (native form) . SNAP output
|
|
6kwr
|
transferase-RNA |
X-ray (2.5 Å) |
Shi W, Ye HQ, Deng CL, Li R, Zhang B, Gong P |
(2020) "A
nucleobase-binding pocket in a viral RNA-dependent RNA
polymerase contributes to elongation complex
stability." Nucleic Acids Res.,
48, 1392-1405. doi: 10.1093/nar/gkz1170.
|
Crystal structure of enterovirus 71 polymerase
elongation complex (ddctp form) . SNAP output
|
|
6kyv
|
immune system |
X-ray (3.0 Å) |
Kim KH, Hwang J, Kim JH, Son KP, Jang Y, Kim M, Kang
SJ, Lee JO, Kang JY, Choi BS |
(2020) "Structural
and biophysical properties of RIG-I bound to dsRNA with
G-U wobble base pairs." Rna Biol.,
17, 325-334. doi: 10.1080/15476286.2019.1700034.
|
Crystal structure of rig-i and hairpin RNA with g-u
wobble base pairs . SNAP
output
|
|
6l1w
|
RNA binding protein-RNA |
X-ray (2.194 Å) |
Luo X, Wang X, Gao Y, Zhu J, Liu S, Gao G, Gao P |
(2020) "Molecular
Mechanism of RNA Recognition by Zinc-Finger Antiviral
Protein." Cell Rep, 30,
46-52.e4. doi: 10.1016/j.celrep.2019.11.116.
|
Zinc-finger antiviral protein (zap) bound to RNA .
SNAP output
|
|
6l5n
|
RNA binding protein-RNA |
X-ray (2.242 Å) |
Chen Z, Li Z, Hu X, Xie F, Kuang S, Zhan B, Gao W,
Chen X, Gao S, Li Y, Wang Y, Qian F, Ding C, Gan J, Ji C,
Xu X, Zhou Z, Huang J, He HH, Li J |
(2020) "Structural
Basis of Human Helicase DDX21 in RNA Binding,
Unwinding, and Antiviral Signal Activation."
Adv Sci, 7, 2000532. doi:
10.1002/advs.202000532.
|
Crystal structure of human dead-box RNA helicase ddx21
at post-unwound state . SNAP output
|
|
6las
|
RNA |
X-ray (2.708 Å) |
Sun A, Gasser C, Li F, Chen H, Mair S, Krasheninina
O, Micura R, Ren A |
(2019) "SAM-VI
riboswitch structure and signature for ligand
discrimination." Nat Commun,
10, 5728. doi: 10.1038/s41467-019-13600-9.
|
The wildtype sam-vi riboswitch bound to sam . SNAP output
|
|
6lau
|
RNA |
X-ray (3.109 Å) |
Sun A, Gasser C, Li F, Chen H, Mair S, Krasheninina
O, Micura R, Ren A |
(2019) "SAM-VI
riboswitch structure and signature for ligand
discrimination." Nat Commun,
10, 5728. doi: 10.1038/s41467-019-13600-9.
|
The wildtype sam-vi riboswitch bound to sah . SNAP output
|
|
6lax
|
RNA |
X-ray (2.7 Å) |
Sun A, Gasser C, Li F, Chen H, Mair S, Krasheninina
O, Micura R, Ren A |
(2019) "SAM-VI
riboswitch structure and signature for ligand
discrimination." Nat Commun,
10, 5728. doi: 10.1038/s41467-019-13600-9.
|
The mutant sam-vi riboswitch (u6c) bound to sam .
SNAP output
|
|
6laz
|
RNA |
X-ray (2.76 Å) |
Sun A, Gasser C, Li F, Chen H, Mair S, Krasheninina
O, Micura R, Ren A |
(2019) "SAM-VI
riboswitch structure and signature for ligand
discrimination." Nat Commun,
10, 5728. doi: 10.1038/s41467-019-13600-9.
|
The wildtype sam-vi riboswitch bound to a n-mustard sam
analog m1 . SNAP
output
|
|
6lkq
|
translation |
X-ray (3.1 Å) |
Zhang L, Wang YH, Zhang X, Lancaster L, Zhou J,
Noller HF |
(2020) "The
structural basis for inhibition of ribosomal
translocation by viomycin."
Proc.Natl.Acad.Sci.USA, 117,
10271-10277. doi: 10.1073/pnas.2002888117.
|
The structural basis for inhibition of ribosomal
translocation by viomycin . SNAP output
|
|
6llb
|
RNA binding protein-RNA |
X-ray (2.6 Å) |
Li J, Hou Y, Gu X, Yue L, Guo L, Li D, Dong X |
(2020) "A newly
identified duplex RNA unwinding activity of archaeal
RNase J depends on processive exoribonucleolysis
coupled steric occlusion by its structural archaeal
loops." Rna Biol., 17,
1480-1491. doi: 10.1080/15476286.2020.1777379.
|
Crystal structure of mpy-rnase j (mutant s247a), an
archaeal rnase j from methanolobus psychrophilus r15,
in complex with 6 nt RNA . SNAP output
|
|
6lnc
|
immune system |
cryo-EM (3.21 Å) |
Wang B, Xu W, Yang H |
(2020) "Structural
basis of a Tn7-like transposase recruitment and DNA
loading to CRISPR-Cas surveillance complex."
Cell Res., 30, 185-187. doi:
10.1038/s41422-020-0274-0.
|
Cryoem structure of cascade-tniq complex . SNAP output
|
|
6lqm
|
ribosome |
cryo-EM (3.09 Å) |
Liang X, Zuo MQ, Zhang Y, Li N, Ma C, Dong MQ, Gao
N |
(2020) "Structural
snapshots of human pre-60S ribosomal particles before
and after nuclear export." Nat Commun,
11, 3542. doi: 10.1038/s41467-020-17237-x.
|
cryo-EM structure of a pre-60s ribosomal subunit -
state c . SNAP
output
|
|
6lqp
|
ribosome |
cryo-EM (3.2 Å) |
Du Y, An W, Zhu X, Sun Q, Qi J, Ye K |
(2020) "Cryo-EM
structure of 90 S small ribosomal subunit precursors in
transition states." Science,
369, 1477-1481. doi: 10.1126/science.aba9690.
|
cryo-EM structure of 90s small subunit preribosomes in
transition states (state a) . SNAP output
|
|
6lqq
|
ribosome |
cryo-EM (4.1 Å) |
Du Y, An W, Zhu X, Sun Q, Qi J, Ye K |
(2020) "Cryo-EM
structure of 90 S small ribosomal subunit precursors in
transition states." Science,
369, 1477-1481. doi: 10.1126/science.aba9690.
|
cryo-EM structure of 90s small subunit preribosomes in
transition states (state b) . SNAP output
|
|
6lqr
|
ribosome |
cryo-EM (8.6 Å) |
Du Y, An W, Zhu X, Sun Q, Qi J, Ye K |
(2020) "Cryo-EM
structure of 90 S small ribosomal subunit precursors in
transition states." Science,
369, 1477-1481. doi: 10.1126/science.aba9690.
|
cryo-EM structure of 90s small subunit preribosomes in
transition states (state c) . SNAP output
|
|
6lqs
|
ribosome |
cryo-EM (3.8 Å) |
Du Y, An W, Zhu X, Sun Q, Qi J, Ye K |
(2020) "Cryo-EM
structure of 90 S small ribosomal subunit precursors in
transition states." Science,
369, 1477-1481. doi: 10.1126/science.aba9690.
|
cryo-EM structure of 90s small subunit preribosomes in
transition states (state d) . SNAP output
|
|
6lqt
|
ribosome |
cryo-EM (4.9 Å) |
Du Y, An W, Zhu X, Sun Q, Qi J, Ye K |
(2020) "Cryo-EM
structure of 90 S small ribosomal subunit precursors in
transition states." Science,
369, 1477-1481. doi: 10.1126/science.aba9690.
|
cryo-EM structure of 90s small subunit preribosomes in
transition states (state e) . SNAP output
|
|
6lqu
|
ribosome |
cryo-EM (3.7 Å) |
Du Y, An W, Zhu X, Sun Q, Qi J, Ye K |
(2020) "Cryo-EM
structure of 90 S small ribosomal subunit precursors in
transition states." Science,
369, 1477-1481. doi: 10.1126/science.aba9690.
|
cryo-EM structure of 90s small subunit preribosomes in
transition states (state a1) . SNAP output
|
|
6lqv
|
ribosome |
cryo-EM (4.8 Å) |
Du Y, An W, Zhu X, Sun Q, Qi J, Ye K |
(2020) "Cryo-EM
structure of 90 S small ribosomal subunit precursors in
transition states." Science,
369, 1477-1481. doi: 10.1126/science.aba9690.
|
cryo-EM structure of 90s small subunit preribosomes in
transition states (state c1) . SNAP output
|
|
6lse
|
transferase-RNA |
X-ray (2.25 Å) |
Wang M, Li R, Shu B, Jing X, Ye HQ, Gong P |
(2020) "Stringent
control of the RNA-dependent RNA polymerase
translocation revealed by multiple intermediate
structures." Nat Commun,
11, 2605. doi: 10.1038/s41467-020-16234-4.
|
Crystal structure of the enterovirus 71 polymerase
elongation complex (c3s6a-c3s6b form) . SNAP output
|
|
6lsf
|
transferase-DNA |
X-ray (2.152 Å) |
Wang M, Li R, Shu B, Jing X, Ye HQ, Gong P |
(2020) "Stringent
control of the RNA-dependent RNA polymerase
translocation revealed by multiple intermediate
structures." Nat Commun,
11, 2605. doi: 10.1038/s41467-020-16234-4.
|
Crystal structure of the enterovirus 71 polymerase
elongation complex (c2s6ra-c2s6rb form) . SNAP output
|
|
6lsg
|
transferase-RNA |
X-ray (2.14 Å) |
Wang M, Li R, Shu B, Jing X, Ye HQ, Gong P |
(2020) "Stringent
control of the RNA-dependent RNA polymerase
translocation revealed by multiple intermediate
structures." Nat Commun,
11, 2605. doi: 10.1038/s41467-020-16234-4.
|
Crystal structure of the enterovirus 71 polymerase
elongation complex (c0s6m form) . SNAP output
|
|
6lsh
|
transferase-RNA |
X-ray (2.231 Å) |
Wang M, Li R, Shu B, Jing X, Ye HQ, Gong P |
(2020) "Stringent
control of the RNA-dependent RNA polymerase
translocation revealed by multiple intermediate
structures." Nat Commun,
11, 2605. doi: 10.1038/s41467-020-16234-4.
|
Crystal structure of the enterovirus 71 polymerase
elongation complex (c2s6m form) . SNAP output
|
|
6lsr
|
ribosome |
cryo-EM (3.13 Å) |
Liang X, Zuo MQ, Zhang Y, Li N, Ma C, Dong MQ, Gao
N |
(2020) "Structural
snapshots of human pre-60S ribosomal particles before
and after nuclear export." Nat Commun,
11, 3542. doi: 10.1038/s41467-020-17237-x.
|
cryo-EM structure of a pre-60s ribosomal subunit -
state b . SNAP
output
|
|
6lss
|
ribosome |
cryo-EM (3.23 Å) |
Liang X, Zuo MQ, Zhang Y, Li N, Ma C, Dong MQ, Gao
N |
(2020) "Structural
snapshots of human pre-60S ribosomal particles before
and after nuclear export." Nat Commun,
11, 3542. doi: 10.1038/s41467-020-17237-x.
|
cryo-EM structure of a pre-60s ribosomal subunit -
state prea . SNAP
output
|
|
6lt7
|
hydrolase-RNA |
X-ray (2.7 Å) |
Yin C, Bai G, Zhang Y, Huang J |
(2021) "Crystal
structure of human RPP20-RPP25 proteins in complex with
the P3 domain of lncRNA RMRP."
J.Struct.Biol., 213, 107704.
doi: 10.1016/j.jsb.2021.107704.
|
Crystal structure of human rpp20-rpp25 proteins in
complex with the p3 domain of lncrna rmrp . SNAP output
|
|
6ltp
|
hydrolase-RNA |
X-ray (3.4 Å) |
Huang X, Sun W, Cheng Z, Chen M, Li X, Wang J, Sheng
G, Gong W, Wang Y |
(2020) "Structural
basis for two metal-ion catalysis of DNA cleavage by
Cas12i2." Nat Commun, 11,
5241. doi: 10.1038/s41467-020-19072-6.
|
Crystal structure of cas12i2 binary complex . SNAP output
|
|
6lu8
|
ribosome |
cryo-EM (3.13 Å) |
Liang X, Zuo MQ, Zhang Y, Li N, Ma C, Dong MQ, Gao
N |
(2020) "Structural
snapshots of human pre-60S ribosomal particles before
and after nuclear export." Nat Commun,
11, 3542. doi: 10.1038/s41467-020-17237-x.
|
cryo-EM structure of a human pre-60s ribosomal subunit
- state a . SNAP
output
|
|
6lvr
|
RNA binding protein |
X-ray (2.85 Å) |
Teramoto T, Kaitany KJ, Kakuta Y, Kimura M, Fierke
CA, Hall TMT |
(2020) "Pentatricopeptide
repeats of protein-only RNase P use a distinct mode to
recognize conserved bases and structural elements of
pre-tRNA." Nucleic Acids Res.,
48, 11815-11826. doi: 10.1093/nar/gkaa627.
|
Crystal structure of the ppr domain of arabidopsis
thaliana protein-only rnase p 1 (prorp1) in complex
with trna . SNAP
output
|
|
6lxd
|
hydrolase-RNA binding protein-RNA |
cryo-EM (3.9 Å) |
Jin W, Wang J, Liu CP, Wang HW, Xu RM |
(2020) "Structural
Basis for pri-miRNA Recognition by Drosha."
Mol.Cell, 78, 423. doi:
10.1016/j.molcel.2020.02.024.
|
Pri-mirna bound drosha-dgcr8 complex . SNAP output
|
|
6m62
|
ribosome |
cryo-EM (3.2 Å) |
Micic J, Li Y, Wu S, Wilson D, Tutuncuoglu B, Gao N,
Woolford Jr JL |
(2020) "Coupling
of 5S RNP rotation with maturation of functional
centers during large ribosomal subunit assembly."
Nat Commun, 11, 3751. doi:
10.1038/s41467-020-17534-5.
|
cryo-EM structure of eukaryotic pre-60s ribosome
subunit from saccharomyces cerevisiae rpf2 delta
255-344 strain, c4 state. . SNAP output
|
|
6m6r
|
RNA binding protein-RNA |
X-ray (1.89 Å) |
Li K, Zheng J, Wirawan M, Trinh NM, Fedorova O,
Griffin PR, Pyle AM, Luo D |
(2021) "Insights
into the structure and RNA-binding specificity of
Caenorhabditis elegans Dicer-related helicase 3
(DRH-3)." Nucleic Acids Res.,
49, 9978-9991. doi: 10.1093/nar/gkab712.
|
Crystal structure of caenorhabditis elegans
dicer-related helicase 3 (drh-3) c-terminal domain with
5'-ppp 8-mer ssrna . SNAP output
|
|
6m6s
|
RNA binding protein-RNA |
X-ray (1.6 Å) |
Li K, Zheng J, Wirawan M, Trinh NM, Fedorova O,
Griffin PR, Pyle AM, Luo D |
(2021) "Insights
into the structure and RNA-binding specificity of
Caenorhabditis elegans Dicer-related helicase 3
(DRH-3)." Nucleic Acids Res.,
49, 9978-9991. doi: 10.1093/nar/gkab712.
|
Crystal structure of caenorhabditis elegans
dicer-related helicase 3 (drh-3) c-terminal domain with
5'-ppp 12-mer dsrna . SNAP output
|
|
6m6v
|
antitoxin |
X-ray (3.08 Å) |
Yao J, Zhen X, Tang K, Liu T, Xu X, Chen Z, Guo Y,
Liu X, Wood TK, Ouyang S, Wang X |
(2020) "Novel
polyadenylylation-dependent neutralization mechanism of
the HEPN/MNT toxin/antitoxin system." Nucleic
Acids Res., 48, 11054-11067. doi:
10.1093/nar/gkaa855.
|
Crystal structure the toxin-antitoxin mnta-hept .
SNAP output
|
|
6m7d
|
nuclear protein-RNA |
cryo-EM (2.9 Å) |
Shen Q, Shan H, Zhang N |
"structure of the nucleocapsid of sendai virus at 2.9
Angstroms resolution." |
Structure of ncleoprotein of sendai virus . SNAP output
|
|
6m7k
|
oxidoreductase |
X-ray (1.1 Å) |
Whiteley AT, Eaglesham JB, de Oliveira Mann CC,
Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King
DS, Lee ASY, Mekalanos JJ, Kranzusch PJ |
(2019) "Bacterial
cGAS-like enzymes synthesize diverse nucleotide
signals." Nature, 567,
194-199. doi: 10.1038/s41586-019-0953-5.
|
Structure of mouse recon (akr1c13) in complex with
cyclic amp-amp-gmp (caag) . SNAP output
|
|
6mcb
|
hydrolase-RNA-viral protein |
cryo-EM (3.4 Å) |
Jiang F, Liu JJ, Osuna BA, Xu M, Berry JD, Rauch BJ,
Nogales E, Bondy-Denomy J, Doudna JA |
(2019) "Temperature-Responsive
Competitive Inhibition of CRISPR-Cas9." Mol.
Cell, 73, 601. doi: 10.1016/j.molcel.2018.11.016.
|
Cryoem structure of acriia2 in complex with crispr-cas9
. SNAP output
|
|
6mcc
|
hydrolase-RNA-viral protein |
cryo-EM (3.9 Å) |
Jiang F, Liu JJ, Osuna BA, Xu M, Berry JD, Rauch BJ,
Nogales E, Bondy-Denomy J, Doudna JA |
(2019) "Temperature-Responsive
Competitive Inhibition of CRISPR-Cas9." Mol.
Cell, 73, 601. doi: 10.1016/j.molcel.2018.11.016.
|
Cryoem structure of acriia2 homolog in complex with
crispr-cas9 . SNAP
output
|
|
6mce
|
transcription |
NMR |
Pham VV, Salguero C, Khan SN, Meagher JL, Brown WC,
Humbert N, de Rocquigny H, Smith JL, D'Souza VM |
(2018) "HIV-1
Tat interactions with cellular 7SK and viral TAR RNAs
identifies dual structural mimicry." Nat
Commun, 9, 4266. doi: 10.1038/s41467-018-06591-6.
|
Solution structure of hiv-1 tar with tat RNA binding
domain . SNAP output
|
|
6mcf
|
transcription |
NMR |
Pham VV, Salguero C, Khan SN, Meagher JL, Brown WC,
Humbert N, de Rocquigny H, Smith JL, D'Souza VM |
(2018) "HIV-1
Tat interactions with cellular 7SK and viral TAR RNAs
identifies dual structural mimicry." Nat
Commun, 9, 4266. doi: 10.1038/s41467-018-06591-6.
|
Solution structure of 7sk stem-loop 1 with hiv-1 tat
RNA binding domain . SNAP output
|
|
6mfn
|
hydrolase-RNA |
X-ray (2.5 Å) |
Sheu-Gruttadauria J, Pawlica P, Klum SM, Wang S,
Yario TA, Schirle Oakdale NT, Steitz JA, MacRae IJ |
(2019) "Structural
Basis for Target-Directed MicroRNA Degradation."
Mol.Cell, 75, 1243. doi:
10.1016/j.molcel.2019.06.019.
|
Human argonaute2-mir-27a bound to hsur1 target RNA .
SNAP output
|
|
6mkn
|
ribosome |
X-ray (3.46 Å) |
Vangaveti S, Cantara WA, Spears JL, DeMirci H, Murphy
IV FV, Ranganathan SV, Sarachan KL, Agris PF |
(2020) "A
Structural Basis for Restricted Codon Recognition
Mediated by 2-thiocytidine in tRNA Containing a Wobble
Position Inosine." J.Mol.Biol.,
432, 913-929. doi: 10.1016/j.jmb.2019.12.016.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with an inosine (i34) modified
anticodon stem loop (asl) of escherichia coli transfer
RNA arginine 2 (trnaarg2) bound to an mrna with an
cgu-codon in the a-site and paromomycin . SNAP output
|
|
6mpf
|
ribosome |
X-ray (3.33 Å) |
Vangaveti S, Cantara WA, Spears JL, DeMirci H, Murphy
IV FV, Ranganathan SV, Sarachan KL, Agris PF |
(2020) "A
Structural Basis for Restricted Codon Recognition
Mediated by 2-thiocytidine in tRNA Containing a Wobble
Position Inosine." J.Mol.Biol.,
432, 913-929. doi: 10.1016/j.jmb.2019.12.016.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a 2-thiocytidine (s2c32) and
inosine (i34) modified anticodon stem loop (asl) of
escherichia coli transfer RNA arginine 1 (trnaarg1)
bound to an mrna with an cgc-codon in the a-site and
paromomycin . SNAP
output
|
|
6mpi
|
ribosome |
X-ray (3.33 Å) |
Vangaveti S, Cantara WA, Spears JL, DeMirci H, Murphy
IV FV, Ranganathan SV, Sarachan KL, Agris PF |
(2020) "A
Structural Basis for Restricted Codon Recognition
Mediated by 2-thiocytidine in tRNA Containing a Wobble
Position Inosine." J.Mol.Biol.,
432, 913-929. doi: 10.1016/j.jmb.2019.12.016.
|
Structure of the thermus thermophilus 30s ribosomal
subunit complexed with a 2-thiocytidine (s2c32) and
inosine (i34) modified anticodon stem loop (asl) of
escherichia coli transfer RNA arginine 1 (trnaarg1)
bound to an mrna with an cgu-codon in the a-site and
paromomycin . SNAP
output
|
|
6msf
|
virus-RNA |
X-ray (2.8 Å) |
Convery MA, Rowsell S, Stonehouse NJ, Ellington AD,
Hirao I, Murray JB, Peabody DS, Phillips SE, Stockley
PG |
(1998) "Crystal
structure of an RNA aptamer-protein complex at 2.8 A
resolution." Nat.Struct.Biol.,
5, 133-139. doi: 10.1038/nsb0298-133.
|
F6 aptamer ms2 coat protein complex . SNAP output
|
|
6mtb
|
ribosome |
cryo-EM (3.6 Å) |
Brown A, Baird MR, Yip MC, Murray J, Shao S |
(2018) "Structures
of translationally inactive mammalian ribosomes."
Elife, 7. doi: 10.7554/eLife.40486.
|
Rabbit 80s ribosome with p- and z-site trnas (unrotated
state) . SNAP output
|
|
6mtc
|
ribosome |
cryo-EM (3.4 Å) |
Brown A, Baird MR, Yip MC, Murray J, Shao S |
(2018) "Structures
of translationally inactive mammalian ribosomes."
Elife, 7. doi: 10.7554/eLife.40486.
|
Rabbit 80s ribosome with z-site trna and ifrd2
(unrotated state) . SNAP
output
|
|
6mtd
|
ribosome |
cryo-EM (3.3 Å) |
Brown A, Baird MR, Yip MC, Murray J, Shao S |
(2018) "Structures
of translationally inactive mammalian ribosomes."
Elife, 7. doi: 10.7554/eLife.40486.
|
Rabbit 80s ribosome with eef2 and serbp1 (unrotated
state with 40s head swivel) . SNAP output
|
|
6mte
|
ribosome |
cryo-EM (3.4 Å) |
Brown A, Baird MR, Yip MC, Murray J, Shao S |
(2018) "Structures
of translationally inactive mammalian ribosomes."
Elife, 7. doi: 10.7554/eLife.40486.
|
Rabbit 80s ribosome with eef2 and serbp1 (rotated
state) . SNAP output
|
|
6mur
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Jia N, Mo CY, Wang C, Eng ET, Marraffini LA, Patel
DJ |
(2019) "Type
III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA
Cleavage, DNase Activity Regulation, and
Autoimmunity." Mol. Cell,
73, 264. doi: 10.1016/j.molcel.2018.11.007.
|
cryo-EM structure of csm-crrna-target RNA ternary
complex in type iii-a crispr-cas system . SNAP output
|
|
6mus
|
RNA binding protein-RNA |
cryo-EM (3.6 Å) |
Jia N, Mo CY, Wang C, Eng ET, Marraffini LA, Patel
DJ |
(2019) "Type
III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA
Cleavage, DNase Activity Regulation, and
Autoimmunity." Mol. Cell,
73, 264. doi: 10.1016/j.molcel.2018.11.007.
|
cryo-EM structure of larger csm-crrna-target RNA
ternary complex in type iii-a crispr-cas system .
SNAP output
|
|
6mut
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Jia N, Mo CY, Wang C, Eng ET, Marraffini LA, Patel
DJ |
(2019) "Type
III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA
Cleavage, DNase Activity Regulation, and
Autoimmunity." Mol. Cell,
73, 264. doi: 10.1016/j.molcel.2018.11.007.
|
cryo-EM structure of ternary csm-crrna-target RNA with
anti-tag sequence complex in type iii-a crispr-cas
system . SNAP output
|
|
6muu
|
RNA binding protein-RNA |
cryo-EM (3.0 Å) |
Jia N, Mo CY, Wang C, Eng ET, Marraffini LA, Patel
DJ |
(2019) "Type
III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA
Cleavage, DNase Activity Regulation, and
Autoimmunity." Mol. Cell,
73, 264. doi: 10.1016/j.molcel.2018.11.007.
|
cryo-EM structure of csm-crrna binary complex in type
iii-a crispr-cas system . SNAP output
|
|
6mwn
|
RNA-immune system |
X-ray (2.838 Å) |
Koirala D, Shao Y, Koldobskaya Y, Fuller JR, Watkins
AM, Shelke SA, Pilipenko EV, Das R, Rice PA, Piccirilli
JA |
(2019) "A
conserved RNA structural motif for organizing topology
within picornaviral internal ribosome entry sites."
Nat Commun, 10, 3629. doi:
10.1038/s41467-019-11585-z.
|
Crystal structure of hepatitis a virus ires domain v in
complex with fab havx . SNAP output
|
|
6n1d
|
ribosome |
X-ray (3.2 Å) |
Zhou J, Lancaster L, Donohue JP, Noller HF |
(2019) "Spontaneous
ribosomal translocation of mRNA and tRNAs into a
chimeric hybrid state." Proc. Natl. Acad. Sci.
U.S.A., 116, 7813-7818. doi:
10.1073/pnas.1901310116.
|
X-ray crystal complex showing spontaneous ribosomal
translocation of mrna and trnas into a chimeric hybrid
state . SNAP output
|
|
6n4o
|
RNA binding protein-RNA |
X-ray (2.899 Å) |
Sheu-Gruttadauria J, Xiao Y, Gebert LF, MacRae
IJ |
(2019) "Beyond
the seed: structural basis for supplementary microRNA
targeting by human Argonaute2." Embo J.,
38, e101153. doi: 10.15252/embj.2018101153.
|
Human argonaute2-mir-122 bound to a seed and
supplementary paired target . SNAP output
|
|
6n6a
|
RNA binding protein-RNA |
X-ray (1.5 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Vibrio cholerae oligoribonuclease bound to pgg .
SNAP output
|
|
6n6c
|
RNA binding protein-RNA |
X-ray (1.619 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Vibrio cholerae oligoribonuclease bound to paa .
SNAP output
|
|
6n6d
|
RNA binding protein-RNA |
X-ray (1.534 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Vibrio cholerae oligoribonuclease bound to pag .
SNAP output
|
|
6n6e
|
RNA binding protein-RNA |
X-ray (1.578 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Vibrio cholerae oligoribonuclease bound to pga .
SNAP output
|
|
6n6f
|
RNA binding protein-RNA |
X-ray (1.735 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Vibrio cholerae oligoribonuclease bound to pgc .
SNAP output
|
|
6n6g
|
RNA binding protein-RNA |
X-ray (2.018 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Vibrio cholerae oligoribonuclease bound to pcg .
SNAP output
|
|
6n6h
|
RNA binding protein-RNA |
X-ray (1.757 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Vibrio cholerae oligoribonuclease bound to pcpu .
SNAP output
|
|
6n6i
|
RNA binding protein-RNA |
X-ray (1.431 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Human rexo2 bound to pgg . SNAP output
|
|
6n6j
|
RNA binding protein-RNA |
X-ray (1.317 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Human rexo2 bound to paa . SNAP output
|
|
6n6k
|
RNA binding protein-RNA |
X-ray (1.418 Å) |
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H,
Turdiev A, Winkler WC, Sondermann H, Lee VT |
(2019) "A
dedicated diribonucleotidase resolves a key bottleneck
for the terminal step of RNA degradation."
Elife, 8. doi: 10.7554/eLife.46313.
|
Human rexo2 bound to pag . SNAP output
|
|
6n7p
|
RNA binding protein |
cryo-EM (3.6 Å) |
Li X, Liu S, Zhang L, Issaian A, Hill RC, Espinosa S,
Shi S, Cui Y, Kappel K, Das R, Hansen KC, Zhou ZH, Zhao
R |
(2019) "A
unified mechanism for intron and exon definition and
back-splicing." Nature,
573, 375-380. doi: 10.1038/s41586-019-1523-6.
|
S. cerevisiae spliceosomal e complex (ubc4) . SNAP output
|
|
6n7r
|
RNA binding protein |
cryo-EM (3.2 Å) |
Li X, Liu S, Zhang L, Issaian A, Hill RC, Espinosa S,
Shi S, Cui Y, Kappel K, Das R, Hansen KC, Zhou ZH, Zhao
R |
(2019) "A
unified mechanism for intron and exon definition and
back-splicing." Nature,
573, 375-380. doi: 10.1038/s41586-019-1523-6.
|
Saccharomyces cerevisiae spliceosomal e complex (act1)
. SNAP output
|
|
6n7x
|
RNA binding protein-RNA |
cryo-EM (3.6 Å) |
Li X, Liu S, Jiang J, Zhang L, Espinosa S, Hill RC,
Hansen KC, Zhou ZH, Zhao R |
(2017) "CryoEM
structure of Saccharomyces cerevisiae U1 snRNP offers
insight into alternative splicing." Nat
Commun, 8, 1035. doi: 10.1038/s41467-017-01241-9.
|
S. cerevisiae u1 snrnp . SNAP output
|
|
6n8j
|
ribosome |
cryo-EM (3.5 Å) |
Zhou Y, Musalgaonkar S, Johnson AW, Taylor DW |
(2019) "Tightly-orchestrated
rearrangements govern catalytic center assembly of the
ribosome." Nat Commun,
10, 958. doi: 10.1038/s41467-019-08880-0.
|
cryo-EM structure of late nuclear (ln) pre-60s
ribosomal subunit . SNAP
output
|
|
6n8k
|
ribosome |
cryo-EM (3.6 Å) |
Zhou Y, Musalgaonkar S, Johnson AW, Taylor DW |
(2019) "Tightly-orchestrated
rearrangements govern catalytic center assembly of the
ribosome." Nat Commun,
10, 958. doi: 10.1038/s41467-019-08880-0.
|
cryo-EM structure of early cytoplasmic-immediate (eci)
pre-60s ribosomal subunit . SNAP output
|
|
6n8l
|
ribosome |
cryo-EM (3.6 Å) |
Zhou Y, Musalgaonkar S, Johnson AW, Taylor DW |
(2019) "Tightly-orchestrated
rearrangements govern catalytic center assembly of the
ribosome." Nat Commun,
10, 958. doi: 10.1038/s41467-019-08880-0.
|
cryo-EM structure of early cytoplasmic-late (ecl)
pre-60s ribosomal subunit . SNAP output
|
|
6n8m
|
ribosome |
cryo-EM (3.5 Å) |
Zhou Y, Musalgaonkar S, Johnson AW, Taylor DW |
(2019) "Tightly-orchestrated
rearrangements govern catalytic center assembly of the
ribosome." Nat Commun,
10, 958. doi: 10.1038/s41467-019-08880-0.
|
cryo-EM structure of pre-lsg1 (pl) pre-60s ribosomal
subunit . SNAP
output
|
|
6n8n
|
ribosome |
cryo-EM (3.8 Å) |
Zhou Y, Musalgaonkar S, Johnson AW, Taylor DW |
(2019) "Tightly-orchestrated
rearrangements govern catalytic center assembly of the
ribosome." Nat Commun,
10, 958. doi: 10.1038/s41467-019-08880-0.
|
cryo-EM structure of lsg1-engaged (le) pre-60s
ribosomal subunit . SNAP
output
|
|
6n8o
|
ribosome |
cryo-EM (3.5 Å) |
Zhou Y, Musalgaonkar S, Johnson AW, Taylor DW |
(2019) "Tightly-orchestrated
rearrangements govern catalytic center assembly of the
ribosome." Nat Commun,
10, 958. doi: 10.1038/s41467-019-08880-0.
|
cryo-EM structure of rpl10-inserted (ri) pre-60s
ribosomal subunit . SNAP
output
|
|
6n9e
|
ribosome |
X-ray (3.7 Å) |
Melnikov SV, Khabibullina NF, Mairhofer E,
Vargas-Rodriguez O, Reynolds NM, Micura R, Soll D,
Polikanov YS |
(2019) "Mechanistic
insights into the slow peptide bond formation with
D-amino acids in the ribosomal active site."
Nucleic Acids Res., 47,
2089-2100. doi: 10.1093/nar/gky1211.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with a short substrate mimic cc-pmn
and bound to mrna and p-site trna at 3.7a resolution .
SNAP output
|
|
6n9f
|
ribosome |
X-ray (3.7 Å) |
Melnikov SV, Khabibullina NF, Mairhofer E,
Vargas-Rodriguez O, Reynolds NM, Micura R, Soll D,
Polikanov YS |
(2019) "Mechanistic
insights into the slow peptide bond formation with
D-amino acids in the ribosomal active site."
Nucleic Acids Res., 47,
2089-2100. doi: 10.1093/nar/gky1211.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with a short substrate mimic
acca-dphe and bound to mrna and p-site trna at 3.7a
resolution . SNAP
output
|
|
6nbj
|
RNA binding protein |
X-ray (2.94 Å) |
Stec B |
(2023) "Discovery of the Universal tRNA Binding Mode
for the TsaD-like Components of the t6A tRNA
Modification Pathway." Biophysica,
3. doi: 10.3390/biophysica3020019.
|
Qri7 . SNAP output
|
|
6nd4
|
ribosome |
cryo-EM (4.3 Å) |
Hunziker M, Barandun J, Buzovetsky O, Steckler C,
Molina H, Klinge S |
(2019) "Conformational
switches control early maturation of the eukaryotic
small ribosomal subunit." Elife,
8. doi: 10.7554/eLife.45185.
|
Conformational switches control early maturation of the
eukaryotic small ribosomal subunit . SNAP output
|
|
6nd5
|
ribosome-antibiotic |
X-ray (2.6 Å) |
Svetlov MS, Plessa E, Chen CW, Bougas A, Krokidis MG,
Dinos GP, Polikanov YS |
(2019) "High-resolution
crystal structures of ribosome-bound chloramphenicol
and erythromycin provide the ultimate basis for their
competition." RNA, 25,
600-606. doi: 10.1261/rna.069260.118.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with chloramphenicol and bound to
mrna and a-, p-, and e-site trnas at 2.60a resolution .
SNAP output
|
|
6nd6
|
ribosome-antibiotic |
X-ray (2.85 Å) |
Svetlov MS, Plessa E, Chen CW, Bougas A, Krokidis MG,
Dinos GP, Polikanov YS |
(2019) "High-resolution
crystal structures of ribosome-bound chloramphenicol
and erythromycin provide the ultimate basis for their
competition." RNA, 25,
600-606. doi: 10.1261/rna.069260.118.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with erythromycin and bound to mrna
and a-, p-, and e-site trnas at 2.85a resolution .
SNAP output
|
|
6ndk
|
ribosome |
X-ray (3.64 Å) |
Nguyen HA, Hoffer ED, Dunham CM |
(2019) "Importance
of a tRNA anticodon loop modification and a conserved,
noncanonical anticodon stem pairing intRNACGGProfor
decoding." J. Biol. Chem.,
294, 5281-5291. doi: 10.1074/jbc.RA119.007410.
|
Structure of aslsufa6 a37.5 bound to the 70s a site .
SNAP output
|
|
6neq
|
ribosomal protein |
cryo-EM (3.32 Å) |
Koripella RK, Sharma MR, Haque ME, Risteff P,
Spremulli LL, Agrawal RK |
(2019) "Structure
of Human Mitochondrial Translation Initiation Factor 3
Bound to the Small Ribosomal Subunit."
iScience, 12, 76-86. doi:
10.1016/j.isci.2018.12.030.
|
Structure of human mitochondrial translation initiation
factor 3 bound to the small ribosomal subunit-class-ii
. SNAP output
|
|
6nf8
|
ribosomal protein |
cryo-EM (3.48 Å) |
Koripella RK, Sharma MR, Haque ME, Risteff P,
Spremulli LL, Agrawal RK |
(2019) "Structure
of Human Mitochondrial Translation Initiation Factor 3
Bound to the Small Ribosomal Subunit."
iScience, 12, 76-86. doi:
10.1016/j.isci.2018.12.030.
|
Structure of human mitochondrial translation initiation
factor 3 bound to the small ribosomal subunit -class i
. SNAP output
|
|
6nm9
|
unknown function-RNA |
cryo-EM (3.38 Å) |
Zhang H, Li Z, Daczkowski CM, Gabel C, Mesecar AD,
Chang L |
(2019) "Structural
Basis for the Inhibition of CRISPR-Cas12a by
Anti-CRISPR Proteins." Cell Host Microbe,
25, 815. doi: 10.1016/j.chom.2019.05.004.
|
Cryoem structure of the lbcas12a-crrna-acrva4 dimer .
SNAP output
|
|
6nma
|
unknown function-RNA |
cryo-EM (3.38 Å) |
Zhang H, Li Z, Daczkowski CM, Gabel C, Mesecar AD,
Chang L |
(2019) "Structural
Basis for the Inhibition of CRISPR-Cas12a by
Anti-CRISPR Proteins." Cell Host Microbe,
25, 815. doi: 10.1016/j.chom.2019.05.004.
|
Cryoem structure of the lbcas12a-crrna-acrva4 complex .
SNAP output
|
|
6nmc
|
unknown function-RNA |
cryo-EM (4.24 Å) |
Zhang H, Li Z, Daczkowski CM, Gabel C, Mesecar AD,
Chang L |
(2019) "Structural
Basis for the Inhibition of CRISPR-Cas12a by
Anti-CRISPR Proteins." Cell Host Microbe,
25, 815. doi: 10.1016/j.chom.2019.05.004.
|
Cryoem structure of the lbcas12a-crrna-2xacrva1 complex
. SNAP output
|
|
6nmd
|
unknown function-RNA |
cryo-EM (3.49 Å) |
Zhang H, Li Z, Daczkowski CM, Gabel C, Mesecar AD,
Chang L |
(2019) "Structural
Basis for the Inhibition of CRISPR-Cas12a by
Anti-CRISPR Proteins." Cell Host Microbe,
25, 815. doi: 10.1016/j.chom.2019.05.004.
|
cryo-EM structure of the lbcas12a-crrna-acrva1 complex
. SNAP output
|
|
6nme
|
unknown function-RNA |
cryo-EM (5.67 Å) |
Zhang H, Li Z, Daczkowski CM, Gabel C, Mesecar AD,
Chang L |
(2019) "Structural
Basis for the Inhibition of CRISPR-Cas12a by
Anti-CRISPR Proteins." Cell Host Microbe,
25, 815. doi: 10.1016/j.chom.2019.05.004.
|
Structure of lbcas12a-crrna . SNAP output
|
|
6noc
|
RNA binding protein-RNA |
X-ray (2.849 Å) |
Bhat VD, McCann KL, Wang Y, Fonseca DR, Shukla T,
Alexander JC, Qiu C, Wickens M, Lo TW, Tanaka Hall TM,
Campbell ZT |
(2019) "Engineering
a conserved RNA regulatory protein repurposes its
biological function in vivo ." Elife,
8. doi: 10.7554/eLife.43788.
|
Crystal structure of fbf-2 repeat 5 mutant (c363a,
r364y) in complex with 8-nt RNA . SNAP output
|
|
6nod
|
RNA binding protein-RNA |
X-ray (2.547 Å) |
Bhat VD, McCann KL, Wang Y, Fonseca DR, Shukla T,
Alexander JC, Qiu C, Wickens M, Lo TW, Tanaka Hall TM,
Campbell ZT |
(2019) "Engineering
a conserved RNA regulatory protein repurposes its
biological function in vivo ." Elife,
8. doi: 10.7554/eLife.43788.
|
Crystal structure of c. elegans puf-8 in complex with
RNA . SNAP output
|
|
6nof
|
RNA binding protein-RNA |
X-ray (2.251 Å) |
Bhat VD, McCann KL, Wang Y, Fonseca DR, Shukla T,
Alexander JC, Qiu C, Wickens M, Lo TW, Tanaka Hall TM,
Campbell ZT |
(2019) "Engineering
a conserved RNA regulatory protein repurposes its
biological function in vivo ." Elife,
8. doi: 10.7554/eLife.43788.
|
Crystal structure of fbf-2 repeat 5 mutant (c363a,
r364y, q367s) in complex with 8-nt RNA . SNAP output
|
|
6noh
|
RNA binding protein-RNA |
X-ray (2.249 Å) |
Bhat VD, McCann KL, Wang Y, Fonseca DR, Shukla T,
Alexander JC, Qiu C, Wickens M, Lo TW, Tanaka Hall TM,
Campbell ZT |
(2019) "Engineering
a conserved RNA regulatory protein repurposes its
biological function in vivo ." Elife,
8. doi: 10.7554/eLife.43788.
|
Crystal structure of fbf-2 repeat 5 mutant (c363s,
r364y, q367s) in complex with 8-nt RNA . SNAP output
|
|
6nqb
|
ribosome |
cryo-EM (3.8 Å) |
Razi A, Davis JH, Hao Y, Jahagirdar D, Thurlow B,
Basu K, Jain N, Gomez-Blanco J, Britton RA, Vargas J,
Guarne A, Woodson SA, Williamson JR, Ortega J |
(2019) "Role of
Era in assembly and homeostasis of the ribosomal small
subunit." Nucleic Acids Res.,
47, 8301-8317. doi: 10.1093/nar/gkz571.
|
Role of era in assembly and homeostasis of the
ribosomal small subunit . SNAP output
|
|
6nsh
|
ribosome |
X-ray (3.397 Å) |
Hoffer E, Hong S, Sunita S, Maehigashi T, Gonzalez
Jnr RL, Whitford P, Dunham CM |
(2020) "Structural
insights into mRNA reading frame regulation by tRNA
modification and slippery codon-anticodon pairing."
Elife, 9. doi: 10.7554/eLife.51898.
|
Modified asl proline bound to thermus thermophilus 70s
(near-cognate) . SNAP
output
|
|
6nta
|
ribosome |
X-ray (3.1 Å) |
Hoffer E, Hong S, Sunita S, Maehigashi T, Gonzalez
Jnr RL, Whitford P, Dunham CM |
(2020) "Structural
insights into mRNA reading frame regulation by tRNA
modification and slippery codon-anticodon pairing."
Elife, 9. doi: 10.7554/eLife.51898.
|
Modified asl proline bound to thermus thermophilus 70s
(cognate) . SNAP
output
|
|
6nu2
|
ribosome |
cryo-EM (3.9 Å) |
Koripella RK, Sharma MR, Risteff P, Keshavan P,
Agrawal RK |
(2019) "Structural
insights into unique features of the human
mitochondrial ribosome recycling."
Proc.Natl.Acad.Sci.USA, 116,
8283-8288. doi: 10.1073/pnas.1815675116.
|
Structural insights into unique features of the human
mitochondrial ribosome recycling . SNAP output
|
|
6nu3
|
ribosome |
cryo-EM (4.4 Å) |
Koripella RK, Sharma MR, Risteff P, Keshavan P,
Agrawal RK |
(2019) "Structural
insights into unique features of the human
mitochondrial ribosome recycling."
Proc.Natl.Acad.Sci.USA, 116,
8283-8288. doi: 10.1073/pnas.1815675116.
|
Structural insights into unique features of the human
mitochondrial ribosome recycling . SNAP output
|
|
6nud
|
hydrolase,transferase-RNA |
cryo-EM (3.5 Å) |
Guo M, Zhang K, Zhu Y, Pintilie GD, Guan X, Li S,
Schmid MF, Ma Z, Chiu W, Huang Z |
(2019) "Coupling
of ssRNA cleavage with DNase activity in type III-A
CRISPR-Csm revealed by cryo-EM and biochemistry."
Cell Res., 29, 305-312. doi:
10.1038/s41422-019-0151-x.
|
Small conformation of ssrna-bound crispr_csm complex .
SNAP output
|
|
6nue
|
hydrolase,transferase-RNA |
cryo-EM (3.3 Å) |
Guo M, Zhang K, Zhu Y, Pintilie GD, Guan X, Li S,
Schmid MF, Ma Z, Chiu W, Huang Z |
(2019) "Coupling
of ssRNA cleavage with DNase activity in type III-A
CRISPR-Csm revealed by cryo-EM and biochemistry."
Cell Res., 29, 305-312. doi:
10.1038/s41422-019-0151-x.
|
Small conformation of apo crispr_csm complex . SNAP output
|
|
6nuo
|
ribosome |
X-ray (3.2 Å) |
Hoffer E, Hong S, Sunita S, Maehigashi T, Gonzalez
Jnr RL, Whitford P, Dunham CM |
(2020) "Structural
insights into mRNA reading frame regulation by tRNA
modification and slippery codon-anticodon pairing."
Elife, 9. doi: 10.7554/eLife.51898.
|
Modified trna(pro) bound to thermus thermophilus 70s
(cognate) . SNAP
output
|
|
6nut
|
viral protein-RNA |
cryo-EM (3.1 Å) |
Kirchdoerfer RN, Saphire EO, Ward AB |
(2019) "Cryo-EM
structure of the Ebola virus nucleoprotein-RNA
complex." Acta Crystallogr.,Sect.F,
75, 340-347. doi: 10.1107/S2053230X19004424.
|
Ebola virus nucleoprotein - RNA complex . SNAP output
|
|
6nwy
|
ribosome |
X-ray (3.5 Å) |
Hoffer E, Hong S, Sunita S, Maehigashi T, Gonzalez
Jnr RL, Whitford P, Dunham CM |
(2020) "Structural
insights into mRNA reading frame regulation by tRNA
modification and slippery codon-anticodon pairing."
Elife, 9. doi: 10.7554/eLife.51898.
|
Modified trna(pro) bound to thermus thermophilus 70s
(near-cognate) . SNAP
output
|
|
6ny5
|
RNA binding protein-RNA |
X-ray (3.002 Å) |
Qiu C, Dutcher RC, Porter DF, Arava Y, Wickens M,
Hall TMT |
(2019) "Distinct
RNA-binding modules in a single PUF protein cooperate
to determine RNA specificity." Nucleic Acids
Res., 47, 8770-8784. doi:
10.1093/nar/gkz583.
|
Crystal structure of the pum-hd domain of s. pombe puf1
in complex with RNA . SNAP output
|
|
6ny6
|
ribosome |
X-ray (3.74 Å) |
Pavelich IJ, Maehigashi T, Hoffer ED, Ruangprasert A,
Miles SJ, Dunham CM |
(2019) "Monomeric
YoeB toxin retains RNase activity but adopts an
obligate dimeric form for thermal stability."
Nucleic Acids Res., 47,
10400-10413. doi: 10.1093/nar/gkz760.
|
Structure of dimeric escherichia coli toxin yoeb bound
to the thermus thermophilus 30s ribosome . SNAP output
|
|
6o16
|
hydrolase-RNA |
X-ray (2.875 Å) |
Boneberg FM, Brandmann T, Kobel L, van den Heuvel J,
Bargsten K, Bammert L, Kutay U, Jinek M |
(2019) "Molecular
mechanism of the RNA helicase DHX37 and its activation
by UTP14A in ribosome biogenesis." Rna,
25, 685-701. doi: 10.1261/rna.069609.118.
|
Crystal structure of murine dhx37 in complex with RNA .
SNAP output
|
|
6o1k
|
RNA binding protein-RNA-hydrolase |
cryo-EM (3.13 Å) |
Pei XY, Dendooven T, Sonnleitner E, Chen S, Blasi U,
Luisi BF |
(2019) "Architectural
principles for Hfq/Crc-mediated regulation of gene
expression." Elife, 8.
doi: 10.7554/eLife.43158.
|
Architectural principles for hfq-crc-mediated
regulation of gene expression. hfq-crc-amie 2:2:2
complex (core complex) . SNAP output
|
|
6o1l
|
RNA binding protein-RNA-hydrolase |
cryo-EM (3.37 Å) |
Pei XY, Dendooven T, Sonnleitner E, Chen S, Blasi U,
Luisi BF |
(2019) "Architectural
principles for Hfq/Crc-mediated regulation of gene
expression." Elife, 8.
doi: 10.7554/eLife.43158.
|
Architectural principles for hfq-crc-mediated
regulation of gene expression hfq-crc-amie 2:3:2
complex . SNAP
output
|
|
6o1m
|
RNA binding protein-RNA-hydrolase |
cryo-EM (3.15 Å) |
Pei XY, Dendooven T, Sonnleitner E, Chen S, Blasi U,
Luisi BF |
(2019) "Architectural
principles for Hfq/Crc-mediated regulation of gene
expression." Elife, 8.
doi: 10.7554/eLife.43158.
|
Architectural principles for hfq-crc-mediated
regulation of gene expression. hfq-crc-amie 2:4:2
complex . SNAP
output
|
|
6o1o
|
RNA binding protein-RNA |
cryo-EM (3.8 Å) |
Liu TY, Liu JJ, Aditham AJ, Nogales E, Doudna JA |
(2019) "Target
preference of Type III-A CRISPR-Cas complexes at the
transcription bubble." Nat Commun,
10, 3001. doi: 10.1038/s41467-019-10780-2.
|
cryo-EM structure of the t. thermophilus csm complex
bound to target ssrna . SNAP output
|
|
6o3m
|
ribosome |
X-ray (3.97 Å) |
Hoffer E, Hong S, Sunita S, Maehigashi T, Gonzalez
Jnr RL, Whitford P, Dunham CM |
(2020) "Structural
insights into mRNA reading frame regulation by tRNA
modification and slippery codon-anticodon pairing."
Elife, 9. doi: 10.7554/eLife.51898.
|
Unmodified trna(pro) bound to thermus thermophilus 70s
(cognate) . SNAP
output
|
|
6o5f
|
hydrolase-RNA |
X-ray (2.504 Å) |
Song H, Ji X |
(2019) "The
mechanism of RNA duplex recognition and unwinding by
DEAD-box helicase DDX3X." Nat Commun,
10, 3085. doi: 10.1038/s41467-019-11083-2.
|
Crystal structure of dead-box RNA helicase ddx3x at
pre-unwound state . SNAP
output
|
|
6o6v
|
immune system-RNA |
X-ray (2.35 Å) |
Jia N, Jones R, Yang G, Ouerfelli O, Patel DJ |
(2019) "CRISPR-Cas
III-A Csm6 CARF Domain Is a Ring Nuclease Triggering
Stepwise cA4Cleavage with ApA>p Formation
Terminating RNase Activity." Mol.Cell,
75, 944-956.e6. doi: 10.1016/j.molcel.2019.06.014.
|
Crystal structure of csm6 in complex with ca4 by
soaking ca4 into csm6 . SNAP output
|
|
6o6x
|
immune system-RNA |
X-ray (2.11 Å) |
Jia N, Jones R, Yang G, Ouerfelli O, Patel DJ |
(2019) "CRISPR-Cas
III-A Csm6 CARF Domain Is a Ring Nuclease Triggering
Stepwise cA4Cleavage with ApA>p Formation
Terminating RNase Activity." Mol.Cell,
75, 944-956.e6. doi: 10.1016/j.molcel.2019.06.014.
|
Crystal structure of csm6 w14a-e337a mutant in complex
with ca4 by cocrystallization . SNAP output
|
|
6o75
|
immune system-RNA |
X-ray (2.6 Å) |
Jia N, Jones R, Sukenick G, Patel DJ |
(2019) "Second
Messenger cA4Formation within the Composite Csm1 Palm
Pocket of Type III-A CRISPR-Cas Csm Complex and Its
Release Path." Mol.Cell,
75, 933-943.e6. doi: 10.1016/j.molcel.2019.06.013.
|
Crystal structure of csm1-csm4 cassette in complex with
pppapa . SNAP output
|
|
6o78
|
immune system-RNA |
X-ray (2.8 Å) |
Jia N, Jones R, Sukenick G, Patel DJ |
(2019) "Second
Messenger cA4Formation within the Composite Csm1 Palm
Pocket of Type III-A CRISPR-Cas Csm Complex and Its
Release Path." Mol.Cell,
75, 933-943.e6. doi: 10.1016/j.molcel.2019.06.013.
|
Crystal structure of csm1-csm4 cassette in complex with
pppapapa . SNAP
output
|
|
6o79
|
immune sytem-RNA |
X-ray (3.0 Å) |
Jia N, Jones R, Sukenick G, Patel DJ |
(2019) "Second
Messenger cA4Formation within the Composite Csm1 Palm
Pocket of Type III-A CRISPR-Cas Csm Complex and Its
Release Path." Mol.Cell,
75, 933-943.e6. doi: 10.1016/j.molcel.2019.06.013.
|
Crystal structure of csm1-csm4 cassette in complex with
ca3 . SNAP output
|
|
6o7b
|
immune system-RNA |
X-ray (2.4 Å) |
Jia N, Jones R, Sukenick G, Patel DJ |
(2019) "Second
Messenger cA4Formation within the Composite Csm1 Palm
Pocket of Type III-A CRISPR-Cas Csm Complex and Its
Release Path." Mol.Cell,
75, 933-943.e6. doi: 10.1016/j.molcel.2019.06.013.
|
Crystal structure of csm1-csm4 cassette in complex with
ca4 . SNAP output
|
|
6o7e
|
immune system-RNA |
cryo-EM (3.2 Å) |
Jia N, Jones R, Sukenick G, Patel DJ |
(2019) "Second
Messenger cA4Formation within the Composite Csm1 Palm
Pocket of Type III-A CRISPR-Cas Csm Complex and Its
Release Path." Mol.Cell,
75, 933-943.e6. doi: 10.1016/j.molcel.2019.06.013.
|
cryo-EM structure of csm-crrna-target RNA ternary
complex in complex with amppnp in type iii-a crispr-cas
system . SNAP output
|
|
6o7h
|
immune system-RNA-DNA |
cryo-EM (2.9 Å) |
Jia N, Jones R, Sukenick G, Patel DJ |
(2019) "Second
Messenger cA4Formation within the Composite Csm1 Palm
Pocket of Type III-A CRISPR-Cas Csm Complex and Its
Release Path." Mol.Cell,
75, 933-943.e6. doi: 10.1016/j.molcel.2019.06.013.
|
cryo-EM structure of csm-crrna-target RNA ternary
complex in complex with ca4 in type iii-a crispr-cas
system . SNAP output
|
|
6o7i
|
immune system-RNA |
cryo-EM (3.2 Å) |
Jia N, Jones R, Sukenick G, Patel DJ |
(2019) "Second
Messenger cA4Formation within the Composite Csm1 Palm
Pocket of Type III-A CRISPR-Cas Csm Complex and Its
Release Path." Mol.Cell,
75, 933-943.e6. doi: 10.1016/j.molcel.2019.06.013.
|
cryo-EM structure of csm-crrna-target RNA ternary
bigger complex in complex with ca4 in type iii-a
crispr-cas system . SNAP
output
|
|
6o7k
|
ribosome |
cryo-EM (4.2 Å) |
Kaledhonkar S, Fu Z, Caban K, Li W, Chen B, Sun M,
Gonzalez Jr RL, Frank J |
(2019) "Late
steps in bacterial translation initiation visualized
using time-resolved cryo-EM." Nature,
570, 400-404. doi: 10.1038/s41586-019-1249-5.
|
30s initiation complex . SNAP output
|
|
6o8w
|
ribosome |
cryo-EM (3.53 Å) |
Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory
ST, Murray BE, Krause KL, Khayat R, Jogl G |
(2020) "Cryo-electron
microscopy structure of the 70S ribosome from
Enterococcus faecalis." Sci Rep,
10, 16301. doi: 10.1038/s41598-020-73199-6.
|
cryo-EM image reconstruction of the 70s ribosome
enterococcus faecalis class01 . SNAP output
|
|
6o8x
|
ribosome |
cryo-EM (3.68 Å) |
Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory
ST, Murray BE, Krause KL, Khayat R, Jogl G |
(2020) "Cryo-electron
microscopy structure of the 70S ribosome from
Enterococcus faecalis." Sci Rep,
10, 16301. doi: 10.1038/s41598-020-73199-6.
|
cryo-EM image reconstruction of the 70s ribosome
enterococcus faecalis class02 . SNAP output
|
|
6o8y
|
ribosome |
cryo-EM (4.14 Å) |
Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory
ST, Murray BE, Krause KL, Khayat R, Jogl G |
(2020) "Cryo-electron
microscopy structure of the 70S ribosome from
Enterococcus faecalis." Sci Rep,
10, 16301. doi: 10.1038/s41598-020-73199-6.
|
cryo-EM image reconstruction of the 70s ribosome
enterococcus faecalis class03 . SNAP output
|
|
6o8z
|
ribosome |
cryo-EM (3.49 Å) |
Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory
ST, Murray BE, Krause KL, Khayat R, Jogl G |
(2020) "Cryo-electron
microscopy structure of the 70S ribosome from
Enterococcus faecalis." Sci Rep,
10, 16301. doi: 10.1038/s41598-020-73199-6.
|
cryo-EM image reconstruction of the 70s ribosome
enterococcus faecalis class04 . SNAP output
|
|
6o90
|
ribosome |
cryo-EM (3.49 Å) |
Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory
ST, Murray BE, Krause KL, Khayat R, Jogl G |
(2020) "Cryo-electron
microscopy structure of the 70S ribosome from
Enterococcus faecalis." Sci Rep,
10, 16301. doi: 10.1038/s41598-020-73199-6.
|
cryo-EM image reconstruction of the 70s ribosome
enterococcus faecalis class05 . SNAP output
|
|
6o97
|
ribosome-antibiotic |
X-ray (2.75 Å) |
Matsushita T, Sati GC, Kondasinghe N, Pirrone MG,
Kato T, Waduge P, Kumar HS, Sanchon AC, Dobosz-Bartoszek
M, Shcherbakov D, Juhas M, Hobbie SN, Schrepfer T, Chow
CS, Polikanov YS, Schacht J, Vasella A, Bottger EC, Crich
D |
(2019) "Design,
Multigram Synthesis, and in Vitro and in Vivo
Evaluation of Propylamycin: A Semisynthetic
4,5-Deoxystreptamine Class Aminoglycoside for the
Treatment of Drug-Resistant Enterobacteriaceae and
Other Gram-Negative Pathogens." J. Am. Chem.
Soc., 141, 5051-5061. doi:
10.1021/jacs.9b01693.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with propylamycin and bound to mrna
and a-, p-, and e-site trnas at 2.75a resolution .
SNAP output
|
|
6o9j
|
ribosome |
cryo-EM (3.9 Å) |
Kaledhonkar S, Fu Z, Caban K, Li W, Chen B, Sun M,
Gonzalez Jr RL, Frank J |
(2019) "Late
steps in bacterial translation initiation visualized
using time-resolved cryo-EM." Nature,
570, 400-404. doi: 10.1038/s41586-019-1249-5.
|
70s elongation competent ribosome . SNAP output
|
|
6o9k
|
ribosome |
cryo-EM (4.0 Å) |
Kaledhonkar S, Fu Z, Caban K, Li W, Chen B, Sun M,
Gonzalez Jr RL, Frank J |
(2019) "Late
steps in bacterial translation initiation visualized
using time-resolved cryo-EM." Nature,
570, 400-404. doi: 10.1038/s41586-019-1249-5.
|
70s initiation complex . SNAP output
|
|
6of1
|
ribosome |
X-ray (2.8 Å) |
Khabibullina NF, Tereshchenkov AG, Komarova ES,
Syroegin EA, Shiriaev DI, Paleskava A, Kartsev VG,
Bogdanov AA, Konevega AL, Dontsova OA, Sergiev PV,
Osterman IA, Polikanov YS |
(2019) "Structure
of Dirithromycin Bound to the Bacterial Ribosome
Suggests New Ways for Rational Improvement of
Macrolides." Antimicrob.Agents Chemother.,
63. doi: 10.1128/AAC.02266-18.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with dirithromycin and bound to
mrna and a-, p-, and e-site trnas at 2.80a resolution .
SNAP output
|
|
6of6
|
ribosome |
X-ray (3.2 Å) |
Nguyen HA, Sunita S, Dunham CM |
(2020) "Disruption
of evolutionarily correlated tRNA elements impairs
accurate decoding."
Proc.Natl.Acad.Sci.USA, 117,
16333-16338. doi: 10.1073/pnas.2004170117.
|
Crystal structure of trna^ ala(ggc) bound to cognate
70s a-site . SNAP
output
|
|
6ofx
|
ribosome |
cryo-EM (3.3 Å) |
Svidritskiy E, Demo G, Loveland AB, Xu C, Korostelev
AA |
(2019) "Extensive
ribosome and RF2 rearrangements during translation
termination." Elife, 8.
doi: 10.7554/eLife.46850.
|
Non-rotated ribosome (structure i) . SNAP output
|
|
6og7
|
ribosome |
cryo-EM (3.3 Å) |
Svidritskiy E, Demo G, Loveland AB, Xu C, Korostelev
AA |
(2019) "Extensive
ribosome and RF2 rearrangements during translation
termination." Elife, 8.
doi: 10.7554/eLife.46850.
|
70s termination complex with rf2 bound to the uga
codon. non-rotated ribosome with rf2 bound (structure
ii) . SNAP output
|
|
6ogf
|
ribosome |
cryo-EM (3.9 Å) |
Svidritskiy E, Demo G, Loveland AB, Xu C, Korostelev
AA |
(2019) "Extensive
ribosome and RF2 rearrangements during translation
termination." Elife, 8.
doi: 10.7554/eLife.46850.
|
70s termination complex with rf2 bound to the uga
codon. partially rotated ribosome with rf2 bound
(structure iii). . SNAP
output
|
|
6ogg
|
ribosome |
cryo-EM (4.2 Å) |
Svidritskiy E, Demo G, Loveland AB, Xu C, Korostelev
AA |
(2019) "Extensive
ribosome and RF2 rearrangements during translation
termination." Elife, 8.
doi: 10.7554/eLife.46850.
|
70s termination complex with rf2 bound to the uga
codon. rotated ribosome with rf2 bound (structure iv).
. SNAP output
|
|
6ogi
|
ribosome |
cryo-EM (3.4 Å) |
Svidritskiy E, Demo G, Loveland AB, Xu C, Korostelev
AA |
(2019) "Extensive
ribosome and RF2 rearrangements during translation
termination." Elife, 8.
doi: 10.7554/eLife.46850.
|
70s termination complex with rf2 bound to the uag
codon. rotated ribosome conformation (structure v) .
SNAP output
|
|
6ogy
|
viral protein-transferase-RNA |
cryo-EM (3.4 Å) |
Ding K, Celma CC, Zhang X, Chang T, Shen W, Atanasov
I, Roy P, Zhou ZH |
(2019) "In situ
structures of rotavirus polymerase in action and
mechanism of mRNA transcription and release."
Nat Commun, 10, 2216. doi:
10.1038/s41467-019-10236-7.
|
In situ structure of rotavirus RNA-dependent RNA
polymerase at duplex-open state . SNAP output
|
|
6ogz
|
viral protein-RNA-transferase |
cryo-EM (3.6 Å) |
Ding K, Celma CC, Zhang X, Chang T, Shen W, Atanasov
I, Roy P, Zhou ZH |
(2019) "In situ
structures of rotavirus polymerase in action and
mechanism of mRNA transcription and release."
Nat Commun, 10, 2216. doi:
10.1038/s41467-019-10236-7.
|
In situ structure of rotavirus RNA-dependent RNA
polymerase at transcript-elongated state . SNAP output
|
|
6oig
|
ribosome |
cryo-EM (3.8 Å) |
Rai J, Parker MD, Huang H, Choy S, Ghalei H, Johnson
MC, Karbstein K, Stroupe ME |
(2021) "An open
interface in the pre-80S ribosome coordinated by
ribosome assembly factors Tsr1 and Dim1 enables
temporal regulation of Fap7." Rna,
27, 221-233. doi: 10.1261/rna.077610.120.
|
Subunit joining exposes nascent pre-40s rrna for
processing and quality control . SNAP output
|
|
6oj2
|
ribosome |
X-ray (3.2 Å) |
Nguyen HA, Sunita S, Dunham CM |
(2020) "Disruption
of evolutionarily correlated tRNA elements impairs
accurate decoding."
Proc.Natl.Acad.Sci.USA, 117,
16333-16338. doi: 10.1073/pnas.2004170117.
|
Crystal structure of trna^ ala(ggc) bound to the
near-cognate 70s a-site . SNAP output
|
|
6oj6
|
viral protein-transferase-RNA |
cryo-EM (4.2 Å) |
Jenni S, Salgado EN, Herrmann T, Li Z, Grant T,
Grigorieff N, Trapani S, Estrozi LF, Harrison SC |
(2019) "In situ
Structure of Rotavirus VP1 RNA-Dependent RNA
Polymerase." J.Mol.Biol.,
431, 3124-3138. doi: 10.1016/j.jmb.2019.06.016.
|
In situ structure of rotavirus vp1 RNA-dependent RNA
polymerase (dlp_rna) . SNAP output
|
|
6okk
|
ribosome-inhibitor |
cryo-EM (3.3 Å) |
Wong W, Bai XC, Brown A, Fernandez IS, Hanssen E,
Condron M, Tan YH, Baum J, Scheres SH |
(2014) "Cryo-EM
structure of the Plasmodium falciparum 80S ribosome
bound to the anti-protozoan drug emetine."
Elife, 3. doi: 10.7554/eLife.03080.
|
cryo-EM structure of the plasmodium falciparum 80s
ribosome bound to the anti-protozoan drug emetine,
small subunit . SNAP
output
|
|
6olg
|
ribosome |
cryo-EM (3.4 Å) |
Li W, Ward FR, McClure KF, Chang ST, Montabana E,
Liras S, Dullea RG, Cate JHD |
(2019) "Structural
basis for selective stalling of human ribosome nascent
chain complexes by a drug-like molecule."
Nat.Struct.Mol.Biol., 26,
501-509. doi: 10.1038/s41594-019-0236-8.
|
Human ribosome nascent chain complex stalled by a
drug-like small molecule (cdh1_rnc with pp trna) .
SNAP output
|
|
6olz
|
ribosome |
cryo-EM (3.9 Å) |
Li W, Ward FR, McClure KF, Chang ST, Montabana E,
Liras S, Dullea RG, Cate JHD |
(2019) "Structural
basis for selective stalling of human ribosome nascent
chain complexes by a drug-like molecule."
Nat.Struct.Mol.Biol., 26,
501-509. doi: 10.1038/s41594-019-0236-8.
|
Human ribosome nascent chain complex (pcsk9-rnc)
stalled by a drug-like molecule with pp trna . SNAP output
|
|
6om6
|
ribosome |
cryo-EM (3.1 Å) |
Aron ZD, Mehrani A, Hoffer ED, Connolly KL, Srinivas
P, Torhan MC, Alumasa JN, Cabrera M, Hosangadi D, Barbor
JS, Cardinale SC, Kwasny SM, Morin LR, Butler MM,
Opperman TJ, Bowlin TL, Jerse A, Stagg SM, Dunham CM,
Keiler KC |
(2021) "trans-Translation
inhibitors bind to a novel site on the ribosome and
clear Neisseria gonorrhoeae in vivo." Nat
Commun, 12, 1799. doi: 10.1038/s41467-021-22012-7.
|
Structure of trans-translation inhibitor bound to e.
coli 70s ribosome with p site trna . SNAP output
|
|
6oon
|
hydrolase-RNA |
X-ray (1.9 Å) |
Park MS, Araya-Secchi R, Brackbill JA, Phan HD,
Kehling AC, Abd El-Wahab EW, Dayeh DM, Sotomayor M,
Nakanishi K |
(2019) "Multidomain
Convergence of Argonaute during RISC Assembly
Correlates with the Formation of Internal Water
Clusters." Mol.Cell, 75,
725-740.e6. doi: 10.1016/j.molcel.2019.06.011.
|
Human argonaute4 bound to guide RNA . SNAP output
|
|
6ope
|
ribosome |
X-ray (3.1 Å) |
Nguyen HA, Sunita S, Dunham CM |
(2020) "Disruption
of evolutionarily correlated tRNA elements impairs
accurate decoding."
Proc.Natl.Acad.Sci.USA, 117,
16333-16338. doi: 10.1073/pnas.2004170117.
|
Crystal structure of trna^ ala(ggc) u32-a38 bound to
near-cognate 70s a site . SNAP output
|
|
6ord
|
ribosome |
X-ray (3.1 Å) |
Nguyen HA, Sunita S, Dunham CM |
(2020) "Disruption
of evolutionarily correlated tRNA elements impairs
accurate decoding."
Proc.Natl.Acad.Sci.USA, 117,
16333-16338. doi: 10.1073/pnas.2004170117.
|
Crystal structure of trna^ ala(ggc) u32-a38 bound to
cognate 70s a site . SNAP output
|
|
6ore
|
ribosome |
cryo-EM (2.9 Å) |
Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M,
Chen B, Grassucci RA, Ehrenberg M, Frank J |
(2019) "The
structural basis for release-factor activation during
translation termination revealed by time-resolved
cryogenic electron microscopy." Nat
Commun, 10, 2579. doi: 10.1038/s41467-019-10608-z.
|
Release complex 70s . SNAP output
|
|
6orl
|
ribosome |
cryo-EM (3.5 Å) |
Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M,
Chen B, Grassucci RA, Ehrenberg M, Frank J |
(2019) "The
structural basis for release-factor activation during
translation termination revealed by time-resolved
cryogenic electron microscopy." Nat
Commun, 10, 2579. doi: 10.1038/s41467-019-10608-z.
|
Rf1 pre-accommodated 70s complex at 24 ms . SNAP output
|
|
6osi
|
ribosome |
X-ray (4.14 Å) |
Hoffer E, Hong S, Sunita S, Maehigashi T, Gonzalez
Jnr RL, Whitford P, Dunham CM |
(2020) "Structural
insights into mRNA reading frame regulation by tRNA
modification and slippery codon-anticodon pairing."
Elife, 9. doi: 10.7554/eLife.51898.
|
Unmodified trna(pro) bound to thermus thermophilus 70s
(near cognate) . SNAP
output
|
|
6osk
|
ribosome |
cryo-EM (3.6 Å) |
Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M,
Chen B, Grassucci RA, Ehrenberg M, Frank J |
(2019) "The
structural basis for release-factor activation during
translation termination revealed by time-resolved
cryogenic electron microscopy." Nat
Commun, 10, 2579. doi: 10.1038/s41467-019-10608-z.
|
Rf1 accommodated 70s complex at 60 ms . SNAP output
|
|
6osq
|
ribosome |
cryo-EM (3.5 Å) |
Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M,
Chen B, Grassucci RA, Ehrenberg M, Frank J |
(2019) "The
structural basis for release-factor activation during
translation termination revealed by time-resolved
cryogenic electron microscopy." Nat
Commun, 10, 2579. doi: 10.1038/s41467-019-10608-z.
|
Rf1 accommodated state bound release complex 70s at
long incubation time point . SNAP output
|
|
6ost
|
ribosome |
cryo-EM (4.2 Å) |
Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M,
Chen B, Grassucci RA, Ehrenberg M, Frank J |
(2019) "The
structural basis for release-factor activation during
translation termination revealed by time-resolved
cryogenic electron microscopy." Nat
Commun, 10, 2579. doi: 10.1038/s41467-019-10608-z.
|
Rf2 pre-accommodated state bound release complex 70s at
24ms . SNAP output
|
|
6ot3
|
ribosome |
cryo-EM (3.9 Å) |
Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M,
Chen B, Grassucci RA, Ehrenberg M, Frank J |
(2019) "The
structural basis for release-factor activation during
translation termination revealed by time-resolved
cryogenic electron microscopy." Nat
Commun, 10, 2579. doi: 10.1038/s41467-019-10608-z.
|
Rf2 accommodated state bound release complex 70s at 24
ms . SNAP output
|
|
6otr
|
ribosome |
X-ray (3.12 Å) |
Pavelich IJ, Maehigashi T, Hoffer ED, Ruangprasert A,
Miles SJ, Dunham CM |
(2019) "Monomeric
YoeB toxin retains RNase activity but adopts an
obligate dimeric form for thermal stability."
Nucleic Acids Res., 47,
10400-10413. doi: 10.1093/nar/gkz760.
|
Dimeric e.coli yoeb bound to thermus thermophilus 70s
post-cleavage (aau) . SNAP output
|
|
6ouo
|
ribosome |
cryo-EM (3.7 Å) |
Fu Z, Indrisiunaite G, Kaledhonkar S, Shah B, Sun M,
Chen B, Grassucci RA, Ehrenberg M, Frank J |
(2019) "The
structural basis for release-factor activation during
translation termination revealed by time-resolved
cryogenic electron microscopy." Nat
Commun, 10, 2579. doi: 10.1038/s41467-019-10608-z.
|
Rf2 accommodated state bound 70s complex at long
incubation time . SNAP
output
|
|
6ov0
|
immune system-RNA |
X-ray (2.8 Å) |
Jia N, Jones R, Yang G, Ouerfelli O, Patel DJ |
(2019) "CRISPR-Cas
III-A Csm6 CARF Domain Is a Ring Nuclease Triggering
Stepwise cA4Cleavage with ApA>p Formation
Terminating RNase Activity." Mol.Cell,
75, 944-956.e6. doi: 10.1016/j.molcel.2019.06.014.
|
Crystal structure of csm6 in complex with a4>p by
soaking a4>p into csm6 . SNAP output
|
|
6oxa
|
ribosome |
X-ray (3.25 Å) |
Pavelich IJ, Maehigashi T, Hoffer ED, Ruangprasert A,
Miles SJ, Dunham CM |
(2019) "Monomeric
YoeB toxin retains RNase activity but adopts an
obligate dimeric form for thermal stability."
Nucleic Acids Res., 47,
10400-10413. doi: 10.1093/nar/gkz760.
|
Dimeric e.coli yoeb bound to thermus thermophilus 70s
pre-cleavage (aau) . SNAP output
|
|
6oxi
|
ribosome |
X-ray (3.495 Å) |
Pavelich IJ, Maehigashi T, Hoffer ED, Ruangprasert A,
Miles SJ, Dunham CM |
(2019) "Monomeric
YoeB toxin retains RNase activity but adopts an
obligate dimeric form for thermal stability."
Nucleic Acids Res., 47,
10400-10413. doi: 10.1093/nar/gkz760.
|
Dimeric e.coli yoeb bound to thermus thermophilus 70s
post-cleavage (uaa) . SNAP output
|
|
6ozj
|
hydrolase |
X-ray (2.247 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
in complex with a 23mer RNA oligo containing an inosine
in the absence of divalent cation . SNAP output
|
|
6ozk
|
hydrolase |
X-ray (2.104 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
in complex with a 23mer RNA oligo containing an inosine
after 68h soak in ca2+ . SNAP output
|
|
6ozl
|
hydrolase |
X-ray (2.1 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
in complex with a 23mer RNA oligo containing an inosine
after a 2 min soak in mn2+ . SNAP output
|
|
6ozm
|
hydrolase-RNA |
X-ray (2.15 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
in complex with a 23mer RNA oligo containing an inosine
after a 10 min soak in 10 mm mn2+ . SNAP output
|
|
6ozn
|
hydrolase-RNA |
X-ray (1.9 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
in complex with a 23mer RNA oligo containing an inosine
after a 15 min soak in 10 mm mn2+ . SNAP output
|
|
6ozo
|
hydrolase-RNA |
X-ray (2.235 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
in complex with a 23mer RNA oligo containing an inosine
after a 30 min soak in 10 mm mn2+ . SNAP output
|
|
6ozp
|
hydrolase-RNA |
X-ray (1.96 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
in complex with a 23mer RNA oligo containing an inosine
after a 180 min soak in 10 mm mn2+ . SNAP output
|
|
6ozq
|
hydrolase |
X-ray (2.153 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
(k155m) in complex with a 23mer RNA oligo containing an
inosine after a 100 min soak in 10 mm mn2+ and k+ .
SNAP output
|
|
6ozr
|
hydrolase |
X-ray (2.15 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
in complex with a 23mer RNA oligo containing an inosine
after a 15 min soak in 10 mm mg2+ . SNAP output
|
|
6ozs
|
hydrolase-RNA |
X-ray (2.41 Å) |
Wu J, Samara NL, Kuraoka I, Yang W |
(2019) "Evolution
of Inosine-Specific Endonuclease V from Bacterial DNase
to Eukaryotic RNase." Mol.Cell,
76, 44. doi: 10.1016/j.molcel.2019.06.046.
|
Crystal structure of mus musculus (mm) endonuclease v
in complex with a 23mer RNA oligo containing an inosine
after a 90 min soak in 10 mm mg2+ . SNAP output
|
|
6p4g
|
ribosome |
cryo-EM (3.1 Å) |
Acosta-Reyes F, Neupane R, Frank J, Fernandez IS |
(2019) "The
Israeli acute paralysis virus IRES captures host
ribosomes by mimicking a ribosomal state with hybrid
tRNAs." Embo J., 38,
e102226. doi: 10.15252/embj.2019102226.
|
Structure of a mammalian small ribosomal subunit in
complex with the israeli acute paralysis virus ires
(class 1) . SNAP
output
|
|
6p4h
|
ribosome |
cryo-EM (3.2 Å) |
Acosta-Reyes F, Neupane R, Frank J, Fernandez IS |
(2019) "The
Israeli acute paralysis virus IRES captures host
ribosomes by mimicking a ribosomal state with hybrid
tRNAs." Embo J., 38,
e102226. doi: 10.15252/embj.2019102226.
|
Structure of a mammalian small ribosomal subunit in
complex with the israeli acute paralysis virus ires
(class 2) . SNAP
output
|
|
6p5i
|
ribosome |
cryo-EM (3.1 Å) |
Acosta-Reyes F, Neupane R, Frank J, Fernandez IS |
(2019) "The
Israeli acute paralysis virus IRES captures host
ribosomes by mimicking a ribosomal state with hybrid
tRNAs." Embo J., 38,
e102226. doi: 10.15252/embj.2019102226.
|
Structure of a mammalian 80s ribosome in complex with
the israeli acute paralysis virus ires (class 1) .
SNAP output
|
|
6p5j
|
ribosome |
cryo-EM (3.1 Å) |
Acosta-Reyes F, Neupane R, Frank J, Fernandez IS |
(2019) "The
Israeli acute paralysis virus IRES captures host
ribosomes by mimicking a ribosomal state with hybrid
tRNAs." Embo J., 38,
e102226. doi: 10.15252/embj.2019102226.
|
Structure of a mammalian 80s ribosome in complex with
the israeli acute paralysis virus ires (class 2) .
SNAP output
|
|
6p5k
|
ribosome |
cryo-EM (3.1 Å) |
Acosta-Reyes F, Neupane R, Frank J, Fernandez IS |
(2019) "The
Israeli acute paralysis virus IRES captures host
ribosomes by mimicking a ribosomal state with hybrid
tRNAs." Embo J., 38,
e102226. doi: 10.15252/embj.2019102226.
|
Structure of a mammalian 80s ribosome in complex with
the israeli acute paralysis virus ires (class 3) .
SNAP output
|
|
6p5n
|
ribosome |
cryo-EM (3.2 Å) |
Acosta-Reyes F, Neupane R, Frank J, Fernandez IS |
(2019) "The
Israeli acute paralysis virus IRES captures host
ribosomes by mimicking a ribosomal state with hybrid
tRNAs." Embo J., 38,
e102226. doi: 10.15252/embj.2019102226.
|
Structure of a mammalian 80s ribosome in complex with a
single translocated israeli acute paralysis virus ires
and erf1 . SNAP
output
|
|
6p7m
|
RNA binding protein-RNA |
cryo-EM (3.0 Å) |
Knott GJ, Cress BF, Liu JJ, Thornton BW, Lew RJ,
Al-Shayeb B, Rosenberg DJ, Hammel M, Adler BA, Lobba MJ,
Xu M, Arkin AP, Fellmann C, Doudna JA |
(2019) "Structural
basis for AcrVA4 inhibition of specific
CRISPR-Cas12a." Elife, 8.
doi: 10.7554/eLife.49110.
|
cryo-EM structure of lbcas12a-crrna: acrva4 (1:2
complex) . SNAP
output
|
|
6p7n
|
RNA binding protein-RNA |
cryo-EM (4.9 Å) |
Knott GJ, Cress BF, Liu JJ, Thornton BW, Lew RJ,
Al-Shayeb B, Rosenberg DJ, Hammel M, Adler BA, Lobba MJ,
Xu M, Arkin AP, Fellmann C, Doudna JA |
(2019) "Structural
basis for AcrVA4 inhibition of specific
CRISPR-Cas12a." Elife, 8.
doi: 10.7554/eLife.49110.
|
cryo-EM structure of lbcas12a-crrna: acrva4 (2:2
complex) . SNAP
output
|
|
6p7p
|
DNA binding protein |
X-ray (1.665 Å) |
Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews
IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos
JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD |
(2020) "Structure
and Mechanism of a Cyclic Trinucleotide-Activated
Bacterial Endonuclease Mediating Bacteriophage
Immunity." Mol.Cell, 77,
723. doi: 10.1016/j.molcel.2019.12.010.
|
Structure of e. coli ms115-1 nucc, caaa-bound form .
SNAP output
|
|
6p7q
|
DNA binding protein |
X-ray (1.66 Å) |
Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews
IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos
JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD |
(2020) "Structure
and Mechanism of a Cyclic Trinucleotide-Activated
Bacterial Endonuclease Mediating Bacteriophage
Immunity." Mol.Cell, 77,
723. doi: 10.1016/j.molcel.2019.12.010.
|
Structure of e. coli ms115-1 nucc, 5'-papa bound form .
SNAP output
|
|
6pc5
|
ribosome |
cryo-EM (2.7 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to compounds 46 and vs1 .
SNAP output
|
|
6pc6
|
ribosome |
cryo-EM (2.5 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to compound 47 . SNAP output
|
|
6pc7
|
ribosome |
cryo-EM (2.5 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to compound 46 . SNAP output
|
|
6pc8
|
ribosome |
cryo-EM (2.9 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to compound 40q . SNAP output
|
|
6pch
|
ribosome |
cryo-EM (2.9 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to compound 21 . SNAP output
|
|
6pcq
|
ribosome |
cryo-EM (2.6 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to vm2 . SNAP output
|
|
6pcr
|
ribosome |
cryo-EM (2.5 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to compound 40o . SNAP output
|
|
6pcs
|
ribosome |
cryo-EM (2.8 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to compound 40e . SNAP output
|
|
6pct
|
ribosome |
cryo-EM (2.8 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to compound 41q . SNAP output
|
|
6pif
|
RNA binding protein-RNA |
cryo-EM (3.4 Å) |
Halpin-Healy TS, Klompe SE, Sternberg SH, Fernandez
IS |
(2020) "Structural
basis of DNA targeting by a transposon-encoded
CRISPR-Cas system." Nature,
577, 271-274. doi: 10.1038/s41586-019-1849-0.
|
V. cholerae tniq-cascade complex, open conformation .
SNAP output
|
|
6pig
|
RNA binding protein-RNA |
cryo-EM (3.5 Å) |
Halpin-Healy TS, Klompe SE, Sternberg SH, Fernandez
IS |
(2020) "Structural
basis of DNA targeting by a transposon-encoded
CRISPR-Cas system." Nature,
577, 271-274. doi: 10.1038/s41586-019-1849-0.
|
V. cholerae tniq-cascade complex, closed conformation .
SNAP output
|
|
6pj6
|
ribosome |
cryo-EM (2.2 Å) |
Stojkovic V, Myasnikov AG, Young ID, Frost A, Fraser
JS, Fujimori DG |
(2020) "Assessment
of the nucleotide modifications in the high-resolution
cryo-electron microscopy structure of the Escherichia
coli 50S subunit." Nucleic Acids Res.,
48, 2723-2732. doi: 10.1093/nar/gkaa037.
|
High resolution cryo-EM structure of e.coli 50s .
SNAP output
|
|
6ppf
|
ribosome |
cryo-EM (3.4 Å) |
Seffouh A, Jain N, Jahagirdar D, Basu K, Razi A, Ni
X, Guarne A, Britton RA, Ortega J |
(2019) "Structural
consequences of the interaction of RbgA with a 50S
ribosomal subunit assembly intermediate."
Nucleic Acids Res., 47,
10414-10425. doi: 10.1093/nar/gkz770.
|
Bacterial 45srbga ribosomal particle class b . SNAP output
|
|
6ppk
|
ribosome |
cryo-EM (4.4 Å) |
Seffouh A, Jain N, Jahagirdar D, Basu K, Razi A, Ni
X, Guarne A, Britton RA, Ortega J |
(2019) "Structural
consequences of the interaction of RbgA with a 50S
ribosomal subunit assembly intermediate."
Nucleic Acids Res., 47,
10414-10425. doi: 10.1093/nar/gkz770.
|
Rbga+45srbga complex . SNAP output
|
|
6ppn
|
RNA binding protein-RNA |
X-ray (1.91 Å) |
Montemayor EJ, Virta JM, Hayes SM, Nomura Y, Brow DA,
Butcher SE |
(2020) "Molecular
basis for the distinct cellular functions of the Lsm1-7
and Lsm2-8 complexes." Rna,
26, 1400-1413. doi: 10.1261/rna.075879.120.
|
Structure of s. pombe lsm2-8 with unprocessed u6 snrna
. SNAP output
|
|
6ppp
|
RNA binding protein-RNA |
X-ray (2.33 Å) |
Montemayor EJ, Virta JM, Hayes SM, Nomura Y, Brow DA,
Butcher SE |
(2020) "Molecular
basis for the distinct cellular functions of the Lsm1-7
and Lsm2-8 complexes." Rna,
26, 1400-1413. doi: 10.1261/rna.075879.120.
|
Structure of s. pombe lsm2-8 with processed u6 snrna .
SNAP output
|
|
6ppq
|
RNA binding protein-RNA |
X-ray (1.81 Å) |
Montemayor EJ, Virta JM, Hayes SM, Nomura Y, Brow DA,
Butcher SE |
(2020) "Molecular
basis for the distinct cellular functions of the Lsm1-7
and Lsm2-8 complexes." Rna,
26, 1400-1413. doi: 10.1261/rna.075879.120.
|
Structure of s. pombe lsm1-7 with RNA, polyuridine with
3' adenosine . SNAP
output
|
|
6ppv
|
RNA binding protein-RNA |
X-ray (2.05 Å) |
Montemayor EJ, Virta JM, Hayes SM, Nomura Y, Brow DA,
Butcher SE |
(2020) "Molecular
basis for the distinct cellular functions of the Lsm1-7
and Lsm2-8 complexes." Rna,
26, 1400-1413. doi: 10.1261/rna.075879.120.
|
Structure of s. pombe lsm1-7 with RNA, polyuridine with
3' guanosine . SNAP
output
|
|
6pun
|
RNA binding protein-RNA |
X-ray (2.099 Å) |
Qiu C, Bhat VD, Rajeev S, Zhang C, Lasley AE, Wine
RN, Campbell ZT, Tanaka Hall TMT |
(2019) "A
crystal structure of a collaborative RNA regulatory
complex reveals mechanisms to refine target
specificity." Elife, 8.
doi: 10.7554/eLife.48968.
|
Crystal structure of a ternary complex of fbf-2 with
lst-1 (site b) and compact fbe RNA . SNAP output
|
|
6pvk
|
ribosome |
cryo-EM (3.4 Å) |
Seffouh A, Jain N, Jahagirdar D, Basu K, Razi A, Ni
X, Guarne A, Britton RA, Ortega J |
(2019) "Structural
consequences of the interaction of RbgA with a 50S
ribosomal subunit assembly intermediate."
Nucleic Acids Res., 47,
10414-10425. doi: 10.1093/nar/gkz770.
|
Bacterial 45srbga ribosomal particle class a . SNAP output
|
|
6pzq
|
metal binding protein-RNA |
X-ray (2.703 Å) |
Gao Y, Cao D, Pawnikar S, John KP, Ahn HM, Hill S, Ha
JM, Parikh P, Ogilvie C, Swain A, Yang A, Bell A, Salazar
A, Miao Y, Liang B |
(2020) "Structure
of the Human Respiratory Syncytial Virus M2-1 Protein
in Complex with a Short Positive-Sense Gene-End
RNA." Structure, 28, 979.
doi: 10.1016/j.str.2020.07.001.
|
Structure of the human respiratory syncytial virus m2-1
protein in complex with a short positive-sense gene-end
RNA . SNAP output
|
|
6q1h
|
DNA binding protein-RNA |
X-ray (1.45 Å) |
Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews
IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos
JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD |
(2020) "Structure
and Mechanism of a Cyclic Trinucleotide-Activated
Bacterial Endonuclease Mediating Bacteriophage
Immunity." Mol.Cell, 77,
723. doi: 10.1016/j.molcel.2019.12.010.
|
Structure of p. aeruginosa atcc27853 nucc, caaa-bound
form . SNAP output
|
|
6q8u
|
RNA |
X-ray (1.99 Å) |
Ashraf S, Huang L, Lilley DMJ |
(2019) "Effect
of methylation of adenine N6on kink turn structure
depends on location." Rna Biol.,
16, 1377-1385. doi: 10.1080/15476286.2019.1630797.
|
Structure of the standard kink turn hmkt-7 variant
a2bm6a bound with afl7ae protein . SNAP output
|
|
6q8y
|
translation |
cryo-EM (3.1 Å) |
Tesina P, Heckel E, Cheng J, Fromont-Racine M,
Buschauer R, Kater L, Beatrix B, Berninghausen O,
Jacquier A, Becker T, Beckmann R |
(2019) "Structure
of the 80S ribosome-Xrn1 nuclease complex."
Nat.Struct.Mol.Biol., 26,
275-280. doi: 10.1038/s41594-019-0202-5.
|
cryo-EM structure of the mrna translating and degrading
yeast 80s ribosome-xrn1 nuclease complex . SNAP output
|
|
6q95
|
ribosome |
cryo-EM (3.7 Å) |
Rae CD, Gordiyenko Y, Ramakrishnan V |
(2019) "How a
circularized tmRNA moves through the ribosome."
Science, 363, 740-744. doi:
10.1126/science.aav9370.
|
Structure of tmrna smpb bound in a site of t.
thermophilus 70s ribosome . SNAP output
|
|
6q97
|
ribosome |
cryo-EM (3.9 Å) |
Rae CD, Gordiyenko Y, Ramakrishnan V |
(2019) "How a
circularized tmRNA moves through the ribosome."
Science, 363, 740-744. doi:
10.1126/science.aav9370.
|
Structure of tmrna smpb bound in a site of e. coli 70s
ribosome . SNAP
output
|
|
6q98
|
ribosome |
cryo-EM (4.3 Å) |
Rae CD, Gordiyenko Y, Ramakrishnan V |
(2019) "How a
circularized tmRNA moves through the ribosome."
Science, 363, 740-744. doi:
10.1126/science.aav9370.
|
Structure of tmrna smpb bound in p site of e. coli 70s
ribosome . SNAP
output
|
|
6q9a
|
ribosome |
cryo-EM (3.7 Å) |
Rae CD, Gordiyenko Y, Ramakrishnan V |
(2019) "How a
circularized tmRNA moves through the ribosome."
Science, 363, 740-744. doi:
10.1126/science.aav9370.
|
Structure of tmrna smpb bound past e site of e. coli
70s ribosome . SNAP
output
|
|
6qcs
|
viral protein |
cryo-EM (3.1 Å) |
Kouba T, Drncova P, Cusack S |
(2019) "Structural
snapshots of actively transcribing influenza
polymerase." Nat.Struct.Mol.Biol.,
26, 460-470. doi: 10.1038/s41594-019-0232-z.
|
Influenza b polymerase pre-initiation complex .
SNAP output
|
|
6qct
|
viral protein |
cryo-EM (3.2 Å) |
Kouba T, Drncova P, Cusack S |
(2019) "Structural
snapshots of actively transcribing influenza
polymerase." Nat.Struct.Mol.Biol.,
26, 460-470. doi: 10.1038/s41594-019-0232-z.
|
Influenza b polymerase elongation complex . SNAP output
|
|
6qcv
|
viral protein |
X-ray (3.24 Å) |
Kouba T, Drncova P, Cusack S |
(2019) "Structural
snapshots of actively transcribing influenza
polymerase." Nat.Struct.Mol.Biol.,
26, 460-470. doi: 10.1038/s41594-019-0232-z.
|
Crystal structure of influenza b polymerase initiation
state with capped 14-mer RNA primer and ctp . SNAP output
|
|
6qcw
|
viral protein |
X-ray (2.88 Å) |
Kouba T, Drncova P, Cusack S |
(2019) "Structural
snapshots of actively transcribing influenza
polymerase." Nat.Struct.Mol.Biol.,
26, 460-470. doi: 10.1038/s41594-019-0232-z.
|
Crystal structure of influenza b polymerase initiation
state with capped 14-mer RNA primer . SNAP output
|
|
6qcx
|
viral protein |
X-ray (3.08 Å) |
Kouba T, Drncova P, Cusack S |
(2019) "Structural
snapshots of actively transcribing influenza
polymerase." Nat.Struct.Mol.Biol.,
26, 460-470. doi: 10.1038/s41594-019-0232-z.
|
Crystal structure of influenza b polymerase initiation
state with capped 15-mer RNA primer . SNAP output
|
|
6qdv
|
splicing |
cryo-EM (3.3 Å) |
Fica SM, Oubridge C, Wilkinson ME, Newman AJ, Nagai
K |
(2019) "A human
postcatalytic spliceosome structure reveals essential
roles of metazoan factors for exon ligation."
Science, 363, 710-714. doi:
10.1126/science.aaw5569.
|
Human post-catalytic p complex spliceosome . SNAP output
|
|
6qdw
|
ribosome |
cryo-EM (2.83 Å) |
Schulte L, Mao J, Reitz J, Sreeramulu S, Kudlinzki D,
Hodirnau VV, Meier-Credo J, Saxena K, Buhr F, Langer JD,
Blackledge M, Frangakis AS, Glaubitz C, Schwalbe H |
(2020) "Cysteine
oxidation and disulfide formation in the ribosomal exit
tunnel." Nat Commun, 11,
5569. doi: 10.1038/s41467-020-19372-x.
|
cryo-EM structure of the 50s ribosomal subunit at 2.83
angstroms with modeled gbc secm peptide . SNAP output
|
|
6qic
|
hydrolase |
X-ray (2.7 Å) |
Hamann F, Enders M, Ficner R |
(2019) "Structural
basis for RNA translocation by DEAH-box ATPases."
Nucleic Acids Res., 47,
4349-4362. doi: 10.1093/nar/gkz150.
|
Crystal structure of deah-box atpase prp22-s837a with
bound ssrna . SNAP
output
|
|
6qik
|
ribosome |
cryo-EM (3.1 Å) |
Kargas V, Castro-Hartmann P, Escudero-Urquijo N, Dent
K, Hilcenko C, Sailer C, Zisser G, Marques-Carvalho MJ,
Pellegrino S, Wawiorka L, Freund SM, Wagstaff JL,
Andreeva A, Faille A, Chen E, Stengel F, Bergler H,
Warren AJ |
(2019) "Mechanism
of completion of peptidyltransferase centre assembly in
eukaryotes." Elife, 8.
doi: 10.7554/eLife.44904.
|
cryo-EM structures of lsg1-tap pre-60s ribosomal
particles . SNAP
output
|
|
6qkl
|
ribosome |
cryo-EM (3.3 Å) |
Weis F, Giudice E, Churcher M, Jin L, Hilcenko C,
Wong CC, Traynor D, Kay RR, Warren AJ |
(2015) "Mechanism
of eIF6 release from the nascent 60S ribosomal
subunit." Nat.Struct.Mol.Biol.,
22, 914-919. doi: 10.1038/nsmb.3112.
|
Mechanism of eif6 release from the nascent 60s
ribosomal subunit . SNAP
output
|
|
6qnq
|
ribosome |
X-ray (3.5 Å) |
Rozov A, Khusainov I, El Omari K, Duman R, Mykhaylyk
V, Yusupov M, Westhof E, Wagner A, Yusupova G |
(2019) "Importance
of potassium ions for ribosome structure and function
revealed by long-wavelength X-ray diffraction."
Nat Commun, 10, 2519. doi:
10.1038/s41467-019-10409-4.
|
70s ribosome initiation complex (ic) with
experimentally assigned potassium ions . SNAP output
|
|
6qnr
|
ribosome |
X-ray (3.1 Å) |
Rozov A, Khusainov I, El Omari K, Duman R, Mykhaylyk
V, Yusupov M, Westhof E, Wagner A, Yusupova G |
(2019) "Importance
of potassium ions for ribosome structure and function
revealed by long-wavelength X-ray diffraction."
Nat Commun, 10, 2519. doi:
10.1038/s41467-019-10409-4.
|
70s ribosome elongation complex (ec) with
experimentally assigned potassium ions . SNAP output
|
|
6qt0
|
ribosome |
cryo-EM (3.4 Å) |
Kargas V, Castro-Hartmann P, Escudero-Urquijo N, Dent
K, Hilcenko C, Sailer C, Zisser G, Marques-Carvalho MJ,
Pellegrino S, Wawiorka L, Freund SM, Wagstaff JL,
Andreeva A, Faille A, Chen E, Stengel F, Bergler H,
Warren AJ |
(2019) "Mechanism
of completion of peptidyltransferase centre assembly in
eukaryotes." Elife, 8.
doi: 10.7554/eLife.44904.
|
cryo-EM structures of lsg1-tap pre-60s ribosomal
particles . SNAP
output
|
|
6qtz
|
ribosome |
cryo-EM (3.5 Å) |
Kargas V, Castro-Hartmann P, Escudero-Urquijo N, Dent
K, Hilcenko C, Sailer C, Zisser G, Marques-Carvalho MJ,
Pellegrino S, Wawiorka L, Freund SM, Wagstaff JL,
Andreeva A, Faille A, Chen E, Stengel F, Bergler H,
Warren AJ |
(2019) "Mechanism
of completion of peptidyltransferase centre assembly in
eukaryotes." Elife, 8.
doi: 10.7554/eLife.44904.
|
cryo-EM structures of lsg1-tap pre-60s ribosomal
particles . SNAP
output
|
|
6qul
|
antibiotic |
cryo-EM (3.0 Å) |
Scaiola A, Leibundgut M, Boehringer D, Caspers P, Bur
D, Locher HH, Rueedi G, Ritz D |
(2019) "Structural
basis of translation inhibition by cadazolid, a novel
quinoxolidinone antibiotic." Sci Rep,
9, 5634. doi: 10.1038/s41598-019-42155-4.
|
Structure of a bacterial 50s ribosomal subunit in
complex with the novel quinoxolidinone antibiotic
cadazolid . SNAP
output
|
|
6qw6
|
splicing |
cryo-EM (2.92 Å) |
Charenton C, Wilkinson ME, Nagai K |
(2019) "Mechanism
of 5' splice site transfer for human spliceosome
activation." Science,
364, 362-367. doi: 10.1126/science.aax3289.
|
Structure of the human u5.u4-u6 tri-snrnp at 2.9a
resolution. . SNAP
output
|
|
6qwl
|
RNA binding protein |
cryo-EM (4.1 Å) |
Fan H, Walker AP, Carrique L, Keown JR, Serna Martin
I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J,
Grimes JM, Fodor E |
(2019) "Structures
of influenza A virus RNA polymerase offer insight into
viral genome replication." Nature,
573, 287-290. doi: 10.1038/s41586-019-1530-7.
|
Influenza b virus (b-panama-45) polymerase
hetermotrimer in complex with 3'5' crna promoter .
SNAP output
|
|
6qx3
|
RNA binding protein |
cryo-EM (3.79 Å) |
Fan H, Walker AP, Carrique L, Keown JR, Serna Martin
I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J,
Grimes JM, Fodor E |
(2019) "Structures
of influenza A virus RNA polymerase offer insight into
viral genome replication." Nature,
573, 287-290. doi: 10.1038/s41586-019-1530-7.
|
Influenza a virus (a-nt-60-1968) polymerase
hetermotrimer in complex with 3'5' crna promoter and
nb8205 . SNAP output
|
|
6qx8
|
RNA binding protein |
cryo-EM (4.07 Å) |
Fan H, Walker AP, Carrique L, Keown JR, Serna Martin
I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J,
Grimes JM, Fodor E |
(2019) "Structures
of influenza A virus RNA polymerase offer insight into
viral genome replication." Nature,
573, 287-290. doi: 10.1038/s41586-019-1530-7.
|
Influenza a virus (a-nt-60-1968) polymerase dimer of
heterotrimer in complex with 5' crna promoter .
SNAP output
|
|
6qx9
|
splicing |
cryo-EM (3.28 Å) |
Charenton C, Wilkinson ME, Nagai K |
(2019) "Mechanism
of 5' splice site transfer for human spliceosome
activation." Science,
364, 362-367. doi: 10.1126/science.aax3289.
|
Structure of a human fully-assembled precatalytic
spliceosome (pre-b complex). . SNAP output
|
|
6qxe
|
RNA binding protein |
cryo-EM (4.15 Å) |
Fan H, Walker AP, Carrique L, Keown JR, Serna Martin
I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J,
Grimes JM, Fodor E |
(2019) "Structures
of influenza A virus RNA polymerase offer insight into
viral genome replication." Nature,
573, 287-290. doi: 10.1038/s41586-019-1530-7.
|
Influenza a virus (a-nt-60-1968) polymerase dimer of
hetermotrimer in complex with 3'5' crna promoter and
nb8205 . SNAP output
|
|
6r5k
|
RNA binding protein |
cryo-EM (4.8 Å) |
Schafer IB, Yamashita M, Schuller JM, Schussler S,
Reichelt P, Strauss M, Conti E |
(2019) "Molecular
Basis for poly(A) RNP Architecture and Recognition by
the Pan2-Pan3 Deadenylase." Cell,
177, 1619. doi: 10.1016/j.cell.2019.04.013.
|
cryo-EM structure of a poly(a) rnp bound to the
pan2-pan3 deadenylase . SNAP output
|
|
6r5q
|
ribosome |
cryo-EM (3.0 Å) |
Shanmuganathan V, Schiller N, Magoulopoulou A, Cheng
J, Braunger K, Cymer F, Berninghausen O, Beatrix B, Kohno
K, Heijne GV, Beckmann R |
(2019) "Structural
and mutational analysis of the ribosome-arresting human
XBP1u." Elife, 8. doi:
10.7554/eLife.46267.
|
Structure of xbp1u-paused ribosome nascent chain
complex (post-state) . SNAP output
|
|
6r6g
|
ribosome |
cryo-EM (3.7 Å) |
Shanmuganathan V, Schiller N, Magoulopoulou A, Cheng
J, Braunger K, Cymer F, Berninghausen O, Beatrix B, Kohno
K, Heijne GV, Beckmann R |
(2019) "Structural
and mutational analysis of the ribosome-arresting human
XBP1u." Elife, 8. doi:
10.7554/eLife.46267.
|
Structure of xbp1u-paused ribosome nascent chain
complex with srp. . SNAP
output
|
|
6r7b
|
RNA binding protein |
X-ray (3.12 Å) |
Molina R, Stella S, Feng M, Sofos N, Jauniskis V,
Pozdnyakova I, Lopez-Mendez B, She Q, Montoya G |
(2019) "Structure
of Csx1-cOA4complex reveals the basis of RNA decay in
Type III-B CRISPR-Cas." Nat Commun,
10, 4302. doi: 10.1038/s41467-019-12244-z.
|
Crystal structure of csx1 in complex with cyclic
oligoadenylate coa4 conformation 1 . SNAP output
|
|
6r7g
|
virus |
cryo-EM (2.2 Å) |
Grinzato A, Kandiah E, Lico C, Betti C, Baschieri S,
Zanotti G |
(2020) "Atomic
structure of potato virus X, the prototype of the
Alphaflexiviridae family." Nat.Chem.Biol.,
16, 564-569. doi: 10.1038/s41589-020-0502-4.
|
Atomic structure of potato virus x, the prototype of
the alphaflexiviridae family . SNAP output
|
|
6r7q
|
ribosome |
cryo-EM (3.9 Å) |
Shanmuganathan V, Schiller N, Magoulopoulou A, Cheng
J, Braunger K, Cymer F, Berninghausen O, Beatrix B, Kohno
K, Heijne GV, Beckmann R |
(2019) "Structural
and mutational analysis of the ribosome-arresting human
XBP1u." Elife, 8. doi:
10.7554/eLife.46267.
|
Structure of xbp1u-paused ribosome nascent chain
complex with sec61. . SNAP output
|
|
6r84
|
ribosome |
cryo-EM (3.6 Å) |
Su T, Izawa T, Thoms M, Yamashita Y, Cheng J,
Berninghausen O, Hartl FU, Inada T, Neupert W, Beckmann
R |
(2019) "Structure
and function of Vms1 and Arb1 in RQC and mitochondrial
proteome homeostasis." Nature,
570, 538-542. doi: 10.1038/s41586-019-1307-z.
|
Yeast vms1 (q295l)-60s ribosomal subunit complex
(pre-state with arb1) . SNAP output
|
|
6r86
|
ribosome |
cryo-EM (3.4 Å) |
Su T, Izawa T, Thoms M, Yamashita Y, Cheng J,
Berninghausen O, Hartl FU, Inada T, Neupert W, Beckmann
R |
(2019) "Structure
and function of Vms1 and Arb1 in RQC and mitochondrial
proteome homeostasis." Nature,
570, 538-542. doi: 10.1038/s41586-019-1307-z.
|
Yeast vms1-60s ribosomal subunit complex (post-state) .
SNAP output
|
|
6r87
|
ribosome |
cryo-EM (3.4 Å) |
Su T, Izawa T, Thoms M, Yamashita Y, Cheng J,
Berninghausen O, Hartl FU, Inada T, Neupert W, Beckmann
R |
(2019) "Structure
and function of Vms1 and Arb1 in RQC and mitochondrial
proteome homeostasis." Nature,
570, 538-542. doi: 10.1038/s41586-019-1307-z.
|
Yeast vms1 (q295l)-60s ribosomal subunit complex
(pre-state without arb1) . SNAP output
|
|
6r9j
|
hydrolase |
X-ray (3.326 Å) |
Tang TTL, Stowell JAW, Hill CH, Passmore LA |
(2019) "The
intrinsic structure of poly(A) RNA determines the
specificity of Pan2 and Caf1 deadenylases."
Nat.Struct.Mol.Biol., 26,
433-442. doi: 10.1038/s41594-019-0227-9.
|
Structure of saccharomyces cerevisiae apo pan2
pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)
module in complex with a7 RNA . SNAP output
|
|
6r9m
|
hydrolase |
X-ray (3.329 Å) |
Tang TTL, Stowell JAW, Hill CH, Passmore LA |
(2019) "The
intrinsic structure of poly(A) RNA determines the
specificity of Pan2 and Caf1 deadenylases."
Nat.Struct.Mol.Biol., 26,
433-442. doi: 10.1038/s41594-019-0227-9.
|
Structure of saccharomyces cerevisiae apo pan2
pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)
module in complex with aaggaa RNA . SNAP output
|
|
6r9o
|
hydrolase |
X-ray (3.319 Å) |
Tang TTL, Stowell JAW, Hill CH, Passmore LA |
(2019) "The
intrinsic structure of poly(A) RNA determines the
specificity of Pan2 and Caf1 deadenylases."
Nat.Struct.Mol.Biol., 26,
433-442. doi: 10.1038/s41594-019-0227-9.
|
Structure of saccharomyces cerevisiae apo pan2
pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)
module in complex with aagga RNA . SNAP output
|
|
6r9p
|
hydrolase |
X-ray (2.98 Å) |
Tang TTL, Stowell JAW, Hill CH, Passmore LA |
(2019) "The
intrinsic structure of poly(A) RNA determines the
specificity of Pan2 and Caf1 deadenylases."
Nat.Struct.Mol.Biol., 26,
433-442. doi: 10.1038/s41594-019-0227-9.
|
Structure of saccharomyces cerevisiae apo pan2
pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)
module in complex with aauuaa RNA . SNAP output
|
|
6r9q
|
hydrolase |
X-ray (3.079 Å) |
Tang TTL, Stowell JAW, Hill CH, Passmore LA |
(2019) "The
intrinsic structure of poly(A) RNA determines the
specificity of Pan2 and Caf1 deadenylases."
Nat.Struct.Mol.Biol., 26,
433-442. doi: 10.1038/s41594-019-0227-9.
|
Structure of saccharomyces cerevisiae apo pan2
pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)
module in complex with aaccaa RNA . SNAP output
|
|
6r9r
|
RNA binding protein |
X-ray (2.7 Å) |
Molina R, Stella S, Feng M, Sofos N, Jauniskis V,
Pozdnyakova I, Lopez-Mendez B, She Q, Montoya G |
(2019) "Structure
of Csx1-cOA4complex reveals the basis of RNA decay in
Type III-B CRISPR-Cas." Nat Commun,
10, 4302. doi: 10.1038/s41467-019-12244-z.
|
Crystal structure of csx1 in complex with cyclic
oligoadenylate coa4 conformation 2 . SNAP output
|
|
6ra4
|
RNA binding protein |
X-ray (1.9 Å) |
Greenidge PA, Blommers MJJ, Priestle JP, Hunziker
J |
(2019) "How to
Computationally Stack the Deck for Hit-to-Lead
Generation: In Silico Molecular Interaction Energy
Profiling for de Novo siRNA Guide Strand Surrogate
Selection." J.Chem.Inf.Model.,
59, 1897-1908. doi: 10.1021/acs.jcim.8b00892.
|
Human argonaute-2 paz domain (214-347) in complex with
cgugacucu . SNAP
output
|
|
6rbd
|
ribosome |
cryo-EM (3.47 Å) |
Mitterer V, Shayan R, Ferreira-Cerca S, Murat G, Enne
T, Rinaldi D, Weigl S, Omanic H, Gleizes PE, Kressler D,
Plisson-Chastang C, Pertschy B |
(2019) "Conformational
proofreading of distant 40S ribosomal subunit
maturation events by a long-range communication
mechanism." Nat Commun,
10, 2754. doi: 10.1038/s41467-019-10678-z.
|
State 1 of yeast tsr1-tap rps20-deltaloop pre-40s
particles . SNAP
output
|
|
6rbe
|
ribosome |
cryo-EM (3.8 Å) |
Mitterer V, Shayan R, Ferreira-Cerca S, Murat G, Enne
T, Rinaldi D, Weigl S, Omanic H, Gleizes PE, Kressler D,
Plisson-Chastang C, Pertschy B |
(2019) "Conformational
proofreading of distant 40S ribosomal subunit
maturation events by a long-range communication
mechanism." Nat Commun,
10, 2754. doi: 10.1038/s41467-019-10678-z.
|
State 2 of yeast tsr1-tap rps20-deltaloop pre-40s
particles . SNAP
output
|
|
6rcl
|
hydrolase |
X-ray (1.97 Å) |
Nicholls TJ, Spahr H, Jiang S, Siira SJ, Koolmeister
C, Sharma S, Kauppila JHK, Jiang M, Kaever V, Rackham O,
Chabes A, Falkenberg M, Filipovska A, Larsson NG,
Gustafsson CM |
(2019) "Dinucleotide
Degradation by REXO2 Maintains Promoter Specificity in
Mammalian Mitochondria." Mol.Cell,
76, 784-796.e6. doi: 10.1016/j.molcel.2019.09.010.
|
Crystal structure of rexo2-d199a-aa . SNAP output
|
|
6rfl
|
viral protein |
cryo-EM (2.76 Å) |
Grimm C, Hillen HS, Bedenk K, Bartuli J, Neyer S,
Zhang Q, Huttenhofer A, Erlacher M, Dienemann C,
Schlosser A, Urlaub H, Bottcher B, Szalay AA, Cramer P,
Fischer U |
(2019) "Structural
Basis of Poxvirus Transcription: Vaccinia RNA
Polymerase Complexes." Cell,
179, 1537-1550.e19. doi: 10.1016/j.cell.2019.11.024.
|
Structure of the complete vaccinia DNA-dependent RNA
polymerase complex . SNAP output
|
|
6ri5
|
ribosome |
cryo-EM (3.3 Å) |
Kargas V, Castro-Hartmann P, Escudero-Urquijo N, Dent
K, Hilcenko C, Sailer C, Zisser G, Marques-Carvalho MJ,
Pellegrino S, Wawiorka L, Freund SM, Wagstaff JL,
Andreeva A, Faille A, Chen E, Stengel F, Bergler H,
Warren AJ |
(2019) "Mechanism
of completion of peptidyltransferase centre assembly in
eukaryotes." Elife, 8.
doi: 10.7554/eLife.44904.
|
cryo-EM structures of lsg1-tap pre-60s ribosomal
particles . SNAP
output
|
|
6rlp
|
viral protein |
cryo-EM (2.3 Å) |
Kandiah E, Giraud T, de Maria Antolinos A, Dobias F,
Effantin G, Flot D, Hons M, Schoehn G, Susini J, Svensson
O, Leonard GA, Mueller-Dieckmann C |
(2019) "CM01: a
facility for cryo-electron microscopy at the European
Synchrotron." Acta Crystallogr D Struct
Biol, 75, 528-535. doi: 10.1107/S2059798319006880.
|
cryo-EM reconstruction of tmv coat protein . SNAP output
|
|
6rm3
|
ribosome |
cryo-EM (3.4 Å) |
Barandun J, Hunziker M, Vossbrinck CR, Klinge S |
(2019) "Evolutionary
compaction and adaptation visualized by the structure
of the dormant microsporidian ribosome." Nat
Microbiol, 4, 1798-1804. doi:
10.1038/s41564-019-0514-6.
|
Evolutionary compaction and adaptation visualized by
the structure of the dormant microsporidian ribosome .
SNAP output
|
|
6rr7
|
RNA binding protein |
cryo-EM (3.01 Å) |
Fan H, Walker AP, Carrique L, Keown JR, Serna Martin
I, Karia D, Sharps J, Hengrung N, Pardon E, Steyaert J,
Grimes JM, Fodor E |
(2019) "Structures
of influenza A virus RNA polymerase offer insight into
viral genome replication." Nature,
573, 287-290. doi: 10.1038/s41586-019-1530-7.
|
Influenza a virus (a-nt-60-1968) polymerase
heterotrimer bound to 3'5' vrna promoter and capped RNA
primer . SNAP output
|
|
6rti
|
hydrolase |
X-ray (2.2 Å) |
Ptacek J, Zhang D, Qiu L, Kruspe S, Motlova L,
Kolenko P, Novakova Z, Shubham S, Havlinova B, Baranova
P, Chen SJ, Zou X, Giangrande P, Barinka C |
(2020) "Structural
basis of prostate-specific membrane antigen recognition
by the A9g RNA aptamer." Nucleic Acids
Res., 48, 11130-11145. doi:
10.1093/nar/gkaa494.
|
X-ray structure of human glutamate carboxypeptidase ii
(gcpii) in complex with aptamer a9g . SNAP output
|
|
6rw4
|
ribosome |
cryo-EM (2.97 Å) |
Khawaja A, Itoh Y, Remes C, Spahr H, Yukhnovets O,
Hofig H, Amunts A, Rorbach J |
(2020) "Distinct
pre-initiation steps in human mitochondrial
translation." Nat Commun,
11, 2932. doi: 10.1038/s41467-020-16503-2.
|
Structure of human mitochondrial 28s ribosome in
complex with mitochondrial if3 . SNAP output
|
|
6rw5
|
ribosome |
cryo-EM (3.14 Å) |
Khawaja A, Itoh Y, Remes C, Spahr H, Yukhnovets O,
Hofig H, Amunts A, Rorbach J |
(2020) "Distinct
pre-initiation steps in human mitochondrial
translation." Nat Commun,
11, 2932. doi: 10.1038/s41467-020-16503-2.
|
Structure of human mitochondrial 28s ribosome in
complex with mitochondrial if2 and if3 . SNAP output
|
|
6rxt
|
ribosome |
cryo-EM (7.0 Å) |
Cheng J, Bassler J, Fischer P, Lau B, Kellner N,
Kunze R, Griesel S, Kallas M, Berninghausen O, Strauss D,
Beckmann R, Hurt E |
(2019) "Thermophile
90S Pre-ribosome Structures Reveal the Reverse Order of
Co-transcriptional 18S rRNA Subdomain Integration."
Mol.Cell, 75, 1256-1269.e7.
doi: 10.1016/j.molcel.2019.06.032.
|
cryo-EM structure of the 90s pre-ribosome (kre33-noc4)
from chaetomium thermophilum, state a . SNAP output
|
|
6rxu
|
ribosome |
cryo-EM (3.5 Å) |
Cheng J, Bassler J, Fischer P, Lau B, Kellner N,
Kunze R, Griesel S, Kallas M, Berninghausen O, Strauss D,
Beckmann R, Hurt E |
(2019) "Thermophile
90S Pre-ribosome Structures Reveal the Reverse Order of
Co-transcriptional 18S rRNA Subdomain Integration."
Mol.Cell, 75, 1256-1269.e7.
doi: 10.1016/j.molcel.2019.06.032.
|
cryo-EM structure of the 90s pre-ribosome (kre33-noc4)
from chaetomium thermophilum, state b1 . SNAP output
|
|
6rxv
|
ribosome |
cryo-EM (4.0 Å) |
Cheng J, Bassler J, Fischer P, Lau B, Kellner N,
Kunze R, Griesel S, Kallas M, Berninghausen O, Strauss D,
Beckmann R, Hurt E |
(2019) "Thermophile
90S Pre-ribosome Structures Reveal the Reverse Order of
Co-transcriptional 18S rRNA Subdomain Integration."
Mol.Cell, 75, 1256-1269.e7.
doi: 10.1016/j.molcel.2019.06.032.
|
cryo-EM structure of the 90s pre-ribosome (kre33-noc4)
from chaetomium thermophilum, state b2 . SNAP output
|
|
6rxx
|
ribosome |
cryo-EM (7.1 Å) |
Cheng J, Bassler J, Fischer P, Lau B, Kellner N,
Kunze R, Griesel S, Kallas M, Berninghausen O, Strauss D,
Beckmann R, Hurt E |
(2019) "Thermophile
90S Pre-ribosome Structures Reveal the Reverse Order of
Co-transcriptional 18S rRNA Subdomain Integration."
Mol.Cell, 75, 1256-1269.e7.
doi: 10.1016/j.molcel.2019.06.032.
|
cryo-EM structure of the 90s pre-ribosome (kre33-noc4)
from chaetomium thermophilum, state c, poly-ala .
SNAP output
|
|
6rxy
|
ribosome |
cryo-EM (4.7 Å) |
Cheng J, Bassler J, Fischer P, Lau B, Kellner N,
Kunze R, Griesel S, Kallas M, Berninghausen O, Strauss D,
Beckmann R, Hurt E |
(2019) "Thermophile
90S Pre-ribosome Structures Reveal the Reverse Order of
Co-transcriptional 18S rRNA Subdomain Integration."
Mol.Cell, 75, 1256-1269.e7.
doi: 10.1016/j.molcel.2019.06.032.
|
cryo-EM structure of the 90s pre-ribosome (kre33-noc4)
from chaetomium thermophilum, state a . SNAP output
|
|
6rxz
|
ribosome |
cryo-EM (4.4 Å) |
Cheng J, Bassler J, Fischer P, Lau B, Kellner N,
Kunze R, Griesel S, Kallas M, Berninghausen O, Strauss D,
Beckmann R, Hurt E |
(2019) "Thermophile
90S Pre-ribosome Structures Reveal the Reverse Order of
Co-transcriptional 18S rRNA Subdomain Integration."
Mol.Cell, 75, 1256-1269.e7.
doi: 10.1016/j.molcel.2019.06.032.
|
cryo-EM structure of the 90s pre-ribosome (kre33-noc4)
from chaetomium thermophilum, state b . SNAP output
|
|
6rzz
|
ribosome |
cryo-EM (3.2 Å) |
Kargas V, Castro-Hartmann P, Escudero-Urquijo N, Dent
K, Hilcenko C, Sailer C, Zisser G, Marques-Carvalho MJ,
Pellegrino S, Wawiorka L, Freund SM, Wagstaff JL,
Andreeva A, Faille A, Chen E, Stengel F, Bergler H,
Warren AJ |
(2019) "Mechanism
of completion of peptidyltransferase centre assembly in
eukaryotes." Elife, 8.
doi: 10.7554/eLife.44904.
|
cryo-EM structures of lsg1-tap pre-60s ribosomal
particles . SNAP
output
|
|
6s05
|
ribosome |
cryo-EM (3.9 Å) |
Kargas V, Castro-Hartmann P, Escudero-Urquijo N, Dent
K, Hilcenko C, Sailer C, Zisser G, Marques-Carvalho MJ,
Pellegrino S, Wawiorka L, Freund SM, Wagstaff JL,
Andreeva A, Faille A, Chen E, Stengel F, Bergler H,
Warren AJ |
(2019) "Mechanism
of completion of peptidyltransferase centre assembly in
eukaryotes." Elife, 8.
doi: 10.7554/eLife.44904.
|
cryo-EM structures of lsg1-tap pre-60s ribosomal
particles . SNAP
output
|
|
6s0k
|
ribosome |
cryo-EM (3.1 Å) |
Wang S, Jomaa A, Jaskolowski M, Yang CI, Ban N, Shan
SO |
(2019) "The
molecular mechanism of cotranslational membrane protein
recognition and targeting by SecA."
Nat.Struct.Mol.Biol., 26,
919-929. doi: 10.1038/s41594-019-0297-8.
|
Ribosome nascent chain in complex with seca . SNAP output
|
|
6s0m
|
RNA binding protein |
X-ray (2.0 Å) |
Calvanese L, Squeglia F, Romano M, D'Auria G,
Falcigno L, Berisio R |
(2020) "Structural
and dynamic studies provide insights into specificity
and allosteric regulation of ribonuclease as, a key
enzyme in mycobacterial virulence."
J.Biomol.Struct.Dyn., 38,
2455-2467. doi: 10.1080/07391102.2019.1643786.
|
Structural and dynamic studies provide insights into
specificity and allosteric regulation of ribonuclease
as, a key enzyme in mycobacterial virulence . SNAP output
|
|
6s0x
|
ribosome |
cryo-EM (2.425 Å) |
Halfon Y, Matzov D, Eyal Z, Bashan A, Zimmerman E,
Kjeldgaard J, Ingmer H, Yonath A |
(2019) "Exit
tunnel modulation as resistance mechanism of S. aureus
erythromycin resistant mutant." Sci Rep,
9, 11460. doi: 10.1038/s41598-019-48019-1.
|
Erythromycin resistant staphylococcus aureus 70s
ribosome (delta r88 a89 ul22) in complex with
erythromycin. . SNAP
output
|
|
6s0z
|
ribosome |
cryo-EM (2.3 Å) |
Halfon Y, Matzov D, Eyal Z, Bashan A, Zimmerman E,
Kjeldgaard J, Ingmer H, Yonath A |
(2019) "Exit
tunnel modulation as resistance mechanism of S. aureus
erythromycin resistant mutant." Sci Rep,
9, 11460. doi: 10.1038/s41598-019-48019-1.
|
Erythromycin resistant staphylococcus aureus 50s
ribosome (delta r88 a89 ul22) in complex with
erythromycin. . SNAP
output
|
|
6s12
|
ribosome |
cryo-EM (3.2 Å) |
Halfon Y, Matzov D, Eyal Z, Bashan A, Zimmerman E,
Kjeldgaard J, Ingmer H, Yonath A |
(2019) "Exit
tunnel modulation as resistance mechanism of S. aureus
erythromycin resistant mutant." Sci Rep,
9, 11460. doi: 10.1038/s41598-019-48019-1.
|
Erythromycin resistant staphylococcus aureus 50s
ribosome (delta r88 a89 ul22). . SNAP output
|
|
6s13
|
ribosome |
cryo-EM (3.58 Å) |
Halfon Y, Matzov D, Eyal Z, Bashan A, Zimmerman E,
Kjeldgaard J, Ingmer H, Yonath A |
(2019) "Exit
tunnel modulation as resistance mechanism of S. aureus
erythromycin resistant mutant." Sci Rep,
9, 11460. doi: 10.1038/s41598-019-48019-1.
|
Erythromycin resistant staphylococcus aureus 70s
ribosome (delta r88 a89 ul22). . SNAP output
|
|
6s47
|
ribosomal protein |
cryo-EM (3.28 Å) |
Kasari V, Pochopien AA, Margus T, Murina V, Turnbull
K, Zhou Y, Nissan T, Graf M, Novacek J, Atkinson GC,
Johansson MJO, Wilson DN, Hauryliuk V |
(2019) "A role
for the Saccharomyces cerevisiae ABCF protein New1 in
translation termination/recycling." Nucleic
Acids Res., 47, 8807-8820. doi:
10.1093/nar/gkz600.
|
Saccharomyces cerevisiae 80s ribosome bound with abcf
protein new1 . SNAP
output
|
|
6s6b
|
antiviral protein |
cryo-EM (2.75 Å) |
Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J,
Huang Q, Li Y, She Q, Montoya G |
(2020) "Structures
of the Cmr-beta Complex Reveal the Regulation of the
Immunity Mechanism of Type III-B CRISPR-Cas."
Mol.Cell, 79, 741-757.e7.
doi: 10.1016/j.molcel.2020.07.008.
|
Type iii-b cmr-beta cryo-EM structure of the apo state
. SNAP output
|
|
6s8b
|
antiviral protein |
cryo-EM (2.41 Å) |
Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J,
Huang Q, Li Y, She Q, Montoya G |
(2020) "Structures
of the Cmr-beta Complex Reveal the Regulation of the
Immunity Mechanism of Type III-B CRISPR-Cas."
Mol.Cell, 79, 741-757.e7.
doi: 10.1016/j.molcel.2020.07.008.
|
cryo-EM structure of the type iii-b cmr-beta bound to
cognate target RNA and amppnp, state 1 . SNAP output
|
|
6s8e
|
antiviral protein |
cryo-EM (3.1 Å) |
Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J,
Huang Q, Li Y, She Q, Montoya G |
(2020) "Structures
of the Cmr-beta Complex Reveal the Regulation of the
Immunity Mechanism of Type III-B CRISPR-Cas."
Mol.Cell, 79, 741-757.e7.
doi: 10.1016/j.molcel.2020.07.008.
|
cryo-EM structure of the type iii-b cmr-beta complex
bound to non-cognate target RNA . SNAP output
|
|
6s91
|
antiviral protein |
cryo-EM (2.68 Å) |
Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J,
Huang Q, Li Y, She Q, Montoya G |
(2020) "Structures
of the Cmr-beta Complex Reveal the Regulation of the
Immunity Mechanism of Type III-B CRISPR-Cas."
Mol.Cell, 79, 741-757.e7.
doi: 10.1016/j.molcel.2020.07.008.
|
cryo-EM structure of the type iii-b cmr-beta bound to
cognate target RNA and amppnp, state 2 . SNAP output
|
|
6sae
|
virus |
cryo-EM (1.9 Å) |
Weis F, Beckers M, von der Hocht I, Sachse C |
(2019) "Elucidation
of the viral disassembly switch of tobacco mosaic
virus." Embo Rep., 20,
e48451. doi: 10.15252/embr.201948451.
|
cryo-EM structure of tmv in water . SNAP output
|
|
6sag
|
virus |
cryo-EM (2.0 Å) |
Weis F, Beckers M, von der Hocht I, Sachse C |
(2019) "Elucidation
of the viral disassembly switch of tobacco mosaic
virus." Embo Rep., 20,
e48451. doi: 10.15252/embr.201948451.
|
cryo-EM structure of tmv with ca2+ at low ph . SNAP output
|
|
6sce
|
DNA |
X-ray (1.83 Å) |
McMahon SA, Zhu W, Graham S, Rambo R, White MF,
Gloster TM |
(2020) "Structure
and mechanism of a Type III CRISPR defence DNA nuclease
activated by cyclic oligoadenylate." Nat
Commun, 11, 500. doi: 10.1038/s41467-019-14222-x.
|
Structure of a type iii crispr defence DNA nuclease
activated by cyclic oligoadenylate . SNAP output
|
|
6scf
|
DNA |
X-ray (1.55 Å) |
Athukoralage JS, McMahon SA, Zhang C, Gruschow S,
Graham S, Krupovic M, Whitaker RJ, Gloster TM, White
MF |
(2020) "An
anti-CRISPR viral ring nuclease subverts type III
CRISPR immunity." Nature,
577, 572-575. doi: 10.1038/s41586-019-1909-5.
|
A viral anti-crispr subverts type iii crispr immunity
by rapid degradation of cyclic oligoadenylate .
SNAP output
|
|
6sdw
|
RNA binding protein |
NMR |
Yadav DK, Zigackova D, Zlobina M, Klumpler T,
Beaumont C, Kubickova M, Vanacova S, Lukavsky PJ |
(2020) "Staufen1
reads out structure and sequence features in ARF1 dsRNA
for target recognition." Nucleic Acids
Res., 48, 2091-2106. doi:
10.1093/nar/gkz1163.
|
Solution structure of staufen1 dsrbd3+4 - harf1 sbs
dsrna complex. . SNAP
output
|
|
6sdy
|
RNA binding protein |
NMR |
Yadav DK, Zigackova D, Zlobina M, Klumpler T,
Beaumont C, Kubickova M, Vanacova S, Lukavsky PJ |
(2020) "Staufen1
reads out structure and sequence features in ARF1 dsRNA
for target recognition." Nucleic Acids
Res., 48, 2091-2106. doi:
10.1093/nar/gkz1163.
|
Solution structure of staufen1 dsrbd4 - harf1 sbs dsrna
complex. . SNAP
output
|
|
6sg9
|
ribosome |
cryo-EM (3.1 Å) |
Saurer M, Ramrath DJF, Niemann M, Calderaro S, Prange
C, Mattei S, Scaiola A, Leitner A, Bieri P, Horn EK,
Leibundgut M, Boehringer D, Schneider A, Ban N |
(2019) "Mitoribosomal
small subunit biogenesis in trypanosomes involves an
extensive assembly machinery." Science,
365, 1144-1149. doi: 10.1126/science.aaw5570.
|
Head domain of the mt-ssu assemblosome from trypanosoma
brucei . SNAP output
|
|
6sga
|
ribosome |
cryo-EM (3.1 Å) |
Saurer M, Ramrath DJF, Niemann M, Calderaro S, Prange
C, Mattei S, Scaiola A, Leitner A, Bieri P, Horn EK,
Leibundgut M, Boehringer D, Schneider A, Ban N |
(2019) "Mitoribosomal
small subunit biogenesis in trypanosomes involves an
extensive assembly machinery." Science,
365, 1144-1149. doi: 10.1126/science.aaw5570.
|
Body domain of the mt-ssu assemblosome from trypanosoma
brucei . SNAP output
|
|
6sgb
|
ribosome |
cryo-EM (3.3 Å) |
Saurer M, Ramrath DJF, Niemann M, Calderaro S, Prange
C, Mattei S, Scaiola A, Leitner A, Bieri P, Horn EK,
Leibundgut M, Boehringer D, Schneider A, Ban N |
(2019) "Mitoribosomal
small subunit biogenesis in trypanosomes involves an
extensive assembly machinery." Science,
365, 1144-1149. doi: 10.1126/science.aaw5570.
|
Mt-ssu assemblosome of trypanosoma brucei . SNAP output
|
|
6sgc
|
ribosome |
cryo-EM (2.8 Å) |
Chandrasekaran V, Juszkiewicz S, Choi J, Puglisi JD,
Brown A, Shao S, Ramakrishnan V, Hegde RS |
(2019) "Mechanism
of ribosome stalling during translation of a poly(A)
tail." Nat.Struct.Mol.Biol.,
26, 1132-1140. doi: 10.1038/s41594-019-0331-x.
|
Rabbit 80s ribosome stalled on a poly(a) tail .
SNAP output
|
|
6sh8
|
antiviral protein |
cryo-EM (3.14 Å) |
Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J,
Huang Q, Li Y, She Q, Montoya G |
(2020) "Structures
of the Cmr-beta Complex Reveal the Regulation of the
Immunity Mechanism of Type III-B CRISPR-Cas."
Mol.Cell, 79, 741-757.e7.
doi: 10.1016/j.molcel.2020.07.008.
|
cryo-EM structure of the type iii-b cmr-beta bound to
cognate target RNA and amppnp, state 2, in the presence
of ssDNA . SNAP
output
|
|
6shb
|
antiviral protein |
cryo-EM (3.07 Å) |
Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J,
Huang Q, Li Y, She Q, Montoya G |
(2020) "Structures
of the Cmr-beta Complex Reveal the Regulation of the
Immunity Mechanism of Type III-B CRISPR-Cas."
Mol.Cell, 79, 741-757.e7.
doi: 10.1016/j.molcel.2020.07.008.
|
cryo-EM structure of the type iii-b cmr-beta bound to
cognate target RNA and amppnp, state 1, in the presence
of ssDNA . SNAP
output
|
|
6sic
|
antiviral protein |
cryo-EM (3.52 Å) |
Sofos N, Feng M, Stella S, Pape T, Fuglsang A, Lin J,
Huang Q, Li Y, She Q, Montoya G |
(2020) "Structures
of the Cmr-beta Complex Reveal the Regulation of the
Immunity Mechanism of Type III-B CRISPR-Cas."
Mol.Cell, 79, 741-757.e7.
doi: 10.1016/j.molcel.2020.07.008.
|
cryo-EM structure of the type iii-b cmr-beta bound to
cognate target RNA . SNAP output
|
|
6sj6
|
ribosome |
cryo-EM (3.23 Å) |
Khusainov I, Fatkhullin B, Pellegrino S, Bikmullin A,
Liu WT, Gabdulkhakov A, Shebel AA, Golubev A, Zeyer D,
Trachtmann N, Sprenger GA, Validov S, Usachev K, Yusupova
G, Yusupov M |
(2020) "Mechanism
of ribosome shutdown by RsfS in Staphylococcus aureus
revealed by integrative structural biology
approach." Nat Commun,
11, 1656. doi: 10.1038/s41467-020-15517-0.
|
cryo-EM structure of 50s-rsfs complex from
staphylococcus aureus . SNAP output
|
|
6sjd
|
RNA binding protein |
X-ray (3.29 Å) |
Jolma A, Zhang J, Mondragon E, Morgunova E, Kivioja
T, Laverty KU, Yin Y, Zhu F, Bourenkov G, Morris Q,
Hughes TR, Maher 3rd LJ, Taipale J |
(2020) "Binding
specificities of human RNA-binding proteins toward
structured and linear RNA sequences." Genome
Res., 30, 962-973. doi: 10.1101/gr.258848.119.
|
Zc3h12b-ribonuclease domain bound to RNA . SNAP output
|
|
6skf
|
ribosome |
cryo-EM (2.95 Å) |
Sas-Chen A, Thomas JM, Matzov D, Taoka M, Nance KD,
Nir R, Bryson KM, Shachar R, Liman GLS, Burkhart BW,
Gamage ST, Nobe Y, Briney CA, Levy MJ, Fuchs RT, Robb GB,
Hartmann J, Sharma S, Lin Q, Florens L, Washburn MP,
Isobe T, Santangelo TJ, Shalev-Benami M, Meier JL,
Schwartz S |
(2020) "Dynamic
RNA acetylation revealed by quantitative
cross-evolutionary mapping." Nature,
583, 638-643. doi: 10.1038/s41586-020-2418-2.
|
cryo-EM structure of t. kodakarensis 70s ribosome .
SNAP output
|
|
6skg
|
ribosome |
cryo-EM (2.65 Å) |
Sas-Chen A, Thomas JM, Matzov D, Taoka M, Nance KD,
Nir R, Bryson KM, Shachar R, Liman GLS, Burkhart BW,
Gamage ST, Nobe Y, Briney CA, Levy MJ, Fuchs RT, Robb GB,
Hartmann J, Sharma S, Lin Q, Florens L, Washburn MP,
Isobe T, Santangelo TJ, Shalev-Benami M, Meier JL,
Schwartz S |
(2020) "Dynamic
RNA acetylation revealed by quantitative
cross-evolutionary mapping." Nature,
583, 638-643. doi: 10.1038/s41586-020-2418-2.
|
cryo-EM structure of t. kodakarensis 70s ribosome in
tknat10 deleted strain . SNAP output
|
|
6snj
|
splicing |
NMR |
Jutzi D, Campagne S, Schmidt R, Reber S,
Mechtersheimer J, Gypas F, Schweingruber C, Colombo M,
von Schroetter C, Loughlin FE, Devoy A, Hedlund E,
Zavolan M, Allain FH, Ruepp MD |
(2020) "Aberrant
interaction of FUS with the U1 snRNA provides a
molecular mechanism of FUS induced amyotrophic lateral
sclerosis." Nat Commun,
11, 6341. doi: 10.1038/s41467-020-20191-3.
|
Solution structure of the fus-tls RNA recognition motif
in complex with u1 snrna stem loop iii . SNAP output
|
|
6snt
|
translation |
cryo-EM (2.8 Å) |
Matsuo Y, Tesina P, Nakajima S, Mizuno M, Endo A,
Buschauer R, Cheng J, Shounai O, Ikeuchi K, Saeki Y,
Becker T, Beckmann R, Inada T |
(2020) "RQT
complex dissociates ribosomes collided on endogenous
RQC substrate SDD1." Nat.Struct.Mol.Biol.,
27, 323-332. doi: 10.1038/s41594-020-0393-9.
|
Yeast 80s ribosome stalled on sdd1 mrna. . SNAP output
|
|
6so9
|
RNA binding protein |
NMR |
Upadhyay SK, Mackereth CD |
(2020) "Structural
basis of UCUU RNA motif recognition by splicing factor
RBM20." Nucleic Acids Res.,
48, 4538-4550. doi: 10.1093/nar/gkaa168.
|
Mouse rbm20 rrm domain in complex with aucuua RNA .
SNAP output
|
|
6spb
|
ribosome |
cryo-EM (2.82 Å) |
Halfon Y, Jimenez-Fernandez A, La Rosa R, Espinosa
Portero R, Krogh Johansen H, Matzov D, Eyal Z, Bashan A,
Zimmerman E, Belousoff M, Molin S, Yonath A |
(2019) "Structure
ofPseudomonas aeruginosaribosomes from an
aminoglycoside-resistant clinical isolate."
Proc.Natl.Acad.Sci.USA, 116,
22275-22281. doi: 10.1073/pnas.1909831116.
|
Pseudomonas aeruginosa 50s ribosome from a clinical
isolate with a mutation in ul6 . SNAP output
|
|
6spc
|
ribosome |
cryo-EM (2.95 Å) |
Halfon Y, Jimenez-Fernandez A, La Rosa R, Espinosa
Portero R, Krogh Johansen H, Matzov D, Eyal Z, Bashan A,
Zimmerman E, Belousoff M, Molin S, Yonath A |
(2019) "Structure
ofPseudomonas aeruginosaribosomes from an
aminoglycoside-resistant clinical isolate."
Proc.Natl.Acad.Sci.USA, 116,
22275-22281. doi: 10.1073/pnas.1909831116.
|
Pseudomonas aeruginosa 30s ribosome from an
aminoglycoside resistant clinical isolate . SNAP output
|
|
6spd
|
ribosome |
cryo-EM (3.28 Å) |
Halfon Y, Jimenez-Fernandez A, La Rosa R, Espinosa
Portero R, Krogh Johansen H, Matzov D, Eyal Z, Bashan A,
Zimmerman E, Belousoff M, Molin S, Yonath A |
(2019) "Structure
ofPseudomonas aeruginosaribosomes from an
aminoglycoside-resistant clinical isolate."
Proc.Natl.Acad.Sci.USA, 116,
22275-22281. doi: 10.1073/pnas.1909831116.
|
Pseudomonas aeruginosa 50s ribosome from a clinical
isolate . SNAP
output
|
|
6spe
|
ribosome |
cryo-EM (3.6 Å) |
Halfon Y, Jimenez-Fernandez A, La Rosa R, Espinosa
Portero R, Krogh Johansen H, Matzov D, Eyal Z, Bashan A,
Zimmerman E, Belousoff M, Molin S, Yonath A |
(2019) "Structure
ofPseudomonas aeruginosaribosomes from an
aminoglycoside-resistant clinical isolate."
Proc.Natl.Acad.Sci.USA, 116,
22275-22281. doi: 10.1073/pnas.1909831116.
|
Pseudomonas aeruginosa 30s ribosome from a clinical
isolate . SNAP
output
|
|
6spf
|
ribosome |
cryo-EM (2.89 Å) |
Halfon Y, Jimenez-Fernandez A, La Rosa R, Espinosa
Portero R, Krogh Johansen H, Matzov D, Eyal Z, Bashan A,
Zimmerman E, Belousoff M, Molin S, Yonath A |
(2019) "Structure
ofPseudomonas aeruginosaribosomes from an
aminoglycoside-resistant clinical isolate."
Proc.Natl.Acad.Sci.USA, 116,
22275-22281. doi: 10.1073/pnas.1909831116.
|
Pseudomonas aeruginosa 70s ribosome from an
aminoglycoside resistant clinical isolate . SNAP output
|
|
6spg
|
ribosome |
cryo-EM (3.34 Å) |
Halfon Y, Jimenez-Fernandez A, La Rosa R, Espinosa
Portero R, Krogh Johansen H, Matzov D, Eyal Z, Bashan A,
Zimmerman E, Belousoff M, Molin S, Yonath A |
(2019) "Structure
ofPseudomonas aeruginosaribosomes from an
aminoglycoside-resistant clinical isolate."
Proc.Natl.Acad.Sci.USA, 116,
22275-22281. doi: 10.1073/pnas.1909831116.
|
Pseudomonas aeruginosa 70s ribosome from a clinical
isolate . SNAP
output
|
|
6sqn
|
RNA binding protein |
X-ray (2.05 Å) |
Rosenbach H, Victor J, Borggrafe J, Biehl R, Steger
G, Etzkorn M, Span I |
(2020) "Expanding
crystallization tools for nucleic acid complexes using
U1A protein variants." J.Struct.Biol.,
210, 107480. doi: 10.1016/j.jsb.2020.107480.
|
Structure of the u1a variant a1-98 y31h-q36r-f56w
triple mutant co-crystallized with RNA . SNAP output
|
|
6sqq
|
RNA binding protein |
X-ray (2.37 Å) |
Rosenbach H, Victor J, Borggrafe J, Biehl R, Steger
G, Etzkorn M, Span I |
(2020) "Expanding
crystallization tools for nucleic acid complexes using
U1A protein variants." J.Struct.Biol.,
210, 107480. doi: 10.1016/j.jsb.2020.107480.
|
Structure of the u1a variant a1-98 y31h-q36r-f56w
triple mutant in complex with RNA obtained by soaking .
SNAP output
|
|
6sty
|
RNA binding protein |
X-ray (3.15 Å) |
Szewczyk M, Malik D, Borowski LS, Czarnomska SD,
Kotrys AV, Klosowska-Kosicka K, Nowotny M, Szczesny
RJ |
(2020) "Human
REXO2 controls short mitochondrial RNAs generated by
mtRNA processing and decay machinery to prevent
accumulation of double-stranded RNA." Nucleic
Acids Res., 48, 5572-5590. doi:
10.1093/nar/gkaa302.
|
Human rexo2 exonuclease in complex with RNA. . SNAP output
|
|
6sv4
|
translation |
cryo-EM (3.3 Å) |
Matsuo Y, Tesina P, Nakajima S, Mizuno M, Endo A,
Buschauer R, Cheng J, Shounai O, Ikeuchi K, Saeki Y,
Becker T, Beckmann R, Inada T |
(2020) "RQT
complex dissociates ribosomes collided on endogenous
RQC substrate SDD1." Nat.Struct.Mol.Biol.,
27, 323-332. doi: 10.1038/s41594-020-0393-9.
|
The cryo-EM structure of sdd1-stalled collided trisome.
. SNAP output
|
|
6sw9
|
ribosome |
cryo-EM (4.2 Å) |
Coureux PD, Lazennec-Schurdevin C, Bourcier S,
Mechulam Y, Schmitt E |
(2020) "Cryo-EM
study of an archaeal 30S initiation complex gives
insights into evolution of translation initiation."
Commun Biol, 3, 58. doi:
10.1038/s42003-020-0780-0.
|
Ic2a model of cryo-EM structure of a full archaeal
ribosomal translation initiation complex devoid of aif1
in p. abyssi . SNAP
output
|
|
6swa
|
ribosome |
cryo-EM (3.1 Å) |
Kraushar ML, Krupp F, Harnett D, Turko P,
Ambrozkiewicz MC, Sprink T, Imami K, Gunnigmann M,
Zinnall U, Vieira-Vieira CH, Schaub T, Munster-Wandowski
A, Burger J, Borisova E, Yamamoto H, Rasin MR, Ohler U,
Beule D, Mielke T, Tarabykin V, Landthaler M, Kramer G,
Vida I, Selbach M, Spahn CMT |
(2021) "Protein
Synthesis in the Developing Neocortex at Near-Atomic
Resolution Reveals Ebp1-Mediated Neuronal Proteostasis
at the 60S Tunnel Exit." Mol.Cell,
81, 304. doi: 10.1016/j.molcel.2020.11.037.
|
Mus musculus brain neocortex ribosome 60s bound to ebp1
. SNAP output
|
|
6swc
|
ribosome |
cryo-EM (3.3 Å) |
Coureux PD, Lazennec-Schurdevin C, Bourcier S,
Mechulam Y, Schmitt E |
(2020) "Cryo-EM
study of an archaeal 30S initiation complex gives
insights into evolution of translation initiation."
Commun Biol, 3, 58. doi:
10.1038/s42003-020-0780-0.
|
Ic2b model of cryo-EM structure of a full archaeal
ribosomal translation initiation complex devoid of aif1
in p. abyssi . SNAP
output
|
|
6swd
|
ribosome |
cryo-EM (3.2 Å) |
Coureux PD, Lazennec-Schurdevin C, Bourcier S,
Mechulam Y, Schmitt E |
(2020) "Cryo-EM
study of an archaeal 30S initiation complex gives
insights into evolution of translation initiation."
Commun Biol, 3, 58. doi:
10.1038/s42003-020-0780-0.
|
Ic2 body model of cryo-EM structure of a full archaeal
ribosomal translation initiation complex devoid of aif1
in p. abyssi . SNAP
output
|
|
6swe
|
ribosome |
cryo-EM (3.1 Å) |
Coureux PD, Lazennec-Schurdevin C, Bourcier S,
Mechulam Y, Schmitt E |
(2020) "Cryo-EM
study of an archaeal 30S initiation complex gives
insights into evolution of translation initiation."
Commun Biol, 3, 58. doi:
10.1038/s42003-020-0780-0.
|
Ic2 head of cryo-EM structure of a full archaeal
ribosomal translation initiation complex devoid of aif1
in p. abyssi . SNAP
output
|
|
6sx0
|
viral protein |
X-ray (1.75 Å) |
Wacquiez A, Coste F, Kut E, Gaudon V, Trapp S,
Castaing B, Marc D |
(2020) "Structure
and Sequence Determinants Governing the Interactions of
RNAs with Influenza A Virus Non-Structural Protein
NS1." Viruses, 12. doi:
10.3390/v12090947.
|
Specific dsrna recognition by wild type h7n1 ns1
RNA-binding domain . SNAP output
|
|
6sx2
|
viral protein |
X-ray (1.9 Å) |
Wacquiez A, Coste F, Kut E, Gaudon V, Trapp S,
Castaing B, Marc D |
(2020) "Structure
and Sequence Determinants Governing the Interactions of
RNAs with Influenza A Virus Non-Structural Protein
NS1." Viruses, 12. doi:
10.3390/v12090947.
|
Dsrna recognition by r38ak41a mutant of h7n1 ns1 RNA
binding domain . SNAP
output
|
|
6sxo
|
ribosome |
cryo-EM (3.3 Å) |
Wild K, Aleksic M, Lapouge K, Juaire KD, Flemming D,
Pfeffer S, Sinning I |
(2020) "MetAP-like
Ebp1 occupies the human ribosomal tunnel exit and
recruits flexible rRNA expansion segments." Nat
Commun, 11, 776. doi: 10.1038/s41467-020-14603-7.
|
cryo-EM structure of the human ebp1-ribosome complex .
SNAP output
|
|
6sy4
|
DNA binding protein |
X-ray (2.695 Å) |
Grau FC, Jaeger J, Groher F, Suess B, Muller YA |
(2020) "The
complex formed between a synthetic RNA aptamer and the
transcription repressor TetR is a structural and
functional twin of the operator DNA-TetR regulator
complex." Nucleic Acids Res.,
48, 3366-3378. doi: 10.1093/nar/gkaa083.
|
Tetr in complex with the tetr-binding RNA-aptamer k1 .
SNAP output
|
|
6sy6
|
DNA binding protein |
X-ray (2.9 Å) |
Grau FC, Jaeger J, Groher F, Suess B, Muller YA |
(2020) "The
complex formed between a synthetic RNA aptamer and the
transcription repressor TetR is a structural and
functional twin of the operator DNA-TetR regulator
complex." Nucleic Acids Res.,
48, 3366-3378. doi: 10.1093/nar/gkaa083.
|
Tetr in complex with the tetr-binding RNA-aptamer k2 .
SNAP output
|
|
6szs
|
ribosome |
cryo-EM (3.06 Å) |
Shimokawa-Chiba N, Muller C, Fujiwara K, Beckert B,
Ito K, Wilson DN, Chiba S |
(2019) "Release
factor-dependent ribosome rescue by BrfA in the
Gram-positive bacterium Bacillus subtilis." Nat
Commun, 10, 5397. doi: 10.1038/s41467-019-13408-7.
|
Release factor-dependent ribosome rescue by brfa in the
gram-positive bacterium bacillus subtilis . SNAP output
|
|
6szu
|
viral protein |
cryo-EM (2.41 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell,
181, 877. doi: 10.1016/j.cell.2020.03.061.
|
Bat influenza a polymerase pre-termination complex with
pyrophosphate using 44-mer vrna template with mutated
oligo(u) sequence . SNAP
output
|
|
6szv
|
viral protein |
cryo-EM (2.5 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell,
181, 877. doi: 10.1016/j.cell.2020.03.061.
|
Bat influenza a polymerase elongation complex with
incoming utp analogue (core + endonuclease only) .
SNAP output
|
|
6t0n
|
viral protein |
cryo-EM (2.54 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell,
181, 877. doi: 10.1016/j.cell.2020.03.061.
|
Bat influenza a polymerase pre-initiation complex .
SNAP output
|
|
6t0r
|
viral protein |
cryo-EM (2.82 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell,
181, 877. doi: 10.1016/j.cell.2020.03.061.
|
Bat influenza a polymerase product dissociation complex
using 44-mer vrna template with mutated oligo(u)
sequence . SNAP
output
|
|
6t0s
|
viral protein |
cryo-EM (3.04 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell,
181, 877. doi: 10.1016/j.cell.2020.03.061.
|
Bat influenza a polymerase stuttering complex using
44-mer vrna template with intact oligo(u) sequence .
SNAP output
|
|
6t0u
|
viral protein |
cryo-EM (3.12 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell,
181, 877. doi: 10.1016/j.cell.2020.03.061.
|
Bat influenza a polymerase product dissociation complex
using 44-mer vrna template with intact oligo(u)
sequence . SNAP
output
|
|
6t0v
|
viral protein |
cryo-EM (3.02 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell,
181, 877. doi: 10.1016/j.cell.2020.03.061.
|
Bat influenza a polymerase elongation complex with
incoming utp analogue (complete polymerase) . SNAP output
|
|
6t0w
|
viral protein |
cryo-EM (3.18 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell,
181, 877. doi: 10.1016/j.cell.2020.03.061.
|
Human influenza b polymerase recycling complex .
SNAP output
|
|
6t2c
|
viral protein |
cryo-EM (3.52 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell,
181, 877. doi: 10.1016/j.cell.2020.03.061.
|
Bat influenza a polymerase recycling complex . SNAP output
|
|
6t34
|
virus |
cryo-EM (5.2 Å) |
Cuesta R, Yuste-Calvo C, Gil-Carton D, Sanchez F,
Ponz F, Valle M |
(2019) "Structure
of Turnip mosaic virus and its viral-like
particles." Sci Rep, 9,
15396. doi: 10.1038/s41598-019-51823-4.
|
Atomic model for turnip mosaic virus (tumv) . SNAP output
|
|
6t4q
|
translation |
cryo-EM (2.6 Å) |
Tesina P, Lessen LN, Buschauer R, Cheng J, Wu CC,
Berninghausen O, Buskirk AR, Becker T, Beckmann R, Green
R |
(2020) "Molecular
mechanism of translational stalling by inhibitory codon
combinations and poly(A) tracts." Embo J.,
39, e103365. doi: 10.15252/embj.2019103365.
|
Structure of yeast 80s ribosome stalled on the cga-ccg
inhibitory codon combination. . SNAP output
|
|
6t59
|
ribosome |
cryo-EM (3.11 Å) |
Lin Z, Gasic I, Chandrasekaran V, Peters N, Shao S,
Mitchison TJ, Hegde RS |
(2020) "TTC5
mediates autoregulation of tubulin via mRNA
degradation." Science,
367, 100-104. doi: 10.1126/science.aaz4352.
|
Structure of rabbit 80s ribosome translating
beta-tubulin in complex with tetratricopeptide protein
5 and nascent chain-associated complex . SNAP output
|
|
6t7i
|
translation |
cryo-EM (3.2 Å) |
Tesina P, Lessen LN, Buschauer R, Cheng J, Wu CC,
Berninghausen O, Buskirk AR, Becker T, Beckmann R, Green
R |
(2020) "Molecular
mechanism of translational stalling by inhibitory codon
combinations and poly(A) tracts." Embo J.,
39, e103365. doi: 10.15252/embj.2019103365.
|
Structure of yeast 80s ribosome stalled on the cga-cga
inhibitory codon combination. . SNAP output
|
|
6t7t
|
translation |
cryo-EM (3.1 Å) |
Tesina P, Lessen LN, Buschauer R, Cheng J, Wu CC,
Berninghausen O, Buskirk AR, Becker T, Beckmann R, Green
R |
(2020) "Molecular
mechanism of translational stalling by inhibitory codon
combinations and poly(A) tracts." Embo J.,
39, e103365. doi: 10.15252/embj.2019103365.
|
Structure of yeast 80s ribosome stalled on poly(a)
tract. . SNAP output
|
|
6t83
|
translation |
cryo-EM (4.0 Å) |
Tesina P, Lessen LN, Buschauer R, Cheng J, Wu CC,
Berninghausen O, Buskirk AR, Becker T, Beckmann R, Green
R |
(2020) "Molecular
mechanism of translational stalling by inhibitory codon
combinations and poly(A) tracts." Embo J.,
39, e103365. doi: 10.15252/embj.2019103365.
|
Structure of yeast disome (di-ribosome) stalled on
poly(a) tract. . SNAP
output
|
|
6tb3
|
translation |
cryo-EM (2.8 Å) |
Buschauer R, Matsuo Y, Sugiyama T, Chen YH, Alhusaini
N, Sweet T, Ikeuchi K, Cheng J, Matsuki Y, Nobuta R,
Gilmozzi A, Berninghausen O, Tesina P, Becker T, Coller
J, Inada T, Beckmann R |
(2020) "The
Ccr4-Not complex monitors the translating ribosome for
codon optimality." Science,
368. doi: 10.1126/science.aay6912.
|
Yeast 80s ribosome in complex with the not5 subunit of
the ccr4-not complex . SNAP output
|
|
6tbv
|
ribosome |
cryo-EM (2.7 Å) |
Herrero Del Valle A, Seip B, Cervera-Marzal I,
Sacheau G, Seefeldt AC, Innis CA |
(2020) "Ornithine
capture by a translating ribosome controls bacterial
polyamine synthesis." Nat Microbiol,
5, 554-561. doi: 10.1038/s41564-020-0669-1.
|
cryo-EM structure of an escherichia coli ribosome-spefl
complex stalled in response to l-ornithine (replicate
2) . SNAP output
|
|
6tc3
|
ribosome |
cryo-EM (2.7 Å) |
Herrero Del Valle A, Seip B, Cervera-Marzal I,
Sacheau G, Seefeldt AC, Innis CA |
(2020) "Ornithine
capture by a translating ribosome controls bacterial
polyamine synthesis." Nat Microbiol,
5, 554-561. doi: 10.1038/s41564-020-0669-1.
|
cryo-EM structure of an escherichia coli ribosome-spefl
complex stalled in response to l-ornithine (replicate
1) . SNAP output
|
|
6th6
|
ribosome |
cryo-EM (2.55 Å) |
Sas-Chen A, Thomas JM, Matzov D, Taoka M, Nance KD,
Nir R, Bryson KM, Shachar R, Liman GLS, Burkhart BW,
Gamage ST, Nobe Y, Briney CA, Levy MJ, Fuchs RT, Robb GB,
Hartmann J, Sharma S, Lin Q, Florens L, Washburn MP,
Isobe T, Santangelo TJ, Shalev-Benami M, Meier JL,
Schwartz S |
(2020) "Dynamic
RNA acetylation revealed by quantitative
cross-evolutionary mapping." Nature,
583, 638-643. doi: 10.1038/s41586-020-2418-2.
|
cryo-EM structure of t. kodakarensis 70s ribosome .
SNAP output
|
|
6thn
|
virus |
cryo-EM (2.6 Å) |
Chandler-Bostock R, Mata CP, Bingham RJ, Dykeman EC,
Meng B, Tuthill TJ, Rowlands DJ, Ranson NA, Twarock R,
Stockley PG |
(2020) "Assembly
of infectious enteroviruses depends on multiple,
conserved genomic RNA-coat protein contacts."
Plos Pathog., 16, e1009146.
doi: 10.1371/journal.ppat.1009146.
|
Multiple genomic RNA-coat protein contacts play vital
roles in the assembly of infectious enterovirus-e
symmetry expansion+2fold focused classification .
SNAP output
|
|
6tmf
|
ribosome |
cryo-EM (2.8 Å) |
Nurenberg-Goloub E, Kratzat H, Heinemann H, Heuer A,
Kotter P, Berninghausen O, Becker T, Tampe R, Beckmann
R |
(2020) "Molecular
analysis of the ribosome recycling factor ABCE1 bound
to the 30S post-splitting complex." Embo
J., 39, e103788. doi: 10.15252/embj.2019103788.
|
Structure of an archaeal abce1-bound ribosomal
post-splitting complex . SNAP output
|
|
6tnn
|
ribosomal protein |
cryo-EM (3.07 Å) |
Oerum S, Dendooven T, Catala M, Gilet L, Degut C,
Trinquier A, Bourguet M, Barraud P, Cianferani S, Luisi
BF, Condon C, Tisne C |
(2020) "Structures
of B. subtilis Maturation RNases Captured on 50S
Ribosome with Pre-rRNAs." Mol.Cell,
80, 227. doi: 10.1016/j.molcel.2020.09.008.
|
Mini-rnase iii (mini-iii) bound to 50s ribosome with
precursor 23s rrna . SNAP output
|
|
6tnu
|
translation |
cryo-EM (3.1 Å) |
Buschauer R, Matsuo Y, Sugiyama T, Chen YH, Alhusaini
N, Sweet T, Ikeuchi K, Cheng J, Matsuki Y, Nobuta R,
Gilmozzi A, Berninghausen O, Tesina P, Becker T, Coller
J, Inada T, Beckmann R |
(2020) "The
Ccr4-Not complex monitors the translating ribosome for
codon optimality." Science,
368. doi: 10.1126/science.aay6912.
|
Yeast 80s ribosome in complex with eif5a and decoding
a-site and p-site trnas. . SNAP output
|
|
6tph
|
RNA |
NMR |
Ahmed M, Marchanka A, Carlomagno T |
(2020) "Structure
of a Protein-RNA Complex by Solid-State NMR
Spectroscopy." Angew.Chem.Int.Ed.Engl.,
59, 6866-6873. doi: 10.1002/anie.201915465.
|
Structure of a protein-RNA complex by ssnmr . SNAP output
|
|
6tpq
|
ribosomal protein |
cryo-EM (3.07 Å) |
Oerum S, Dendooven T, Catala M, Gilet L, Degut C,
Trinquier A, Bourguet M, Barraud P, Cianferani S, Luisi
BF, Condon C, Tisne C |
(2020) "Structures
of B. subtilis Maturation RNases Captured on 50S
Ribosome with Pre-rRNAs." Mol.Cell,
80, 227. doi: 10.1016/j.molcel.2020.09.008.
|
Rnase m5 bound to 50s ribosome with precursor 5s rrna .
SNAP output
|
|
6tqa
|
RNA binding protein |
X-ray (2.4 Å) |
Binas O, Tants JN, Peter SA, Janowski R, Davydova E,
Braun J, Niessing D, Schwalbe H, Weigand JE, Schlundt
A |
(2020) "Structural
basis for the recognition of transiently structured
AU-rich elements by Roquin." Nucleic Acids
Res., 48, 7385-7403. doi:
10.1093/nar/gkaa465.
|
X-ray structure of roquin roq domain in complex with a
ucp3 cde2 sl RNA motif . SNAP output
|
|
6tqb
|
RNA binding protein |
X-ray (1.6 Å) |
Binas O, Tants JN, Peter SA, Janowski R, Davydova E,
Braun J, Niessing D, Schwalbe H, Weigand JE, Schlundt
A |
(2020) "Structural
basis for the recognition of transiently structured
AU-rich elements by Roquin." Nucleic Acids
Res., 48, 7385-7403. doi:
10.1093/nar/gkaa465.
|
X-ray structure of roquin roq domain in complex with a
ucp3 cde1 sl RNA motif . SNAP output
|
|
6tw1
|
viral protein |
cryo-EM (2.7 Å) |
Wandzik JM, Kouba T, Karuppasamy M, Pflug A, Drncova
P, Provaznik J, Azevedo N, Cusack S |
(2020) "A
Structure-Based Model for the Complete Transcription
Cycle of Influenza Polymerase." Cell. doi:
10.1016/j.cell.2020.03.061.
|
Bat influenza a polymerase termination complex with
pyrophosphate using 44-mer vrna template with mutated
oligo(u) sequence . SNAP
output
|
|
6ty9
|
viral protein, transferase-RNA |
cryo-EM (2.9 Å) |
Cui Y, Zhang Y, Zhou K, Sun J, Zhou ZH |
(2019) "Conservative
transcription in three steps visualized in a
double-stranded RNA virus."
Nat.Struct.Mol.Biol., 26,
1023-1034. doi: 10.1038/s41594-019-0320-0.
|
In situ structure of bmcpv RNA dependent RNA polymerase
at initiation state . SNAP output
|
|
6tz1
|
viral protein, transferase-RNA |
cryo-EM (3.4 Å) |
Cui Y, Zhang Y, Zhou K, Sun J, Zhou ZH |
(2019) "Conservative
transcription in three steps visualized in a
double-stranded RNA virus."
Nat.Struct.Mol.Biol., 26,
1023-1034. doi: 10.1038/s41594-019-0320-0.
|
In situ structure of bmcpv RNA-dependent RNA polymerase
at early-elongation state . SNAP output
|
|
6tz2
|
viral protein, transferase-RNA |
cryo-EM (3.5 Å) |
Cui Y, Zhang Y, Zhou K, Sun J, Zhou ZH |
(2019) "Conservative
transcription in three steps visualized in a
double-stranded RNA virus."
Nat.Struct.Mol.Biol., 26,
1023-1034. doi: 10.1038/s41594-019-0320-0.
|
In situ structure of bmcpv RNA-dependent RNA polymerase
at elongation state . SNAP output
|
|
6u48
|
ribosome-inhibitor |
cryo-EM (2.87 Å) |
Travin DY, Watson ZL, Metelev M, Ward FR, Osterman
IA, Khven IM, Khabibullina NF, Serebryakova M, Mergaert
P, Polikanov YS, Cate JHD, Severinov K |
(2019) "Structure
of ribosome-bound azole-modified peptide phazolicin
rationalizes its species-specific mode of bacterial
translation inhibition." Nat Commun,
10, 4563. doi: 10.1038/s41467-019-12589-5.
|
E. coli 50s with phazolicin (phz) bound in exit tunnel
. SNAP output
|
|
6u6y
|
hydrolase |
X-ray (2.47 Å) |
Yu CH, Bhattacharya A, Persaud M, Taylor AB, Wang Z,
Bulnes-Ramos A, Xu J, Selyutina A, Martinez-Lopez A, Cano
K, Demeler B, Kim B, Hardies SC, Diaz-Griffero F, Ivanov
DN |
(2021) "Nucleic
acid binding by SAMHD1 contributes to the
antiretroviral activity and is enhanced by the GpsN
modification." Nat Commun,
12, 731. doi: 10.1038/s41467-021-21023-8.
|
Human samhd1 bound to ribo(cgccu)-oligonucleotide .
SNAP output
|
|
6u8d
|
RNA-immune system |
X-ray (1.807 Å) |
Koirala D, Lewicka A, Koldobskaya Y, Huang H,
Piccirilli JA |
(2020) "Synthetic
Antibody Binding to a Preorganized RNA Domain of
Hepatitis C Virus Internal Ribosome Entry Site Inhibits
Translation." Acs Chem.Biol.,
15, 205-216. doi: 10.1021/acschembio.9b00785.
|
Crystal structure of hepatitis c virus ires junction
iiiabc in complex with fab hcv2 . SNAP output
|
|
6u8k
|
RNA-immune system |
X-ray (2.75 Å) |
Koirala D, Lewicka A, Koldobskaya Y, Huang H,
Piccirilli JA |
(2020) "Synthetic
Antibody Binding to a Preorganized RNA Domain of
Hepatitis C Virus Internal Ribosome Entry Site Inhibits
Translation." Acs Chem.Biol.,
15, 205-216. doi: 10.1021/acschembio.9b00785.
|
Crystal structure of hepatitis c virus ires junction
iiiabc in complex with fab hcv3 . SNAP output
|
|
6u9x
|
RNA binding protein-RNA |
X-ray (2.6 Å) |
Schumacher MA, Henderson M, Zeng W |
(2020) "Structures
of MERS1, the 5' processing enzyme of mitochondrial
mRNAs inTrypanosoma brucei." Rna,
26, 69-82. doi: 10.1261/rna.072231.119.
|
Structure of t. brucei mers1-RNA complex . SNAP output
|
|
6ucq
|
ribosome |
X-ray (3.5 Å) |
Zhou D, Tanzawa T, Lin J, Gagnon MG |
(2020) "Structural
basis for ribosome recycling by RRF and tRNA."
Nat.Struct.Mol.Biol., 27,
25-32. doi: 10.1038/s41594-019-0350-7.
|
Crystal structure of the thermus thermophilus 70s
ribosome recycling complex . SNAP output
|
|
6uej
|
antiviral protein |
X-ray (2.21 Å) |
Meagher JL, Takata M, Goncalves-Carneiro D, Keane SC,
Rebendenne A, Ong H, Orr VK, MacDonald MR, Stuckey JA,
Bieniasz PD, Smith JL |
(2019) "Structure
of the zinc-finger antiviral protein in complex with
RNA reveals a mechanism for selective targeting of
CG-rich viral sequences."
Proc.Natl.Acad.Sci.USA, 116,
24303-24309. doi: 10.1073/pnas.1913232116.
|
Crystal structure of human zinc finger antiviral
protein bound to RNA . SNAP output
|
|
6uo1
|
ribosome |
X-ray (2.95 Å) |
Eyler DE, Franco MK, Batool Z, Wu MZ, Dubuke ML,
Dobosz-Bartoszek M, Jones JD, Polikanov YS, Roy B,
Koutmou KS |
(2019) "Pseudouridinylation
of mRNA coding sequences alters translation."
Proc.Natl.Acad.Sci.USA, 116,
23068-23074. doi: 10.1073/pnas.1821754116.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with mrna (containing pseudouridine
at the first position of the codon) and deacylated a-,
p-, and e-site trnas at 2.95a resolution . SNAP output
|
|
6uro
|
RNA binding protein-RNA |
cryo-EM (3.6 Å) |
Zhang Y, Sun Y, Shi Y, Walz T, Tong L |
(2020) "Structural
Insights into the Human Pre-mRNA 3'-End Processing
Machinery." Mol.Cell, 77,
800. doi: 10.1016/j.molcel.2019.11.005.
|
cryo-EM structure of human cpsf160-wdr33-cpsf30-pas
RNA-cstf77 complex . SNAP output
|
|
6uv1
|
RNA binding protein-RNA |
X-ray (2.307 Å) |
Ngo TD, Partin AC, Nam Y |
(2019) "RNA
Specificity and Autoregulation of DDX17, a Modulator of
MicroRNA Biogenesis." Cell Rep,
29, 4024-4035.e5. doi: 10.1016/j.celrep.2019.11.059.
|
Crystal structure of RNA helicase ddx17 in complex of
ru10 RNA . SNAP
output
|
|
6uv2
|
RNA binding protein-RNA |
X-ray (1.894 Å) |
Ngo TD, Partin AC, Nam Y |
(2019) "RNA
Specificity and Autoregulation of DDX17, a Modulator of
MicroRNA Biogenesis." Cell Rep,
29, 4024-4035.e5. doi: 10.1016/j.celrep.2019.11.059.
|
Crystal structure of the core domain of RNA helicase
ddx17 with RNA pri-125a-oligo1 . SNAP output
|
|
6uv3
|
RNA binding protein-RNA |
X-ray (1.597 Å) |
Ngo TD, Partin AC, Nam Y |
(2019) "RNA
Specificity and Autoregulation of DDX17, a Modulator of
MicroRNA Biogenesis." Cell Rep,
29, 4024-4035.e5. doi: 10.1016/j.celrep.2019.11.059.
|
Crystal structure of the core domain of RNA helicase
ddx17 with RNA pri-125a-oligo2 . SNAP output
|
|
6uv4
|
RNA binding protein-RNA |
X-ray (1.7 Å) |
Ngo TD, Partin AC, Nam Y |
(2019) "RNA
Specificity and Autoregulation of DDX17, a Modulator of
MicroRNA Biogenesis." Cell Rep,
29, 4024-4035.e5. doi: 10.1016/j.celrep.2019.11.059.
|
Crystal structure of the core domain of RNA helicase
ddx17 with RNA pri-18a-oligo1 . SNAP output
|
|
6v39
|
ribosome |
cryo-EM (3.04 Å) |
Morgan CE, Huang W, Rudin SD, Taylor DJ, Kirby JE,
Bonomo RA, Yu EW |
(2020) "Cryo-electron
Microscopy Structure of the Acinetobacter baumannii 70S
Ribosome and Implications for New Antibiotic
Development." Mbio, 11.
doi: 10.1128/mBio.03117-19.
|
cryo-EM structure of the acinetobacter baumannii
ribosome: 70s with p-site trna . SNAP output
|
|
6v3a
|
ribosome |
cryo-EM (2.82 Å) |
Morgan CE, Huang W, Rudin SD, Taylor DJ, Kirby JE,
Bonomo RA, Yu EW |
(2020) "Cryo-electron
Microscopy Structure of the Acinetobacter baumannii 70S
Ribosome and Implications for New Antibiotic
Development." Mbio, 11.
doi: 10.1128/mBio.03117-19.
|
cryo-EM structure of the acinetobacter baumannii
ribosome: 70s with e-site trna . SNAP output
|
|
6v3b
|
ribosome |
cryo-EM (2.91 Å) |
Morgan CE, Huang W, Rudin SD, Taylor DJ, Kirby JE,
Bonomo RA, Yu EW |
(2020) "Cryo-electron
Microscopy Structure of the Acinetobacter baumannii 70S
Ribosome and Implications for New Antibiotic
Development." Mbio, 11.
doi: 10.1128/mBio.03117-19.
|
cryo-EM structure of the acinetobacter baumannii
ribosome: 70s in empty state . SNAP output
|
|
6v3d
|
ribosome |
cryo-EM (2.95 Å) |
Morgan CE, Huang W, Rudin SD, Taylor DJ, Kirby JE,
Bonomo RA, Yu EW |
(2020) "Cryo-electron
Microscopy Structure of the Acinetobacter baumannii 70S
Ribosome and Implications for New Antibiotic
Development." Mbio, 11.
doi: 10.1128/mBio.03117-19.
|
cryo-EM structure of the acinetobacter baumannii
ribosome: 50s subunit . SNAP output
|
|
6v3e
|
ribosome |
cryo-EM (4.4 Å) |
Morgan CE, Huang W, Rudin SD, Taylor DJ, Kirby JE,
Bonomo RA, Yu EW |
(2020) "Cryo-electron
Microscopy Structure of the Acinetobacter baumannii 70S
Ribosome and Implications for New Antibiotic
Development." Mbio, 11.
doi: 10.1128/mBio.03117-19.
|
cryo-EM structure of the acinetobacter baumannii
ribosome: 30s subunit . SNAP output
|
|
6v4x
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Sun Y, Zhang Y, Aik WS, Yang XC, Marzluff WF, Walz T,
Dominski Z, Tong L |
(2020) "Structure
of an active human histone pre-mRNA 3'-end processing
machinery." Science, 367,
700-703. doi: 10.1126/science.aaz7758.
|
cryo-EM structure of an active human histone pre-mrna
3'-end processing machinery at 3.2 angstrom resolution
. SNAP output
|
|
6v5b
|
RNA binding protein-RNA |
cryo-EM (3.7 Å) |
Partin AC, Zhang K, Jeong BC, Herrell E, Li S, Chiu
W, Nam Y |
(2020) "Cryo-EM
Structures of Human Drosha and DGCR8 in Complex with
Primary MicroRNA." Mol.Cell,
78, 411. doi: 10.1016/j.molcel.2020.02.016.
|
Human drosha and dgcr8 in complex with primary microrna
(mp-RNA complex) - active state . SNAP output
|
|
6v5c
|
RNA binding protein-RNA |
cryo-EM (4.4 Å) |
Partin AC, Zhang K, Jeong BC, Herrell E, Li S, Chiu
W, Nam Y |
(2020) "Cryo-EM
Structures of Human Drosha and DGCR8 in Complex with
Primary MicroRNA." Mol.Cell,
78, 411. doi: 10.1016/j.molcel.2020.02.016.
|
Human drosha and dgcr8 in complex with primary microrna
(mp-RNA complex) - partially docked state . SNAP output
|
|
6v9q
|
immune system |
cryo-EM (2.9 Å) |
Jia N, Xie W, de la Cruz MJ, Eng ET, Patel DJ |
(2020) "Structure-function
insights into the initial step of DNA integration by a
CRISPR-Cas-Transposon complex." Cell Res.,
30, 182-184. doi: 10.1038/s41422-019-0272-2.
|
cryo-EM structure of cascade-tniq binary complex .
SNAP output
|
|
6vff
|
hydrolase-RNA |
X-ray (2.8 Å) |
Thuy-Boun AS, Thomas JM, Grajo HL, Palumbo CM, Park
S, Nguyen LT, Fisher AJ, Beal PA |
(2020) "Asymmetric
dimerization of adenosine deaminase acting on RNA
facilitates substrate recognition." Nucleic
Acids Res., 48, 7958-7972. doi:
10.1093/nar/gkaa532.
|
Dimer of human adenosine deaminase acting on dsrna
(adar2) mutant e488q bound to dsrna sequence derived
from human gli1 gene . SNAP output
|
|
6vlz
|
ribosome |
cryo-EM (2.97 Å) |
Koripella RK, Sharma MR, Bhargava K, Datta PP,
Kaushal PS, Keshavan P, Spremulli LL, Banavali NK,
Agrawal RK |
(2020) "Structures
of the human mitochondrial ribosome bound to EF-G1
reveal distinct features of mitochondrial translation
elongation." Nat Commun,
11, 3830. doi: 10.1038/s41467-020-17715-2.
|
Structure of the human mitochondrial ribosome-ef-g1
complex (classi) . SNAP
output
|
|
6vm6
|
hydrolase |
X-ray (2.1 Å) |
Lowey B, Whiteley AT, Keszei AFA, Morehouse BR,
Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P,
Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY,
Kranzusch PJ |
(2020) "CBASS
Immunity Uses CARF-Related Effectors to Sense 3'-5'-
and 2'-5'-Linked Cyclic Oligonucleotide Signals and
Protect Bacteria from Phage Infection."
Cell, 182, 38. doi: 10.1016/j.cell.2020.05.019.
|
Structure of acinetobacter baumannii cap4
saved-carf-domain containing receptor with the cyclic
trinucleotide 2'3'3'-caaa . SNAP output
|
|
6vmi
|
ribosome |
cryo-EM (2.96 Å) |
Koripella RK, Sharma MR, Bhargava K, Datta PP,
Kaushal PS, Keshavan P, Spremulli LL, Banavali NK,
Agrawal RK |
(2020) "Structures
of the human mitochondrial ribosome bound to EF-G1
reveal distinct features of mitochondrial translation
elongation." Nat Commun,
11, 3830. doi: 10.1038/s41467-020-17715-2.
|
Structure of the human mitochondrial ribosome-ef-g1
complex (classiii) . SNAP output
|
|
6vqv
|
RNA binding protein-RNA-inhibitor |
cryo-EM (2.57 Å) |
Zhang K, Wang S, Li S, Zhu Y, Pintilie GD, Mou TC,
Schmid MF, Huang Z, Chiu W |
(2020) "Inhibition
mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F
CRISPR-Cas complex revealed by cryo-EM."
Proc.Natl.Acad.Sci.USA, 117,
7176-7182. doi: 10.1073/pnas.1922638117.
|
Type i-f crispr-csy complex with its inhibitor acrf9 .
SNAP output
|
|
6vqw
|
RNA binding protein-RNA-inhibitor |
cryo-EM (3.42 Å) |
Zhang K, Wang S, Li S, Zhu Y, Pintilie GD, Mou TC,
Schmid MF, Huang Z, Chiu W |
(2020) "Inhibition
mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F
CRISPR-Cas complex revealed by cryo-EM."
Proc.Natl.Acad.Sci.USA, 117,
7176-7182. doi: 10.1073/pnas.1922638117.
|
Type i-f crispr-csy complex with its inhibitor acrf8 .
SNAP output
|
|
6vqx
|
RNA binding protein-RNA-inhibitor |
cryo-EM (3.15 Å) |
Zhang K, Wang S, Li S, Zhu Y, Pintilie GD, Mou TC,
Schmid MF, Huang Z, Chiu W |
(2020) "Inhibition
mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F
CRISPR-Cas complex revealed by cryo-EM."
Proc.Natl.Acad.Sci.USA, 117,
7176-7182. doi: 10.1073/pnas.1922638117.
|
Type i-f crispr-csy complex with its inhibitor acrf6 .
SNAP output
|
|
6vrb
|
immune system |
cryo-EM (3.0 Å) |
Meeske AJ, Jia N, Cassel AK, Kozlova A, Liao J,
Wiedmann M, Patel DJ, Marraffini LA |
(2020) "A
phage-encoded anti-CRISPR enables complete evasion of
type VI-A CRISPR-Cas immunity." Science,
369, 54-59. doi: 10.1126/science.abb6151.
|
cryo-EM structure of acrvia1-cas13(crrna) complex .
SNAP output
|
|
6vrc
|
immune system |
cryo-EM (3.2 Å) |
Meeske AJ, Jia N, Cassel AK, Kozlova A, Liao J,
Wiedmann M, Patel DJ, Marraffini LA |
(2020) "A
phage-encoded anti-CRISPR enables complete evasion of
type VI-A CRISPR-Cas immunity." Science,
369, 54-59. doi: 10.1126/science.abb6151.
|
cryo-EM structure of cas13(crrna) . SNAP output
|
|
6vwl
|
ribosome |
cryo-EM (3.1 Å) |
Bao C, Loerch S, Ling C, Korostelev AA, Grigorieff N,
Ermolenko DN |
(2020) "mRNA
stem-loops can pause the ribosome by hindering A-site
tRNA binding." Elife, 9.
doi: 10.7554/eLife.55799.
|
70s ribosome bound to hiv frameshifting stem-loop (fss)
and p-e trna (rotated conformation) . SNAP output
|
|
6vwm
|
ribosome |
cryo-EM (3.4 Å) |
Bao C, Loerch S, Ling C, Korostelev AA, Grigorieff N,
Ermolenko DN |
(2020) "mRNA
stem-loops can pause the ribosome by hindering A-site
tRNA binding." Elife, 9.
doi: 10.7554/eLife.55799.
|
70s ribosome bound to hiv frameshifting stem-loop (fss)
and p-site trna (non-rotated conformation, structure i)
. SNAP output
|
|
6vwn
|
ribosome |
cryo-EM (3.4 Å) |
Bao C, Loerch S, Ling C, Korostelev AA, Grigorieff N,
Ermolenko DN |
(2020) "mRNA
stem-loops can pause the ribosome by hindering A-site
tRNA binding." Elife, 9.
doi: 10.7554/eLife.55799.
|
70s ribosome bound to hiv frameshifting stem-loop (fss)
and p-site trna (non-rotated conformation, structure
ii) . SNAP output
|
|
6w11
|
transcription |
X-ray (2.46 Å) |
Charbonneau AA, Eckert DM, Gauvin CC, Lintner NG,
Lawrence CM |
(2021) "Cyclic
Tetra-Adenylate (cA 4 ) Recognition by Csa3;
Implications for an Integrated Class 1 CRISPR-Cas
Immune Response in Saccharolobus solfataricus."
Biomolecules, 11. doi:
10.3390/biom11121852.
|
The structure of sulfolobus solfataricus csa3 in
complex with cyclic tetraadenylate (ca4) . SNAP output
|
|
6w1x
|
immune system-RNA |
cryo-EM (3.9 Å) |
Hirschi M, Lu WT, Santiago-Frangos A, Wilkinson R,
Golden SM, Davidson AR, Lander GC, Wiedenheft B |
(2020) "AcrIF9
tethers non-sequence specific dsDNA to the CRISPR
RNA-guided surveillance complex." Nat
Commun, 11, 2730. doi: 10.1038/s41467-020-16512-1.
|
cryo-EM structure of anti-crispr acrif9, bound to the
type i-f crrna-guided crispr surveillance complex .
SNAP output
|
|
6w2s
|
ribosome-translation |
cryo-EM (3.47 Å) |
Neupane R, Pisareva VP, Rodriguez CF, Pisarev AV,
Fernandez IS |
(2020) "A
complex IRES at the 5'-UTR of a viral mRNA assembles a
functional 48S complex via an uAUG intermediate."
Elife, 9. doi: 10.7554/eLife.54575.
|
Structure of the cricket paralysis virus 5-utr ires
(crpv 5-utr-ires) bound to the small ribosomal subunit
in the open state (class 1) . SNAP output
|
|
6w2t
|
ribosome |
cryo-EM (3.36 Å) |
Neupane R, Pisareva VP, Rodriguez CF, Pisarev AV,
Fernandez IS |
(2020) "A
complex IRES at the 5'-UTR of a viral mRNA assembles a
functional 48S complex via an uAUG intermediate."
Elife, 9. doi: 10.7554/eLife.54575.
|
Structure of the cricket paralysis virus 5-utr ires
(crpv 5-utr-ires) bound to the small ribosomal subunit
in the closed state (class 2) . SNAP output
|
|
6w62
|
hydrolase-DNA-RNA |
cryo-EM (3.9 Å) |
Zhang H, Li Z, Xiao R, Chang L |
(2020) "Mechanisms
for target recognition and cleavage by the Cas12i
RNA-guided endonuclease."
Nat.Struct.Mol.Biol., 27,
1069-1076. doi: 10.1038/s41594-020-0499-0.
|
cryo-EM structure of cas12i-crrna complex . SNAP output
|
|
6w6k
|
ribosome |
cryo-EM (3.6 Å) |
Jahagirdar D, Jha V, Basu K, Gomez-Blanco J, Vargas
J, Ortega J |
(2020) "Alternative
conformations and motions adopted by 30S ribosomal
subunits visualized by cryo-electron microscopy."
Rna, 26, 2017-2030. doi:
10.1261/rna.075846.120.
|
30s-activated-high-mg2+ . SNAP output
|
|
6w6l
|
ribosome-protein transport |
cryo-EM (3.84 Å) |
McGilvray PT, Anghel SA, Sundaram A, Zhong F, Trnka
MJ, Fuller JR, Hu H, Burlingame AL, Keenan RJ |
(2020) "An ER
translocon for multi-pass membrane protein
biogenesis." Elife, 9.
doi: 10.7554/eLife.56889.
|
cryo-EM structure of the human ribosome-tmco1
translocon . SNAP
output
|
|
6w6p
|
ribosome |
cryo-EM (2.9 Å) |
Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory
ST, Murray BE, Krause KL, Khayat R, Jogl G |
(2020) "Cryo-electron
microscopy structure of the 70S ribosome from
Enterococcus faecalis." Sci Rep,
10, 16301. doi: 10.1038/s41598-020-73199-6.
|
Multibody refinement of 70s ribosome from enterococcus
faecalis . SNAP
output
|
|
6w6v
|
hydrolase |
cryo-EM (3.0 Å) |
Perederina A, Li D, Lee H, Bator C, Berezin I,
Hafenstein SL, Krasilnikov AS |
(2020) "Cryo-EM
structure of catalytic ribonucleoprotein complex RNase
MRP." Nat Commun, 11,
3474. doi: 10.1038/s41467-020-17308-z.
|
Structure of yeast rnase mrp holoenzyme . SNAP output
|
|
6w77
|
ribosome |
cryo-EM (3.6 Å) |
Jahagirdar D, Jha V, Basu K, Gomez-Blanco J, Vargas
J, Ortega J |
(2020) "Alternative
conformations and motions adopted by 30S ribosomal
subunits visualized by cryo-electron microscopy."
Rna, 26, 2017-2030. doi:
10.1261/rna.075846.120.
|
30s-inactivated-high-mg2+ class a . SNAP output
|
|
6w7m
|
ribosome |
cryo-EM (3.8 Å) |
Jahagirdar D, Jha V, Basu K, Gomez-Blanco J, Vargas
J, Ortega J |
(2020) "Alternative
conformations and motions adopted by 30S ribosomal
subunits visualized by cryo-electron microscopy."
Rna, 26, 2017-2030. doi:
10.1261/rna.075846.120.
|
30s-inactive-high-mg2+ + carbon layer . SNAP output
|
|
6w7n
|
ribosome |
cryo-EM (3.4 Å) |
Jahagirdar D, Jha V, Basu K, Gomez-Blanco J, Vargas
J, Ortega J |
(2020) "Alternative
conformations and motions adopted by 30S ribosomal
subunits visualized by cryo-electron microscopy."
Rna, 26, 2017-2030. doi:
10.1261/rna.075846.120.
|
30s-inactive-low-mg2+ class a . SNAP output
|
|
6w7w
|
ribosome |
cryo-EM (3.9 Å) |
Jahagirdar D, Jha V, Basu K, Gomez-Blanco J, Vargas
J, Ortega J |
(2020) "Alternative
conformations and motions adopted by 30S ribosomal
subunits visualized by cryo-electron microscopy."
Rna, 26, 2017-2030. doi:
10.1261/rna.075846.120.
|
30s-inactive-low-mg2+ class b . SNAP output
|
|
6wan
|
hydrolase |
X-ray (2.4 Å) |
Lowey B, Whiteley AT, Keszei AFA, Morehouse BR,
Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P,
Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY,
Kranzusch PJ |
(2020) "CBASS
Immunity Uses CARF-Related Effectors to Sense 3'-5'-
and 2'-5'-Linked Cyclic Oligonucleotide Signals and
Protect Bacteria from Phage Infection."
Cell, 182, 38. doi: 10.1016/j.cell.2020.05.019.
|
Structure of acinetobacter baumannii cap4
saved-carf-domain containing receptor with the cyclic
trinucleotide 3'3'3'-caaa . SNAP output
|
|
6wd0
|
ribosome |
cryo-EM (3.0 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure i-a) .
SNAP output
|
|
6wd1
|
ribosome |
cryo-EM (3.3 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure i-b) .
SNAP output
|
|
6wd2
|
ribosome-RNA |
cryo-EM (3.6 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure ii-a) .
SNAP output
|
|
6wd3
|
ribosome |
cryo-EM (3.6 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure ii-b1)
. SNAP output
|
|
6wd4
|
ribosome |
cryo-EM (3.7 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure ii-b2)
. SNAP output
|
|
6wd5
|
ribosome |
cryo-EM (3.6 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure ii-c1)
. SNAP output
|
|
6wd6
|
ribosome |
cryo-EM (3.7 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure ii-c2)
. SNAP output
|
|
6wd7
|
ribosome |
cryo-EM (3.9 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure ii-d) .
SNAP output
|
|
6wd8
|
ribosome-RNA |
cryo-EM (3.7 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure iii-a)
. SNAP output
|
|
6wd9
|
ribosome-RNA |
cryo-EM (3.7 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure iii-b)
. SNAP output
|
|
6wda
|
ribosome-RNA |
cryo-EM (3.8 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure iii-c)
. SNAP output
|
|
6wdb
|
ribosome |
cryo-EM (4.0 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure iv-a) .
SNAP output
|
|
6wdc
|
ribosome |
cryo-EM (4.2 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure iv-b) .
SNAP output
|
|
6wdd
|
ribosome |
cryo-EM (3.2 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure v-a) .
SNAP output
|
|
6wde
|
ribosome |
cryo-EM (3.0 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure v-b) .
SNAP output
|
|
6wdf
|
ribosome |
cryo-EM (3.3 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure vi-a) .
SNAP output
|
|
6wdg
|
ribosome |
cryo-EM (3.3 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (cognate structure vi-b) .
SNAP output
|
|
6wdh
|
ribosome |
cryo-EM (4.3 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (non-cognate structure
iv-b1) . SNAP output
|
|
6wdi
|
ribosome |
cryo-EM (4.0 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (non-cognate structure
iv-b2) . SNAP output
|
|
6wdj
|
ribosome |
cryo-EM (3.7 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (non-cognate structure
v-a1) . SNAP output
|
|
6wdk
|
ribosome-RNA |
cryo-EM (3.6 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (non-cognate structure
v-a2) . SNAP output
|
|
6wdl
|
ribosome |
cryo-EM (3.7 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (non-cognate structure
v-b1) . SNAP output
|
|
6wdm
|
ribosome |
cryo-EM (3.6 Å) |
Loveland AB, Demo G, Korostelev AA |
(2020) "Cryo-EM
of elongating ribosome with EF-Tu•GTP elucidates tRNA
proofreading." Nature,
584, 640-645. doi: 10.1038/s41586-020-2447-x.
|
cryo-EM of elongating ribosome with ef-tu*gtp
elucidates trna proofreading (non-cognate structure
v-b2) . SNAP output
|
|
6wdr
|
ribosome |
cryo-EM (3.7 Å) |
Rai J, Parker MD, Huang H, Choy S, Ghalei H, Johnson
MC, Karbstein K, Stroupe ME |
(2021) "An open
interface in the pre-80S ribosome coordinated by
ribosome assembly factors Tsr1 and Dim1 enables
temporal regulation of Fap7." Rna,
27, 221-233. doi: 10.1261/rna.077610.120.
|
Subunit joining exposes nascent pre-40s rrna for
processing and quality control . SNAP output
|
|
6wlh
|
transcription |
NMR |
Nishikawa T, Wojciak JM, Dyson HJ, Wright PE |
(2020) "RNA
Binding by the KTS Splice Variants of Wilms' Tumor
Suppressor Protein WT1." Biochemistry,
59, 3889-3901. doi: 10.1021/acs.biochem.0c00602.
|
RNA complex of wt1 zinc finger transcription factor .
SNAP output
|
|
6wnt
|
ribosome |
cryo-EM (3.1 Å) |
Huang S, Aleksashin NA, Loveland AB, Klepacki D,
Reier K, Kefi A, Szal T, Remme J, Jaeger L,
Vazquez-Laslop N, Korostelev AA, Mankin AS |
(2020) "Ribosome
engineering reveals the importance of 5S rRNA autonomy
for ribosome assembly." Nat Commun,
11, 2900. doi: 10.1038/s41467-020-16694-8.
|
50s ribosomal subunit without free 5s rrna and
perturbed ptc . SNAP
output
|
|
6wnv
|
ribosome |
cryo-EM (3.5 Å) |
Huang S, Aleksashin NA, Loveland AB, Klepacki D,
Reier K, Kefi A, Szal T, Remme J, Jaeger L,
Vazquez-Laslop N, Korostelev AA, Mankin AS |
(2020) "Ribosome
engineering reveals the importance of 5S rRNA autonomy
for ribosome assembly." Nat Commun,
11, 2900. doi: 10.1038/s41467-020-16694-8.
|
70s ribosome without free 5s rrna and with a perturbed
ptc . SNAP output
|
|
6wnw
|
ribosome |
cryo-EM (3.2 Å) |
Huang S, Aleksashin NA, Loveland AB, Klepacki D,
Reier K, Kefi A, Szal T, Remme J, Jaeger L,
Vazquez-Laslop N, Korostelev AA, Mankin AS |
(2020) "Ribosome
engineering reveals the importance of 5S rRNA autonomy
for ribosome assembly." Nat Commun,
11, 2900. doi: 10.1038/s41467-020-16694-8.
|
Active 70s ribosome without free 5s rrna and bound with
a- and p- trna . SNAP
output
|
|
6wpi
|
RNA binding protein-RNA |
X-ray (3.02 Å) |
Zhang J, Teramoto T, Qiu C, Wine RN, Gonzalez LE,
Baserga SJ, Tanaka Hall TM |
(2020) "Nop9
recognizes structured and single-stranded RNA elements
of preribosomal RNA." Rna,
26, 1049-1059. doi: 10.1261/rna.075416.120.
|
Crystal structure of nop9 in complex with its1 RNA .
SNAP output
|
|
6wqn
|
ribosome |
cryo-EM (2.9 Å) |
Wright A, Deane-Alder K, Marschall E, Bamert R,
Venugopal H, Lithgow T, Lupton DW, Belousoff MJ |
(2020) "Characterization
of the Core Ribosomal Binding Region for the
Oxazolidone Family of Antibiotics Using Cryo-EM."
Acs Pharmacol Transl Sci, 3,
425-432. doi: 10.1021/acsptsci.0c00041.
|
Structure of the 50s subunit of the ribosome from
methicillin resistant staphylococcus aureus in complex
with the antibiotic, contezolid . SNAP output
|
|
6wqq
|
ribosome |
cryo-EM (3.1 Å) |
Wright A, Deane-Alder K, Marschall E, Bamert R,
Venugopal H, Lithgow T, Lupton DW, Belousoff MJ |
(2020) "Characterization
of the Core Ribosomal Binding Region for the
Oxazolidone Family of Antibiotics Using Cryo-EM."
Acs Pharmacol Transl Sci, 3,
425-432. doi: 10.1021/acsptsci.0c00041.
|
Structure of the 50s subunit of the ribosome from
methicillin resistant staphylococcus aureus in complex
with the antibiotic, radezolid . SNAP output
|
|
6wre
|
hydrolase |
X-ray (2.0 Å) |
Doamekpor SK, Gozdek A, Kwasnik A, Kufel J, Tong
L |
(2020) "A novel
5'-hydroxyl dinucleotide hydrolase activity for the
DXO/Rai1 family of enzymes." Nucleic Acids
Res., 48, 349-358. doi: 10.1093/nar/gkz1107.
|
Crystal structure of mouse dxo in complex with 5'-oh
RNA substrate mimic and calcium ion . SNAP output
|
|
6wrs
|
ribosome |
cryo-EM (3.2 Å) |
Wright A, Deane-Alder K, Marschall E, Bamert R,
Venugopal H, Lithgow T, Lupton DW, Belousoff MJ |
(2020) "Characterization
of the Core Ribosomal Binding Region for the
Oxazolidone Family of Antibiotics Using Cryo-EM."
Acs Pharmacol Transl Sci, 3,
425-432. doi: 10.1021/acsptsci.0c00041.
|
Structure of the 50s subunit of the ribosome from
methicillin resistant staphylococcus aureus in complex
with the antibiotic, tedizolid . SNAP output
|
|
6wru
|
ribosome |
cryo-EM (3.1 Å) |
Wright A, Deane-Alder K, Marschall E, Bamert R,
Venugopal H, Lithgow T, Lupton DW, Belousoff MJ |
(2020) "Characterization
of the Core Ribosomal Binding Region for the
Oxazolidone Family of Antibiotics Using Cryo-EM."
Acs Pharmacol Transl Sci, 3,
425-432. doi: 10.1021/acsptsci.0c00041.
|
Structure of the 50s subunit of the ribosome from
methicillin resistant staphylococcus aureus in complex
with an isomer of the tedizolid . SNAP output
|
|
6wu9
|
ribosome |
cryo-EM (2.9 Å) |
Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory
ST, Murray BE, Krause KL, Khayat R, Jogl G |
(2020) "Cryo-electron
microscopy structure of the 70S ribosome from
Enterococcus faecalis." Sci Rep,
10, 16301. doi: 10.1038/s41598-020-73199-6.
|
50s subunit of 70s ribosome enterococcus faecalis
multibody refinement . SNAP output
|
|
6wua
|
ribosome |
cryo-EM (3.2 Å) |
Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory
ST, Murray BE, Krause KL, Khayat R, Jogl G |
(2020) "Cryo-electron
microscopy structure of the 70S ribosome from
Enterococcus faecalis." Sci Rep,
10, 16301. doi: 10.1038/s41598-020-73199-6.
|
30s subunit (head) of 70s ribosome enterococcus
faecalis multibody refinement . SNAP output
|
|
6wub
|
ribosome |
cryo-EM (3.2 Å) |
Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory
ST, Murray BE, Krause KL, Khayat R, Jogl G |
(2020) "Cryo-electron
microscopy structure of the 70S ribosome from
Enterococcus faecalis." Sci Rep,
10, 16301. doi: 10.1038/s41598-020-73199-6.
|
30s subunit (head) of 70s ribosome enterococcus
faecalis multibody refinement . SNAP output
|
|
6ww6
|
RNA binding protein-RNA |
X-ray (3.8 Å) |
Walshe JL, Siddiquee R, Patel K, Ataide SF |
(2022) "Structural
characterization of the ANTAR antiterminator domain
bound to RNA." Nucleic Acids Res.,
50, 2889-2904. doi: 10.1093/nar/gkac074.
|
Crystal structure of eutv bound to RNA . SNAP output
|
|
6wxq
|
transcription |
X-ray (2.05 Å) |
Xia P, Dutta A, Gupta K, Batish M, Parashar V |
(2022) "Structural
basis of cyclic oligoadenylate binding to the
transcription factor Csa3 outlines cross talk between
type III and type I CRISPR systems."
J.Biol.Chem., 298, 101591.
doi: 10.1016/j.jbc.2022.101591.
|
Crystal structure of crispr-associated transcription
factor csa3 complexed with ca4 . SNAP output
|
|
6wxx
|
DNA binding protein-RNA |
X-ray (3.0 Å) |
Rostol JT, Xie W, Kuryavyi V, Maguin P, Kao K, Froom
R, Patel DJ, Marraffini LA |
(2021) "The
Card1 nuclease provides defence during type III CRISPR
immunity." Nature, 590,
624-629. doi: 10.1038/s41586-021-03206-x.
|
Crystal structure of ca4-activated card1 . SNAP output
|
|
6wxy
|
DNA binding protein-RNA |
X-ray (2.1 Å) |
Rostol JT, Xie W, Kuryavyi V, Maguin P, Kao K, Froom
R, Patel DJ, Marraffini LA |
(2021) "The
Card1 nuclease provides defence during type III CRISPR
immunity." Nature, 590,
624-629. doi: 10.1038/s41586-021-03206-x.
|
Crystal structure of ca6-bound card1 . SNAP output
|
|
6wyv
|
ribosome |
cryo-EM (2.75 Å) |
Li Q, Pellegrino J, Lee DJ, Tran AA, Chaires HA, Wang
R, Park JE, Ji K, Chow D, Zhang N, Brilot AF, Biel JT,
van Zundert G, Borrelli K, Shinabarger D, Wolfe C, Murray
B, Jacobson MP, Muhle E, Chesneau O, Fraser JS, Seiple
IB |
(2020) "Synthetic
group A streptogramin antibiotics that overcome Vat
resistance." Nature, 586,
145-150. doi: 10.1038/s41586-020-2761-3.
|
E. coli 50s ribosome bound to compounds 47 and vs1 .
SNAP output
|
|
6x1b
|
viral protein |
X-ray (1.97 Å) |
Kim Y, Wower J, Maltseva N, Chang C, Jedrzejczak R,
Wilamowski M, Kang S, Nicolaescu V, Randall G, Michalska
K, Joachimiak A |
(2021) "Tipiracil
binds to uridine site and inhibits Nsp15
endoribonuclease NendoU from SARS-CoV-2."
Commun Biol, 4, 193. doi:
10.1038/s42003-021-01735-9.
|
Crystal structure of nsp15 endoribonuclease from sars
cov-2 in the complex with the product nucleotide gpu. .
SNAP output
|
|
6x5m
|
immune system-RNA |
X-ray (2.5 Å) |
Swain M, Ageeli AA, Kasprzak WK, Li M, Miller JT,
Sztuba-Solinska J, Schneekloth JS, Koirala D, Piccirili
J, Fraboni AJ, Murelli RP, Wlodawer A, Shapiro BA, Baird
N, Le Grice SFJ |
(2021) "Dynamic
bulge nucleotides in the KSHV PAN ENE triple helix
provide a unique binding platform for small molecule
ligands." Nucleic Acids Res.,
49, 13179-13193. doi: 10.1093/nar/gkab1170.
|
Crystal structure of a stabilized pan ene bimolecular
triplex with a gc-clamped polya tail, in complex with
fab-bl-3,6. . SNAP
output
|
|
6x5n
|
immune system-RNA |
X-ray (3.3 Å) |
Swain M, Ageeli AA, Kasprzak WK, Li M, Miller JT,
Sztuba-Solinska J, Schneekloth JS, Koirala D, Piccirili
J, Fraboni AJ, Murelli RP, Wlodawer A, Shapiro BA, Baird
N, Le Grice SFJ |
(2021) "Dynamic
bulge nucleotides in the KSHV PAN ENE triple helix
provide a unique binding platform for small molecule
ligands." Nucleic Acids Res.,
49, 13179-13193. doi: 10.1093/nar/gkab1170.
|
Crystal structure of a stabilized pan ene bimolecular
triplex with a gc-clamped polya tail, in complex with
fab-bl-3,6 . SNAP
output
|
|
6xa1
|
ribosome |
cryo-EM (2.8 Å) |
Li W, Chang ST, Ward FR, Cate JHD |
(2020) "Selective
inhibition of human translation termination by a
drug-like compound." Nat Commun,
11, 4941. doi: 10.1038/s41467-020-18765-2.
|
Structure of a drug-like compound stalled human
translation termination complex . SNAP output
|
|
6xe0
|
ribosome |
cryo-EM (6.8 Å) |
Washburn RS, Zuber PK, Sun M, Hashem Y, Shen B, Li W,
Harvey S, Acosta Reyes FJ, Gottesman ME, Knauer SH, Frank
J |
(2020) "Escherichia
coli NusG Links the Lead Ribosome with the
Transcription Elongation Complex."
Iscience, 23, 101352. doi:
10.1016/j.isci.2020.101352.
|
cryo-EM structure of nusg-ctd bound to 70s ribosome
(30s: nusg-ctd fragment) . SNAP output
|
|
6xez
|
transferase-hydrolase-RNA |
cryo-EM (3.5 Å) |
Chen J, Malone B, Llewellyn E, Grasso M, Shelton PMM,
Olinares PDB, Maruthi K, Eng ET, Vatandaslar H, Chait BT,
Kapoor TM, Darst SA, Campbell EA |
(2020) "Structural
Basis for Helicase-Polymerase Coupling in the
SARS-CoV-2 Replication-Transcription Complex."
Cell, 182, 1560-1573.e13.
doi: 10.1016/j.cell.2020.07.033.
|
Structure of sars-cov-2 replication-transcription
complex bound to nsp13 helicase - nsp13(2)-rtc .
SNAP output
|
|
6xh0
|
RNA binding protein-RNA |
X-ray (3.1 Å) |
Chavali SS, Mali SM, Jenkins JL, Fasan R, Wedekind
JE |
(2020) "Co-crystal
structures of HIV TAR RNA bound to lab-evolved proteins
show key roles for arginine relevant to the design of
cyclic peptide TAR inhibitors."
J.Biol.Chem., 295,
16470-16486. doi: 10.1074/jbc.RA120.015444.
|
Co-crystal structure of hiv-1 tar RNA in complex with
lab-evolved rrm tbp6.9 . SNAP output
|
|
6xh1
|
RNA binding protein-RNA |
X-ray (2.601 Å) |
Chavali SS, Mali SM, Jenkins JL, Fasan R, Wedekind
JE |
(2020) "Co-crystal
structures of HIV TAR RNA bound to lab-evolved proteins
show key roles for arginine relevant to the design of
cyclic peptide TAR inhibitors."
J.Biol.Chem., 295,
16470-16486. doi: 10.1074/jbc.RA120.015444.
|
Co-crystal structure of hiv-1 tar RNA in complex with
lab-evolved rrm tbp6.7 mutant . SNAP output
|
|
6xh2
|
RNA binding protein-RNA |
X-ray (1.71 Å) |
Chavali SS, Mali SM, Jenkins JL, Fasan R, Wedekind
JE |
(2020) "Co-crystal
structures of HIV TAR RNA bound to lab-evolved proteins
show key roles for arginine relevant to the design of
cyclic peptide TAR inhibitors."
J.Biol.Chem., 295,
16470-16486. doi: 10.1074/jbc.RA120.015444.
|
Co-crystal structure of hiv-1 tar RNA in complex with
lab-evolved rrm 6.6 . SNAP output
|
|
6xh3
|
RNA binding protein-RNA |
X-ray (2.353 Å) |
Chavali SS, Mali SM, Jenkins JL, Fasan R, Wedekind
JE |
(2020) "Co-crystal
structures of HIV TAR RNA bound to lab-evolved proteins
show key roles for arginine relevant to the design of
cyclic peptide TAR inhibitors."
J.Biol.Chem., 295,
16470-16486. doi: 10.1074/jbc.RA120.015444.
|
Co-crystal structure of hiv-1 tar RNA in complex with
lab-evolved rrm tbp6.3 . SNAP output
|
|
6xhv
|
ribosome |
X-ray (2.4 Å) |
Svetlov MS, Syroegin EA, Aleksandrova EV, Atkinson
GC, Gregory ST, Mankin AS, Polikanov YS |
(2021) "Structure
of Erm-modified 70S ribosome reveals the mechanism of
macrolide resistance." Nat.Chem.Biol.,
17, 412-420. doi: 10.1038/s41589-020-00715-0.
|
Crystal structure of the a2058-dimethylated thermus
thermophilus 70s ribosome in complex with mrna,
aminoacylated a- and p-site trnas, and deacylated
e-site trna at 2.40a resolution . SNAP output
|
|
6xhw
|
ribosome |
X-ray (2.5 Å) |
Svetlov MS, Syroegin EA, Aleksandrova EV, Atkinson
GC, Gregory ST, Mankin AS, Polikanov YS |
(2021) "Structure
of Erm-modified 70S ribosome reveals the mechanism of
macrolide resistance." Nat.Chem.Biol.,
17, 412-420. doi: 10.1038/s41589-020-00715-0.
|
Crystal structure of the a2058-unmethylated thermus
thermophilus 70s ribosome in complex with mrna,
aminoacylated a- and p-site trnas, and deacylated
e-site trna at 2.50a resolution . SNAP output
|
|
6xhx
|
ribosome |
X-ray (2.55 Å) |
Svetlov MS, Syroegin EA, Aleksandrova EV, Atkinson
GC, Gregory ST, Mankin AS, Polikanov YS |
(2021) "Structure
of Erm-modified 70S ribosome reveals the mechanism of
macrolide resistance." Nat.Chem.Biol.,
17, 412-420. doi: 10.1038/s41589-020-00715-0.
|
Crystal structure of the a2058-unmethylated thermus
thermophilus 70s ribosome in complex with erythromycin
and protein y (yfia) at 2.55a resolution . SNAP output
|
|
6xhy
|
ribosome |
X-ray (2.6 Å) |
Svetlov MS, Syroegin EA, Aleksandrova EV, Atkinson
GC, Gregory ST, Mankin AS, Polikanov YS |
(2021) "Structure
of Erm-modified 70S ribosome reveals the mechanism of
macrolide resistance." Nat.Chem.Biol.,
17, 412-420. doi: 10.1038/s41589-020-00715-0.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with telithromycin, mrna,
aminoacylated a- and p-site trnas, and deacylated
e-site trna at 2.60a resolution . SNAP output
|
|
6xiq
|
ribosome |
cryo-EM (4.2 Å) |
Zhou Y, Kastritis PL, Dougherty SE, Bouvette J, Hsu
AL, Burbaum L, Mosalaganti S, Pfeffer S, Hagen WJH,
Forster F, Borgnia MJ, Vogel C, Beck M, Bartesaghi A,
Silva GM |
(2020) "Structural
impact of K63 ubiquitin on yeast translocating
ribosomes under oxidative stress."
Proc.Natl.Acad.Sci.USA, 117,
22157-22166. doi: 10.1073/pnas.2005301117.
|
cryo-EM structure of k63r ubiquitin mutant ribosome
under oxidative stress . SNAP output
|
|
6xir
|
ribosome |
cryo-EM (3.2 Å) |
Zhou Y, Kastritis PL, Dougherty SE, Bouvette J, Hsu
AL, Burbaum L, Mosalaganti S, Pfeffer S, Hagen WJH,
Forster F, Borgnia MJ, Vogel C, Beck M, Bartesaghi A,
Silva GM |
(2020) "Structural
impact of K63 ubiquitin on yeast translocating
ribosomes under oxidative stress."
Proc.Natl.Acad.Sci.USA, 117,
22157-22166. doi: 10.1073/pnas.2005301117.
|
cryo-EM structure of k63 ubiquitinated yeast
translocating ribosome under oxidative stress .
SNAP output
|
|
6xjq
|
RNA-immune system |
X-ray (1.708 Å) |
Krochmal D, Shao Y, Li NS, DasGupta S, Shelke SA,
Koirala D, Piccirilli JA |
(2022) "Structural
basis for substrate binding and catalysis by a
self-alkylating ribozyme." Nat.Chem.Biol.,
18, 376-384. doi: 10.1038/s41589-021-00950-z.
|
Crystal structure of a self-alkylating ribozyme -
alkylated form with biotinylated epoxide substrate .
SNAP output
|
|
6xjw
|
RNA-immune system |
X-ray (1.918 Å) |
Krochmal D, Shao Y, Li NS, DasGupta S, Shelke SA,
Koirala D, Piccirilli JA |
(2022) "Structural
basis for substrate binding and catalysis by a
self-alkylating ribozyme." Nat.Chem.Biol.,
18, 376-384. doi: 10.1038/s41589-021-00950-z.
|
Crystal structure of a self-alkylating ribozyme -
alkylated form without biotin moiety . SNAP output
|
|
6xjy
|
RNA-immune system |
X-ray (2.156 Å) |
Krochmal D, Shao Y, Li NS, DasGupta S, Shelke SA,
Koirala D, Piccirilli JA |
(2022) "Structural
basis for substrate binding and catalysis by a
self-alkylating ribozyme." Nat.Chem.Biol.,
18, 376-384. doi: 10.1038/s41589-021-00950-z.
|
Crystal structure of a self-alkylating ribozyme - short
time incubation with the epoxide substrate . SNAP output
|
|
6xjz
|
RNA-immune system |
X-ray (2.488 Å) |
Krochmal D, Shao Y, Li NS, DasGupta S, Shelke SA,
Koirala D, Piccirilli JA |
(2022) "Structural
basis for substrate binding and catalysis by a
self-alkylating ribozyme." Nat.Chem.Biol.,
18, 376-384. doi: 10.1038/s41589-021-00950-z.
|
Crystal structure of a self-alkylating ribozyme - apo
form . SNAP output
|
|
6xki
|
translation-RNA-inhibitor |
X-ray (2.87 Å) |
Naineni SK, Liang J, Hull K, Cencic R, Zhu M,
Northcote P, Teesdale-Spittle P, Romo D, Nagar B,
Pelletier J |
(2021) "Functional
mimicry revealed by the crystal structure of an
eIF4A:RNA complex bound to the interfacial inhibitor,
desmethyl pateamine A." Cell Chem Biol,
28, 825. doi: 10.1016/j.chembiol.2020.12.006.
|
Crystal structure of eif4a-i in complex with RNA bound
to des-mepatea, a pateamine a analog . SNAP output
|
|
6xl1
|
DNA binding protein-RNA |
X-ray (1.95 Å) |
Rostol JT, Xie W, Kuryavyi V, Maguin P, Kao K, Froom
R, Patel DJ, Marraffini LA |
(2021) "The
Card1 nuclease provides defence during type III CRISPR
immunity." Nature, 590,
624-629. doi: 10.1038/s41586-021-03206-x.
|
Crystal structure of ca4-activated card1(d294n) .
SNAP output
|
|
6xmf
|
hydrolase-RNA |
cryo-EM (3.1 Å) |
Li Z, Zhang H, Xiao R, Han R, Chang L |
(2021) "Cryo-EM
structure of the RNA-guided ribonuclease Cas12g."
Nat.Chem.Biol., 17, 387-393.
doi: 10.1038/s41589-020-00721-2.
|
cryo-EM structure of cas12g binary complex . SNAP output
|
|
6xmg
|
hydrolase-RNA |
cryo-EM (4.8 Å) |
Li Z, Zhang H, Xiao R, Han R, Chang L |
(2021) "Cryo-EM
structure of the RNA-guided ribonuclease Cas12g."
Nat.Chem.Biol., 17, 387-393.
doi: 10.1038/s41589-020-00721-2.
|
cryo-EM structure of cas12g ternary complex . SNAP output
|
|
6xn3
|
RNA binding protein-RNA |
cryo-EM (3.0 Å) |
Sridhara S, Rai J, Whyms C, Goswami H, He H, Woodside
W, Terns MP, Li H |
(2022) "Structural
and biochemical characterization of in vivo assembled
Lactococcus lactis CRISPR-Csm complex." Commun
Biol, 5, 279. doi: 10.1038/s42003-022-03187-1.
|
Structure of the lactococcus lactis csm ctr_4:3
crispr-cas complex . SNAP output
|
|
6xn4
|
RNA binding protein-RNA |
cryo-EM (3.35 Å) |
Sridhara S, Rai J, Whyms C, Goswami H, He H, Woodside
W, Terns MP, Li H |
(2022) "Structural
and biochemical characterization of in vivo assembled
Lactococcus lactis CRISPR-Csm complex." Commun
Biol, 5, 279. doi: 10.1038/s42003-022-03187-1.
|
Structure of the lactococcus lactis csm ctr_3:2
crispr-cas complex . SNAP output
|
|
6xn5
|
RNA binding protein-RNA |
cryo-EM (2.97 Å) |
Sridhara S, Rai J, Whyms C, Goswami H, He H, Woodside
W, Terns MP, Li H |
(2022) "Structural
and biochemical characterization of in vivo assembled
Lactococcus lactis CRISPR-Csm complex." Commun
Biol, 5, 279. doi: 10.1038/s42003-022-03187-1.
|
Structure of the lactococcus lactis csm apo- crispr-cas
complex . SNAP
output
|
|
6xn7
|
RNA binding protein-RNA |
cryo-EM (3.47 Å) |
Sridhara S, Rai J, Whyms C, Goswami H, He H, Woodside
W, Terns MP, Li H |
(2022) "Structural
and biochemical characterization of in vivo assembled
Lactococcus lactis CRISPR-Csm complex." Commun
Biol, 5, 279. doi: 10.1038/s42003-022-03187-1.
|
Structure of the lactococcus lactis csm ntr crispr-cas
complex . SNAP
output
|
|
6xqb
|
viral protein, transferase-hydrolase |
cryo-EM (3.4 Å) |
Liu B, Shi W, Yang Y |
"Structure of SARS-CoV-2 RdRp/RNA complex at 3.4
Angstroms resolution." |
Sars-cov-2 rdrp-RNA complex . SNAP output
|
|
6xqd
|
ribosome |
X-ray (2.8 Å) |
Batool Z, Lomakin IB, Polikanov YS, Bunick CG |
(2020) "Sarecycline
interferes with tRNA accommodation and tethers mRNA to
the 70S ribosome." Proc.Natl.Acad.Sci.USA,
117, 20530-20537. doi: 10.1073/pnas.2008671117.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with sarecycline, uuc-mrna, and
deacylated p-site trna at 2.80a resolution . SNAP output
|
|
6xqe
|
ribosome |
X-ray (3.0 Å) |
Batool Z, Lomakin IB, Polikanov YS, Bunick CG |
(2020) "Sarecycline
interferes with tRNA accommodation and tethers mRNA to
the 70S ribosome." Proc.Natl.Acad.Sci.USA,
117, 20530-20537. doi: 10.1073/pnas.2008671117.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with sarecycline, uaa-mrna, and
deacylated p-site trna at 3.00a resolution . SNAP output
|
|
6xyw
|
ribosome |
cryo-EM (3.86 Å) |
Waltz F, Soufari H, Bochler A, Giege P, Hashem Y |
(2020) "Cryo-EM
structure of the RNA-rich plant mitochondrial
ribosome." Nat.Plants, 6,
377-383. doi: 10.1038/s41477-020-0631-5.
|
Structure of the plant mitochondrial ribosome .
SNAP output
|
|
6xz7
|
ribosome |
cryo-EM (2.1 Å) |
Pichkur EB, Paleskava A, Tereshchenkov AG, Kasatsky
P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA,
Osterman IA, Sergiev PV, Polikanov YS, Myasnikov AG,
Konevega AL |
(2020) "Insights
into the improved macrolide inhibitory activity from
the high-resolution cryo-EM structure of dirithromycin
bound to theE. coli70S ribosome." Rna,
26, 715-723. doi: 10.1261/rna.073817.119.
|
E. coli 50s ribosomal subunit in complex with
dirithromycin, fmet-phe-trna(phe) and deacylated
trna(imet). . SNAP
output
|
|
6xza
|
ribosome |
cryo-EM (2.66 Å) |
Pichkur EB, Paleskava A, Tereshchenkov AG, Kasatsky
P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA,
Osterman IA, Sergiev PV, Polikanov YS, Myasnikov AG,
Konevega AL |
(2020) "Insights
into the improved macrolide inhibitory activity from
the high-resolution cryo-EM structure of dirithromycin
bound to the E. coli 70S ribosome." Rna,
26, 715-723. doi: 10.1261/rna.073817.119.
|
E. coli 70s ribosome in complex with dirithromycin, and
deacylated trna(imet) (focused classification). .
SNAP output
|
|
6xzb
|
ribosome |
cryo-EM (2.54 Å) |
Pichkur EB, Paleskava A, Tereshchenkov AG, Kasatsky
P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA,
Osterman IA, Sergiev PV, Polikanov YS, Myasnikov AG,
Konevega AL |
(2020) "Insights
into the improved macrolide inhibitory activity from
the high-resolution cryo-EM structure of dirithromycin
bound to the E. coli 70S ribosome." Rna,
26, 715-723. doi: 10.1261/rna.073817.119.
|
E. coli 70s ribosome in complex with dirithromycin,
fmet-phe-trna(phe) and deacylated trna(imet) (focused
classification). . SNAP
output
|
|
6xzd
|
viral protein |
cryo-EM (3.4 Å) |
Carrique L, Fan H, Walker AP, Keown JR, Sharps J,
Staller E, Barclay WS, Fodor E, Grimes JM |
(2020) "Host
ANP32A mediates the assembly of the influenza virus
replicase." Nature, 587,
638-643. doi: 10.1038/s41586-020-2927-z.
|
Influenza c virus polymerase complex without chicken
anp32a - subclass 2 . SNAP output
|
|
6xzg
|
viral protein |
cryo-EM (3.8 Å) |
Carrique L, Fan H, Walker AP, Keown JR, Sharps J,
Staller E, Barclay WS, Fodor E, Grimes JM |
(2020) "Host
ANP32A mediates the assembly of the influenza virus
replicase." Nature, 587,
638-643. doi: 10.1038/s41586-020-2927-z.
|
Influenza c virus polymerase in complex with chicken
anp32a - subclass 3 . SNAP output
|
|
6xzp
|
viral protein |
cryo-EM (3.3 Å) |
Carrique L, Fan H, Walker AP, Keown JR, Sharps J,
Staller E, Barclay WS, Fodor E, Grimes JM |
(2020) "Host
ANP32A mediates the assembly of the influenza virus
replicase." Nature, 587,
638-643. doi: 10.1038/s41586-020-2927-z.
|
Influenza c virus polymerase in complex with chicken
anp32a - subclass 4 . SNAP output
|
|
6xzq
|
viral protein |
cryo-EM (3.6 Å) |
Carrique L, Fan H, Walker AP, Keown JR, Sharps J,
Staller E, Barclay WS, Fodor E, Grimes JM |
(2020) "Host
ANP32A mediates the assembly of the influenza virus
replicase." Nature, 587,
638-643. doi: 10.1038/s41586-020-2927-z.
|
Influenza c virus polymerase in complex with human
anp32a - subclass 1 . SNAP output
|
|
6xzr
|
viral protein |
cryo-EM (3.3 Å) |
Carrique L, Fan H, Walker AP, Keown JR, Sharps J,
Staller E, Barclay WS, Fodor E, Grimes JM |
(2020) "Host
ANP32A mediates the assembly of the influenza virus
replicase." Nature, 587,
638-643. doi: 10.1038/s41586-020-2927-z.
|
Influenza c virus polymerase in complex with chicken
anp32a - subclass 1 . SNAP output
|
|
6y0c
|
viral protein |
cryo-EM (3.2 Å) |
Carrique L, Fan H, Walker AP, Keown JR, Sharps J,
Staller E, Barclay WS, Fodor E, Grimes JM |
(2020) "Host
ANP32A mediates the assembly of the influenza virus
replicase." Nature, 587,
638-643. doi: 10.1038/s41586-020-2927-z.
|
Influenza c virus polymerase in complex with human
anp32a - subclass 2 . SNAP output
|
|
6y0g
|
ribosome |
cryo-EM (3.2 Å) |
Bhaskar V, Graff-Meyer A, Schenk AD, Cavadini S, von
Loeffelholz O, Natchiar SK, Artus-Revel CG, Hotz HR,
Bretones G, Klaholz BP, Chao JA |
(2020) "Dynamics
of uS19 C-Terminal Tail during the Translation
Elongation Cycle in Human Ribosomes." Cell
Rep, 31, 107473. doi: 10.1016/j.celrep.2020.03.037.
|
Structure of human ribosome in classical-pre state .
SNAP output
|
|
6y2l
|
ribosome |
cryo-EM (3.0 Å) |
Bhaskar V, Graff-Meyer A, Schenk AD, Cavadini S, von
Loeffelholz O, Natchiar SK, Artus-Revel CG, Hotz HR,
Bretones G, Klaholz BP, Chao JA |
(2020) "Dynamics
of uS19 C-Terminal Tail during the Translation
Elongation Cycle in Human Ribosomes." Cell
Rep, 31, 107473. doi: 10.1016/j.celrep.2020.03.037.
|
Structure of human ribosome in post state . SNAP output
|
|
6y4b
|
RNA binding protein |
X-ray (5.0 Å) |
Bourgeois G, Seguin J, Babin M, Gondry M, Mechulam Y,
Schmitt E |
(2020) "Structural
basis of the interaction between cyclodipeptide
synthases and aminoacylated tRNA substrates."
Rna, 26, 1589-1602. doi:
10.1261/rna.075184.120.
|
Structure of cyclodipeptide synthase from candidatus
glomeribacter gigasporarum bound to phe-trnaphe .
SNAP output
|
|
6y50
|
splicing |
cryo-EM (4.1 Å) |
Zhang Z, Will CL, Bertram K, Dybkov O, Hartmuth K,
Agafonov DE, Hofele R, Urlaub H, Kastner B, Luhrmann R,
Stark H |
(2020) "Molecular
architecture of the human 17S U2 snRNP."
Nature, 583, 310-313. doi:
10.1038/s41586-020-2344-3.
|
5'domain of human 17s u2 snrnp . SNAP output
|
|
6y53
|
splicing |
cryo-EM (7.1 Å) |
Zhang Z, Will CL, Bertram K, Dybkov O, Hartmuth K,
Agafonov DE, Hofele R, Urlaub H, Kastner B, Luhrmann R,
Stark H |
(2020) "Molecular
architecture of the human 17S U2 snRNP."
Nature, 583, 310-313. doi:
10.1038/s41586-020-2344-3.
|
Human 17s u2 snrnp low resolution part . SNAP output
|
|
6y57
|
ribosome |
cryo-EM (3.5 Å) |
Bhaskar V, Graff-Meyer A, Schenk AD, Cavadini S, von
Loeffelholz O, Natchiar SK, Artus-Revel CG, Hotz HR,
Bretones G, Klaholz BP, Chao JA |
(2020) "Dynamics
of uS19 C-Terminal Tail during the Translation
Elongation Cycle in Human Ribosomes." Cell
Rep, 31, 107473. doi: 10.1016/j.celrep.2020.03.037.
|
Structure of human ribosome in hybrid-pre state .
SNAP output
|
|
6y5q
|
splicing |
cryo-EM (7.1 Å) |
Zhang Z, Will CL, Bertram K, Dybkov O, Hartmuth K,
Agafonov DE, Hofele R, Urlaub H, Kastner B, Luhrmann R,
Stark H |
(2020) "Molecular
architecture of the human 17S U2 snRNP."
Nature, 583, 310-313. doi:
10.1038/s41586-020-2344-3.
|
Human 17s u2 snrnp . SNAP output
|
|
6y69
|
ribosome |
cryo-EM (2.86 Å) |
Osterman IA, Wieland M, Maviza TP, Lashkevich KA,
Lukianov DA, Komarova ES, Zakalyukina YV, Buschauer R,
Shiriaev DI, Leyn SA, Zlamal JE, Biryukov MV, Skvortsov
DA, Tashlitsky VN, Polshakov VI, Cheng J, Polikanov YS,
Bogdanov AA, Osterman AL, Dmitriev SE, Beckmann R,
Dontsova OA, Wilson DN, Sergiev PV |
(2020) "Tetracenomycin
X inhibits translation by binding within the ribosomal
exit tunnel." Nat.Chem.Biol.,
16, 1071-1077. doi: 10.1038/s41589-020-0578-x.
|
cryo-EM structure of an escherichia coli 70s ribosome
in complex with antibiotic tetracenomycinx . SNAP output
|
|
6y7c
|
ribosome |
cryo-EM (3.8 Å) |
Shayan R, Rinaldi D, Larburu N, Plassart L, Balor S,
Bouyssie D, Lebaron S, Marcoux J, Gleizes PE,
Plisson-Chastang C |
(2020) "Good
Vibrations: Structural Remodeling of Maturing Yeast
Pre-40S Ribosomal Particles Followed by Cryo-Electron
Microscopy." Molecules,
25. doi: 10.3390/molecules25051125.
|
Early cytoplasmic yeast pre-40s particle (purified with
tsr1 as bait) . SNAP
output
|
|
6yal
|
translation |
cryo-EM (3.0 Å) |
Simonetti A, Guca E, Bochler A, Kuhn L, Hashem Y |
(2020) "Structural
Insights into the Mammalian Late-Stage Initiation
Complexes." Cell Rep, 31,
107497. doi: 10.1016/j.celrep.2020.03.061.
|
Mammalian 48s late-stage initiation complex with
beta-globin mrna . SNAP
output
|
|
6yam
|
translation |
cryo-EM (3.6 Å) |
Simonetti A, Guca E, Bochler A, Kuhn L, Hashem Y |
(2020) "Structural
Insights into the Mammalian Late-Stage Initiation
Complexes." Cell Rep, 31,
107497. doi: 10.1016/j.celrep.2020.03.061.
|
Mammalian 48s late-stage translation initiation complex
(ls48s+eif3 ic) with beta-globin mrna . SNAP output
|
|
6yan
|
translation |
cryo-EM (3.48 Å) |
Simonetti A, Guca E, Bochler A, Kuhn L, Hashem Y |
(2020) "Structural
Insights into the Mammalian Late-Stage Initiation
Complexes." Cell Rep, 31,
107497. doi: 10.1016/j.celrep.2020.03.061.
|
Mammalian 48s late-stage translation initiation complex
with histone 4 mrna . SNAP output
|
|
6ybs
|
translation |
cryo-EM (3.1 Å) |
Brito Querido J, Sokabe M, Kraatz S, Gordiyenko Y,
Skehel JM, Fraser CS, Ramakrishnan V |
(2020) "Structure
of a human 48Stranslational initiation complex."
Science, 369, 1220-1227. doi:
10.1126/science.aba4904.
|
Structure of a human 48s translational initiation
complex - head . SNAP
output
|
|
6ybv
|
translation |
cryo-EM (3.8 Å) |
Brito Querido J, Sokabe M, Kraatz S, Gordiyenko Y,
Skehel JM, Fraser CS, Ramakrishnan V |
(2020) "Structure
of a human 48Stranslational initiation complex."
Science, 369, 1220-1227. doi:
10.1126/science.aba4904.
|
Structure of a human 48s translational initiation
complex - eif2-tc . SNAP
output
|
|
6ydp
|
translation |
cryo-EM (3.0 Å) |
Kummer E, Ban N |
(2020) "Structural
insights into mammalian mitochondrial translation
elongation catalyzed by mtEFG1." Embo J.,
39, e104820. doi: 10.15252/embj.2020104820.
|
55s mammalian mitochondrial ribosome with mtefg1 and p
site fmet-trnamet (post) . SNAP output
|
|
6ydw
|
translation |
cryo-EM (4.2 Å) |
Kummer E, Ban N |
(2020) "Structural
insights into mammalian mitochondrial translation
elongation catalyzed by mtEFG1." Embo J.,
39, e104820. doi: 10.15252/embj.2020104820.
|
55s mammalian mitochondrial ribosome with mtefg1 and
two trnamet (ti-post) . SNAP output
|
|
6yef
|
ribosome |
cryo-EM (3.2 Å) |
Golubev A, Fatkhullin B, Khusainov I, Jenner L,
Gabdulkhakov A, Validov S, Yusupova G, Yusupov M, Usachev
K |
(2020) "Cryo-EM
structure of the ribosome functional complex of the
human pathogen Staphylococcus aureus at 3.2 angstrom
resolution." Febs Lett.,
594, 3551-3567. doi: 10.1002/1873-3468.13915.
|
70s initiation complex with assigned rrna modifications
from staphylococcus aureus . SNAP output
|
|
6yft
|
virus like particle |
X-ray (3.5 Å) |
Rumnieks J, Lieknina I, Kalnins G, Sisovs M, Akopjana
I, Bogans J, Tars K |
(2020) "Three-dimensional
structure of 22 uncultured ssRNA bacteriophages:
Flexibility of the coat protein fold and variations in
particle shapes." Sci Adv,
6. doi: 10.1126/sciadv.abc0023.
|
Virus-like particle of wenzhou levi-like virus 1 .
SNAP output
|
|
6yhs
|
ribosome |
cryo-EM (2.7 Å) |
Nicholson D, Edwards TA, O'Neill AJ, Ranson NA |
(2020) "Structure
of the 70S Ribosome from the Human Pathogen
Acinetobacter baumannii in Complex with Clinically
Relevant Antibiotics." Structure,
28, 1087-1100.e3. doi: 10.1016/j.str.2020.08.004.
|
Acinetobacter baumannii ribosome-amikacin complex - 50s
subunit . SNAP
output
|
|
6ylg
|
ribosome |
cryo-EM (3.0 Å) |
Kater L, Mitterer V, Thoms M, Cheng J, Berninghausen
O, Beckmann R, Hurt E |
(2020) "Construction
of the Central Protuberance and L1 Stalk during 60S
Subunit Biogenesis." Mol.Cell,
79, 615-628.e5. doi: 10.1016/j.molcel.2020.06.032.
|
Rix1-rea1 pre-60s particle - 60s core, body 1 (rigid
body refinement) . SNAP
output
|
|
6ylh
|
ribosome |
cryo-EM (3.1 Å) |
Kater L, Mitterer V, Thoms M, Cheng J, Berninghausen
O, Beckmann R, Hurt E |
(2020) "Construction
of the Central Protuberance and L1 Stalk during 60S
Subunit Biogenesis." Mol.Cell,
79, 615-628.e5. doi: 10.1016/j.molcel.2020.06.032.
|
Rix1-rea1 pre-60s particle - full composite structure .
SNAP output
|
|
6ylx
|
ribosome |
cryo-EM (3.9 Å) |
Kater L, Mitterer V, Thoms M, Cheng J, Berninghausen
O, Beckmann R, Hurt E |
(2020) "Construction
of the Central Protuberance and L1 Stalk during 60S
Subunit Biogenesis." Mol.Cell,
79, 615-628.e5. doi: 10.1016/j.molcel.2020.06.032.
|
Pre-60s state ne1 (tap-flag-nop53) . SNAP output
|
|
6yly
|
ribosome |
cryo-EM (3.8 Å) |
Kater L, Mitterer V, Thoms M, Cheng J, Berninghausen
O, Beckmann R, Hurt E |
(2020) "Construction
of the Central Protuberance and L1 Stalk during 60S
Subunit Biogenesis." Mol.Cell,
79, 615-628.e5. doi: 10.1016/j.molcel.2020.06.032.
|
Pre-60s state ne2 (tap-flag-nop53) . SNAP output
|
|
6ypu
|
ribosome |
cryo-EM (2.9 Å) |
Nicholson D, Edwards TA, O'Neill AJ, Ranson NA |
(2020) "Structure
of the 70S Ribosome from the Human Pathogen
Acinetobacter baumannii in Complex with Clinically
Relevant Antibiotics." Structure,
28, 1087-1100.e3. doi: 10.1016/j.str.2020.08.004.
|
Acinetobacter baumannii ribosome-amikacin complex - 30s
subunit body . SNAP
output
|
|
6yrq
|
viral protein |
X-ray (1.902 Å) |
Serris A, Stass R, Bignon EA, Muena NA, Manuguerra
JC, Jangra RK, Li S, Chandran K, Tischler ND, Huiskonen
JT, Rey FA, Guardado-Calvo P |
(2020) "The
Hantavirus Surface Glycoprotein Lattice and Its Fusion
Control Mechanism." Cell,
183, 442. doi: 10.1016/j.cell.2020.08.023.
|
Crystal structure of the tetramerization domain of the
glycoprotein gn (andes virus) at ph 4.6 . SNAP output
|
|
6ys3
|
ribosome |
cryo-EM (2.58 Å) |
Schulte L, Reitz J, Mao J, Sreeramulu S, Kudlinzki D,
Hodirnau VV, Meier-Credo J, Saxena K, Buhr F, Langer J,
Blackledge M, Glaubitz C, Frangakis A, Schwalbe H |
(2020) "Cryo-EM structure of the 50S ribosomal
subunit at 2.58 Angstroms with modeled GBC SecM peptide."
Nat Commun. |
cryo-EM structure of the 50s ribosomal subunit at 2.58
angstroms with modeled gbc secm peptide . SNAP output
|
|
6ys5
|
ribosome |
cryo-EM (3.0 Å) |
Nicholson D, Edwards TA, O'Neill AJ, Ranson NA |
(2020) "Structure
of the 70S Ribosome from the Human Pathogen
Acinetobacter baumannii in Complex with Clinically
Relevant Antibiotics." Structure,
28, 1087-1100.e3. doi: 10.1016/j.str.2020.08.004.
|
Acinetobacter baumannii ribosome-amikacin complex - 30s
subunit head . SNAP
output
|
|
6ysi
|
ribosome |
cryo-EM (2.5 Å) |
Nicholson D, Edwards TA, O'Neill AJ, Ranson NA |
(2020) "Structure
of the 70S Ribosome from the Human Pathogen
Acinetobacter baumannii in Complex with Clinically
Relevant Antibiotics." Structure,
28, 1087-1100.e3. doi: 10.1016/j.str.2020.08.004.
|
Acinetobacter baumannii ribosome-tigecycline complex -
50s subunit . SNAP
output
|
|
6ysr
|
ribosome |
cryo-EM (3.1 Å) |
Chan KH, Petrychenko V, Mueller C, Maracci C,
Holtkamp W, Wilson DN, Fischer N, Rodnina MV |
(2020) "Mechanism
of ribosome rescue by alternative ribosome-rescue
factor B." Nat Commun,
11, 4106. doi: 10.1038/s41467-020-17853-7.
|
Structure of the p+9 stalled ribosome complex .
SNAP output
|
|
6yss
|
ribosome |
cryo-EM (2.6 Å) |
Chan KH, Petrychenko V, Mueller C, Maracci C,
Holtkamp W, Wilson DN, Fischer N, Rodnina MV |
(2020) "Mechanism
of ribosome rescue by alternative ribosome-rescue
factor B." Nat Commun,
11, 4106. doi: 10.1038/s41467-020-17853-7.
|
Structure of the p+9 arfb-ribosome complex in the
post-hydrolysis state . SNAP output
|
|
6yst
|
ribosome |
cryo-EM (3.2 Å) |
Chan KH, Petrychenko V, Mueller C, Maracci C,
Holtkamp W, Wilson DN, Fischer N, Rodnina MV |
(2020) "Mechanism
of ribosome rescue by alternative ribosome-rescue
factor B." Nat Commun,
11, 4106. doi: 10.1038/s41467-020-17853-7.
|
Structure of the p+9 arfb-ribosome complex with p-e
hybrid trna in the post-hydrolysis state . SNAP output
|
|
6ysu
|
ribosome |
cryo-EM (3.7 Å) |
Chan KH, Petrychenko V, Mueller C, Maracci C,
Holtkamp W, Wilson DN, Fischer N, Rodnina MV |
(2020) "Mechanism
of ribosome rescue by alternative ribosome-rescue
factor B." Nat Commun,
11, 4106. doi: 10.1038/s41467-020-17853-7.
|
Structure of the p+0 arfb-ribosome complex in the
post-hydrolysis state . SNAP output
|
|
6yt9
|
ribosome |
cryo-EM (2.7 Å) |
Nicholson D, Edwards TA, O'Neill AJ, Ranson NA |
(2020) "Structure
of the 70S Ribosome from the Human Pathogen
Acinetobacter baumannii in Complex with Clinically
Relevant Antibiotics." Structure,
28, 1087-1100.e3. doi: 10.1016/j.str.2020.08.004.
|
Acinetobacter baumannii ribosome-tigecycline complex -
30s subunit body . SNAP
output
|
|
6ytf
|
ribosome |
cryo-EM (3.0 Å) |
Nicholson D, Edwards TA, O'Neill AJ, Ranson NA |
(2020) "Structure
of the 70S Ribosome from the Human Pathogen
Acinetobacter baumannii in Complex with Clinically
Relevant Antibiotics." Structure,
28, 1087-1100.e3. doi: 10.1016/j.str.2020.08.004.
|
Acinetobacter baumannii ribosome-tigecycline complex -
30s subunit head . SNAP
output
|
|
6yud
|
RNA binding protein |
X-ray (1.84 Å) |
Athukoralage JS, McQuarrie S, Gruschow S, Graham S,
Gloster TM, White MF |
(2020) "Tetramerisation
of the CRISPR ring nuclease Crn3/Csx3 facilitates
cyclic oligoadenylate cleavage." Elife,
9. doi: 10.7554/eLife.57627.
|
Structure of csx3-crn3 from archaeoglobus fulgidus in
complex with cyclic tetra-adenylate (ca4) . SNAP output
|
|
6yw5
|
translation |
cryo-EM (2.85 Å) |
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM,
Amunts A |
(2020) "Analysis
of translating mitoribosome reveals functional
characteristics of translation in mitochondria of
fungi." Nat Commun, 11,
5187. doi: 10.1038/s41467-020-18830-w.
|
The structure of the small subunit of the mitoribosome
from neurospora crassa . SNAP output
|
|
6ywe
|
translation |
cryo-EM (2.99 Å) |
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM,
Amunts A |
(2020) "Analysis
of translating mitoribosome reveals functional
characteristics of translation in mitochondria of
fungi." Nat Commun, 11,
5187. doi: 10.1038/s41467-020-18830-w.
|
The structure of the mitoribosome from neurospora
crassa in the p-e trna bound state . SNAP output
|
|
6ywo
|
RNA binding protein |
X-ray (1.9 Å) |
Malik D, Kobylecki K, Krawczyk P, Poznanski J,
Jakielaszek A, Napiorkowska A, Dziembowski A, Tomecki R,
Nowotny M |
(2020) "Structure
and mechanism of CutA, RNA nucleotidyl transferase with
an unusual preference for cytosine." Nucleic
Acids Res., 48, 9387-9405. doi:
10.1093/nar/gkaa647.
|
Cuta in complex with a3 RNA . SNAP output
|
|
6yws
|
translation |
cryo-EM (2.74 Å) |
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM,
Amunts A |
(2020) "Analysis
of translating mitoribosome reveals functional
characteristics of translation in mitochondria of
fungi." Nat Commun, 11,
5187. doi: 10.1038/s41467-020-18830-w.
|
The structure of the large subunit of the mitoribosome
from neurospora crassa . SNAP output
|
|
6ywv
|
translation |
cryo-EM (3.03 Å) |
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM,
Amunts A |
(2020) "Analysis
of translating mitoribosome reveals functional
characteristics of translation in mitochondria of
fungi." Nat Commun, 11,
5187. doi: 10.1038/s41467-020-18830-w.
|
The structure of the atp25 bound assembly intermediate
of the mitoribosome from neurospora crassa . SNAP output
|
|
6ywx
|
translation |
cryo-EM (3.1 Å) |
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM,
Amunts A |
(2020) "Analysis
of translating mitoribosome reveals functional
characteristics of translation in mitochondria of
fungi." Nat Commun, 11,
5187. doi: 10.1038/s41467-020-18830-w.
|
The structure of the mitoribosome from neurospora
crassa with trna bound to the e-site . SNAP output
|
|
6ywy
|
translation |
cryo-EM (3.05 Å) |
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM,
Amunts A |
(2020) "Analysis
of translating mitoribosome reveals functional
characteristics of translation in mitochondria of
fungi." Nat Commun, 11,
5187. doi: 10.1038/s41467-020-18830-w.
|
The structure of the mitoribosome from neurospora
crassa with bound trna at the p-site . SNAP output
|
|
6yxx
|
ribosome |
cryo-EM (3.9 Å) |
Jaskolowski M, Ramrath DJF, Bieri P, Niemann M,
Mattei S, Calderaro S, Leibundgut M, Horn EK, Boehringer
D, Schneider A, Ban N |
(2020) "Structural
Insights into the Mechanism of Mitoribosomal Large
Subunit Biogenesis." Mol.Cell,
79, 629-644.e4. doi: 10.1016/j.molcel.2020.06.030.
|
State a of the trypanosoma brucei mitoribosomal large
subunit assembly intermediate . SNAP output
|
|
6yxy
|
ribosome |
cryo-EM (3.1 Å) |
Jaskolowski M, Ramrath DJF, Bieri P, Niemann M,
Mattei S, Calderaro S, Leibundgut M, Horn EK, Boehringer
D, Schneider A, Ban N |
(2020) "Structural
Insights into the Mechanism of Mitoribosomal Large
Subunit Biogenesis." Mol.Cell,
79, 629-644.e4. doi: 10.1016/j.molcel.2020.06.030.
|
State b of the trypanosoma brucei mitoribosomal large
subunit assembly intermediate . SNAP output
|
|
6yym
|
RNA binding protein |
X-ray (2.63 Å) |
Andric V, Nevers A, Hazra D, Auxilien S, Menant A,
Graille M, Palancade B, Rougemaille M |
(2021) "A
scaffold lncRNA shapes the mitosis to meiosis
switch." Nat Commun, 12,
770. doi: 10.1038/s41467-021-21032-7.
|
Structure of s. pombe mei2 rrm3 domain bound to RNA .
SNAP output
|
|
6yyt
|
viral protein |
cryo-EM (2.9 Å) |
Hillen HS, Kokic G, Farnung L, Dienemann C, Tegunov
D, Cramer P |
(2020) "Structure
of replicating SARS-CoV-2 polymerase."
Nature, 584, 154-156. doi:
10.1038/s41586-020-2368-8.
|
Structure of replicating sars-cov-2 polymerase .
SNAP output
|
|
6z1p
|
ribosome |
cryo-EM (3.7 Å) |
Tobiasson V, Amunts A |
(2020) "Ciliate
mitoribosome illuminates evolutionary steps of
mitochondrial translation." Elife,
9. doi: 10.7554/eLife.59264.
|
Structure of the mitochondrial ribosome from
tetrahymena thermophila . SNAP output
|
|
6z6b
|
viral protein |
X-ray (3.961 Å) |
Arragain B, Effantin G, Gerlach P, Reguera J, Schoehn
G, Cusack S, Malet H |
(2020) "Pre-initiation
and elongation structures of full-length La Crosse
virus polymerase reveal functionally important
conformational changes." Nat Commun,
11, 3590. doi: 10.1038/s41467-020-17349-4.
|
Structure of full-length la crosse virus l protein
(polymerase) . SNAP
output
|
|
6z6g
|
replication |
cryo-EM (3.06 Å) |
Arragain B, Effantin G, Gerlach P, Reguera J, Schoehn
G, Cusack S, Malet H |
(2020) "Pre-initiation
and elongation structures of full-length La Crosse
virus polymerase reveal functionally important
conformational changes." Nat Commun,
11, 3590. doi: 10.1038/s41467-020-17349-4.
|
cryo-EM structure of la crosse virus polymerase at
pre-initiation stage . SNAP output
|
|
6z6j
|
ribosome |
cryo-EM (3.4 Å) |
Wells JN, Buschauer R, Mackens-Kiani T, Best K,
Kratzat H, Berninghausen O, Becker T, Gilbert W, Cheng J,
Beckmann R |
(2020) "Structure
and function of yeast Lso2 and human CCDC124 bound to
hibernating ribosomes." Plos Biol.,
18, e3000780. doi: 10.1371/journal.pbio.3000780.
|
cryo-EM structure of yeast lso2 bound to 80s ribosomes
under native condition . SNAP output
|
|
6z6k
|
ribosome |
cryo-EM (3.4 Å) |
Wells JN, Buschauer R, Mackens-Kiani T, Best K,
Kratzat H, Berninghausen O, Becker T, Gilbert W, Cheng J,
Beckmann R |
(2020) "Structure
and function of yeast Lso2 and human CCDC124 bound to
hibernating ribosomes." Plos Biol.,
18, e3000780. doi: 10.1371/journal.pbio.3000780.
|
cryo-EM structure of yeast reconstituted lso2 bound to
80s ribosomes . SNAP
output
|
|
6z8k
|
replication |
cryo-EM (3.02 Å) |
Arragain B, Effantin G, Gerlach P, Reguera J, Schoehn
G, Cusack S, Malet H |
(2020) "Pre-initiation
and elongation structures of full-length La Crosse
virus polymerase reveal functionally important
conformational changes." Nat Commun,
11, 3590. doi: 10.1038/s41467-020-17349-4.
|
La crosse virus polymerase at elongation mimicking
stage . SNAP output
|
|
6zce
|
ribosome |
cryo-EM (5.3 Å) |
Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak
M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog
F, Fromont-Racine M, Becker T, Beckmann R |
(2021) "A
structural inventory of native ribosomal ABCE1-43S
pre-initiation complexes." Embo J.,
40, e105179. doi: 10.15252/embj.2020105179.
|
Structure of a yeast abce1-bound 43s pre-initiation
complex . SNAP
output
|
|
6zdp
|
replication |
X-ray (2.85 Å) |
Zhai LT, Rety S, Chen WF, Song ZY, Auguin D, Sun B,
Dou SX, Xi XG |
(2021) "Crystal
structures of N-terminally truncated telomerase reverse
transcriptase from fungi‡." Nucleic Acids
Res., 49, 4768-4781. doi:
10.1093/nar/gkab261.
|
Structure of telomerase from candida tropicalis in
complexe with twj fragment of telomeric RNA . SNAP output
|
|
6zdq
|
replication |
X-ray (2.98 Å) |
Zhai LT, Rety S, Chen WF, Song ZY, Auguin D, Sun B,
Dou SX, Xi XG |
(2021) "Crystal
structures of N-terminally truncated telomerase reverse
transcriptase from fungi‡." Nucleic Acids
Res., 49, 4768-4781. doi:
10.1093/nar/gkab261.
|
Structure of telomerase from candida albicans in
complexe with twj fragment of telomeric RNA . SNAP output
|
|
6zdu
|
replication |
X-ray (3.45 Å) |
Zhai LT, Rety S, Chen WF, Song ZY, Auguin D, Sun B,
Dou SX, Xi XG |
(2021) "Crystal
structures of N-terminally truncated telomerase reverse
transcriptase from fungi‡." Nucleic Acids
Res., 49, 4768-4781. doi:
10.1093/nar/gkab261.
|
Structure of telomerase from candida albicans in
complexe with twj fragment of telomeric RNA . SNAP output
|
|
6zlc
|
viral protein |
X-ray (2.3 Å) |
Wacquiez A, Coste F, Kut E, Gaudon V, Trapp S,
Castaing B, Marc D |
(2020) "Structure
and Sequence Determinants Governing the Interactions of
RNAs with Influenza A Virus Non-Structural Protein
NS1." Viruses, 12. doi:
10.3390/v12090947.
|
Non-specific dsrna recognition by wildtype h7n1
RNA-binding domain . SNAP output
|
|
6zlw
|
viral protein |
cryo-EM (2.6 Å) |
Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T,
Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T,
Cheng J, Straub JH, Sturzel CM, Frohlich T, Berninghausen
O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R |
(2020) "Structural
basis for translational shutdown and immune evasion by
the Nsp1 protein of SARS-CoV-2." Science,
369, 1249-1255. doi: 10.1126/science.abc8665.
|
Sars-cov-2 nsp1 bound to the human 40s ribosomal
subunit . SNAP
output
|
|
6zm2
|
hydrolase |
X-ray (2.1 Å) |
Hamann F, Zimmerningkat LC, Becker RA, Garbers TB,
Neumann P, Hub JS, Ficner R |
(2021) "The
structure of Prp2 bound to RNA and ADP-BeF 3 - reveals
structural features important for RNA unwinding by
DEAH-box ATPases." Acta Crystallogr D Struct
Biol, 77, 496-509. doi: 10.1107/S2059798321001194.
|
Crystal structure of the deah-box atpase prp2 in
complex with adp-bef3 and ssrna . SNAP output
|
|
6zm5
|
ribosome |
cryo-EM (2.89 Å) |
Itoh Y, Andrell J, Choi A, Richter U, Maiti P, Best
RB, Barrientos A, Battersby BJ, Amunts A |
(2021) "Mechanism
of membrane-tethered mitochondrial protein
synthesis." Science, 371,
846-849. doi: 10.1126/science.abe0763.
|
Human mitochondrial ribosome in complex with oxa1l,
mrna, a-a trna, p-p trna and nascent polypeptide .
SNAP output
|
|
6zm6
|
ribosome |
cryo-EM (2.59 Å) |
Itoh Y, Andrell J, Choi A, Richter U, Maiti P, Best
RB, Barrientos A, Battersby BJ, Amunts A |
(2021) "Mechanism
of membrane-tethered mitochondrial protein
synthesis." Science, 371,
846-849. doi: 10.1126/science.abe0763.
|
Human mitochondrial ribosome in complex with mrna, a-a
trna and p-p trna . SNAP
output
|
|
6zmt
|
viral protein |
cryo-EM (3.0 Å) |
Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T,
Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T,
Cheng J, Straub JH, Sturzel CM, Frohlich T, Berninghausen
O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R |
(2020) "Structural
basis for translational shutdown and immune evasion by
the Nsp1 protein of SARS-CoV-2." Science,
369, 1249-1255. doi: 10.1126/science.abc8665.
|
Sars-cov-2 nsp1 bound to a pre-40s-like ribosome
complex . SNAP
output
|
|
6zn5
|
viral protein |
cryo-EM (3.2 Å) |
Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T,
Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T,
Cheng J, Straub JH, Sturzel CM, Frohlich T, Berninghausen
O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R |
(2020) "Structural
basis for translational shutdown and immune evasion by
the Nsp1 protein of SARS-CoV-2." Science,
369, 1249-1255. doi: 10.1126/science.abc8665.
|
Sars-cov-2 nsp1 bound to a pre-40s-like ribosome
complex - state 2 . SNAP
output
|
|
6zoj
|
translation |
cryo-EM (2.8 Å) |
Schubert K, Karousis ED, Jomaa A, Scaiola A,
Echeverria B, Gurzeler LA, Leibundgut M, Thiel V,
Muhlemann O, Ban N |
(2020) "SARS-CoV-2
Nsp1 binds the ribosomal mRNA channel to inhibit
translation." Nat.Struct.Mol.Biol.,
27, 959-966. doi: 10.1038/s41594-020-0511-8.
|
Sars-cov-2-nsp1-40s complex, composite map . SNAP output
|
|
6zok
|
translation |
cryo-EM (2.8 Å) |
Schubert K, Karousis ED, Jomaa A, Scaiola A,
Echeverria B, Gurzeler LA, Leibundgut M, Thiel V,
Muhlemann O, Ban N |
(2020) "SARS-CoV-2
Nsp1 binds the ribosomal mRNA channel to inhibit
translation." Nat.Struct.Mol.Biol.,
27, 959-966. doi: 10.1038/s41594-020-0511-8.
|
Sars-cov-2-nsp1-40s complex, focused on body . SNAP output
|
|
6zol
|
translation |
cryo-EM (2.8 Å) |
Schubert K, Karousis ED, Jomaa A, Scaiola A,
Echeverria B, Gurzeler LA, Leibundgut M, Thiel V,
Muhlemann O, Ban N |
(2020) "SARS-CoV-2
Nsp1 binds the ribosomal mRNA channel to inhibit
translation." Nat.Struct.Mol.Biol.,
27, 959-966. doi: 10.1038/s41594-020-0511-8.
|
Sars-cov-2-nsp1-40s complex, focused on head . SNAP output
|
|
6zon
|
viral protein |
cryo-EM (3.0 Å) |
Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T,
Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T,
Cheng J, Straub JH, Sturzel CM, Frohlich T, Berninghausen
O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R |
(2020) "Structural
basis for translational shutdown and immune evasion by
the Nsp1 protein of SARS-CoV-2." Science,
369, 1249-1255. doi: 10.1126/science.abc8665.
|
Sars-cov-2 nsp1 bound to a human 43s preinitiation
ribosome complex - state 1 . SNAP output
|
|
6zot
|
RNA binding protein |
X-ray (2.7 Å) |
Li Y, Bedi RK, Moroz-Omori EV, Caflisch A |
(2020) "Structural
and Dynamic Insights into Redundant Function of YTHDF
Proteins." J.Chem.Inf.Model.,
60, 5932-5935. doi: 10.1021/acs.jcim.0c01029.
|
Crystal structure of ythdf3 yth domain in complex with
m6a RNA . SNAP
output
|
|
6zp4
|
viral protein |
cryo-EM (2.9 Å) |
Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T,
Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T,
Cheng J, Straub JH, Sturzel CM, Frohlich T, Berninghausen
O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R |
(2020) "Structural
basis for translational shutdown and immune evasion by
the Nsp1 protein of SARS-CoV-2." Science,
369, 1249-1255. doi: 10.1126/science.abc8665.
|
Sars-cov-2 nsp1 bound to a human 43s preinitiation
ribosome complex - state 2 . SNAP output
|
|
6zqa
|
ribosome |
cryo-EM (4.4 Å) |
Cheng J, Lau B, La Venuta G, Ameismeier M,
Berninghausen O, Hurt E, Beckmann R |
(2020) "90 S
pre-ribosome transformation into the primordial 40 S
subunit." Science, 369,
1470-1476. doi: 10.1126/science.abb4119.
|
cryo-EM structure of the 90s pre-ribosome from
saccharomyces cerevisiae, state a (poly-ala) . SNAP output
|
|
6zqb
|
ribosome |
cryo-EM (3.9 Å) |
Cheng J, Lau B, La Venuta G, Ameismeier M,
Berninghausen O, Hurt E, Beckmann R |
(2020) "90 S
pre-ribosome transformation into the primordial 40 S
subunit." Science, 369,
1470-1476. doi: 10.1126/science.abb4119.
|
cryo-EM structure of the 90s pre-ribosome from
saccharomyces cerevisiae, state b2 . SNAP output
|
|
6zqc
|
ribosome |
cryo-EM (3.8 Å) |
Cheng J, Lau B, La Venuta G, Ameismeier M,
Berninghausen O, Hurt E, Beckmann R |
(2020) "90 S
pre-ribosome transformation into the primordial 40 S
subunit." Science, 369,
1470-1476. doi: 10.1126/science.abb4119.
|
cryo-EM structure of the 90s pre-ribosome from
saccharomyces cerevisiae, state pre-a1 . SNAP output
|
|
6zqd
|
ribosome |
cryo-EM (3.8 Å) |
Cheng J, Lau B, La Venuta G, Ameismeier M,
Berninghausen O, Hurt E, Beckmann R |
(2020) "90 S
pre-ribosome transformation into the primordial 40 S
subunit." Science, 369,
1470-1476. doi: 10.1126/science.abb4119.
|
cryo-EM structure of the 90s pre-ribosome from
saccharomyces cerevisiae, state post-a1 . SNAP output
|
|
6zqe
|
ribosome |
cryo-EM (7.1 Å) |
Cheng J, Lau B, La Venuta G, Ameismeier M,
Berninghausen O, Hurt E, Beckmann R |
(2020) "90 S
pre-ribosome transformation into the primordial 40 S
subunit." Science, 369,
1470-1476. doi: 10.1126/science.abb4119.
|
cryo-EM structure of the 90s pre-ribosome from
saccharomyces cerevisiae, state dis-a (poly-ala) .
SNAP output
|
|
6zqf
|
ribosome |
cryo-EM (4.9 Å) |
Cheng J, Lau B, La Venuta G, Ameismeier M,
Berninghausen O, Hurt E, Beckmann R |
(2020) "90 S
pre-ribosome transformation into the primordial 40 S
subunit." Science, 369,
1470-1476. doi: 10.1126/science.abb4119.
|
cryo-EM structure of the 90s pre-ribosome from
saccharomyces cerevisiae, state dis-b (poly-ala) .
SNAP output
|
|
6zqg
|
ribosome |
cryo-EM (3.5 Å) |
Cheng J, Lau B, La Venuta G, Ameismeier M,
Berninghausen O, Hurt E, Beckmann R |
(2020) "90 S
pre-ribosome transformation into the primordial 40 S
subunit." Science, 369,
1470-1476. doi: 10.1126/science.abb4119.
|
cryo-EM structure of the 90s pre-ribosome from
saccharomyces cerevisiae, state dis-c . SNAP output
|
|
6zs9
|
translation |
cryo-EM (4.0 Å) |
Aibara S, Singh V, Modelska A, Amunts A |
(2020) "Structural
basis of mitochondrial translation."
Elife, 9. doi: 10.7554/eLife.58362.
|
Human mitochondrial ribosome in complex with ribosome
recycling factor . SNAP
output
|
|
6zsa
|
translation |
cryo-EM (4.0 Å) |
Aibara S, Singh V, Modelska A, Amunts A |
(2020) "Structural
basis of mitochondrial translation."
Elife, 9. doi: 10.7554/eLife.58362.
|
Human mitochondrial ribosome bound to mrna, a-site trna
and p-site trna . SNAP
output
|
|
6zsb
|
translation |
cryo-EM (4.5 Å) |
Aibara S, Singh V, Modelska A, Amunts A |
(2020) "Structural
basis of mitochondrial translation."
Elife, 9. doi: 10.7554/eLife.58362.
|
Human mitochondrial ribosome in complex with mrna and
p-site trna . SNAP
output
|
|
6zsc
|
translation |
cryo-EM (3.5 Å) |
Aibara S, Singh V, Modelska A, Amunts A |
(2020) "Structural
basis of mitochondrial translation."
Elife, 9. doi: 10.7554/eLife.58362.
|
Human mitochondrial ribosome in complex with e-site
trna . SNAP output
|
|
6zsd
|
translation |
cryo-EM (3.7 Å) |
Aibara S, Singh V, Modelska A, Amunts A |
(2020) "Structural
basis of mitochondrial translation."
Elife, 9. doi: 10.7554/eLife.58362.
|
Human mitochondrial ribosome in complex with mrna,
p-site trna and e-site trna . SNAP output
|
|
6zse
|
translation |
cryo-EM (5.0 Å) |
Aibara S, Singh V, Modelska A, Amunts A |
(2020) "Structural
basis of mitochondrial translation."
Elife, 9. doi: 10.7554/eLife.58362.
|
Human mitochondrial ribosome in complex with mrna,
a-p-trna and p-e-trna . SNAP output
|
|
6zsg
|
translation |
cryo-EM (4.0 Å) |
Aibara S, Singh V, Modelska A, Amunts A |
(2020) "Structural
basis of mitochondrial translation."
Elife, 9. doi: 10.7554/eLife.58362.
|
Human mitochondrial ribosome in complex with mrna,
a-site trna, p-site trna and e-site trna . SNAP output
|
|
6zu5
|
ribosome |
cryo-EM (2.9 Å) |
Ehrenbolger K, Jespersen N, Sharma H, Sokolova YY,
Tokarev YS, Vossbrinck CR, Barandun J |
(2020) "Differences
in structure and hibernation mechanism highlight
diversification of the microsporidian ribosome."
Plos Biol., 18, e3000958.
doi: 10.1371/journal.pbio.3000958.
|
Structure of the paranosema locustae ribosome in
complex with lso2 . SNAP
output
|
|
6zu9
|
ribosome |
cryo-EM (6.2 Å) |
Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak
M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog
F, Fromont-Racine M, Becker T, Beckmann R |
(2021) "A
structural inventory of native ribosomal ABCE1-43S
pre-initiation complexes." Embo J.,
40, e105179. doi: 10.15252/embj.2020105179.
|
Structure of a yeast abce1-bound 48s initiation complex
. SNAP output
|
|
6zuo
|
ribosome |
cryo-EM (3.1 Å) |
Plassart L, Shayan R, Montellese C, Rinaldi D,
Larburu N, Pichereaux C, Froment C, Lebaron S, O'Donohue
MF, Kutay U, Marcoux J, Gleizes PE, Plisson-Chastang
C |
(2021) "The
final step of 40S ribosomal subunit maturation is
controlled by a dual key lock." Elife,
10. doi: 10.7554/eLife.61254.
|
Human rio1(kd)-stha late pre-40s particle, structural
state a (pre 18s rrna cleavage) . SNAP output
|
|
6zv6
|
ribosome |
cryo-EM (2.9 Å) |
Plassart L, Shayan R, Montellese C, Rinaldi D,
Larburu N, Pichereaux C, Froment C, Lebaron S, O'Donohue
MF, Kutay U, Marcoux J, Gleizes PE, Plisson-Chastang
C |
(2021) "The
final step of 40S ribosomal subunit maturation is
controlled by a dual key lock." Elife,
10. doi: 10.7554/eLife.61254.
|
Human rio1(kd)-stha late pre-40s particle, structural
state b (post 18s rrna cleavage) . SNAP output
|
|
6zvi
|
ribosome |
cryo-EM (3.0 Å) |
Sinha NK, Ordureau A, Best K, Saba JA, Zinshteyn B,
Sundaramoorthy E, Fulzele A, Garshott DM, Denk T, Thoms
M, Paulo JA, Harper W, Bennett EJ, Beckmann R, Green
R |
(2020) "EDF1
coordinates cellular responses to ribosome
collisions." Elife, 9.
doi: 10.7554/eLife.58828.
|
Mbf1-ribosome complex . SNAP output
|
|
6zvj
|
ribosome |
cryo-EM (3.8 Å) |
Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak
M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog
F, Fromont-Racine M, Becker T, Beckmann R |
(2021) "A
structural inventory of native ribosomal ABCE1-43S
pre-initiation complexes." Embo J.,
40, e105179. doi: 10.15252/embj.2020105179.
|
Structure of a human abce1-bound 43s pre-initiation
complex - state ii . SNAP output
|
|
6zvk
|
translation |
cryo-EM (3.49 Å) |
Abaeva IS, Vicens Q, Bochler A, Soufari H, Simonetti
A, Pestova TV, Hashem Y, Hellen CUT |
(2020) "The
Halastavi arva Virus Intergenic Region IRES Promotes
Translation by the Simplest Possible Initiation
Mechanism." Cell Rep, 33,
108476. doi: 10.1016/j.celrep.2020.108476.
|
The halastavi arva virus (halv) intergenic region ires
promotes translation by the simplest possible
initiation mechanism . SNAP output
|
|
6zww
|
RNA binding protein |
X-ray (3.16 Å) |
Grass LM, Wollenhaupt J, Barthel T, Parfentev I,
Urlaub H, Loll B, Klauck E, Antelmann H, Wahl MC |
(2021) "Large-scale
ratcheting in a bacterial DEAH/RHA-type RNA helicase
that modulates antibiotics susceptibility."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2100370118.
|
Crystal structure of e. coli RNA helicase hrpa in
complex with RNA . SNAP
output
|
|
6zxd
|
ribosome |
cryo-EM (3.2 Å) |
Ameismeier M, Zemp I, van den Heuvel J, Thoms M,
Berninghausen O, Kutay U, Beckmann R |
(2020) "Structural
basis for the final steps of human 40S ribosome
maturation." Nature, 587,
683-687. doi: 10.1038/s41586-020-2929-x.
|
cryo-EM structure of a late human pre-40s ribosomal
subunit - state f1 . SNAP output
|
|
6zxe
|
ribosome |
cryo-EM (3.0 Å) |
Ameismeier M, Zemp I, van den Heuvel J, Thoms M,
Berninghausen O, Kutay U, Beckmann R |
(2020) "Structural
basis for the final steps of human 40S ribosome
maturation." Nature, 587,
683-687. doi: 10.1038/s41586-020-2929-x.
|
cryo-EM structure of a late human pre-40s ribosomal
subunit - state f2 . SNAP output
|
|
6zxf
|
ribosome |
cryo-EM (3.7 Å) |
Ameismeier M, Zemp I, van den Heuvel J, Thoms M,
Berninghausen O, Kutay U, Beckmann R |
(2020) "Structural
basis for the final steps of human 40S ribosome
maturation." Nature, 587,
683-687. doi: 10.1038/s41586-020-2929-x.
|
cryo-EM structure of a late human pre-40s ribosomal
subunit - state g . SNAP
output
|
|
6zxg
|
ribosome |
cryo-EM (2.6 Å) |
Ameismeier M, Zemp I, van den Heuvel J, Thoms M,
Berninghausen O, Kutay U, Beckmann R |
(2020) "Structural
basis for the final steps of human 40S ribosome
maturation." Nature, 587,
683-687. doi: 10.1038/s41586-020-2929-x.
|
cryo-EM structure of a late human pre-40s ribosomal
subunit - state h1 . SNAP output
|
|
6zxh
|
ribosome |
cryo-EM (2.7 Å) |
Ameismeier M, Zemp I, van den Heuvel J, Thoms M,
Berninghausen O, Kutay U, Beckmann R |
(2020) "Structural
basis for the final steps of human 40S ribosome
maturation." Nature, 587,
683-687. doi: 10.1038/s41586-020-2929-x.
|
cryo-EM structure of a late human pre-40s ribosomal
subunit - state h2 . SNAP output
|
|
6zym
|
splicing |
cryo-EM (3.4 Å) |
Bertram K, El Ayoubi L, Dybkov O, Agafonov DE, Will
CL, Hartmuth K, Urlaub H, Kastner B, Stark H, Luhrmann
R |
(2020) "Structural
Insights into the Roles of Metazoan-Specific Splicing
Factors in the Human Step 1 Spliceosome."
Mol.Cell, 80, 127-139.e6.
doi: 10.1016/j.molcel.2020.09.012.
|
Human c complex spliceosome - high-resolution core .
SNAP output
|
|
7a01
|
ribosome |
cryo-EM (3.6 Å) |
Abaeva IS, Vicens Q, Bochler A, Soufari H, Simonetti
A, Pestova TV, Hashem Y, Hellen CUT |
(2020) "The
Halastavi arva Virus Intergenic Region IRES Promotes
Translation by the Simplest Possible Initiation
Mechanism." Cell Rep, 33,
108476. doi: 10.1016/j.celrep.2020.108476.
|
The halastavi arva virus intergenic region ires
promotes translation by the simplest possible
initiation mechanism . SNAP output
|
|
7a09
|
ribosome |
cryo-EM (3.5 Å) |
Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak
M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog
F, Fromont-Racine M, Becker T, Beckmann R |
(2021) "A
structural inventory of native ribosomal ABCE1-43S
pre-initiation complexes." Embo J.,
40, e105179. doi: 10.15252/embj.2020105179.
|
Structure of a human abce1-bound 43s pre-initiation
complex - state iii . SNAP output
|
|
7a0r
|
antibiotic |
X-ray (3.3 Å) |
Breiner-Goldstein E, Eyal Z, Matzov D, Halfon Y,
Cimicata G, Baum M, Rokney A, Ezernitchi AV, Lowell AN,
Schmidt JJ, Rozenberg H, Zimmerman E, Bashan A, Valinsky
L, Anzai Y, Sherman DH, Yonath A |
(2021) "Ribosome-binding
and anti-microbial studies of the mycinamicins,
16-membered macrolide antibiotics from Micromonospora
griseorubida." Nucleic Acids Res.,
49, 9560-9573. doi: 10.1093/nar/gkab684.
|
50s deinococcus radiodurans ribosome bounded with
mycinamicin i . SNAP
output
|
|
7a0s
|
antibiotic |
X-ray (3.22 Å) |
Breiner-Goldstein E, Eyal Z, Matzov D, Halfon Y,
Cimicata G, Baum M, Rokney A, Ezernitchi AV, Lowell AN,
Schmidt JJ, Rozenberg H, Zimmerman E, Bashan A, Valinsky
L, Anzai Y, Sherman DH, Yonath A |
(2021) "Ribosome-binding
and anti-microbial studies of the mycinamicins,
16-membered macrolide antibiotics from Micromonospora
griseorubida." Nucleic Acids Res.,
49, 9560-9573. doi: 10.1093/nar/gkab684.
|
50s deinococcus radiodurans ribosome bounded with
mycinamicin i . SNAP
output
|
|
7a18
|
antibiotic |
X-ray (3.4 Å) |
Breiner-Goldstein E, Eyal Z, Matzov D, Halfon Y,
Cimicata G, Baum M, Rokney A, Ezernitchi AV, Lowell AN,
Schmidt JJ, Rozenberg H, Zimmerman E, Bashan A, Valinsky
L, Anzai Y, Sherman DH, Yonath A |
(2021) "Ribosome-binding
and anti-microbial studies of the mycinamicins,
16-membered macrolide antibiotics from Micromonospora
griseorubida." Nucleic Acids Res.,
49, 9560-9573. doi: 10.1093/nar/gkab684.
|
50s deinococcus radiodurans ribosome bounded with
mycinamicin iv . SNAP
output
|
|
7a1g
|
ribosome |
cryo-EM (3.0 Å) |
Kratzat H, Mackens-Kiani T, Ameismeier M, Potocnjak
M, Cheng J, Dacheux E, Namane A, Berninghausen O, Herzog
F, Fromont-Racine M, Becker T, Beckmann R |
(2021) "A
structural inventory of native ribosomal ABCE1-43S
pre-initiation complexes." Embo J.,
40, e105179. doi: 10.15252/embj.2020105179.
|
Structure of a crosslinked yeast abce1-bound 43s
pre-initiation complex . SNAP output
|
|
7a5f
|
ribosome |
cryo-EM (4.4 Å) |
Desai N, Yang H, Chandrasekaran V, Kazi R, Minczuk M,
Ramakrishnan V |
(2020) "Elongational
stalling activates mitoribosome-associated quality
control." Science, 370,
1105-1110. doi: 10.1126/science.abc7782.
|
Structure of the stalled human mitoribosome with p- and
e-site mt-trnas . SNAP
output
|
|
7a5g
|
ribosome |
cryo-EM (4.33 Å) |
Desai N, Yang H, Chandrasekaran V, Kazi R, Minczuk M,
Ramakrishnan V |
(2020) "Elongational
stalling activates mitoribosome-associated quality
control." Science, 370,
1105-1110. doi: 10.1126/science.abc7782.
|
Structure of the elongating human mitoribosome bound to
mtef-tu.gmppcp and a-t mt-trna . SNAP output
|
|
7a5h
|
ribosome |
cryo-EM (3.3 Å) |
Desai N, Yang H, Chandrasekaran V, Kazi R, Minczuk M,
Ramakrishnan V |
(2020) "Elongational
stalling activates mitoribosome-associated quality
control." Science, 370,
1105-1110. doi: 10.1126/science.abc7782.
|
Structure of the split human mitoribosomal large
subunit with rescue factors mtrf-r and mtres1 .
SNAP output
|
|
7a5i
|
ribosome |
cryo-EM (3.7 Å) |
Desai N, Yang H, Chandrasekaran V, Kazi R, Minczuk M,
Ramakrishnan V |
(2020) "Elongational
stalling activates mitoribosome-associated quality
control." Science, 370,
1105-1110. doi: 10.1126/science.abc7782.
|
Structure of the human mitoribosome with a- p-and
e-site mt-trnas . SNAP
output
|
|
7a5j
|
ribosome |
cryo-EM (3.1 Å) |
Desai N, Yang H, Chandrasekaran V, Kazi R, Minczuk M,
Ramakrishnan V |
(2020) "Elongational
stalling activates mitoribosome-associated quality
control." Science, 370,
1105-1110. doi: 10.1126/science.abc7782.
|
Structure of the split human mitoribosomal large
subunit with p-and e-site mt-trnas . SNAP output
|
|
7a5k
|
ribosome |
cryo-EM (3.7 Å) |
Desai N, Yang H, Chandrasekaran V, Kazi R, Minczuk M,
Ramakrishnan V |
(2020) "Elongational
stalling activates mitoribosome-associated quality
control." Science, 370,
1105-1110. doi: 10.1126/science.abc7782.
|
Structure of the human mitoribosome in the post
translocation state bound to mtef-g1 . SNAP output
|
|
7a5p
|
splicing |
cryo-EM (5.0 Å) |
Bertram K, El Ayoubi L, Dybkov O, Agafonov DE, Will
CL, Hartmuth K, Urlaub H, Kastner B, Stark H, Luhrmann
R |
(2020) "Structural
Insights into the Roles of Metazoan-Specific Splicing
Factors in the Human Step 1 Spliceosome."
Mol.Cell, 80, 127-139.e6.
doi: 10.1016/j.molcel.2020.09.012.
|
Human c complex spliceosome - medium-resolution
periphery . SNAP
output
|
|
7a9w
|
RNA binding protein |
X-ray (2.55 Å) |
Hillen HS, Markov DA, Wojtas ID, Hofmann KB,
Lidschreiber M, Cowan AT, Jones JL, Temiakov D, Cramer P,
Anikin M |
(2021) "The
pentatricopeptide repeat protein Rmd9 recognizes the
dodecameric element in the 3'-UTRs of yeast
mitochondrial mRNAs."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2009329118.
|
Structure of yeast rmd9p in complex with 20nt target
RNA . SNAP output
|
|
7a9x
|
RNA binding protein |
X-ray (2.45 Å) |
Hillen HS, Markov DA, Wojtas ID, Hofmann KB,
Lidschreiber M, Cowan AT, Jones JL, Temiakov D, Cramer P,
Anikin M |
(2021) "The
pentatricopeptide repeat protein Rmd9 recognizes the
dodecameric element in the 3'-UTRs of yeast
mitochondrial mRNAs."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2009329118.
|
Structure of yeast rmd9p in complex with 16nt target
RNA . SNAP output
|
|
7aap
|
viral protein |
cryo-EM (2.5 Å) |
Naydenova K, Muir KW, Wu LF, Zhang Z, Coscia F, Peet
MJ, Castro-Hartmann P, Qian P, Sader K, Dent K, Kimanius
D, Sutherland JD, Lowe J, Barford D, Russo CJ |
(2021) "Structure
of the SARS-CoV-2 RNA-dependent RNA polymerase in the
presence of favipiravir-RTP."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2021946118.
|
Nsp7-nsp8-nsp12 sars-cov2 RNA-dependent RNA polymerase
in complex with template:primer dsrna and
favipiravir-rtp . SNAP
output
|
|
7aav
|
splicing |
cryo-EM (4.2 Å) |
Townsend C, Leelaram MN, Agafonov DE, Dybkov O, Will
CL, Bertram K, Urlaub H, Kastner B, Stark H, Luhrmann
R |
(2020) "Mechanism
of protein-guided folding of the active site U2/U6 RNA
during spliceosome activation." Science,
370. doi: 10.1126/science.abc3753.
|
Human pre-bact-2 spliceosome core structure . SNAP output
|
|
7abf
|
splicing |
cryo-EM (3.9 Å) |
Townsend C, Leelaram MN, Agafonov DE, Dybkov O, Will
CL, Bertram K, Urlaub H, Kastner B, Stark H, Luhrmann
R |
(2020) "Mechanism
of protein-guided folding of the active site U2/U6 RNA
during spliceosome activation." Science,
370. doi: 10.1126/science.abc3753.
|
Human pre-bact-1 spliceosome core structure . SNAP output
|
|
7abg
|
splicing |
cryo-EM (7.8 Å) |
Townsend C, Leelaram MN, Agafonov DE, Dybkov O, Will
CL, Bertram K, Urlaub H, Kastner B, Stark H, Luhrmann
R |
(2020) "Mechanism
of protein-guided folding of the active site U2/U6 RNA
during spliceosome activation." Science,
370. doi: 10.1126/science.abc3753.
|
Human pre-bact-1 spliceosome . SNAP output
|
|
7abh
|
splicing |
cryo-EM (4.5 Å) |
Townsend C, Leelaram MN, Agafonov DE, Dybkov O, Will
CL, Bertram K, Urlaub H, Kastner B, Stark H, Luhrmann
R |
(2020) "Mechanism
of protein-guided folding of the active site U2/U6 RNA
during spliceosome activation." Science,
370. doi: 10.1126/science.abc3753.
|
Human pre-bact-2 spliceosome (sf3b-u2 snrnp portion) .
SNAP output
|
|
7abi
|
splicing |
cryo-EM (8.0 Å) |
Townsend C, Leelaram MN, Agafonov DE, Dybkov O, Will
CL, Bertram K, Urlaub H, Kastner B, Stark H, Luhrmann
R |
(2020) "Mechanism
of protein-guided folding of the active site U2/U6 RNA
during spliceosome activation." Science,
370. doi: 10.1126/science.abc3753.
|
Human pre-bact-2 spliceosome . SNAP output
|
|
7abz
|
translation |
cryo-EM (3.21 Å) |
Guyomar C, D'Urso G, Chat S, Giudice E, Gillet R |
(2021) "Structures
of tmRNA and SmpB as they transit through the
ribosome." Nat Commun,
12, 4909. doi: 10.1038/s41467-021-24881-4.
|
Structure of pre-accomodated trans-translation complex
on e. coli stalled ribosome. . SNAP output
|
|
7ac7
|
translation |
cryo-EM (3.08 Å) |
Guyomar C, D'Urso G, Chat S, Giudice E, Gillet R |
(2021) "Structures
of tmRNA and SmpB as they transit through the
ribosome." Nat Commun,
12, 4909. doi: 10.1038/s41467-021-24881-4.
|
Structure of accomodated trans-translation complex on
e. coli stalled ribosome. . SNAP output
|
|
7acj
|
translation |
cryo-EM (3.2 Å) |
Guyomar C, D'Urso G, Chat S, Giudice E, Gillet R |
(2021) "Structures
of tmRNA and SmpB as they transit through the
ribosome." Nat Commun,
12, 4909. doi: 10.1038/s41467-021-24881-4.
|
Structure of translocated trans-translation complex on
e. coli stalled ribosome. . SNAP output
|
|
7acr
|
translation |
cryo-EM (3.44 Å) |
Guyomar C, D'Urso G, Chat S, Giudice E, Gillet R |
(2021) "Structures
of tmRNA and SmpB as they transit through the
ribosome." Nat Commun,
12, 4909. doi: 10.1038/s41467-021-24881-4.
|
Structure of post-translocated trans-translation
complex on e. coli stalled ribosome. . SNAP output
|
|
7acs
|
viral protein |
NMR |
Dinesh DC, Chalupska D, Silhan J, Koutna E, Nencka R,
Veverka V, Boura E |
(2020) "Structural
basis of RNA recognition by the SARS-CoV-2 nucleocapsid
phosphoprotein." Plos Pathog.,
16, e1009100. doi: 10.1371/journal.ppat.1009100.
|
The sars-cov-2 nucleocapsid phosphoprotein n-terminal
domain in complex with 7mer dsrna . SNAP output
|
|
7act
|
viral protein |
NMR |
Dinesh DC, Chalupska D, Silhan J, Koutna E, Nencka R,
Veverka V, Boura E |
(2020) "Structural
basis of RNA recognition by the SARS-CoV-2 nucleocapsid
phosphoprotein." Plos Pathog.,
16, e1009100. doi: 10.1371/journal.ppat.1009100.
|
The sars-cov-2 nucleocapsid phosphoprotein n-terminal
domain in complex with 10mer ssrna . SNAP output
|
|
7af3
|
ribosome |
cryo-EM (2.82 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
m (head domain) . SNAP
output
|
|
7af5
|
ribosome |
cryo-EM (2.96 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
i (head domain) . SNAP
output
|
|
7af8
|
ribosome |
cryo-EM (2.75 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
e (head domain) . SNAP
output
|
|
7afa
|
ribosome |
cryo-EM (2.95 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
f (head domain) . SNAP
output
|
|
7afd
|
ribosome |
cryo-EM (3.44 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
a (head domain) . SNAP
output
|
|
7afh
|
ribosome |
cryo-EM (3.59 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
c (head domain) . SNAP
output
|
|
7afi
|
ribosome |
cryo-EM (3.53 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
c (body domain) . SNAP
output
|
|
7afk
|
ribosome |
cryo-EM (4.9 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
d (head domain) . SNAP
output
|
|
7afl
|
ribosome |
cryo-EM (4.2 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
d (multibody refinement for body domain of 30s
ribosome) . SNAP
output
|
|
7afn
|
ribosome |
cryo-EM (3.86 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
b (head domain) . SNAP
output
|
|
7afo
|
ribosome |
cryo-EM (3.93 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
b (body domain) . SNAP
output
|
|
7aih
|
ribosome |
cryo-EM (3.6 Å) |
Soufari H, Waltz F, Parrot C, Durrieu-Gaillard S,
Bochler A, Kuhn L, Sissler M, Hashem Y |
(2020) "Structure
of the mature kinetoplastids mitoribosome and insights
into its large subunit biogenesis."
Proc.Natl.Acad.Sci.USA, 117,
29851-29861. doi: 10.1073/pnas.2011301117.
|
The large subunit of the kinetoplastid mitochondrial
ribosome . SNAP
output
|
|
7ajt
|
ribosome |
cryo-EM (4.6 Å) |
Lau B, Cheng J, Flemming D, La Venuta G,
Berninghausen O, Beckmann R, Hurt E |
(2021) "Structure
of the Maturing 90S Pre-ribosome in Association with
the RNA Exosome." Mol.Cell,
81, 293. doi: 10.1016/j.molcel.2020.11.009.
|
cryo-EM structure of the 90s-exosome super-complex
(state pre-a1-exosome) . SNAP output
|
|
7aju
|
ribosome |
cryo-EM (3.8 Å) |
Lau B, Cheng J, Flemming D, La Venuta G,
Berninghausen O, Beckmann R, Hurt E |
(2021) "Structure
of the Maturing 90S Pre-ribosome in Association with
the RNA Exosome." Mol.Cell,
81, 293. doi: 10.1016/j.molcel.2020.11.009.
|
cryo-EM structure of the 90s-exosome super-complex
(state post-a1-exosome) . SNAP output
|
|
7am2
|
ribosome |
cryo-EM (3.4 Å) |
Soufari H, Waltz F, Parrot C, Durrieu-Gaillard S,
Bochler A, Kuhn L, Sissler M, Hashem Y |
(2020) "Structure
of the mature kinetoplastids mitoribosome and insights
into its large subunit biogenesis."
Proc.Natl.Acad.Sci.USA, 117,
29851-29861. doi: 10.1073/pnas.2011301117.
|
Intermediate assembly of the large subunit from
leishmania major mitochondrial ribosome . SNAP output
|
|
7ane
|
ribosome |
cryo-EM (3.9 Å) |
Soufari H, Waltz F, Parrot C, Durrieu-Gaillard S,
Bochler A, Kuhn L, Sissler M, Hashem Y |
(2020) "Structure
of the mature kinetoplastids mitoribosome and insights
into its large subunit biogenesis."
Proc.Natl.Acad.Sci.USA, 117,
29851-29861. doi: 10.1073/pnas.2011301117.
|
Leishmania major mitochondrial ribosome . SNAP output
|
|
7aoi
|
ribosome |
cryo-EM (3.5 Å) |
Tobiasson V, Gahura O, Aibara S, Baradaran R, Zikova
A, Amunts A |
(2021) "Interconnected
assembly factors regulate the biogenesis of
mitoribosomal large subunit." Embo J.,
40, e106292. doi: 10.15252/embj.2020106292.
|
Trypanosoma brucei mitochondrial ribosome large subunit
assembly intermediate . SNAP output
|
|
7aor
|
ribosome |
cryo-EM (3.5 Å) |
Soufari H, Waltz F, Parrot C, Durrieu-Gaillard S,
Bochler A, Kuhn L, Sissler M, Hashem Y |
(2020) "Structure
of the mature kinetoplastids mitoribosome and insights
into its large subunit biogenesis."
Proc.Natl.Acad.Sci.USA, 117,
29851-29861. doi: 10.1073/pnas.2011301117.
|
Mt-ssu from trypanosoma cruzi in complex with mt-if-3.
. SNAP output
|
|
7aqc
|
ribosome |
cryo-EM (2.99 Å) |
Filbeck S, Cerullo F, Paternoga H, Tsaprailis G,
Joazeiro CAP, Pfeffer S |
(2021) "Mimicry
of Canonical Translation Elongation Underlies Alanine
Tail Synthesis in RQC." Mol.Cell,
81, 104. doi: 10.1016/j.molcel.2020.11.001.
|
Structure of the bacterial rqc complex (decoding state)
. SNAP output
|
|
7aqd
|
ribosome |
cryo-EM (3.1 Å) |
Filbeck S, Cerullo F, Paternoga H, Tsaprailis G,
Joazeiro CAP, Pfeffer S |
(2021) "Mimicry
of Canonical Translation Elongation Underlies Alanine
Tail Synthesis in RQC." Mol.Cell,
81, 104. doi: 10.1016/j.molcel.2020.11.001.
|
Structure of the bacterial rqc complex (translocating
state) . SNAP output
|
|
7as8
|
translation |
cryo-EM (2.9 Å) |
Crowe-McAuliffe C, Takada H, Murina V, Polte C,
Kasvandik S, Tenson T, Ignatova Z, Atkinson GC, Wilson
DN, Hauryliuk V |
(2021) "Structural
Basis for Bacterial Ribosome-Associated Quality Control
by RqcH and RqcP." Mol.Cell,
81, 115. doi: 10.1016/j.molcel.2020.11.002.
|
Bacillus subtilis ribosome quality control complex
state b. ribosomal 50s subunit with p-trna, rqch, and
rqcp-yabo . SNAP
output
|
|
7as9
|
translation |
cryo-EM (3.5 Å) |
Crowe-McAuliffe C, Takada H, Murina V, Polte C,
Kasvandik S, Tenson T, Ignatova Z, Atkinson GC, Wilson
DN, Hauryliuk V |
(2021) "Structural
Basis for Bacterial Ribosome-Associated Quality Control
by RqcH and RqcP." Mol.Cell,
81, 115. doi: 10.1016/j.molcel.2020.11.002.
|
Bacillus subtilis ribosome-associated quality control
complex state a. ribosomal 50s subunit with peptidyl
trna in the a-p position and rqch. . SNAP output
|
|
7asa
|
translation |
cryo-EM (3.5 Å) |
Crowe-McAuliffe C, Takada H, Murina V, Polte C,
Kasvandik S, Tenson T, Ignatova Z, Atkinson GC, Wilson
DN, Hauryliuk V |
(2021) "Structural
Basis for Bacterial Ribosome-Associated Quality Control
by RqcH and RqcP." Mol.Cell,
81, 115. doi: 10.1016/j.molcel.2020.11.002.
|
Bacillus subtilis ribosome-associated quality control
complex state b, multibody refinement focussed on rqch.
ribosomal 50s subunit with p-trna, rqch, and rqcp-yabo
. SNAP output
|
|
7ase
|
translation |
cryo-EM (3.33 Å) |
Bochler A, Querido JB, Prilepskaja T, Soufari H,
Simonetti A, Del Cistia ML, Kuhn L, Ribeiro AR, Valasek
LS, Hashem Y |
(2020) "Structural
Differences in Translation Initiation between
Pathogenic Trypanosomatids and Their Mammalian
Hosts." Cell Rep, 33,
108534. doi: 10.1016/j.celrep.2020.108534.
|
43s preinitiation complex from trypanosoma cruzi with
the kddx60 helicase . SNAP output
|
|
7asm
|
ribosome |
cryo-EM (2.48 Å) |
Cimicata G, Bashan A, Yonath A |
"Staphylococcus aureus 50S after 30 minutes
incubation a 37C." |
Staphylococcus aureus 50s after 30 minutes incubation
at 37c . SNAP output
|
|
7asn
|
ribosome |
cryo-EM (2.73 Å) |
Cimicata G, Bashan A, Yonath A |
"Staphylococcus aureus 50S after 30 minutes
incubation a 37C." |
Staphylococcus aureus 50s after 30 minutes incubation a
37c . SNAP output
|
|
7aso
|
ribosome |
cryo-EM (3.11 Å) |
Cimicata G, Bashan A, Yonath A |
"Staphylococcus aureus 70S after 30 minutes
incubation a 37C." |
Staphylococcus aureus 70s after 30 minutes incubation
at 37c . SNAP output
|
|
7asp
|
ribosome |
cryo-EM (2.86 Å) |
Cimicata G, Bashan A, Yonath A |
"Staphylococcus aureus 50S after 30 minutes
incubation a 37C." |
Staphylococcus aureus 70s after 50 minutes incubation
at 37c . SNAP output
|
|
7azo
|
ribosome |
X-ray (3.3 Å) |
Zhang J, Lair C, Roubert C, Amaning K, Barrio MB,
Benedetti Y, Cui Z, Xing Z, Li X, Franzblau SG, Baurin N,
Bordon-Pallier F, Cantalloube C, Sans S, Silve S, Blanc
I, Fraisse L, Rak A, Jenner LB, Yusupova G, Yusupov M,
Zhang J, Kaneko T, Yang TJ, Fotouhi N, Nuermberger E,
Tyagi S, Betoudji F, Upton A, Sacchettini JC, Lagrange
S |
(2023) "Discovery
of natural-product-derived sequanamycins as potent oral
anti-tuberculosis agents." Cell,
186, 1013-1025.e24. doi: 10.1016/j.cell.2023.01.043.
|
70s thermus thermophilus ribosome with bound antibiotic
lead seq-977 . SNAP
output
|
|
7azs
|
ribosome |
X-ray (3.1 Å) |
Zhang J, Lair C, Roubert C, Amaning K, Barrio MB,
Benedetti Y, Cui Z, Xing Z, Li X, Franzblau SG, Baurin N,
Bordon-Pallier F, Cantalloube C, Sans S, Silve S, Blanc
I, Fraisse L, Rak A, Jenner LB, Yusupova G, Yusupov M,
Zhang J, Kaneko T, Yang TJ, Fotouhi N, Nuermberger E,
Tyagi S, Betoudji F, Upton A, Sacchettini JC, Lagrange
S |
(2023) "Discovery
of natural-product-derived sequanamycins as potent oral
anti-tuberculosis agents." Cell,
186, 1013-1025.e24. doi: 10.1016/j.cell.2023.01.043.
|
70s thermus thermophilus ribosome with bound antibiotic
lead seq-569 . SNAP
output
|
|
7azy
|
ribosome |
cryo-EM (2.877 Å) |
Svetlov MS, Koller TO, Meydan S, Shankar V, Klepacki
D, Polacek N, Guydosh NR, Vazquez-Laslop N, Wilson DN,
Mankin AS |
(2021) "Context-specific
action of macrolide antibiotics on the eukaryotic
ribosome." Nat Commun,
12, 2803. doi: 10.1038/s41467-021-23068-1.
|
Context-specific inhibition of eukaryotic translation
by macrolide antibiotics . SNAP output
|
|
7b3b
|
viral protein |
cryo-EM (3.1 Å) |
Kokic G, Hillen HS, Tegunov D, Dienemann C, Seitz F,
Schmitzova J, Farnung L, Siewert A, Hobartner C, Cramer
P |
(2021) "Mechanism
of SARS-CoV-2 polymerase stalling by remdesivir."
Nat Commun, 12, 279. doi:
10.1038/s41467-020-20542-0.
|
Structure of elongating sars-cov-2 RNA-dependent RNA
polymerase with remdesivir at position -3 (structure 1)
. SNAP output
|
|
7b3c
|
viral protein |
cryo-EM (3.4 Å) |
Kokic G, Hillen HS, Tegunov D, Dienemann C, Seitz F,
Schmitzova J, Farnung L, Siewert A, Hobartner C, Cramer
P |
(2021) "Mechanism
of SARS-CoV-2 polymerase stalling by remdesivir."
Nat Commun, 12, 279. doi:
10.1038/s41467-020-20542-0.
|
Structure of elongating sars-cov-2 RNA-dependent RNA
polymerase with remdesivir at position -4 (structure 2)
. SNAP output
|
|
7b3d
|
viral protein |
cryo-EM (2.8 Å) |
Kokic G, Hillen HS, Tegunov D, Dienemann C, Seitz F,
Schmitzova J, Farnung L, Siewert A, Hobartner C, Cramer
P |
(2021) "Mechanism
of SARS-CoV-2 polymerase stalling by remdesivir."
Nat Commun, 12, 279. doi:
10.1038/s41467-020-20542-0.
|
Structure of elongating sars-cov-2 RNA-dependent RNA
polymerase with amp at position -4 (structure 3) .
SNAP output
|
|
7b5k
|
ribosome |
cryo-EM (2.9 Å) |
Albers S, Beckert B, Wilson ND, Ignatova Z |
(2021) "Harnessing evolutionarily flexibility in
tRNAs to maximize nonsense suppression activities."
Nat Commun. |
E. coli 70s containing suppressor trna in the a-site
stabilized by a negamycin analogue and p-site
trna-nascent chain. . SNAP output
|
|
7b7d
|
translation |
cryo-EM (3.3 Å) |
Ranjan N, Pochopien AA, Wu CC, Beckert B, Blanchet S,
Green R, Rodnina MV, Wilson DN |
"eEF3 promotes late stages of tRNA translocation
including E-tRNA release from the ribosome." |
Yeast 80s ribosome bound to eef3 and a-a- and p-p-trnas
. SNAP output
|
|
7b9v
|
splicing |
cryo-EM (2.8 Å) |
Wilkinson ME, Fica SM, Galej WP, Nagai K |
(2021) "Structural
basis for conformational equilibrium of the catalytic
spliceosome." Mol.Cell,
81, 1439. doi: 10.1016/j.molcel.2021.02.021.
|
Yeast c complex spliceosome at 2.8 angstrom resolution
with prp18-slu7 bound . SNAP output
|
|
7bah
|
immune system |
X-ray (1.89 Å) |
de Regt AK, Anand K, Ciupka K, Bender F, Gatterdam K,
Putschli B, Fussholler D, Hilbig D, Kirchhoff A, Hunkler
C, Wolter S, Grunewald A, Wallerath C, Schuberth-Wagner
C, Ludwig J, Paeschke K, Bartok E, Hagelueken G, Hartmann
G, Zillinger T, Geyer M, Schlee M |
(2023) "A
conserved isoleucine in the binding pocket of RIG-I
controls immune tolerance to mitochondrial RNA."
Nucleic Acids Res., 51,
11893-11910. doi: 10.1093/nar/gkad835.
|
Structure of rig-i ctd bound to oh-RNA . SNAP output
|
|
7bai
|
immune system |
X-ray (3.4 Å) |
de Regt AK, Anand K, Ciupka K, Bender F, Gatterdam K,
Putschli B, Fussholler D, Hilbig D, Kirchhoff A, Hunkler
C, Wolter S, Grunewald A, Wallerath C, Schuberth-Wagner
C, Ludwig J, Paeschke K, Bartok E, Hagelueken G, Hartmann
G, Zillinger T, Geyer M, Schlee M |
(2023) "A
conserved isoleucine in the binding pocket of RIG-I
controls immune tolerance to mitochondrial RNA."
Nucleic Acids Res., 51,
11893-11910. doi: 10.1093/nar/gkad835.
|
Structure of rig-i ctd (i875a) bound to p-RNA .
SNAP output
|
|
7bdv
|
DNA binding protein |
X-ray (2.02 Å) |
Zhu W, McQuarrie S, Gruschow S, McMahon SA, Graham S,
Gloster TM, White MF |
(2021) "The
CRISPR ancillary effector Can2 is a dual-specificity
nuclease potentiating type III CRISPR defence."
Nucleic Acids Res., 49,
2777-2789. doi: 10.1093/nar/gkab073.
|
Structure of can2 from sulfobacillus
thermosulfidooxidans in complex with cyclic
tetra-adenylate (ca4) . SNAP output
|
|
7bg6
|
virus |
cryo-EM (2.6 Å) |
Hrebik D, Fuzik T, Gondova M, Smerdova L, Adamopoulos
A, Sedo O, Zdrahal Z, Plevka P |
(2021) "ICAM-1
induced rearrangements of capsid and genome prime
rhinovirus 14 for activation and uncoating."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2024251118.
|
Hrv14 native particle solved by cryoem . SNAP output
|
|
7bgb
|
RNA binding protein |
cryo-EM (3.4 Å) |
Ghanim GE, Fountain AJ, van Roon AM, Rangan R, Das R,
Collins K, Nguyen THD |
(2021) "Structure
of human telomerase holoenzyme with bound telomeric
DNA." Nature, 593,
449-453. doi: 10.1038/s41586-021-03415-4.
|
The h-aca rnp lobe of human telomerase . SNAP output
|
|
7bgd
|
ribosome |
cryo-EM (3.2 Å) |
Belinite M, Khusainov I, Soufari H, Marzi S, Romby P,
Yusupov M, Hashem Y |
(2021) "Stabilization of Ribosomal RNA of the Small
Subunit by Spermidine in Staphylococcus aureus."
Front Mol Biosci, 8, 1022. |
Staphylococcus aureus 30s ribosomal subunit in presence
of spermidine (body only) . SNAP output
|
|
7bge
|
ribosome |
cryo-EM (3.6 Å) |
Belinite M, Khusainov I, Soufari H, Marzi S, Romby P,
Yusupov M, Hashem Y |
(2021) "Stabilization of Ribosomal RNA of the Small
Subunit by Spermidine in Staphylococcus aureus."
Front Mol Biosci, 8, 1022. |
Staphylococcus aureus 30s ribosomal subunit in presence
of spermidine (head only) . SNAP output
|
|
7bhp
|
ribosome |
cryo-EM (3.3 Å) |
Bhaskar V, Desogus J, Graff-Meyer A, Schenk AD,
Cavadini S, Chao JA |
(2021) "Dynamic
association of human Ebp1 with the ribosome."
Rna, 27, 411-419. doi:
10.1261/rna.077602.120.
|
cryo-EM structure of the human ebp1 - 80s ribosome .
SNAP output
|
|
7bkp
|
immune system |
cryo-EM (2.8 Å) |
Yu Q, Herrero Del Valle A, Singh R, Modis Y |
(2021) "MDA5
disease variant M854K prevents ATP-dependent structural
discrimination of viral and cellular RNA." Nat
Commun, 12, 6668. doi: 10.1038/s41467-021-27062-5.
|
Cryoem structure of disease related m854k mda5-dsrna
filament in complex with atp . SNAP output
|
|
7bkq
|
immune system |
cryo-EM (3.4 Å) |
Yu Q, Herrero Del Valle A, Singh R, Modis Y |
(2021) "MDA5
disease variant M854K prevents ATP-dependent structural
discrimination of viral and cellular RNA." Nat
Commun, 12, 6668. doi: 10.1038/s41467-021-27062-5.
|
Cryoem structure of mda5-dsrna filament in complex with
adp with 92-degree helical twist . SNAP output
|
|
7bl2
|
ribosome |
cryo-EM (3.7 Å) |
Nikolay R, Hilal T, Schmidt S, Qin B, Schwefel D,
Vieira-Vieira CH, Mielke T, Burger J, Loerke J, Amikura
K, Flugel T, Ueda T, Selbach M, Deuerling E, Spahn
CMT |
(2021) "Snapshots
of native pre-50S ribosomes reveal a biogenesis factor
network and evolutionary specialization."
Mol.Cell, 81, 1200-1215.e9.
doi: 10.1016/j.molcel.2021.02.006.
|
Pre-50s-obge particle state 1 . SNAP output
|
|
7bl3
|
ribosome |
cryo-EM (3.5 Å) |
Nikolay R, Hilal T, Schmidt S, Qin B, Schwefel D,
Vieira-Vieira CH, Mielke T, Burger J, Loerke J, Amikura
K, Flugel T, Ueda T, Selbach M, Deuerling E, Spahn
CMT |
(2021) "Snapshots
of native pre-50S ribosomes reveal a biogenesis factor
network and evolutionary specialization."
Mol.Cell, 81, 1200-1215.e9.
doi: 10.1016/j.molcel.2021.02.006.
|
Pre-50s-obge particle state 2 . SNAP output
|
|
7bl4
|
ribosome |
cryo-EM (2.4 Å) |
Nikolay R, Hilal T, Schmidt S, Qin B, Schwefel D,
Vieira-Vieira CH, Mielke T, Burger J, Loerke J, Amikura
K, Flugel T, Ueda T, Selbach M, Deuerling E, Spahn
CMT |
(2021) "Snapshots
of native pre-50S ribosomes reveal a biogenesis factor
network and evolutionary specialization."
Mol.Cell, 81, 1200-1215.e9.
doi: 10.1016/j.molcel.2021.02.006.
|
In vitro reconstituted 50s-obge-gmppnp-rsfs particle .
SNAP output
|
|
7bl5
|
ribosome |
cryo-EM (3.3 Å) |
Nikolay R, Hilal T, Schmidt S, Qin B, Schwefel D,
Vieira-Vieira CH, Mielke T, Burger J, Loerke J, Amikura
K, Flugel T, Ueda T, Selbach M, Deuerling E, Spahn
CMT |
(2021) "Snapshots
of native pre-50S ribosomes reveal a biogenesis factor
network and evolutionary specialization."
Mol.Cell, 81, 1200-1215.e9.
doi: 10.1016/j.molcel.2021.02.006.
|
Pre-50s-obge particle . SNAP output
|
|
7bl6
|
ribosome |
cryo-EM (4.0 Å) |
Nikolay R, Hilal T, Schmidt S, Qin B, Schwefel D,
Vieira-Vieira CH, Mielke T, Burger J, Loerke J, Amikura
K, Flugel T, Ueda T, Selbach M, Deuerling E, Spahn
CMT |
(2021) "Snapshots
of native pre-50S ribosomes reveal a biogenesis factor
network and evolutionary specialization."
Mol.Cell, 81, 1200-1215.e9.
doi: 10.1016/j.molcel.2021.02.006.
|
50s-obge-gmppnp particle . SNAP output
|
|
7bod
|
ribosome |
cryo-EM (2.88 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
m (body domain) . SNAP
output
|
|
7boe
|
ribosome |
cryo-EM (2.9 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
m (consensus refinement) . SNAP output
|
|
7bof
|
ribosome |
cryo-EM (2.92 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
i (body domain) . SNAP
output
|
|
7bog
|
ribosome |
cryo-EM (2.75 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
e (body domain) . SNAP
output
|
|
7boh
|
ribosome |
cryo-EM (2.82 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Complete bacterial 30s ribosomal subunit assembly
complex state e (+rbfa)(consensus refinement) .
SNAP output
|
|
7boi
|
ribosome |
cryo-EM (2.98 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
f (multibody refinement for body domain of 30s
ribosome) . SNAP
output
|
|
7bt6
|
ribosome |
cryo-EM (3.12 Å) |
Wilson DM, Li Y, LaPeruta A, Gamalinda M, Gao N,
Woolford Jr JL |
(2020) "Structural
insights into assembly of the ribosomal nascent
polypeptide exit tunnel." Nat Commun,
11, 5111. doi: 10.1038/s41467-020-18878-8.
|
cryo-EM structure of pre-60s ribosome from
saccharomyces cerevisiae rpl4delta63-87 strain at 3.12
angstroms resolution(state r1) . SNAP output
|
|
7btb
|
ribosome |
cryo-EM (3.22 Å) |
Wilson DM, Li Y, LaPeruta A, Gamalinda M, Gao N,
Woolford Jr JL |
(2020) "Structural
insights into assembly of the ribosomal nascent
polypeptide exit tunnel." Nat Commun,
11, 5111. doi: 10.1038/s41467-020-18878-8.
|
cryo-EM structure of pre-60s ribosome from
saccharomyces cerevisiae rpl4delta63-87 strain at 3.22
angstroms resolution(state r2) . SNAP output
|
|
7bv2
|
viral protein |
cryo-EM (2.5 Å) |
Yin W, Mao C, Luan X, Shen DD, Shen Q, Su H, Wang X,
Zhou F, Zhao W, Gao M, Chang S, Xie YC, Tian G, Jiang HW,
Tao SC, Shen J, Jiang Y, Jiang H, Xu Y, Zhang S, Zhang Y,
Xu HE |
(2020) "Structural
basis for inhibition of the RNA-dependent RNA
polymerase from SARS-CoV-2 by remdesivir."
Science, 368, 1499-1504. doi:
10.1126/science.abc1560.
|
The nsp12-nsp7-nsp8 complex bound to the
template-primer RNA and triphosphate form of
remdesivir(rtp) . SNAP
output
|
|
7bv8
|
ribosome |
cryo-EM (3.14 Å) |
Wang W, Li W, Ge X, Yan K, Mandava CS, Sanyal S, Gao
N |
(2020) "Loss of
a single methylation in 23S rRNA delays 50S assembly at
multiple late stages and impairs translation initiation
and elongation." Proc.Natl.Acad.Sci.USA,
117, 15609-15619. doi: 10.1073/pnas.1914323117.
|
Mature 50s ribosomal subunit from rrmj knock out e.coli
strain . SNAP output
|
|
7bzf
|
viral protein-RNA |
cryo-EM (3.26 Å) |
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan
L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F,
Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B,
Guddat LW, Gong P, Rao Z |
(2020) "Structural
Basis for RNA Replication by the SARS-CoV-2
Polymerase." Cell, 182,
417-428.e13. doi: 10.1016/j.cell.2020.05.034.
|
Covid-19 RNA-dependent RNA polymerase post-translocated
catalytic complex . SNAP
output
|
|
7c06
|
splicing-RNA |
X-ray (3.02 Å) |
Yoshida H, Park SY, Sakashita G, Nariai Y, Kuwasako
K, Muto Y, Urano T, Obayashi E |
(2020) "Elucidation
of the aberrant 3' splice site selection by
cancer-associated mutations on the U2AF1." Nat
Commun, 11, 4744. doi: 10.1038/s41467-020-18559-6.
|
Crystal structure of yeast u2af1 complex bound to 3'
splice site RNA, 5'-uaggu. . SNAP output
|
|
7c07
|
splicing-RNA |
X-ray (3.2 Å) |
Yoshida H, Park SY, Sakashita G, Nariai Y, Kuwasako
K, Muto Y, Urano T, Obayashi E |
(2020) "Elucidation
of the aberrant 3' splice site selection by
cancer-associated mutations on the U2AF1." Nat
Commun, 11, 4744. doi: 10.1038/s41467-020-18559-6.
|
Crystal structure of yeast u2af1 complex bound to
5'-aaggu RNA. . SNAP
output
|
|
7c08
|
splicing-RNA |
X-ray (3.35 Å) |
Yoshida H, Park SY, Sakashita G, Nariai Y, Kuwasako
K, Muto Y, Urano T, Obayashi E |
(2020) "Elucidation
of the aberrant 3' splice site selection by
cancer-associated mutations on the U2AF1." Nat
Commun, 11, 4744. doi: 10.1038/s41467-020-18559-6.
|
Crystal structure of s34y mutant of yeast u2af1 complex
bound to 3' splice site RNA, 5'-uaggu. . SNAP output
|
|
7c2k
|
viral protein-RNA |
cryo-EM (2.93 Å) |
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan
L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F,
Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B,
Guddat LW, Gong P, Rao Z |
(2020) "Structural
Basis for RNA Replication by the SARS-CoV-2
Polymerase." Cell, 182,
417-428.e13. doi: 10.1016/j.cell.2020.05.034.
|
Covid-19 RNA-dependent RNA polymerase pre-translocated
catalytic complex . SNAP
output
|
|
7c45
|
RNA binding protein-RNA |
X-ray (1.769 Å) |
Gao Y, Liu H, Zhang C, Su S, Chen Y, Chen X, Li Y,
Shao Z, Zhang Y, Shao Q, Li J, Huang Z, Ma J, Gan J |
(2021) "Structural
basis for guide RNA trimming by RNase D ribonuclease in
Trypanosoma brucei." Nucleic Acids Res.,
49, 568-583. doi: 10.1093/nar/gkaa1197.
|
The crystal structure of trypanosoma brucei rnase d
complex with RNA u12 . SNAP output
|
|
7c79
|
RNA binding protein |
cryo-EM (2.5 Å) |
Lan P, Zhou B, Tan M, Li S, Cao M, Wu J, Lei M |
(2020) "Structural
insight into precursor ribosomal RNA processing by
ribonuclease MRP." Science,
369, 656-663. doi: 10.1126/science.abc0149.
|
cryo-EM structure of yeast ribonuclease mrp . SNAP output
|
|
7c7a
|
RNA binding protein |
cryo-EM (2.8 Å) |
Lan P, Zhou B, Tan M, Li S, Cao M, Wu J, Lei M |
(2020) "Structural
insight into precursor ribosomal RNA processing by
ribonuclease MRP." Science,
369, 656-663. doi: 10.1126/science.abc0149.
|
cryo-EM structure of yeast ribonuclease mrp with
substrate its1 . SNAP
output
|
|
7cgf
|
RNA binding protein |
X-ray (1.7 Å) |
Xu Z, Zhao J, Hong M, Zeng C, Guang S, Shi Y |
(2021) "Structural
recognition of the mRNA 3' UTR by PUF-8 restricts the
lifespan of C. elegans." Nucleic Acids
Res., 49, 10082-10097. doi:
10.1093/nar/gkab754.
|
Crystal structure of puf-8 in complex with pbe-RNA .
SNAP output
|
|
7cgg
|
RNA binding protein |
X-ray (2.7 Å) |
Xu Z, Zhao J, Hong M, Zeng C, Guang S, Shi Y |
(2021) "Structural
recognition of the mRNA 3' UTR by PUF-8 restricts the
lifespan of C. elegans." Nucleic Acids
Res., 49, 10082-10097. doi:
10.1093/nar/gkab754.
|
Crystal structure of puf-8 in complex with pbe-RNA .
SNAP output
|
|
7cgh
|
RNA binding protein |
X-ray (2.4 Å) |
Xu Z, Zhao J, Hong M, Zeng C, Guang S, Shi Y |
(2021) "Structural
recognition of the mRNA 3' UTR by PUF-8 restricts the
lifespan of C. elegans." Nucleic Acids
Res., 49, 10082-10097. doi:
10.1093/nar/gkab754.
|
Crystal structure of puf-8 in complex with pbe-RNA .
SNAP output
|
|
7cgi
|
RNA binding protein |
X-ray (2.796 Å) |
Xu Z, Zhao J, Hong M, Zeng C, Guang S, Shi Y |
(2021) "Structural
recognition of the mRNA 3' UTR by PUF-8 restricts the
lifespan of C. elegans." Nucleic Acids
Res., 49, 10082-10097. doi:
10.1093/nar/gkab754.
|
Crystal structure of puf-8 in complex with pbe-RNA .
SNAP output
|
|
7cgj
|
RNA binding protein |
X-ray (2.546 Å) |
Xu Z, Zhao J, Hong M, Zeng C, Guang S, Shi Y |
(2021) "Structural
recognition of the mRNA 3' UTR by PUF-8 restricts the
lifespan of C. elegans." Nucleic Acids
Res., 49, 10082-10097. doi:
10.1093/nar/gkab754.
|
Crystal structure of puf-8 in complex with pbe-RNA .
SNAP output
|
|
7cgk
|
RNA binding protein |
X-ray (2.4 Å) |
Xu Z, Zhao J, Hong M, Zeng C, Guang S, Shi Y |
(2021) "Structural
recognition of the mRNA 3' UTR by PUF-8 restricts the
lifespan of C. elegans." Nucleic Acids
Res., 49, 10082-10097. doi:
10.1093/nar/gkab754.
|
Crystal structure of puf-8 in complex with pbe-RNA .
SNAP output
|
|
7cgl
|
RNA binding protein |
X-ray (2.5 Å) |
Xu Z, Zhao J, Hong M, Zeng C, Guang S, Shi Y |
(2021) "Structural
recognition of the mRNA 3' UTR by PUF-8 restricts the
lifespan of C. elegans." Nucleic Acids
Res., 49, 10082-10097. doi:
10.1093/nar/gkab754.
|
Crystal structure of puf-8 in complex with pbe-RNA .
SNAP output
|
|
7cgm
|
RNA binding protein |
X-ray (2.6 Å) |
Xu Z, Zhao J, Hong M, Zeng C, Guang S, Shi Y |
(2021) "Structural
recognition of the mRNA 3' UTR by PUF-8 restricts the
lifespan of C. elegans." Nucleic Acids
Res., 49, 10082-10097. doi:
10.1093/nar/gkab754.
|
Crystal structure of puf-8 in complex with pbe-RNA .
SNAP output
|
|
7chd
|
transferase |
X-ray (3.804 Å) |
Yashiro Y, Sakaguchi Y, Suzuki T, Tomita K |
(2020) "Mechanism
of aminoacyl-tRNA acetylation by an aminoacyl-tRNA
acetyltransferase AtaT from enterohemorrhagic E.
coli." Nat Commun, 11,
5438. doi: 10.1038/s41467-020-19281-z.
|
Atat complexed with acetyl-methionyl-trnafmet .
SNAP output
|
|
7cpj
|
antibiotic |
cryo-EM (3.3 Å) |
Fujita T, Yokoyama T, Shirouzu M, Taguchi H, Ito T,
Iwasaki S |
(2022) "The
landscape of translational stall sites in bacteria
revealed by monosome and disome profiling."
Rna, 28, 290-302. doi:
10.1261/rna.078188.120.
|
Ycbz-stalled 70s ribosome . SNAP output
|
|
7cpv
|
ribosome |
cryo-EM (3.03 Å) |
Li H, Huo Y, He X, Yao L, Zhang H, Cui Y, Xiao H, Xie
W, Zhang D, Wang Y, Zhang S, Tu H, Cheng Y, Guo Y, Cao X,
Zhu Y, Jiang T, Guo X, Qin Y, Sha J |
(2022) "A male
germ-cell-specific ribosome controls male
fertility." Nature, 612,
725-731. doi: 10.1038/s41586-022-05508-0.
|
cryo-EM structure of 80s ribosome from mouse testis .
SNAP output
|
|
7ctt
|
viral protein |
cryo-EM (3.2 Å) |
Peng Q, Peng R, Yuan B, Wang M, Zhao J, Fu L, Qi J,
Shi Y |
(2021) "Structural
Basis of SARS-CoV-2 Polymerase Inhibition by
Favipiravir." Innovation (N Y),
2, 100080. doi: 10.1016/j.xinn.2021.100080.
|
cryo-EM structure of favipiravir bound to replicating
polymerase complex of sars-cov-2 in the pre-catalytic
state. . SNAP output
|
|
7cxm
|
viral protein-RNA |
cryo-EM (2.9 Å) |
Yan L, Zhang Y, Ge J, Zheng L, Gao Y, Wang T, Jia Z,
Wang H, Huang Y, Li M, Wang Q, Rao Z, Lou Z |
(2020) "Architecture
of a SARS-CoV-2 mini replication and transcription
complex." Nat Commun, 11,
5874. doi: 10.1038/s41467-020-19770-1.
|
Architecture of a sars-cov-2 mini replication and
transcription complex . SNAP output
|
|
7cxn
|
viral protein-RNA |
cryo-EM (3.84 Å) |
Yan L, Zhang Y, Ge J, Zheng L, Gao Y, Wang T, Jia Z,
Wang H, Huang Y, Li M, Wang Q, Rao Z, Lou Z |
(2020) "Architecture
of a SARS-CoV-2 mini replication and transcription
complex." Nat Commun, 11,
5874. doi: 10.1038/s41467-020-19770-1.
|
Architecture of a sars-cov-2 mini replication and
transcription complex . SNAP output
|
|
7cyq
|
viral protein-RNA |
cryo-EM (2.83 Å) |
Yan L, Ge J, Zheng L, Zhang Y, Gao Y, Wang T, Huang
Y, Yang Y, Gao S, Li M, Liu Z, Wang H, Li Y, Chen Y,
Guddat LW, Wang Q, Rao Z, Lou Z |
(2021) "Cryo-EM
Structure of an Extended SARS-CoV-2 Replication and
Transcription Complex Reveals an Intermediate State in
Cap Synthesis." Cell,
184, 184-193.e10. doi: 10.1016/j.cell.2020.11.016.
|
cryo-EM structure of an extended sars-cov-2 replication
and transcription complex reveals an intermediate state
in cap synthesis . SNAP
output
|
|
7d0f
|
transferase-RNA |
cryo-EM (5.0 Å) |
Liu N, Dong X, Hu C, Zeng J, Wang J, Wang J, Wang HW,
Belfort M |
(2020) "Exon and
protein positioning in a pre-catalytic group II intron
RNP primed for splicing." Nucleic Acids
Res., 48, 11185-11198. doi:
10.1093/nar/gkaa773.
|
cryo-EM structure of a pre-catalytic group ii intron
rnp . SNAP output
|
|
7d0g
|
transferase-RNA |
cryo-EM (5.0 Å) |
Liu N, Dong X, Hu C, Zeng J, Wang J, Wang J, Wang HW,
Belfort M |
(2020) "Exon and
protein positioning in a pre-catalytic group II intron
RNP primed for splicing." Nucleic Acids
Res., 48, 11185-11198. doi:
10.1093/nar/gkaa773.
|
cryo-EM structure of a pre-catalytic group ii intron .
SNAP output
|
|
7d1a
|
transferase-RNA |
cryo-EM (3.8 Å) |
Liu N, Dong X, Hu C, Zeng J, Wang J, Wang J, Wang HW,
Belfort M |
(2020) "Exon and
protein positioning in a pre-catalytic group II intron
RNP primed for splicing." Nucleic Acids
Res., 48, 11185-11198. doi:
10.1093/nar/gkaa773.
|
cryo-EM structure of a group ii intron rnp complexed
with its reverse transcriptase . SNAP output
|
|
7d4i
|
ribosome |
cryo-EM (4.0 Å) |
Ye K |
"Cryo-EM structure of 90S small ribosomal precursors
complex with Dhr1." |
cryo-EM structure of 90s small ribosomal precursors
complex with the deah-box RNA helicase dhr1 (state f) .
SNAP output
|
|
7d5s
|
ribosome |
cryo-EM (4.6 Å) |
Ye K |
"Cryo-EM structure of 90S preribosome with inactive
Utp24 (state A2)." |
cryo-EM structure of 90s preribosome with inactive
utp24 (state a2) . SNAP
output
|
|
7d5t
|
ribosome |
cryo-EM (6.0 Å) |
Ye K |
"Cryo-EM structure of 90S preribosome with inactive
Utp24 (state F1)." |
cryo-EM structure of 90s preribosome with inactive
utp24 (state f1) . SNAP
output
|
|
7d63
|
ribosome |
cryo-EM (12.3 Å) |
Ye K |
"Cryo-EM structure of 90S preribosome with inactive
Utp24 (state C)." |
cryo-EM structure of 90s preribosome with inactive
utp24 (state c) . SNAP
output
|
|
7d6z
|
ribosome |
cryo-EM (3.4 Å) |
Akbar S, Bhakta S, Sengupta J |
(2021) "Structural
insights into the interplay of protein biogenesis
factors with the 70S ribosome." Structure,
29, 755-767.e4. doi: 10.1016/j.str.2021.03.005.
|
Molecular model of the cryo-EM structure of 70s
ribosome in complex with peptide deformylase and
trigger factor . SNAP
output
|
|
7d7v
|
RNA |
X-ray (2.8 Å) |
Chen H, Egger M, Xu X, Flemmich L, Krasheninina O,
Sun A, Micura R, Ren A |
(2020) "Structural
distinctions between NAD+ riboswitch domains 1 and 2
determine differential folding and ligand binding."
Nucleic Acids Res., 48,
12394-12406. doi: 10.1093/nar/gkaa1029.
|
Crystal structure of the domain1 of nad+ riboswitch
with nicotinamide adenine dinucleotide (nad+) and u1a
protein . SNAP
output
|
|
7d80
|
ribosome |
cryo-EM (4.1 Å) |
Akbar S, Bhakta S, Sengupta J |
(2021) "Structural
insights into the interplay of protein biogenesis
factors with the 70S ribosome." Structure,
29, 755-767.e4. doi: 10.1016/j.str.2021.03.005.
|
Molecular model of the cryo-EM structure of 70s
ribosome in complex with peptide deformylase, trigger
factor, and methionine aminopeptidase . SNAP output
|
|
7d8c
|
RNA binding protein |
X-ray (3.6 Å) |
Zhang B, Luo D, Li Y, Perculija V, Chen J, Lin J, Ye
Y, Ouyang S |
(2021) "Mechanistic
insights into the R-loop formation and cleavage in
CRISPR-Cas12i1." Nat Commun,
12, 3476. doi: 10.1038/s41467-021-23876-5.
|
Crystal structure of the cas12i1-crrna binary complex .
SNAP output
|
|
7d8o
|
toxin-RNA |
X-ray (2.097 Å) |
Manikandan P, Sandhya S, Nadig K, Paul S, Srinivasan
N, Rothweiler U, Singh M |
(2022) "Identification,
functional characterization, assembly and structure of
ToxIN type III toxin-antitoxin complex from E.
coli." Nucleic Acids Res.,
50, 1687-1700. doi: 10.1093/nar/gkab1264.
|
Crystal structure of e. coli toxin type iii
toxin-antitoxin complex . SNAP output
|
|
7dco
|
splicing |
cryo-EM (2.5 Å) |
Bai R, Wan R, Yan C, Jia Q, Lei J, Shi Y |
(2021) "Mechanism
of spliceosome remodeling by the ATPase/helicase Prp2
and its coactivator Spp2." Science,
371. doi: 10.1126/science.abe8863.
|
cryo-EM structure of the activated spliceosome (bact
complex) at an atomic resolution of 2.5 angstrom .
SNAP output
|
|
7dd3
|
splicing |
cryo-EM (3.2 Å) |
Bai R, Wan R, Yan C, Jia Q, Lei J, Shi Y |
(2021) "Mechanism
of spliceosome remodeling by the ATPase/helicase Prp2
and its coactivator Spp2." Science,
371. doi: 10.1126/science.abe8863.
|
cryo-EM structure of the pre-mrna-loaded deah-box
atpase-helicase prp2 in complex with spp2 . SNAP output
|
|
7dfg
|
viral protein-RNA |
cryo-EM (2.7 Å) |
Yin W, Luan X, Li Z, Xie Y, Zhou Z, Liu J, Gao M,
Wang X, Zhou F, Wang Q, Wang Q, Shen D, Zhang Y, Tian G,
Aisa H, Wei D, Jiang Y, Xiao G, Jiang H, Zhang L, Yu X,
Shen J, Zhang S, Xu H |
"Structural basis for repurpose and design of
nucleotide drugs for treating COVID-19." |
Structure of covid-19 RNA-dependent RNA polymerase
bound to favipiravir . SNAP output
|
|
7dfh
|
viral protein-RNA |
cryo-EM (2.97 Å) |
Yin W, Luan X, Li Z, Xie Y, Zhou Z, Liu J, Gao M,
Wang X, Zhou F, Wang Q, Wang Q, Shen D, Zhang Y, Tian G,
Aisa H, Wei D, Jiang Y, Xiao G, Jiang H, Zhang L, Yu X,
Shen J, Zhang S, Xu H |
"Structural basis for repurpose and design of
nucleotide drugs for treating COVID-19." |
Structure of covid-19 RNA-dependent RNA polymerase
bound to ribavirin . SNAP output
|
|
7dic
|
hydrolase-RNA |
X-ray (2.242 Å) |
Abula A, Li X, Quan X, Yang T, Liu Y, Guo H, Li T, Ji
X |
(2021) "Molecular
mechanism of RNase R substrate sensitivity for RNA
ribose methylation." Nucleic Acids Res.,
49, 4738-4749. doi: 10.1093/nar/gkab202.
|
Mycoplasma genitalium rnase r in complex with
single-stranded RNA . SNAP output
|
|
7did
|
hydrolase-RNA |
X-ray (1.9 Å) |
Abula A, Li X, Quan X, Yang T, Liu Y, Guo H, Li T, Ji
X |
(2021) "Molecular
mechanism of RNase R substrate sensitivity for RNA
ribose methylation." Nucleic Acids Res.,
49, 4738-4749. doi: 10.1093/nar/gkab202.
|
Mycoplasma genitalium rnase r in complex with ribose
methylated single-stranded RNA . SNAP output
|
|
7dkg
|
viral protein-RNA |
X-ray (3.0 Å) |
Tang YS, Xu S, Chen YW, Wang JH, Shaw PC |
(2021) "Crystal
structures of influenza nucleoprotein complexed with
nucleic acid provide insights into the mechanism of RNA
interaction." Nucleic Acids Res.,
49, 4144-4154. doi: 10.1093/nar/gkab203.
|
Influenza h5n1 nucleoprotein (truncated) in complex
with nucleotides . SNAP
output
|
|
7dlz
|
transferase-RNA |
X-ray (3.002 Å) |
Jiang HY, Gao YQ, Zhang L, Chen DR, Gan JH, Murchie
AIH |
(2021) "The identification and characterization of a
selected SAM-dependent methyltransferase ribozyme that
is present in natural sequences." Nat Catal,
4, 872-881. doi: 10.1038/s41929-021-00685-z.
|
Crystal structure of methyltransferase ribozyme .
SNAP output
|
|
7dmq
|
immune system-RNA |
cryo-EM (3.06 Å) |
Wang B, Zhang T, Yin J, Yu Y, Xu W, Ding J, Patel DJ,
Yang H |
(2021) "Structural
basis for self-cleavage prevention by tag:anti-tag
pairing complementarity in type VI Cas13 CRISPR
systems." Mol.Cell, 81,
1100. doi: 10.1016/j.molcel.2020.12.033.
|
cryo-EM structure of lshcas13a-crrna-anti-tag RNA
complex . SNAP
output
|
|
7doi
|
viral protein |
cryo-EM (2.6 Å) |
Yin W, Luan X, Li Z, Xie Y, Zhou Z, Liu J, Gao M,
Wang X, Zhou F, Wang Q, Wang Q, Shen D, Zhang Y, Tian G,
Aisa H, Wei D, Jiang Y, Xiao G, Jiang H, Zhang L, Yu X,
Shen J, Zhang S, Xu H |
"Structural basis for repurpose and design of
nucleotide drugs for treating COVID-19." |
Structure of covid-19 RNA-dependent RNA polymerase
bound to penciclovir. . SNAP output
|
|
7dok
|
viral protein |
cryo-EM (2.73 Å) |
Yin W, Luan X, Li Z, Xie Y, Zhou Z, Liu J, Gao M,
Wang X, Zhou F, Wang Q, Wang Q, Shen D, Zhang Y, Tian G,
Aisa H, Wei D, Jiang Y, Xiao G, Jiang H, Zhang L, Yu X,
Shen J, Zhang S, Xu H |
"Structural basis for repurpose and design of
nucleotide drugs for treating COVID-19." |
Structure of covid-19 RNA-dependent RNA polymerase
(extended conformation) bound to penciclovir . SNAP output
|
|
7dol
|
hydrolase-RNA |
X-ray (2.002 Å) |
Abula A, Li X, Quan X, Yang T, Liu Y, Guo H, Li T, Ji
X |
(2021) "Molecular
mechanism of RNase R substrate sensitivity for RNA
ribose methylation." Nucleic Acids Res.,
49, 4738-4749. doi: 10.1093/nar/gkab202.
|
Mycoplasma genitalium rnase r in complex with
double-stranded RNA . SNAP output
|
|
7dte
|
viral protein-RNA |
cryo-EM (3.0 Å) |
Wu J, Wang H, Liu Q, Li R, Gao Y, Fang X, Zhong Y,
Wang M, Wang Q, Rao Z, Gong P |
(2021) "Remdesivir
overcomes the S861 roadblock in SARS-CoV-2 polymerase
elongation complex." Cell Rep,
37, 109882. doi: 10.1016/j.celrep.2021.109882.
|
Sars-cov-2 rdrp catalytic complex with t33-1 RNA .
SNAP output
|
|
7dug
|
ribosome |
X-ray (3.75 Å) |
Demirci H |
"Crystal structure of the Thermus thermophilus (HB8)
30S ribosomal subunit with mRNA and cognate transfer RNA
anticodon stem-loop and sisomicin derivative N1''TFMS
bound." |
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with mrna and cognate transfer RNA
anticodon stem-loop and sisomicin derivative n1''tfms
bound . SNAP output
|
|
7duh
|
ribosome |
X-ray (3.75 Å) |
Demirci H |
"Crystal structure of the Thermus thermophilus (HB8)
30S ribosomal subunit with mRNA and cognate transfer RNA
anticodon stem-loop and sisomicin derivative N1''AC
bound." |
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with mrna and cognate transfer RNA
anticodon stem-loop and sisomicin derivative n1''ac
bound . SNAP output
|
|
7dui
|
ribosome |
X-ray (3.62 Å) |
Demirci H |
"Crystal structure of the Thermus thermophilus (HB8)
30S ribosomal subunit with mRNA and cognate transfer RNA
anticodon stem-loop and sisomicin derivative N1''PyrS
bound." |
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with mrna and cognate transfer RNA
anticodon stem-loop and sisomicin derivative n1''pyrs
bound . SNAP output
|
|
7duj
|
ribosome |
X-ray (3.75 Å) |
Demirci H |
"Crystal structure of the Thermus thermophilus (HB8)
30S ribosomal subunit with mRNA and cognate transfer RNA
anticodon stem-loop and sisomicin derivative N1,3''Bz
bound." |
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with mrna and cognate transfer RNA
anticodon stem-loop and sisomicin derivative n1,3''bz
bound . SNAP output
|
|
7duk
|
ribosome |
X-ray (3.6 Å) |
Demirci H |
"Crystal structure of the Thermus thermophilus (HB8)
30S ribosomal subunit with mRNA and cognate transfer RNA
anticodon stem-loop and sisomicin derivative N1,3''MS
bound." |
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with mrna and cognate transfer RNA
anticodon stem-loop and sisomicin derivative n1,3''ms
bound . SNAP output
|
|
7dul
|
ribosome |
X-ray (3.62 Å) |
DeMirci H, Destan E |
"Crystal structure of the Thermus thermophilus (HB8)
30S ribosomal subunit with mRNA and cognate transfer RNA
anticodon stem-loop and sisomicin derivative N3''MS
bound." |
Crystal structure of the thermus thermophilus (hb8) 30s
ribosomal subunit with mrna and cognate transfer RNA
anticodon stem-loop and sisomicin derivative n3''ms
bound . SNAP output
|
|
7dvq
|
splicing |
cryo-EM (2.89 Å) |
Bai R, Wan R, Wang L, Xu K, Zhang Q, Lei J, Shi
Y |
(2021) "Structure
of the activated human minor spliceosome."
Science, 371. doi: 10.1126/science.abg0879.
|
cryo-EM structure of the activated human minor
spliceosome (minor bact complex) . SNAP output
|
|
7dwh
|
transferase-RNA |
X-ray (3.1 Å) |
Jiang HY, Gao YQ, Zhang L, Chen DR, Gan JH, Murchie
AIH |
(2021) "The identification and characterization of a
selected SAM-dependent methyltransferase ribozyme that
is present in natural sequences." Nat Catal,
4, 872-881. doi: 10.1038/s41929-021-00685-z.
|
Complex structure of sam-dependent methyltransferase
ribozyme . SNAP
output
|
|
7dxp
|
viral protein-RNA |
X-ray (2.3 Å) |
Tang YS, Xu S, Chen YW, Wang JH, Shaw PC |
(2021) "Crystal
structures of influenza nucleoprotein complexed with
nucleic acid provide insights into the mechanism of RNA
interaction." Nucleic Acids Res.,
49, 4144-4154. doi: 10.1093/nar/gkab203.
|
Influenza h5n1 nucleoprotein in complex with
nucleotides . SNAP
output
|
|
7e8o
|
hydrolase |
X-ray (2.804 Å) |
Li Y, Su S, Gao Y, Lu G, Liu H, Chen X, Shao Z, Zhang
Y, Shao Q, Zhao X, Yang J, Cao C, Lin J, Ma J, Gan J |
(2022) "Crystal
structures and insights into precursor tRNA 5'-end
processing by prokaryotic minimal protein-only RNase
P." Nat Commun, 13, 2290.
doi: 10.1038/s41467-022-30072-6.
|
Crystal structure of proteinaceous rnase p(prorp) from
planctomycetes bacterium gwf2_40_8 complexed with
escherichia coli histidine pre-trna . SNAP output
|
|
7ecv
|
immune system-RNA |
cryo-EM (3.43 Å) |
Liu X, Zhang L, Xiu Y, Gao T, Huang L, Xie Y, Yang L,
Wang W, Wang P, Zhang Y, Yang M, Feng Y |
(2021) "Insights
into the dual functions of AcrIF14 during the
inhibition of type I-F CRISPR-Cas surveillance
complex." Nucleic Acids Res.,
49, 10178-10191. doi: 10.1093/nar/gkab738.
|
The csy-acrif14 complex . SNAP output
|
|
7ed5
|
viral protein |
cryo-EM (2.98 Å) |
Shannon A, Fattorini V, Sama B, Selisko B, Feracci M,
Falcou C, Gauffre P, El Kazzi P, Delpal A, Decroly E,
Alvarez K, Eydoux C, Guillemot JC, Moussa A, Good SS, La
Colla P, Lin K, Sommadossi JP, Zhu Y, Yan X, Shi H,
Ferron F, Canard B |
(2022) "A dual
mechanism of action of AT-527 against SARS-CoV-2
polymerase." Nat Commun,
13, 621. doi: 10.1038/s41467-022-28113-1.
|
A dual mechanism of action of at-527 against sars-cov-2
polymerase . SNAP
output
|
|
7egq
|
viral protein-RNA |
cryo-EM (3.35 Å) |
Yan L, Yang Y, Li M, Zhang Y, Zheng L, Ge J, Huang
YC, Liu Z, Wang T, Gao S, Zhang R, Huang YY, Guddat LW,
Gao Y, Rao Z, Lou Z |
(2021) "Coupling
of N7-methyltransferase and 3'-5' exoribonuclease with
SARS-CoV-2 polymerase reveals mechanisms for capping
and proofreading." Cell,
184, 3474-3485.e11. doi: 10.1016/j.cell.2021.05.033.
|
Co-transcriptional capping machineries in sars-cov-2
rtc: coupling of n7-methyltransferase and 3'-5'
exoribonuclease with polymerase reveals mechanisms for
capping and proofreading . SNAP output
|
|
7eiu
|
RNA binding protein |
X-ray (2.349 Å) |
Shen S, Jian Y, Cai Z, Li F, Lv M, Liu Y, Wu J, Fu C,
Shi Y |
(2022) "Structural
insights reveal the specific recognition of meiRNA by
the Mei2 protein." J Mol Cell Biol,
14. doi: 10.1093/jmcb/mjac029.
|
Crystal structure of mei2 rrm3 in complex with 8mer
meirna . SNAP output
|
|
7eiz
|
viral protein-RNA |
cryo-EM |
Yan L, Yang Y, Li M, Zhang Y, Zheng L, Ge J, Huang
YC, Liu Z, Wang T, Gao S, Zhang R, Huang YY, Guddat LW,
Gao Y, Rao Z, Lou Z |
(2021) "Coupling
of N7-methyltransferase and 3'-5' exoribonuclease with
SARS-CoV-2 polymerase reveals mechanisms for capping
and proofreading." Cell,
184, 3474-3485.e11. doi: 10.1016/j.cell.2021.05.033.
|
Coupling of n7-methyltransferase and 3'-5'
exoribonuclease with sars-cov-2 polymerase reveals
mechanisms for capping and proofreading . SNAP output
|
|
7el9
|
viral protein-RNA |
cryo-EM (3.2 Å) |
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X,
Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi
Y |
(2021) "Cryo-EM
structures of Lassa and Machupo virus polymerases
complexed with cognate regulatory Z proteins identify
targets for antivirals." Nat Microbiol,
6, 921-931. doi: 10.1038/s41564-021-00916-w.
|
Structure of machupo virus l polymerase in complex with
z protein and 3'-vrna (dimeric complex) . SNAP output
|
|
7ela
|
viral protein-RNA |
cryo-EM (3.4 Å) |
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X,
Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi
Y |
(2021) "Cryo-EM
structures of Lassa and Machupo virus polymerases
complexed with cognate regulatory Z proteins identify
targets for antivirals." Nat Microbiol,
6, 921-931. doi: 10.1038/s41564-021-00916-w.
|
Structure of lassa virus polymerase in complex with
3'-vrna and z mutant (f36a) . SNAP output
|
|
7elc
|
viral protein-RNA |
cryo-EM (3.1 Å) |
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X,
Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi
Y |
(2021) "Cryo-EM
structures of Lassa and Machupo virus polymerases
complexed with cognate regulatory Z proteins identify
targets for antivirals." Nat Microbiol,
6, 921-931. doi: 10.1038/s41564-021-00916-w.
|
Structure of monomeric complex of macv l bound to z and
3'-vrna . SNAP
output
|
|
7eld
|
hydrolase |
cryo-EM (4.6 Å) |
Wei X, Ke H, Wen A, Gao B, Shi J, Feng Y |
(2021) "Structural
basis of microRNA processing by Dicer-like 1."
Nat.Plants, 7, 1389-1396.
doi: 10.1038/s41477-021-01000-1.
|
cryo-EM structure of arabidopsis dcl1 in complex with
pri-mirna 166f . SNAP
output
|
|
7ele
|
hydrolase |
cryo-EM (4.9 Å) |
Wei X, Ke H, Wen A, Gao B, Shi J, Feng Y |
(2021) "Structural
basis of microRNA processing by Dicer-like 1."
Nat.Plants, 7, 1389-1396.
doi: 10.1038/s41477-021-01000-1.
|
cryo-EM structure of arabidopsis dcl1 in complex with
pre-mirna 166f . SNAP
output
|
|
7elh
|
viral protein-transferase-RNA |
cryo-EM (3.3 Å) |
Pan M, Alvarez-Cabrera AL, Kang JS, Wang L, Fan C,
Zhou ZH |
(2021) "Asymmetric
reconstruction of mammalian reovirus reveals
interactions among RNA, transcriptional factor mu2 and
capsid proteins." Nat Commun,
12, 4176. doi: 10.1038/s41467-021-24455-4.
|
In situ structure of transcriptional enzyme complex and
capsid shell protein of mammalian reovirus at
initiation state . SNAP
output
|
|
7elm
|
immune system-RNA |
cryo-EM (2.88 Å) |
Yang L, Zhang L, Yin P, Ding H, Xiao Y, Zeng J, Wang
W, Zhou H, Wang Q, Zhang Y, Chen Z, Yang M, Feng Y |
(2022) "Insights
into the inhibition of type I-F CRISPR-Cas system by a
multifunctional anti-CRISPR protein AcrIF24."
Nat Commun, 13, 1931. doi:
10.1038/s41467-022-29581-1.
|
Structure of csy-acrif24 . SNAP output
|
|
7eni
|
viral protein-RNA |
X-ray (2.632 Å) |
Wang Y, Li X |
"Crystal structure of cas and anti-cas protein
complex." |
Crystal structure of cas and anti-cas protein complex .
SNAP output
|
|
7enr
|
viral protein-RNA |
X-ray (4.205 Å) |
Wang Y, Li X |
"Crystal structure of cas and anti-cas protein
complex." |
Crystal structure of cas and anti-cas protein complex .
SNAP output
|
|
7evo
|
splicing |
cryo-EM (2.5 Å) |
Zhang X, Zhan X, Bian T, Yang F, Li P, Lu Y, Xing Z,
Fan R, Zhang QC, Shi Y |
(2024) "Structural
insights into branch site proofreading by human
spliceosome." Nat.Struct.Mol.Biol. doi:
10.1038/s41594-023-01188-0.
|
The cryo-EM structure of the human 17s u2 snrnp .
SNAP output
|
|
7ewq
|
nuclear protein |
cryo-EM (3.5 Å) |
Shan H, Su X, Li T, Qin Y, Zhang N, Yang L, Ma L, Bai
Y, Qi L, Liu Y, Shen QT |
(2021) "Structural
plasticity of mumps virus nucleocapsids with cryo-EM
structures." Commun Biol,
4, 833. doi: 10.1038/s42003-021-02362-0.
|
Structure of mumps virus nucleocapsid ring . SNAP output
|
|
7exa
|
nuclear protein |
cryo-EM (2.9 Å) |
Shan H, Su X, Li T, Qin Y, Zhang N, Yang L, Ma L, Bai
Y, Qi L, Liu Y, Shen QT |
(2021) "Structural
plasticity of mumps virus nucleocapsids with cryo-EM
structures." Commun Biol,
4, 833. doi: 10.1038/s42003-021-02362-0.
|
Structure of mumps virus nucleoprotein without c-arm .
SNAP output
|
|
7f0d
|
ribosome |
cryo-EM (3.3 Å) |
Zhang W, Li Z, Sun Y, Cui P, Liang J, Xing Q, Wu J,
Xu Y, Zhang W, Zhang Y, He L, Gao N |
(2022) "Cryo-EM
structure of Mycobacterium tuberculosis 50S ribosomal
subunit bound with clarithromycin reveals dynamic and
specific interactions with macrolides." Emerg
Microbes Infect, 11, 293-305.
doi: 10.1080/22221751.2021.2022439.
|
cryo-EM structure of mycobacterium tuberculosis 50s
ribosome subunit bound with clarithromycin . SNAP output
|
|
7f1m
|
viral protein |
cryo-EM (3.1 Å) |
Fujita-Fujiharu Y, Sugita Y, Takamatsu Y, Houri K,
Igarashi M, Muramoto Y, Nakano M, Tsunoda Y, Taniguchi I,
Becker S, Noda T |
(2022) "Structural
insight into Marburg virus nucleoprotein-RNA complex
formation." Nat Commun,
13, 1191. doi: 10.1038/s41467-022-28802-x.
|
Marburg virus nucleoprotein-RNA complex . SNAP output
|
|
7f36
|
transferase |
X-ray (3.098 Å) |
Yashiro Y, Zhang C, Sakaguchi Y, Suzuki T, Tomita
K |
(2021) "Molecular basis of glycyl-tRNAGly acetylation
by TacT from Salmonella Typhimurium." Cell
Rep, 37, 110130. doi: 10.1016/j.celrep.2021.110130.
|
Tact complexed with acetyl-glycyl-trnagly . SNAP output
|
|
7f3i
|
RNA binding protein-RNA |
X-ray (2.25 Å) |
Zhang Y, Huang Y |
"Crystal structure of human YBX2 CSD in complex with
m5C RNA in space group P212121." |
Crystal structure of human ybx2 csd in complex with m5c
RNA in space group p212121 . SNAP output
|
|
7f3j
|
RNA binding protein-RNA |
X-ray (1.95 Å) |
Zhang Y, Huang Y |
"Crystal structure of human YBX2 CSD in complex with
m5C RNA in space group P1." |
Crystal structure of human ybx2 csd in complex with m5c
RNA in space group p1 . SNAP output
|
|
7f3k
|
RNA binding protein-RNA |
X-ray (1.76 Å) |
Zhang Y, Huang Y |
"Crystal structure of human YBX2 CSD in complex with
m5C RNA in space group P21212." |
Crystal structure of human ybx2 csd in complex with m5c
RNA in space group p21212 . SNAP output
|
|
7f3l
|
RNA binding protein-RNA |
X-ray (1.88 Å) |
Zhang Y, Huang Y |
"Crystal structure of human YBX2 CSD in complex with
m5C RNA in space group P62." |
Crystal structure of human ybx2 csd in complex with m5c
RNA in space group p62 . SNAP output
|
|
7f49
|
blood clotting |
X-ray (2.09 Å) |
Zhu S, Gilbert CJ |
(2020) "The
development and characterization of a long acting
anti-thrombotic von Willebrand factor (VWF)
aptamer." J Thromb Haemost.,
18, 1113-1123. doi: 10.1111/jth.14755.
|
Von willebrand factor (vwf) a1 domain with bt-100
aptamer RNA . SNAP
output
|
|
7jhy
|
immune system-RNA |
cryo-EM (3.9 Å) |
Zhou Y, Bravo JPK, Taylor HN, Steens JA, Jackson RN,
Staals RHJ, Taylor DW |
(2021) "Structure
of a type IV CRISPR-Cas ribonucleoprotein complex."
Iscience, 24, 102201. doi:
10.1016/j.isci.2021.102201.
|
Type iv-b crispr complex . SNAP output
|
|
7jil
|
ribosome |
cryo-EM (2.8 Å) |
Jha V, Roy B, Jahagirdar D, McNutt ZA, Shatoff EA,
Boleratz BL, Watkins DE, Bundschuh R, Basu K, Ortega J,
Fredrick K |
(2021) "Structural
basis of sequestration of the anti-Shine-Dalgarno
sequence in the Bacteroidetes ribosome."
Nucleic Acids Res., 49,
547-567. doi: 10.1093/nar/gkaa1195.
|
70s ribosome flavobacterium johnsoniae . SNAP output
|
|
7jl0
|
hydrolase-immune system-RNA |
cryo-EM (4.3 Å) |
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik
HS, Hur S |
(2021) "Structural
analysis of RIG-I-like receptors reveals ancient rules
of engagement between diverse RNA helicases and TRIM
ubiquitin ligases." Mol.Cell,
81, 599-613.e8. doi: 10.1016/j.molcel.2020.11.047.
|
cryo-EM structure of mda5-dsrna in complex with trim65
pspry domain (monomer) . SNAP output
|
|
7jl1
|
hydrolase-transferase-RNA |
cryo-EM (3.9 Å) |
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik
HS, Hur S |
(2021) "Structural
analysis of RIG-I-like receptors reveals ancient rules
of engagement between diverse RNA helicases and TRIM
ubiquitin ligases." Mol.Cell,
81, 599-613.e8. doi: 10.1016/j.molcel.2020.11.047.
|
cryo-EM structure of rig-i:dsrna in complex with riplet
pryspry domain (monomer) . SNAP output
|
|
7jl2
|
hydrolase-immune system-RNA |
cryo-EM (4.3 Å) |
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik
HS, Hur S |
(2021) "Structural
analysis of RIG-I-like receptors reveals ancient rules
of engagement between diverse RNA helicases and TRIM
ubiquitin ligases." Mol.Cell,
81, 599-613.e8. doi: 10.1016/j.molcel.2020.11.047.
|
cryo-EM structure of mda5-dsrna filament in complex
with trim65 pspry domain (trimer) . SNAP output
|
|
7jl3
|
hydrolase-transferase-RNA |
cryo-EM (4.2 Å) |
Kato K, Ahmad S, Zhu Z, Young JM, Mu X, Park S, Malik
HS, Hur S |
(2021) "Structural
analysis of RIG-I-like receptors reveals ancient rules
of engagement between diverse RNA helicases and TRIM
ubiquitin ligases." Mol.Cell,
81, 599-613.e8. doi: 10.1016/j.molcel.2020.11.047.
|
cryo-EM structure of rig-i:dsrna filament in complex
with riplet pryspry domain (trimer) . SNAP output
|
|
7jqb
|
ribosome-viral protein |
cryo-EM (2.7 Å) |
Yuan S, Peng L, Park JJ, Hu Y, Devarkar SC, Dong MB,
Shen Q, Wu S, Chen S, Lomakin IB, Xiong Y |
(2020) "Nonstructural
Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity
Factor Redirecting Host Protein Synthesis Machinery
toward Viral RNA." Mol.Cell,
80, 1055-1066.e6. doi: 10.1016/j.molcel.2020.10.034.
|
Sars-cov-2 nsp1 and rabbit 40s ribosome complex .
SNAP output
|
|
7jqc
|
ribosome-viral protein |
cryo-EM (3.3 Å) |
Yuan S, Peng L, Park JJ, Hu Y, Devarkar SC, Dong MB,
Shen Q, Wu S, Chen S, Lomakin IB, Xiong Y |
(2020) "Nonstructural
Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity
Factor Redirecting Host Protein Synthesis Machinery
toward Viral RNA." Mol.Cell,
80, 1055-1066.e6. doi: 10.1016/j.molcel.2020.10.034.
|
Sars-cov-2 nsp1, crpv ires and rabbit 40s ribosome
complex . SNAP
output
|
|
7jql
|
ribosome |
X-ray (3.0 Å) |
Mardirossian M, Sola R, Beckert B, Valencic E, Collis
DWP, Borisek J, Armas F, Di Stasi A, Buchmann J, Syroegin
EA, Polikanov YS, Magistrato A, Hilpert K, Wilson DN,
Scocchi M |
(2020) "Peptide
Inhibitors of Bacterial Protein Synthesis with Broad
Spectrum and SbmA-Independent Bactericidal Activity
against Clinical Pathogens." J.Med.Chem.,
63, 9590-9602. doi: 10.1021/acs.jmedchem.0c00665.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with bac7-001, mrna, and deacylated
p-site trna at 3.00a resolution . SNAP output
|
|
7jqm
|
ribosome |
X-ray (3.05 Å) |
Mardirossian M, Sola R, Beckert B, Valencic E, Collis
DWP, Borisek J, Armas F, Di Stasi A, Buchmann J, Syroegin
EA, Polikanov YS, Magistrato A, Hilpert K, Wilson DN,
Scocchi M |
(2020) "Peptide
Inhibitors of Bacterial Protein Synthesis with Broad
Spectrum and SbmA-Independent Bactericidal Activity
against Clinical Pathogens." J.Med.Chem.,
63, 9590-9602. doi: 10.1021/acs.jmedchem.0c00665.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with bac7-002, mrna, and deacylated
p-site trna at 3.05a resolution . SNAP output
|
|
7jss
|
ribosome-translation |
cryo-EM (3.7 Å) |
Carbone CE, Demo G, Madireddy R, Svidritskiy E,
Korostelev AA |
(2020) "ArfB can
displace mRNA to rescue stalled ribosomes." Nat
Commun, 11, 5552. doi: 10.1038/s41467-020-19370-z.
|
Arfb rescue of a 70s ribosome stalled on truncated mrna
with a partial a-site codon (+2-ii) . SNAP output
|
|
7jsw
|
ribosome-translation |
cryo-EM (3.8 Å) |
Carbone CE, Demo G, Madireddy R, Svidritskiy E,
Korostelev AA |
(2020) "ArfB can
displace mRNA to rescue stalled ribosomes." Nat
Commun, 11, 5552. doi: 10.1038/s41467-020-19370-z.
|
Arfb rescue of a 70s ribosome stalled on truncated mrna
with a partial a-site codon (+2-iii) . SNAP output
|
|
7jsz
|
ribosome-translation |
cryo-EM (3.7 Å) |
Carbone CE, Demo G, Madireddy R, Svidritskiy E,
Korostelev AA |
(2020) "ArfB can
displace mRNA to rescue stalled ribosomes." Nat
Commun, 11, 5552. doi: 10.1038/s41467-020-19370-z.
|
Arfb rescue of a 70s ribosome stalled on truncated mrna
with a partial a-site codon (+2-iv) . SNAP output
|
|
7jt1
|
ribosome |
cryo-EM (3.3 Å) |
Carbone CE, Demo G, Madireddy R, Svidritskiy E,
Korostelev AA |
(2020) "ArfB can
displace mRNA to rescue stalled ribosomes." Nat
Commun, 11, 5552. doi: 10.1038/s41467-020-19370-z.
|
70s ribosome stalled on long mrna with arfb-1 and
arfb-2 bound (+9-iii) . SNAP output
|
|
7jt2
|
ribosome |
cryo-EM (3.5 Å) |
Carbone CE, Demo G, Madireddy R, Svidritskiy E,
Korostelev AA |
(2020) "ArfB can
displace mRNA to rescue stalled ribosomes." Nat
Commun, 11, 5552. doi: 10.1038/s41467-020-19370-z.
|
70s ribosome stalled on long mrna with arfb bound in
the a site . SNAP
output
|
|
7jt3
|
ribosome |
cryo-EM (3.7 Å) |
Carbone CE, Demo G, Madireddy R, Svidritskiy E,
Korostelev AA |
(2020) "ArfB can
displace mRNA to rescue stalled ribosomes." Nat
Commun, 11, 5552. doi: 10.1038/s41467-020-19370-z.
|
Rotated 70s ribosome stalled on long mrna with arfb-1
and arfb-2 bound in the a site (+9-iv) . SNAP output
|
|
7jyy
|
viral protein-RNA |
X-ray (2.05 Å) |
Minasov G, Rosas-Lemus M, Shuvalova L, Inniss NL,
Brunzelle JS, Daczkowski CM, Hoover P, Mesecar AD,
Satchell KJF |
(2021) "Mn 2+
coordinates Cap-0-RNA to align substrates for efficient
2'- O -methyl transfer by SARS-CoV-2 nsp16."
Sci.Signal., 14. doi:
10.1126/scisignal.abh2071.
|
Crystal structure of sars-cov-2 nsp16-10 heterodimer in
complex with (m7gpppa)pupupapapa (cap-0) and
s-adenosylmethionine (sam). . SNAP output
|
|
7jz0
|
viral protein-RNA |
X-ray (2.15 Å) |
Rosas-Lemus M, Minasov G, Shuvalova L, Inniss N,
Kiryukhina O, Brunzelle J, Satchell KJF |
(2020) "Structure of SARS-CoV-2 2'-O-methyltransferase
heterodimer with RNA Cap analog and sulfates bound
reveals new strategies for structure-based inhibitor
design." Biorxiv. doi: 10.1101/2020.08.03.234716.
|
Crystal structure of sars-cov-2 nsp16-10 heterodimer in
complex with (m7gpppa2m)pupupapapa (cap-1) and
s-adenosyl-l-homocysteine (sah). . SNAP output
|
|
7jzw
|
hydrolase |
cryo-EM (3.2 Å) |
Gabel C, Li Z, Zhang H, Chang L |
(2021) "Structural
basis for inhibition of the type I-F CRISPR-Cas
surveillance complex by AcrIF4, AcrIF7 and
AcrIF14." Nucleic Acids Res.,
49, 584-594. doi: 10.1093/nar/gkaa1199.
|
cryo-EM structure of crispr-cas surveillance complex
with acrif4 . SNAP
output
|
|
7jzx
|
hydrolase-RNA |
cryo-EM (3.4 Å) |
Gabel C, Li Z, Zhang H, Chang L |
(2021) "Structural
basis for inhibition of the type I-F CRISPR-Cas
surveillance complex by AcrIF4, AcrIF7 and
AcrIF14." Nucleic Acids Res.,
49, 584-594. doi: 10.1093/nar/gkaa1199.
|
cryo-EM structure of crispr-cas surveillance complex
with acrif7 . SNAP
output
|
|
7jzy
|
hydrolase-RNA |
cryo-EM (3.6 Å) |
Chang L, Li Z, Gabel C |
"CryoEM structure of a CRISPR-Cas complex." |
Cryoem structure of a crispr-cas complex . SNAP output
|
|
7jzz
|
hydrolase-RNA |
cryo-EM (3.2 Å) |
Gabel C, Li Z, Zhang H, Chang L |
(2021) "Structural
basis for inhibition of the type I-F CRISPR-Cas
surveillance complex by AcrIF4, AcrIF7 and
AcrIF14." Nucleic Acids Res.,
49, 584-594. doi: 10.1093/nar/gkaa1199.
|
cryo-EM structure of crispr-cas surveillance complex
with acrif14 . SNAP
output
|
|
7k00
|
ribosome |
cryo-EM (1.98 Å) |
Watson ZL, Ward FR, Meheust R, Ad O, Schepartz A,
Banfield JF, Cate JH |
(2020) "Structure
of the bacterial ribosome at 2 angstrom
resolution." Elife, 9.
doi: 10.7554/eLife.60482.
|
Structure of the bacterial ribosome at 2 angstrom
resolution . SNAP
output
|
|
7k50
|
ribosome |
cryo-EM (3.4 Å) |
Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE,
Svidritskiy E, Hou YM, Korostelev AA |
(2021) "Structural
basis for +1 ribosomal frameshifting during
EF-G-catalyzed translocation." Nat Commun,
12, 4644. doi: 10.1038/s41467-021-24911-1.
|
Pre-translocation non-frameshifting(cca-a) complex
(structure i) . SNAP
output
|
|
7k51
|
ribosome |
cryo-EM (3.5 Å) |
Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE,
Svidritskiy E, Hou YM, Korostelev AA |
(2021) "Structural
basis for +1 ribosomal frameshifting during
EF-G-catalyzed translocation." Nat Commun,
12, 4644. doi: 10.1038/s41467-021-24911-1.
|
Mid-translocated non-frameshifting(cca-a) complex with
ef-g and gdpcp (structure ii) . SNAP output
|
|
7k52
|
ribosome |
cryo-EM (3.4 Å) |
Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE,
Svidritskiy E, Hou YM, Korostelev AA |
(2021) "Structural
basis for +1 ribosomal frameshifting during
EF-G-catalyzed translocation." Nat Commun,
12, 4644. doi: 10.1038/s41467-021-24911-1.
|
Near post-translocated non-frameshifting(cca-a) complex
with ef-g and gdpcp (structure iii) . SNAP output
|
|
7k53
|
ribosome |
cryo-EM (3.2 Å) |
Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE,
Svidritskiy E, Hou YM, Korostelev AA |
(2021) "Structural
basis for +1 ribosomal frameshifting during
EF-G-catalyzed translocation." Nat Commun,
12, 4644. doi: 10.1038/s41467-021-24911-1.
|
Pre-translocation +1-frameshifting(ccc-a) complex
(structure i-fs) . SNAP
output
|
|
7k54
|
ribosome |
cryo-EM (3.2 Å) |
Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE,
Svidritskiy E, Hou YM, Korostelev AA |
(2021) "Structural
basis for +1 ribosomal frameshifting during
EF-G-catalyzed translocation." Nat Commun,
12, 4644. doi: 10.1038/s41467-021-24911-1.
|
Mid-translocated +1-frameshifting(ccc-a) complex with
ef-g and gdpcp (structure ii-fs) . SNAP output
|
|
7k55
|
ribosome |
cryo-EM (3.3 Å) |
Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE,
Svidritskiy E, Hou YM, Korostelev AA |
(2021) "Structural
basis for +1 ribosomal frameshifting during
EF-G-catalyzed translocation." Nat Commun,
12, 4644. doi: 10.1038/s41467-021-24911-1.
|
Near post-translocated +1-frameshifting(ccc-a) complex
with ef-g and gdpcp (structure iii-fs) . SNAP output
|
|
7k5i
|
ribosome-viral protein |
cryo-EM (2.9 Å) |
Shi M, Wang L, Fontana P, Vora S, Zhang Y, Fu TM,
Lieberman J, Wu H |
(2020) "SARS-CoV-2
Nsp1 suppresses host but not viral translation through
a bipartite mechanism." Biorxiv. doi:
10.1101/2020.09.18.302901.
|
Sars-cov-2 nsp1 in complex with human 40s ribosome .
SNAP output
|
|
7k5l
|
viral protein |
X-ray (1.38 Å) |
Landeras-Bueno S, Wasserman H, Oliveira G, VanAernum
ZL, Busch F, Salie ZL, Wysocki VH, Andersen K, Saphire
EO |
(2021) "Cellular
mRNA triggers structural transformation of Ebola virus
matrix protein VP40 to its essential regulatory
form." Cell Rep, 35,
108986. doi: 10.1016/j.celrep.2021.108986.
|
Ebola virus vp40 octameric ring generated by an RNA
oligonucleotide . SNAP
output
|
|
7k98
|
ligase-RNA |
X-ray (2.19 Å) |
Michalska K, Jedrzejczak R, Wower J, Chang C,
Baragana B, Gilbert IH, Forte B, Joachimiak A |
(2021) "Mycobacterium
tuberculosis Phe-tRNA synthetase: structural insights
into tRNA recognition and aminoacylation."
Nucleic Acids Res., 49,
5351-5368. doi: 10.1093/nar/gkab272.
|
Preaminoacylation complex of m. tuberculosis phers with
cognate precursor trna and
5'-o-(n-phenylalanyl)sulfamoyl-adenosine (f-ams) .
SNAP output
|
|
7k9d
|
RNA-binding protein-RNA |
X-ray (2.098 Å) |
Yang Y, Harris KA, Widner DL, Breaker RR |
(2021) "Structure
of a bacterial OapB protein with its OLE RNA target
gives insights into the architecture of the OLE
ribonucleoprotein complex."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2020393118.
|
Crystal structure of bacillus halodurans oapb in
complex with its ole RNA target (crystal form i) .
SNAP output
|
|
7k9e
|
RNA-binding protein-RNA |
X-ray (2.1 Å) |
Yang Y, Harris KA, Widner DL, Breaker RR |
(2021) "Structure
of a bacterial OapB protein with its OLE RNA target
gives insights into the architecture of the OLE
ribonucleoprotein complex."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2020393118.
|
Crystal structure of bacillus halodurans oapb in
complex with its ole RNA target (crystal form ii) .
SNAP output
|
|
7k9m
|
ligase-RNA |
X-ray (2.5 Å) |
Michalska K, Jedrzejczak R, Wower J, Chang C,
Baragana B, Gilbert IH, Forte B, Joachimiak A |
(2021) "Mycobacterium
tuberculosis Phe-tRNA synthetase: structural insights
into tRNA recognition and aminoacylation."
Nucleic Acids Res., 49,
5351-5368. doi: 10.1093/nar/gkab272.
|
Crystal structure of the complex of m. tuberculosis
phers with cognate precursor trna and
5'-o-(n-phenylalanyl)sulfamoyl-adenosine . SNAP output
|
|
7ka0
|
ligase-RNA |
X-ray (2.4 Å) |
Michalska K, Jedrzejczak R, Wower J, Chang C,
Baragana B, Gilbert IH, Forte B, Joachimiak A |
(2021) "Mycobacterium
tuberculosis Phe-tRNA synthetase: structural insights
into tRNA recognition and aminoacylation."
Nucleic Acids Res., 49,
5351-5368. doi: 10.1093/nar/gkab272.
|
Crystal structure of the complex of m. tuberculosis
phers with cognate precursor trna and phenylalanine .
SNAP output
|
|
7kab
|
ligase-RNA |
X-ray (2.5 Å) |
Michalska K, Jedrzejczak R, Wower J, Chang C,
Baragana B, Gilbert IH, Forte B, Joachimiak A |
(2021) "Mycobacterium
tuberculosis Phe-tRNA synthetase: structural insights
into tRNA recognition and aminoacylation."
Nucleic Acids Res., 49,
5351-5368. doi: 10.1093/nar/gkab272.
|
M. tuberculosis phers complex with cognate precursor
trna and phenylalanine . SNAP output
|
|
7kfn
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Doherty EE, Wilcox XE, van Sint Fiet L, Kemmel C,
Turunen JJ, Klein B, Tantillo DJ, Fisher AJ, Beal PA |
(2021) "Rational
Design of RNA Editing Guide Strands: Cytidine Analogs
at the Orphan Position." J.Am.Chem.Soc.,
143, 6865-6876. doi: 10.1021/jacs.0c13319.
|
Structure of human adenosine deaminase acting on dsrna
(adar2) bound to dsrna containing a 2'-deoxy benner's
base z opposite the edited base . SNAP output
|
|
7kgb
|
ribosome-antibiotic |
cryo-EM (2.7 Å) |
Zhang J, Lair C, Roubert C, Amaning K, Barrio MB,
Benedetti Y, Cui Z, Xing Z, Li X, Franzblau SG, Baurin N,
Bordon-Pallier F, Cantalloube C, Sans S, Silve S, Blanc
I, Fraisse L, Rak A, Jenner LB, Yusupova G, Yusupov M,
Zhang J, Kaneko T, Yang TJ, Fotouhi N, Nuermberger E,
Tyagi S, Betoudji F, Upton A, Sacchettini JC, Lagrange
S |
(2023) "Discovery
of natural-product-derived sequanamycins as potent oral
anti-tuberculosis agents." Cell. doi:
10.1016/j.cell.2023.01.043.
|
Cryoem structure of a2296-methylated mycobacterium
tuberculosis ribosome bound with seq-9 . SNAP output
|
|
7kha
|
RNA binding protein-RNA |
cryo-EM (3.13 Å) |
O'Brien RE, Santos IC, Wrapp D, Bravo JPK, Schwartz
EA, Brodbelt JS, Taylor DW |
(2020) "Structural
basis for assembly of non-canonical small subunits into
type I-C Cascade." Nat Commun,
11, 5931. doi: 10.1038/s41467-020-19785-8.
|
cryo-EM structure of the desulfovibrio vulgaris type
i-c apo cascade . SNAP
output
|
|
7ki3
|
hydrolase-RNA |
X-ray (3.0 Å) |
Gebert LFR, Law M, MacRae IJ |
(2021) "A
structured RNA motif locks Argonaute2:miR-122 onto the
5' end of the HCV genome." Nat Commun,
12, 6836. doi: 10.1038/s41467-021-27177-9.
|
Human argonaute2:mir-122 bound to the hcv genotype 1a
site-1 RNA . SNAP
output
|
|
7kjt
|
RNA binding protein-RNA |
X-ray (3.34 Å) |
Beenstock J, Ona SM, Porat J, Orlicky S, Wan LCK,
Ceccarelli DF, Maisonneuve P, Szilard RK, Yin Z,
Setiaputra D, Mao DYL, Khan M, Raval S, Schriemer DC,
Bayfield MA, Durocher D, Sicheri F |
(2020) "A
substrate binding model for the KEOPS tRNA modifying
complex." Nat Commun, 11,
6233. doi: 10.1038/s41467-020-19990-5.
|
Keops trna modifying sub-complex of archaeal cgi121 and
trna . SNAP output
|
|
7kjv
|
viral protein-RNA |
cryo-EM (2.8 Å) |
Ha B, Larsen KP, Zhang J, Fu Z, Montabana E, Jackson
LN, Chen DH, Puglisi EV |
(2021) "High-resolution
view of HIV-1 reverse transcriptase initiation
complexes and inhibition by NNRTI drugs." Nat
Commun, 12, 2500. doi: 10.1038/s41467-021-22628-9.
|
Structure of hiv-1 reverse transcriptase initiation
complex core . SNAP
output
|
|
7kjw
|
viral protein-RNA |
cryo-EM (2.9 Å) |
Ha B, Larsen KP, Zhang J, Fu Z, Montabana E, Jackson
LN, Chen DH, Puglisi EV |
(2021) "High-resolution
view of HIV-1 reverse transcriptase initiation
complexes and inhibition by NNRTI drugs." Nat
Commun, 12, 2500. doi: 10.1038/s41467-021-22628-9.
|
Structure of hiv-1 reverse transcriptase initiation
complex core with efavirenz . SNAP output
|
|
7kjx
|
viral protein-RNA |
cryo-EM (3.1 Å) |
Ha B, Larsen KP, Zhang J, Fu Z, Montabana E, Jackson
LN, Chen DH, Puglisi EV |
(2021) "High-resolution
view of HIV-1 reverse transcriptase initiation
complexes and inhibition by NNRTI drugs." Nat
Commun, 12, 2500. doi: 10.1038/s41467-021-22628-9.
|
Structure of hiv-1 reverse transcriptase initiation
complex core with nevirapine . SNAP output
|
|
7kkv
|
RNA-binding protein-RNA |
X-ray (2.0 Å) |
Yang Y, Harris KA, Widner DL, Breaker RR |
(2021) "Structure
of a bacterial OapB protein with its OLE RNA target
gives insights into the architecture of the OLE
ribonucleoprotein complex."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2020393118.
|
Crystal structure of bacillus halodurans oapb in
complex with its ole RNA target (native, crystal form
i) . SNAP output
|
|
7kl3
|
viral protein-RNA |
X-ray (1.99 Å) |
Kumar G, Cuypers M, Webby RR, Webb TR, White SW |
(2021) "Structural
insights into the substrate specificity of the
endonuclease activity of the influenza virus
cap-snatching mechanism." Nucleic Acids
Res., 49, 1609-1618. doi:
10.1093/nar/gkaa1294.
|
The crystal structure of the 2009-h1n1-california pa
endonuclease mutant e119d bound to RNA oligomer ag*cauc
(*uncleaveable bond, -uc disordered) . SNAP output
|
|
7krn
|
transferase-hydrolase-RNA |
cryo-EM (3.4 Å) |
Malone B, Chen J, Wang Q, Llewellyn E, Choi YJ,
Olinares PDB, Cao X, Hernandez C, Eng ET, Chait BT, Shaw
DE, Landick R, Darst SA, Campbell EA |
(2021) "Structural
basis for backtracking by the SARS-CoV-2
replication-transcription complex."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2102516118.
|
Structure of sars-cov-2 backtracked complex bound to
nsp13 helicase - nsp13(1)-btc . SNAP output
|
|
7kro
|
transferase-hydrolase-RNA |
cryo-EM (3.6 Å) |
Malone B, Chen J, Wang Q, Llewellyn E, Choi YJ,
Olinares PDB, Cao X, Hernandez C, Eng ET, Chait BT, Shaw
DE, Landick R, Darst SA, Campbell EA |
(2021) "Structural
basis for backtracking by the SARS-CoV-2
replication-transcription complex."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2102516118.
|
Structure of sars-cov-2 backtracked complex complex
bound to nsp13 helicase - nsp13(2)-btc . SNAP output
|
|
7krp
|
transferase-RNA |
cryo-EM (3.2 Å) |
Malone B, Chen J, Wang Q, Llewellyn E, Choi YJ,
Olinares PDB, Cao X, Hernandez C, Eng ET, Chait BT, Shaw
DE, Landick R, Darst SA, Campbell EA |
(2021) "Structural
basis for backtracking by the SARS-CoV-2
replication-transcription complex."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2102516118.
|
Structure of sars-cov-2 backtracked complex complex
bound to nsp13 helicase - btc (local refinement) .
SNAP output
|
|
7kwg
|
ribosome |
cryo-EM (3.75 Å) |
Belinite M, Khusainov I, Soufari H, Marzi S, Romby P,
Yusupov M, Hashem Y |
(2021) "Stabilization
of Ribosomal RNA of the Small Subunit by Spermidine in
Staphylococcus aureus ." Front Mol Biosci,
8, 738752. doi: 10.3389/fmolb.2021.738752.
|
Staphylococcus aureus 30s ribosomal subunit in presence
of spermidine . SNAP
output
|
|
7kx7
|
hydrolase,RNA binding protein-RNA |
cryo-EM (3.8 Å) |
Anzelon TA, Chowdhury S, Hughes SM, Xiao Y, Lander
GC, MacRae IJ |
(2021) "Structural
basis for piRNA targeting." Nature,
597, 285-289. doi: 10.1038/s41586-021-03856-x.
|
cryo-EM structure of ephydatia fluviatilis piwia-pirna
complex . SNAP
output
|
|
7kx9
|
hydrolase,RNA binding protein-RNA |
cryo-EM (3.5 Å) |
Anzelon TA, Chowdhury S, Hughes SM, Xiao Y, Lander
GC, MacRae IJ |
(2021) "Structural
basis for piRNA targeting." Nature,
597, 285-289. doi: 10.1038/s41586-021-03856-x.
|
cryo-EM structure of ephydatia fluviatilis
piwia-pirna-target complex . SNAP output
|
|
7l08
|
ribosome |
cryo-EM (3.49 Å) |
Koripella RK, Deep A, Agrawal EK, Keshavan P,
Banavali NK, Agrawal RK |
(2021) "Distinct
mechanisms of the human mitoribosome recycling and
antibiotic resistance." Nat Commun,
12, 3607. doi: 10.1038/s41467-021-23726-4.
|
cryo-EM structure of the human 55s mitoribosome-rrfmt
complex. . SNAP
output
|
|
7l1f
|
viral protein-RNA |
cryo-EM (3.89 Å) |
Bravo JPK, Dangerfield TL, Taylor DW, Johnson KA |
(2021) "Remdesivir
is a delayed translocation inhibitor of SARS-CoV-2
replication." Mol.Cell,
81, 1548-1552.e4. doi: 10.1016/j.molcel.2021.01.035.
|
Sars-cov-2 rdrp in complex with 4 remdesivir
monophosphate . SNAP
output
|
|
7l20
|
ribosome |
cryo-EM (3.15 Å) |
Koripella RK, Deep A, Agrawal EK, Keshavan P,
Banavali NK, Agrawal RK |
(2021) "Distinct
mechanisms of the human mitoribosome recycling and
antibiotic resistance." Nat Commun,
12, 3607. doi: 10.1038/s41467-021-23726-4.
|
cryo-EM structure of the human 39s mitoribosomal
subunit in complex with rrfmt and ef-g2mt. . SNAP output
|
|
7l48
|
RNA binding protein-RNA |
cryo-EM (3.9 Å) |
Xiao R, Li Z, Wang S, Han R, Chang L |
(2021) "Structural
basis for substrate recognition and cleavage by the
dimerization-dependent CRISPR-Cas12f nuclease."
Nucleic Acids Res., 49,
4120-4128. doi: 10.1093/nar/gkab179.
|
cryo-EM structure of a crispr-cas12f binary complex .
SNAP output
|
|
7l6r
|
viral protein-RNA |
X-ray (1.98 Å) |
Minasov G, Rosas-Lemus M, Shuvalova L, Inniss NL,
Brunzelle JS, Daczkowski CM, Hoover P, Mesecar AD,
Satchell KJF |
(2021) "Mn 2+
coordinates Cap-0-RNA to align substrates for efficient
2'- O -methyl transfer by SARS-CoV-2 nsp16."
Sci.Signal., 14. doi:
10.1126/scisignal.abh2071.
|
Crystal structure of sars-cov-2 nsp16-10 heterodimer in
complex with (m7gpppa2m)pupupapapa (cap-1),
s-adenosyl-l-homocysteine (sah) and manganese (mn). .
SNAP output
|
|
7l6t
|
viral protein-RNA |
X-ray (1.78 Å) |
Minasov G, Rosas-Lemus M, Shuvalova L, Inniss NL,
Brunzelle JS, Daczkowski CM, Hoover P, Mesecar AD,
Satchell KJF |
(2021) "Mn 2+
coordinates Cap-0-RNA to align substrates for efficient
2'- O -methyl transfer by SARS-CoV-2 nsp16."
Sci.Signal., 14. doi:
10.1126/scisignal.abh2071.
|
Crystal structure of sars-cov-2 nsp16-10 heterodimer in
complex with (m7gpppa2m)pupupapapa (cap-1),
s-adenosyl-l-homocysteine (sah) and two magnesium (mg)
ions. . SNAP output
|
|
7ld5
|
transferase-RNA |
cryo-EM (3.07 Å) |
Unciuleac MC, Ghosh S, de la Cruz MJ, Goldgur Y,
Shuman S |
(2021) "Structure
and mechanism of Mycobacterium smegmatis polynucleotide
phosphorylase." Rna, 27,
959-969. doi: 10.1261/rna.078822.121.
|
Polynucleotide phosphorylase . SNAP output
|
|
7lh5
|
ribosome |
X-ray (3.27 Å) |
Golkar T, Bassenden AV, Maiti K, Arya DP, Schmeing
TM, Berghuis AM |
(2021) "Structural
basis for plazomicin antibiotic action and
resistance." Commun Biol,
4, 729. doi: 10.1038/s42003-021-02261-4.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with plazomicin, mrna and trnas .
SNAP output
|
|
7lhd
|
virus-RNA |
cryo-EM (4.6 Å) |
Chang JY, Gorzelnik KV, Thongchol J, Zhang J |
(2022) "Structural
Assembly of Q beta Virion and Its Diverse Forms of
Virus-like Particles." Viruses,
14. doi: 10.3390/v14020225.
|
The complete model of phage qbeta virion . SNAP output
|
|
7lj3
|
virus |
cryo-EM (2.9 Å) |
Liu YT, Strugatsky D, Liu W, Zhou ZH |
(2021) "Structure
of human cytomegalovirus virion reveals host tRNA
binding to capsid-associated tegument protein
pp150." Nat Commun, 12,
5513. doi: 10.1038/s41467-021-25791-1.
|
Structure of human transfer RNA visualized in the
cytomegalovirus, a DNA virus . SNAP output
|
|
7ls1
|
ribosome |
cryo-EM (3.3 Å) |
Smith PR, Loerch S, Kunder N, Stanowick AD, Lou TF,
Campbell ZT |
(2021) "Functionally
distinct roles for eEF2K in the control of ribosome
availability and p-body abundance." Nat
Commun, 12, 6789. doi: 10.1038/s41467-021-27160-4.
|
80s ribosome from mouse bound to eef2 (class ii) .
SNAP output
|
|
7ls2
|
ribosome |
cryo-EM (3.1 Å) |
Smith PR, Loerch S, Kunder N, Stanowick AD, Lou TF,
Campbell ZT |
(2021) "Functionally
distinct roles for eEF2K in the control of ribosome
availability and p-body abundance." Nat
Commun, 12, 6789. doi: 10.1038/s41467-021-27160-4.
|
80s ribosome from mouse bound to eef2 (class i) .
SNAP output
|
|
7lv0
|
ribosome |
cryo-EM (3.2 Å) |
Demo G, Gamper HB, Loveland AB, Masuda I, Carbone CE,
Svidritskiy E, Hou YM, Korostelev AA |
(2021) "Structural
basis for +1 ribosomal frameshifting during
EF-G-catalyzed translocation." Nat Commun,
12, 4644. doi: 10.1038/s41467-021-24911-1.
|
Pre-translocation rotated ribosome
+1-frameshifting(ccc-a) complex (structure irot-fs) .
SNAP output
|
|
7lvk
|
ribosome |
cryo-EM (2.2 Å) |
Tsai K, Stojkovic V, Noda-Garcia L, Myasnikov AG,
Young ID, Palla A, Venkataramanan S, Floor S, Fraser JS,
Frost A, Tawfik DS, Fujimori DG |
"Investigating antibiotic resistance of a
ribosomal-RNA methylating enzyme through directed
evolution." |
Cfr-modified 50s subunit from escherichia coli .
SNAP output
|
|
7m2v
|
virus-RNA |
X-ray (1.8 Å) |
McPherson A |
(2021) "Structures
of additional crystal forms of Satellite tobacco mosaic
virus grown from a variety of salts." Acta
Crystallogr.,Sect.F, 77, 473-483.
doi: 10.1107/S2053230X21011547.
|
Crystallographic structure of the rhombohedral crystal
form of stmv grown from chloride . SNAP output
|
|
7m3t
|
virus-RNA |
X-ray (3.2 Å) |
McPherson A |
(2021) "Structures
of additional crystal forms of Satellite tobacco mosaic
virus grown from a variety of salts." Acta
Crystallogr.,Sect.F, 77, 473-483.
doi: 10.1107/S2053230X21011547.
|
Crystallographic structure of a cubic crystal of stmv
(80.7 degree rotation about 111) grown from chloride .
SNAP output
|
|
7m4u
|
ribosome |
cryo-EM (2.71 Å) |
Zhang Z, Morgan CE, Bonomo RA, Yu EW |
(2021) "Cryo-EM
Determination of Eravacycline-Bound Structures of the
Ribosome and the Multidrug Efflux Pump AdeJ of
Acinetobacter baumannii." Mbio,
12, e0103121. doi: 10.1128/mBio.01031-21.
|
A. baumannii ribosome-eravacycline complex: 30s .
SNAP output
|
|
7m4v
|
ribosome |
cryo-EM (2.54 Å) |
Zhang Z, Morgan CE, Bonomo RA, Yu EW |
(2021) "Cryo-EM
Determination of Eravacycline-Bound Structures of the
Ribosome and the Multidrug Efflux Pump AdeJ of
Acinetobacter baumannii." Mbio,
12, e0103121. doi: 10.1128/mBio.01031-21.
|
A. baumannii ribosome-eravacycline complex: 50s .
SNAP output
|
|
7m4w
|
ribosome-antibiotic |
cryo-EM (2.55 Å) |
Zhang Z, Morgan CE, Bonomo RA, Yu EW |
(2021) "Cryo-EM
Determination of Eravacycline-Bound Structures of the
Ribosome and the Multidrug Efflux Pump AdeJ of
Acinetobacter baumannii." Mbio,
12, e0103121. doi: 10.1128/mBio.01031-21.
|
A. baumannii ribosome-eravacycline complex: empty 70s .
SNAP output
|
|
7m4x
|
ribosome-antibiotic |
cryo-EM (2.66 Å) |
Zhang Z, Morgan CE, Bonomo RA, Yu EW |
(2021) "Cryo-EM
Determination of Eravacycline-Bound Structures of the
Ribosome and the Multidrug Efflux Pump AdeJ of
Acinetobacter baumannii." Mbio,
12, e0103121. doi: 10.1128/mBio.01031-21.
|
A. baumannii ribosome-eravacycline complex: p-site trna
70s . SNAP output
|
|
7m4y
|
ribosome |
cryo-EM (2.5 Å) |
Zhang Z, Morgan CE, Bonomo RA, Yu EW |
(2021) "Cryo-EM
Determination of Eravacycline-Bound Structures of the
Ribosome and the Multidrug Efflux Pump AdeJ of
Acinetobacter baumannii." Mbio,
12, e0103121. doi: 10.1128/mBio.01031-21.
|
A. baumannii ribosome-eravacycline complex: e-site trna
70s . SNAP output
|
|
7m4z
|
ribosome |
cryo-EM (2.92 Å) |
Zhang Z, Morgan CE, Bonomo RA, Yu EW |
(2021) "Cryo-EM
Determination of Eravacycline-Bound Structures of the
Ribosome and the Multidrug Efflux Pump AdeJ of
Acinetobacter baumannii." Mbio,
12, e0103121. doi: 10.1128/mBio.01031-21.
|
A. baumannii ribosome-eravacycline complex: hpf-bound
70s . SNAP output
|
|
7m50
|
virus |
X-ray (2.31 Å) |
McPherson A |
(2021) "Structures
of additional crystal forms of Satellite tobacco mosaic
virus grown from a variety of salts." Acta
Crystallogr.,Sect.F, 77, 473-483.
doi: 10.1107/S2053230X21011547.
|
Crystallographic structure of a cubic crystal form of
stmv grown from ammonium sulfate . SNAP output
|
|
7m5d
|
ribosome |
cryo-EM (2.8 Å) |
Zhang J |
"Cryo-EM structure of a non-rotated E.coli 70S
ribosome in complex with RF3-GTP, RF1 and P-tRNA (state
I)." |
cryo-EM structure of a non-rotated e.coli 70s ribosome
in complex with rf3-gtp, rf1 and p-trna (state i) .
SNAP output
|
|
7m5o
|
viral protein-RNA |
cryo-EM (3.54 Å) |
Pausch P, Soczek KM, Herbst DA, Tsuchida CA,
Al-Shayeb B, Banfield JF, Nogales E, Doudna JA |
(2021) "DNA
interference states of the hypercompact CRISPR-Cas Phi
effector." Nat.Struct.Mol.Biol.,
28, 652-661. doi: 10.1038/s41594-021-00632-3.
|
cryo-EM structure of casphi-2 (cas12j) bound to crrna .
SNAP output
|
|
7md7
|
ribosome |
X-ray (2.8 Å) |
Chen CW, Pavlova JA, Lukianov DA, Tereshchenkov AG,
Makarov GI, Khairullina ZZ, Tashlitsky VN, Paleskava A,
Konevega AL, Bogdanov AA, Osterman IA, Sumbatyan NV,
Polikanov YS |
(2021) "Binding
and Action of Triphenylphosphonium Analog of
Chloramphenicol upon the Bacterial Ribosome."
Antibiotics, 10. doi:
10.3390/antibiotics10040390.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with triphenylphosphonium analog of
chloramphenicol cam-c4-tpp and protein y (yfia) at
2.80a resolution . SNAP
output
|
|
7mdl
|
transferase |
X-ray (2.32 Å) |
Puppala AK, Castillo Suchkou J, French RL, Kiernan
KA, Simonovic M |
(2023) "Structural
basis for the tRNA-dependent activation of the terminal
complex of selenocysteine synthesis in humans."
Nucleic Acids Res. doi: 10.1093/nar/gkad182.
|
High-resolution crystal structure of human
sepsecs-trnasec complex . SNAP output
|
|
7mdz
|
ribosome |
cryo-EM (3.2 Å) |
Koga Y, Hoang EM, Park Y, Keszei AFA, Murray J, Shao
S, Liau BB |
(2021) "Discovery
of C13-Aminobenzoyl Cycloheximide Derivatives that
Potently Inhibit Translation Elongation."
J.Am.Chem.Soc., 143,
13473-13477. doi: 10.1021/jacs.1c05146.
|
80s rabbit ribosome stalled with benzamide-chx .
SNAP output
|
|
7mjv
|
transferase-RNA |
X-ray (2.24 Å) |
Esakova OA, Grove TL, Yennawar NH, Arcinas AJ, Wang
B, Krebs C, Almo SC, Booker SJ |
(2021) "Structural
basis for tRNA methylthiolation by the radical SAM
enzyme MiaB." Nature,
597, 566-570. doi: 10.1038/s41586-021-03904-6.
|
Miab in the complex with s-adenosylmethionine and RNA .
SNAP output
|
|
7mjw
|
transferase-RNA |
X-ray (1.4 Å) |
Esakova OA, Grove TL, Yennawar NH, Arcinas AJ, Wang
B, Krebs C, Almo SC, Booker SJ |
(2021) "Structural
basis for tRNA methylthiolation by the radical SAM
enzyme MiaB." Nature,
597, 566-570. doi: 10.1038/s41586-021-03904-6.
|
Methylated miab in the complex with 5'-deoxyadenosine,
methionine and RNA . SNAP output
|
|
7mjx
|
transferase-RNA |
X-ray (1.5 Å) |
Esakova OA, Grove TL, Yennawar NH, Arcinas AJ, Wang
B, Krebs C, Almo SC, Booker SJ |
(2021) "Structural
basis for tRNA methylthiolation by the radical SAM
enzyme MiaB." Nature,
597, 566-570. doi: 10.1038/s41586-021-03904-6.
|
Miab in the complex with 5'-deoxyadenosine, methionine
and RNA . SNAP
output
|
|
7mjy
|
transferase-RNA |
X-ray (1.86 Å) |
Esakova OA, Grove TL, Yennawar NH, Arcinas AJ, Wang
B, Krebs C, Almo SC, Booker SJ |
(2021) "Structural
basis for tRNA methylthiolation by the radical SAM
enzyme MiaB." Nature,
597, 566-570. doi: 10.1038/s41586-021-03904-6.
|
Miab in the complex with s-adenosyl-l-homocysteine and
RNA . SNAP output
|
|
7mlx
|
RNA-immune system |
X-ray (2.09 Å) |
Roman C, Lewicka A, Koirala D, Li NS, Piccirilli
JA |
(2021) "The
SARS-CoV-2 Programmed -1 Ribosomal Frameshifting
Element Crystal Structure Solved to 2.09 angstrom Using
Chaperone-Assisted RNA Crystallography." Acs
Chem.Biol., 16, 1469-1481. doi:
10.1021/acschembio.1c00324.
|
Sars-cov-2 programmed -1 frameshifting element three
stem h-type pseudoknot . SNAP output
|
|
7mpi
|
ribosome |
cryo-EM (3.05 Å) |
Zhao Y, Rai J, Yu H, Li H |
(2022) "CryoEM
structures of pseudouridine-free ribosome suggest
impacts of chemical modifications on ribosome
conformations." Structure,
30, 983. doi: 10.1016/j.str.2022.04.002.
|
Stm1 bound vacant 80s structure isolated from cbf5-d95a
. SNAP output
|
|
7mpj
|
ribosome |
cryo-EM (2.7 Å) |
Zhao Y, Rai J, Yu H, Li H |
(2022) "CryoEM
structures of pseudouridine-free ribosome suggest
impacts of chemical modifications on ribosome
conformations." Structure,
30, 983. doi: 10.1016/j.str.2022.04.002.
|
Stm1 bound vacant 80s structure isolated from wild-type
. SNAP output
|
|
7mpl
|
RNA binding protein-RNA |
X-ray (1.8 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc bound to pgg . SNAP output
|
|
7mpm
|
RNA binding protein-RNA |
X-ray (1.95 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc bound to paa . SNAP output
|
|
7mpn
|
RNA binding protein-RNA |
X-ray (1.94 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc bound to pgc . SNAP output
|
|
7mpq
|
RNA binding protein |
X-ray (2.35 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc cleaving pgg in the presence
of mn2+ . SNAP
output
|
|
7mpu
|
RNA binding protein-RNA |
X-ray (1.72 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Brucella melitensis nrnc bound to pgg . SNAP output
|
|
7mq8
|
ribosome |
cryo-EM (3.6 Å) |
Singh S, Vanden Broeck A, Miller L, Chaker-Margot M,
Klinge S |
(2021) "Nucleolar
maturation of the human small subunit processome."
Science, 373, eabj5338. doi:
10.1126/science.abj5338.
|
cryo-EM structure of the human ssu processome, state
pre-a1 . SNAP output
|
|
7mq9
|
ribosome |
cryo-EM (3.87 Å) |
Singh S, Vanden Broeck A, Miller L, Chaker-Margot M,
Klinge S |
(2021) "Nucleolar
maturation of the human small subunit processome."
Science, 373, eabj5338. doi:
10.1126/science.abj5338.
|
cryo-EM structure of the human ssu processome, state
pre-a1* . SNAP
output
|
|
7mqa
|
ribosome |
cryo-EM (2.7 Å) |
Singh S, Vanden Broeck A, Miller L, Chaker-Margot M,
Klinge S |
(2021) "Nucleolar
maturation of the human small subunit processome."
Science, 373, eabj5338. doi:
10.1126/science.abj5338.
|
cryo-EM structure of the human ssu processome, state
post-a1 . SNAP
output
|
|
7mqb
|
RNA binding protein-RNA |
cryo-EM (3.25 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc bound to pgg. d4 symmetry .
SNAP output
|
|
7mqc
|
RNA binding protein-RNA |
cryo-EM (3.64 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc bound to pgg. c1
reconstruction. . SNAP
output
|
|
7mqd
|
RNA binding protein-RNA |
cryo-EM (3.25 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc complexed with pagg. d4
symmetry. . SNAP
output
|
|
7mqe
|
RNA binding protein-RNA |
cryo-EM (3.69 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc complexed with pagg. c1
reconstruction. . SNAP
output
|
|
7mqf
|
RNA binding protein-RNA |
cryo-EM (2.88 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc complexed with paaagg. d4
symmetry. . SNAP
output
|
|
7mqg
|
RNA binding protein-RNA |
cryo-EM (3.25 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc complexed with paaagg. c1
reconstruction. . SNAP
output
|
|
7mqh
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc complexed with paaagg in the
presence of ca2+. d4 symmetry. . SNAP output
|
|
7mqi
|
RNA binding protein-RNA |
cryo-EM (3.21 Å) |
Lormand JD, Kim SK, Walters-Marrah GA, Brownfield BA,
Fromme JC, Winkler WC, Goodson JR, Lee VT, Sondermann
H |
(2021) "Structural
characterization of NrnC identifies unifying features
of dinucleotidases." Elife,
10. doi: 10.7554/eLife.70146.
|
Bartonella henselae nrnc complexed with paaagg in the
presence of ca2+. c1 reconstruction. . SNAP output
|
|
7mrl
|
viral protein-RNA |
X-ray (3.15 Å) |
Bou-Nader C, Muecksch F, Brown JB, Gordon JM, York A,
Peng C, Ghirlando R, Summers MF, Bieniasz PD, Zhang
J |
(2021) "HIV-1
matrix-tRNA complex structure reveals basis for host
control of Gag localization." Cell Host
Microbe, 29, 1421. doi: 10.1016/j.chom.2021.07.006.
|
Structure of hiv-1 matrix domain bound to human
trnalys3 . SNAP
output
|
|
7msc
|
ribosome |
cryo-EM (2.97 Å) |
Cui Z, Li X, Shin J, Gamper H, Hou YM, Sacchettini
JC, Zhang J |
(2022) "Interplay
between an ATP-binding cassette F protein and the
ribosome from Mycobacterium tuberculosis." Nat
Commun, 13, 432. doi: 10.1038/s41467-022-28078-1.
|
Mtb 70sic in complex with mtbetta at pre_r0 state .
SNAP output
|
|
7msf
|
virus-RNA |
X-ray (2.8 Å) |
Rowsell S, Stonehouse NJ, Convery MA, Adams CJ,
Ellington AD, Hirao I, Peabody DS, Stockley PG, Phillips
SE |
(1998) "Crystal
structures of a series of RNA aptamers complexed to the
same protein target." Nat.Struct.Biol.,
5, 970-975. doi: 10.1038/2946.
|
Ms2 protein capsid-RNA complex . SNAP output
|
|
7msh
|
ribosome |
cryo-EM (3.23 Å) |
Cui Z, Li X, Shin J, Gamper H, Hou YM, Sacchettini
JC, Zhang J |
(2022) "Interplay
between an ATP-binding cassette F protein and the
ribosome from Mycobacterium tuberculosis." Nat
Commun, 13, 432. doi: 10.1038/s41467-022-28078-1.
|
Mtb 70sic in complex with mtbetta at pre_r1 state .
SNAP output
|
|
7msm
|
ribosome |
cryo-EM (2.79 Å) |
Cui Z, Li X, Shin J, Gamper H, Hou YM, Sacchettini
JC, Zhang J |
(2022) "Interplay
between an ATP-binding cassette F protein and the
ribosome from Mycobacterium tuberculosis." Nat
Commun, 13, 432. doi: 10.1038/s41467-022-28078-1.
|
Mtb 70sic in complex with mtbetta at trans_r0 state .
SNAP output
|
|
7msz
|
ribosome |
cryo-EM (3.1 Å) |
Cui Z, Li X, Shin J, Gamper H, Hou YM, Sacchettini
JC, Zhang J |
(2022) "Interplay
between an ATP-binding cassette F protein and the
ribosome from Mycobacterium tuberculosis." Nat
Commun, 13, 432. doi: 10.1038/s41467-022-28078-1.
|
Mtb 70sic in complex with mtbetta at trans_r1 state .
SNAP output
|
|
7mt2
|
ribosome |
cryo-EM (2.76 Å) |
Cui Z, Li X, Shin J, Gamper H, Hou YM, Sacchettini
JC, Zhang J |
(2022) "Interplay
between an ATP-binding cassette F protein and the
ribosome from Mycobacterium tuberculosis." Nat
Commun, 13, 432. doi: 10.1038/s41467-022-28078-1.
|
Mtb 70s initiation complex . SNAP output
|
|
7mt3
|
ribosome |
cryo-EM (2.8 Å) |
Cui Z, Li X, Shin J, Gamper H, Hou YM, Sacchettini
JC, Zhang J |
(2022) "Interplay
between an ATP-binding cassette F protein and the
ribosome from Mycobacterium tuberculosis." Nat
Commun, 13, 432. doi: 10.1038/s41467-022-28078-1.
|
Mtb 70s with p-e trna . SNAP output
|
|
7mt7
|
ribosome |
cryo-EM (2.71 Å) |
Cui Z, Li X, Shin J, Gamper H, Hou YM, Sacchettini
JC, Zhang J |
(2022) "Interplay
between an ATP-binding cassette F protein and the
ribosome from Mycobacterium tuberculosis." Nat
Commun, 13, 432. doi: 10.1038/s41467-022-28078-1.
|
Mtb 70s with p and e site trnas . SNAP output
|
|
7mw8
|
hydrolase |
X-ray (1.9 Å) |
Carozza JA, Cordova AF, Brown JA, AlSaif Y, Bohnert
V, Cao X, Mardjuki RE, Skariah G, Fernandez D, Li L |
(2022) "ENPP1's
regulation of extracellular cGAMP is a ubiquitous
mechanism of attenuating STING signaling."
Proc.Natl.Acad.Sci.USA, 119,
e2119189119. doi: 10.1073/pnas.2119189119.
|
Crystal structure analysis of xac nucleotide
pyrophosphatase-phosphodiesterase . SNAP output
|
|
7n0b
|
viral protein-RNA |
cryo-EM (3.9 Å) |
Liu C, Shi W, Becker ST, Schatz DG, Liu B, Yang
Y |
(2021) "Structural
basis of mismatch recognition by a SARS-CoV-2
proofreading enzyme." Science,
373, 1142-1146. doi: 10.1126/science.abi9310.
|
cryo-EM structure of sars-cov-2 nsp10-nsp14 (wt)-RNA
complex . SNAP
output
|
|
7n0c
|
viral protein-RNA |
cryo-EM (3.4 Å) |
Liu C, Shi W, Becker ST, Schatz DG, Liu B, Yang
Y |
(2021) "Structural
basis of mismatch recognition by a SARS-CoV-2
proofreading enzyme." Science,
373, 1142-1146. doi: 10.1126/science.abi9310.
|
cryo-EM structure of the monomeric form of sars-cov-2
nsp10-nsp14 (e191a)-RNA complex . SNAP output
|
|
7n0d
|
viral protein-RNA |
cryo-EM (2.5 Å) |
Liu C, Shi W, Becker ST, Schatz DG, Liu B, Yang
Y |
(2021) "Structural
basis of mismatch recognition by a SARS-CoV-2
proofreading enzyme." Science,
373, 1142-1146. doi: 10.1126/science.abi9310.
|
cryo-EM structure of the tetrameric form of sars-cov-2
nsp10-nsp14 (e191a)-RNA complex . SNAP output
|
|
7n1p
|
ribosome |
cryo-EM (2.33 Å) |
Rundlet EJ, Holm M, Schacherl M, Natchiar SK, Altman
RB, Spahn CMT, Myasnikov AG, Blanchard SC |
(2021) "Structural
basis of early translocation events on the
ribosome." Nature, 595,
741-745. doi: 10.1038/s41586-021-03713-x.
|
Elongating 70s ribosome complex in a classical
pre-translocation (pre-c) conformation . SNAP output
|
|
7n2c
|
ribosome |
cryo-EM (2.72 Å) |
Rundlet EJ, Holm M, Schacherl M, Natchiar SK, Altman
RB, Spahn CMT, Myasnikov AG, Blanchard SC |
(2021) "Structural
basis of early translocation events on the
ribosome." Nature, 595,
741-745. doi: 10.1038/s41586-021-03713-x.
|
Elongating 70s ribosome complex in a fusidic
acid-stalled intermediate state of translocation bound
to ef-g(gdp) (int2) . SNAP output
|
|
7n2u
|
ribosome |
cryo-EM (2.53 Å) |
Rundlet EJ, Holm M, Schacherl M, Natchiar SK, Altman
RB, Spahn CMT, Myasnikov AG, Blanchard SC |
(2021) "Structural
basis of early translocation events on the
ribosome." Nature, 595,
741-745. doi: 10.1038/s41586-021-03713-x.
|
Elongating 70s ribosome complex in a hybrid-h1
pre-translocation (pre-h1) conformation . SNAP output
|
|
7n2v
|
ribosome |
cryo-EM (2.54 Å) |
Rundlet EJ, Holm M, Schacherl M, Natchiar SK, Altman
RB, Spahn CMT, Myasnikov AG, Blanchard SC |
(2021) "Structural
basis of early translocation events on the
ribosome." Nature, 595,
741-745. doi: 10.1038/s41586-021-03713-x.
|
Elongating 70s ribosome complex in a
spectinomycin-stalled intermediate state of
translocation bound to ef-g in an active, gtp
conformation (int1) . SNAP output
|
|
7n30
|
ribosome |
cryo-EM (2.66 Å) |
Rundlet EJ, Holm M, Schacherl M, Natchiar SK, Altman
RB, Spahn CMT, Myasnikov AG, Blanchard SC |
(2021) "Structural
basis of early translocation events on the
ribosome." Nature, 595,
741-745. doi: 10.1038/s41586-021-03713-x.
|
Elongating 70s ribosome complex in a hybrid-h2*
pre-translocation (pre-h2*) conformation . SNAP output
|
|
7n31
|
ribosome |
cryo-EM (2.69 Å) |
Rundlet EJ, Holm M, Schacherl M, Natchiar SK, Altman
RB, Spahn CMT, Myasnikov AG, Blanchard SC |
(2021) "Structural
basis of early translocation events on the
ribosome." Nature, 595,
741-745. doi: 10.1038/s41586-021-03713-x.
|
Elongating 70s ribosome complex in a post-translocation
(post) conformation . SNAP output
|
|
7n3o
|
RNA binding protein-RNA |
cryo-EM (3.8 Å) |
Xiao R, Wang S, Han R, Li Z, Gabel C, Mukherjee IA,
Chang L |
(2021) "Structural
basis of target DNA recognition by CRISPR-Cas12k for
RNA-guided DNA transposition." Mol.Cell,
81, 4457-4466.e5. doi: 10.1016/j.molcel.2021.07.043.
|
cryo-EM structure of the cas12k-sgrna complex .
SNAP output
|
|
7n8b
|
ribosome |
cryo-EM (3.05 Å) |
Zhao Y, Rai J, Yu H, Li H |
(2022) "CryoEM
structures of pseudouridine-free ribosome suggest
impacts of chemical modifications on ribosome
conformations." Structure,
30, 983. doi: 10.1016/j.str.2022.04.002.
|
Cycloheximide bound vacant 80s structure isolated from
cbf5-d95a . SNAP
output
|
|
7nac
|
ribosome |
cryo-EM (3.04 Å) |
Cruz VE, Sekulski K, Peddada N, Sailer C,
Balasubramanian S, Weirich CS, Stengel F, Erzberger
JP |
(2022) "Sequence-specific
remodeling of a topologically complex RNP substrate by
Spb4." Nat.Struct.Mol.Biol.,
29, 1228-1238. doi: 10.1038/s41594-022-00874-9.
|
State e2 nucleolar 60s ribosomal biogenesis
intermediate - composite model . SNAP output
|
|
7nad
|
ribosome |
cryo-EM (3.04 Å) |
Cruz VE, Sekulski K, Peddada N, Sailer C,
Balasubramanian S, Weirich CS, Stengel F, Erzberger
JP |
(2022) "Sequence-specific
remodeling of a topologically complex RNP substrate by
Spb4." Nat.Struct.Mol.Biol.,
29, 1228-1238. doi: 10.1038/s41594-022-00874-9.
|
State e2 nucleolar 60s ribosomal biogenesis
intermediate - spb4 local refinement model . SNAP output
|
|
7naf
|
ribosome |
cryo-EM (3.13 Å) |
Cruz VE, Sekulski K, Peddada N, Sailer C,
Balasubramanian S, Weirich CS, Stengel F, Erzberger
JP |
(2022) "Sequence-specific
remodeling of a topologically complex RNP substrate by
Spb4." Nat.Struct.Mol.Biol.,
29, 1228-1238. doi: 10.1038/s41594-022-00874-9.
|
State e2 nucleolar 60s ribosomal biogenesis
intermediate - spb1-mtd local model . SNAP output
|
|
7nar
|
ribosome |
cryo-EM (3.0 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Complete bacterial 30s ribosomal subunit assembly
complex state f (+rsga)(consensus refinement) .
SNAP output
|
|
7nas
|
ribosome |
cryo-EM (3.31 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
a (multibody refinement for body domain of 30s
ribosome) . SNAP
output
|
|
7nat
|
ribosome |
cryo-EM (3.59 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
a (consensus refinement) . SNAP output
|
|
7nau
|
ribosome |
cryo-EM (3.78 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
c (consensus refinement) . SNAP output
|
|
7nav
|
ribosome |
cryo-EM (4.8 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Bacterial 30s ribosomal subunit assembly complex state
d (consensus refinement) . SNAP output
|
|
7nax
|
ribosome |
cryo-EM (2.96 Å) |
Schedlbauer A, Iturrioz I, Ochoa-Lizarralde B,
Diercks T, Lopez-Alonso JP, Lavin JL, Kaminishi T, Capuni
R, Dhimole N, de Astigarraga E, Gil-Carton D, Fucini P,
Connell SR |
(2021) "A
conserved rRNA switch is central to decoding site
maturation on the small ribosomal subunit." Sci
Adv, 7. doi: 10.1126/sciadv.abf7547.
|
Complete bacterial 30s ribosomal subunit assembly
complex state i (consensus refinement) . SNAP output
|
|
7nbu
|
toxin |
cryo-EM (3.11 Å) |
Mansour M, Giudice E, Xu X, Akarsu H, Bordes P,
Guillet V, Bigot DJ, Slama N, D'urso G, Chat S, Redder P,
Falquet L, Mourey L, Gillet R, Genevaux P |
(2022) "Substrate
recognition and cryo-EM structure of the ribosome-bound
TAC toxin of Mycobacterium tuberculosis." Nat
Commun, 13, 2641. doi: 10.1038/s41467-022-30373-w.
|
Structure of the higb1 toxin mutant k95a from
mycobacterium tuberculosis (rv1955) and its target, the
cspa mrna, on the e. coli ribosome. . SNAP output
|
|
7ndj
|
RNA binding protein |
X-ray (1.649 Å) |
Garg A, Roske Y, Yamada S, Uehata T, Takeuchi O,
Heinemann U |
(2021) "PIN and
CCCH Zn-finger domains coordinate RNA targeting in
ZC3H12 family endoribonucleases." Nucleic Acids
Res., 49, 5369-5381. doi:
10.1093/nar/gkab316.
|
Crystal structure of zc3h12c pin-ccch zn finger domain
with RNA heptamer . SNAP
output
|
|
7nfx
|
ribosome |
cryo-EM (3.2 Å) |
Lee JH, Jomaa A, Chung S, Hwang Fu YH, Qian R, Sun X,
Hsieh HH, Chandrasekar S, Bi X, Mattei S, Boehringer D,
Weiss S, Ban N, Shan SO |
(2021) "Receptor
compaction and GTPase rearrangement drive SRP-mediated
cotranslational protein translocation into the ER."
Sci Adv, 7. doi: 10.1126/sciadv.abg0942.
|
Mammalian ribosome nascent chain complex with srp and
srp receptor in early state a . SNAP output
|
|
7nga
|
antiviral protein |
cryo-EM (3.9 Å) |
Yu Q, Herrero Del Valle A, Singh R, Modis Y |
(2021) "MDA5
disease variant M854K prevents ATP-dependent structural
discrimination of viral and cellular RNA." Nat
Commun, 12, 6668. doi: 10.1038/s41467-021-27062-5.
|
Cryoem structure of the mda5-dsrna filament in complex
with adp with 88-degree helical twist . SNAP output
|
|
7nha
|
viral protein |
cryo-EM (2.91 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer -
endonuclease and priming loop ordered (class2a) .
SNAP output
|
|
7nhc
|
viral protein |
cryo-EM (2.87 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer -
endonuclease ordered (class2b) . SNAP output
|
|
7nhk
|
ribosome |
cryo-EM (2.9 Å) |
Crowe-McAuliffe C, Murina V, Turnbull KJ, Kasari M,
Mohamad M, Polte C, Takada H, Vaitkevicius K, Johansson
J, Ignatova Z, Atkinson GC, O'Neill AJ, Hauryliuk V,
Wilson DN |
(2021) "Structural
basis of ABCF-mediated resistance to pleuromutilin,
lincosamide, and streptogramin A antibiotics in
Gram-positive pathogens." Nat Commun,
12, 3577. doi: 10.1038/s41467-021-23753-1.
|
Lsaa, an antibiotic resistance abcf, in complex with
70s ribosome from enterococcus faecalis . SNAP output
|
|
7nhl
|
ribosome |
cryo-EM (3.1 Å) |
Crowe-McAuliffe C, Murina V, Turnbull KJ, Kasari M,
Mohamad M, Polte C, Takada H, Vaitkevicius K, Johansson
J, Ignatova Z, Atkinson GC, O'Neill AJ, Hauryliuk V,
Wilson DN |
(2021) "Structural
basis of ABCF-mediated resistance to pleuromutilin,
lincosamide, and streptogramin A antibiotics in
Gram-positive pathogens." Nat Commun,
12, 3577. doi: 10.1038/s41467-021-23753-1.
|
Vgaa-lc, an antibiotic resistance abcf, in complex with
70s ribosome from staphylococcus aureus . SNAP output
|
|
7nhm
|
ribosome |
cryo-EM (3.1 Å) |
Crowe-McAuliffe C, Murina V, Turnbull KJ, Kasari M,
Mohamad M, Polte C, Takada H, Vaitkevicius K, Johansson
J, Ignatova Z, Atkinson GC, O'Neill AJ, Hauryliuk V,
Wilson DN |
(2021) "Structural
basis of ABCF-mediated resistance to pleuromutilin,
lincosamide, and streptogramin A antibiotics in
Gram-positive pathogens." Nat Commun,
12, 3577. doi: 10.1038/s41467-021-23753-1.
|
70s ribosome from staphylococcus aureus . SNAP output
|
|
7nhn
|
ribosome |
cryo-EM (2.9 Å) |
Crowe-McAuliffe C, Murina V, Turnbull KJ, Kasari M,
Mohamad M, Polte C, Takada H, Vaitkevicius K, Johansson
J, Ignatova Z, Atkinson GC, O'Neill AJ, Hauryliuk V,
Wilson DN |
(2021) "Structural
basis of ABCF-mediated resistance to pleuromutilin,
lincosamide, and streptogramin A antibiotics in
Gram-positive pathogens." Nat Commun,
12, 3577. doi: 10.1038/s41467-021-23753-1.
|
Vgal, an antibiotic resistance abcf, in complex with
70s ribosome from listeria monocytogenes . SNAP output
|
|
7nhx
|
viral protein |
cryo-EM (3.23 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer -
full transcriptase (class1) . SNAP output
|
|
7ni0
|
viral protein |
cryo-EM (3.32 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer -
replicase (class 3) . SNAP output
|
|
7nic
|
antiviral protein |
cryo-EM (4.3 Å) |
Yu Q, Herrero Del Valle A, Singh R, Modis Y |
(2021) "MDA5
disease variant M854K prevents ATP-dependent structural
discrimination of viral and cellular RNA." Nat
Commun, 12, 6668. doi: 10.1038/s41467-021-27062-5.
|
Cryoem structure of disease related m854k mda5-dsrna
filament in complex with adp-alf4(minor class) .
SNAP output
|
|
7nik
|
viral protein |
cryo-EM (6.2 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8189 core . SNAP
output
|
|
7nil
|
viral protein |
cryo-EM (5.01 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8190 core . SNAP
output
|
|
7niq
|
antiviral protein |
cryo-EM (4.3 Å) |
Yu Q, Herrero Del Valle A, Singh R, Modis Y |
(2021) "MDA5
disease variant M854K prevents ATP-dependent structural
discrimination of viral and cellular RNA." Nat
Commun, 12, 6668. doi: 10.1038/s41467-021-27062-5.
|
Cryoem structure of disease related m854k mda5-dsrna
filament in complex with adp-alf4(major class) .
SNAP output
|
|
7nir
|
viral protein |
cryo-EM (6.7 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8191 core . SNAP
output
|
|
7nis
|
viral protein |
cryo-EM (5.96 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8192 core . SNAP
output
|
|
7nj3
|
viral protein |
cryo-EM (4.48 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8196 core . SNAP
output
|
|
7nj4
|
viral protein |
cryo-EM (5.84 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8198 core . SNAP
output
|
|
7nj5
|
viral protein |
cryo-EM (4.63 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8199 core . SNAP
output
|
|
7nj7
|
viral protein |
cryo-EM (4.82 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8200 core . SNAP
output
|
|
7njc
|
RNA binding protein |
X-ray (1.38 Å) |
Farhat DC, Bowler MW, Communie G, Pontier D, Belmudes
L, Mas C, Corrao C, Coute Y, Bougdour A, Lagrange T,
Hakimi MA, Swale C |
(2021) "A
plant-like mechanism coupling m6A reading to
polyadenylation safeguards transcriptome integrity and
developmental gene partitioning in Toxoplasma ."
Elife, 10. doi: 10.7554/eLife.68312.
|
Crystal structure of the toxoplasma cpsf4 yth-domain in
complex with a 7 mer m6a-modified RNA . SNAP output
|
|
7nk1
|
viral protein |
cryo-EM (4.22 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 influenza virus polymerase heterotirmer in complex
with vrna promoters and nb8201 . SNAP output
|
|
7nk2
|
viral protein |
cryo-EM (4.84 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8202 core . SNAP
output
|
|
7nk4
|
viral protein |
cryo-EM (5.32 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8203 core . SNAP
output
|
|
7nk6
|
viral protein |
cryo-EM (6.72 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8204 . SNAP output
|
|
7nk8
|
viral protein |
cryo-EM (5.34 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8205 core . SNAP
output
|
|
7nka
|
viral protein |
cryo-EM (4.07 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8206 . SNAP output
|
|
7nkc
|
viral protein |
cryo-EM (4.46 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8207 . SNAP output
|
|
7nki
|
viral protein |
cryo-EM (4.67 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8209 core . SNAP
output
|
|
7nkr
|
viral protein |
cryo-EM (5.6 Å) |
Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Serna
Martin I, Pardon E, Steyaert J, Fodor E, Grimes JM |
(2022) "Mapping
inhibitory sites on the RNA polymerase of the 1918
pandemic influenza virus using nanobodies." Nat
Commun, 13, 251. doi: 10.1038/s41467-021-27950-w.
|
1918 h1n1 viral influenza polymerase heterotrimer with
nb8210 . SNAP output
|
|
7nq4
|
RNA binding protein |
X-ray (2.88 Å) |
Sievers K, Welp L, Urlaub H, Ficner R |
(2021) "Structural
and functional insights into human tRNA guanine
transgylcosylase." Rna Biol.,
18, 382-396. doi: 10.1080/15476286.2021.1950980.
|
Human trna guanine transglycosylase (tgt), RNA-bound
covalent intermediate . SNAP output
|
|
7nqh
|
translation |
cryo-EM (3.5 Å) |
Kummer E, Schubert KN, Schoenhut T, Scaiola A, Ban
N |
(2021) "Structural
basis of translation termination, rescue, and recycling
in mammalian mitochondria." Mol.Cell,
81, 2566-2582.e6. doi: 10.1016/j.molcel.2021.03.042.
|
55s mammalian mitochondrial ribosome with mtrf1a and
p-site trnamet . SNAP
output
|
|
7nql
|
translation |
cryo-EM (3.4 Å) |
Kummer E, Schubert KN, Schoenhut T, Scaiola A, Ban
N |
(2021) "Structural
basis of translation termination, rescue, and recycling
in mammalian mitochondria." Mol.Cell,
81, 2566-2582.e6. doi: 10.1016/j.molcel.2021.03.042.
|
55s mammalian mitochondrial ribosome with ict1 and p
site trnamet . SNAP
output
|
|
7nrc
|
ribosome |
cryo-EM (3.9 Å) |
Pochopien AA, Beckert B, Kasvandik S, Berninghausen
O, Beckmann R, Tenson T, Wilson DN |
(2021) "Structure
of Gcn1 bound to stalled and colliding 80S
ribosomes." Proc.Natl.Acad.Sci.USA,
118. doi: 10.1073/pnas.2022756118.
|
Structure of the yeast gcn1 bound to a leading stalled
80s ribosome with rbg2, gir2, a- and p-trna and eif5a .
SNAP output
|
|
7nrd
|
ribosome |
cryo-EM (4.36 Å) |
Pochopien AA, Beckert B, Kasvandik S, Berninghausen
O, Beckmann R, Tenson T, Wilson DN |
(2021) "Structure
of Gcn1 bound to stalled and colliding 80S
ribosomes." Proc.Natl.Acad.Sci.USA,
118. doi: 10.1073/pnas.2022756118.
|
Structure of the yeast gcn1 bound to a colliding
stalled 80s ribosome with mbf1, a-p-trna and p-e-trna .
SNAP output
|
|
7nsh
|
translation |
cryo-EM (3.2 Å) |
Kummer E, Schubert KN, Schoenhut T, Scaiola A, Ban
N |
(2021) "Structural
basis of translation termination, rescue, and recycling
in mammalian mitochondria." Mol.Cell,
81, 2566-2582.e6. doi: 10.1016/j.molcel.2021.03.042.
|
39s mammalian mitochondrial large ribosomal subunit
with mtrrf (post) and mtefg2 . SNAP output
|
|
7nsi
|
translation |
cryo-EM (4.6 Å) |
Kummer E, Schubert KN, Schoenhut T, Scaiola A, Ban
N |
(2021) "Structural
basis of translation termination, rescue, and recycling
in mammalian mitochondria." Mol.Cell,
81, 2566-2582.e6. doi: 10.1016/j.molcel.2021.03.042.
|
55s mammalian mitochondrial ribosome with mtrrf (pre)
and trna(p-e) . SNAP
output
|
|
7nsj
|
translation |
cryo-EM (3.9 Å) |
Kummer E, Schubert KN, Schoenhut T, Scaiola A, Ban
N |
(2021) "Structural
basis of translation termination, rescue, and recycling
in mammalian mitochondria." Mol.Cell,
81, 2566-2582.e6. doi: 10.1016/j.molcel.2021.03.042.
|
55s mammalian mitochondrial ribosome with trna(p-p) and
trna(e*) . SNAP
output
|
|
7nso
|
ribosome |
cryo-EM (2.9 Å) |
Beckert B, Leroy EC, Sothiselvam S, Bock LV, Svetlov
MS, Graf M, Arenz S, Abdelshahid M, Seip B, Grubmuller H,
Mankin AS, Innis CA, Vazquez-Laslop N, Wilson DN |
(2021) "Structural
and mechanistic basis for translation inhibition by
macrolide and ketolide antibiotics." Nat
Commun, 12, 4466. doi: 10.1038/s41467-021-24674-9.
|
Structure of ermdl-erythromycin-stalled 70s e. coli
ribosomal complex with p-trna . SNAP output
|
|
7nsp
|
ribosome |
cryo-EM (3.5 Å) |
Beckert B, Leroy EC, Sothiselvam S, Bock LV, Svetlov
MS, Graf M, Arenz S, Abdelshahid M, Seip B, Grubmuller H,
Mankin AS, Innis CA, Vazquez-Laslop N, Wilson DN |
(2021) "Structural
and mechanistic basis for translation inhibition by
macrolide and ketolide antibiotics." Nat
Commun, 12, 4466. doi: 10.1038/s41467-021-24674-9.
|
Structure of ermdl-erythromycin-stalled 70s e. coli
ribosomal complex with a and p-trna . SNAP output
|
|
7nsq
|
ribosome |
cryo-EM (3.1 Å) |
Beckert B, Leroy EC, Sothiselvam S, Bock LV, Svetlov
MS, Graf M, Arenz S, Abdelshahid M, Seip B, Grubmuller H,
Mankin AS, Innis CA, Vazquez-Laslop N, Wilson DN |
(2021) "Structural
and mechanistic basis for translation inhibition by
macrolide and ketolide antibiotics." Nat
Commun, 12, 4466. doi: 10.1038/s41467-021-24674-9.
|
Structure of ermdl-telithromycin-stalled 70s e. coli
ribosomal complex with a and p-trna . SNAP output
|
|
7nt5
|
viral protein |
cryo-EM (3.5 Å) |
Ker DS, Jenkins HT, Greive SJ, Antson AA |
(2021) "CryoEM
structure of the Nipah virus nucleocapsid
assembly." Plos Pathog.,
17, e1009740. doi: 10.1371/journal.ppat.1009740.
|
Cryoem structure of the nipah virus nucleocapsid single
helical turn assembly . SNAP output
|
|
7nt6
|
viral protein |
cryo-EM (4.3 Å) |
Ker DS, Jenkins HT, Greive SJ, Antson AA |
(2021) "CryoEM
structure of the Nipah virus nucleocapsid
assembly." Plos Pathog.,
17, e1009740. doi: 10.1371/journal.ppat.1009740.
|
Cryoem structure of the nipah virus nucleocapsid spiral
clam-shaped assembly . SNAP output
|
|
7nun
|
virus |
cryo-EM (3.6 Å) |
Hrebik D, Fuzik T, Gondova M, Smerdova L, Adamopoulos
A, Sedo O, Zdrahal Z, Plevka P |
(2021) "ICAM-1
induced rearrangements of capsid and genome prime
rhinovirus 14 for activation and uncoating."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2024251118.
|
Rhinovirus 14 icam-1 virion-like particle at ph 6.2 .
SNAP output
|
|
7nuq
|
virus |
cryo-EM (2.8 Å) |
Hrebik D, Fuzik T, Gondova M, Smerdova L, Adamopoulos
A, Sedo O, Zdrahal Z, Plevka P |
(2021) "ICAM-1
induced rearrangements of capsid and genome prime
rhinovirus 14 for activation and uncoating."
Proc.Natl.Acad.Sci.USA, 118.
doi: 10.1073/pnas.2024251118.
|
Rhinovirus 14 virion-like at ph 6.2 . SNAP output
|
|
7nwh
|
ribosome |
cryo-EM (4.1 Å) |
Powers KT, Stevenson-Jones F, Yadav SKN, Amthor B,
Bufton JC, Borucu U, Shen D, Becker JP, Lavysh D, Hentze
MW, Kulozik AE, Neu-Yilik G, Schaffitzel C |
(2021) "Blasticidin
S inhibits mammalian translation and enhances
production of protein encoded by nonsense mRNA."
Nucleic Acids Res., 49,
7665-7679. doi: 10.1093/nar/gkab532.
|
Mammalian pre-termination 80s ribosome with erf1 and
erf3 bound by blasticidin s. . SNAP output
|
|
7nwt
|
ribosome |
cryo-EM (2.66 Å) |
Hill CH, Pekarek L, Napthine S, Kibe A, Firth AE,
Graham SC, Caliskan N, Brierley I |
(2021) "Structural and molecular basis for Cardiovirus
2A protein as a viral gene expression switch." Nat
Commun, 12, 7166. doi: 10.1038/s41467-021-27400-7.
|
Initiated 70s ribosome in complex with 2a protein from
encephalomyocarditis virus (emcv) . SNAP output
|
|
7nww
|
ribosome |
cryo-EM (3.05 Å) |
Agirrezabala X, Samatova E, Macher M, Liutkute M,
Maiti M, Gil-Carton D, Novacek J, Valle M, Rodnina
MV |
(2022) "A switch
from alpha-helical to beta-strand conformation during
co-translational protein folding." Embo
J., 41, e109175. doi: 10.15252/embj.2021109175.
|
Cspa-27 cotranslational folding intermediate 1 .
SNAP output
|
|
7o19
|
translation |
cryo-EM (2.9 Å) |
van der Stel AX, Gordon ER, Sengupta A, Martinez AK,
Klepacki D, Perry TN, Herrero Del Valle A, Vazquez-Laslop
N, Sachs MS, Cruz-Vera LR, Innis CA |
(2021) "Structural
basis for the tryptophan sensitivity of TnaC-mediated
ribosome stalling." Nat Commun,
12, 5340. doi: 10.1038/s41467-021-25663-8.
|
cryo-EM structure of an escherichia coli tnac-ribosome
complex stalled in response to l-tryptophan . SNAP output
|
|
7o1a
|
translation |
cryo-EM (2.4 Å) |
van der Stel AX, Gordon ER, Sengupta A, Martinez AK,
Klepacki D, Perry TN, Herrero Del Valle A, Vazquez-Laslop
N, Sachs MS, Cruz-Vera LR, Innis CA |
(2021) "Structural
basis for the tryptophan sensitivity of TnaC-mediated
ribosome stalling." Nat Commun,
12, 5340. doi: 10.1038/s41467-021-25663-8.
|
cryo-EM structure of an escherichia coli
tnac(r23f)-ribosome complex stalled in response to
l-tryptophan . SNAP
output
|
|
7o1c
|
translation |
cryo-EM (2.6 Å) |
van der Stel AX, Gordon ER, Sengupta A, Martinez AK,
Klepacki D, Perry TN, Herrero Del Valle A, Vazquez-Laslop
N, Sachs MS, Cruz-Vera LR, Innis CA |
(2021) "Structural
basis for the tryptophan sensitivity of TnaC-mediated
ribosome stalling." Nat Commun,
12, 5340. doi: 10.1038/s41467-021-25663-8.
|
cryo-EM structure of an escherichia coli
tnac(r23f)-ribosome-rf2 complex stalled in response to
l-tryptophan . SNAP
output
|
|
7o5b
|
ribosome |
cryo-EM (3.33 Å) |
Czech L, Mais CN, Kratzat H, Sarmah P, Giammarinaro
P, Freibert SA, Esser HF, Musial J, Berninghausen O,
Steinchen W, Beckmann R, Koch HG, Bange G |
(2022) "Inhibition
of SRP-dependent protein secretion by the bacterial
alarmone (p)ppGpp." Nat Commun,
13, 1069. doi: 10.1038/s41467-022-28675-0.
|
cryo-EM structure of a bacillus subtilis mifm-stalled
ribosome-nascent chain complex with (p)ppgpp-srp bound
. SNAP output
|
|
7o5h
|
ribosome |
cryo-EM (3.1 Å) |
Stephan NC, Ries AB, Boehringer D, Ban N |
(2021) "Structural
basis of successive adenosine modifications by the
conserved ribosomal methyltransferase KsgA."
Nucleic Acids Res., 49,
6389-6398. doi: 10.1093/nar/gkab430.
|
Ribosomal methyltransferase ksga bound to small
ribosomal subunit . SNAP
output
|
|
7o7z
|
ribosome |
cryo-EM (2.4 Å) |
Bhatt PR, Scaiola A, Loughran G, Leibundgut M,
Kratzel A, Meurs R, Dreos R, O'Connor KM, McMillan A,
Bode JW, Thiel V, Gatfield D, Atkins JF, Ban N |
(2021) "Structural
basis of ribosomal frameshifting during translation of
the SARS-CoV-2 RNA genome." Science,
372, 1306-1313. doi: 10.1126/science.abf3546.
|
Rabbit 80s ribosome stalled close to the mutated
sars-cov-2 slippery site by a pseudoknot (classified
for pseudoknot) . SNAP
output
|
|
7o80
|
ribosome |
cryo-EM (2.9 Å) |
Bhatt PR, Scaiola A, Loughran G, Leibundgut M,
Kratzel A, Meurs R, Dreos R, O'Connor KM, McMillan A,
Bode JW, Thiel V, Gatfield D, Atkins JF, Ban N |
(2021) "Structural
basis of ribosomal frameshifting during translation of
the SARS-CoV-2 RNA genome." Science,
372, 1306-1313. doi: 10.1126/science.abf3546.
|
Rabbit 80s ribosome in complex with erf1 and abce1
stalled at the stop codon in the mutated sars-cov-2
slippery site . SNAP
output
|
|
7o81
|
ribosome |
cryo-EM (3.1 Å) |
Bhatt PR, Scaiola A, Loughran G, Leibundgut M,
Kratzel A, Meurs R, Dreos R, O'Connor KM, McMillan A,
Bode JW, Thiel V, Gatfield D, Atkins JF, Ban N |
(2021) "Structural
basis of ribosomal frameshifting during translation of
the SARS-CoV-2 RNA genome." Science,
372, 1306-1313. doi: 10.1126/science.abf3546.
|
Rabbit 80s ribosome colliding in another ribosome
stalled by the sars-cov-2 pseudoknot . SNAP output
|
|
7o9k
|
ribosome |
cryo-EM (3.1 Å) |
Cipullo M, Gese GV, Khawaja A, Hallberg BM, Rorbach
J |
(2021) "Structural
basis for late maturation steps of the human
mitoribosomal large subunit." Nat Commun,
12, 3673. doi: 10.1038/s41467-021-23617-8.
|
Human mitochondrial ribosome large subunit assembly
intermediate with mterf4-nsun4, mrm2, mtg1, the malsu
module, gtpbp5 and mtef-tu . SNAP output
|
|
7o9m
|
ribosome |
cryo-EM (2.6 Å) |
Cipullo M, Gese GV, Khawaja A, Hallberg BM, Rorbach
J |
(2021) "Structural
basis for late maturation steps of the human
mitoribosomal large subunit." Nat Commun,
12, 3673. doi: 10.1038/s41467-021-23617-8.
|
Human mitochondrial ribosome large subunit assembly
intermediate with mterf4-nsun4, mrm2, mtg1 and the
malsu module . SNAP
output
|
|
7obq
|
RNA binding protein |
cryo-EM (3.9 Å) |
Jomaa A, Eitzinger S, Zhu Z, Chandrasekar S,
Kobayashi K, Shan SO, Ban N |
(2021) "Molecular
mechanism of cargo recognition and handover by the
mammalian signal recognition particle." Cell
Rep, 36, 109350. doi: 10.1016/j.celrep.2021.109350.
|
Srp-sr at the distal site conformation . SNAP output
|
|
7obr
|
RNA binding protein |
cryo-EM (2.8 Å) |
Jomaa A, Eitzinger S, Zhu Z, Chandrasekar S,
Kobayashi K, Shan SO, Ban N |
(2021) "Molecular
mechanism of cargo recognition and handover by the
mammalian signal recognition particle." Cell
Rep, 36, 109350. doi: 10.1016/j.celrep.2021.109350.
|
Rnc-srp early complex . SNAP output
|
|
7ode
|
ribosome |
cryo-EM (2.84 Å) |
Larsson DSD, Kanchugal P S, Selmer M |
(2022) "Structural
Consequences of Deproteinating the 50S Ribosome."
Biomolecules, 12. doi:
10.3390/biom12111605.
|
E. coli 50s ribosome licl core particle . SNAP output
|
|
7odr
|
ribosome |
cryo-EM (2.9 Å) |
Lenarcic T, Jaskolowski M, Leibundgut M, Scaiola A,
Schonhut T, Saurer M, Lee RG, Rackham O, Filipovska A,
Ban N |
(2021) "Stepwise
maturation of the peptidyl transferase region of human
mitoribosomes." Nat Commun,
12, 3671. doi: 10.1038/s41467-021-23811-8.
|
State a of the human mitoribosomal large subunit
assembly intermediate . SNAP output
|
|
7ods
|
ribosome |
cryo-EM (3.1 Å) |
Lenarcic T, Jaskolowski M, Leibundgut M, Scaiola A,
Schonhut T, Saurer M, Lee RG, Rackham O, Filipovska A,
Ban N |
(2021) "Stepwise
maturation of the peptidyl transferase region of human
mitoribosomes." Nat Commun,
12, 3671. doi: 10.1038/s41467-021-23811-8.
|
State b of the human mitoribosomal large subunit
assembly intermediate . SNAP output
|
|
7odt
|
ribosome |
cryo-EM (3.1 Å) |
Lenarcic T, Jaskolowski M, Leibundgut M, Scaiola A,
Schonhut T, Saurer M, Lee RG, Rackham O, Filipovska A,
Ban N |
(2021) "Stepwise
maturation of the peptidyl transferase region of human
mitoribosomes." Nat Commun,
12, 3671. doi: 10.1038/s41467-021-23811-8.
|
State c of the human mitoribosomal large subunit
assembly intermediate . SNAP output
|
|
7oe0
|
ribosome |
cryo-EM (2.69 Å) |
Maksimova EM, Korepanov AP, Kravchenko OV,
Baymukhametov TN, Myasnikov AG, Vassilenko KS, Afonina
ZA, Stolboushkina EA |
(2021) "RbfA Is
Involved in Two Important Stages of 30S Subunit
Assembly: Formation of the Central Pseudoknot and
Docking of Helix 44 to the Decoding Center."
Int J Mol Sci, 22. doi:
10.3390/ijms22116140.
|
E. coli pre-30s delta rbfa ribosomal subunit class f .
SNAP output
|
|
7oe1
|
ribosome |
cryo-EM (3.05 Å) |
Maksimova EM, Korepanov AP, Kravchenko OV,
Baymukhametov TN, Myasnikov AG, Vassilenko KS, Afonina
ZA, Stolboushkina EA |
(2021) "RbfA Is
Involved in Two Important Stages of 30S Subunit
Assembly: Formation of the Central Pseudoknot and
Docking of Helix 44 to the Decoding Center."
Int J Mol Sci, 22. doi:
10.3390/ijms22116140.
|
30s ribosomal subunit from e. coli . SNAP output
|
|
7oea
|
viral protein |
cryo-EM (2.7 Å) |
Kouba T, Vogel D, Thorkelsson SR, Quemin ERJ,
Williams HM, Milewski M, Busch C, Gunther S, Grunewald K,
Rosenthal M, Cusack S |
(2021) "Conformational
changes in Lassa virus L protein associated with
promoter binding and RNA synthesis activity."
Nat Commun, 12, 7018. doi:
10.1038/s41467-021-27305-5.
|
Lassa virus l protein bound to 3' promoter RNA
(well-resolved polymerase core) [3end-core] . SNAP output
|
|
7oeb
|
viral protein |
cryo-EM (3.04 Å) |
Kouba T, Vogel D, Thorkelsson SR, Quemin ERJ,
Williams HM, Milewski M, Busch C, Gunther S, Grunewald K,
Rosenthal M, Cusack S |
(2021) "Conformational
changes in Lassa virus L protein associated with
promoter binding and RNA synthesis activity."
Nat Commun, 12, 7018. doi:
10.1038/s41467-021-27305-5.
|
Lassa virus l protein bound to 3' promoter RNA
(well-resolved endonuclease) [3end-endo] . SNAP output
|
|
7of0
|
ribosome |
cryo-EM (2.2 Å) |
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E,
Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein
R |
(2021) "Structural
basis of GTPase-mediated mitochondrial ribosome
biogenesis and recycling." Nat Commun,
12, 3672. doi: 10.1038/s41467-021-23702-y.
|
Structure of a human mitochondrial ribosome large
subunit assembly intermediate in complex with
mterf4-nsun4 (dataset1). . SNAP output
|
|
7of1
|
ribosome |
cryo-EM (3.1 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particle
population a from s. cerevisiae . SNAP output
|
|
7of2
|
ribosome |
cryo-EM (2.7 Å) |
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E,
Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein
R |
(2021) "Structural
basis of GTPase-mediated mitochondrial ribosome
biogenesis and recycling." Nat Commun,
12, 3672. doi: 10.1038/s41467-021-23702-y.
|
Structure of a human mitochondrial ribosome large
subunit assembly intermediate in complex with gtpbp6. .
SNAP output
|
|
7of3
|
ribosome |
cryo-EM (2.7 Å) |
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E,
Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein
R |
(2021) "Structural
basis of GTPase-mediated mitochondrial ribosome
biogenesis and recycling." Nat Commun,
12, 3672. doi: 10.1038/s41467-021-23702-y.
|
Structure of a human mitochondrial ribosome large
subunit assembly intermediate in complex with
mterf4-nsun4 (dataset2). . SNAP output
|
|
7of4
|
ribosome |
cryo-EM (2.7 Å) |
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E,
Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein
R |
(2021) "Structural
basis of GTPase-mediated mitochondrial ribosome
biogenesis and recycling." Nat Commun,
12, 3672. doi: 10.1038/s41467-021-23702-y.
|
Structure of mature human mitochondrial ribosome large
subunit in complex with gtpbp6 (ptc conformation 1). .
SNAP output
|
|
7of5
|
ribosome |
cryo-EM (2.9 Å) |
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E,
Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein
R |
(2021) "Structural
basis of GTPase-mediated mitochondrial ribosome
biogenesis and recycling." Nat Commun,
12, 3672. doi: 10.1038/s41467-021-23702-y.
|
Structure of a human mitochondrial ribosome large
subunit assembly intermediate in complex with
mterf4-nsun4 and gtpbp5 (dataset2). . SNAP output
|
|
7of6
|
ribosome |
cryo-EM (2.6 Å) |
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E,
Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein
R |
(2021) "Structural
basis of GTPase-mediated mitochondrial ribosome
biogenesis and recycling." Nat Commun,
12, 3672. doi: 10.1038/s41467-021-23702-y.
|
Structure of mature human mitochondrial ribosome large
subunit in complex with gtpbp6 (ptc conformation 2). .
SNAP output
|
|
7of7
|
ribosome |
cryo-EM (2.5 Å) |
Hillen HS, Lavdovskaia E, Nadler F, Hanitsch E,
Linden A, Bohnsack KE, Urlaub H, Richter-Dennerlein
R |
(2021) "Structural
basis of GTPase-mediated mitochondrial ribosome
biogenesis and recycling." Nat Commun,
12, 3672. doi: 10.1038/s41467-021-23702-y.
|
Structure of a human mitochondrial ribosome large
subunit assembly intermediate in complex with
mterf4-nsun4 and gtpbp5 (dataset1). . SNAP output
|
|
7ofw
|
peptide binding protein |
X-ray (3.15 Å) |
Lukacik P, Owen CD, Harris G, Bolla JR, Picaud S,
Alibay I, Nettleship JE, Bird LE, Owens RJ, Biggin PC,
Filippakopoulos P, Robinson CV, Walsh MA |
(2021) "The
structure of nontypeable Haemophilus influenzae SapA in
a closed conformation reveals a constricted
ligand-binding cavity and a novel RNA binding
motif." Plos One, 16,
e0256070. doi: 10.1371/journal.pone.0256070.
|
Nontypeable haemophillus influenzae sapa in complex
with heme . SNAP
output
|
|
7ofz
|
peptide binding protein |
X-ray (2.62 Å) |
Lukacik P, Owen CD, Harris G, Bolla JR, Picaud S,
Alibay I, Nettleship JE, Bird LE, Owens RJ, Biggin PC,
Filippakopoulos P, Robinson CV, Walsh MA |
(2021) "The
structure of nontypeable Haemophilus influenzae SapA in
a closed conformation reveals a constricted
ligand-binding cavity and a novel RNA binding
motif." Plos One, 16,
e0256070. doi: 10.1371/journal.pone.0256070.
|
Nontypeable haemophillus influenzae sapa in complex
with double stranded RNA . SNAP output
|
|
7og0
|
peptide binding protein |
X-ray (2.61 Å) |
Lukacik P, Owen CD, Harris G, Bolla JR, Picaud S,
Alibay I, Nettleship JE, Bird LE, Owens RJ, Biggin PC,
Filippakopoulos P, Robinson CV, Walsh MA |
(2021) "The
structure of nontypeable Haemophilus influenzae SapA in
a closed conformation reveals a constricted
ligand-binding cavity and a novel RNA binding
motif." Plos One, 16,
e0256070. doi: 10.1371/journal.pone.0256070.
|
Nontypeable haemophillus influenzae sapa in open and
closed conformations, in complex with double stranded
RNA . SNAP output
|
|
7og4
|
translation |
cryo-EM (3.8 Å) |
Aibara S, Singh V, Modelska A, Amunts A |
(2020) "Structural
basis of mitochondrial translation."
Elife, 9. doi: 10.7554/eLife.58362.
|
Human mitochondrial ribosome in complex with p-e-trna .
SNAP output
|
|
7og6
|
virus like particle |
cryo-EM (3.3 Å) |
Thuenemann EC, Byrne MJ, Peyret H, Saunders K,
Castells-Graells R, Ferriol I, Santoni M, Steele JFC,
Ranson NA, Avesani L, Lopez-Moya JJ, Lomonossoff GP |
(2021) "A
Replicating Viral Vector Greatly Enhances Accumulation
of Helical Virus-Like Particles in Plants."
Viruses, 13. doi: 10.3390/v13050885.
|
Structure of alternanthera mosaic vlp by cryoem .
SNAP output
|
|
7ogk
|
RNA binding protein |
cryo-EM (3.4 Å) |
Dendooven T, Sinha D, Roeselova A, Cameron TA, De Lay
NR, Luisi BF, Bandyra KJ |
(2021) "A
cooperative PNPase-Hfq-RNA carrier complex facilitates
bacterial riboregulation." Mol.Cell,
81, 2901. doi: 10.1016/j.molcel.2021.05.032.
|
A cooperative pnpase-hfq-RNA carrier complex
facilitates bacterial riboregulation.
pnpase-3'ets(leuz) . SNAP output
|
|
7ogm
|
RNA binding protein |
cryo-EM (3.7 Å) |
Dendooven T, Sinha D, Roeselova A, Cameron TA, De Lay
NR, Luisi BF, Bandyra KJ |
(2021) "A
cooperative PNPase-Hfq-RNA carrier complex facilitates
bacterial riboregulation." Mol.Cell,
81, 2901. doi: 10.1016/j.molcel.2021.05.032.
|
A cooperative pnpase-hfq-RNA carrier complex
facilitates bacterial riboregulation.
pnpase-3'ets(leuz)-hfq . SNAP output
|
|
7oh3
|
ribosome |
cryo-EM (3.4 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particle
population b from s. cerevisiae . SNAP output
|
|
7ohp
|
ribosome |
cryo-EM (3.9 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particles from
s. cerevisiae after rpl25 expression shut down,
population a . SNAP
output
|
|
7ohq
|
ribosome |
cryo-EM (3.1 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particle
population c from s. cerevisiae . SNAP output
|
|
7ohr
|
ribosome |
cryo-EM (4.72 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particle
population e from s. cerevisiae . SNAP output
|
|
7ohs
|
ribosome |
cryo-EM (4.38 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particle
population f from s. cerevisiae . SNAP output
|
|
7oht
|
ribosome |
cryo-EM (4.7 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particles from
s. cerevisiae after rpl2 expression shut down,
population a . SNAP
output
|
|
7ohu
|
ribosome |
cryo-EM (3.7 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particles from
s. cerevisiae after rpl2 expression shut down,
population b . SNAP
output
|
|
7ohv
|
ribosome |
cryo-EM (3.9 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particles from
s. cerevisiae after rpl2 expression shut down,
population c . SNAP
output
|
|
7ohw
|
ribosome |
cryo-EM (3.5 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particles from
s. cerevisiae after rpl25 expression shut down,
population b . SNAP
output
|
|
7ohx
|
ribosome |
cryo-EM (3.3 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particles from
s. cerevisiae after rpl34 expression shut down,
population a . SNAP
output
|
|
7ohy
|
ribosome |
cryo-EM (3.9 Å) |
Poll G, Pilsl M, Griesenbeck J, Tschochner H,
Milkereit P |
(2021) "Analysis
of subunit folding contribution of three yeast large
ribosomal subunit proteins required for stabilisation
and processing of intermediate nuclear rRNA
precursors." Plos One,
16, e0252497. doi: 10.1371/journal.pone.0252497.
|
Nog1-tap associated immature ribosomal particles from
s. cerevisiae after rpl34 expression shut down,
population b . SNAP
output
|
|
7oi0
|
ribosome |
cryo-EM (2.76 Å) |
Maksimova EM, Korepanov AP, Kravchenko OV,
Baymukhametov TN, Myasnikov AG, Vassilenko KS, Afonina
ZA, Stolboushkina EA |
(2021) "RbfA Is
Involved in Two Important Stages of 30S Subunit
Assembly: Formation of the Central Pseudoknot and
Docking of Helix 44 to the Decoding Center."
Int J Mol Sci, 22. doi:
10.3390/ijms22116140.
|
E.coli delta rbfa pre-30s ribosomal subunit class d .
SNAP output
|
|
7oi3
|
viral protein |
cryo-EM (4.0 Å) |
Zinzula L, Beck F, Klumpe S, Bohn S, Pfeifer G,
Bollschweiler D, Nagy I, Plitzko JM, Baumeister W |
(2021) "Cryo-EM
structure of the cetacean morbillivirus
nucleoprotein-RNA complex."
J.Struct.Biol., 213, 107750.
doi: 10.1016/j.jsb.2021.107750.
|
cryo-EM structure of the cetacean morbillivirus
nucleoprotein-RNA complex . SNAP output
|
|
7oi6
|
ribosome |
cryo-EM (5.7 Å) |
Cheng J, Berninghausen O, Beckmann R |
(2021) "A
distinct assembly pathway of the human 39S late
pre-mitoribosome." Nat Commun,
12, 4544. doi: 10.1038/s41467-021-24818-x.
|
cryo-EM structure of late human 39s mitoribosome
assembly intermediates, state 1 . SNAP output
|
|
7oi7
|
ribosome |
cryo-EM (3.5 Å) |
Cheng J, Berninghausen O, Beckmann R |
(2021) "A
distinct assembly pathway of the human 39S late
pre-mitoribosome." Nat Commun,
12, 4544. doi: 10.1038/s41467-021-24818-x.
|
cryo-EM structure of late human 39s mitoribosome
assembly intermediates, state 2 . SNAP output
|
|
7oi8
|
ribosome |
cryo-EM (3.5 Å) |
Cheng J, Berninghausen O, Beckmann R |
(2021) "A
distinct assembly pathway of the human 39S late
pre-mitoribosome." Nat Commun,
12, 4544. doi: 10.1038/s41467-021-24818-x.
|
cryo-EM structure of late human 39s mitoribosome
assembly intermediates, state 3a . SNAP output
|
|
7oi9
|
ribosome |
cryo-EM (3.3 Å) |
Cheng J, Berninghausen O, Beckmann R |
(2021) "A
distinct assembly pathway of the human 39S late
pre-mitoribosome." Nat Commun,
12, 4544. doi: 10.1038/s41467-021-24818-x.
|
cryo-EM structure of late human 39s mitoribosome
assembly intermediates, state 3b . SNAP output
|
|
7oia
|
ribosome |
cryo-EM (3.2 Å) |
Cheng J, Berninghausen O, Beckmann R |
(2021) "A
distinct assembly pathway of the human 39S late
pre-mitoribosome." Nat Commun,
12, 4544. doi: 10.1038/s41467-021-24818-x.
|
cryo-EM structure of late human 39s mitoribosome
assembly intermediates, state 3c . SNAP output
|
|
7oib
|
ribosome |
cryo-EM (3.3 Å) |
Cheng J, Berninghausen O, Beckmann R |
(2021) "A
distinct assembly pathway of the human 39S late
pre-mitoribosome." Nat Commun,
12, 4544. doi: 10.1038/s41467-021-24818-x.
|
cryo-EM structure of late human 39s mitoribosome
assembly intermediates, state 3d . SNAP output
|
|
7oic
|
ribosome |
cryo-EM (3.1 Å) |
Cheng J, Berninghausen O, Beckmann R |
(2021) "A
distinct assembly pathway of the human 39S late
pre-mitoribosome." Nat Commun,
12, 4544. doi: 10.1038/s41467-021-24818-x.
|
cryo-EM structure of late human 39s mitoribosome
assembly intermediates, state 4 . SNAP output
|
|
7oid
|
ribosome |
cryo-EM (3.7 Å) |
Cheng J, Berninghausen O, Beckmann R |
(2021) "A
distinct assembly pathway of the human 39S late
pre-mitoribosome." Nat Commun,
12, 4544. doi: 10.1038/s41467-021-24818-x.
|
cryo-EM structure of late human 39s mitoribosome
assembly intermediates, state 5a . SNAP output
|
|
7oie
|
ribosome |
cryo-EM (3.5 Å) |
Cheng J, Berninghausen O, Beckmann R |
(2021) "A
distinct assembly pathway of the human 39S late
pre-mitoribosome." Nat Commun,
12, 4544. doi: 10.1038/s41467-021-24818-x.
|
cryo-EM structure of late human 39s mitoribosome
assembly intermediates, state 5b . SNAP output
|
|
7oif
|
ribosome |
cryo-EM (3.0 Å) |
Agirrezabala X, Samatova E, Macher M, Liutkute M,
Maiti M, Gil-Carton D, Novacek J, Valle M, Rodnina
MV |
(2022) "A switch
from alpha-helical to beta-strand conformation during
co-translational protein folding." Embo
J., 41, e109175. doi: 10.15252/embj.2021109175.
|
Cspa-27 cotranslational folding intermediate 2 .
SNAP output
|
|
7oig
|
ribosome |
cryo-EM (3.2 Å) |
Agirrezabala X, Samatova E, Macher M, Liutkute M,
Maiti M, Gil-Carton D, Novacek J, Valle M, Rodnina
MV |
(2022) "A switch
from alpha-helical to beta-strand conformation during
co-translational protein folding." Embo
J., 41, e109175. doi: 10.15252/embj.2021109175.
|
Cspa-27 cotranslational folding intermediate 3 .
SNAP output
|
|
7oii
|
ribosome |
cryo-EM (3.0 Å) |
Agirrezabala X, Samatova E, Macher M, Liutkute M,
Maiti M, Gil-Carton D, Novacek J, Valle M, Rodnina
MV |
(2022) "A switch
from alpha-helical to beta-strand conformation during
co-translational protein folding." Embo
J., 41, e109175. doi: 10.15252/embj.2021109175.
|
Cspa-70 cotranslational folding intermediate 2 .
SNAP output
|
|
7oiz
|
ribosome |
cryo-EM (2.9 Å) |
Su T, Kudva R, Becker T, Buschauer R, Komar T,
Berninghausen O, von Heijne G, Cheng J, Beckmann R |
(2021) "Structural
basis of l-tryptophan-dependent inhibition of release
factor 2 by the TnaC arrest peptide." Nucleic
Acids Res., 49, 9539-9547. doi:
10.1093/nar/gkab665.
|
cryo-EM structure of 70s ribosome stalled with tnac
peptide . SNAP
output
|
|
7oj0
|
ribosome |
cryo-EM (3.5 Å) |
Su T, Kudva R, Becker T, Buschauer R, Komar T,
Berninghausen O, von Heijne G, Cheng J, Beckmann R |
(2021) "Structural
basis of l-tryptophan-dependent inhibition of release
factor 2 by the TnaC arrest peptide." Nucleic
Acids Res., 49, 9539-9547. doi:
10.1093/nar/gkab665.
|
cryo-EM structure of 70s ribosome stalled with tnac
peptide and rf2 . SNAP
output
|
|
7ojk
|
viral protein |
cryo-EM (3.89 Å) |
Kouba T, Vogel D, Thorkelsson SR, Quemin ERJ,
Williams HM, Milewski M, Busch C, Gunther S, Grunewald K,
Rosenthal M, Cusack S |
(2021) "Conformational
changes in Lassa virus L protein associated with
promoter binding and RNA synthesis activity."
Nat Commun, 12, 7018. doi:
10.1038/s41467-021-27305-5.
|
Lassa virus l protein bound to the distal promoter
duplex [distal-promoter] . SNAP output
|
|
7ojl
|
viral protein |
cryo-EM (3.3 Å) |
Kouba T, Vogel D, Thorkelsson SR, Quemin ERJ,
Williams HM, Milewski M, Busch C, Gunther S, Grunewald K,
Rosenthal M, Cusack S |
(2021) "Conformational
changes in Lassa virus L protein associated with
promoter binding and RNA synthesis activity."
Nat Commun, 12, 7018. doi:
10.1038/s41467-021-27305-5.
|
Lassa virus l protein in a pre-initiation conformation
[preinitiation] . SNAP
output
|
|
7ojn
|
viral protein |
cryo-EM (2.92 Å) |
Kouba T, Vogel D, Thorkelsson SR, Quemin ERJ,
Williams HM, Milewski M, Busch C, Gunther S, Grunewald K,
Rosenthal M, Cusack S |
(2021) "Conformational
changes in Lassa virus L protein associated with
promoter binding and RNA synthesis activity."
Nat Commun, 12, 7018. doi:
10.1038/s41467-021-27305-5.
|
Lassa virus l protein in an elongation conformation
[elongation] . SNAP
output
|
|
7olc
|
ribosome |
cryo-EM (2.9 Å) |
Kisonaite M, Wild K, Lapouge K, Ruppert T, Sinning
I |
(2022) "High-resolution
structures of a thermophilic eukaryotic 80S ribosome
reveal atomistic details of translocation." Nat
Commun, 13, 476. doi: 10.1038/s41467-022-27967-9.
|
Thermophilic eukaryotic 80s ribosome at idle post state
. SNAP output
|
|
7old
|
ribosome |
cryo-EM (3.0 Å) |
Kisonaite M, Wild K, Lapouge K, Ruppert T, Sinning
I |
(2022) "High-resolution
structures of a thermophilic eukaryotic 80S ribosome
reveal atomistic details of translocation." Nat
Commun, 13, 476. doi: 10.1038/s41467-022-27967-9.
|
Thermophilic eukaryotic 80s ribosome at pe-e (ti)-post
state . SNAP output
|
|
7om6
|
viral protein |
X-ray (2.18 Å) |
Ferrero DS, Falqui M, Verdaguer N |
(2021) "Snapshots
of a Non-Canonical RdRP in Action."
Viruses, 13. doi: 10.3390/v13071260.
|
Thosea asigna virus rdrp domain in complex with RNA .
SNAP output
|
|
7om7
|
viral protein |
X-ray (2.4 Å) |
Ferrero DS, Falqui M, Verdaguer N |
(2021) "Snapshots
of a Non-Canonical RdRP in Action."
Viruses, 13. doi: 10.3390/v13071260.
|
Thosea asigna virus rdrp domain in complex with RNA and
nucleotide umpnpp . SNAP
output
|
|
7oma
|
viral protein |
X-ray (3.1 Å) |
Ferrero DS, Falqui M, Verdaguer N |
(2021) "Snapshots
of a Non-Canonical RdRP in Action."
Viruses, 13. doi: 10.3390/v13071260.
|
Thosea asigna virus rdrp domain elongation complex .
SNAP output
|
|
7onb
|
splicing |
cryo-EM (3.1 Å) |
Cretu C, Gee P, Liu X, Agrawal A, Nguyen TV, Ghosh
AK, Cook A, Jurica M, Larsen NA, Pena V |
(2021) "Structural
basis of intron selection by U2 snRNP in the presence
of covalent inhibitors." Nat Commun,
12, 4491. doi: 10.1038/s41467-021-24741-1.
|
Structure of the u2 5' module of the a3'-ssa complex .
SNAP output
|
|
7onu
|
RNA binding protein |
cryo-EM (3.0 Å) |
Bhatta A, Dienemann C, Cramer P, Hillen HS |
(2021) "Structural
basis of RNA processing by human mitochondrial RNase
P." Nat.Struct.Mol.Biol.,
28, 713-723. doi: 10.1038/s41594-021-00637-y.
|
Structure of human mitochondrial rnase p in complex
with mitochondrial pre-trna-tyr . SNAP output
|
|
7ooc
|
ribosome |
cryo-EM (3.7 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
Mycoplasma pneumoniae 30s subunit of ribosomes in
chloramphenicol-treated cells . SNAP output
|
|
7ood
|
ribosome |
cryo-EM (3.4 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
Mycoplasma pneumoniae 50s subunit of ribosomes in
chloramphenicol-treated cells . SNAP output
|
|
7ope
|
ribosome |
cryo-EM (3.2 Å) |
Takada H, Crowe-McAuliffe C, Polte C, Sidorova ZY,
Murina V, Atkinson GC, Konevega AL, Ignatova Z, Wilson
DN, Hauryliuk V |
(2021) "RqcH and
RqcP catalyze processive poly-alanine synthesis in a
reconstituted ribosome-associated quality control
system." Nucleic Acids Res.,
49, 8355-8369. doi: 10.1093/nar/gkab589.
|
Rqch dr variant bound to 50s-peptidyl-trna-rqcp rqc
complex (rigid body refinement) . SNAP output
|
|
7oqb
|
splicing |
cryo-EM (9.0 Å) |
Zhang Z, Rigo N, Dybkov O, Fourmann JB, Will CL,
Kumar V, Urlaub H, Stark H, Luhrmann R |
(2021) "Structural
insights into how Prp5 proofreads the pre-mRNA branch
site." Nature, 596,
296-300. doi: 10.1038/s41586-021-03789-5.
|
The u2 part of saccharomyces cerevisiae spliceosomal
pre-a complex (delta bs-a act1) . SNAP output
|
|
7oqc
|
splicing |
cryo-EM (4.1 Å) |
Zhang Z, Rigo N, Dybkov O, Fourmann JB, Will CL,
Kumar V, Urlaub H, Stark H, Luhrmann R |
(2021) "Structural
insights into how Prp5 proofreads the pre-mRNA branch
site." Nature, 596,
296-300. doi: 10.1038/s41586-021-03789-5.
|
The u1 part of saccharomyces cerevisiae spliceosomal
pre-a complex (delta bs-a act1) . SNAP output
|
|
7oqe
|
splicing |
cryo-EM (5.9 Å) |
Zhang Z, Rigo N, Dybkov O, Fourmann JB, Will CL,
Kumar V, Urlaub H, Stark H, Luhrmann R |
(2021) "Structural
insights into how Prp5 proofreads the pre-mRNA branch
site." Nature, 596,
296-300. doi: 10.1038/s41586-021-03789-5.
|
Saccharomyces cerevisiae spliceosomal pre-a complex
(delta bs-a act1) . SNAP
output
|
|
7ori
|
viral protein |
cryo-EM (3.9 Å) |
Arragain B, Durieux Trouilleton Q, Baudin F,
Provaznik J, Azevedo N, Cusack S, Schoehn G, Malet H |
(2022) "Structural
snapshots of La Crosse virus polymerase reveal the
mechanisms underlying Peribunyaviridae replication and
transcription." Nat Commun,
13, 902. doi: 10.1038/s41467-022-28428-z.
|
La crosse virus polymerase at replication
late-elongation stage . SNAP output
|
|
7orj
|
viral protein |
cryo-EM (3.9 Å) |
Arragain B, Durieux Trouilleton Q, Baudin F,
Provaznik J, Azevedo N, Cusack S, Schoehn G, Malet H |
(2022) "Structural
snapshots of La Crosse virus polymerase reveal the
mechanisms underlying Peribunyaviridae replication and
transcription." Nat Commun,
13, 902. doi: 10.1038/s41467-022-28428-z.
|
La crosse virus polymerase at transcription capped RNA
cleavage stage . SNAP
output
|
|
7ork
|
viral protein |
cryo-EM (3.1 Å) |
Arragain B, Durieux Trouilleton Q, Baudin F,
Provaznik J, Azevedo N, Cusack S, Schoehn G, Malet H |
(2022) "Structural
snapshots of La Crosse virus polymerase reveal the
mechanisms underlying Peribunyaviridae replication and
transcription." Nat Commun,
13, 902. doi: 10.1038/s41467-022-28428-z.
|
La crosse virus polymerase in transcription mode with
cleaved capped RNA entering the polymerase active site
. SNAP output
|
|
7orl
|
viral protein |
cryo-EM (3.6 Å) |
Arragain B, Durieux Trouilleton Q, Baudin F,
Provaznik J, Azevedo N, Cusack S, Schoehn G, Malet H |
(2022) "Structural
snapshots of La Crosse virus polymerase reveal the
mechanisms underlying Peribunyaviridae replication and
transcription." Nat Commun,
13, 902. doi: 10.1038/s41467-022-28428-z.
|
La crosse virus polymerase at transcription initiation
stage . SNAP output
|
|
7orm
|
viral protein |
cryo-EM (3.3 Å) |
Arragain B, Durieux Trouilleton Q, Baudin F,
Provaznik J, Azevedo N, Cusack S, Schoehn G, Malet H |
(2022) "Structural
snapshots of La Crosse virus polymerase reveal the
mechanisms underlying Peribunyaviridae replication and
transcription." Nat Commun,
13, 902. doi: 10.1038/s41467-022-28428-z.
|
La crosse virus polymerase at transcription
early-elongation stage . SNAP output
|
|
7orn
|
viral protein |
cryo-EM (2.8 Å) |
Arragain B, Durieux Trouilleton Q, Baudin F,
Provaznik J, Azevedo N, Cusack S, Schoehn G, Malet H |
(2022) "Structural
snapshots of La Crosse virus polymerase reveal the
mechanisms underlying Peribunyaviridae replication and
transcription." Nat Commun,
13, 902. doi: 10.1038/s41467-022-28428-z.
|
La crosse virus polymerase at replication initiation
stage . SNAP output
|
|
7oro
|
viral protein |
cryo-EM (2.9 Å) |
Arragain B, Durieux Trouilleton Q, Baudin F,
Provaznik J, Azevedo N, Cusack S, Schoehn G, Malet H |
(2022) "Structural
snapshots of La Crosse virus polymerase reveal the
mechanisms underlying Peribunyaviridae replication and
transcription." Nat Commun,
13, 902. doi: 10.1038/s41467-022-28428-z.
|
La crosse virus polymerase at replication
early-elongation stage . SNAP output
|
|
7os0
|
RNA binding protein |
X-ray (2.2 Å) |
Kick LM, von Wrisberg MK, Runtsch LS, Schneider
S |
(2022) "Structure
and mechanism of the RNA dependent RNase Cas13a from
Rhodobacter capsulatus." Commun Biol,
5, 71. doi: 10.1038/s42003-022-03025-4.
|
Structure of the rhodobacter capsulatus cas13a-crrna
binary complex . SNAP
output
|
|
7osa
|
ribosome |
X-ray (3.0 Å) |
Djumagulov M, Demeshkina N, Jenner L, Rozov A,
Yusupov M, Yusupova G |
(2021) "Accuracy
mechanism of eukaryotic ribosome translocation."
Nature, 600, 543-546. doi:
10.1038/s41586-021-04131-9.
|
Pre-translocation complex of 80 s.cerevisiae ribosome
with eef2 and ligands . SNAP output
|
|
7osm
|
ribosome |
X-ray (3.0 Å) |
Djumagulov M, Demeshkina N, Jenner L, Rozov A,
Yusupov M, Yusupova G |
(2021) "Accuracy
mechanism of eukaryotic ribosome translocation."
Nature, 600, 543-546. doi:
10.1038/s41586-021-04131-9.
|
Intermediate translocation complex of 80 s.cerevisiae
ribosome with eef2 and ligands . SNAP output
|
|
7ot5
|
ribosome |
cryo-EM (2.9 Å) |
Agirrezabala X, Samatova E, Macher M, Liutkute M,
Maiti M, Gil-Carton D, Novacek J, Valle M, Rodnina
MV |
(2022) "A switch
from alpha-helical to beta-strand conformation during
co-translational protein folding." Embo
J., 41, e109175. doi: 10.15252/embj.2021109175.
|
Cspa-70 cotranslational folding intermediate 1 .
SNAP output
|
|
7otc
|
ribosome |
cryo-EM (2.9 Å) |
Wieland M, Holm M, Rundlet EJ, Morici M, Koller TO,
Maviza TP, Pogorevc D, Osterman IA, Muller R, Blanchard
SC, Wilson DN |
(2022) "The
cyclic octapeptide antibiotic argyrin B inhibits
translation by trapping EF-G on the ribosome during
translocation." Proc.Natl.Acad.Sci.USA,
119, e2114214119. doi: 10.1073/pnas.2114214119.
|
cryo-EM structure of an escherichia coli 70s ribosome
in complex with elongation factor g and the antibiotic
argyrin b . SNAP
output
|
|
7ow7
|
translation |
cryo-EM (2.4 Å) |
Faille A, Warren AJ |
"Structure of human EIF6-bound large ribosomal
subunit." |
Eif6-bound large subunit of the human ribosome .
SNAP output
|
|
7oya
|
ribosome |
cryo-EM (3.2 Å) |
Leesch F, Lorenzo-Orts L, Pribitzer C, Grishkovskaya
I, Roehsner J, Chugunova A, Matzinger M, Roitinger E,
Belacic K, Kandolf S, Lin TY, Mechtler K, Meinhart A,
Haselbach D, Pauli A |
(2023) "A
molecular network of conserved factors keeps ribosomes
dormant in the egg." Nature,
613, 712-720. doi: 10.1038/s41586-022-05623-y.
|
cryo-EM structure of the 1 hpf zebrafish embryo 80s
ribosome . SNAP
output
|
|
7oyb
|
ribosome |
cryo-EM (2.4 Å) |
Leesch F, Lorenzo-Orts L, Pribitzer C, Grishkovskaya
I, Roehsner J, Chugunova A, Matzinger M, Roitinger E,
Belacic K, Kandolf S, Lin TY, Mechtler K, Meinhart A,
Haselbach D, Pauli A |
(2023) "A
molecular network of conserved factors keeps ribosomes
dormant in the egg." Nature,
613, 712-720. doi: 10.1038/s41586-022-05623-y.
|
cryo-EM structure of the 6 hpf zebrafish embryo 80s
ribosome . SNAP
output
|
|
7oyc
|
ribosome |
cryo-EM (2.4 Å) |
Leesch F, Lorenzo-Orts L, Pribitzer C, Grishkovskaya
I, Roehsner J, Chugunova A, Matzinger M, Roitinger E,
Belacic K, Kandolf S, Lin TY, Mechtler K, Meinhart A,
Haselbach D, Pauli A |
(2023) "A
molecular network of conserved factors keeps ribosomes
dormant in the egg." Nature,
613, 712-720. doi: 10.1038/s41586-022-05623-y.
|
cryo-EM structure of the xenopus egg 80s ribosome .
SNAP output
|
|
7oyd
|
ribosome |
cryo-EM (2.3 Å) |
Leesch F, Lorenzo-Orts L, Pribitzer C, Grishkovskaya
I, Roehsner J, Chugunova A, Matzinger M, Roitinger E,
Belacic K, Kandolf S, Lin TY, Mechtler K, Meinhart A,
Haselbach D, Pauli A |
(2023) "A
molecular network of conserved factors keeps ribosomes
dormant in the egg." Nature,
613, 712-720. doi: 10.1038/s41586-022-05623-y.
|
cryo-EM structure of a rabbit 80s ribosome with
zebrafish dap1b . SNAP
output
|
|
7oyg
|
viral protein |
cryo-EM (5.5 Å) |
Jochheim FA, Tegunov D, Hillen HS, Schmitzova J,
Kokic G, Dienemann C, Cramer P |
(2021) "The structure of a dimeric form of SARS-CoV-2
polymerase." Communications Biology,
4, 999. doi: 10.1038/s42003-021-02529-9.
|
Dimeric form of sars-cov-2 RNA-dependent RNA polymerase
. SNAP output
|
|
7ozq
|
ribosomal protein |
X-ray (1.91 Å) |
Hofler S, Lukat P, Blankenfeldt W, Carlomagno T |
(2021) "Eukaryotic
Box C/D methylation machinery has two non-symmetric
protein assembly sites." Sci Rep,
11, 17561. doi: 10.1038/s41598-021-97030-y.
|
Crystal structure of archaeal l7ae bound to eukaryotic
kink-loop . SNAP
output
|
|
7ozr
|
virus |
cryo-EM (4.5 Å) |
Zhang X, Sridharan S, Zagoriy I, Eugster Oegema C,
Ching C, Pflaesterer T, Fung HKH, Becher I, Poser I,
Muller CW, Hyman AA, Savitski MM, Mahamid J |
(2023) "Molecular
mechanisms of stress-induced reactivation in mumps
virus condensates." Cell,
186, 1877-1894.e27. doi: 10.1016/j.cell.2023.03.015.
|
Subtomogram average of authentic mumps virus
nucleocapsid from hela cell lysate of long helical
pitch . SNAP output
|
|
7ozs
|
RNA binding protein |
cryo-EM (3.5 Å) |
Castillo Duque de Estrada NM, Thoms M, Flemming D,
Hammaren HM, Buschauer R, Ameismeier M, Bassler J, Beck
M, Beckmann R, Hurt E |
(2023) "Structure
of nascent 5S RNPs at the crossroad between ribosome
assembly and MDM2-p53 pathways."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-023-01006-7.
|
Structure of the hexameric 5s rnp from c. thermophilum
. SNAP output
|
|
7ozu
|
viral protein |
cryo-EM (3.3 Å) |
Kabinger F, Stiller C, Schmitzova J, Dienemann C,
Kokic G, Hillen HS, Hobartner C, Cramer P |
(2021) "Mechanism
of molnupiravir-induced SARS-CoV-2 mutagenesis."
Nat.Struct.Mol.Biol., 28,
740-746. doi: 10.1038/s41594-021-00651-0.
|
Sars-cov-2 rdrp with molnupiravir- nhc in the template
strand base-paired with a . SNAP output
|
|
7ozv
|
viral protein |
cryo-EM (3.2 Å) |
Kabinger F, Stiller C, Schmitzova J, Dienemann C,
Kokic G, Hillen HS, Hobartner C, Cramer P |
(2021) "Mechanism
of molnupiravir-induced SARS-CoV-2 mutagenesis."
Nat.Struct.Mol.Biol., 28,
740-746. doi: 10.1038/s41594-021-00651-0.
|
Sars-cov-2 rdrp with molnupiravir- nhc in the template
strand base-paired with g . SNAP output
|
|
7p0v
|
RNA binding protein |
X-ray (1.56 Å) |
de Vries T, Martelly W, Campagne S, Sabath K,
Sarnowski CP, Wong J, Leitner A, Jonas S, Sharma S,
Allain FH |
(2022) "Sequence-specific
RNA recognition by an RGG motif connects U1 and U2
snRNP for spliceosome assembly."
Proc.Natl.Acad.Sci.USA, 119.
doi: 10.1073/pnas.2114092119.
|
Crystal structure of human sf3a1 ubiquitin-like domain
in complex with u1 snrna stem-loop 4 . SNAP output
|
|
7p2e
|
ribosome |
cryo-EM (2.4 Å) |
Itoh Y, Singh V, Khawaja A, Naschberger A, Nguyen MD,
Rorbach J, Amunts A |
(2022) "Structure
of the mitoribosomal small subunit with streptomycin
reveals Fe-S clusters and physiological molecules."
Elife, 11. doi: 10.7554/eLife.77460.
|
Human mitochondrial ribosome small subunit in complex
with if3, gmppmp and streptomycin . SNAP output
|
|
7p3k
|
ribosome |
cryo-EM (2.9 Å) |
Su T, Kudva R, Becker T, Buschauer R, Komar T,
Berninghausen O, von Heijne G, Cheng J, Beckmann R |
(2021) "Structural
basis of l-tryptophan-dependent inhibition of release
factor 2 by the TnaC arrest peptide." Nucleic
Acids Res., 49, 9539-9547. doi:
10.1093/nar/gkab665.
|
cryo-EM structure of 70s ribosome stalled with tnac
peptide (control) . SNAP
output
|
|
7p48
|
ribosomal protein |
cryo-EM (2.9 Å) |
Mohamad M, Nicholson D, Saha CK, Hauryliuk V, Edwards
TA, Atkinson GC, Ranson NA, O'Neill AJ |
(2022) "Sal-type
ABC-F proteins: intrinsic and common mediators of
pleuromutilin resistance by target protection in
staphylococci." Nucleic Acids Res.,
50, 2128-2142. doi: 10.1093/nar/gkac058.
|
Staphylococcus aureus ribosome in complex with sal(b) .
SNAP output
|
|
7p6z
|
ribosome |
cryo-EM (3.5 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
Mycoplasma pneumoniae 70s ribosome in untreated cells .
SNAP output
|
|
7p7q
|
ribosome |
cryo-EM (2.4 Å) |
Crowe-McAuliffe C, Murina V, Turnbull KJ, Huch S,
Kasari M, Takada H, Nersisyan L, Sundsfjord A, Hegstad K,
Atkinson GC, Pelechano V, Wilson DN, Hauryliuk V |
(2022) "Structural
basis for PoxtA-mediated resistance to phenicol and
oxazolidinone antibiotics." Nat Commun,
13, 1860. doi: 10.1038/s41467-022-29274-9.
|
E. faecalis 70s ribosome bound by poxta-eq2,
high-resolution combined volume . SNAP output
|
|
7p7r
|
ribosome |
cryo-EM (2.9 Å) |
Crowe-McAuliffe C, Murina V, Turnbull KJ, Huch S,
Kasari M, Takada H, Nersisyan L, Sundsfjord A, Hegstad K,
Atkinson GC, Pelechano V, Wilson DN, Hauryliuk V |
(2022) "Structural
basis for PoxtA-mediated resistance to phenicol and
oxazolidinone antibiotics." Nat Commun,
13, 1860. doi: 10.1038/s41467-022-29274-9.
|
Poxta-eq2 antibiotic resistance abcf bound to e.
faecalis 70s ribosome, state i . SNAP output
|
|
7p7s
|
ribosome |
cryo-EM (3.0 Å) |
Crowe-McAuliffe C, Murina V, Turnbull KJ, Huch S,
Kasari M, Takada H, Nersisyan L, Sundsfjord A, Hegstad K,
Atkinson GC, Pelechano V, Wilson DN, Hauryliuk V |
(2022) "Structural
basis for PoxtA-mediated resistance to phenicol and
oxazolidinone antibiotics." Nat Commun,
13, 1860. doi: 10.1038/s41467-022-29274-9.
|
Poxta-eq2 antibiotic resistance abcf bound to e.
faecalis 70s ribosome, state ii . SNAP output
|
|
7p7t
|
ribosome |
cryo-EM (2.9 Å) |
Crowe-McAuliffe C, Murina V, Turnbull KJ, Huch S,
Kasari M, Takada H, Nersisyan L, Sundsfjord A, Hegstad K,
Atkinson GC, Pelechano V, Wilson DN, Hauryliuk V |
(2022) "Structural
basis for PoxtA-mediated resistance to phenicol and
oxazolidinone antibiotics." Nat Commun,
13, 1860. doi: 10.1038/s41467-022-29274-9.
|
Poxta-eq2 antibiotic resistance abcf bound to e.
faecalis 70s ribosome, state iii . SNAP output
|
|
7p7u
|
ribosome |
cryo-EM (3.1 Å) |
Crowe-McAuliffe C, Murina V, Turnbull KJ, Huch S,
Kasari M, Takada H, Nersisyan L, Sundsfjord A, Hegstad K,
Atkinson GC, Pelechano V, Wilson DN, Hauryliuk V |
(2022) "Structural
basis for PoxtA-mediated resistance to phenicol and
oxazolidinone antibiotics." Nat Commun,
13, 1860. doi: 10.1038/s41467-022-29274-9.
|
E. faecalis 70s ribosome with p-trna, state iv .
SNAP output
|
|
7p8q
|
RNA binding protein |
X-ray (2.289 Å) |
Meynier V, Iannazzo L, Catala M, Oerum S, Braud E,
Atdjian C, Barraud P, Fonvielle M, Tisne C,
Etheve-Quelquejeu M |
(2022) "Synthesis
of RNA-cofactor conjugates and structural exploration
of RNA recognition by an m6A RNA
methyltransferase." Nucleic Acids Res.,
50, 5793-5806. doi: 10.1093/nar/gkac354.
|
Structure of e.coli rlmj in complex with an RNA
conjugate (ga-sam) . SNAP output
|
|
7p9i
|
RNA binding protein |
X-ray (1.594 Å) |
Meynier V, Iannazzo L, Catala M, Oerum S, Braud E,
Atdjian C, Barraud P, Fonvielle M, Tisne C,
Etheve-Quelquejeu M |
(2022) "Synthesis
of RNA-cofactor conjugates and structural exploration
of RNA recognition by an m6A RNA
methyltransferase." Nucleic Acids Res.,
50, 5793-5806. doi: 10.1093/nar/gkac354.
|
Structure of e.coli rlmj in complex with an RNA
conjugate (gaa-sam) . SNAP output
|
|
7pah
|
translation |
cryo-EM (9.5 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with p- and e-site trnas in mycoplasma
pneumoniae cells . SNAP
output
|
|
7pai
|
translation |
cryo-EM (6.7 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with p-site trna in mycoplasma pneumoniae
cells . SNAP output
|
|
7paj
|
translation |
cryo-EM (7.3 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-tu-trna, p- and e-site trnas in
mycoplasma pneumoniae cells . SNAP output
|
|
7pak
|
translation |
cryo-EM (5.3 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-tu-trna and p-site trna in
mycoplasma pneumoniae cells . SNAP output
|
|
7pal
|
translation |
cryo-EM (4.7 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with a- and p-site trnas in mycoplasma
pneumoniae cells . SNAP
output
|
|
7pam
|
translation |
cryo-EM (6.8 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with a*- and p-e-site trnas in mycoplasma
pneumoniae cells . SNAP
output
|
|
7pan
|
translation |
cryo-EM (9.7 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with a-p- and p-e-site trnas in mycoplasma
pneumoniae cells . SNAP
output
|
|
7pao
|
translation |
cryo-EM (7.0 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-g, a*- and p-e-site trnas in
mycoplasma pneumoniae cells . SNAP output
|
|
7paq
|
translation |
cryo-EM (8.9 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-g, a-p- and p-e-site trnas in
mycoplasma pneumoniae cells . SNAP output
|
|
7par
|
translation |
cryo-EM (8.2 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-g, ap-p- and pe-e-site trnas in
mycoplasma pneumoniae cells . SNAP output
|
|
7pas
|
translation |
cryo-EM (16.0 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with p-e-site trna in mycoplasma
pneumoniae cells . SNAP
output
|
|
7pat
|
ribosome |
cryo-EM (9.2 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
Free 50s in untreated mycoplasma pneumoniae cells .
SNAP output
|
|
7pau
|
ribosome |
cryo-EM (8.3 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
Free 50s in complex with ribosome recycling factor in
untreated mycoplasma pneumoniae cells . SNAP output
|
|
7pd3
|
ribosome |
cryo-EM (3.4 Å) |
Chandrasekaran V, Desai N, Burton NO, Yang H, Price
J, Miska EA, Ramakrishnan V |
(2021) "Visualizing
formation of the active site in the mitochondrial
ribosome." Elife, 10.
doi: 10.7554/eLife.68806.
|
Structure of the human mitoribosomal large subunit in
complex with nsun4.mterf4.gtpbp7 and
malsu1.l0r8f8.mt-acp . SNAP output
|
|
7pdv
|
RNA binding protein |
X-ray (3.49 Å) |
Soni K, Jagtap PKA, Martinez-Lumbreras S, Bonnal S,
Geerlof A, Stehle R, Simon B, Valcarcel J, Sattler M |
(2023) "Structural
basis for specific RNA recognition by the alternative
splicing factor RBM5." Nat Commun,
14, 4233. doi: 10.1038/s41467-023-39961-w.
|
Crystal structure of rbm5 rrm1-zinc finger in complex
with RNA . SNAP
output
|
|
7ph9
|
translation |
cryo-EM (8.7 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with p-site trna in
chloramphenicol-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pha
|
translation |
cryo-EM (8.5 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-tu-trna and p-site trna in
chloramphenicol-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7phb
|
translation |
cryo-EM (4.9 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with a- and p-site trnas in
chloramphenicol-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7phc
|
translation |
cryo-EM (9.9 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with a*- and p-e-site trnas in
chloramphenicol-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pi8
|
translation |
cryo-EM (8.9 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with p-site trna in spectinomycin-treated
mycoplasma pneumoniae cells . SNAP output
|
|
7pi9
|
translation |
cryo-EM (6.3 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-tu-trna and p-site trna in
spectinomycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pia
|
translation |
cryo-EM (13.6 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with a-p- and p-e-site trnas in
spectinomycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pib
|
translation |
cryo-EM (4.7 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-g, a-p- and p-e-site trnas in
spectinomycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pic
|
translation |
cryo-EM (9.1 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with p-e-site trna in
spectinomycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pio
|
translation |
cryo-EM (9.5 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with p-site trna in
pseudouridimycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pip
|
translation |
cryo-EM (9.3 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-tu-trna and p-site trna in
pseudouridimycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7piq
|
translation |
cryo-EM (9.7 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with a- and p-site trnas in
pseudouridimycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pir
|
translation |
cryo-EM (12.1 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with a*- and p-e-site trnas in
pseudouridimycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pis
|
translation |
cryo-EM (15.0 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-g, a*- and p-e-site trnas in
pseudouridimycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pit
|
translation |
cryo-EM (5.7 Å) |
Xue L, Lenz S, Zimmermann-Kogadeeva M, Tegunov D,
Cramer P, Bork P, Rappsilber J, Mahamid J |
(2022) "Visualizing
translation dynamics at atomic detail inside a
bacterial cell." Nature,
610, 205-211. doi: 10.1038/s41586-022-05255-2.
|
70s ribosome with ef-g, a-p- and p-e-site trnas in
pseudouridimycin-treated mycoplasma pneumoniae cells .
SNAP output
|
|
7pjs
|
ribosome |
cryo-EM (2.35 Å) |
Petrychenko V, Peng BZ, Schwarzer AC, Peske F,
Rodnina MV, Fischer N |
(2021) "Structural mechanism of GTPase-powered
ribosome-tRNA movement." Nat Commun,
12, 5933. doi: 10.1038/s41467-021-26133-x.
|
Structure of the 70s ribosome with trnas in the
classical pre-translocation state and apramycin (c) .
SNAP output
|
|
7pjt
|
ribosome |
cryo-EM (6.0 Å) |
Petrychenko V, Peng BZ, de A P Schwarzer AC, Peske F,
Rodnina MV, Fischer N |
(2021) "Structural
mechanism of GTPase-powered ribosome-tRNA
movement." Nat Commun,
12, 5933. doi: 10.1038/s41467-021-26133-x.
|
Structure of the 70s ribosome with trnas in hybrid
state 1 (h1) . SNAP
output
|
|
7pju
|
ribosome |
cryo-EM (9.5 Å) |
Petrychenko V, Peng BZ, de A P Schwarzer AC, Peske F,
Rodnina MV, Fischer N |
(2021) "Structural
mechanism of GTPase-powered ribosome-tRNA
movement." Nat Commun,
12, 5933. doi: 10.1038/s41467-021-26133-x.
|
Structure of the 70s ribosome with trnas in hybrid
state 2 (h2) . SNAP
output
|
|
7pjv
|
ribosome |
cryo-EM (3.1 Å) |
Petrychenko V, Peng BZ, de A P Schwarzer AC, Peske F,
Rodnina MV, Fischer N |
(2021) "Structural
mechanism of GTPase-powered ribosome-tRNA
movement." Nat Commun,
12, 5933. doi: 10.1038/s41467-021-26133-x.
|
Structure of the 70s-ef-g-gdp-pi ribosome complex with
trnas in hybrid state 1 (h1-ef-g-gdp-pi) . SNAP output
|
|
7pjw
|
ribosome |
cryo-EM (4.0 Å) |
Petrychenko V, Peng BZ, de A P Schwarzer AC, Peske F,
Rodnina MV, Fischer N |
(2021) "Structural
mechanism of GTPase-powered ribosome-tRNA
movement." Nat Commun,
12, 5933. doi: 10.1038/s41467-021-26133-x.
|
Structure of the 70s-ef-g-gdp-pi ribosome complex with
trnas in hybrid state 2 (h2-ef-g-gdp-pi) . SNAP output
|
|
7pjx
|
ribosome |
cryo-EM (6.5 Å) |
Petrychenko V, Peng BZ, de A P Schwarzer AC, Peske F,
Rodnina MV, Fischer N |
(2021) "Structural
mechanism of GTPase-powered ribosome-tRNA
movement." Nat Commun,
12, 5933. doi: 10.1038/s41467-021-26133-x.
|
Structure of the 70s-ef-g-gdp ribosome complex with
trnas in hybrid state 1 (h1-ef-g-gdp) . SNAP output
|
|
7pjy
|
ribosome |
cryo-EM (3.1 Å) |
Petrychenko V, Peng BZ, de A P Schwarzer AC, Peske F,
Rodnina MV, Fischer N |
(2021) "Structural
mechanism of GTPase-powered ribosome-tRNA
movement." Nat Commun,
12, 5933. doi: 10.1038/s41467-021-26133-x.
|
Structure of the 70s-ef-g-gdp ribosome complex with
trnas in chimeric state 1 (chi1-ef-g-gdp) . SNAP output
|
|
7pjz
|
ribosome |
cryo-EM (6.0 Å) |
Petrychenko V, Peng BZ, de A P Schwarzer AC, Peske F,
Rodnina MV, Fischer N |
(2021) "Structural
mechanism of GTPase-powered ribosome-tRNA
movement." Nat Commun,
12, 5933. doi: 10.1038/s41467-021-26133-x.
|
Structure of the 70s-ef-g-gdp ribosome complex with
trnas in chimeric state 2 (chi2-ef-g-gdp) . SNAP output
|
|
7pkq
|
ribosome |
cryo-EM (4.2 Å) |
Waltz F, Salinas-Giege T, Englmeier R, Meichel H,
Soufari H, Kuhn L, Pfeffer S, Foerster F, Engel BD, Giege
P, Drouard L, Hashem Y |
"The Chlamydomonas mitochondrial ribosome: how to
build a ribosome from RNA fragments." |
Small subunit of the chlamydomonas reinhardtii
mitoribosome . SNAP
output
|
|
7pkt
|
ribosome |
cryo-EM (3.0 Å) |
Waltz F, Salinas-Giege T, Englmeier R, Meichel H,
Soufari H, Kuhn L, Pfeffer S, Forster F, Engel BD, Giege
P, Drouard L, Hashem Y |
(2021) "How to
build a ribosome from RNA fragments in Chlamydomonas
mitochondria." Nat Commun,
12, 7176. doi: 10.1038/s41467-021-27200-z.
|
Large subunit of the chlamydomonas reinhardtii
mitoribosome . SNAP
output
|
|
7pmm
|
RNA binding protein |
X-ray (3.0 Å) |
Wurm JP |
(2023) "Structural
basis for RNA-duplex unwinding by the DEAD-box helicase
DbpA." Rna, 29,
1339-1354. doi: 10.1261/rna.079582.123.
|
Dead-box helicase dbpa in the active conformation bound
to a ss-dsrna junction and adp-bef3 . SNAP output
|
|
7pmq
|
RNA binding protein |
X-ray (3.22 Å) |
Wurm JP |
(2023) "Structural
basis for RNA-duplex unwinding by the DEAD-box helicase
DbpA." Rna, 29,
1339-1354. doi: 10.1261/rna.079582.123.
|
Dead-box helicase dbpa in the active conformation bound
to a hairpin loop RNA and adp-bef3 . SNAP output
|
|
7pnt
|
ribosome |
cryo-EM (3.19 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Assembly intermediate of mouse mitochondrial ribosome
small subunit without ms37 in complex with rbfa and
tfb1m . SNAP output
|
|
7pnu
|
ribosome |
cryo-EM (3.06 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Assembly intermediate of mouse mitochondrial ribosome
small subunit without ms37 in complex with rbfa inward
conformation . SNAP
output
|
|
7pnv
|
ribosome |
cryo-EM (3.06 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Assembly intermediate of mouse mitochondrial ribosome
small subunit without ms37 in complex with rbfa and
mettl15 . SNAP
output
|
|
7pnw
|
ribosome |
cryo-EM (3.09 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Mouse mitochondrial ribosome small subunit lacking m5u
modification . SNAP
output
|
|
7pnx
|
ribosome |
cryo-EM (2.76 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Assembly intermediate of human mitochondrial ribosome
small subunit without ms37 in complex with rbfa and
mettl15 conformation a . SNAP output
|
|
7pny
|
ribosome |
cryo-EM (3.06 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Assembly intermediate of human mitochondrial ribosome
small subunit without ms37 in complex with rbfa and
mettl15 conformation b . SNAP output
|
|
7pnz
|
ribosome |
cryo-EM (3.09 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Assembly intermediate of human mitochondrial ribosome
small subunit without ms37 in complex with rbfa and
mettl15 conformation c . SNAP output
|
|
7po0
|
ribosome |
cryo-EM (2.9 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Assembly intermediate of human mitochondrial ribosome
small subunit without ms37 in complex with rbfa and if3
. SNAP output
|
|
7po1
|
ribosome |
cryo-EM (2.92 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Initiation complex of human mitochondrial ribosome
small subunit with if3 . SNAP output
|
|
7po2
|
ribosome |
cryo-EM (3.09 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Initiation complex of human mitochondrial ribosome
small subunit with if2, fmet-trnamet and mrna .
SNAP output
|
|
7po3
|
ribosome |
cryo-EM (2.92 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Human mitochondrial ribosome small subunit . SNAP output
|
|
7po4
|
ribosome |
cryo-EM (2.56 Å) |
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I,
Sergiev P, Rorbach J, Amunts A |
(2022) "Mechanism
of mitoribosomal small subunit biogenesis and
preinitiation." Nature,
606, 603-608. doi: 10.1038/s41586-022-04795-x.
|
Assembly intermediate of human mitochondrial ribosome
large subunit (largely unfolded rrna with malsu1,
l0r8f8 and acp) . SNAP
output
|
|
7po6
|
RNA binding protein |
X-ray (1.77 Å) |
Jones AN, Tikhaia E, Mourao A, Sattler M |
(2022) "Structural
effects of m6A modification of the Xist A-repeat AUCG
tetraloop and its recognition by YTHDC1."
Nucleic Acids Res., 50,
2350-2362. doi: 10.1093/nar/gkac080.
|
Xist (m6a)ucg tetraloop RNA bound to the yth domain of
ythdc1 . SNAP output
|
|
7pua
|
ribosome |
cryo-EM (3.6 Å) |
Lenarcic T, Niemann M, Ramrath DJF, Calderaro S,
Flugel T, Saurer M, Leibundgut M, Boehringer D, Prange C,
Horn EK, Schneider A, Ban N |
(2022) "Mitoribosomal
small subunit maturation involves formation of
initiation-like complexes."
Proc.Natl.Acad.Sci.USA, 119.
doi: 10.1073/pnas.2114710118.
|
Middle assembly intermediate of the trypanosoma brucei
mitoribosomal small subunit . SNAP output
|
|
7pub
|
ribosome |
cryo-EM (3.7 Å) |
Lenarcic T, Niemann M, Ramrath DJF, Calderaro S,
Flugel T, Saurer M, Leibundgut M, Boehringer D, Prange C,
Horn EK, Schneider A, Ban N |
(2022) "Mitoribosomal
small subunit maturation involves formation of
initiation-like complexes."
Proc.Natl.Acad.Sci.USA, 119.
doi: 10.1073/pnas.2114710118.
|
Late assembly intermediate of the trypanosoma brucei
mitoribosomal small subunit . SNAP output
|
|
7pvk
|
signaling protein |
X-ray (2.4 Å) |
Schmitz C, Madej M, Nowakowska Z, Cuppari A, Jacula
A, Ksiazek M, Mikruta K, Wisniewski J, Pudelko-Malik N,
Saran A, Zeytuni N, Mlynarz P, Lamont RJ, Uson I, Siksnys
V, Potempa J, Sola M |
(2022) "Response regulator PorX coordinates
oligonucleotide signalling and gene expression to
control the secretion of virulence factors."
Nucleic Acids Res., 50,
12558-12577. doi: 10.1093/nar/gkac1103.
|
X-ray structure of dimeric porx (t272a mutant), in
complex with pgpg. . SNAP output
|
|
7pwf
|
ribosome |
cryo-EM (2.85 Å) |
Hiregange DG, Rivalta A, Bose T, Breiner-Goldstein E,
Samiya S, Cimicata G, Kulakova L, Zimmerman E, Bashan A,
Herzberg O, Yonath A |
(2022) "Cryo-EM
structure of the ancient eukaryotic ribosome from the
human parasite Giardia lamblia." Nucleic Acids
Res., 50, 1770-1782. doi:
10.1093/nar/gkac046.
|
cryo-EM structure of small subunit of giardia lamblia
ribosome at 2.9 Å resolution . SNAP output
|
|
7pwg
|
ribosome |
cryo-EM (2.75 Å) |
Hiregange DG, Rivalta A, Bose T, Breiner-Goldstein E,
Samiya S, Cimicata G, Kulakova L, Zimmerman E, Bashan A,
Herzberg O, Yonath A |
(2022) "Cryo-EM
structure of the ancient eukaryotic ribosome from the
human parasite Giardia lamblia." Nucleic Acids
Res., 50, 1770-1782. doi:
10.1093/nar/gkac046.
|
cryo-EM structure of large subunit of giardia lamblia
ribosome at 2.7 Å resolution . SNAP output
|
|
7pwo
|
ribosome |
cryo-EM (2.75 Å) |
Hiregange DG, Rivalta A, Bose T, Breiner-Goldstein E,
Samiya S, Cimicata G, Kulakova L, Zimmerman E, Bashan A,
Herzberg O, Yonath A |
(2022) "Cryo-EM
structure of the ancient eukaryotic ribosome from the
human parasite Giardia lamblia." Nucleic Acids
Res., 50, 1770-1782. doi:
10.1093/nar/gkac046.
|
cryo-EM structure of giardia lamblia ribosome at 2.75 Å
resolution . SNAP
output
|
|
7pzy
|
ribosome |
cryo-EM (2.32 Å) |
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D,
Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G,
Sachs MS, Guskov A, Yusupov M |
(2022) "E-site
drug specificity of the human pathogen Candida albicans
ribosome." Sci Adv, 8,
eabn1062. doi: 10.1126/sciadv.abn1062.
|
Structure of the vacant candida albicans 80s ribosome .
SNAP output
|
|
7q08
|
ribosome |
cryo-EM (2.56 Å) |
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D,
Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G,
Sachs MS, Guskov A, Yusupov M |
(2022) "E-site
drug specificity of the human pathogen Candida albicans
ribosome." Sci Adv, 8,
eabn1062. doi: 10.1126/sciadv.abn1062.
|
Structure of candida albicans 80s ribosome in complex
with cycloheximide . SNAP output
|
|
7q0f
|
ribosome |
cryo-EM (2.64 Å) |
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D,
Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G,
Sachs MS, Guskov A, Yusupov M |
(2022) "E-site
drug specificity of the human pathogen Candida albicans
ribosome." Sci Adv, 8,
eabn1062. doi: 10.1126/sciadv.abn1062.
|
Structure of candida albicans 80s ribosome in complex
with phyllanthoside . SNAP output
|
|
7q0p
|
ribosome |
cryo-EM (2.77 Å) |
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D,
Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G,
Sachs MS, Guskov A, Yusupov M |
(2022) "E-site
drug specificity of the human pathogen Candida albicans
ribosome." Sci Adv, 8,
eabn1062. doi: 10.1126/sciadv.abn1062.
|
Structure of the candida albicans 80s ribosome in
complex with anisomycin . SNAP output
|
|
7q0r
|
ribosome |
cryo-EM (2.67 Å) |
Zgadzay Y, Kolosova O, Stetsenko A, Wu C, Bruchlen D,
Usachev K, Validov S, Jenner L, Rogachev A, Yusupova G,
Sachs MS, Guskov A, Yusupov M |
(2022) "E-site
drug specificity of the human pathogen Candida albicans
ribosome." Sci Adv, 8,
eabn1062. doi: 10.1126/sciadv.abn1062.
|
Structure of the candida albicans 80s ribosome in
complex with blasticidin s . SNAP output
|
|
7q22
|
virus |
cryo-EM (6.3 Å) |
Lazic I, Wirix M, Leidl ML, de Haas F, Mann D,
Beckers M, Pechnikova EV, Muller-Caspary K, Egoavil R,
Bosch EGT, Sachse C |
(2022) "Single-particle
cryo-EM structures from iDPC-STEM at near-atomic
resolution." Nat.Methods,
19, 1126-1136. doi: 10.1038/s41592-022-01586-0.
|
Cryo idpc-stem structure recorded with csa 2.0 .
SNAP output
|
|
7q23
|
virus |
cryo-EM (4.3 Å) |
Lazic I, Wirix M, Leidl ML, de Haas F, Mann D,
Beckers M, Pechnikova EV, Muller-Caspary K, Egoavil R,
Bosch EGT, Sachse C |
(2022) "Single-particle
cryo-EM structures from iDPC-STEM at near-atomic
resolution." Nat.Methods,
19, 1126-1136. doi: 10.1038/s41592-022-01586-0.
|
Cryo idpc-stem structure recorded with csa 3.0 .
SNAP output
|
|
7q2q
|
virus |
cryo-EM (4.3 Å) |
Lazic I, Wirix M, Leidl ML, de Haas F, Mann D,
Beckers M, Pechnikova EV, Muller-Caspary K, Egoavil R,
Bosch EGT, Sachse C |
(2022) "Single-particle
cryo-EM structures from iDPC-STEM at near-atomic
resolution." Nat.Methods,
19, 1126-1136. doi: 10.1038/s41592-022-01586-0.
|
Cryo idpc-stem structure recorded with csa 3.5 .
SNAP output
|
|
7q2r
|
virus |
cryo-EM (3.5 Å) |
Lazic I, Wirix M, Leidl ML, de Haas F, Mann D,
Beckers M, Pechnikova EV, Muller-Caspary K, Egoavil R,
Bosch EGT, Sachse C |
(2022) "Single-particle
cryo-EM structures from iDPC-STEM at near-atomic
resolution." Nat.Methods,
19, 1126-1136. doi: 10.1038/s41592-022-01586-0.
|
Cryo idpc-stem structure recorded with csa 4.0 .
SNAP output
|
|
7q2s
|
virus |
cryo-EM (3.7 Å) |
Lazic I, Wirix M, Leidl ML, de Haas F, Mann D,
Beckers M, Pechnikova EV, Muller-Caspary K, Egoavil R,
Bosch EGT, Sachse C |
(2022) "Single-particle
cryo-EM structures from iDPC-STEM at near-atomic
resolution." Nat.Methods,
19, 1126-1136. doi: 10.1038/s41592-022-01586-0.
|
Cryo idpc-stem structure recorded with csa 4.5 .
SNAP output
|
|
7q33
|
RNA binding protein |
NMR |
Campagne S, Jutzi D, Malard F, Matoga M, Romane K,
Feldmuller M, Colombo M, Ruepp MD, Allain FH |
(2023) "Molecular
basis of RNA-binding and autoregulation by the
cancer-associated splicing factor RBM39." Nat
Commun, 14, 5366. doi: 10.1038/s41467-023-40254-5.
|
Solution structure of rbm39 rrm2 bound to 5'-agcuuug-3
. SNAP output
|
|
7q3l
|
nuclear protein |
cryo-EM (2.21 Å) |
Tholen J, Razew M, Weis F, Galej WP |
(2022) "Structural
basis of branch site recognition by the human
spliceosome." Science,
375, 50-57. doi: 10.1126/science.abm4245.
|
Human 17s u2 snrnp 5' domain . SNAP output
|
|
7q4k
|
ribosome |
cryo-EM (3.0 Å) |
Fostier CR, Ousalem F, Leroy EC, Ngo S, Soufari H,
Innis CA, Hashem Y, Boel G |
(2023) "Regulation
of the macrolide resistance ABC-F translation factor
MsrD." Nat Commun, 14,
3891. doi: 10.1038/s41467-023-39553-8.
|
Erythromycin-stalled escherichia coli 70s ribosome with
streptococcal msrdl nascent chain . SNAP output
|
|
7q4l
|
RNA binding protein |
NMR |
Duszczyk MM, Wischnewski H, Kazeeva T, Arora R,
Loughlin FE, von Schroetter C, Pradere U, Hall J, Ciaudo
C, Allain FH |
(2022) "The
solution structure of Dead End bound to AU-rich RNA
reveals an unusual mode of tandem RRM-RNA recognition
required for mRNA regulation." Nat Commun,
13, 5892. doi: 10.1038/s41467-022-33552-x.
|
The solution structure of hsdnd1 rrm12 bound to
cuuauuug RNA . SNAP
output
|
|
7q4o
|
nuclear protein |
cryo-EM (2.1 Å) |
Tholen J, Razew M, Weis F, Galej WP |
(2022) "Structural
basis of branch site recognition by the human
spliceosome." Science,
375, 50-57. doi: 10.1126/science.abm4245.
|
Substrate-bound a-like u2 snrnp . SNAP output
|
|
7q4p
|
nuclear protein |
cryo-EM (2.15 Å) |
Tholen J, Razew M, Weis F, Galej WP |
(2022) "Structural
basis of branch site recognition by the human
spliceosome." Science,
375, 50-57. doi: 10.1126/science.abm4245.
|
U2 snrnp after atp-dependent remodelling . SNAP output
|
|
7qca
|
ribosome |
cryo-EM (2.79 Å) |
McLaren M, Conners R, Isupov MN, Gil-Diez P, Gambelli
L, Gold VAM, Walter A, Connell SR, Williams B, Daum
B |
(2023) "CryoEM reveals that ribosomes in microsporidian
spores are locked in a dimeric hibernating state."
Nat Microbiol. doi: 10.1038/s41564-023-01469-w.
|
Spraguea lophii ribosome . SNAP output
|
|
7qdd
|
RNA binding protein |
NMR |
Moursy A, Clery A, Gerhardy S, Betz KM, Rao S, Mazur
J, Campagne S, Beusch I, Duszczyk MM, Robinson MD, Panse
VG, Allain FH |
(2023) "RNA
recognition by Npl3p reveals U2 snRNA-binding
compatible with a chaperone role during splicing."
Nat Commun, 14, 7166. doi:
10.1038/s41467-023-42962-4.
|
NMR structure of npl3 rrm1 bound to the auccaa RNA .
SNAP output
|
|
7qde
|
RNA binding protein |
NMR |
Moursy A, Clery A, Gerhardy S, Betz KM, Rao S, Mazur
J, Campagne S, Beusch I, Duszczyk MM, Robinson MD, Panse
VG, Allain FH |
(2023) "RNA
recognition by Npl3p reveals U2 snRNA-binding
compatible with a chaperone role during splicing."
Nat Commun, 14, 7166. doi:
10.1038/s41467-023-42962-4.
|
NMR structure of npl3 rrm12 bound to the auccaguggaa
RNA . SNAP output
|
|
7qdy
|
RNA binding protein |
cryo-EM (3.1 Å) |
Kogel A, Keidel A, Bonneau F, Schafer IB, Conti
E |
(2022) "The
human SKI complex regulates channeling of
ribosome-bound RNA to the exosome via an intrinsic
gatekeeping mechanism." Mol.Cell,
82, 756. doi: 10.1016/j.molcel.2022.01.009.
|
RNA-bound human ski complex . SNAP output
|
|
7qdz
|
RNA binding protein |
cryo-EM (3.6 Å) |
Kogel A, Keidel A, Bonneau F, Schafer IB, Conti
E |
(2022) "The
human SKI complex regulates channeling of
ribosome-bound RNA to the exosome via an intrinsic
gatekeeping mechanism." Mol.Cell,
82, 756. doi: 10.1016/j.molcel.2022.01.009.
|
80s-bound human ski complex in the closed state .
SNAP output
|
|
7qe0
|
RNA binding protein |
cryo-EM (6.5 Å) |
Kogel A, Keidel A, Bonneau F, Schafer IB, Conti
E |
(2022) "The
human SKI complex regulates channeling of
ribosome-bound RNA to the exosome via an intrinsic
gatekeeping mechanism." Mol.Cell,
82, 756. doi: 10.1016/j.molcel.2022.01.009.
|
80s-bound human ski complex in the open state .
SNAP output
|
|
7qep
|
ribosome |
cryo-EM (2.7 Å) |
Nicholson D, Salamina M, Panek J, Helena-Bueno K,
Brown CR, Hirt RP, Ranson NA, Melnikov SV |
(2022) "Adaptation to genome decay in the structure of
the smallest eukaryotic ribosome." Nat Commun,
13, 591. doi: 10.1038/s41467-022-28281-0.
|
cryo-EM structure of the ribosome from encephalitozoon
cuniculi . SNAP
output
|
|
7qg8
|
ribosome |
cryo-EM (3.97 Å) |
Saito K, Kratzat H, Campbell A, Buschauer R,
Burroughs AM, Berninghausen O, Aravind L, Green R,
Beckmann R, Buskirk AR |
(2022) "Ribosome
collisions induce mRNA cleavage and ribosome rescue in
bacteria." Nature, 603,
503-508. doi: 10.1038/s41586-022-04416-7.
|
Structure of the collided e. coli disome - vemp-stalled
70s ribosome . SNAP
output
|
|
7qgh
|
ribosome |
cryo-EM (4.48 Å) |
Saito K, Kratzat H, Campbell A, Buschauer R,
Burroughs AM, Berninghausen O, Aravind L, Green R,
Beckmann R, Buskirk AR |
(2022) "Ribosome
collisions induce mRNA cleavage and ribosome rescue in
bacteria." Nature, 603,
503-508. doi: 10.1038/s41586-022-04416-7.
|
Structure of the e. coli disome - collided 70s ribosome
. SNAP output
|
|
7qgn
|
ribosome |
cryo-EM (3.37 Å) |
Saito K, Kratzat H, Campbell A, Buschauer R,
Burroughs AM, Berninghausen O, Aravind L, Green R,
Beckmann R, Buskirk AR |
(2022) "Ribosome
collisions induce mRNA cleavage and ribosome rescue in
bacteria." Nature, 603,
503-508. doi: 10.1038/s41586-022-04416-7.
|
Structure of the smrb-bound e. coli disome - stalled
70s ribosome . SNAP
output
|
|
7qgr
|
ribosome |
cryo-EM (5.7 Å) |
Saito K, Kratzat H, Campbell A, Buschauer R,
Burroughs AM, Berninghausen O, Aravind L, Green R,
Beckmann R, Buskirk AR |
(2022) "Ribosome
collisions induce mRNA cleavage and ribosome rescue in
bacteria." Nature, 603,
503-508. doi: 10.1038/s41586-022-04416-7.
|
Structure of the smrb-bound e. coli disome - collided
70s ribosome . SNAP
output
|
|
7qgu
|
ribosome |
cryo-EM (4.75 Å) |
Saito K, Kratzat H, Campbell A, Buschauer R,
Burroughs AM, Berninghausen O, Aravind L, Green R,
Beckmann R, Buskirk AR |
(2022) "Ribosome
collisions induce mRNA cleavage and ribosome rescue in
bacteria." Nature, 603,
503-508. doi: 10.1038/s41586-022-04416-7.
|
Structure of the b. subtilis disome - stalled 70s
ribosome . SNAP
output
|
|
7qh4
|
ribosome |
cryo-EM (5.45 Å) |
Saito K, Kratzat H, Campbell A, Buschauer R,
Burroughs AM, Berninghausen O, Aravind L, Green R,
Beckmann R, Buskirk AR |
(2022) "Ribosome
collisions induce mRNA cleavage and ribosome rescue in
bacteria." Nature, 603,
503-508. doi: 10.1038/s41586-022-04416-7.
|
Structure of the b. subtilis disome - collided 70s
ribosome . SNAP
output
|
|
7qh6
|
ribosome |
cryo-EM (3.08 Å) |
Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A,
Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan
A, Firth AE, Andrews B, Whitworth AJ, Schwartz S, Warren
AJ, Minczuk M |
(2022) "A
late-stage assembly checkpoint of the human
mitochondrial ribosome large subunit." Nat
Commun, 13, 929. doi: 10.1038/s41467-022-28503-5.
|
cryo-EM structure of the human mtlsu assembly
intermediate upon mrm2 depletion - class 1 . SNAP output
|
|
7qh7
|
ribosome |
cryo-EM (2.89 Å) |
Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A,
Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan
A, Firth AE, Andrews B, Whitworth AJ, Schwartz S, Warren
AJ, Minczuk M |
(2022) "A
late-stage assembly checkpoint of the human
mitochondrial ribosome large subunit." Nat
Commun, 13, 929. doi: 10.1038/s41467-022-28503-5.
|
cryo-EM structure of the human mtlsu assembly
intermediate upon mrm2 depletion - class 4 . SNAP output
|
|
7qi4
|
ribosome |
cryo-EM (2.21 Å) |
Singh V, Itoh Y, Del'Olio S, Hassan A, Naschberger A,
Flygaard RK, Nobe Y, Izumikawa K, Aibara S, Andrell J,
Whitford PC, Barrientos A, Taoka M, Amunts A |
(2024) "Mitoribosome
structure with cofactors and modifications reveals
mechanism of ligand binding and interactions with L1
stalk." Nat Commun, 15,
4272. doi: 10.1038/s41467-024-48163-x.
|
Human mitochondrial ribosome at 2.2 Å resolution (bound
to partly built trnas and mrna) . SNAP output
|
|
7qi5
|
ribosome |
cryo-EM (2.63 Å) |
Singh V, Itoh Y, Del'Olio S, Hassan A, Naschberger A,
Flygaard RK, Nobe Y, Izumikawa K, Aibara S, Andrell J,
Whitford PC, Barrientos A, Taoka M, Amunts A |
(2024) "Mitoribosome
structure with cofactors and modifications reveals
mechanism of ligand binding and interactions with L1
stalk." Nat Commun, 15,
4272. doi: 10.1038/s41467-024-48163-x.
|
Human mitochondrial ribosome in complex with mrna,
a-a-, p-p- and e-e-trnas at 2.63 Å resolution .
SNAP output
|
|
7qi6
|
ribosome |
cryo-EM (2.98 Å) |
Singh V, Itoh Y, Del'Olio S, Hassan A, Naschberger A,
Flygaard RK, Nobe Y, Izumikawa K, Aibara S, Andrell J,
Whitford PC, Barrientos A, Taoka M, Amunts A |
(2024) "Mitoribosome
structure with cofactors and modifications reveals
mechanism of ligand binding and interactions with L1
stalk." Nat Commun, 15,
4272. doi: 10.1038/s41467-024-48163-x.
|
Human mitochondrial ribosome in complex with mrna, a-p-
and p-e-trnas at 2.98 Å resolution . SNAP output
|
|
7qiw
|
ribosome |
cryo-EM (2.35 Å) |
Cottilli P, Itoh Y, Nobe Y, Petrov AS, Lison P, Taoka
M, Amunts A |
(2022) "Cryo-EM
structure and rRNA modification sites of a plant
ribosome." Plant Commun.,
3, 100342. doi: 10.1016/j.xplc.2022.100342.
|
Specific features and methylation sites of a plant
ribosome. 60s ribosomal subunit. . SNAP output
|
|
7qix
|
ribosome |
cryo-EM (2.53 Å) |
Cottilli P, Itoh Y, Nobe Y, Petrov AS, Lison P, Taoka
M, Amunts A |
(2022) "Cryo-EM
structure and rRNA modification sites of a plant
ribosome." Plant Commun.,
3, 100342. doi: 10.1016/j.xplc.2022.100342.
|
Specific features and methylation sites of a plant
ribosome. 40s body ribosomal subunit. . SNAP output
|
|
7qiy
|
ribosome |
cryo-EM (2.58 Å) |
Cottilli P, Itoh Y, Nobe Y, Petrov AS, Lison P, Taoka
M, Amunts A |
(2022) "Cryo-EM
structure and rRNA modification sites of a plant
ribosome." Plant Commun.,
3, 100342. doi: 10.1016/j.xplc.2022.100342.
|
Specific features and methylation sites of a plant
ribosome. 40s head ribosomal subunit. . SNAP output
|
|
7qiz
|
ribosome |
cryo-EM (2.38 Å) |
Cottilli P, Itoh Y, Nobe Y, Petrov AS, Lison P, Taoka
M, Amunts A |
(2022) "Cryo-EM
structure and rRNA modification sites of a plant
ribosome." Plant Commun.,
3, 100342. doi: 10.1016/j.xplc.2022.100342.
|
Specific features and methylation sites of a plant 80s
ribosome . SNAP
output
|
|
7qq3
|
ribosome |
cryo-EM (2.1 Å) |
Koller TO, Scheid U, Kosel T, Herrmann J, Krug D,
Boshoff HIM, Beckert B, Evans JC, Schlemmer J, Sloan B,
Weiner DM, Via LE, Moosa A, Ioerger TR, Graf M, Zinshteyn
B, Abdelshahid M, Nguyen F, Arenz S, Gille F, Siebke M,
Seedorf T, Plettenburg O, Green R, Warnke AL, Ullrich J,
Warrass R, Barry 3rd CE, Warner DF, Mizrahi V, Kirschning
A, Wilson DN, Muller R |
(2023) "The
Myxobacterial Antibiotic Myxovalargin: Biosynthesis,
Structural Revision, Total Synthesis, and Molecular
Characterization of Ribosomal Inhibition."
J.Am.Chem.Soc., 145, 851-863.
doi: 10.1021/jacs.2c08816.
|
cryo-EM structure of the e.coli 50s ribosomal subunit
in complex with the antibiotic myxovalargin a. .
SNAP output
|
|
7qqk
|
signaling protein |
cryo-EM (3.8 Å) |
Hogrel G, Guild A, Graham S, Rickman H, Gruschow S,
Bertrand Q, Spagnolo L, White MF |
(2022) "Cyclic
nucleotide-induced helical structure activates a TIR
immune effector." Nature,
608, 808-812. doi: 10.1038/s41586-022-05070-9.
|
Tir-saved effector bound to ca3 . SNAP output
|
|
7qr3
|
RNA |
X-ray (2.18 Å) |
Przytula-Mally AI, Engilberge S, Johannsen S, Olieric
V, Masquida B, Sigel RK |
(2022) "Anticodon-like loop-mediated dimerization in
the crystal structures of HdV-like CPEB3 ribozymes."
Biorxiv. doi: 10.1101/2022.09.22.508989.
|
Chimpanzee cpeb3 hdv-like ribozyme . SNAP output
|
|
7qr4
|
RNA |
X-ray (2.83 Å) |
Przytula-Mally AI, Engilberge S, Johannsen S, Olieric
V, Masquida B, Sigel RK |
(2022) "Anticodon-like loop-mediated dimerization in
the crystal structures of HdV-like CPEB3 ribozymes."
Biorxiv. doi: 10.1101/2022.09.22.508989.
|
Human cpeb3 hdv-like ribozyme . SNAP output
|
|
7qtl
|
viral protein |
cryo-EM (2.48 Å) |
Kouba T, Dubankova A, Drncova P, Donati E, Vidossich
P, Speranzini V, Pflug A, Huchting J, Meier C, De Vivo M,
Cusack S |
(2023) "Direct
observation of backtracking by influenza A and B
polymerases upon consecutive incorporation of the
nucleoside analog T1106." Cell Rep,
42, 111901. doi: 10.1016/j.celrep.2022.111901.
|
Influenza a-h7n9 polymerase elongation complex .
SNAP output
|
|
7qtt
|
splicing |
cryo-EM (3.1 Å) |
Schmitzova J, Cretu C, Dienemann C, Urlaub H, Pena
V |
(2023) "Structural
basis of catalytic activation in human splicing."
Nature, 617, 842-850. doi:
10.1038/s41586-023-06049-w.
|
Structural organization of a late activated human
spliceosome (baqr, core region) . SNAP output
|
|
7qv1
|
ribosome |
cryo-EM (3.5 Å) |
Cerullo F, Filbeck S, Patil PR, Hung HC, Xu H,
Vornberger J, Hofer FW, Schmitt J, Kramer G, Bukau B,
Hofmann K, Pfeffer S, Joazeiro CAP |
(2022) "Bacterial
ribosome collision sensing by a MutS DNA repair ATPase
paralogue." Nature, 603,
509-514. doi: 10.1038/s41586-022-04487-6.
|
Bacillus subtilis collided disome (leading 70s) .
SNAP output
|
|
7qv2
|
ribosome |
cryo-EM (3.5 Å) |
Cerullo F, Filbeck S, Patil PR, Hung HC, Xu H,
Vornberger J, Hofer FW, Schmitt J, Kramer G, Bukau B,
Hofmann K, Pfeffer S, Joazeiro CAP |
(2022) "Bacterial
ribosome collision sensing by a MutS DNA repair ATPase
paralogue." Nature, 603,
509-514. doi: 10.1038/s41586-022-04487-6.
|
Bacillus subtilis collided disome (collided 70s) .
SNAP output
|
|
7qv3
|
ribosome |
cryo-EM (5.14 Å) |
Cerullo F, Filbeck S, Patil PR, Hung HC, Xu H,
Vornberger J, Hofer FW, Schmitt J, Kramer G, Bukau B,
Hofmann K, Pfeffer S, Joazeiro CAP |
(2022) "Bacterial
ribosome collision sensing by a MutS DNA repair ATPase
paralogue." Nature, 603,
509-514. doi: 10.1038/s41586-022-04487-6.
|
Bacillus subtilis muts2-collided disome complex (muts2
conf.2; leading 70s) . SNAP output
|
|
7qvp
|
translation |
cryo-EM (3.0 Å) |
Narita M, Denk T, Matsuo Y, Sugiyama T, Kikuguchi C,
Ito S, Sato N, Suzuki T, Hashimoto S, Machova I, Tesina
P, Beckmann R, Inada T |
(2022) "A
distinct mammalian disome collision interface harbors
K63-linked polyubiquitination of uS10 to trigger
hRQT-mediated subunit dissociation." Nat
Commun, 13, 6411. doi: 10.1038/s41467-022-34097-9.
|
Human collided disome (di-ribosome) stalled on xbp1
mrna . SNAP output
|
|
7qwq
|
ribosome |
cryo-EM (2.83 Å) |
Jomaa A, Gamerdinger M, Hsieh HH, Wallisch A,
Chandrasekaran V, Ulusoy Z, Scaiola A, Hegde RS, Shan SO,
Ban N, Deuerling E |
(2022) "Mechanism
of signal sequence handover from NAC to SRP on
ribosomes during ER-protein targeting."
Science, 375, 839-844. doi:
10.1126/science.abl6459.
|
Ternary complex of ribosome nascent chain with srp and
nac . SNAP output
|
|
7qwr
|
ribosome |
cryo-EM (2.9 Å) |
Jomaa A, Gamerdinger M, Hsieh HH, Wallisch A,
Chandrasekaran V, Ulusoy Z, Scaiola A, Hegde RS, Shan SO,
Ban N, Deuerling E |
(2022) "Mechanism
of signal sequence handover from NAC to SRP on
ribosomes during ER-protein targeting."
Science, 375, 839-844. doi:
10.1126/science.abl6459.
|
Structure of the ribosome-nascent chain containing an
er signal sequence in complex with nac . SNAP output
|
|
7qws
|
ribosome |
cryo-EM (3.4 Å) |
Jomaa A, Gamerdinger M, Hsieh HH, Wallisch A,
Chandrasekaran V, Ulusoy Z, Scaiola A, Hegde RS, Shan SO,
Ban N, Deuerling E |
(2022) "Mechanism
of signal sequence handover from NAC to SRP on
ribosomes during ER-protein targeting."
Science, 375, 839-844. doi:
10.1126/science.abl6459.
|
Structure of ribosome translating beta-tubulin in
complex with ttc5 and nac . SNAP output
|
|
7r0e
|
viral protein |
cryo-EM (2.51 Å) |
Kouba T, Dubankova A, Drncova P, Donati E, Vidossich
P, Speranzini V, Pflug A, Huchting J, Meier C, De Vivo M,
Cusack S |
(2023) "Direct
observation of backtracking by influenza A and B
polymerases upon consecutive incorporation of the
nucleoside analog T1106." Cell Rep,
42, 111901. doi: 10.1016/j.celrep.2022.111901.
|
Early transcription elongation state of influenza
a-h7n9 polymerase backtracked due to double
incoproation of nucleotide analogue t1106 and with
singly incoporated t1106 at the +1 position . SNAP output
|
|
7r1f
|
viral protein |
cryo-EM (2.58 Å) |
Kouba T, Dubankova A, Drncova P, Donati E, Vidossich
P, Speranzini V, Pflug A, Huchting J, Meier C, De Vivo M,
Cusack S |
(2023) "Direct
observation of backtracking by influenza A and B
polymerases upon consecutive incorporation of the
nucleoside analog T1106." Cell Rep,
42, 111901. doi: 10.1016/j.celrep.2022.111901.
|
Early transcription elongation state of influenza b
polymerase backtracked due to double incoproation of
nucleotide analogue t1106 . SNAP output
|
|
7r21
|
antiviral protein |
cryo-EM (3.1 Å) |
Ni D, Hu C, Nam KH, Terns M, Stahlberg H, Ke A |
"Structural snapshots for an atypic type I CRISPR-Cas
system." |
Elongated cascade complex from type i-a crispr-cas
system . SNAP output
|
|
7r4x
|
ribosome |
cryo-EM (2.15 Å) |
Pellegrino S, Dent KC, Spikes T, Warren AJ |
(2023) "Cryo-EM
reconstruction of the human 40S ribosomal subunit at
2.15 angstrom resolution." Nucleic Acids
Res., 51, 4043-4054. doi:
10.1093/nar/gkad194.
|
cryo-EM reconstruction of the human 40s ribosomal
subunit - full map . SNAP output
|
|
7r6k
|
ribosome |
cryo-EM (3.17 Å) |
Cruz VE, Sekulski K, Peddada N, Sailer C,
Balasubramanian S, Weirich CS, Stengel F, Erzberger
JP |
(2022) "Sequence-specific
remodeling of a topologically complex RNP substrate by
Spb4." Nat.Struct.Mol.Biol.,
29, 1228-1238. doi: 10.1038/s41594-022-00874-9.
|
State e2 nucleolar 60s ribosomal intermediate - model
for noc2-noc3 region . SNAP output
|
|
7r6q
|
ribosome |
cryo-EM (2.98 Å) |
Cruz VE, Sekulski K, Peddada N, Sailer C,
Balasubramanian S, Weirich CS, Stengel F, Erzberger
JP |
(2022) "Sequence-specific
remodeling of a topologically complex RNP substrate by
Spb4." Nat.Struct.Mol.Biol.,
29, 1228-1238. doi: 10.1038/s41594-022-00874-9.
|
State e2 nucleolar 60s ribosome biogenesis intermediate
- foot region model . SNAP output
|
|
7r72
|
ribosome |
cryo-EM (3.07 Å) |
Cruz VE, Sekulski K, Peddada N, Sailer C,
Balasubramanian S, Weirich CS, Stengel F, Erzberger
JP |
(2022) "Sequence-specific
remodeling of a topologically complex RNP substrate by
Spb4." Nat.Struct.Mol.Biol.,
29, 1228-1238. doi: 10.1038/s41594-022-00874-9.
|
State e1 nucleolar 60s ribosome biogenesis intermediate
- spb4 local model . SNAP output
|
|
7r7a
|
ribosome |
cryo-EM (3.04 Å) |
Cruz VE, Sekulski K, Peddada N, Sailer C,
Balasubramanian S, Weirich CS, Stengel F, Erzberger
JP |
(2022) "Sequence-specific
remodeling of a topologically complex RNP substrate by
Spb4." Nat.Struct.Mol.Biol.,
29, 1228-1238. doi: 10.1038/s41594-022-00874-9.
|
State e1 nucleolar 60s ribosome biogenesis intermediate
- composite model . SNAP
output
|
|
7r7c
|
ribosome |
cryo-EM (3.71 Å) |
Cruz VE, Sekulski K, Peddada N, Sailer C,
Balasubramanian S, Weirich CS, Stengel F, Erzberger
JP |
(2022) "Sequence-specific
remodeling of a topologically complex RNP substrate by
Spb4." Nat.Struct.Mol.Biol.,
29, 1228-1238. doi: 10.1038/s41594-022-00874-9.
|
State e2 nucleolar 60s ribosomal biogenesis
intermediate - l1 stalk local model . SNAP output
|
|
7r81
|
translation |
cryo-EM (2.7 Å) |
Shen L, Su Z, Yang K, Wu C, Becker T, Bell-Pedersen
D, Zhang J, Sachs MS |
(2021) "Structure
of the translating Neurospora ribosome arrested by
cycloheximide." Proc.Natl.Acad.Sci.USA,
118. doi: 10.1073/pnas.2111862118.
|
Structure of the translating neurospora crassa ribosome
arrested by cycloheximide . SNAP output
|
|
7r97
|
hydrolase-RNA |
X-ray (1.804 Å) |
Dharavath S, Shaw GX, Ji X |
(2022) "Structural
basis for Dicer-like function of an engineered RNase
III variant and insights into the reaction trajectory
of two-Mg 2+ -ion catalysis." Rna Biol.,
19, 908-915. doi: 10.1080/15476286.2022.2099650.
|
Crystal structure of postcleavge complex of escherichia
coli rnase iii . SNAP
output
|
|
7r9f
|
RNA binding protein-RNA |
X-ray (2.89 Å) |
Grunberg S, Doyle LA, Wolf EJ, Dai N, Correa Jr IR,
Yigit E, Stoddard BL |
(2023) "The
structural basis of mRNA recognition and binding by
yeast pseudouridine synthase PUS1." Plos
One, 18, e0291267. doi: 10.1371/journal.pone.0291267.
|
Wild-type yeast pseudouridine synthase, pus1, bound to
5-fluorouracil RNA . SNAP output
|
|
7r9g
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Grunberg S, Doyle LA, Wolf EJ, Dai N, Correa Jr IR,
Yigit E, Stoddard BL |
(2023) "The
structural basis of mRNA recognition and binding by
yeast pseudouridine synthase PUS1." Plos
One, 18, e0291267. doi: 10.1371/journal.pone.0291267.
|
Catalytically inactive yeast pseudouridine synthase,
pus1, bound to RNA . SNAP output
|
|
7rdx
|
replication-transcription |
cryo-EM (3.1 Å) |
Chen J, Wang Q, Malone B, Llewellyn E, Pechersky Y,
Maruthi K, Eng ET, Perry JK, Campbell EA, Shaw DE, Darst
SA |
(2022) "Ensemble
cryo-EM reveals conformational states of the nsp13
helicase in the SARS-CoV-2 helicase
replication-transcription complex."
Nat.Struct.Mol.Biol., 29,
250-260. doi: 10.1038/s41594-022-00734-6.
|
Sars-cov-2 replication-transcription complex bound to
nsp13 helicase - nsp13(2)-rtc - open class . SNAP output
|
|
7rdy
|
replication-transcription |
cryo-EM (3.1 Å) |
Chen J, Wang Q, Malone B, Llewellyn E, Pechersky Y,
Maruthi K, Eng ET, Perry JK, Campbell EA, Shaw DE, Darst
SA |
(2022) "Ensemble
cryo-EM reveals conformational states of the nsp13
helicase in the SARS-CoV-2 helicase
replication-transcription complex."
Nat.Struct.Mol.Biol., 29,
250-260. doi: 10.1038/s41594-022-00734-6.
|
Sars-cov-2 replication-transcription complex bound to
nsp13 helicase - nsp13(2)-rtc - engaged class .
SNAP output
|
|
7rdz
|
replication-transcription |
cryo-EM (3.6 Å) |
Chen J, Wang Q, Malone B, Llewellyn E, Pechersky Y,
Maruthi K, Eng ET, Perry JK, Campbell EA, Shaw DE, Darst
SA |
(2022) "Ensemble
cryo-EM reveals conformational states of the nsp13
helicase in the SARS-CoV-2 helicase
replication-transcription complex."
Nat.Struct.Mol.Biol., 29,
250-260. doi: 10.1038/s41594-022-00734-6.
|
Sars-cov-2 replication-transcription complex bound to
nsp13 helicase - nsp13(2)-rtc - apo class . SNAP output
|
|
7re0
|
replication-transcription |
cryo-EM (3.5 Å) |
Chen J, Wang Q, Malone B, Llewellyn E, Pechersky Y,
Maruthi K, Eng ET, Perry JK, Campbell EA, Shaw DE, Darst
SA |
(2022) "Ensemble
cryo-EM reveals conformational states of the nsp13
helicase in the SARS-CoV-2 helicase
replication-transcription complex."
Nat.Struct.Mol.Biol., 29,
250-260. doi: 10.1038/s41594-022-00734-6.
|
Sars-cov-2 replication-transcription complex bound to
nsp13 helicase - nsp13(2)-rtc - swiveled class .
SNAP output
|
|
7re1
|
replication-transcription |
cryo-EM (2.91 Å) |
Chen J, Wang Q, Malone B, Llewellyn E, Pechersky Y,
Maruthi K, Eng ET, Perry JK, Campbell EA, Shaw DE, Darst
SA |
(2022) "Ensemble
cryo-EM reveals conformational states of the nsp13
helicase in the SARS-CoV-2 helicase
replication-transcription complex."
Nat.Struct.Mol.Biol., 29,
250-260. doi: 10.1038/s41594-022-00734-6.
|
Sars-cov-2 replication-transcription complex bound to
nsp13 helicase - nsp13(2)-rtc (composite) . SNAP output
|
|
7re2
|
replication-transcription |
cryo-EM (3.17 Å) |
Chen J, Wang Q, Malone B, Llewellyn E, Pechersky Y,
Maruthi K, Eng ET, Perry JK, Campbell EA, Shaw DE, Darst
SA |
(2022) "Ensemble
cryo-EM reveals conformational states of the nsp13
helicase in the SARS-CoV-2 helicase
replication-transcription complex."
Nat.Struct.Mol.Biol., 29,
250-260. doi: 10.1038/s41594-022-00734-6.
|
Sars-cov-2 replication-transcription complex bound to
nsp13 helicase - nsp13(1)-rtc . SNAP output
|
|
7re3
|
replication-transcription |
cryo-EM (3.33 Å) |
Chen J, Wang Q, Malone B, Llewellyn E, Pechersky Y,
Maruthi K, Eng ET, Perry JK, Campbell EA, Shaw DE, Darst
SA |
(2022) "Ensemble
cryo-EM reveals conformational states of the nsp13
helicase in the SARS-CoV-2 helicase
replication-transcription complex."
Nat.Struct.Mol.Biol., 29,
250-260. doi: 10.1038/s41594-022-00734-6.
|
Sars-cov-2 replication-transcription complex bound to
nsp13 helicase - nsp13(2)-rtc dimer . SNAP output
|
|
7rgu
|
RNA binding protein-RNA |
X-ray (3.2 Å) |
Kim HJ, Black M, Edwards RA, Peillard-Fiorente F,
Panigrahi R, Klingler D, Eidelpes R, Zeindl R, Peng S, Su
J, Omar AR, MacMillan AM, Kreutz C, Tollinger M,
Charpentier X, Attaiech L, Glover JNM |
(2022) "Structural
basis for recognition of transcriptional terminator
structures by ProQ/FinO domain RNA chaperones."
Nat Commun, 13, 7076. doi:
10.1038/s41467-022-34875-5.
|
The crystal structure of rocc bound to a
transcriptional terminator . SNAP output
|
|
7rq8
|
ribosome-RNA |
X-ray (2.5 Å) |
Mitcheltree MJ, Pisipati A, Syroegin EA, Silvestre
KJ, Klepacki D, Mason JD, Terwilliger DW, Testolin G,
Pote AR, Wu KJY, Ladley RP, Chatman K, Mankin AS,
Polikanov YS, Myers AG |
(2021) "A
synthetic antibiotic class overcoming bacterial
multidrug resistance." Nature,
599, 507-512. doi: 10.1038/s41586-021-04045-6.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with iboxamycin, mrna,
deacylated a- and e-site trnas, and aminoacylated
p-site trna at 2.50a resolution . SNAP output
|
|
7rq9
|
ribosome-RNA |
X-ray (2.6 Å) |
Mitcheltree MJ, Pisipati A, Syroegin EA, Silvestre
KJ, Klepacki D, Mason JD, Terwilliger DW, Testolin G,
Pote AR, Wu KJY, Ladley RP, Chatman K, Mankin AS,
Polikanov YS, Myers AG |
(2021) "A
synthetic antibiotic class overcoming bacterial
multidrug resistance." Nature,
599, 507-512. doi: 10.1038/s41586-021-04045-6.
|
Crystal structure of the a2058-dimethylated thermus
thermophilus 70s ribosome in complex with iboxamycin,
mrna, deacylated a- and e-site trnas, and aminoacylated
p-site trna at 2.60a resolution . SNAP output
|
|
7rqa
|
ribosome |
X-ray (2.4 Å) |
Syroegin EA, Flemmich L, Klepacki D, Vazquez-Laslop
N, Micura R, Polikanov YS |
(2022) "Structural
basis for the context-specific action of the classic
peptidyl transferase inhibitor chloramphenicol."
Nat.Struct.Mol.Biol., 29,
152-161. doi: 10.1038/s41594-022-00720-y.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, a-site
aminoacyl-trna analog acc-pmn, and p-site
mti-tripeptidyl-trna analog acca-itm at 2.40a
resolution . SNAP
output
|
|
7rqb
|
ribosome |
X-ray (2.45 Å) |
Syroegin EA, Flemmich L, Klepacki D, Vazquez-Laslop
N, Micura R, Polikanov YS |
(2022) "Structural
basis for the context-specific action of the classic
peptidyl transferase inhibitor chloramphenicol."
Nat.Struct.Mol.Biol., 29,
152-161. doi: 10.1038/s41594-022-00720-y.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, a-site
aminoacyl-trna analog acc-pmn, and p-site
mai-tripeptidyl-trna analog acca-iam at 2.45a
resolution . SNAP
output
|
|
7rqc
|
ribosome |
X-ray (2.5 Å) |
Syroegin EA, Flemmich L, Klepacki D, Vazquez-Laslop
N, Micura R, Polikanov YS |
(2022) "Structural
basis for the context-specific action of the classic
peptidyl transferase inhibitor chloramphenicol."
Nat.Struct.Mol.Biol., 29,
152-161. doi: 10.1038/s41594-022-00720-y.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, a-site
aminoacyl-trna analog acc-pmn, and p-site
mfi-tripeptidyl-trna analog acca-ifm at 2.50a
resolution . SNAP
output
|
|
7rqd
|
ribosome |
X-ray (2.5 Å) |
Syroegin EA, Flemmich L, Klepacki D, Vazquez-Laslop
N, Micura R, Polikanov YS |
(2022) "Structural
basis for the context-specific action of the classic
peptidyl transferase inhibitor chloramphenicol."
Nat.Struct.Mol.Biol., 29,
152-161. doi: 10.1038/s41594-022-00720-y.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, a-site deacylated
trna analog cacca, p-site mti-tripeptidyl-trna analog
acca-itm, and chloramphenicol at 2.50a resolution .
SNAP output
|
|
7rqe
|
ribosome |
X-ray (2.4 Å) |
Syroegin EA, Flemmich L, Klepacki D, Vazquez-Laslop
N, Micura R, Polikanov YS |
(2022) "Structural
basis for the context-specific action of the classic
peptidyl transferase inhibitor chloramphenicol."
Nat.Struct.Mol.Biol., 29,
152-161. doi: 10.1038/s41594-022-00720-y.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, a-site deacylated
trna analog cacca, p-site mai-tripeptidyl-trna analog
acca-iam, and chloramphenicol at 2.40a resolution .
SNAP output
|
|
7rr5
|
ribosome |
cryo-EM (3.23 Å) |
Zeng F, Li X, Pires-Alves M, Chen X, Hawk CW, Jin
H |
(2021) "Conserved
heterodimeric GTPase Rbg1/Tma46 promotes efficient
translation in eukaryotic cells." Cell
Rep, 37, 109877. doi: 10.1016/j.celrep.2021.109877.
|
Structure of ribosomal complex bound with rbg1-tma46 .
SNAP output
|
|
7ryf
|
ribosome-RNA |
cryo-EM (2.65 Å) |
Morgan CE, Zhang Z, Bonomo RA, Yu EW |
(2022) "An
Analysis of the Novel Fluorocycline TP-6076 Bound to
Both the Ribosome and Multidrug Efflux Pump AdeJ from
Acinetobacter baumannii." Mbio,
13, e0373221. doi: 10.1128/mbio.03732-21.
|
A. baumannii ribosome-tp-6076 complex: p-site trna 70s
. SNAP output
|
|
7ryg
|
ribosome-RNA |
cryo-EM (2.38 Å) |
Morgan CE, Zhang Z, Bonomo RA, Yu EW |
(2022) "An
Analysis of the Novel Fluorocycline TP-6076 Bound to
Both the Ribosome and Multidrug Efflux Pump AdeJ from
Acinetobacter baumannii." Mbio,
13, e0373221. doi: 10.1128/mbio.03732-21.
|
A. baumannii ribosome-tp-6076 complex: e-site trna 70s
. SNAP output
|
|
7ryh
|
ribosome-RNA |
cryo-EM (2.43 Å) |
Morgan CE, Zhang Z, Bonomo RA, Yu EW |
(2022) "An
Analysis of the Novel Fluorocycline TP-6076 Bound to
Both the Ribosome and Multidrug Efflux Pump AdeJ from
Acinetobacter baumannii." Mbio,
13, e0373221. doi: 10.1128/mbio.03732-21.
|
A. baumannii ribosome-tp-6076 complex: empty 70s .
SNAP output
|
|
7rzz
|
RNA binding protein |
X-ray (2.39 Å) |
Qiu C, Wine RN, Campbell ZT, Hall TMT |
(2022) "Bipartite
interaction sites differentially modulate RNA-binding
affinity of a protein complex essential for germline
stem cell self-renewal." Nucleic Acids
Res., 50, 536-548. doi: 10.1093/nar/gkab1220.
|
Crystal structure of fbf-2 in complex with lst-1 site a
peptide and compact fbe RNA . SNAP output
|
|
7s02
|
RNA binding protein |
X-ray (2.34 Å) |
Qiu C, Wine RN, Campbell ZT, Hall TMT |
(2022) "Bipartite
interaction sites differentially modulate RNA-binding
affinity of a protein complex essential for germline
stem cell self-renewal." Nucleic Acids
Res., 50, 536-548. doi: 10.1093/nar/gkab1220.
|
Crystal structure of fbf-2 in complex with lst-1 site a
peptide and fbe RNA . SNAP output
|
|
7s0s
|
ribosome |
cryo-EM (3.05 Å) |
Laughlin ZT, Nandi S, Dey D, Zelinskaya N, Witek MA,
Srinivas P, Nguyen HA, Kuiper EG, Comstock LR, Dunham CM,
Conn GL |
(2022) "50S
subunit recognition and modification by the
Mycobacterium tuberculosis ribosomal RNA
methyltransferase TlyA."
Proc.Natl.Acad.Sci.USA, 119,
e2120352119. doi: 10.1073/pnas.2120352119.
|
M. tuberculosis ribosomal RNA methyltransferase tlya
bound to m. smegmatis 50s ribosomal subunit . SNAP output
|
|
7s1g
|
ribosome-antibiotic |
cryo-EM (2.48 Å) |
Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T,
Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS,
Fujimori DG |
(2022) "Structural
basis for context-specific inhibition of translation by
oxazolidinone antibiotics."
Nat.Struct.Mol.Biol., 29,
162-171. doi: 10.1038/s41594-022-00723-9.
|
Wild-type escherichia coli stalled ribosome with
antibiotic linezolid . SNAP output
|
|
7s1h
|
ribosome-antibiotic |
cryo-EM (2.35 Å) |
Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T,
Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS,
Fujimori DG |
(2022) "Structural
basis for context-specific inhibition of translation by
oxazolidinone antibiotics."
Nat.Struct.Mol.Biol., 29,
162-171. doi: 10.1038/s41594-022-00723-9.
|
Wild-type escherichia coli ribosome with antibiotic
linezolid . SNAP
output
|
|
7s1i
|
ribosome |
cryo-EM (2.48 Å) |
Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T,
Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS,
Fujimori DG |
(2022) "Structural
basis for context-specific inhibition of translation by
oxazolidinone antibiotics."
Nat.Struct.Mol.Biol., 29,
162-171. doi: 10.1038/s41594-022-00723-9.
|
Wild-type escherichia coli stalled ribosome with
antibiotic radezolid . SNAP output
|
|
7s1j
|
ribosome |
cryo-EM (2.47 Å) |
Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T,
Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS,
Fujimori DG |
(2022) "Structural
basis for context-specific inhibition of translation by
oxazolidinone antibiotics."
Nat.Struct.Mol.Biol., 29,
162-171. doi: 10.1038/s41594-022-00723-9.
|
Wild-type escherichia coli ribosome with antibiotic
radezolid . SNAP
output
|
|
7s1k
|
ribosome |
cryo-EM (2.42 Å) |
Tsai K, Stojkovic V, Lee DJ, Young ID, Szal T,
Klepacki D, Vazquez-Laslop N, Mankin AS, Fraser JS,
Fujimori DG |
(2022) "Structural
basis for context-specific inhibition of translation by
oxazolidinone antibiotics."
Nat.Struct.Mol.Biol., 29,
162-171. doi: 10.1038/s41594-022-00723-9.
|
Cfr-modified escherichia coli stalled ribosome with
antibiotic radezolid . SNAP output
|
|
7s37
|
hydrolase-RNA |
cryo-EM (3.2 Å) |
Cofsky JC, Soczek KM, Knott GJ, Nogales E, Doudna
JA |
(2022) "CRISPR-Cas9
bends and twists DNA to read its sequence."
Nat.Struct.Mol.Biol., 29,
395-402. doi: 10.1038/s41594-022-00756-0.
|
Cas9:sgrna (s. pyogenes) in the open-protein
conformation . SNAP
output
|
|
7s7b
|
RNA binding protein-RNA |
cryo-EM (4.06 Å) |
Puno MR, Lima CD |
(2022) "Structural
basis for RNA surveillance by the human nuclear exosome
targeting (NEXT) complex." Cell,
185, 2132-2147.e26. doi: 10.1016/j.cell.2022.04.016.
|
Human nuclear exosome targeting (next) complex
homodimer bound to RNA (substrate 1) . SNAP output
|
|
7s7c
|
RNA binding protein-RNA |
cryo-EM (3.62 Å) |
Puno MR, Lima CD |
(2022) "Structural
basis for RNA surveillance by the human nuclear exosome
targeting (NEXT) complex." Cell,
185, 2132-2147.e26. doi: 10.1016/j.cell.2022.04.016.
|
Human nuclear exosome targeting (next) complex bound to
RNA (substrate 2) . SNAP
output
|
|
7s9u
|
ribosome |
cryo-EM (3.2 Å) |
Seffouh A, Trahan C, Wasi T, Jain N, Basu K, Britton
RA, Oeffinger M, Ortega J |
(2022) "RbgA
ensures the correct timing in the maturation of the 50S
subunits functional sites." Nucleic Acids
Res., 50, 10801-10816. doi:
10.1093/nar/gkac059.
|
44sr3c ribosomal particle . SNAP output
|
|
7sa4
|
ribosome |
cryo-EM (2.55 Å) |
Tian Y, Zeng F, Raybarman A, Fatma S, Carruthers A,
Li Q, Huang RH |
(2022) "Sequential
rescue and repair of stalled and damaged ribosome by
bacterial PrfH and RtcB."
Proc.Natl.Acad.Sci.USA, 119,
e2202464119. doi: 10.1073/pnas.2202464119.
|
Damaged 70s ribosome with prfh bound . SNAP output
|
|
7sae
|
ribosome |
cryo-EM (3.0 Å) |
Seffouh A, Trahan C, Wasi T, Jain N, Basu K, Britton
RA, Oeffinger M, Ortega J |
(2022) "RbgA
ensures the correct timing in the maturation of the 50S
subunits functional sites." Nucleic Acids
Res., 50, 10801-10816. doi:
10.1093/nar/gkac059.
|
44sr70p class1 ribosomal particle . SNAP output
|
|
7sbb
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Schwartz EA, McBride TM, Bravo JPK, Wrapp D, Fineran
PC, Fagerlund RD, Taylor DW |
(2022) "Structural
rearrangements allow nucleic acid discrimination by
type I-D Cascade." Nat Commun,
13, 2829. doi: 10.1038/s41467-022-30402-8.
|
Structure of type i-d cascade bound to a ssrna target .
SNAP output
|
|
7sc6
|
RNA binding protein-RNA |
cryo-EM (5.51 Å) |
Bonilla SL, Sherlock ME, MacFadden A, Kieft JS |
(2021) "A viral
RNA hijacks host machinery using dynamic conformational
changes of a tRNA-like structure."
Science, 374, 955-960. doi:
10.1126/science.abe8526.
|
Trna-like structure from brome mosaic virus bound to
tyrosyl-trna synthetase from phaseolus vulgaris.
conformation: bound state 1. . SNAP output
|
|
7scq
|
RNA binding protein-RNA |
cryo-EM (6.0 Å) |
Bonilla SL, Sherlock ME, MacFadden A, Kieft JS |
(2021) "A viral
RNA hijacks host machinery using dynamic conformational
changes of a tRNA-like structure."
Science, 374, 955-960. doi:
10.1126/science.abe8526.
|
Trna-like structure from brome mosaic virus bound to
tyrosyl-trna synthetase from phaseolus vulgaris.
conformation: bound state 2. . SNAP output
|
|
7sfr
|
ribosome-antibiotic |
cryo-EM (2.6 Å) |
Zhang J, Lair C, Roubert C, Amaning K, Barrio MB,
Benedetti Y, Cui Z, Xing Z, Li X, Franzblau SG, Baurin N,
Bordon-Pallier F, Cantalloube C, Sans S, Silve S, Blanc
I, Fraisse L, Rak A, Jenner LB, Yusupova G, Yusupov M,
Zhang J, Kaneko T, Yang TJ, Fotouhi N, Nuermberger E,
Tyagi S, Betoudji F, Upton A, Sacchettini JC, Lagrange
S |
(2023) "Discovery
of natural-product-derived sequanamycins as potent oral
anti-tuberculosis agents." Cell,
186, 1013. doi: 10.1016/j.cell.2023.01.043.
|
Unmethylated mtb ribosome 50s with seq-9 . SNAP output
|
|
7slp
|
RNA binding protein-RNA |
cryo-EM (4.1 Å) |
Yang Y, Liu S, Egloff S, Eichhorn CD, Hadjian T, Zhen
J, Kiss T, Zhou ZH, Feigon J |
(2022) "Structural
basis of RNA conformational switching in the
transcriptional regulator 7SK RNP."
Mol.Cell, 82, 1724. doi:
10.1016/j.molcel.2022.03.001.
|
cryo-EM structure of 7sk core rnp with linear RNA .
SNAP output
|
|
7slq
|
RNA binding protein-RNA |
cryo-EM (3.7 Å) |
Yang Y, Liu S, Egloff S, Eichhorn CD, Hadjian T, Zhen
J, Kiss T, Zhou ZH, Feigon J |
(2022) "Structural
basis of RNA conformational switching in the
transcriptional regulator 7SK RNP."
Mol.Cell, 82, 1724. doi:
10.1016/j.molcel.2022.03.001.
|
cryo-EM structure of 7sk core rnp with circular RNA .
SNAP output
|
|
7sop
|
RNA binding protein-RNA |
X-ray (1.55 Å) |
Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules
T, Iben JR, Coon SL, Gaidamakov S, Noronha AM, Wilds CJ,
Maraia RJ, Gehring K |
(2022) "Structural
basis of 3'-end poly(A) RNA recognition by LARP1."
Nucleic Acids Res., 50,
9534-9547. doi: 10.1093/nar/gkac696.
|
Lam domain of human larp1 in complex with aaauaa RNA .
SNAP output
|
|
7soq
|
RNA binding protein-RNA |
X-ray (1.15 Å) |
Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules
T, Iben JR, Coon SL, Gaidamakov S, Noronha AM, Wilds CJ,
Maraia RJ, Gehring K |
(2022) "Structural
basis of 3'-end poly(A) RNA recognition by LARP1."
Nucleic Acids Res., 50,
9534-9547. doi: 10.1093/nar/gkac696.
|
Lam domain of human larp1 in complex with aaa RNA .
SNAP output
|
|
7sor
|
RNA binding protein-RNA |
X-ray (1.35 Å) |
Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules
T, Iben JR, Coon SL, Gaidamakov S, Noronha AM, Wilds CJ,
Maraia RJ, Gehring K |
(2022) "Structural
basis of 3'-end poly(A) RNA recognition by LARP1."
Nucleic Acids Res., 50,
9534-9547. doi: 10.1093/nar/gkac696.
|
Lam domain of human larp1 in complex with aaa RNA .
SNAP output
|
|
7sos
|
RNA binding protein-RNA |
X-ray (1.25 Å) |
Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules
T, Iben JR, Coon SL, Gaidamakov S, Noronha AM, Wilds CJ,
Maraia RJ, Gehring K |
(2022) "Structural
basis of 3'-end poly(A) RNA recognition by LARP1."
Nucleic Acids Res., 50,
9534-9547. doi: 10.1093/nar/gkac696.
|
Lam domain of human larp1 in complex with aaaa RNA .
SNAP output
|
|
7sot
|
RNA binding protein-RNA |
X-ray (1.52 Å) |
Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules
T, Iben JR, Coon SL, Gaidamakov S, Noronha AM, Wilds CJ,
Maraia RJ, Gehring K |
(2022) "Structural
basis of 3'-end poly(A) RNA recognition by LARP1."
Nucleic Acids Res., 50,
9534-9547. doi: 10.1093/nar/gkac696.
|
Lam domain of human larp1 in complex with aaaaaa
oligonucleotide . SNAP
output
|
|
7sou
|
RNA binding protein-RNA |
X-ray (1.45 Å) |
Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules
T, Iben JR, Coon SL, Gaidamakov S, Noronha AM, Wilds CJ,
Maraia RJ, Gehring K |
(2022) "Structural
basis of 3'-end poly(A) RNA recognition by LARP1."
Nucleic Acids Res., 50,
9534-9547. doi: 10.1093/nar/gkac696.
|
Lam domain of human larp1 in complex with aaaaaa
polynucleotide . SNAP
output
|
|
7sov
|
RNA binding protein-RNA |
X-ray (1.45 Å) |
Kozlov G, Mattijssen S, Jiang J, Nyandwi S, Sprules
T, Iben JR, Coon SL, Gaidamakov S, Noronha AM, Wilds CJ,
Maraia RJ, Gehring K |
(2022) "Structural
basis of 3'-end poly(A) RNA recognition by LARP1."
Nucleic Acids Res., 50,
9534-9547. doi: 10.1093/nar/gkac696.
|
Lam domain of human larp1 in complex with aaaaaaaaaaa
RNA polynucleotide . SNAP output
|
|
7sow
|
RNA binding protein-RNA |
X-ray (1.3 Å) |
Kozlov G, Jiang J, Rutherford T, Noronha AM, Wilds
CJ, Gehring K |
(2024) "Enhanced
binding of guanylated poly(A) RNA by the LaM domain of
LARP1." Rna Biol., 21,
7-16. doi: 10.1080/15476286.2024.2379121.
|
Lam domain of human larp1 in complex with uuuuuu .
SNAP output
|
|
7sp1
|
protein fibril-RNA |
cryo-EM (3.4 Å) |
Abskharon R, Sawaya MR, Boyer DR, Cao Q, Nguyen BA,
Cascio D, Eisenberg DS |
(2022) "Cryo-EM
structure of RNA-induced tau fibrils reveals a small
C-terminal core that may nucleate fibril
formation." Proc.Natl.Acad.Sci.USA,
119, e2119952119. doi: 10.1073/pnas.2119952119.
|
RNA-induced tau amyloid fibril . SNAP output
|
|
7ss9
|
ribosome |
cryo-EM (3.9 Å) |
Carbone CE, Loveland AB, Gamper Jr HB, Hou YM, Demo
G, Korostelev AA |
(2021) "Time-resolved
cryo-EM visualizes ribosomal translocation with EF-G
and GTP." Nat Commun, 12,
7236. doi: 10.1038/s41467-021-27415-0.
|
Late translocation intermediate with ef-g partially
dissociated (structure v) . SNAP output
|
|
7ssd
|
ribosome |
cryo-EM (3.3 Å) |
Carbone CE, Loveland AB, Gamper Jr HB, Hou YM, Demo
G, Korostelev AA |
(2021) "Time-resolved
cryo-EM visualizes ribosomal translocation with EF-G
and GTP." Nat Commun, 12,
7236. doi: 10.1038/s41467-021-27415-0.
|
Mid translocation intermediate with ef-g bound with gdp
(structure iv) . SNAP
output
|
|
7ssl
|
ribosome |
cryo-EM (3.8 Å) |
Carbone CE, Loveland AB, Gamper Jr HB, Hou YM, Demo
G, Korostelev AA |
(2021) "Time-resolved
cryo-EM visualizes ribosomal translocation with EF-G
and GTP." Nat Commun, 12,
7236. doi: 10.1038/s41467-021-27415-0.
|
Pre translocation intermediate with ef-g bound to gdp
and pi (structure iii) . SNAP output
|
|
7ssn
|
ribosome |
cryo-EM (3.2 Å) |
Carbone CE, Loveland AB, Gamper Jr HB, Hou YM, Demo
G, Korostelev AA |
(2021) "Time-resolved
cryo-EM visualizes ribosomal translocation with EF-G
and GTP." Nat Commun, 12,
7236. doi: 10.1038/s41467-021-27415-0.
|
Pre translocation 70s ribosome with a-p* and p-e trna
(structure ii-b) . SNAP
output
|
|
7sso
|
ribosome |
cryo-EM (3.2 Å) |
Carbone CE, Loveland AB, Gamper Jr HB, Hou YM, Demo
G, Korostelev AA |
(2021) "Time-resolved
cryo-EM visualizes ribosomal translocation with EF-G
and GTP." Nat Commun, 12,
7236. doi: 10.1038/s41467-021-27415-0.
|
Pre translocation 70s ribosome with a-a and p-e trna
(structure ii-a) . SNAP
output
|
|
7ssw
|
ribosome |
cryo-EM (3.8 Å) |
Carbone CE, Loveland AB, Gamper Jr HB, Hou YM, Demo
G, Korostelev AA |
(2021) "Time-resolved
cryo-EM visualizes ribosomal translocation with EF-G
and GTP." Nat Commun, 12,
7236. doi: 10.1038/s41467-021-27415-0.
|
Late translocation intermediate with ef-g dissociated
(structure vi) . SNAP
output
|
|
7st2
|
ribosome |
cryo-EM (2.9 Å) |
Carbone CE, Loveland AB, Gamper Jr HB, Hou YM, Demo
G, Korostelev AA |
(2021) "Time-resolved
cryo-EM visualizes ribosomal translocation with EF-G
and GTP." Nat Commun, 12,
7236. doi: 10.1038/s41467-021-27415-0.
|
Post translocation, non-rotated 70s ribosome with ef-g
dissociated (structure vii) . SNAP output
|
|
7st6
|
ribosome |
cryo-EM (3.0 Å) |
Carbone CE, Loveland AB, Gamper Jr HB, Hou YM, Demo
G, Korostelev AA |
(2021) "Time-resolved
cryo-EM visualizes ribosomal translocation with EF-G
and GTP." Nat Commun, 12,
7236. doi: 10.1038/s41467-021-27415-0.
|
Pre translocation, non-rotated 70s ribosome (structure
i) . SNAP output
|
|
7st7
|
ribosome-antibiotic |
cryo-EM (3.2 Å) |
Carbone CE, Loveland AB, Gamper Jr HB, Hou YM, Demo
G, Korostelev AA |
(2021) "Time-resolved
cryo-EM visualizes ribosomal translocation with EF-G
and GTP." Nat Commun, 12,
7236. doi: 10.1038/s41467-021-27415-0.
|
Pre translocation intermediate stalled with viomycin
and bound with ef-g in a gdp and pi state (structure
iii-vio) . SNAP
output
|
|
7suk
|
ribosome |
cryo-EM (3.99 Å) |
Zhao Y, Rai J, Xu C, He H, Li H |
(2022) "Artificial
intelligence-assisted cryoEM structure of Bfr2-Lcp5
complex observed in the yeast small subunit
processome." Commun Biol,
5, 523. doi: 10.1038/s42003-022-03500-y.
|
Structure of bfr2-lcp5 complex observed in the small
subunit processome isolated from r2tp-depleted yeast
cells . SNAP output
|
|
7sva
|
gene regulation |
cryo-EM (3.26 Å) |
Xiao Y, Maeda S, Otomo T, MacRae IJ |
(2023) "Structural
basis for RNA slicing by a plant Argonaute."
Nat.Struct.Mol.Biol., 30,
778-784. doi: 10.1038/s41594-023-00989-7.
|
cryo-EM structure of arabidopsis ago10-guide RNA
complex . SNAP
output
|
|
7swf
|
gene regulation |
cryo-EM (3.79 Å) |
Xiao Y, MacRae IJ |
(2022) "The
molecular mechanism of microRNA duplex selectivity of
Arabidopsis ARGONAUTE10." Nucleic Acids
Res., 50, 10041-10052. doi:
10.1093/nar/gkac571.
|
cryo-EM structure of arabidopsis ago10-guide-target RNA
complex in a central duplex conformation . SNAP output
|
|
7swq
|
gene regulation |
cryo-EM (3.79 Å) |
Xiao Y, Maeda S, Otomo T, MacRae IJ |
(2023) "Structural
basis for RNA slicing by a plant Argonaute."
Nat.Struct.Mol.Biol., 30,
778-784. doi: 10.1038/s41594-023-00989-7.
|
cryo-EM structure of arabidopsis ago10-guide-target RNA
complex in a bent duplex conformation . SNAP output
|
|
7syg
|
ribosome |
cryo-EM (4.3 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
"Molecular architecture of 40S initiation complexes
on the Hepatitis C virus IRES: from ribosomal attachment
to eIF5B-mediated reorientation of initiator tRNA." |
Structure of the hcv ires binding to the 40s ribosomal
subunit, closed conformation. structure 1(delta dii) .
SNAP output
|
|
7syh
|
ribosome |
cryo-EM (4.6 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
"Molecular architecture of 40S initiation complexes
on the Hepatitis C virus IRES: from ribosomal attachment
to eIF5B-mediated reorientation of initiator tRNA." |
Structure of the hcv ires binding to the 40s ribosomal
subunit, closed conformation. structure 2(delta dii) .
SNAP output
|
|
7syi
|
ribosome |
cryo-EM (4.5 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the hcv ires binding to the 40s ribosomal
subunit, closed conformation. structure 3(delta dii) .
SNAP output
|
|
7syj
|
ribosome |
cryo-EM (4.8 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the hcv ires binding to the 40s ribosomal
subunit, closed conformation. structure 4(delta dii) .
SNAP output
|
|
7syk
|
ribosome |
cryo-EM (4.2 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the hcv ires binding to the 40s ribosomal
subunit, closed conformation. structure 5(delta dii) .
SNAP output
|
|
7syl
|
ribosome |
cryo-EM (4.5 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the hcv ires bound to the 40s ribosomal
subunit, closed conformation. structure 6(delta dii) .
SNAP output
|
|
7sym
|
ribosome |
cryo-EM (4.8 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
"Comprehensive structural overview of the HCV
IRES-mediated translation initiation pathway." |
Structure of the hcv ires bound to the 40s ribosomal
subunit, head opening. structure 7(delta dii) .
SNAP output
|
|
7syn
|
ribosome |
cryo-EM (4.0 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
"Molecular architecture of 40S initiation complexes
on the Hepatitis C virus IRES: from ribosomal attachment
to eIF5B-mediated reorientation of initiator tRNA." |
Structure of the hcv ires bound to the 40s ribosomal
subunit, head opening. structure 8(delta dii) .
SNAP output
|
|
7syo
|
ribosome |
cryo-EM (4.6 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the hcv ires bound to the 40s ribosomal
subunit, head open. structure 9(delta dii) . SNAP output
|
|
7syp
|
ribosome |
cryo-EM (4.0 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the wt ires and 40s ribosome binary
complex, open conformation. structure 10(wt) . SNAP output
|
|
7syq
|
ribosome |
cryo-EM (3.8 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the wt ires and 40s ribosome ternary
complex, open conformation. structure 11(wt) . SNAP output
|
|
7syr
|
ribosome |
cryo-EM (3.6 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the wt ires eif2-containing 48s initiation
complex, closed conformation. structure 12(wt). .
SNAP output
|
|
7sys
|
ribosome |
cryo-EM (3.5 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the delta dii ires eif2-containing 48s
initiation complex, closed conformation. structure
12(delta dii). . SNAP
output
|
|
7syt
|
ribosome |
cryo-EM (4.4 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the wt ires w-o eif2 48s initiation
complex, closed conformation. structure 13(wt) .
SNAP output
|
|
7syu
|
ribosome |
cryo-EM (4.6 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the delta dii ires w-o eif2 48s initiation
complex, closed conformation. structure 13(delta dii) .
SNAP output
|
|
7syv
|
ribosome |
cryo-EM (3.9 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the wt ires eif5b-containing pre-48s
initiation complex, open conformation. structure 14(wt)
. SNAP output
|
|
7syw
|
ribosome |
cryo-EM (3.7 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the wt ires eif5b-containing 48s
initiation complex, closed conformation. structure
15(wt) . SNAP output
|
|
7syx
|
ribosome |
cryo-EM (3.7 Å) |
Brown ZP, Abaeva IS, De S, Hellen CUT, Pestova TV,
Frank J |
(2022) "Molecular
architecture of 40S translation initiation complexes on
the hepatitis C virus IRES." Embo J.,
41, e110581. doi: 10.15252/embj.2022110581.
|
Structure of the delta dii ires eif5b-containing 48s
initiation complex, closed conformation. structure
15(delta dii) . SNAP
output
|
|
7szu
|
immune system-RNA |
X-ray (2.24 Å) |
Rees HC, Gogacz W, Li NS, Koirala D, Piccirilli
JA |
(2022) "Structural
Basis for Fluorescence Activation by Pepper RNA."
Acs Chem.Biol., 17,
1866-1875. doi: 10.1021/acschembio.2c00290.
|
Crystal structure of pepper RNA aptamer in complex with
hbc ligand and fab bl3-6 . SNAP output
|
|
7t1n
|
transcription |
multiple methods: solution nmr, solution
scattering |
Pham VV, Gao M, Meagher JL, Smith JL, D'Souza VM |
(2022) "A
structure-based mechanism for displacement of the HEXIM
adapter from 7SK small nuclear RNA." Commun
Biol, 5, 819. doi: 10.1038/s42003-022-03734-w.
|
Solution structure of 7sk stem-loop 1 with hexim
arginine rich motif . SNAP output
|
|
7t1o
|
transcription |
multiple methods: solution nmr, solution
scattering |
Pham VV, Gao M, Meagher JL, Smith JL, D'Souza VM |
(2022) "A
structure-based mechanism for displacement of the HEXIM
adapter from 7SK small nuclear RNA." Commun
Biol, 5, 819. doi: 10.1038/s42003-022-03734-w.
|
Solution structure of 7sk stem-loop 1 with hiv-1 tat
subtype g arginine rich motif . SNAP output
|
|
7t1p
|
transcription |
multiple methods: solution nmr, solution
scattering |
Pham VV, Gao M, Meagher JL, Smith JL, D'Souza VM |
(2022) "A
structure-based mechanism for displacement of the HEXIM
adapter from 7SK small nuclear RNA." Commun
Biol, 5, 819. doi: 10.1038/s42003-022-03734-w.
|
Solution structure of 7sk stem-loop 1 with hiv-1 tat
finland arginine rich motif . SNAP output
|
|
7t3j
|
hydrolase-RNA |
cryo-EM (3.2 Å) |
Mukherjee IA, Gabel C, Noinaj N, Bondy-Denomy J,
Chang L |
(2022) "Structural
basis of AcrIF24 as an anti-CRISPR protein and
transcriptional suppressor."
Nat.Chem.Biol., 18,
1417-1424. doi: 10.1038/s41589-022-01137-w.
|
cryo-EM structure of csy-acrif24 . SNAP output
|
|
7t3k
|
hydrolase-RNA |
cryo-EM (3.5 Å) |
Mukherjee IA, Gabel C, Noinaj N, Bondy-Denomy J,
Chang L |
(2022) "Structural
basis of AcrIF24 as an anti-CRISPR protein and
transcriptional suppressor."
Nat.Chem.Biol., 18,
1417-1424. doi: 10.1038/s41589-022-01137-w.
|
cryo-EM structure of csy-acrif24 dimer . SNAP output
|
|
7tj2
|
viral protein-RNA |
cryo-EM (3.2 Å) |
Frazier MN, Wilson IM, Krahn JM, Butay KJ, Dillard
LB, Borgnia MJ, Stanley RE |
(2022) "Flipped
over U: structural basis for dsRNA cleavage by the
SARS-CoV-2 endoribonuclease." Nucleic Acids
Res., 50, 8290-8301. doi:
10.1093/nar/gkac589.
|
Sars-cov-2 endoribonuclease nsp15 bound to dsrna .
SNAP output
|
|
7tm3
|
ribosome |
cryo-EM (3.25 Å) |
Smalinskaite L, Kim MK, Lewis AJO, Keenan RJ, Hegde
RS |
(2022) "Mechanism
of an intramembrane chaperone for multipass membrane
proteins." Nature, 611,
161-166. doi: 10.1038/s41586-022-05336-2.
|
Structure of the rabbit 80s ribosome stalled on a 2-tmd
rhodopsin intermediate in complex with the multipass
translocon . SNAP
output
|
|
7tnx
|
immune system-RNA |
cryo-EM (3.54 Å) |
Wang W, Pyle AM |
(2022) "The
RIG-I receptor adopts two different conformations for
distinguishing host from viral RNA ligands."
Mol.Cell, 82, 4131-4144.e6.
doi: 10.1016/j.molcel.2022.09.029.
|
cryo-EM structure of rig-i in complex with p3dsrna .
SNAP output
|
|
7tny
|
immune system-RNA |
cryo-EM (3.2 Å) |
Wang W, Pyle AM |
(2022) "The
RIG-I receptor adopts two different conformations for
distinguishing host from viral RNA ligands."
Mol.Cell, 82, 4131. doi:
10.1016/j.molcel.2022.09.029.
|
cryo-EM structure of rig-i in complex with p2dsrna .
SNAP output
|
|
7tnz
|
immune system-RNA |
cryo-EM (3.54 Å) |
Wang W, Pyle AM |
(2022) "The
RIG-I receptor adopts two different conformations for
distinguishing host from viral RNA ligands."
Mol.Cell, 82, 4131. doi:
10.1016/j.molcel.2022.09.029.
|
cryo-EM structure of rig-i in complex with p1dsrna .
SNAP output
|
|
7to0
|
immune system-RNA |
cryo-EM (3.5 Å) |
Wang W, Pyle AM |
(2022) "The
RIG-I receptor adopts two different conformations for
distinguishing host from viral RNA ligands."
Mol.Cell, 82, 4131. doi:
10.1016/j.molcel.2022.09.029.
|
cryo-EM structure of rig-i in complex with ohdsrna .
SNAP output
|
|
7to1
|
immune system-RNA |
cryo-EM (3.66 Å) |
Wang W, Pyle AM |
(2022) "The
RIG-I receptor adopts two different conformations for
distinguishing host from viral RNA ligands."
Mol.Cell, 82, 4131. doi:
10.1016/j.molcel.2022.09.029.
|
cryo-EM structure of rig-i bound to the end of p3slr30
(+atp) . SNAP output
|
|
7to2
|
immune system-RNA |
cryo-EM (3.2 Å) |
Wang W, Pyle AM |
(2022) "The
RIG-I receptor adopts two different conformations for
distinguishing host from viral RNA ligands."
Mol.Cell, 82, 4131. doi:
10.1016/j.molcel.2022.09.029.
|
cryo-EM structure of rig-i bound to the internal sites
of p3slr30 (+atp) . SNAP
output
|
|
7too
|
ribosome |
cryo-EM (2.7 Å) |
Loveland AB, Svidritskiy E, Susorov D, Lee S, Park A,
Zvornicanin S, Demo G, Gao FB, Korostelev AA |
(2022) "Ribosome
inhibition by C9ORF72-ALS/FTD-associated poly-PR and
poly-GR proteins revealed by cryo-EM." Nat
Commun, 13, 2776. doi: 10.1038/s41467-022-30418-0.
|
Yeast 80s ribosome bound with the als-ftd-associated
dipeptide repeat protein gr20 . SNAP output
|
|
7top
|
ribosome |
cryo-EM (2.4 Å) |
Loveland AB, Svidritskiy E, Susorov D, Lee S, Park A,
Zvornicanin S, Demo G, Gao FB, Korostelev AA |
(2022) "Ribosome
inhibition by C9ORF72-ALS/FTD-associated poly-PR and
poly-GR proteins revealed by cryo-EM." Nat
Commun, 13, 2776. doi: 10.1038/s41467-022-30418-0.
|
Yeast 80s ribosome bound with the als-ftd-associated
dipeptide repeat protein pr20 . SNAP output
|
|
7toq
|
ribosome |
cryo-EM (3.1 Å) |
Loveland AB, Svidritskiy E, Susorov D, Lee S, Park A,
Zvornicanin S, Demo G, Gao FB, Korostelev AA |
(2022) "Ribosome
inhibition by C9ORF72-ALS/FTD-associated poly-PR and
poly-GR proteins revealed by cryo-EM." Nat
Commun, 13, 2776. doi: 10.1038/s41467-022-30418-0.
|
Mammalian 80s ribosome bound with the
als-ftd-associated dipeptide repeat protein poly-pr .
SNAP output
|
|
7tor
|
ribosome |
cryo-EM (2.9 Å) |
Loveland AB, Svidritskiy E, Susorov D, Lee S, Park A,
Zvornicanin S, Demo G, Gao FB, Korostelev AA |
(2022) "Ribosome
inhibition by C9ORF72-ALS/FTD-associated poly-PR and
poly-GR proteins revealed by cryo-EM." Nat
Commun, 13, 2776. doi: 10.1038/s41467-022-30418-0.
|
Mammalian 80s ribosome bound with the
als-ftd-associated dipeptide repeat protein gr20 .
SNAP output
|
|
7tos
|
ribosome |
cryo-EM (2.9 Å) |
Loveland AB, Svidritskiy E, Susorov D, Lee S, Park A,
Zvornicanin S, Demo G, Gao FB, Korostelev AA |
(2022) "Ribosome
inhibition by C9ORF72-ALS/FTD-associated poly-PR and
poly-GR proteins revealed by cryo-EM." Nat
Commun, 13, 2776. doi: 10.1038/s41467-022-30418-0.
|
E. coli 70s ribosomes bound with the als-ftd-associated
dipeptide repeat protein pr20 . SNAP output
|
|
7tql
|
ribosome |
cryo-EM (3.2 Å) |
Lapointe CP, Grosely R, Sokabe M, Alvarado C, Wang J,
Montabana E, Villa N, Shin BS, Dever TE, Fraser CS,
Fernandez IS, Puglisi JD |
(2022) "eIF5B
and eIF1A reorient initiator tRNA to allow ribosomal
subunit joining." Nature,
607, 185-190. doi: 10.1038/s41586-022-04858-z.
|
Cryoem structure of the human 40s small ribosomal
subunit in complex with translation initiation factors
eif1a and eif5b. . SNAP
output
|
|
7tqv
|
viral protein-RNA |
cryo-EM (3.43 Å) |
Frazier MN, Wilson IM, Krahn JM, Butay KJ, Dillard
LB, Borgnia MJ, Stanley RE |
(2022) "Flipped
over U: structural basis for dsRNA cleavage by the
SARS-CoV-2 endoribonuclease." Nucleic Acids
Res., 50, 8290-8301. doi:
10.1093/nar/gkac589.
|
Sars-cov-2 endoribonuclease nsp15 bound to dsrna .
SNAP output
|
|
7tr6
|
RNA binding protein |
cryo-EM (3.4 Å) |
Hu C, Ni D, Nam KH, Majumdar S, McLean J, Stahlberg
H, Terns MP, Ke A |
(2022) "Allosteric
control of type I-A CRISPR-Cas3 complexes and
establishment as effective nucleic acid detection and
human genome editing tools." Mol.Cell,
82, 2754-2768.e5. doi: 10.1016/j.molcel.2022.06.007.
|
Cascade complex from type i-a crispr-cas system .
SNAP output
|
|
7tr8
|
RNA binding protein |
cryo-EM (3.6 Å) |
Hu C, Ni D, Nam KH, Majumdar S, McLean J, Stahlberg
H, Terns MP, Ke A |
(2022) "Allosteric
control of type I-A CRISPR-Cas3 complexes and
establishment as effective nucleic acid detection and
human genome editing tools." Mol.Cell,
82, 2754-2768.e5. doi: 10.1016/j.molcel.2022.06.007.
|
Cascade complex from type i-a crispr-cas system .
SNAP output
|
|
7trc
|
replication |
cryo-EM (3.3 Å) |
Liu B, He Y, Wang Y, Song H, Zhou ZH, Feigon J |
(2022) "Structure
of active human telomerase with telomere shelterin
protein TPP1." Nature,
604, 578-583. doi: 10.1038/s41586-022-04582-8.
|
Human telomerase h-aca rnp at 3.3 angstrom . SNAP output
|
|
7ttu
|
ribosome |
cryo-EM (3.0 Å) |
Perlaza-Jimenez L, Tan KS, Piper SJ, Johnson RM,
Bamert RS, Stubenrauch CJ, Wright A, Lupton D, Lithgow T,
Belousoff MJ |
(2022) "A
Structurally Characterized Staphylococcus aureus
Evolutionary Escape Route from Treatment with the
Antibiotic Linezolid." Microbiol Spectr,
10, e0058322. doi: 10.1128/spectrum.00583-22.
|
50s ribosomal subunit from staphylococcus aureus
(strain atcc43300) . SNAP output
|
|
7ttw
|
ribosome |
cryo-EM (2.9 Å) |
Perlaza-Jimenez L, Tan KS, Piper SJ, Johnson RM,
Bamert RS, Stubenrauch CJ, Wright A, Lupton D, Lithgow T,
Belousoff MJ |
(2022) "A
Structurally Characterized Staphylococcus aureus
Evolutionary Escape Route from Treatment with the
Antibiotic Linezolid." Microbiol Spectr,
10, e0058322. doi: 10.1128/spectrum.00583-22.
|
50s ribosomal subunit from staphylococcus aureus
containing double mutation in ul3 imparting linezolid
resistance . SNAP
output
|
|
7tut
|
ribosome |
cryo-EM (3.88 Å) |
Smalinskaite L, Kim MK, Lewis AJO, Keenan RJ, Hegde
RS |
(2022) "Mechanism
of an intramembrane chaperone for multipass membrane
proteins." Nature, 611,
161-166. doi: 10.1038/s41586-022-05336-2.
|
Structure of the rabbit 80s ribosome stalled on a 4-tmd
rhodopsin intermediate in complex with the multipass
translocon . SNAP
output
|
|
7tuv
|
hydrolase-RNA |
X-ray (2.225 Å) |
Cesaro G, da Soler HT, Guerra-Slompo EP, Haouz A,
Legrand P, Zanchin NIT, Guimaraes BG |
(2023) "Trypanosoma
brucei RRP44: a versatile enzyme for processing
structured and non-structured RNA substrates."
Nucleic Acids Res., 51,
380-395. doi: 10.1093/nar/gkac1199.
|
Crystal structure of the exoribonucleolytic module of
t. brucei rrp44 . SNAP
output
|
|
7u0h
|
ribosome |
cryo-EM (2.76 Å) |
Cruz VE, Sekulski K, Peddada N, Sailer C,
Balasubramanian S, Weirich CS, Stengel F, Erzberger
JP |
(2022) "Sequence-specific
remodeling of a topologically complex RNP substrate by
Spb4." Nat.Struct.Mol.Biol.,
29, 1228-1238. doi: 10.1038/s41594-022-00874-9.
|
State ne1 nucleolar 60s ribosome biogenesis
intermediate - overall model . SNAP output
|
|
7u0y
|
immune system-RNA |
X-ray (2.66 Å) |
Rees HC, Gogacz W, Li NS, Koirala D, Piccirilli
JA |
(2022) "Structural
Basis for Fluorescence Activation by Pepper RNA."
Acs Chem.Biol., 17,
1866-1875. doi: 10.1021/acschembio.2c00290.
|
Crystal structure of pepper RNA aptamer in complex with
hbc599 ligand and fab bl3-6 . SNAP output
|
|
7u2a
|
ligase-RNA |
cryo-EM (4.1 Å) |
Kuhle B, Hirschi M, Doerfel LK, Lander GC, Schimmel
P |
(2022) "Structural
basis for shape-selective recognition and
aminoacylation of a D-armless human mitochondrial
tRNA." Nat Commun, 13,
5100. doi: 10.1038/s41467-022-32544-1.
|
Cryo-electron microscopy structure of human mt-serrs in
complex with mt-trna (gcu) . SNAP output
|
|
7u2b
|
ligase-RNA |
cryo-EM (4.1 Å) |
Kuhle B, Hirschi M, Doerfel LK, Lander GC, Schimmel
P |
(2022) "Structural
basis for shape-selective recognition and
aminoacylation of a D-armless human mitochondrial
tRNA." Nat Commun, 13,
5100. doi: 10.1038/s41467-022-32544-1.
|
Cryo-electron microscopy structure of human mt-serrs in
complex with mt-trna(gcu-tl) . SNAP output
|
|
7u2h
|
ribosome |
X-ray (2.55 Å) |
Syroegin EA, Aleksandrova EV, Polikanov YS |
(2022) "Structural
basis for the inability of chloramphenicol to inhibit
peptide bond formation in the presence of A-site
glycine." Nucleic Acids Res.,
50, 7669-7679. doi: 10.1093/nar/gkac548.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with mrna, aminoacylated a-site
gly-nh-trnagly, aminoacylated p-site fmet-nh-trnamet,
and deacylated e-site trnagly at 2.55a resolution .
SNAP output
|
|
7u2i
|
ribosome |
X-ray (2.55 Å) |
Syroegin EA, Aleksandrova EV, Polikanov YS |
(2022) "Structural
basis for the inability of chloramphenicol to inhibit
peptide bond formation in the presence of A-site
glycine." Nucleic Acids Res.,
50, 7669-7679. doi: 10.1093/nar/gkac548.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with mrna, aminoacylated a-site
gly-nh-trnagly, aminoacylated p-site fmet-nh-trnamet,
deacylated e-site trnagly, and chloramphenicol at 2.55a
resolution . SNAP
output
|
|
7u2j
|
ribosome |
X-ray (2.55 Å) |
Syroegin EA, Aleksandrova EV, Polikanov YS |
(2022) "Structural
basis for the inability of chloramphenicol to inhibit
peptide bond formation in the presence of A-site
glycine." Nucleic Acids Res.,
50, 7669-7679. doi: 10.1093/nar/gkac548.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with mrna, aminoacylated a-site
gly-nh-trnagly, peptidyl p-site fmac-nh-trnamet,
deacylated e-site trnagly, and chloramphenicol at 2.55a
resolution . SNAP
output
|
|
7ucj
|
ribosome-inhibitor |
cryo-EM (3.1 Å) |
Arango D, Sturgill D, Yang R, Kanai T, Bauer P, Roy
J, Wang Z, Hosogane M, Schiffers S, Oberdoerffer S |
(2022) "Direct
epitranscriptomic regulation of mammalian translation
initiation through N4-acetylcytidine."
Mol.Cell, 82, 2797-2814.e11.
doi: 10.1016/j.molcel.2022.05.016.
|
Mammalian 80s translation initiation complex with mrna
and harringtonine . SNAP
output
|
|
7uck
|
ribosome-inhibitor |
cryo-EM (2.8 Å) |
Arango D, Sturgill D, Yang R, Kanai T, Bauer P, Roy
J, Wang Z, Hosogane M, Schiffers S, Oberdoerffer S |
(2022) "Direct
epitranscriptomic regulation of mammalian translation
initiation through N4-acetylcytidine."
Mol.Cell, 82, 2797-2814.e11.
doi: 10.1016/j.molcel.2022.05.016.
|
80s translation initiation complex with ac4c(-1) mrna
and harringtonine . SNAP
output
|
|
7ug6
|
ribosome |
cryo-EM (2.9 Å) |
Yelland JN, Bravo JPK, Black JJ, Taylor DW, Johnson
AW |
(2023) "A single
2'-O-methylation of ribosomal RNA gates assembly of a
functional ribosome."
Nat.Struct.Mol.Biol., 30,
91-98. doi: 10.1038/s41594-022-00891-8.
|
cryo-EM structure of pre-60s ribosomal subunit,
unmethylated g2922 . SNAP output
|
|
7ug7
|
ribosome |
cryo-EM (2.58 Å) |
Wieland M, Holm M, Rundlet EJ, Morici M, Koller TO,
Maviza TP, Pogorevc D, Osterman IA, Muller R, Blanchard
SC, Wilson DN |
(2022) "The
cyclic octapeptide antibiotic argyrin B inhibits
translation by trapping EF-G on the ribosome during
translocation." Proc.Natl.Acad.Sci.USA,
119, e2114214119. doi: 10.1073/pnas.2114214119.
|
70s ribosome complex in an intermediate state of
translocation bound to ef-g(gdp) stalled by argyrin b .
SNAP output
|
|
7uim
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Chung K, Xu L, Chai P, Peng J, Devarkar SC, Pyle
AM |
(2022) "Structures
of a mobile intron retroelement poised to attack its
structured DNA target." Science,
378, 627-634. doi: 10.1126/science.abq2844.
|
Cryoem structure of an group ii intron retroelement
(apo-complex) . SNAP
output
|
|
7uj1
|
RNA binding protein-RNA |
X-ray (3.5 Å) |
Wang J, Sachpatzidis A, Christian TD, Lomakin IB,
Garen A, Konigsberg WH |
(2022) "Insight
into the Tumor Suppression Mechanism from the Structure
of Human Polypyrimidine Splicing Factor (PSF/SFPQ)
Complexed with a 30mer RNA from Murine Virus-like 30S
Transcript-1." Biochemistry,
61, 1723-1734. doi: 10.1021/acs.biochem.2c00192.
|
Crystal structure of psf-RNA complex . SNAP output
|
|
7umk
|
virus |
cryo-EM (4.1 Å) |
Jenni S, Horwitz JA, Bloyet LM, Whelan SPJ, Harrison
SC |
(2022) "Visualizing
molecular interactions that determine assembly of a
bullet-shaped vesicular stomatitis virus particle."
Nat Commun, 13, 4802. doi:
10.1038/s41467-022-32223-1.
|
Structure of vesicular stomatitis virus (helical
reconstruction, 4.1 Å resolution) . SNAP output
|
|
7uml
|
viral protein-RNA |
cryo-EM (3.5 Å) |
Jenni S, Horwitz JA, Bloyet LM, Whelan SPJ, Harrison
SC |
(2022) "Visualizing
molecular interactions that determine assembly of a
bullet-shaped vesicular stomatitis virus particle."
Nat Commun, 13, 4802. doi:
10.1038/s41467-022-32223-1.
|
Structure of vesicular stomatitis virus (local
reconstruction, 3.5 Å resolution) . SNAP output
|
|
7unr
|
ribosome |
cryo-EM (2.9 Å) |
Basu RS, Sherman MB, Gagnon MG |
(2022) "Compact IF2 allows initiator tRNA accommodation
into the P site and gates the ribosome to elongation."
Nat Commun, 13, 3388. doi:
10.1038/s41467-022-31129-2.
|
Pseudomonas aeruginosa 70s ribosome initiation complex
bound to compact if2-gdp (composite structure i-a) .
SNAP output
|
|
7unu
|
ribosome |
cryo-EM (2.9 Å) |
Basu RS, Sherman MB, Gagnon MG |
(2022) "Compact IF2 allows initiator tRNA accommodation
into the P site and gates the ribosome to elongation."
Nat Commun, 13, 3388. doi:
10.1038/s41467-022-31129-2.
|
Pseudomonas aeruginosa 70s ribosome initiation complex
bound to compact if2-gdp (composite structure i-b) .
SNAP output
|
|
7unv
|
ribosome |
cryo-EM (2.7 Å) |
Basu RS, Sherman MB, Gagnon MG |
(2022) "Compact IF2 allows initiator tRNA accommodation
into the P site and gates the ribosome to elongation."
Nat Commun, 13, 3388. doi:
10.1038/s41467-022-31129-2.
|
Pseudomonas aeruginosa 70s ribosome initiation complex
bound to if2-gdpcp (structure ii-a) . SNAP output
|
|
7unw
|
ribosome |
cryo-EM (2.6 Å) |
Basu RS, Sherman MB, Gagnon MG |
(2022) "Compact IF2 allows initiator tRNA accommodation
into the P site and gates the ribosome to elongation."
Nat Commun, 13, 3388. doi:
10.1038/s41467-022-31129-2.
|
Pseudomonas aeruginosa 70s ribosome initiation complex
bound to if2-gdpcp (structure ii-b) . SNAP output
|
|
7uo0
|
hydrolase-RNA |
cryo-EM (3.4 Å) |
Zhu J, Huang W, Zhao J, Huynh L, Taylor DJ, Harris
ME |
(2022) "Structural
and mechanistic basis for recognition of alternative
tRNA precursor substrates by bacterial ribonuclease
P." Nat Commun, 13, 5120.
doi: 10.1038/s41467-022-32843-7.
|
E.coli rnasep holoenzyme with mg2+ . SNAP output
|
|
7uo1
|
hydrolase-RNA |
cryo-EM (3.2 Å) |
Zhu J, Huang W, Zhao J, Huynh L, Taylor DJ, Harris
ME |
(2022) "Structural
and mechanistic basis for recognition of alternative
tRNA precursor substrates by bacterial ribonuclease
P." Nat Commun, 13, 5120.
doi: 10.1038/s41467-022-32843-7.
|
E.coli rnasep holoenzyme with mg2+ . SNAP output
|
|
7uo2
|
hydrolase-RNA |
cryo-EM (3.1 Å) |
Zhu J, Huang W, Zhao J, Huynh L, Taylor DJ, Harris
ME |
(2022) "Structural
and mechanistic basis for recognition of alternative
tRNA precursor substrates by bacterial ribonuclease
P." Nat Commun, 13, 5120.
doi: 10.1038/s41467-022-32843-7.
|
E.coli rnasep holoenzyme with mg2+ . SNAP output
|
|
7uo4
|
replication |
cryo-EM (3.38 Å) |
Malone BF, Perry JK, Olinares PDB, Lee HW, Chen J,
Appleby TC, Feng JY, Bilello JP, Ng H, Sotiris J, Ebrahim
M, Chua EYD, Mendez JH, Eng ET, Landick R, Gotte M, Chait
BT, Campbell EA, Darst SA |
(2023) "Structural
basis for substrate selection by the SARS-CoV-2
replicase." Nature, 614,
781-787. doi: 10.1038/s41586-022-05664-3.
|
Sars-cov-2 replication-transcription complex bound to
remdesivir triphosphate, in a pre-catalytic state .
SNAP output
|
|
7uo5
|
hydrolase-RNA |
cryo-EM (3.1 Å) |
Zhu J, Huang W, Zhao J, Huynh L, Taylor DJ, Harris
ME |
(2022) "Structural
and mechanistic basis for recognition of alternative
tRNA precursor substrates by bacterial ribonuclease
P." Nat Commun, 13, 5120.
doi: 10.1038/s41467-022-32843-7.
|
E.coli rnasep holoenzyme with mg2+ . SNAP output
|
|
7uo7
|
replication |
cryo-EM (3.09 Å) |
Malone BF, Perry JK, Olinares PDB, Lee HW, Chen J,
Appleby TC, Feng JY, Bilello JP, Ng H, Sotiris J, Ebrahim
M, Chua EYD, Mendez JH, Eng ET, Landick R, Gotte M, Chait
BT, Campbell EA, Darst SA |
(2023) "Structural
basis for substrate selection by the SARS-CoV-2
replicase." Nature, 614,
781-787. doi: 10.1038/s41586-022-05664-3.
|
Sars-cov-2 replication-transcription complex bound to
atp, in a pre-catalytic state . SNAP output
|
|
7uo9
|
replication |
cryo-EM (3.13 Å) |
Malone BF, Perry JK, Olinares PDB, Lee HW, Chen J,
Appleby TC, Feng JY, Bilello JP, Ng H, Sotiris J, Ebrahim
M, Chua EYD, Mendez JH, Eng ET, Landick R, Gotte M, Chait
BT, Campbell EA, Darst SA |
(2023) "Structural
basis for substrate selection by the SARS-CoV-2
replicase." Nature, 614,
781-787. doi: 10.1038/s41586-022-05664-3.
|
Sars-cov-2 replication-transcription complex bound to
utp, in a pre-catalytic state . SNAP output
|
|
7uob
|
replication |
cryo-EM (2.68 Å) |
Malone BF, Perry JK, Olinares PDB, Lee HW, Chen J,
Appleby TC, Feng JY, Bilello JP, Ng H, Sotiris J, Ebrahim
M, Chua EYD, Mendez JH, Eng ET, Landick R, Gotte M, Chait
BT, Campbell EA, Darst SA |
(2023) "Structural
basis for substrate selection by the SARS-CoV-2
replicase." Nature, 614,
781-787. doi: 10.1038/s41586-022-05664-3.
|
Sars-cov-2 replication-transcription complex bound to
gtp, in a pre-catalytic state . SNAP output
|
|
7uoe
|
replication |
cryo-EM (2.67 Å) |
Malone BF, Perry JK, Olinares PDB, Lee HW, Chen J,
Appleby TC, Feng JY, Bilello JP, Ng H, Sotiris J, Ebrahim
M, Chua EYD, Mendez JH, Eng ET, Landick R, Gotte M, Chait
BT, Campbell EA, Darst SA |
(2023) "Structural
basis for substrate selection by the SARS-CoV-2
replicase." Nature, 614,
781-787. doi: 10.1038/s41586-022-05664-3.
|
Sars-cov-2 replication-transcription complex bound to
ctp, in a pre-catalytic state . SNAP output
|
|
7uoo
|
ribosome |
cryo-EM (2.34 Å) |
Sekulski K, Cruz VE, Weirich CS, Erzberger JP |
(2023) "rRNA
methylation by Spb1 regulates the GTPase activity of
Nog2 during 60S ribosomal subunit assembly."
Nat Commun, 14, 1207. doi:
10.1038/s41467-023-36867-5.
|
Nucleoplasmic pre-60s intermediate of the nog2
containing pre-rotation state . SNAP output
|
|
7uph
|
ribosome |
cryo-EM (4.18 Å) |
Kim DS, Watkins A, Bidstrup E, Lee J, Topkar V,
Kofman C, Schwarz KJ, Liu Y, Pintilie G, Roney E, Das R,
Jewett MC |
(2022) "Three-dimensional
structure-guided evolution of a ribosome with tethered
subunits." Nat.Chem.Biol.,
18, 990-998. doi: 10.1038/s41589-022-01064-w.
|
Structure of a ribosome with tethered subunits .
SNAP output
|
|
7uqb
|
ribosome |
cryo-EM (2.43 Å) |
Sekulski K, Cruz VE, Weirich CS, Erzberger JP |
(2023) "rRNA
methylation by Spb1 regulates the GTPase activity of
Nog2 during 60S ribosomal subunit assembly."
Nat Commun, 14, 1207. doi:
10.1038/s41467-023-36867-5.
|
Nucleoplasmic pre-60s intermediate of the nog2
containing pre-rotation state from a spb1-d52a strain
with alf4 . SNAP
output
|
|
7uqz
|
ribosome |
cryo-EM (2.44 Å) |
Sekulski K, Cruz VE, Weirich CS, Erzberger JP |
(2023) "rRNA
methylation by Spb1 regulates the GTPase activity of
Nog2 during 60S ribosomal subunit assembly."
Nat Commun, 14, 1207. doi:
10.1038/s41467-023-36867-5.
|
Nucleoplasmic pre-60s intermediate of the nog2
containing pre-rotation state from a spb1 d52a strain .
SNAP output
|
|
7uu3
|
hydrolase-RNA |
X-ray (3.099 Å) |
Yang H, Kim K, Li S, Pacheco J, Chen XS |
(2022) "Structural
basis of sequence-specific RNA recognition by the
antiviral factor APOBEC3G." Nat Commun,
13, 7498. doi: 10.1038/s41467-022-35201-9.
|
Crystal structure of apobec3g complex with 3'overhangs
RNA-complex . SNAP
output
|
|
7uu4
|
hydrolase-RNA |
X-ray (2.1 Å) |
Yang H, Kim K, Li S, Pacheco J, Chen XS |
(2022) "Structural
basis of sequence-specific RNA recognition by the
antiviral factor APOBEC3G." Nat Commun,
13, 7498. doi: 10.1038/s41467-022-35201-9.
|
Crystal structure of apobec3g complex with ssrna .
SNAP output
|
|
7uu5
|
hydrolase-RNA |
X-ray (2.9 Å) |
Yang H, Kim K, Li S, Pacheco J, Chen XS |
(2022) "Structural
basis of sequence-specific RNA recognition by the
antiviral factor APOBEC3G." Nat Commun,
13, 7498. doi: 10.1038/s41467-022-35201-9.
|
Crystal structure of apobec3g complex with 5'-overhang
dsrna . SNAP output
|
|
7uvv
|
ribosome-RNA |
cryo-EM (2.5 Å) |
Morgan CE, Kang YS, Green AB, Smith KP, Dowgiallo MG,
Miller BC, Chiaraviglio L, Truelson KA, Zulauf KE,
Rodriguez S, Kang AD, Manetsch R, Yu EW, Kirby JE |
(2023) "Streptothricin
F is a bactericidal antibiotic effective against highly
drug-resistant gram-negative bacteria that interacts
with the 30S subunit of the 70S ribosome." Plos
Biol., 21, e3002091. doi:
10.1371/journal.pbio.3002091.
|
A. baumannii ribosome-streptothricin-f complex: 70s
with p-site trna . SNAP
output
|
|
7uvw
|
ribosome-RNA |
cryo-EM (2.37 Å) |
Morgan CE, Kang YS, Green AB, Smith KP, Dowgiallo MG,
Miller BC, Chiaraviglio L, Truelson KA, Zulauf KE,
Rodriguez S, Kang AD, Manetsch R, Yu EW, Kirby JE |
(2023) "Streptothricin
F is a bactericidal antibiotic effective against highly
drug-resistant gram-negative bacteria that interacts
with the 30S subunit of the 70S ribosome." Plos
Biol., 21, e3002091. doi:
10.1371/journal.pbio.3002091.
|
A. baumannii ribosome: 70s with e-site trna . SNAP output
|
|
7uvx
|
ribosome-RNA |
cryo-EM (2.35 Å) |
Morgan CE, Kang YS, Green AB, Smith KP, Dowgiallo MG,
Miller BC, Chiaraviglio L, Truelson KA, Zulauf KE,
Rodriguez S, Kang AD, Manetsch R, Yu EW, Kirby JE |
(2023) "Streptothricin
F is a bactericidal antibiotic effective against highly
drug-resistant gram-negative bacteria that interacts
with the 30S subunit of the 70S ribosome." Plos
Biol., 21, e3002091. doi:
10.1371/journal.pbio.3002091.
|
A. baumannii 70s ribosome-streptothricin-f complex .
SNAP output
|
|
7uvy
|
ribosome-RNA |
cryo-EM (2.39 Å) |
Morgan CE, Kang YS, Green AB, Smith KP, Dowgiallo MG,
Miller BC, Chiaraviglio L, Truelson KA, Zulauf KE,
Rodriguez S, Kang AD, Manetsch R, Yu EW, Kirby JE |
(2023) "Streptothricin
F is a bactericidal antibiotic effective against highly
drug-resistant gram-negative bacteria that interacts
with the 30S subunit of the 70S ribosome." Plos
Biol., 21, e3002091. doi:
10.1371/journal.pbio.3002091.
|
A. baumannii ribosome-streptothricin-d complex: 70s
with p-site trna . SNAP
output
|
|
7uvz
|
ribosome-RNA |
cryo-EM (2.21 Å) |
Morgan CE, Kang YS, Green AB, Smith KP, Dowgiallo MG,
Miller BC, Chiaraviglio L, Truelson KA, Zulauf KE,
Rodriguez S, Kang AD, Manetsch R, Yu EW, Kirby JE |
(2023) "Streptothricin
F is a bactericidal antibiotic effective against highly
drug-resistant gram-negative bacteria that interacts
with the 30S subunit of the 70S ribosome." Plos
Biol., 21, e3002091. doi:
10.1371/journal.pbio.3002091.
|
A. baumannii ribosome-streptothricin-d complex: 70s
with e-site trna . SNAP
output
|
|
7uw1
|
ribosome-RNA |
cryo-EM (2.21 Å) |
Morgan CE, Kang YS, Green AB, Smith KP, Dowgiallo MG,
Miller BC, Chiaraviglio L, Truelson KA, Zulauf KE,
Rodriguez S, Kang AD, Manetsch R, Yu EW, Kirby JE |
(2023) "Streptothricin
F is a bactericidal antibiotic effective against highly
drug-resistant gram-negative bacteria that interacts
with the 30S subunit of the 70S ribosome." Plos
Biol., 21, e3002091. doi:
10.1371/journal.pbio.3002091.
|
A. baumannii 70s ribosome-streptothricin-d complex .
SNAP output
|
|
7uws
|
viral protein-RNA |
cryo-EM (3.47 Å) |
Zhou K, Si Z, Ge P, Tsao J, Luo M, Zhou ZH |
(2022) "Atomic
model of vesicular stomatitis virus and mechanism of
assembly." Nat Commun,
13, 5980. doi: 10.1038/s41467-022-33664-4.
|
Atomic model of the partial vsv nucleocapsid . SNAP output
|
|
7uxa
|
splicing-RNA |
cryo-EM (3.28 Å) |
Hayne CK, Butay KJU, Stewart ZD, Krahn JM, Perera L,
Williams JG, Petrovitch RM, Deterding LJ, Matera AG,
Borgnia MJ, Stanley RE |
(2023) "Structural
basis for pre-tRNA recognition and processing by the
human tRNA splicing endonuclease complex."
Nat.Struct.Mol.Biol., 30,
824-833. doi: 10.1038/s41594-023-00991-z.
|
Human trna splicing endonuclease complex bound to
pre-trna-arg . SNAP
output
|
|
7uzw
|
RNA binding protein-RNA |
cryo-EM (3.55 Å) |
Smith EM, Ferrell S, Tokars VL, Mondragon A |
(2022) "Structures
of an active type III-A CRISPR effector complex."
Structure, 30, 1109. doi:
10.1016/j.str.2022.05.013.
|
Staphylococcus epidermidis rp62a crispr effector
subcomplex . SNAP
output
|
|
7uzx
|
hydrolase-RNA |
cryo-EM (3.49 Å) |
Smith EM, Ferrell S, Tokars VL, Mondragon A |
(2022) "Structures
of an active type III-A CRISPR effector complex."
Structure, 30, 1109-1128.e6.
doi: 10.1016/j.str.2022.05.013.
|
Staphylococcus epidermidis rp62a crispr effector
subcomplex with non-self target RNA bound . SNAP output
|
|
7uzy
|
hydrolase-RNA |
cryo-EM (4.05 Å) |
Smith EM, Ferrell S, Tokars VL, Mondragon A |
(2022) "Structures
of an active type III-A CRISPR effector complex."
Structure, 30, 1109-1128.e6.
doi: 10.1016/j.str.2022.05.013.
|
Staphylococcus epidermidis rp62a crispr effector
complex with non-self target RNA 2 . SNAP output
|
|
7uzz
|
hydrolase-RNA |
cryo-EM (4.45 Å) |
Smith EM, Ferrell S, Tokars VL, Mondragon A |
(2022) "Structures
of an active type III-A CRISPR effector complex."
Structure, 30, 1109-1128.e6.
doi: 10.1016/j.str.2022.05.013.
|
Staphylococcus epidermidis rp62a crispr tall effector
complex . SNAP
output
|
|
7v00
|
hydrolase-RNA |
cryo-EM (3.87 Å) |
Smith EM, Ferrell S, Tokars VL, Mondragon A |
(2022) "Structures
of an active type III-A CRISPR effector complex."
Structure, 30, 1109-1128.e6.
doi: 10.1016/j.str.2022.05.013.
|
Staphylococcus epidermidis rp62a crispr tall effector
complex with bound atp . SNAP output
|
|
7v01
|
hydrolase-RNA |
cryo-EM (3.67 Å) |
Smith EM, Ferrell S, Tokars VL, Mondragon A |
(2022) "Structures
of an active type III-A CRISPR effector complex."
Structure, 30, 1109-1128.e6.
doi: 10.1016/j.str.2022.05.013.
|
Staphylococcus epidermidis rp62a crispr short effector
complex with self RNA target and atp . SNAP output
|
|
7v02
|
hydrolase-RNA |
cryo-EM (4.97 Å) |
Smith EM, Ferrell S, Tokars VL, Mondragon A |
(2022) "Structures
of an active type III-A CRISPR effector complex."
Structure, 30, 1109-1128.e6.
doi: 10.1016/j.str.2022.05.013.
|
Staphylococcus epidermidis rp62a crispr short effector
complex . SNAP
output
|
|
7v08
|
ribosome |
cryo-EM (2.36 Å) |
Sekulski K, Cruz VE, Weirich CS, Erzberger JP |
(2023) "rRNA
methylation by Spb1 regulates the GTPase activity of
Nog2 during 60S ribosomal subunit assembly."
Nat Commun, 14, 1207. doi:
10.1038/s41467-023-36867-5.
|
Nucleoplasmic pre-60s intermediate of the nog2
containing pre-rotation state from a spb1 d52a
suppressor 3 strain . SNAP output
|
|
7v2l
|
ribosome |
cryo-EM (3.3 Å) |
Singh J, Raina R, Vinothkumar KR, Anand R |
(2022) "Decoding
the Mechanism of Specific RNA Targeting by Ribosomal
Methyltransferases." Acs Chem.Biol.,
17, 829-839. doi: 10.1021/acschembio.1c00732.
|
T.thermophilus 30s ribosome with ksga, class k1k2 .
SNAP output
|
|
7v2m
|
ribosome |
cryo-EM (3.4 Å) |
Singh J, Raina R, Vinothkumar KR, Anand R |
(2022) "Decoding
the Mechanism of Specific RNA Targeting by Ribosomal
Methyltransferases." Acs Chem.Biol.,
17, 829-839. doi: 10.1021/acschembio.1c00732.
|
T.thermophilus 30s ribosome with ksga, class k1k4 .
SNAP output
|
|
7v2n
|
ribosome |
cryo-EM (3.6 Å) |
Singh J, Raina R, Vinothkumar KR, Anand R |
(2022) "Decoding
the Mechanism of Specific RNA Targeting by Ribosomal
Methyltransferases." Acs Chem.Biol.,
17, 829-839. doi: 10.1021/acschembio.1c00732.
|
T.thermophilus 30s ribosome with ksga, class k2 .
SNAP output
|
|
7v2o
|
ribosome |
cryo-EM (3.5 Å) |
Singh J, Raina R, Vinothkumar KR, Anand R |
(2022) "Decoding
the Mechanism of Specific RNA Targeting by Ribosomal
Methyltransferases." Acs Chem.Biol.,
17, 829-839. doi: 10.1021/acschembio.1c00732.
|
T.thermophilus 30s ribosome with ksga, class k4 .
SNAP output
|
|
7v2p
|
ribosome |
cryo-EM (3.3 Å) |
Singh J, Raina R, Vinothkumar KR, Anand R |
(2022) "Decoding
the Mechanism of Specific RNA Targeting by Ribosomal
Methyltransferases." Acs Chem.Biol.,
17, 829-839. doi: 10.1021/acschembio.1c00732.
|
T.thermophilus 30s ribosome with ksga, class k5 .
SNAP output
|
|
7v2q
|
ribosome |
cryo-EM (3.24 Å) |
Singh J, Raina R, Vinothkumar KR, Anand R |
(2022) "Decoding
the Mechanism of Specific RNA Targeting by Ribosomal
Methyltransferases." Acs Chem.Biol.,
17, 829-839. doi: 10.1021/acschembio.1c00732.
|
T.thermophilus 30s ribosome with ksga, class k6 .
SNAP output
|
|
7v2z
|
viral protein |
X-ray (2.1 Å) |
Lin M, Cui W, Tian H, Zhang Y, Chen C, Yang X, Chi H,
Mu Z, Chen C, Wang Z, Ji X, Yang H, Lin Z |
(2022) "Structural
Basis of Zika Virus Helicase in RNA Unwinding and ATP
Hydrolysis." Acs Infect Dis.,
8, 150-158. doi: 10.1021/acsinfecdis.1c00455.
|
Zikv ns3helicase in complex with ssrna and atp-mn2+ .
SNAP output
|
|
7v4g
|
oxidoreductase-RNA |
X-ray (2.1 Å) |
Kaur S, Tam NY, McDonough MA, Schofield CJ, Aik
WS |
(2022) "Mechanisms
of substrate recognition and N6-methyladenosine
demethylation revealed by crystal structures of
ALKBH5-RNA complexes." Nucleic Acids Res.,
50, 4148-4160. doi: 10.1093/nar/gkac195.
|
Crystal structure of human alkbh5 in complex with
m6a-containing ssrna . SNAP output
|
|
7v6c
|
RNA binding protein |
cryo-EM (3.3 Å) |
Yamaguchi S, Naganuma M, Nishizawa T, Kusakizako T,
Tomari Y, Nishimasu H, Nureki O |
(2022) "Structure
of the Dicer-2-R2D2 heterodimer bound to a small RNA
duplex." Nature, 607,
393-398. doi: 10.1038/s41586-022-04790-2.
|
Structure of the dicer-2-r2d2 heterodimer bound to
small RNA duplex . SNAP
output
|
|
7v93
|
RNA binding protein-RNA |
cryo-EM (3.0 Å) |
Kurihara N, Nakagawa R, Hirano H, Okazaki S, Tomita
A, Kobayashi K, Kusakizako T, Nishizawa T, Yamashita K,
Scott DA, Nishimasu H, Nureki O |
(2022) "Structure
of the type V-C CRISPR-Cas effector enzyme."
Mol.Cell, 82, 1865-1877.e4.
doi: 10.1016/j.molcel.2022.03.006.
|
cryo-EM structure of the cas12c2-sgrna binary complex .
SNAP output
|
|
7v9a
|
replication |
cryo-EM (3.94 Å) |
Wan F, Ding Y, Zhang Y, Wu Z, Li S, Yang L, Yan X,
Lan P, Li G, Wu J, Lei M |
(2021) "Zipper
head mechanism of telomere synthesis by human
telomerase." Cell Res.,
31, 1275-1290. doi: 10.1038/s41422-021-00586-7.
|
Biogenesis module of human telomerase holoenzyme .
SNAP output
|
|
7va3
|
hydrolase |
X-ray (1.8 Å) |
Zhang J, Zhang Q, Bartlam M |
"PaOrn Oligoribonuclease D11A mutant with substrate
pGpG complex structure." |
Paorn oligoribonuclease d11a mutant with substrate pgpg
complex structure . SNAP
output
|
|
7va6
|
hydrolase |
X-ray (2.1 Å) |
Zhang J, Zhang Q, Bartlam M |
"PaOrn Oligoribonuclease D11A mutant with RNA GU
complex structure." |
Paorn oligoribonuclease d11a mutant with RNA gu complex
structure . SNAP
output
|
|
7vg2
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Wang Q, Xue Y, Zhang L, Zhong Z, Feng S, Wang C, Xiao
L, Yang Z, Harris CJ, Wu Z, Zhai J, Yang M, Li S,
Jacobsen SE, Du J |
(2021) "Mechanism
of siRNA production by a plant Dicer-RNA complex in
dicing-competent conformation." Science,
374, 1152-1157. doi: 10.1126/science.abl4546.
|
cryo-EM structure of arabidopsis dcl3 in complex with a
40-bp RNA . SNAP
output
|
|
7vg3
|
RNA binding protein-RNA |
cryo-EM (3.73 Å) |
Wang Q, Xue Y, Zhang L, Zhong Z, Feng S, Wang C, Xiao
L, Yang Z, Harris CJ, Wu Z, Zhai J, Yang M, Li S,
Jacobsen SE, Du J |
(2021) "Mechanism
of siRNA production by a plant Dicer-RNA complex in
dicing-competent conformation." Science,
374, 1152-1157. doi: 10.1126/science.abl4546.
|
cryo-EM structure of arabidopsis dcl3 in complex with a
30-bp RNA . SNAP
output
|
|
7vki
|
RNA binding protein-RNA |
X-ray (1.65 Å) |
Liu D, Dredge BK, Bert AG, Pillman KA, Toubia J, Guo
W, Dyakov BJA, Migault MM, Conn VM, Conn SJ, Gregory PA,
Gingras AC, Patel D, Wu B, Goodall GJ |
(2023) "ESRP1
controls biogenesis and function of a large abundant
multiexon circRNA." Nucleic Acids Res.
doi: 10.1093/nar/gkad1138.
|
Esrp1 qrrm2 in complex with 12mer-RNA . SNAP output
|
|
7vkl
|
RNA binding protein-RNA |
X-ray (1.95 Å) |
Li X, Guo W, Wen Y, Meng C, Zhang Q, Chen H, Zhao X,
Wu B |
(2025) "Structural
basis for the RNA binding properties of mouse
IGF2BP3." Structure. doi: 10.1016/j.str.2025.01.022.
|
Crystal structure of mmimp3-kh12 in complex with
zipcode RNA . SNAP
output
|
|
7vpx
|
splicing |
cryo-EM (3.0 Å) |
Zhang X, Zhan X, Bian T, Yang F, Li P, Lu Y, Xing Z,
Fan R, Zhang QC, Shi Y |
(2024) "Structural
insights into branch site proofreading by human
spliceosome." Nat.Struct.Mol.Biol. doi:
10.1038/s41594-023-01188-0.
|
The cryo-EM structure of the human pre-a complex .
SNAP output
|
|
7vrl
|
RNA binding protein-RNA |
NMR |
Ye X, Yang W, Yi S, Zhao Y, Varani G, Jankowsky E,
Yang F |
(2023) "Two
distinct binding modes provide the RNA-binding protein
RbFox with extraordinary sequence specificity."
Nat Commun, 14, 701. doi:
10.1038/s41467-023-36394-3.
|
Solution structure of rbfox rrm bound to a non-cognate
RNA . SNAP output
|
|
7vsj
|
RNA binding protein-RNA |
X-ray (2.38 Å) |
Li X, Guo W, Wen Y, Meng C, Zhang Q, Chen H, Zhao X,
Wu B |
(2025) "Structural
basis for the RNA binding properties of mouse
IGF2BP3." Structure. doi: 10.1016/j.str.2025.01.022.
|
Crystal structure of mmimp3-rrm12 in complex with 9-mer
RNA . SNAP output
|
|
7vti
|
RNA binding protein-RNA |
X-ray (1.89 Å) |
Nakagawa R, Kannan S, Altae-Tran H, Takeda SN, Tomita
A, Hirano H, Kusakizako T, Nishizawa T, Yamashita K,
Zhang F, Nishimasu H, Nureki O |
(2022) "Structure
and engineering of the minimal type VI
CRISPR-Cas13bt3." Mol.Cell,
82, 3178-3192.e5. doi: 10.1016/j.molcel.2022.08.001.
|
Crystal structure of the cas13bt3-crrna binary complex
. SNAP output
|
|
7vtn
|
RNA binding protein-RNA |
cryo-EM (3.38 Å) |
Nakagawa R, Kannan S, Altae-Tran H, Takeda SN, Tomita
A, Hirano H, Kusakizako T, Nishizawa T, Yamashita K,
Zhang F, Nishimasu H, Nureki O |
(2022) "Structure
and engineering of the minimal type VI
CRISPR-Cas13bt3." Mol.Cell,
82, 3178-3192.e5. doi: 10.1016/j.molcel.2022.08.001.
|
cryo-EM structure of the cas13bt3-crrna-target RNA
ternary complex . SNAP
output
|
|
7w0a
|
RNA binding protein |
cryo-EM (3.12 Å) |
Su S, Wang J, Deng T, Yuan X, He J, Liu N, Li X,
Huang Y, Wang HW, Ma J |
(2022) "Structural
insights into dsRNA processing by Drosophila
Dicer-2-Loqs-PD." Nature,
607, 399-406. doi: 10.1038/s41586-022-04911-x.
|
Dmdicer2-loqspd-dsrna dimer status . SNAP output
|
|
7w0c
|
RNA binding protein |
cryo-EM (3.93 Å) |
Su S, Wang J, Deng T, Yuan X, He J, Liu N, Li X,
Huang Y, Wang HW, Ma J |
(2022) "Structural
insights into dsRNA processing by Drosophila
Dicer-2-Loqs-PD." Nature,
607, 399-406. doi: 10.1038/s41586-022-04911-x.
|
Dicer2-loqs-pd-dsrna complex at early-translocation
state . SNAP output
|
|
7w0d
|
RNA binding protein |
cryo-EM (4.18 Å) |
Su S, Wang J, Deng T, Yuan X, He J, Liu N, Li X,
Huang Y, Wang HW, Ma J |
(2022) "Structural
insights into dsRNA processing by Drosophila
Dicer-2-Loqs-PD." Nature,
607, 399-406. doi: 10.1038/s41586-022-04911-x.
|
Dicer2-loqspd-dsrna complex at mid-translocation state
. SNAP output
|
|
7w0e
|
RNA binding protein |
cryo-EM (4.03 Å) |
Su S, Wang J, Deng T, Yuan X, He J, Liu N, Li X,
Huang Y, Wang HW, Ma J |
(2022) "Structural
insights into dsRNA processing by Drosophila
Dicer-2-Loqs-PD." Nature,
607, 399-406. doi: 10.1038/s41586-022-04911-x.
|
Dmdicer2-loqspd-dsrna active-dicing status . SNAP output
|
|
7w0f
|
RNA binding protein |
cryo-EM (4.55 Å) |
Su S, Wang J, Deng T, Yuan X, He J, Liu N, Li X,
Huang Y, Wang HW, Ma J |
(2022) "Structural
insights into dsRNA processing by Drosophila
Dicer-2-Loqs-PD." Nature,
607, 399-406. doi: 10.1038/s41586-022-04911-x.
|
Dmdicer2-loqspd-dsrna post-dicing status . SNAP output
|
|
7w59
|
splicing |
cryo-EM (3.6 Å) |
Zhan X, Lu Y, Zhang X, Yan C, Shi Y |
(2022) "Mechanism
of exon ligation by human spliceosome."
Mol.Cell, 82, 2769-2778.e4.
doi: 10.1016/j.molcel.2022.05.021.
|
The cryo-EM structure of human pre-c*-i complex .
SNAP output
|
|
7w5a
|
splicing |
cryo-EM (3.6 Å) |
Zhan X, Lu Y, Zhang X, Yan C, Shi Y |
(2022) "Mechanism
of exon ligation by human spliceosome."
Mol.Cell, 82, 2769-2778.e4.
doi: 10.1016/j.molcel.2022.05.021.
|
The cryo-EM structure of human pre-c*-ii complex .
SNAP output
|
|
7w5b
|
splicing |
cryo-EM (4.3 Å) |
Zhan X, Lu Y, Zhang X, Yan C, Shi Y |
(2022) "Mechanism
of exon ligation by human spliceosome."
Mol.Cell, 82, 2769-2778.e4.
doi: 10.1016/j.molcel.2022.05.021.
|
The cryo-EM structure of human c* complex . SNAP output
|
|
7w9s
|
transferase-RNA |
X-ray (2.53 Å) |
Li R, Wang M, Gong P |
(2022) "Crystal
structure of a pre-chemistry viral RNA-dependent RNA
polymerase suggests participation of two basic residues
in catalysis." Nucleic Acids Res.,
50, 12389-12399. doi: 10.1093/nar/gkac1133.
|
Crystal structure of the enterovirus 71 polymerase
elongation complex (c1s3 form) . SNAP output
|
|
7wah
|
RNA binding protein-RNA |
cryo-EM (2.45 Å) |
Kato K, Zhou W, Okazaki S, Isayama Y, Nishizawa T,
Gootenberg JS, Abudayyeh OO, Nishimasu H |
(2022) "Structure
and engineering of the type III-E CRISPR-Cas7-11
effector complex." Cell,
185, 2324-2337.e16. doi: 10.1016/j.cell.2022.05.003.
|
Structure of cas7-11 in complex with guide RNA and
target RNA . SNAP
output
|
|
7wkp
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Zhang M, Peng R, Peng Q, Liu S, Li Z, Zhang Y, Song
H, Yang J, Xing X, Wang P, Qi J, Gao GF |
(2023) "Mechanistic
insights into DNA binding and cleavage by a compact
type I-F CRISPR-Cas system in bacteriophage."
Proc.Natl.Acad.Sci.USA, 120,
e2215098120. doi: 10.1073/pnas.2215098120.
|
Icp1 csy4 . SNAP
output
|
|
7wkv
|
oxidoreductase-RNA |
X-ray (2.1 Å) |
Kaur S, Tam NY, McDonough MA, Schofield CJ, Aik
WS |
(2022) "Mechanisms
of substrate recognition and N6-methyladenosine
demethylation revealed by crystal structures of
ALKBH5-RNA complexes." Nucleic Acids Res.,
50, 4148-4160. doi: 10.1093/nar/gkac195.
|
Crystal structure of human alkbh5 in complex with
2-oxoglutarate (2og) and m6a-containing ssrna .
SNAP output
|
|
7wl0
|
oxidoreductase-RNA |
X-ray (2.5 Å) |
Kaur S, Tam NY, McDonough MA, Schofield CJ, Aik
WS |
(2022) "Mechanisms
of substrate recognition and N6-methyladenosine
demethylation revealed by crystal structures of
ALKBH5-RNA complexes." Nucleic Acids Res.,
50, 4148-4160. doi: 10.1093/nar/gkac195.
|
Crystal structure of human alkbh5 in complex with
n-oxalylglycine (nog) and m6a-containing ssrna .
SNAP output
|
|
7wm4
|
immune system-RNA |
cryo-EM (3.2 Å) |
Sakaniwa K, Fujimura A, Shibata T, Shigematsu H,
Ekimoto T, Yamamoto M, Ikeguchi M, Miyake K, Ohto U,
Shimizu T |
(2023) "TLR3
forms a laterally aligned multimeric complex along
double-stranded RNA for efficient signal
transduction." Nat Commun,
14, 164. doi: 10.1038/s41467-023-35844-2.
|
cryo-EM structure of tetrameric tlr3 in complex with
dsrna (90 bp) . SNAP
output
|
|
7wnu
|
RNA binding protein-RNA |
X-ray (3.2 Å) |
Bao L, Hu J, Zhan B, Chi M, Li Z, Wang S, Shan C,
Zhao Z, Guo Y, Ding X, Ji C, Tao S, Ni T, Zhang X, Zhao
G, Li J |
(2023) "Structural insights into RNase J that plays an
essential role in Mycobacterium tuberculosis RNA
metabolism." Nat Commun, 14,
2280. doi: 10.1038/s41467-023-38045-z.
|
Mycobacterium tuberculosis rnase j complex with 7nt RNA
. SNAP output
|
|
7wtl
|
ribosome |
cryo-EM (3.3 Å) |
Cheng J, La Venuta G, Lau B, Berninghausen O,
Beckmann R, Hurt E |
(2022) "In vitro
structural maturation of an early stage pre-40S
particle coupled with U3 snoRNA release and central
pseudoknot formation." Nucleic Acids Res.,
50, 11916-11923. doi: 10.1093/nar/gkac910.
|
cryo-EM structure of a yeast pre-40s ribosomal subunit
- state dis-d . SNAP
output
|
|
7wtm
|
ribosome |
cryo-EM (3.5 Å) |
Cheng J, La Venuta G, Lau B, Berninghausen O,
Beckmann R, Hurt E |
(2022) "In vitro
structural maturation of an early stage pre-40S
particle coupled with U3 snoRNA release and central
pseudoknot formation." Nucleic Acids Res.,
50, 11916-11923. doi: 10.1093/nar/gkac910.
|
cryo-EM structure of a yeast pre-40s ribosomal subunit
- state dis-e . SNAP
output
|
|
7wtn
|
ribosome |
cryo-EM (3.4 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a yeast pre-40s ribosomal subunit
- state tsr1-1 (with rps2) . SNAP output
|
|
7wto
|
ribosome |
cryo-EM (3.5 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a yeast pre-40s ribosomal subunit
- state tsr1-1 (without rps2) . SNAP output
|
|
7wtp
|
ribosome |
cryo-EM (3.8 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a yeast pre-40s ribosomal subunit
- state tsr1-2 (with rps2) . SNAP output
|
|
7wtq
|
ribosome |
cryo-EM (3.7 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a yeast pre-40s ribosomal subunit
- state tsr1-2 (without rps2) . SNAP output
|
|
7wtr
|
ribosome |
cryo-EM (3.5 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a yeast pre-40s ribosomal subunit
- state tsr1-3 . SNAP
output
|
|
7wts
|
ribosome |
cryo-EM (3.2 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a human pre-40s ribosomal subunit
- state utp14 . SNAP
output
|
|
7wtt
|
ribosome |
cryo-EM (3.1 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a human pre-40s ribosomal subunit
- state rrp12-a1 (with ck1) . SNAP output
|
|
7wtu
|
ribosome |
cryo-EM (3.0 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a human pre-40s ribosomal subunit
- state rrp12-a1 (without ck1) . SNAP output
|
|
7wtv
|
ribosome |
cryo-EM (3.5 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a human pre-40s ribosomal subunit
- state rrp12-a2 . SNAP
output
|
|
7wtw
|
ribosome |
cryo-EM (3.2 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a human pre-40s ribosomal subunit
- state rrp12-a3 . SNAP
output
|
|
7wtx
|
ribosome |
cryo-EM (3.1 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a human pre-40s ribosomal subunit
- state rrp12-b1 . SNAP
output
|
|
7wtz
|
ribosome |
cryo-EM (3.0 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a human pre-40s ribosomal subunit
- state rrp12-b2 . SNAP
output
|
|
7wu0
|
ribosome |
cryo-EM (3.3 Å) |
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen
O, Hurt E, Beckmann R |
(2022) "The
nucleoplasmic phase of pre-40S formation prior to
nuclear export." Nucleic Acids Res.,
50, 11924-11937. doi: 10.1093/nar/gkac961.
|
cryo-EM structure of a human pre-40s ribosomal subunit
- state rrp12-b3 . SNAP
output
|
|
7wv3
|
immune system-RNA |
cryo-EM (2.26 Å) |
Lim CS, Jang YH, Lee GY, Han GM, Jeong HJ, Kim JW,
Lee JO |
(2022) "TLR3
forms a highly organized cluster when bound to a
poly(I:C) RNA ligand." Nat Commun,
13, 6876. doi: 10.1038/s41467-022-34602-0.
|
Toll-like receptor3 linear cluster . SNAP output
|
|
7wv4
|
immune system-RNA |
cryo-EM (3.35 Å) |
Lim CS, Jang YH, Lee GY, Han GM, Jeong HJ, Kim JW,
Lee JO |
(2022) "TLR3
forms a highly organized cluster when bound to a
poly(I:C) RNA ligand." Nat Commun,
13, 6876. doi: 10.1038/s41467-022-34602-0.
|
Ectotlr3-poly(i:c) cluster . SNAP output
|
|
7wv5
|
immune system-RNA |
cryo-EM (3.1 Å) |
Lim CS, Jang YH, Lee GY, Han GM, Jeong HJ, Kim JW,
Lee JO |
(2022) "TLR3
forms a highly organized cluster when bound to a
poly(I:C) RNA ligand." Nat Commun,
13, 6876. doi: 10.1038/s41467-022-34602-0.
|
Ectotlr3-poly(i:c) . SNAP output
|
|
7wve
|
immune system-RNA |
cryo-EM (3.11 Å) |
Lim CS, Jang YH, Lee GY, Han GM, Jeong HJ, Kim JW,
Lee JO |
(2022) "TLR3
forms a highly organized cluster when bound to a
poly(I:C) RNA ligand." Nat Commun,
13, 6876. doi: 10.1038/s41467-022-34602-0.
|
Ct-mut (d523k,d524k,e527k) tlr3-poly(i:c) complex .
SNAP output
|
|
7wvf
|
immune system-RNA |
cryo-EM (3.91 Å) |
Lim CS, Jang YH, Lee GY, Han GM, Jeong HJ, Kim JW,
Lee JO |
(2022) "TLR3
forms a highly organized cluster when bound to a
poly(I:C) RNA ligand." Nat Commun,
13, 6876. doi: 10.1038/s41467-022-34602-0.
|
Ectotlr3-mab12-poly(i:c) complex . SNAP output
|
|
7wvj
|
immune system-RNA |
cryo-EM (3.26 Å) |
Lim CS, Jang YH, Lee GY, Han GM, Jeong HJ, Kim JW,
Lee JO |
(2022) "TLR3
forms a highly organized cluster when bound to a
poly(I:C) RNA ligand." Nat Commun,
13, 6876. doi: 10.1038/s41467-022-34602-0.
|
Nt-mut(k117d,k139d,k145d) tlr3 -poly i:c complex .
SNAP output
|
|
7wwu
|
RNA binding protein-RNA |
cryo-EM (3.5 Å) |
Zhang M, Peng R, Peng Q, Liu S, Li Z, Zhang Y, Song
H, Yang J, Xing X, Wang P, Qi J, Gao GF |
(2023) "Mechanistic
insights into DNA binding and cleavage by a compact
type I-F CRISPR-Cas system in bacteriophage."
Proc.Natl.Acad.Sci.USA, 120,
e2215098120. doi: 10.1073/pnas.2215098120.
|
Icp1 csy complex . SNAP
output
|
|
7x34
|
translation-RNA |
cryo-EM (3.1 Å) |
Chen Y, Tsai B, Li N, Gao N |
(2022) "Structural
remodeling of ribosome associated Hsp40-Hsp70
chaperones during co-translational folding."
Nat Commun, 13, 3410. doi:
10.1038/s41467-022-31127-4.
|
cryo-EM structure of rnc-rac complex in presence of ssb
from s. cerevisiae 2 . SNAP output
|
|
7x7a
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Yu G, Wang X, Zhang Y, An Q, Wen Y, Li X, Yin H, Deng
Z, Zhang H |
(2022) "Structure
and function of a bacterial type III-E CRISPR-Cas7-11
complex." Nat Microbiol,
7, 2078-2088. doi: 10.1038/s41564-022-01256-z.
|
cryo-EM structure of sbcas7-11 in complex with crrna
and target RNA . SNAP
output
|
|
7x7r
|
RNA-RNA binding protein |
cryo-EM (3.5 Å) |
Yu G, Wang X, Zhang Y, An Q, Wen Y, Li X, Yin H, Deng
Z, Zhang H |
(2022) "Structure
and function of a bacterial type III-E CRISPR-Cas7-11
complex." Nat Microbiol,
7, 2078-2088. doi: 10.1038/s41564-022-01256-z.
|
cryo-EM structure of a bacterial protein . SNAP output
|
|
7x8a
|
RNA binding protein-RNA |
cryo-EM (2.8 Å) |
Yu G, Wang X, Zhang Y, An Q, Wen Y, Li X, Yin H, Deng
Z, Zhang H |
(2022) "Structure
and function of a bacterial type III-E CRISPR-Cas7-11
complex." Nat Microbiol,
7, 2078-2088. doi: 10.1038/s41564-022-01256-z.
|
cryo-EM structure of a bacterial protein complex .
SNAP output
|
|
7xam
|
ribosome |
cryo-EM (3.5 Å) |
Baid P, Sengupta J |
(2023) "Cryo-EM
captures a unique conformational rearrangement in 23S
rRNA helices of the Mycobacterium 50S subunit."
Int.J.Biol.Macromol., 253,
126876. doi: 10.1016/j.ijbiomac.2023.126876.
|
Mycobacterium smegmatis 50s ribosomal subunit from
stationary phase of growth . SNAP output
|
|
7xc7
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Yu G, Wang X, Zhang Y, An Q, Wen Y, Li X, Yin H, Deng
Z, Zhang H |
(2022) "Structure
and function of a bacterial type III-E CRISPR-Cas7-11
complex." Nat Microbiol,
7, 2078-2088. doi: 10.1038/s41564-022-01256-z.
|
cryo-EM structure of a bacterial protein complex .
SNAP output
|
|
7xd8
|
transferase-RNA |
X-ray (2.85 Å) |
Wu J, Wang X, Liu Q, Lu G, Gong P |
(2023) "Structural
basis of transition from initiation to elongation in de
novo viral RNA-dependent RNA polymerases."
Proc.Natl.Acad.Sci.USA, 120,
e2211425120. doi: 10.1073/pnas.2211425120.
|
Crystal structure of dengue virus serotype 2 (denv2)
polymerase elongation complex (native form) . SNAP output
|
|
7xd9
|
transferase-RNA |
X-ray (2.58 Å) |
Wu J, Wang X, Liu Q, Lu G, Gong P |
(2023) "Structural
basis of transition from initiation to elongation in de
novo viral RNA-dependent RNA polymerases."
Proc.Natl.Acad.Sci.USA, 120,
e2211425120. doi: 10.1073/pnas.2211425120.
|
Crystal structure of dengue virus serotype 2 (denv2)
polymerase elongation complex (ctp form) . SNAP output
|
|
7xg1
|
structural protein-RNA |
cryo-EM (3.3 Å) |
Cui N, Zhang JT, Liu Y, Liu Y, Liu XY, Wang C, Huang
H, Jia N |
(2023) "Type IV-A CRISPR-Csf complex: Assembly, dsDNA
targeting, and CasDinG recruitment." Mol.Cell,
83, 2493. doi: 10.1016/j.molcel.2023.05.036.
|
Cryoem structure of type iv-a csf-crrna binary complex
. SNAP output
|
|
7xjz
|
ligase-RNA |
cryo-EM (3.9 Å) |
Yu Z, Wu Z, Li Y, Hao Q, Cao X, Blaha GM, Lin J, Lu
G |
(2023) "Structural
basis of a two-step tRNA recognition mechanism for
plastid glycyl-tRNA synthetase." Nucleic Acids
Res., 51, 4000-4011. doi:
10.1093/nar/gkad144.
|
cryo-EM strucrture of oryza sativa plastid glycyl-trna
synthetase in complex with trna (trna binding state) .
SNAP output
|
|
7xk0
|
ligase-RNA |
cryo-EM (3.59 Å) |
Yu Z, Wu Z, Li Y, Hao Q, Cao X, Blaha GM, Lin J, Lu
G |
(2023) "Structural
basis of a two-step tRNA recognition mechanism for
plastid glycyl-tRNA synthetase." Nucleic Acids
Res., 51, 4000-4011. doi:
10.1093/nar/gkad144.
|
cryo-EM strucrture of oryza sativa plastid glycyl-trna
synthetase in complex with trna (trna locked state) .
SNAP output
|
|
7xk1
|
ligase-RNA |
cryo-EM (4.3 Å) |
Yu Z, Wu Z, Li Y, Hao Q, Cao X, Blaha GM, Lin J, Lu
G |
(2023) "Structural
basis of a two-step tRNA recognition mechanism for
plastid glycyl-tRNA synthetase." Nucleic Acids
Res., 51, 4000-4011. doi:
10.1093/nar/gkad144.
|
cryo-EM structure of oryza sativa plastid glycyl-trna
synthetase in complex with two trnas (both in trna
binding states) . SNAP
output
|
|
7xpg
|
virus like particle |
cryo-EM (3.51 Å) |
Chen NC, Wang CH, Yoshimura M, Yeh YQ, Guan HH,
Chuankhayan P, Lin CC, Lin PJ, Huang YC, Wakatsuki S, Ho
MC, Chen CJ |
(2023) "Structures
of honeybee-infecting Lake Sinai virus reveal domain
functions and capsid assembly with dynamic
motions." Nat Commun, 14,
545. doi: 10.1038/s41467-023-36235-3.
|
cryo-EM structure of the t=3 lake sinai virus 1
(delta-n48) virus-like capsid at ph 6.5 . SNAP output
|
|
7xpl
|
RNA binding protein-RNA |
X-ray (2.213 Å) |
Wang J, Yang Z, Ye K |
(2022) "Methylation
guide RNAs without box C/D motifs." Rna,
28, 1597-1605. doi: 10.1261/rna.079379.122.
|
Crystal structure of a c-d-free RNA-guided RNA
2'-o-methyltransferase . SNAP output
|
|
7xs4
|
plant protein-RNA |
X-ray (1.846 Å) |
Hu Q, Yang H, Li M, Zhu L, Lv M, Li F, Zhang Z, Ren
G, Gong Q |
(2022) "Molecular
mechanism underlying the di-uridylation activity of
Arabidopsis TUTase URT1." Nucleic Acids
Res., 50, 10614-10625. doi:
10.1093/nar/gkac839.
|
Crystal structure of urt1 in complex with aaau RNA .
SNAP output
|
|
7xso
|
immune system-RNA |
cryo-EM (3.01 Å) |
Liu X, Zhang L, Wang H, Xiu Y, Huang L, Gao Z, Li N,
Li F, Xiong W, Gao T, Zhang Y, Yang M, Feng Y |
(2022) "Target
RNA activates the protease activity of Craspase to
confer antiviral defense." Mol.Cell,
82, 4503-4518.e8. doi: 10.1016/j.molcel.2022.10.007.
|
Structure of the type iii-e crispr-cas effector gramp .
SNAP output
|
|
7xsp
|
immune system-RNA |
cryo-EM (2.89 Å) |
Liu X, Zhang L, Wang H, Xiu Y, Huang L, Gao Z, Li N,
Li F, Xiong W, Gao T, Zhang Y, Yang M, Feng Y |
(2022) "Target
RNA activates the protease activity of Craspase to
confer antiviral defense." Mol.Cell,
82, 4503-4518.e8. doi: 10.1016/j.molcel.2022.10.007.
|
Structure of gramp-target RNA . SNAP output
|
|
7xsq
|
immune system-RNA |
cryo-EM (2.88 Å) |
Liu X, Zhang L, Wang H, Xiu Y, Huang L, Gao Z, Li N,
Li F, Xiong W, Gao T, Zhang Y, Yang M, Feng Y |
(2022) "Target
RNA activates the protease activity of Craspase to
confer antiviral defense." Mol.Cell,
82, 4503-4518.e8. doi: 10.1016/j.molcel.2022.10.007.
|
Structure of the craspase . SNAP output
|
|
7xsr
|
immune system-RNA |
cryo-EM (2.97 Å) |
Liu X, Zhang L, Wang H, Xiu Y, Huang L, Gao Z, Li N,
Li F, Xiong W, Gao T, Zhang Y, Yang M, Feng Y |
(2022) "Target
RNA activates the protease activity of Craspase to
confer antiviral defense." Mol.Cell,
82, 4503-4518.e8. doi: 10.1016/j.molcel.2022.10.007.
|
Structure of craspase-target RNA . SNAP output
|
|
7xss
|
immune system-RNA |
cryo-EM (3.2 Å) |
Liu X, Zhang L, Wang H, Xiu Y, Huang L, Gao Z, Li N,
Li F, Xiong W, Gao T, Zhang Y, Yang M, Feng Y |
(2022) "Target
RNA activates the protease activity of Craspase to
confer antiviral defense." Mol.Cell,
82, 4503-4518.e8. doi: 10.1016/j.molcel.2022.10.007.
|
Structure of craspase-ctr . SNAP output
|
|
7xt4
|
immune system-RNA |
cryo-EM (3.08 Å) |
Liu X, Zhang L, Wang H, Xiu Y, Huang L, Gao Z, Li N,
Li F, Xiong W, Gao T, Zhang Y, Yang M, Feng Y |
(2022) "Target
RNA activates the protease activity of Craspase to
confer antiviral defense." Mol.Cell,
82, 4503-4518.e8. doi: 10.1016/j.molcel.2022.10.007.
|
Structure of craspase-ntr . SNAP output
|
|
7xw2
|
gene regulation-RNA |
cryo-EM (3.04 Å) |
Lee YY, Lee H, Kim H, Kim VN, Roh SH |
(2023) "Structure
of the human DICER-pre-miRNA complex in a dicing
state." Nature, 615,
331-338. doi: 10.1038/s41586-023-05723-3.
|
cryo-EM structure of human dicer-pre-mirna in a dicing
state . SNAP output
|
|
7xwz
|
viral protein-DNA |
X-ray (2.25 Å) |
Luan X, Li X, Li Y, Su G, Yin W, Jiang Y, Xu N, Wang
F, Cheng W, Jin Y, Zhang L, Xu HE, Xue Y, Zhang S |
(2022) "Antiviral
drug design based on structural insights into the
N-terminal domain and C-terminal domain of the
SARS-CoV-2 nucleocapsid protein." Sci Bull
(Beijing), 67, 2327-2335. doi:
10.1016/j.scib.2022.10.021.
|
Crystal structure of sars-cov-2 n-ntd and dsrna complex
. SNAP output
|
|
7y38
|
viral protein-RNA |
cryo-EM (2.8 Å) |
Tan YB, Chmielewski D, Law MCY, Zhang K, He Y, Chen
M, Jin J, Luo D |
(2022) "Molecular
architecture of the Chikungunya virus replication
complex." Sci Adv, 8,
eadd2536. doi: 10.1126/sciadv.add2536.
|
Molecular architecture of the chikungunya virus
replication complex . SNAP output
|
|
7y41
|
ribosome |
cryo-EM (4.1 Å) |
Baid P, Sengupta J |
(2023) "Cryo-EM
captures a unique conformational rearrangement in 23S
rRNA helices of the Mycobacterium 50S subunit."
Int.J.Biol.Macromol., 253,
126876. doi: 10.1016/j.ijbiomac.2023.126876.
|
Mycobacterium smegmatis 50s ribosomal subunit from log
phase of growth . SNAP
output
|
|
7y7c
|
ribosome |
cryo-EM (2.51 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the bacterial ribosome with human trna
asp(g34) and mrna(gau) . SNAP output
|
|
7y7d
|
ribosome |
cryo-EM (2.58 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the bacterial ribosome with human trna
asp(q34) and mrna(gau) . SNAP output
|
|
7y7e
|
ribosome |
cryo-EM (2.41 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the bacterial ribosome with human trna
asp(manq34) and mrna(gau) . SNAP output
|
|
7y7f
|
ribosome |
cryo-EM (2.43 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the bacterial ribosome with human trna
asp(manq34) and mrna(gac) . SNAP output
|
|
7y7g
|
ribosome |
cryo-EM (2.34 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the bacterial ribosome with human trna
tyr(galq34) and mrna(uau) . SNAP output
|
|
7y7h
|
ribosome |
cryo-EM (2.51 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the bacterial ribosome with human trna
tyr(galq34) and mrna(uac) . SNAP output
|
|
7y7p
|
RNA binding protein |
X-ray (2.7 Å) |
Cui R, Li H, Zhao J, Li X, Gan J, Ma J |
(2022) "Structural
insights into the dual activities of the two-barrel RNA
polymerase QDE-1." Nucleic Acids Res.,
50, 10169-10186. doi: 10.1093/nar/gkac727.
|
Qde-1 in complex with RNA template, RNA primer and
ampnpp . SNAP output
|
|
7y7q
|
RNA binding protein |
X-ray (2.05 Å) |
Cui R, Li H, Zhao J, Li X, Gan J, Ma J |
(2022) "Structural
insights into the dual activities of the two-barrel RNA
polymerase QDE-1." Nucleic Acids Res.,
50, 10169-10186. doi: 10.1093/nar/gkac727.
|
Qde-1 in complex with RNA template, RNA primer and
3'-dgtp . SNAP
output
|
|
7y80
|
structural protein-RNA |
cryo-EM (2.71 Å) |
Cui N, Zhang JT, Li Z, Liu XY, Wang C, Huang H, Jia
N |
(2022) "Structural
basis for the non-self RNA-activated protease activity
of the type III-E CRISPR nuclease-protease
Craspase." Nat Commun,
13, 7549. doi: 10.1038/s41467-022-35275-5.
|
Cryoem structure of type iii-e crispr craspase
gramp-crrna binary complex . SNAP output
|
|
7y81
|
structural protein-RNA |
cryo-EM (2.54 Å) |
Cui N, Zhang JT, Li Z, Liu XY, Wang C, Huang H, Jia
N |
(2022) "Structural
basis for the non-self RNA-activated protease activity
of the type III-E CRISPR nuclease-protease
Craspase." Nat Commun,
13, 7549. doi: 10.1038/s41467-022-35275-5.
|
Cryoem structure of type iii-e crispr craspase
gramp-crrna complex bound to non-self RNA target .
SNAP output
|
|
7y82
|
RNA binding protein |
cryo-EM (2.83 Å) |
Cui N, Zhang JT, Li Z, Liu XY, Wang C, Huang H, Jia
N |
(2022) "Structural
basis for the non-self RNA-activated protease activity
of the type III-E CRISPR nuclease-protease
Craspase." Nat Commun,
13, 7549. doi: 10.1038/s41467-022-35275-5.
|
Cryoem structure of type iii-e crispr craspase
gramp-crrna complex bound to self RNA target . SNAP output
|
|
7y83
|
structural protein-RNA |
cryo-EM (2.93 Å) |
Cui N, Zhang JT, Li Z, Liu XY, Wang C, Huang H, Jia
N |
(2022) "Structural
basis for the non-self RNA-activated protease activity
of the type III-E CRISPR nuclease-protease
Craspase." Nat Commun,
13, 7549. doi: 10.1038/s41467-022-35275-5.
|
Cryoem structure of type iii-e crispr craspase
gramp-crrna in complex with tpr-chat protease bound to
non-self RNA target . SNAP output
|
|
7y84
|
structural protein-RNA |
cryo-EM (2.61 Å) |
Cui N, Zhang JT, Li Z, Liu XY, Wang C, Huang H, Jia
N |
(2022) "Structural
basis for the non-self RNA-activated protease activity
of the type III-E CRISPR nuclease-protease
Craspase." Nat Commun,
13, 7549. doi: 10.1038/s41467-022-35275-5.
|
Cryoem structure of type iii-e crispr craspase
gramp-crrna in complex with tpr-chat protease .
SNAP output
|
|
7y85
|
structural protein-RNA |
cryo-EM (2.73 Å) |
Cui N, Zhang JT, Li Z, Liu XY, Wang C, Huang H, Jia
N |
(2022) "Structural
basis for the non-self RNA-activated protease activity
of the type III-E CRISPR nuclease-protease
Craspase." Nat Commun,
13, 7549. doi: 10.1038/s41467-022-35275-5.
|
Cryoem structure of type iii-e crispr craspase
gramp-crrna in complex with tpr-chat protease bound to
self RNA target . SNAP
output
|
|
7y8t
|
immune system-RNA |
cryo-EM (2.9 Å) |
Wang S, Guo M, Zhu Y, Lin Z, Huang Z |
(2022) "Cryo-EM
structure of the type III-E CRISPR-Cas effector gRAMP
in complex with TPR-CHAT." Cell Res.,
32, 1128-1131. doi: 10.1038/s41422-022-00738-3.
|
Structure of cas7-11-crrna in complex with tpr-chat .
SNAP output
|
|
7y8y
|
immune system-RNA |
cryo-EM (3.0 Å) |
Wang S, Guo M, Zhu Y, Lin Z, Huang Z |
(2022) "Cryo-EM
structure of the type III-E CRISPR-Cas effector gRAMP
in complex with TPR-CHAT." Cell Res.,
32, 1128-1131. doi: 10.1038/s41422-022-00738-3.
|
Structure of cas7-11-crrna-tgrna in complex with
tpr-chat . SNAP
output
|
|
7y9x
|
RNA binding protein-RNA |
cryo-EM (2.49 Å) |
Kato K, Okazaki S, Schmitt-Ulms C, Jiang K, Zhou W,
Ishikawa J, Isayama Y, Adachi S, Nishizawa T, Makarova
KS, Koonin EV, Abudayyeh OO, Gootenberg JS, Nishimasu
H |
(2022) "RNA-triggered
protein cleavage and cell growth arrest by the type
III-E CRISPR nuclease-protease." Science,
378, 882-889. doi: 10.1126/science.add7347.
|
Structure of the cas7-11-csx29-guide RNA complex .
SNAP output
|
|
7y9y
|
RNA binding protein-RNA |
cryo-EM (2.77 Å) |
Kato K, Okazaki S, Schmitt-Ulms C, Jiang K, Zhou W,
Ishikawa J, Isayama Y, Adachi S, Nishizawa T, Makarova
KS, Koonin EV, Abudayyeh OO, Gootenberg JS, Nishimasu
H |
(2022) "RNA-triggered
protein cleavage and cell growth arrest by the type
III-E CRISPR nuclease-protease." Science,
378, 882-889. doi: 10.1126/science.add7347.
|
Structure of the cas7-11-csx29-guide RNA-target RNA (no
pfs) complex . SNAP
output
|
|
7yed
|
viral protein-RNA |
cryo-EM (3.0 Å) |
Bao K, Zhang X, Li D, Sun W, Sun Z, Wang J, Zhu
P |
(2022) "In situ
structures of polymerase complex of mammalian reovirus
illuminate RdRp activation and transcription
regulation." Proc.Natl.Acad.Sci.USA,
119, e2203054119. doi: 10.1073/pnas.2203054119.
|
In situ structure of polymerase complex of mammalian
reovirus in the elongation state . SNAP output
|
|
7yew
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Li X, Guo W, Wen Y, Meng C, Zhang Q, Chen H, Zhao X,
Wu B |
(2025) "Structural
basis for the RNA binding properties of mouse
IGF2BP3." Structure. doi: 10.1016/j.str.2025.01.022.
|
Structure of mmigf2bp3 in complex with 7-mer RNA .
SNAP output
|
|
7yex
|
RNA binding protein-RNA |
X-ray (2.0 Å) |
Li X, Guo W, Wen Y, Meng C, Zhang Q, Chen H, Zhao X,
Wu B |
(2025) "Structural
basis for the RNA binding properties of mouse
IGF2BP3." Structure. doi: 10.1016/j.str.2025.01.022.
|
Structure of mmigf2bp3 in complex with 8-mer RNA .
SNAP output
|
|
7yey
|
RNA binding protein-RNA |
X-ray (1.85 Å) |
Li X, Guo W, Wen Y, Meng C, Zhang Q, Chen H, Zhao X,
Wu B |
(2025) "Structural
basis for the RNA binding properties of mouse
IGF2BP3." Structure. doi: 10.1016/j.str.2025.01.022.
|
Structure of mmigf2bp3-kh12 in complex with 8-mer RNA .
SNAP output
|
|
7yfe
|
viral protein-RNA |
cryo-EM (3.4 Å) |
Bao K, Zhang X, Li D, Sun W, Sun Z, Wang J, Zhu
P |
(2022) "In situ
structures of polymerase complex of mammalian reovirus
illuminate RdRp activation and transcription
regulation." Proc.Natl.Acad.Sci.USA,
119, e2203054119. doi: 10.1073/pnas.2203054119.
|
In situ structure of polymerase complex of mammalian
reovirus in virion . SNAP output
|
|
7yfq
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue
J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S,
Zhang Z, Song CQ, Wu J, Shen EZ |
(2024) "Mammalian
PIWI-piRNA-target complexes reveal features for broad
and efficient target silencing."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-024-01287-6.
|
cryo-EM structure of the efpiwi (n959k)-pirna-target
ternary complex . SNAP
output
|
|
7yfx
|
RNA binding protein-RNA |
cryo-EM (3.4 Å) |
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue
J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S,
Zhang Z, Song CQ, Wu J, Shen EZ |
(2024) "Mammalian
PIWI-piRNA-target complexes reveal features for broad
and efficient target silencing."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-024-01287-6.
|
cryo-EM structure of hili in complex with pirna .
SNAP output
|
|
7yfy
|
RNA binding protein-RNA |
cryo-EM (3.4 Å) |
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue
J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S,
Zhang Z, Song CQ, Wu J, Shen EZ |
(2024) "Mammalian
PIWI-piRNA-target complexes reveal features for broad
and efficient target silencing."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-024-01287-6.
|
cryo-EM structure of the mili-pirna- target ternary
complex . SNAP
output
|
|
7yg6
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue
J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S,
Zhang Z, Song CQ, Wu J, Shen EZ |
(2024) "Mammalian
PIWI-piRNA-target complexes reveal features for broad
and efficient target silencing."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-024-01287-6.
|
cryo-EM structure of the efpiwi(n959k) in complex with
pirna . SNAP output
|
|
7yg7
|
virus like particle-RNA |
cryo-EM (3.7 Å) |
Wang ZX, Liu B, Yang T, Yu D, Zhang C, Zheng L, Xie
J, Liu B, Liu M, Peng H, Lai L, Ouyang Q, Ouyang S, Zhang
YA |
(2023) "Structure
of the Spring Viraemia of Carp Virus Ribonucleoprotein
Complex Reveals Its Assembly Mechanism and Application
in Antiviral Drug Screening." J.Virol.,
97, e0182922. doi: 10.1128/jvi.01829-22.
|
Structure of the spring viraemia of carp virus
ribonucleoprotein complex . SNAP output
|
|
7ygh
|
hydrolase |
X-ray (3.11 Å) |
Du L, Zhang D, Luo Z, Lin Z |
(2023) "Molecular
basis of stepwise cyclic tetra-adenylate cleavage by
the type III CRISPR ring nuclease Crn1/Sso2081."
Nucleic Acids Res., 51,
2485-2495. doi: 10.1093/nar/gkad101.
|
Crystal structure of the ring nuclease sso2081 from
saccharolobus solfataricus in complex with
cyclic-tetraadenylate (ca4) . SNAP output
|
|
7ygl
|
hydrolase |
X-ray (2.5 Å) |
Du L, Zhang D, Luo Z, Lin Z |
(2023) "Molecular
basis of stepwise cyclic tetra-adenylate cleavage by
the type III CRISPR ring nuclease Crn1/Sso2081."
Nucleic Acids Res., 51,
2485-2495. doi: 10.1093/nar/gkad101.
|
Crystal structure of the ring nuclease sso2081 from
saccharolobus solfataricus in complex with a4>p
cleavage intermediate . SNAP output
|
|
7ygn
|
RNA binding protein-RNA |
cryo-EM (3.0 Å) |
Li Z, Li Z, Zhang Y, Zhou L, Xu Q, Li L, Zeng L, Xue
J, Niu H, Zhong J, Yu Q, Li D, Gui M, Huang Y, Tu S,
Zhang Z, Song CQ, Wu J, Shen EZ |
(2024) "Mammalian
PIWI-piRNA-target complexes reveal features for broad
and efficient target silencing."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-024-01287-6.
|
cryo-EM structure of the mili in complex with pirna .
SNAP output
|
|
7yla
|
ribosome |
cryo-EM (2.52 Å) |
Wu D, Dai Y, Gao N |
(2022) "Cryo-EM Structure of the 50S-HflX Complex
Reveals a Novel Mechanism of Antibiotic Resistance in
E. coli." Biorxiv. doi: 10.3969/j.issn.1000-6281.2023.04.007.
|
cryo-EM structure of 50s-hflx complex . SNAP output
|
|
7yn9
|
RNA binding protein |
cryo-EM (3.53 Å) |
Huo Y, Zhao H, Dong Q, Jiang T |
(2023) "Cryo-EM
structure and protease activity of the type III-E
CRISPR-Cas effector." Nat Microbiol,
8, 522-532. doi: 10.1038/s41564-022-01316-4.
|
cryo-EM structure of cas7-11-crrna binary complex .
SNAP output
|
|
7yna
|
RNA binding protein |
cryo-EM (3.64 Å) |
Huo Y, Zhao H, Dong Q, Jiang T |
(2023) "Cryo-EM
structure and protease activity of the type III-E
CRISPR-Cas effector." Nat Microbiol,
8, 522-532. doi: 10.1038/s41564-022-01316-4.
|
cryo-EM structure of cas7-11-crrna bound to target
RNA-1 . SNAP output
|
|
7ynb
|
RNA binding protein |
cryo-EM (3.46 Å) |
Huo Y, Zhao H, Dong Q, Jiang T |
(2023) "Cryo-EM
structure and protease activity of the type III-E
CRISPR-Cas effector." Nat Microbiol,
8, 522-532. doi: 10.1038/s41564-022-01316-4.
|
cryo-EM structure of cas7-11-crrna bound to target
RNA-2 . SNAP output
|
|
7ync
|
RNA binding protein |
cryo-EM (3.14 Å) |
Huo Y, Zhao H, Dong Q, Jiang T |
(2023) "Cryo-EM
structure and protease activity of the type III-E
CRISPR-Cas effector." Nat Microbiol,
8, 522-532. doi: 10.1038/s41564-022-01316-4.
|
cryo-EM structure of cas7-11-crrna bound to target
RNA-3 . SNAP output
|
|
7ynd
|
RNA binding protein |
cryo-EM (3.29 Å) |
Huo Y, Zhao H, Dong Q, Jiang T |
(2023) "Cryo-EM
structure and protease activity of the type III-E
CRISPR-Cas effector." Nat Microbiol,
8, 522-532. doi: 10.1038/s41564-022-01316-4.
|
cryo-EM structure of cas7-11-crrna-csx29 ternary
complex . SNAP
output
|
|
7ypw
|
viral protein |
cryo-EM (3.04 Å) |
Hu S, Fujita-Fujiharu Y, Sugita Y, Wendt L, Muramoto
Y, Nakano M, Hoenen T, Noda T |
(2023) "Cryoelectron
microscopic structure of the nucleoprotein-RNA complex
of the European filovirus, Lloviu virus." Pnas
Nexus, 2, pgad120. doi: 10.1093/pnasnexus/pgad120.
|
Lloviu cuevavirus nucleoprotein-RNA complex . SNAP output
|
|
7yr6
|
RNA binding protein-RNA |
cryo-EM (4.8 Å) |
Jia X, Pan Z, Yuan Y, Luo B, Luo Y, Mukherjee S, Jia
G, Liu L, Ling X, Yang X, Miao Z, Wei X, Bujnicki JM,
Zhao K, Su Z |
(2023) "Structural
basis of sRNA RsmZ regulation of Pseudomonas aeruginosa
virulence." Cell Res.,
33, 328-330. doi: 10.1038/s41422-023-00786-3.
|
cryo-EM structure of pseudomonas aeruginosa rsmz RNA in
complex with two rsma protein dimers . SNAP output
|
|
7yr7
|
RNA binding protein-RNA |
cryo-EM (3.8 Å) |
Jia X, Pan Z, Yuan Y, Luo B, Luo Y, Mukherjee S, Jia
G, Liu L, Ling X, Yang X, Miao Z, Wei X, Bujnicki JM,
Zhao K, Su Z |
(2023) "Structural
basis of sRNA RsmZ regulation of Pseudomonas aeruginosa
virulence." Cell Res.,
33, 328-330. doi: 10.1038/s41422-023-00786-3.
|
cryo-EM structure of pseudomonas aeruginosa rsmz RNA in
complex with three rsma protein dimers . SNAP output
|
|
7yr8
|
viral protein |
cryo-EM (3.2 Å) |
Hu S, Fujita-Fujiharu Y, Sugita Y, Wendt L, Muramoto
Y, Nakano M, Hoenen T, Noda T |
(2023) "Cryoelectron
microscopic structure of the nucleoprotein-RNA complex
of the European filovirus, Lloviu virus." Pnas
Nexus, 2, pgad120. doi: 10.1093/pnasnexus/pgad120.
|
Lloviu cuevavirus nucleoprotein(1-450 residues)-RNA
complex . SNAP
output
|
|
7yse
|
transferase-RNA |
X-ray (2.907 Å) |
Han L, Luo Z, Ju Y, Chen B, Zou T, Wang J, Xu J, Gu
Q, Yang XL, Schimmel P, Zhou H |
(2023) "The
binding mode of orphan glycyl-tRNA synthetase with tRNA
supports the synthetase classification and reveals
large domain movements." Sci Adv,
9, eadf1027. doi: 10.1126/sciadv.adf1027.
|
Crystal structure of e. coli heterotetrameric glyrs in
complex with trna . SNAP
output
|
|
7yym
|
RNA binding protein |
cryo-EM (4.19 Å) |
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek
K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F,
Jenickova I, Prochazkova M, Prochazka J, Pinkas M,
Novacek J, Joseph DF, Sedlacek R, Bernecky C, O'Carroll
D, Stefl R, Svoboda P |
(2022) "Structural
and functional basis of mammalian microRNA biogenesis
by Dicer." Mol.Cell, 82,
4064-4079.e13. doi: 10.1016/j.molcel.2022.10.010.
|
Mammalian dicer in the "pre-dicing state" with
pre-mir-15a substrate . SNAP output
|
|
7yyn
|
RNA binding protein |
cryo-EM (6.21 Å) |
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek
K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F,
Jenickova I, Prochazkova M, Prochazka J, Pinkas M,
Novacek J, Joseph DF, Sedlacek R, Bernecky C, O'Carroll
D, Stefl R, Svoboda P |
(2022) "Structural
and functional basis of mammalian microRNA biogenesis
by Dicer." Mol.Cell, 82,
4064-4079.e13. doi: 10.1016/j.molcel.2022.10.010.
|
Mammalian dicer in the dicing state with pre-mir-15a
substrate . SNAP
output
|
|
7z20
|
ribosome |
cryo-EM (2.29 Å) |
Ahn M, Wlodarski T, Mitropoulou A, Chan SHS, Sidhu H,
Plessa E, Becker TA, Budisa N, Waudby CA, Beckmann R,
Cassaignau AME, Cabrita LD, Christodoulou J |
(2022) "Modulating
co-translational protein folding by rational design and
ribosome engineering." Nat Commun,
13, 4243. doi: 10.1038/s41467-022-31906-z.
|
70s e. coli ribosome with an extended ul23 loop from
candidatus marinimicrobia and a stalled filamin domain
5 nascent chain . SNAP
output
|
|
7z26
|
RNA binding protein |
X-ray (1.9 Å) |
Nai F, Nachawati R, Zalesak F, Wang X, Li Y, Caflisch
A |
(2022) "Fragment
Ligands of the m 6 A-RNA Reader YTHDF2." Acs
Med.Chem.Lett., 13, 1500-1509.
doi: 10.1021/acsmedchemlett.2c00303.
|
Crystal structure of ythdf2 yth domain in complex with
m6a RNA . SNAP
output
|
|
7z34
|
ribosome |
cryo-EM (3.8 Å) |
Prattes M, Grishkovskaya I, Hodirnau VV,
Hetzmannseder C, Zisser G, Sailer C, Kargas V, Loibl M,
Gerhalter M, Kofler L, Warren AJ, Stengel F, Haselbach D,
Bergler H |
(2022) "Visualizing
maturation factor extraction from the nascent ribosome
by the AAA-ATPase Drg1."
Nat.Struct.Mol.Biol., 29,
942-953. doi: 10.1038/s41594-022-00832-5.
|
Structure of pre-60s particle bound to drg1(afg2). .
SNAP output
|
|
7z3n
|
chaperone |
cryo-EM (3.2 Å) |
Kisonaite M, Wild K, Lapouge K, Gese GV, Kellner N,
Hurt E, Sinning I |
(2023) "Structural
inventory of cotranslational protein folding by the
eukaryotic RAC complex."
Nat.Struct.Mol.Biol., 30,
670-677. doi: 10.1038/s41594-023-00973-1.
|
cryo-EM structure of the ribosome-associated rac
complex on the 80s ribosome - rac-1 conformation .
SNAP output
|
|
7z3o
|
chaperone |
cryo-EM (3.3 Å) |
Kisonaite M, Wild K, Lapouge K, Gese GV, Kellner N,
Hurt E, Sinning I |
(2023) "Structural
inventory of cotranslational protein folding by the
eukaryotic RAC complex."
Nat.Struct.Mol.Biol., 30,
670-677. doi: 10.1038/s41594-023-00973-1.
|
cryo-EM structure of the ribosome-associated rac
complex on the 80s ribosome - rac-2 conformation .
SNAP output
|
|
7z42
|
RNA binding protein |
X-ray (2.418 Å) |
Krischuns T, Isel C, Drncova P, Lukarska M, Pflug A,
Paisant S, Navratil V, Cusack S, Naffakh N |
(2022) "Type B
and type A influenza polymerases have evolved distinct
binding interfaces to recruit the RNA polymerase II
CTD." Plos Pathog., 18,
e1010328. doi: 10.1371/journal.ppat.1010328.
|
Influenza b polymerase with pol ii pser5 ctd peptide
mimic bound in site 2b . SNAP output
|
|
7z43
|
RNA binding protein |
X-ray (3.123 Å) |
Krischuns T, Isel C, Drncova P, Lukarska M, Pflug A,
Paisant S, Navratil V, Cusack S, Naffakh N |
(2022) "Type B
and type A influenza polymerases have evolved distinct
binding interfaces to recruit the RNA polymerase II
CTD." Plos Pathog., 18,
e1010328. doi: 10.1371/journal.ppat.1010328.
|
Influenza b polymerase with pol ii pser5 ctd peptide
mimic bound in site 1b and 2b . SNAP output
|
|
7z4o
|
RNA binding protein |
X-ray (3.412 Å) |
Krischuns T, Isel C, Drncova P, Lukarska M, Pflug A,
Paisant S, Navratil V, Cusack S, Naffakh N |
(2022) "Type B
and type A influenza polymerases have evolved distinct
binding interfaces to recruit the RNA polymerase II
CTD." Plos Pathog., 18,
e1010328. doi: 10.1371/journal.ppat.1010328.
|
Influenza a-h7n9 polymerase core dimer with pol ii
pser5 ctd peptide mimic bound in site 2a . SNAP output
|
|
7z52
|
RNA binding protein |
cryo-EM (3.4 Å) |
Gerlach P, Garland W, Lingaraju M, Salerno-Kochan A,
Bonneau F, Basquin J, Jensen TH, Conti E |
(2022) "Structure
and regulation of the nuclear exosome targeting complex
guides RNA substrates to the exosome."
Mol.Cell, 82, 2505. doi:
10.1016/j.molcel.2022.04.011.
|
Human next dimer - focused reconstruction of the single
mtr4 . SNAP output
|
|
7z55
|
antiviral protein |
X-ray (1.664 Å) |
Molina R, Garcia-Martin R, Lopez-Mendez B, Jensen
ALG, Ciges-Tomas JR, Marchena-Hurtado J, Stella S,
Montoya G |
(2022) "Molecular
basis of cyclic tetra-oligoadenylate processing by
small standalone CRISPR-Cas ring nucleases."
Nucleic Acids Res., 50,
11199-11213. doi: 10.1093/nar/gkac923.
|
Crystal structure of the ring nuclease 0455 from
sulfolobus islandicus (sis0455) in complex with its
substrate . SNAP
output
|
|
7z6a
|
transferase |
X-ray (1.66 Å) |
Rietmeyer L, Li De La Sierra-Gallay I, Schepers G,
Dorchene D, Iannazzo L, Patin D, Touze T, van Tilbeurgh
H, Herdewijn P, Etheve-Quelquejeu M, Fonvielle M |
(2022) "Amino-acyl
tXNA as inhibitors or amino acid donors in peptide
synthesis." Nucleic Acids Res.,
50, 11415-11425. doi: 10.1093/nar/gkac1023.
|
Crystal structure of weissella viridescens femxvv
non-ribosomal amino acid transferase in complex with a
peptidyl-xna conjugate . SNAP output
|
|
7z6k
|
transferase |
X-ray (1.6 Å) |
Rietmeyer L, Li De La Sierra-Gallay I, Schepers G,
Dorchene D, Iannazzo L, Patin D, Touze T, van Tilbeurgh
H, Herdewijn P, Etheve-Quelquejeu M, Fonvielle M |
(2022) "Amino-acyl
tXNA as inhibitors or amino acid donors in peptide
synthesis." Nucleic Acids Res.,
50, 11415-11425. doi: 10.1093/nar/gkac1023.
|
Crystal structure of weissella viridescens femxvv
non-ribosomal amino acid transferase in complex with a
peptidyl-xna conjugate . SNAP output
|
|
7zag
|
translation |
cryo-EM (2.77 Å) |
Kazan R, Bourgeois G, Lazennec-Schurdevin C, Larquet
E, Mechulam Y, Coureux PD, Schmitt E |
(2022) "Role of
aIF5B in archaeal translation initiation."
Nucleic Acids Res., 50,
6532-6548. doi: 10.1093/nar/gkac490.
|
cryo-EM structure of a pyrococcus abyssi 30s bound to
met-initiator trna,mrna, aif1a and the c-terminal
domain of aif5b. . SNAP
output
|
|
7zah
|
translation |
cryo-EM (2.7 Å) |
Kazan R, Bourgeois G, Lazennec-Schurdevin C, Larquet
E, Mechulam Y, Coureux PD, Schmitt E |
(2022) "Role of
aIF5B in archaeal translation initiation."
Nucleic Acids Res., 50,
6532-6548. doi: 10.1093/nar/gkac490.
|
cryo-EM structure of a pyrococcus abyssi 30s bound to
met-initiator trna, mrna, aif1a and aif5b . SNAP output
|
|
7zai
|
translation |
cryo-EM (2.6 Å) |
Kazan R, Bourgeois G, Lazennec-Schurdevin C, Larquet
E, Mechulam Y, Coureux PD, Schmitt E |
(2022) "Role of
aIF5B in archaeal translation initiation."
Nucleic Acids Res., 50,
6532-6548. doi: 10.1093/nar/gkac490.
|
cryo-EM structure of a pyrococcus abyssi 30s bound to
met-initiator trna, mrna and aif1a. . SNAP output
|
|
7zap
|
RNA binding protein |
NMR |
Campagne S, Jutzi D, Malard F, Matoga M, Romane K,
Feldmuller M, Colombo M, Ruepp MD, Allain FH |
(2023) "Molecular
basis of RNA-binding and autoregulation by the
cancer-associated splicing factor RBM39." Nat
Commun, 14, 5366. doi: 10.1038/s41467-023-40254-5.
|
Solution structure of rbm39 rrm1 bound to u1 snrna stem
loop 3 . SNAP output
|
|
7zew
|
transcription |
NMR |
Blatter M, Meylan C, Clery A, Giambruno R, Nikolaev
Y, Heidecker M, Solanki JA, Diaz MO, Gabellini D, Allain
FH |
(2023) "RNA
binding induces an allosteric switch in Cyp33 to
repress MLL1-mediated transcription." Sci
Adv, 9, eadf5330. doi: 10.1126/sciadv.adf5330.
|
Complex cyp33-rrm : aauaaa RNA . SNAP output
|
|
7zex
|
transcription |
NMR |
Blatter M, Meylan C, Clery A, Giambruno R, Nikolaev
Y, Heidecker M, Solanki JA, Diaz MO, Gabellini D, Allain
FH |
(2023) "RNA
binding induces an allosteric switch in Cyp33 to
repress MLL1-mediated transcription." Sci
Adv, 9, eadf5330. doi: 10.1126/sciadv.adf5330.
|
Complex cyp33-rrmdelta alpha : uaaugucg RNA . SNAP output
|
|
7zgp
|
RNA binding protein |
cryo-EM (2.7 Å) |
Rodriguez-Molina JB, O'Reilly FJ, Fagarasan H,
Sheekey E, Maslen S, Skehel JM, Rappsilber J, Passmore
LA |
(2022) "Mpe1
senses the binding of pre-mRNA and controls 3' end
processing by CPF." Mol.Cell,
82, 2490. doi: 10.1016/j.molcel.2022.04.021.
|
Polymerase module of cpf in complex with mpe1 and a
pre-cleaved cyc1 RNA . SNAP output
|
|
7zgr
|
RNA binding protein |
cryo-EM (2.6 Å) |
Rodriguez-Molina JB, O'Reilly FJ, Fagarasan H,
Sheekey E, Maslen S, Skehel JM, Rappsilber J, Passmore
LA |
(2022) "Mpe1
senses the binding of pre-mRNA and controls 3' end
processing by CPF." Mol.Cell,
82, 2490. doi: 10.1016/j.molcel.2022.04.021.
|
Polymerase module of yeast cpf in complex with mpe1,
the ypim of cft2 and the pre-cleaved cyc1 RNA .
SNAP output
|
|
7zgv
|
RNA binding protein |
X-ray (1.48 Å) |
Mayo-Munoz D, Smith LM, Garcia-Doval C, Malone LM,
Harding KR, Jackson SA, Hampton HG, Fagerlund RD, Gumy
LF, Fineran PC |
(2022) "Type III
CRISPR-Cas provides resistance against nucleus-forming
jumbo phages via abortive infection."
Mol.Cell, 82, 4471-4486.e9.
doi: 10.1016/j.molcel.2022.10.028.
|
Serratia nucc bound to ca3 . SNAP output
|
|
7zhg
|
translation |
cryo-EM (2.25 Å) |
Kazan R, Bourgeois G, Lazennec-Schurdevin C, Larquet
E, Mechulam Y, Coureux PD, Schmitt E |
(2022) "Role of
aIF5B in archaeal translation initiation."
Nucleic Acids Res., 50,
6532-6548. doi: 10.1093/nar/gkac490.
|
High-resolution cryo-EM structure of pyrococcus abyssi
30s ribosomal subunit bound to mrna and initiator trna
anticodon stem-loop . SNAP output
|
|
7zhh
|
RNA binding protein |
X-ray (1.6 Å) |
Hollmann NM, Jagtap PKA, Linse JB, Ullmann P, Payr M,
Murciano B, Simon B, Hub JS, Hennig J |
(2023) "Upstream
of N-Ras C-terminal cold shock domains mediate poly(A)
specificity in a novel RNA recognition mode and bind
poly(A) binding protein." Nucleic Acids
Res., 51, 1895-1913. doi:
10.1093/nar/gkac1277.
|
Complex structure of drosophila unr csd789 and a
poly(a) RNA sequence . SNAP output
|
|
7zjw
|
ribosome |
cryo-EM (2.8 Å) |
Hilal T, Killam BY, Grozdanovic M, Dobosz-Bartoszek
M, Loerke J, Burger J, Mielke T, Copeland PR, Simonovic
M, Spahn CMT |
(2022) "Structure
of the mammalian ribosome as it decodes the
selenocysteine UGA codon." Science,
376, 1338-1343. doi: 10.1126/science.abg3875.
|
Rabbit 80s ribosome as it decodes the sec-uga codon .
SNAP output
|
|
7zjx
|
ribosome |
cryo-EM (3.1 Å) |
Hilal T, Killam BY, Grozdanovic M, Dobosz-Bartoszek
M, Loerke J, Burger J, Mielke T, Copeland PR, Simonovic
M, Spahn CMT |
(2022) "Structure
of the mammalian ribosome as it decodes the
selenocysteine UGA codon." Science,
376, 1338-1343. doi: 10.1126/science.abg3875.
|
Rabbit 80s ribosome programmed with secis and sbp2 .
SNAP output
|
|
7zki
|
translation |
cryo-EM (3.6 Å) |
Kazan R, Bourgeois G, Lazennec-Schurdevin C, Larquet
E, Mechulam Y, Coureux PD, Schmitt E |
(2022) "Role of
aIF5B in archaeal translation initiation."
Nucleic Acids Res., 50,
6532-6548. doi: 10.1093/nar/gkac490.
|
cryo-EM structure of aif1a:aif5b:met-trnaimet complex
from a pyrococcus abyssi 30s initiation complex .
SNAP output
|
|
7zlq
|
RNA binding protein |
X-ray (2.8 Å) |
Mboukou A, Rajendra V, Messmer S, Mandl TC, Catala M,
Tisne C, Jantsch MF, Barraud P |
(2024) "Dimerization of ADAR1 modulates
site-specificity of RNA editing." Nat Commun,
15, 10051. doi: 10.1038/s41467-024-53777-2.
|
Crystal structure of adar1-dsrbd3 dimer in complex with
dsrna . SNAP output
|
|
7znj
|
gene regulation |
cryo-EM (2.4 Å) |
Pacheco-Fiallos B, Vorlander MK, Riabov-Bassat D, Fin
L, O'Reilly FJ, Ayala FI, Schellhaas U, Rappsilber J,
Plaschka C |
(2023) "mRNA
recognition and packaging by the human
transcription-export complex." Nature,
616, 828-835. doi: 10.1038/s41586-023-05904-0.
|
Structure of an alyref-exon junction complex hexamer .
SNAP output
|
|
7znk
|
gene regulation |
cryo-EM (3.9 Å) |
Pacheco-Fiallos B, Vorlander MK, Riabov-Bassat D, Fin
L, O'Reilly FJ, Ayala FI, Schellhaas U, Rappsilber J,
Plaschka C |
(2023) "mRNA
recognition and packaging by the human
transcription-export complex." Nature,
616, 828-835. doi: 10.1038/s41586-023-05904-0.
|
Structure of an endogenous human trex complex bound to
mrna . SNAP output
|
|
7zod
|
ribosome |
cryo-EM (2.56 Å) |
Ahn M, Wlodarski T, Mitropoulou A, Chan SHS, Sidhu H,
Plessa E, Becker TA, Budisa N, Waudby CA, Beckmann R,
Cassaignau AME, Cabrita LD, Christodoulou J |
(2022) "Modulating
co-translational protein folding by rational design and
ribosome engineering." Nat Commun,
13, 4243. doi: 10.1038/s41467-022-31906-z.
|
70s e. coli ribosome with an extended ul23 loop from
candidatus marinimicrobia . SNAP output
|
|
7zol
|
antiviral protein |
cryo-EM (3.03 Å) |
Ekundayo B, Torre D, Beckert B, Nazarov S, Myasnikov
A, Stahlberg H, Ni D |
(2023) "Structural
insights into the regulation of Cas7-11 by
TPR-CHAT." Nat.Struct.Mol.Biol.,
30, 135-139. doi: 10.1038/s41594-022-00894-5.
|
cryo-EM structure of a crispr effector in complex with
regulator . SNAP
output
|
|
7zoq
|
antiviral protein |
cryo-EM (3.2 Å) |
Ekundayo B, Torre D, Beckert B, Nazarov S, Myasnikov
A, Stahlberg H, Ni D |
(2023) "Structural
insights into the regulation of Cas7-11 by
TPR-CHAT." Nat.Struct.Mol.Biol.,
30, 135-139. doi: 10.1038/s41594-022-00894-5.
|
cryo-EM structure of a crispr effector in complex with
a caspase regulator . SNAP output
|
|
7zp8
|
ribosome |
cryo-EM (2.2 Å) |
Ahn M, Wlodarski T, Mitropoulou A, Chan SHS, Sidhu H,
Plessa E, Becker TA, Budisa N, Waudby CA, Beckmann R,
Cassaignau AME, Cabrita LD, Christodoulou J |
(2022) "Modulating
co-translational protein folding by rational design and
ribosome engineering." Nat Commun,
13, 4243. doi: 10.1038/s41467-022-31906-z.
|
70s e. coli ribosome with a stalled filamin domain 5
nascent chain . SNAP
output
|
|
7zpi
|
RNA binding protein |
cryo-EM (5.91 Å) |
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek
K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F,
Jenickova I, Prochazkova M, Prochazka J, Pinkas M,
Novacek J, Joseph DF, Sedlacek R, Bernecky C, O'Carroll
D, Stefl R, Svoboda P |
(2022) "Structural
and functional basis of mammalian microRNA biogenesis
by Dicer." Mol.Cell, 82,
4064-4079.e13. doi: 10.1016/j.molcel.2022.10.010.
|
Mammalian dicer in the "dicing state" with pre-mir-15a
substrate . SNAP
output
|
|
7zpj
|
RNA binding protein |
cryo-EM (3.81 Å) |
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek
K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F,
Jenickova I, Prochazkova M, Prochazka J, Pinkas M,
Novacek J, Joseph DF, Sedlacek R, Bernecky C, O'Carroll
D, Stefl R, Svoboda P |
(2022) "Structural
and functional basis of mammalian microRNA biogenesis
by Dicer." Mol.Cell, 82,
4064-4079.e13. doi: 10.1016/j.molcel.2022.10.010.
|
Mammalian dicer in the "pre-dicing state" with
pre-mir-15a substrate and tarbp2 subunit . SNAP output
|
|
7zpk
|
RNA binding protein |
cryo-EM (3.81 Å) |
Zapletal D, Taborska E, Pasulka J, Malik R, Kubicek
K, Zanova M, Much C, Sebesta M, Buccheri V, Horvat F,
Jenickova I, Prochazkova M, Prochazka J, Pinkas M,
Novacek J, Joseph DF, Sedlacek R, Bernecky C, O'Carroll
D, Stefl R, Svoboda P |
(2022) "Structural
and functional basis of mammalian microRNA biogenesis
by Dicer." Mol.Cell, 82,
4064-4079.e13. doi: 10.1016/j.molcel.2022.10.010.
|
Mammalian dicer in the "pre-dicing state" with
pre-mir-15a substrate and tarbp2 subunit . SNAP output
|
|
7zpl
|
viral protein |
cryo-EM (3.12 Å) |
Kouba T, Dubankova A, Drncova P, Donati E, Vidossich
P, Speranzini V, Pflug A, Huchting J, Meier C, De Vivo M,
Cusack S |
(2023) "Direct
observation of backtracking by influenza A and B
polymerases upon consecutive incorporation of the
nucleoside analog T1106." Cell Rep,
42, 111901. doi: 10.1016/j.celrep.2022.111901.
|
Symmetric dimer of influenza a-h7n9 polymerase bound to
5' vrna hook . SNAP
output
|
|
7zpq
|
ribosome |
cryo-EM (3.47 Å) |
Best K, Ikeuchi K, Kater L, Best D, Musial J, Matsuo
Y, Berninghausen O, Becker T, Inada T, Beckmann R |
(2023) "Structural
basis for clearing of ribosome collisions by the RQT
complex." Nat Commun, 14,
921. doi: 10.1038/s41467-023-36230-8.
|
Structure of the rqt-bound 80s ribosome from s.
cerevisiae (c1) . SNAP
output
|
|
7zq5
|
ribosome |
cryo-EM (2.7 Å) |
Ahn M, Wlodarski T, Mitropoulou A, Chan SHS, Sidhu H,
Plessa E, Becker TA, Budisa N, Waudby CA, Beckmann R,
Cassaignau AME, Cabrita LD, Christodoulou J |
(2022) "Modulating
co-translational protein folding by rational design and
ribosome engineering." Nat Commun,
13, 4243. doi: 10.1038/s41467-022-31906-z.
|
70s e. coli ribosome with truncated ul23 and ul24 loops
. SNAP output
|
|
7zq6
|
ribosome |
cryo-EM (2.75 Å) |
Ahn M, Wlodarski T, Mitropoulou A, Chan SHS, Sidhu H,
Plessa E, Becker TA, Budisa N, Waudby CA, Beckmann R,
Cassaignau AME, Cabrita LD, Christodoulou J |
(2022) "Modulating
co-translational protein folding by rational design and
ribosome engineering." Nat Commun,
13, 4243. doi: 10.1038/s41467-022-31906-z.
|
70s e. coli ribosome with truncated ul23 and ul24 loops
and a stalled filamin domain 5 nascent chain . SNAP output
|
|
7zrs
|
ribosome |
cryo-EM (4.8 Å) |
Best K, Ikeuchi K, Kater L, Best D, Musial J, Matsuo
Y, Berninghausen O, Becker T, Inada T, Beckmann R |
(2023) "Structural
basis for clearing of ribosome collisions by the RQT
complex." Nat Commun, 14,
921. doi: 10.1038/s41467-023-36230-8.
|
Structure of the rqt-bound 80s ribosome from s.
cerevisiae (c2) - composite map . SNAP output
|
|
7zrz
|
RNA binding protein |
cryo-EM (3.09 Å) |
Sekulovski S, Susac L, Stelzl LS, Tampe R, Trowitzsch
S |
(2023) "Structural
basis of substrate recognition by human tRNA splicing
endonuclease TSEN." Nat.Struct.Mol.Biol.,
30, 834-840. doi: 10.1038/s41594-023-00992-y.
|
Structure of the human trna splicing endonuclease
defines substrate recognition . SNAP output
|
|
7zs5
|
ribosome |
cryo-EM (3.2 Å) |
Best K, Ikeuchi K, Kater L, Best D, Musial J, Matsuo
Y, Berninghausen O, Becker T, Inada T, Beckmann R |
(2023) "Structural
basis for clearing of ribosome collisions by the RQT
complex." Nat Commun, 14,
921. doi: 10.1038/s41467-023-36230-8.
|
Structure of 60s ribosomal subunit from s. cerevisiae
with eif6 and trna . SNAP output
|
|
7zta
|
ribosome |
cryo-EM (2.7 Å) |
Leroy EC, Perry TN, Renault TT, Innis CA |
(2023) "Tetracenomycin
X sequesters peptidyl-tRNA during translation of QK
motifs." Nat.Chem.Biol.,
19, 1091-1096. doi: 10.1038/s41589-023-01343-0.
|
Structure of an escherichia coli 70s ribosome stalled
by tetracenomycin x during translation of an maaapqk(c)
peptide . SNAP
output
|
|
7zuw
|
ribosome |
cryo-EM (4.3 Å) |
Best K, Ikeuchi K, Kater L, Best D, Musial J, Matsuo
Y, Berninghausen O, Becker T, Inada T, Beckmann R |
(2023) "Structural
basis for clearing of ribosome collisions by the RQT
complex." Nat Commun, 14,
921. doi: 10.1038/s41467-023-36230-8.
|
Structure of rqt (c1) bound to the stalled ribosome in
a disome unit from s. cerevisiae . SNAP output
|
|
7zux
|
ribosome |
cryo-EM (2.5 Å) |
Best K, Ikeuchi K, Kater L, Best D, Musial J, Matsuo
Y, Berninghausen O, Becker T, Inada T, Beckmann R |
(2023) "Structural
basis for clearing of ribosome collisions by the RQT
complex." Nat Commun, 14,
921. doi: 10.1038/s41467-023-36230-8.
|
Collided ribosome in a disome unit from s. cerevisiae .
SNAP output
|
|
7zw0
|
ribosome |
cryo-EM (2.4 Å) |
Li S, Ikeuchi K, Kato M, Buschauer R, Sugiyama T,
Adachi S, Kusano H, Natsume T, Berninghausen O, Matsuo Y,
Becker T, Beckmann R, Inada T |
(2022) "Sensing
of individual stalled 80S ribosomes by Fap1 for
nonfunctional rRNA turnover." Mol.Cell,
82, 3424-3437.e8. doi: 10.1016/j.molcel.2022.08.018.
|
Fap-80s complex - rotated state . SNAP output
|
|
8a22
|
ribosome |
cryo-EM (2.91 Å) |
Tobiasson V, Berzina I, Amunts A |
(2022) "Structure
of a mitochondrial ribosome with fragmented rRNA in
complex with membrane-targeting elements." Nat
Commun, 13, 6132. doi: 10.1038/s41467-022-33582-5.
|
Structure of the mitochondrial ribosome from
polytomella magna . SNAP
output
|
|
8a3d
|
translation |
cryo-EM (1.67 Å) |
Faille A, Dent KC, Pellegrino S, Jaako P, Warren
AJ |
(2023) "The
chemical landscape of the human ribosome at 1.67
angstrom resolution." Biorxiv. doi:
10.1101/2023.02.28.530191.
|
Human mature large subunit of the ribosome with eif6
and homoharringtonine bound . SNAP output
|
|
8a3l
|
ribosome |
cryo-EM (3.42 Å) |
D'Urso G, Chat S, Gillet R, Giudice E |
(2023) "Structural
insights into the binding of bS1 to the ribosome."
Nucleic Acids Res., 51,
3410-3419. doi: 10.1093/nar/gkad126.
|
Structural insights into the binding of bs1 to the
ribosome . SNAP
output
|
|
8a57
|
ribosome |
cryo-EM (2.3 Å) |
Koller TO, Turnbull KJ, Vaitkevicius K,
Crowe-McAuliffe C, Roghanian M, Bulvas O, Nakamoto JA,
Kurata T, Julius C, Atkinson GC, Johansson J, Hauryliuk
V, Wilson DN |
(2022) "Structural
basis for HflXr-mediated antibiotic resistance in
Listeria monocytogenes." Nucleic Acids
Res., 50, 11285-11300. doi:
10.1093/nar/gkac934.
|
cryo-EM structure of hflxr bound to the listeria
monocytogenes 50s ribosomal subunit. . SNAP output
|
|
8a5i
|
ribosome |
cryo-EM (2.3 Å) |
Koller TO, Turnbull KJ, Vaitkevicius K,
Crowe-McAuliffe C, Roghanian M, Bulvas O, Nakamoto JA,
Kurata T, Julius C, Atkinson GC, Johansson J, Hauryliuk
V, Wilson DN |
(2022) "Structural
basis for HflXr-mediated antibiotic resistance in
Listeria monocytogenes." Nucleic Acids
Res., 50, 11285-11300. doi:
10.1093/nar/gkac934.
|
cryo-EM structure of lincomycin bound to the listeria
monocytogenes 50s ribosomal subunit. . SNAP output
|
|
8a63
|
ribosome |
cryo-EM (3.1 Å) |
Koller TO, Turnbull KJ, Vaitkevicius K,
Crowe-McAuliffe C, Roghanian M, Bulvas O, Nakamoto JA,
Kurata T, Julius C, Atkinson GC, Johansson J, Hauryliuk
V, Wilson DN |
(2022) "Structural
basis for HflXr-mediated antibiotic resistance in
Listeria monocytogenes." Nucleic Acids
Res., 50, 11285-11300. doi:
10.1093/nar/gkac934.
|
cryo-EM structure of listeria monocytogenes 50s
ribosomal subunit. . SNAP output
|
|
8a98
|
ribosome |
cryo-EM (2.46 Å) |
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H,
Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka
M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E,
Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF,
Yonath A, Michaeli S |
(2024) "Structural
and mechanistic insights into the function of
Leishmania ribosome lacking a single pseudouridine
modification." Cell Rep,
43, 114203. doi: 10.1016/j.celrep.2024.114203.
|
cryo-EM structure of leishmania major 80s ribosome :
snorna mutant . SNAP
output
|
|
8aaf
|
translation |
cryo-EM (2.5 Å) |
Tesina P, Ebine S, Buschauer R, Thoms M, Matsuo Y,
Inada T, Beckmann R |
(2023) "Molecular
basis of eIF5A-dependent CAT tailing in eukaryotic
ribosome-associated quality control."
Mol.Cell, 83, 607-621.e4.
doi: 10.1016/j.molcel.2023.01.020.
|
Yeast rqc complex in state g . SNAP output
|
|
8acb
|
virus like particle |
cryo-EM (2.6 Å) |
Chase O, Javed A, Byrne MJ, Thuenemann EC,
Lomonossoff GP, Ranson NA, Lopez-Moya JJ |
(2023) "CryoEM
and stability analysis of virus-like particles of
potyvirus and ipomovirus infecting a common host."
Commun Biol, 6, 433. doi:
10.1038/s42003-023-04799-x.
|
Cryoem structure of sweet potato feathery mottle virus
vlp . SNAP output
|
|
8acc
|
virus like particle |
cryo-EM (2.9 Å) |
Chase O, Javed A, Byrne MJ, Thuenemann EC,
Lomonossoff GP, Ranson NA, Lopez-Moya JJ |
(2023) "CryoEM
and stability analysis of virus-like particles of
potyvirus and ipomovirus infecting a common host."
Commun Biol, 6, 433. doi:
10.1038/s42003-023-04799-x.
|
Cryoem structure of sweet potato mild mottle virus vlp
. SNAP output
|
|
8af0
|
RNA binding protein |
X-ray (2.43 Å) |
Sievers K, Ficner R |
(2022) "Structure
of angiogenin dimer bound to double-stranded RNA."
Acta Crystallogr.,Sect.F, 78,
330-337. doi: 10.1107/S2053230X22008317.
|
Crystal structure of human angiogenin and RNA duplex .
SNAP output
|
|
8agt
|
translation |
cryo-EM (2.6 Å) |
Tesina P, Ebine S, Buschauer R, Thoms M, Matsuo Y,
Inada T, Beckmann R |
(2023) "Molecular
basis of eIF5A-dependent CAT tailing in eukaryotic
ribosome-associated quality control."
Mol.Cell, 83, 607-621.e4.
doi: 10.1016/j.molcel.2023.01.020.
|
Yeast rqc complex in state f . SNAP output
|
|
8agu
|
translation |
cryo-EM (2.7 Å) |
Tesina P, Ebine S, Buschauer R, Thoms M, Matsuo Y,
Inada T, Beckmann R |
(2023) "Molecular
basis of eIF5A-dependent CAT tailing in eukaryotic
ribosome-associated quality control."
Mol.Cell, 83, 607-621.e4.
doi: 10.1016/j.molcel.2023.01.020.
|
Yeast rqc complex in state e . SNAP output
|
|
8agv
|
translation |
cryo-EM (2.6 Å) |
Tesina P, Ebine S, Buschauer R, Thoms M, Matsuo Y,
Inada T, Beckmann R |
(2023) "Molecular
basis of eIF5A-dependent CAT tailing in eukaryotic
ribosome-associated quality control."
Mol.Cell, 83, 607-621.e4.
doi: 10.1016/j.molcel.2023.01.020.
|
Yeast rqc complex in state h . SNAP output
|
|
8agw
|
translation |
cryo-EM (2.6 Å) |
Tesina P, Ebine S, Buschauer R, Thoms M, Matsuo Y,
Inada T, Beckmann R |
(2023) "Molecular
basis of eIF5A-dependent CAT tailing in eukaryotic
ribosome-associated quality control."
Mol.Cell, 83, 607-621.e4.
doi: 10.1016/j.molcel.2023.01.020.
|
Yeast rqc complex in state d . SNAP output
|
|
8agx
|
translation |
cryo-EM (2.4 Å) |
Tesina P, Ebine S, Buschauer R, Thoms M, Matsuo Y,
Inada T, Beckmann R |
(2023) "Molecular
basis of eIF5A-dependent CAT tailing in eukaryotic
ribosome-associated quality control."
Mol.Cell, 83, 607-621.e4.
doi: 10.1016/j.molcel.2023.01.020.
|
Yeast rqc complex in state with the ring domain of ltn1
in the in position . SNAP output
|
|
8agz
|
translation |
cryo-EM (2.6 Å) |
Tesina P, Ebine S, Buschauer R, Thoms M, Matsuo Y,
Inada T, Beckmann R |
(2023) "Molecular
basis of eIF5A-dependent CAT tailing in eukaryotic
ribosome-associated quality control."
Mol.Cell, 83, 607-621.e4.
doi: 10.1016/j.molcel.2023.01.020.
|
Yeast rqc complex in state with the ring domain of ltn1
in the out position . SNAP output
|
|
8akn
|
ribosome |
cryo-EM (2.3 Å) |
Koller TO, Morici M, Berger M, Safdari HA, Lele DS,
Beckert B, Kaur KJ, Wilson DN |
(2023) "Structural
basis for translation inhibition by the glycosylated
drosocin peptide." Nat.Chem.Biol.,
19, 1072-1081. doi: 10.1038/s41589-023-01293-7.
|
cryo-EM structure of the proline-rich antimicrobial
peptide drosocin bound to the terminating ribosome .
SNAP output
|
|
8am9
|
ribosome |
cryo-EM (2.8 Å) |
Koller TO, Morici M, Berger M, Safdari HA, Lele DS,
Beckert B, Kaur KJ, Wilson DN |
(2023) "Structural
basis for translation inhibition by the glycosylated
drosocin peptide." Nat.Chem.Biol.,
19, 1072-1081. doi: 10.1038/s41589-023-01293-7.
|
cryo-EM structure of the proline-rich antimicrobial
peptide drosocin bound to the elongating ribosome .
SNAP output
|
|
8ana
|
ribosome |
cryo-EM (2.1 Å) |
Koller TO, Morici M, Berger M, Safdari HA, Lele DS,
Beckert B, Kaur KJ, Wilson DN |
(2023) "Structural
basis for translation inhibition by the glycosylated
drosocin peptide." Nat.Chem.Biol.,
19, 1072-1081. doi: 10.1038/s41589-023-01293-7.
|
cryo-EM structure of the proline-rich antimicrobial
peptide drosocin bound to the 50s ribosomal subunit .
SNAP output
|
|
8ane
|
immune system |
cryo-EM (3.2 Å) |
Shangguan Q, Graham S, Sundaramoorthy R, White
MF |
(2022) "Structure
and mechanism of the type I-G CRISPR effector."
Nucleic Acids Res., 50,
11214-11228. doi: 10.1093/nar/gkac925.
|
Structure of the type i-g crispr effector . SNAP output
|
|
8any
|
ribosome |
cryo-EM (2.85 Å) |
Singh V, Moran JC, Itoh Y, Soto IC, Fontanesi F,
Couvillion M, Huynen MA, Churchman LS, Barrientos A,
Amunts A |
(2024) "Structural
basis of LRPPRC-SLIRP-dependent translation by the
mitoribosome." Nat.Struct.Mol.Biol. doi:
10.1038/s41594-024-01365-9.
|
Human mitochondrial ribosome in complex with lrpprc,
slirp, a-site, p-site, e-site trnas and mrna . SNAP output
|
|
8ap4
|
translation |
cryo-EM (3.0 Å) |
Safdari HA, Kasvandik S, Polte C, Ignatova Z, Tenson
T, Wilson DN |
(2022) "Structure
of Escherichia coli heat shock protein Hsp15 in complex
with the ribosomal 50S subunit bearing
peptidyl-tRNA." Nucleic Acids Res.,
50, 12515-12526. doi: 10.1093/nar/gkac1035.
|
Structure of escherischia coli heat shock protein hsp15
in complex with ribosomal 50s subunits bearing
peptidyl-trna . SNAP
output
|
|
8apn
|
ribosome |
cryo-EM (3.1 Å) |
Tobiasson V, Berzina I, Amunts A |
(2022) "Structure
of a mitochondrial ribosome with fragmented rRNA in
complex with membrane-targeting elements." Nat
Commun, 13, 6132. doi: 10.1038/s41467-022-33582-5.
|
Structure of the mitochondrial ribosome from
polytomella magna with trna bound to the p site .
SNAP output
|
|
8apo
|
ribosome |
cryo-EM (3.2 Å) |
Tobiasson V, Berzina I, Amunts A |
(2022) "Structure
of a mitochondrial ribosome with fragmented rRNA in
complex with membrane-targeting elements." Nat
Commun, 13, 6132. doi: 10.1038/s41467-022-33582-5.
|
Structure of the mitochondrial ribosome from
polytomella magna with trnas bound to the a and p sites
. SNAP output
|
|
8as6
|
viral protein |
cryo-EM (3.4 Å) |
Williams HM, Thorkelsson SR, Vogel D, Milewski M,
Busch C, Cusack S, Grunewald K, Quemin ERJ, Rosenthal
M |
(2023) "Structural
insights into viral genome replication by the severe
fever with thrombocytopenia syndrome virus L
protein." Nucleic Acids Res.,
51, 1424-1442. doi: 10.1093/nar/gkac1249.
|
Structure of the sftsv l protein bound to 5' crna hook
[5' hook] . SNAP
output
|
|
8as7
|
viral protein |
cryo-EM (2.6 Å) |
Williams HM, Thorkelsson SR, Vogel D, Milewski M,
Busch C, Cusack S, Grunewald K, Quemin ERJ, Rosenthal
M |
(2023) "Structural
insights into viral genome replication by the severe
fever with thrombocytopenia syndrome virus L
protein." Nucleic Acids Res.,
51, 1424-1442. doi: 10.1093/nar/gkac1249.
|
Structure of the sftsv l protein stalled at early
elongation [early-elongation] . SNAP output
|
|
8asb
|
viral protein |
cryo-EM (3.6 Å) |
Williams HM, Thorkelsson SR, Vogel D, Milewski M,
Busch C, Cusack S, Grunewald K, Quemin ERJ, Rosenthal
M |
(2023) "Structural
insights into viral genome replication by the severe
fever with thrombocytopenia syndrome virus L
protein." Nucleic Acids Res.,
51, 1424-1442. doi: 10.1093/nar/gkac1249.
|
Structure of the sftsv l protein stalled at early
elongation with the endonuclease domain in a raised
conformation [early-elongation-endo] . SNAP output
|
|
8asd
|
viral protein |
cryo-EM (2.6 Å) |
Williams HM, Thorkelsson SR, Vogel D, Milewski M,
Busch C, Cusack S, Grunewald K, Quemin ERJ, Rosenthal
M |
(2023) "Structural
insights into viral genome replication by the severe
fever with thrombocytopenia syndrome virus L
protein." Nucleic Acids Res.,
51, 1424-1442. doi: 10.1093/nar/gkac1249.
|
Structure of the sftsv l protein stalled at late
elongation [late-elongation] . SNAP output
|
|
8asg
|
viral protein |
cryo-EM (3.2 Å) |
Williams HM, Thorkelsson SR, Vogel D, Milewski M,
Busch C, Cusack S, Grunewald K, Quemin ERJ, Rosenthal
M |
(2023) "Structural
insights into viral genome replication by the severe
fever with thrombocytopenia syndrome virus L
protein." Nucleic Acids Res.,
51, 1424-1442. doi: 10.1093/nar/gkac1249.
|
Structure of the sftsv l protein bound in a resting
state [resting] . SNAP
output
|
|
8asw
|
translation |
cryo-EM (3.96 Å) |
Jaciuk M, Scherf D, Kaszuba K, Gaik M, Rau A,
Koscielniak A, Krutyholowa R, Rawski M, Indyka P,
Graziadei A, Chramiec-Glabik A, Biela A, Dobosz D, Lin
TY, Abbassi NE, Hammermeister A, Rappsilber J, Kosinski
J, Schaffrath R, Glatt S |
(2023) "Cryo-EM
structure of the fully assembled Elongator
complex." Nucleic Acids Res.,
51, 2011-2032. doi: 10.1093/nar/gkac1232.
|
cryo-EM structure of yeast elp123 in complex with
alanine trna . SNAP
output
|
|
8auv
|
ribosome |
cryo-EM (2.38 Å) |
Smirnova J, Loerke J, Kleinau G, Schmidt A, Burger J,
Meyer EH, Mielke T, Scheerer P, Bock R, Spahn CMT,
Zoschke R |
(2023) "Structure
of the actively translating plant 80S ribosome at 2.2
angstrom resolution." Nat.Plants,
9, 987-1000. doi: 10.1038/s41477-023-01407-y.
|
cryo-EM structure of the plant 40s subunit . SNAP output
|
|
8aw3
|
RNA binding protein |
cryo-EM (3.6 Å) |
Dolce LG, Zimmer AA, Tengo L, Weis F, Rubio MAT,
Alfonzo JD, Kowalinski E |
(2022) "Structural
basis for sequence-independent substrate selection by
eukaryotic wobble base tRNA deaminase ADAT2/3."
Nat Commun, 13, 6737. doi:
10.1038/s41467-022-34441-z.
|
cryo-EM structure of the tb adat2-3 deaminase in
complex with trna . SNAP
output
|
|
8axb
|
DNA binding protein |
cryo-EM (2.87 Å) |
Tenjo-Castano F, Sofos N, Stutzke LS, Temperini P,
Fuglsang A, Pape T, Mesa P, Montoya G |
(2024) "Conformational
landscape of the type V-K CRISPR-associated transposon
integration assembly." Mol.Cell,
84, 2353-2367.e5. doi: 10.1016/j.molcel.2024.05.005.
|
cryo-EM structure of cas12k-sgrna binary complex (type
v-k crispr-associated transposon) . SNAP output
|
|
8axf
|
viral protein |
X-ray (2.54 Å) |
Izhaki-Tavor LS, Yechezkel IG, Alter J, Dessau M |
(2023) "RNA
Encapsulation Mode and Evolutionary Insights from the
Crystal Structure of Emaravirus Nucleoprotein."
Microbiol Spectr, 11,
e0501822. doi: 10.1128/spectrum.05018-22.
|
Crystal structure of fmv n bound to 42-mer ssrna .
SNAP output
|
|
8aye
|
ribosome |
cryo-EM (1.96 Å) |
Parajuli NP, Emmerich A, Mandava CS, Pavlov MY,
Sanyal S |
(2023) "Antibiotic
thermorubin tethers ribosomal subunits and impedes
A-site interactions to perturb protein synthesis in
bacteria." Nat Commun,
14, 918. doi: 10.1038/s41467-023-36528-7.
|
E. coli 70s ribosome bound to thermorubin and fmet-trna
. SNAP output
|
|
8azw
|
ribosome |
cryo-EM (2.14 Å) |
Smirnova J, Loerke J, Kleinau G, Schmidt A, Burger J,
Meyer EH, Mielke T, Scheerer P, Bock R, Spahn CMT,
Zoschke R |
(2023) "Structure
of the actively translating plant 80S ribosome at 2.2
angstrom resolution." Nat.Plants,
9, 987-1000. doi: 10.1038/s41477-023-01407-y.
|
cryo-EM structure of the plant 60s subunit . SNAP output
|
|
8b0i
|
RNA binding protein |
cryo-EM (4.28 Å) |
Islam MS, Hardwick SW, Quell L, Durica-Mitic S,
Chirgadze DY, Gorke B, Luisi BF |
(2023) "Structure
of a bacterial ribonucleoprotein complex central to the
control of cell envelope biogenesis." Embo
J., 42, e112574. doi: 10.15252/embj.2022112574.
|
Cryoem structure of bacterial rapz.glmz complex central
to the control of cell envelope biogenesis . SNAP output
|
|
8b0j
|
RNA binding protein |
cryo-EM (3.99 Å) |
Islam MS, Hardwick SW, Quell L, Durica-Mitic S,
Chirgadze DY, Gorke B, Luisi BF |
(2023) "Structure
of a bacterial ribonucleoprotein complex central to the
control of cell envelope biogenesis." Embo
J., 42, e112574. doi: 10.15252/embj.2022112574.
|
Cryoem structure of bacterial rnasee.rapz.glmz complex
central to the control of cell envelope biogenesis .
SNAP output
|
|
8b0r
|
hydrolase |
X-ray (2.2 Å) |
Rouillon C, Schneberger N, Chi H, Blumenstock K, Da
Vela S, Ackermann K, Moecking J, Peter MF, Boenigk W,
Seifert R, Bode BE, Schmid-Burgk JL, Svergun D, Geyer M,
White MF, Hagelueken G |
(2023) "Antiviral
signalling by a cyclic nucleotide activated CRISPR
protease." Nature, 614,
168-174. doi: 10.1038/s41586-022-05571-7.
|
Structure of the calpl-ca4 complex . SNAP output
|
|
8b0x
|
ribosome |
cryo-EM (1.55 Å) |
Fromm SA, O'Connor KM, Purdy M, Bhatt PR, Loughran G,
Atkins JF, Jomaa A, Mattei S |
(2023) "The
translating bacterial ribosome at 1.55 angstrom
resolution generated by cryo-EM imaging services."
Nat Commun, 14, 1095. doi:
10.1038/s41467-023-36742-3.
|
Translating 70s ribosome in the unrotated state (p and
e, trnas) . SNAP
output
|
|
8b2l
|
ribosome |
cryo-EM (2.2 Å) |
Smirnova J, Loerke J, Kleinau G, Schmidt A, Burger J,
Meyer EH, Mielke T, Scheerer P, Bock R, Spahn CMT,
Zoschke R |
(2023) "Structure
of the actively translating plant 80S ribosome at 2.2
angstrom resolution." Nat.Plants,
9, 987-1000. doi: 10.1038/s41477-023-01407-y.
|
cryo-EM structure of the plant 80s ribosome . SNAP output
|
|
8b5l
|
membrane protein |
cryo-EM (2.86 Å) |
Pauwels E, Shewakramani NR, De Wijngaert B, Camps A,
Provinciael B, Stroobants J, Kalies KU, Hartmann E, Maes
P, Vermeire K, Das K |
(2023) "Structural
insights into TRAP association with ribosome-Sec61
complex and translocon inhibition by a CADA
derivative." Sci Adv, 9,
eadf0797. doi: 10.1126/sciadv.adf0797.
|
cryo-EM structure of ribosome-sec61-trap (translocon
associated protein) translocon complex . SNAP output
|
|
8b6c
|
membrane protein |
cryo-EM (2.79 Å) |
Pauwels E, Shewakramani NR, De Wijngaert B, Camps A,
Provinciael B, Stroobants J, Kalies KU, Hartmann E, Maes
P, Vermeire K, Das K |
(2023) "Structural
insights into TRAP association with ribosome-Sec61
complex and translocon inhibition by a CADA
derivative." Sci Adv, 9,
eadf0797. doi: 10.1126/sciadv.adf0797.
|
cryo-EM structure of ribosome-sec61 in complex with
cyclotriazadisulfonamide derivative ck147 . SNAP output
|
|
8b6z
|
ribosome |
cryo-EM (2.9 Å) |
Gemmer M, Chaillet ML, van Loenhout J, Cuevas Arenas
R, Vismpas D, Grollers-Mulderij M, Koh FA, Albanese P,
Scheltema RA, Howes SC, Kotecha A, Fedry J, Forster
F |
(2023) "Visualization
of translation and protein biogenesis at the ER
membrane." Nature, 614,
160-167. doi: 10.1038/s41586-022-05638-5.
|
Cryoem structure of extended eef1a bound to the
ribosome in the classical pre state . SNAP output
|
|
8b7y
|
ribosome |
cryo-EM (3.0 Å) |
Koller TO, Scheid U, Kosel T, Herrmann J, Krug D,
Boshoff HIM, Beckert B, Evans JC, Schlemmer J, Sloan B,
Weiner DM, Via LE, Moosa A, Ioerger TR, Graf M, Zinshteyn
B, Abdelshahid M, Nguyen F, Arenz S, Gille F, Siebke M,
Seedorf T, Plettenburg O, Green R, Warnke AL, Ullrich J,
Warrass R, Barry 3rd CE, Warner DF, Mizrahi V, Kirschning
A, Wilson DN, Muller R |
(2023) "The
Myxobacterial Antibiotic Myxovalargin: Biosynthesis,
Structural Revision, Total Synthesis, and Molecular
Characterization of Ribosomal Inhibition."
J.Am.Chem.Soc., 145, 851-863.
doi: 10.1021/jacs.2c08816.
|
cryo-EM structure of the e.coli 70s ribosome in complex
with the antibiotic myxovalargin b. . SNAP output
|
|
8b9g
|
RNA binding protein |
cryo-EM (2.86 Å) |
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K,
Beck M, Becker PB, Hennig J |
(2023) "Structural
basis of RNA-induced autoregulation of the DExH-type
RNA helicase maleless." Mol.Cell,
83, 4318-4333.e10. doi: 10.1016/j.molcel.2023.10.026.
|
cryo-EM structure of mle in complex with adp:alf4 and
u10 RNA . SNAP
output
|
|
8b9i
|
RNA binding protein |
cryo-EM (2.95 Å) |
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K,
Beck M, Becker PB, Hennig J |
(2023) "Structural
basis of RNA-induced autoregulation of the DExH-type
RNA helicase maleless." Mol.Cell,
83, 4318-4333.e10. doi: 10.1016/j.molcel.2023.10.026.
|
cryo-EM structure of mle in complex with adp:alf4 and
uuc RNA . SNAP
output
|
|
8b9k
|
RNA binding protein |
cryo-EM (4.04 Å) |
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K,
Beck M, Becker PB, Hennig J |
(2023) "Structural
basis of RNA-induced autoregulation of the DExH-type
RNA helicase maleless." Mol.Cell,
83, 4318-4333.e10. doi: 10.1016/j.molcel.2023.10.026.
|
cryo-EM structure of mle in complex with adp:alf4 and
sl7moduuc RNA . SNAP
output
|
|
8bao
|
DNA binding protein |
X-ray (2.06 Å) |
Zabrady M, Zabrady K, Li AWH, Doherty AJ |
(2023) "Reverse
transcriptases prime DNA synthesis." Nucleic
Acids Res., 51, 7125-7142. doi:
10.1093/nar/gkad478.
|
Dysgonamonadaceae bacterium crispr ancillary nuclease 2
. SNAP output
|
|
8bdr
|
viral protein |
cryo-EM (2.7 Å) |
Kouba T, Dubankova A, Drncova P, Donati E, Vidossich
P, Speranzini V, Pflug A, Huchting J, Meier C, De Vivo M,
Cusack S |
(2023) "Direct
observation of backtracking by influenza A and B
polymerases upon consecutive incorporation of the
nucleoside analog T1106." Cell Rep,
42, 111901. doi: 10.1016/j.celrep.2022.111901.
|
Early transcription elongation state of influenza b-mem
polymerase backtracked due to double incoproation of
nucleotide analogue t1106 and with singly incoporated
t1106 at the u +1 position . SNAP output
|
|
8be0
|
viral protein |
cryo-EM (2.34 Å) |
Kouba T, Dubankova A, Drncova P, Donati E, Vidossich
P, Speranzini V, Pflug A, Huchting J, Meier C, De Vivo M,
Cusack S |
(2023) "Direct
observation of backtracking by influenza A and B
polymerases upon consecutive incorporation of the
nucleoside analog T1106." Cell Rep,
42, 111901. doi: 10.1016/j.celrep.2022.111901.
|
Early transcription elongation state of influenza b-mem
polymerase backtracked due to double incoproation of
nucleotide analogue t1106 and with singly incoporated
t1106 at the c +1 position . SNAP output
|
|
8bek
|
viral protein |
cryo-EM (2.86 Å) |
Kouba T, Dubankova A, Drncova P, Donati E, Vidossich
P, Speranzini V, Pflug A, Huchting J, Meier C, De Vivo M,
Cusack S |
(2023) "Direct
observation of backtracking by influenza A and B
polymerases upon consecutive incorporation of the
nucleoside analog T1106." Cell Rep,
42, 111901. doi: 10.1016/j.celrep.2022.111901.
|
Early transcription elongation state of influenza
a-h7n9 backtracked polymerase with singly incoporated
t1106 at the u +1 position . SNAP output
|
|
8bf5
|
viral protein |
cryo-EM (2.96 Å) |
Kouba T, Dubankova A, Drncova P, Donati E, Vidossich
P, Speranzini V, Pflug A, Huchting J, Meier C, De Vivo M,
Cusack S |
(2023) "Direct
observation of backtracking by influenza A and B
polymerases upon consecutive incorporation of the
nucleoside analog T1106." Cell Rep,
42, 111901. doi: 10.1016/j.celrep.2022.111901.
|
Early transcription elongation state of influenza
a-h7n9 polymerase stalled with incoming gtp analogue .
SNAP output
|
|
8bf7
|
translation |
cryo-EM (2.33 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Elongating e. coli 70s ribosome containing deacylated
trna(imet) in the p-site and aaa mrna codon with
cognate dipeptidyl-trna(lys) in the a-site . SNAP output
|
|
8bf8
|
RNA binding protein |
cryo-EM (2.8 Å) |
Sasnauskas G, Tamulaitiene G, Druteika G, Carabias A,
Silanskas A, Kazlauskas D, Venclovas C, Montoya G,
Karvelis T, Siksnys V |
(2023) "TnpB
structure reveals minimal functional core of Cas12
nuclease family." Nature,
616, 384-389. doi: 10.1038/s41586-023-05826-x.
|
Isdra2 tnpb in complex with rerna . SNAP output
|
|
8bf9
|
transport protein |
cryo-EM (2.69 Å) |
Karki S, Javanainen M, Rehan S, Tranter D, Kellosalo
J, Huiskonen JT, Happonen L, Paavilainen V |
(2023) "Molecular
view of ER membrane remodeling by the Sec61/TRAP
translocon." Embo Rep.,
24, e57910. doi: 10.15252/embr.202357910.
|
Molecular view of er membrane remodeling by the
sec61-trap translocon. . SNAP output
|
|
8bge
|
translation |
cryo-EM (2.11 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Elongating e. coli 70s ribosome containing acylated
trna(imet) in the p-site and aam6a mrna codon in the
a-site after uncompleted di-peptide formation .
SNAP output
|
|
8bgh
|
translation |
cryo-EM (2.88 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Elongating e. coli 70s ribosome containing acylated
trna(imet) in the p-site and aaa mrna codon in the
a-site after uncompleted di-peptide formation .
SNAP output
|
|
8bgu
|
RNA binding protein |
cryo-EM (4.1 Å) |
Castillo Duque de Estrada NM, Thoms M, Flemming D,
Hammaren HM, Buschauer R, Ameismeier M, Bassler J, Beck
M, Beckmann R, Hurt E |
(2023) "Structure
of nascent 5S RNPs at the crossroad between ribosome
assembly and MDM2-p53 pathways."
Nat.Struct.Mol.Biol., 30,
1119-1131. doi: 10.1038/s41594-023-01006-7.
|
Human mdm2-5s rnp . SNAP
output
|
|
8bh4
|
translation |
cryo-EM (2.62 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Elongating e. coli 70s ribosome containing deacylated
trna(imet) in the p-site and aam6a mrna codon with
cognate dipeptidyl-trna(lys) in the a-site . SNAP output
|
|
8bh6
|
translation |
cryo-EM (3.7 Å) |
Garaeva N, Usachev K |
(2023) "Ribosome maturation factor P (RimP) from
Staphylococcus aureus." Structure. |
Mature 30s ribosomal subunit from staphylococcus aureus
. SNAP output
|
|
8bh7
|
translation |
cryo-EM (4.23 Å) |
Garaeva N, Usachev K |
(2023) "Ribosome maturation factor P (RimP) from
Staphylococcus aureus." Structure. |
The complex of immature 30s ribosomal subunit with
ribosome maturation factor p (rimp) from staphylococcus
aureus . SNAP output
|
|
8bh8
|
RNA binding protein |
X-ray (2.88 Å) |
Rety S, Chen WF, Xi XG |
"Structure of Est1 from Candida Tropicalis in complex
with TLC1 telomerase RNA fragment 444-456." |
Structure of est1 from candida tropicalis in complex
with tlc1 telomerase RNA fragment 444-456 . SNAP output
|
|
8bh9
|
RNA binding protein |
X-ray (2.09 Å) |
Rety S, Chen WF, Xi XG |
"Structure of Est1 from Candida Tropicalis in complex
with TLC1 telomerase RNA fragment 427-435 /
496-504." |
Structure of est1 from candida tropicalis in complex
with tlc1 telomerase RNA fragment 427-435 - 496-504 .
SNAP output
|
|
8bhf
|
ribosome |
cryo-EM (3.1 Å) |
Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones
DR, Sobolevsky AI |
(2023) "Modulation
of GluA2-gamma 5 synaptic complex desensitization,
polyamine block and antiepileptic perampanel inhibition
by auxiliary subunit cornichon-2."
Nat.Struct.Mol.Biol., 30,
1481-1494. doi: 10.1038/s41594-023-01080-x.
|
cryo-EM structure of stalled rabbit 80s ribosomes in
complex with human ccr4-not and cnot4 . SNAP output
|
|
8bhj
|
translation |
cryo-EM (2.81 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Elongating e. coli 70s ribosome containing deacylated
trna(imet) in the p-site and am6aa mrna codon with
cognate dipeptidyl-trna(lys) in the a-site . SNAP output
|
|
8bhl
|
translation |
cryo-EM (2.21 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Elongating e. coli 70s ribosome containing acylated
trna(imet) in the p-site and am6aa mrna codon in the
a-site after uncompleted di-peptide formation .
SNAP output
|
|
8bhn
|
translation |
cryo-EM (2.85 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Elongating e. coli 70s ribosome containing deacylated
trna(imet) in the p-site and m6aaa mrna codon with
cognate dipeptidyl-trna(lys) in the a-site . SNAP output
|
|
8bhp
|
translation |
cryo-EM (2.37 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Elongating e. coli 70s ribosome containing acylated
trna(imet) in the p-site and m6aaa mrna codon in the
a-site after uncompleted di-peptide formation .
SNAP output
|
|
8bil
|
translation |
cryo-EM (2.04 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Initiation complex of the e. coli 70s ribosome with
mrna containing aaa codon in the a-site. . SNAP output
|
|
8bim
|
translation |
cryo-EM (2.04 Å) |
Jain S, Koziej L, Poulis P, Kaczmarczyk I, Gaik M,
Rawski M, Ranjan N, Glatt S, Rodnina MV |
(2023) "Modulation
of translational decoding by m 6 A modification of
mRNA." Nat Commun, 14,
4784. doi: 10.1038/s41467-023-40422-7.
|
Initiation complex of the e. coli 70s ribosome with
mrna containing aam6a codon in the a-site . SNAP output
|
|
8bip
|
ribosome |
cryo-EM (3.1 Å) |
Knorr AG, Mackens-Kiani T, Musial J, Berninghausen O,
Becker T, Beatrix B, Beckmann R |
(2023) "The
dynamic architecture of Map1- and NatB-ribosome
complexes coordinates the sequential modifications of
nascent polypeptide chains." Plos Biol.,
21, e3001995. doi: 10.1371/journal.pbio.3001995.
|
Structure of a yeast 80s ribosome-bound
n-acetyltransferase b complex . SNAP output
|
|
8bjq
|
ribosome |
cryo-EM (3.8 Å) |
Knorr AG, Mackens-Kiani T, Musial J, Berninghausen O,
Becker T, Beatrix B, Beckmann R |
(2023) "The
dynamic architecture of Map1- and NatB-ribosome
complexes coordinates the sequential modifications of
nascent polypeptide chains." Plos Biol.,
21, e3001995. doi: 10.1371/journal.pbio.3001995.
|
Structure of a yeast 80s ribosome-bound
n-acetyltransferase b complex . SNAP output
|
|
8bmw
|
RNA binding protein |
cryo-EM (3.5 Å) |
Cannone G, Kompaniiets D, Graham S, White MF,
Spagnolo L |
(2023) "Structure
of the Saccharolobus solfataricus type III-D CRISPR
effector." Curr Res Struct Biol,
5, 100098. doi: 10.1016/j.crstbi.2023.100098.
|
Ssocsm . SNAP output
|
|
8bn3
|
ribosome |
cryo-EM (2.4 Å) |
Rauscher R, Eggers C, Dimitrova-Paternoga L, Shankar
V, Rosina A, Cristodero M, Paternoga H, Wilson DN, Leidel
SA, Polacek N |
(2024) "Evolving
precision: rRNA expansion segment 7S modulates
translation velocity and accuracy in eukaryal
ribosomes." Nucleic Acids Res.,
52, 4021-4036. doi: 10.1093/nar/gkae067.
|
Yeast 80s, es7s delta, eif5a, stm1 containing .
SNAP output
|
|
8bpo
|
ribosome |
cryo-EM (2.8 Å) |
Hopfler M, Absmeier E, Peak-Chew SY, Vartholomaiou E,
Passmore LA, Gasic I, Hegde RS |
(2023) "Mechanism
of ribosome-associated mRNA degradation during tubulin
autoregulation." Mol.Cell,
83, 2290. doi: 10.1016/j.molcel.2023.05.020.
|
Structure of rabbit 80s ribosome translating
beta-tubulin in complex with tetratricopeptide protein
5 (ttc5) and s-phase cyclin a associated protein
residing in the er (scaper) . SNAP output
|
|
8bqd
|
ribosome |
cryo-EM (3.9 Å) |
Knorr AG, Mackens-Kiani T, Musial J, Berninghausen O,
Becker T, Beatrix B, Beckmann R |
(2023) "The
dynamic architecture of Map1- and NatB-ribosome
complexes coordinates the sequential modifications of
nascent polypeptide chains." Plos Biol.,
21, e3001995. doi: 10.1371/journal.pbio.3001995.
|
Yeast 80s ribosome in complex with map1 (conformation
1) . SNAP output
|
|
8bqx
|
ribosome |
cryo-EM (3.8 Å) |
Knorr AG, Mackens-Kiani T, Musial J, Berninghausen O,
Becker T, Beatrix B, Beckmann R |
(2023) "The
dynamic architecture of Map1- and NatB-ribosome
complexes coordinates the sequential modifications of
nascent polypeptide chains." Plos Biol.,
21, e3001995. doi: 10.1371/journal.pbio.3001995.
|
Yeast 80s ribosome in complex with map1 (conformation
2) . SNAP output
|
|
8br8
|
ribosome |
cryo-EM (3.35 Å) |
Majumdar S, Emmerich A, Krakovka S, Mandava CS, Svard
SG, Sanyal S |
(2023) "Insights
into translocation mechanism and ribosome evolution
from cryo-EM structures of translocation intermediates
of Giardia intestinalis." Nucleic Acids
Res., 51, 3436-3451. doi:
10.1093/nar/gkad176.
|
Giardia ribosome in post-t state (a1) . SNAP output
|
|
8brm
|
ribosome |
cryo-EM (3.33 Å) |
Majumdar S, Emmerich A, Krakovka S, Mandava CS, Svard
SG, Sanyal S |
(2023) "Insights
into translocation mechanism and ribosome evolution
from cryo-EM structures of translocation intermediates
of Giardia intestinalis." Nucleic Acids
Res., 51, 3436-3451. doi:
10.1093/nar/gkad176.
|
Giardia ribosome in post-t state, no e-site trna (a6) .
SNAP output
|
|
8bsi
|
ribosome |
cryo-EM (3.4 Å) |
Majumdar S, Emmerich A, Krakovka S, Mandava CS, Svard
SG, Sanyal S |
(2023) "Insights
into translocation mechanism and ribosome evolution
from cryo-EM structures of translocation intermediates
of Giardia intestinalis." Nucleic Acids
Res., 51, 3436-3451. doi:
10.1093/nar/gkad176.
|
Giardia ribosome chimeric hybrid-like gdp+pi bound
state (b1) . SNAP
output
|
|
8bsj
|
ribosome |
cryo-EM (6.49 Å) |
Majumdar S, Emmerich A, Krakovka S, Mandava CS, Svard
SG, Sanyal S |
(2023) "Insights
into translocation mechanism and ribosome evolution
from cryo-EM structures of translocation intermediates
of Giardia intestinalis." Nucleic Acids
Res., 51, 3436-3451. doi:
10.1093/nar/gkad176.
|
Giardia ribosome in pre-t classical state (c) .
SNAP output
|
|
8btd
|
ribosome |
cryo-EM (4.9 Å) |
Majumdar S, Emmerich A, Krakovka S, Mandava CS, Svard
SG, Sanyal S |
(2023) "Insights
into translocation mechanism and ribosome evolution
from cryo-EM structures of translocation intermediates
of Giardia intestinalis." Nucleic Acids
Res., 51, 3436-3451. doi:
10.1093/nar/gkad176.
|
Giardia ribosome in pre-t hybrid state (d1) . SNAP output
|
|
8btk
|
translocase |
cryo-EM (3.5 Å) |
Jaskolowski M, Jomaa A, Gamerdinger M, Shrestha S,
Leibundgut M, Deuerling E, Ban N |
(2023) "Molecular
basis of the TRAP complex function in ER protein
biogenesis." Nat.Struct.Mol.Biol.,
30, 770-777. doi: 10.1038/s41594-023-00990-0.
|
Structure of the trap complex with the sec translocon
and a translating ribosome . SNAP output
|
|
8btr
|
ribosome |
cryo-EM (3.25 Å) |
Majumdar S, Emmerich A, Krakovka S, Mandava CS, Svard
SG, Sanyal S |
(2023) "Insights
into translocation mechanism and ribosome evolution
from cryo-EM structures of translocation intermediates
of Giardia intestinalis." Nucleic Acids
Res., 51, 3436-3451. doi:
10.1093/nar/gkad176.
|
Giardia ribosome in pre-t hybrid state (d2) . SNAP output
|
|
8buu
|
ribosome |
cryo-EM (2.9 Å) |
Obana N, Takada H, Crowe-McAuliffe C, Iwamoto M,
Egorov AA, Wu KJY, Chiba S, Murina V, Paternoga H, Tresco
BIC, Nomura N, Myers AG, Atkinson GC, Wilson DN,
Hauryliuk V |
(2023) "Genome-encoded
ABCF factors implicated in intrinsic antibiotic
resistance in Gram-positive bacteria: VmlR2, Ard1 and
CplR." Nucleic Acids Res.,
51, 4536-4554. doi: 10.1093/nar/gkad193.
|
Are-abcf vmlr2 bound to a 70s ribosome . SNAP output
|
|
8bvh
|
RNA binding protein |
cryo-EM (3.6 Å) |
Dendooven T, Sonnleitner E, Blasi U, Luisi BF |
(2023) "Translational
regulation by Hfq-Crc assemblies emerges from
polymorphic ribonucleoprotein folding." Embo
J., 42, e111129. doi: 10.15252/embj.2022111129.
|
cryo-EM structure of the hfq-crc-amie translation
repression assembly. . SNAP output
|
|
8bvj
|
RNA binding protein |
cryo-EM (4.5 Å) |
Dendooven T, Sonnleitner E, Blasi U, Luisi BF |
(2023) "Translational
regulation by Hfq-Crc assemblies emerges from
polymorphic ribonucleoprotein folding." Embo
J., 42, e111129. doi: 10.15252/embj.2022111129.
|
Hfq-crc-esta translation repression complex . SNAP output
|
|
8bvm
|
RNA binding protein |
cryo-EM (3.8 Å) |
Dendooven T, Sonnleitner E, Blasi U, Luisi BF |
(2023) "Translational
regulation by Hfq-Crc assemblies emerges from
polymorphic ribonucleoprotein folding." Embo
J., 42, e111129. doi: 10.15252/embj.2022111129.
|
cryo-EM structure of hfq-crc-rbsb translation
repression complex . SNAP output
|
|
8byv
|
ribosome |
cryo-EM (2.89 Å) |
Bikmullin AG, Fatkhullin B, Stetsenko A, Gabdulkhakov
A, Garaeva N, Nurullina L, Klochkova E, Golubev A,
Khusainov I, Trachtmann N, Blokhin D, Guskov A, Validov
S, Usachev K, Yusupov M |
(2023) "Yet
Another Similarity between Mitochondrial and Bacterial
Ribosomal Small Subunit Biogenesis Obtained by
Structural Characterization of RbfA from S.
aureus." Int J Mol Sci,
24. doi: 10.3390/ijms24032118.
|
cryo-EM structure of a staphylococus aureus 30s-rbfa
complex . SNAP
output
|
|
8c00
|
ribosome |
cryo-EM (2.9 Å) |
Poll G, Griesenbeck J, Tschochner H, Milkereit P |
(2023) "Impact
of the yeast S0/uS2-cluster ribosomal protein
rpS21/eS21 on rRNA folding and the architecture of
small ribosomal subunit precursors." Plos
One, 18, e0283698. doi: 10.1371/journal.pone.0283698.
|
Enp1tap-s21_a population of yeast small ribosomal
subunit precursors depleted of rps21-es21 . SNAP output
|
|
8c01
|
ribosome |
cryo-EM (2.7 Å) |
Poll G, Griesenbeck J, Tschochner H, Milkereit P |
(2023) "Impact
of the yeast S0/uS2-cluster ribosomal protein
rpS21/eS21 on rRNA folding and the architecture of
small ribosomal subunit precursors." Plos
One, 18, e0283698. doi: 10.1371/journal.pone.0283698.
|
Enp1tap_a population of yeast small ribosomal subunit
precursors . SNAP
output
|
|
8c3a
|
ribosome |
X-ray (3.0 Å) |
Kolosova O, Zgadzay Y, Wu C, Validov S, Usachev K,
Jenner L, Sachs MS, Yusupova G, Yusupov M |
"New crystal system to promote screening for new
eukaryotic inhibitors." |
Crystal structure of ailanthone bound to the candida
albicans 80s ribosome . SNAP output
|
|
8c4h
|
viral protein |
cryo-EM (3.485 Å) |
Passchier TC, White JBR, Maskell DP, Byrne MJ, Ranson
NA, Edwards TA, Barr JN |
(2024) "The
cryoEM structure of the Hendra henipavirus
nucleoprotein reveals insights into paramyxoviral
nucleocapsid architectures." Sci Rep,
14, 14099. doi: 10.1038/s41598-024-58243-z.
|
Cryoem structure of the hendra henipavirus nucleocapsid
sauronoid assembly multimer . SNAP output
|
|
8c4t
|
viral protein |
cryo-EM (3.23 Å) |
Durieux Trouilleton Q, Barata-Garcia S, Arragain B,
Reguera J, Malet H |
(2023) "Structures
of active Hantaan virus polymerase uncover the
mechanisms of Hantaviridae genome replication."
Nat Commun, 14, 2954. doi:
10.1038/s41467-023-38555-w.
|
Hantaan virus polymerase bound to its 5' viral RNA .
SNAP output
|
|
8c4u
|
viral protein |
cryo-EM (3.36 Å) |
Durieux Trouilleton Q, Barata-Garcia S, Arragain B,
Reguera J, Malet H |
(2023) "Structures
of active Hantaan virus polymerase uncover the
mechanisms of Hantaviridae genome replication."
Nat Commun, 14, 2954. doi:
10.1038/s41467-023-38555-w.
|
Hantaan virus polymerase in replication pre-initiation
state . SNAP output
|
|
8c4v
|
viral protein |
cryo-EM (3.14 Å) |
Durieux Trouilleton Q, Barata-Garcia S, Arragain B,
Reguera J, Malet H |
(2023) "Structures
of active Hantaan virus polymerase uncover the
mechanisms of Hantaviridae genome replication."
Nat Commun, 14, 2954. doi:
10.1038/s41467-023-38555-w.
|
Hantaan virus polymerase in replication elongation
state . SNAP output
|
|
8c6j
|
splicing |
cryo-EM (2.8 Å) |
Dybkov O, Preussner M, El Ayoubi L, Feng VY, Harnisch
C, Merz K, Leupold P, Yudichev P, Agafonov DE, Will CL,
Girard C, Dienemann C, Urlaub H, Kastner B, Heyd F,
Luehrmann R |
(2023) "Regulation
of 3' splice site selection after step 1 of splicing by
spliceosomal C* proteins." Sci Adv,
9, eadf1785. doi: 10.1126/sciadv.adf1785.
|
Human spliceosomal pm5 c* complex . SNAP output
|
|
8c83
|
ribosome |
cryo-EM (3.0 Å) |
Ikeuchi K, Ivic N, Buschauer R, Cheng J, Frohlich T,
Matsuo Y, Berninghausen O, Inada T, Becker T, Beckmann
R |
(2023) "Molecular
basis for recognition and deubiquitination of 40S
ribosomes by Otu2." Nat Commun,
14, 2730. doi: 10.1038/s41467-023-38161-w.
|
cryo-EM structure of in vitro reconstituted otu2-bound
ub-40s complex . SNAP
output
|
|
8c8h
|
viral protein |
cryo-EM (3.84 Å) |
Grimm G, Bartuli J, Fischer U |
"Cryo EM structure of the vaccinia complete RNA
polymerase complex lacking the capping enzyme." |
Cryo em structure of the vaccinia complete RNA
polymerase complex lacking the capping enzyme .
SNAP output
|
|
8c8x
|
ribosome |
cryo-EM (3.93 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c8y
|
ribosome |
cryo-EM (3.03 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c8z
|
ribosome |
cryo-EM (3.12 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c90
|
ribosome |
cryo-EM (3.15 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c91
|
ribosome |
cryo-EM (4.19 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c92
|
ribosome |
cryo-EM (3.79 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c93
|
ribosome |
cryo-EM (4.17 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c94
|
ribosome |
cryo-EM (3.8 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c95
|
ribosome |
cryo-EM (4.92 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c96
|
ribosome |
cryo-EM (4.43 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c97
|
ribosome |
cryo-EM (4.07 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c98
|
ribosome |
cryo-EM (3.66 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c99
|
ribosome |
cryo-EM (3.29 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c9a
|
ribosome |
cryo-EM (4.86 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c9b
|
ribosome |
cryo-EM (5.9 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8c9c
|
ribosome |
cryo-EM (6.62 Å) |
Qin B, Lauer SM, Balke A, Vieira-Vieira CH, Burger J,
Mielke T, Selbach M, Scheerer P, Spahn CMT, Nikolay
R |
(2023) "Cryo-EM
captures early ribosome assembly in action."
Nat Commun, 14, 898. doi:
10.1038/s41467-023-36607-9.
|
cryo-EM captures early ribosome assembly in action .
SNAP output
|
|
8ca7
|
ribosome |
cryo-EM (2.06 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Omadacycline and spectinomycin bound to the 30s
ribosomal subunit head . SNAP output
|
|
8cah
|
ribosome |
cryo-EM (3.0 Å) |
Ikeuchi K, Ivic N, Buschauer R, Cheng J, Frohlich T,
Matsuo Y, Berninghausen O, Inada T, Becker T, Beckmann
R |
(2023) "Molecular
basis for recognition and deubiquitination of 40S
ribosomes by Otu2." Nat Commun,
14, 2730. doi: 10.1038/s41467-023-38161-w.
|
cryo-EM structure of native otu2-bound ubiquitinated
43s pre-initiation complex . SNAP output
|
|
8cai
|
ribosome |
cryo-EM (2.08 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Streptomycin and hygromycin b bound to the 30s body .
SNAP output
|
|
8cam
|
ribosome |
cryo-EM (1.86 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Evernimicin bound to the 50s subunit . SNAP output
|
|
8cas
|
ribosome |
cryo-EM (3.3 Å) |
Ikeuchi K, Ivic N, Buschauer R, Cheng J, Frohlich T,
Matsuo Y, Berninghausen O, Inada T, Becker T, Beckmann
R |
(2023) "Molecular
basis for recognition and deubiquitination of 40S
ribosomes by Otu2." Nat Commun,
14, 2730. doi: 10.1038/s41467-023-38161-w.
|
cryo-EM structure of native otu2-bound ubiquitinated
48s initiation complex (partial) . SNAP output
|
|
8caz
|
ribosome |
cryo-EM (2.11 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Empty 30s head . SNAP
output
|
|
8cbj
|
ribosome |
cryo-EM (3.8 Å) |
Ikeuchi K, Ivic N, Buschauer R, Cheng J, Frohlich T,
Matsuo Y, Berninghausen O, Inada T, Becker T, Beckmann
R |
(2023) "Molecular
basis for recognition and deubiquitination of 40S
ribosomes by Otu2." Nat Commun,
14, 2730. doi: 10.1038/s41467-023-38161-w.
|
cryo-EM structure of otu2-bound cytoplasmic pre-40s
ribosome biogenesis complex . SNAP output
|
|
8cbk
|
RNA binding protein |
cryo-EM (2.76 Å) |
Meynier V, Hardwick SW, Catala M, Roske JJ, Oerum S,
Chirgadze DY, Barraud P, Yue WW, Luisi BF, Tisne C |
(2024) "Structural
basis for human mitochondrial tRNA maturation."
Nat Commun, 15, 4683. doi:
10.1038/s41467-024-49132-0.
|
Structure of human mitochondrial rnase p in complex
with mitochondrial pre-trna-his(5,ser) . SNAP output
|
|
8cbl
|
RNA binding protein |
cryo-EM (2.79 Å) |
Meynier V, Hardwick SW, Catala M, Roske JJ, Oerum S,
Chirgadze DY, Barraud P, Yue WW, Luisi BF, Tisne C |
(2024) "Structural
basis for human mitochondrial tRNA maturation."
Nat Commun, 15, 4683. doi:
10.1038/s41467-024-49132-0.
|
Structure of human mitochondrial rnase z in complex
with mitochondrial pre-trna-his(0,ser) . SNAP output
|
|
8cbm
|
RNA binding protein |
cryo-EM (3.14 Å) |
Meynier V, Hardwick SW, Catala M, Roske JJ, Oerum S,
Chirgadze DY, Barraud P, Yue WW, Luisi BF, Tisne C |
(2024) "Structural
basis for human mitochondrial tRNA maturation."
Nat Commun, 15, 4683. doi:
10.1038/s41467-024-49132-0.
|
Structure of human mitochondrial cca-adding enzyme in
complex with mitochondrial pre-trna-ile . SNAP output
|
|
8cbo
|
RNA binding protein |
cryo-EM (3.2 Å) |
Meynier V, Hardwick SW, Catala M, Roske JJ, Oerum S,
Chirgadze DY, Barraud P, Yue WW, Luisi BF, Tisne C |
(2024) "Structural
basis for human mitochondrial tRNA maturation."
Nat Commun, 15, 4683. doi:
10.1038/s41467-024-49132-0.
|
Structure of human mitochondrial mrpp1-mrpp2 in complex
with mitochondrial pre-trna-ile . SNAP output
|
|
8cbw
|
viral protein |
cryo-EM (3.485 Å) |
Passchier TC, White JBR, Maskell DP, Byrne MJ, Ranson
NA, Edwards TA, Barr JN |
(2024) "The
cryoEM structure of the Hendra henipavirus
nucleoprotein reveals insights into paramyxoviral
nucleocapsid architectures." Sci Rep,
14, 14099. doi: 10.1038/s41598-024-58243-z.
|
Cryoem structure of the hendra henipavirus nucleocapsid
sauronoid assembly monomer . SNAP output
|
|
8ccs
|
ribosome |
cryo-EM (1.97 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
80s s. cerevisiae ribosome with ligands in hybrid-1
pre-translocation (pre-h1) complex . SNAP output
|
|
8cd1
|
ribosome |
cryo-EM (3.0 Å) |
Gerovac M, Chihara K, Wicke L, Bottcher B, Lavigne R,
Vogel J |
(2024) "Phage
proteins target and co-opt host ribosomes immediately
upon infection." Nat Microbiol,
9, 787-800. doi: 10.1038/s41564-024-01616-x.
|
70s-phikz014 . SNAP
output
|
|
8cdl
|
ribosome |
cryo-EM (2.72 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
80s s. cerevisiae ribosome with ligands in hybrid-2
pre-translocation (pre-h2) complex . SNAP output
|
|
8cdr
|
ribosome |
cryo-EM (2.04 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
Translocation intermediate 2 (ti-2) of 80s s.
cerevisiae ribosome with ligands and eef2 in the
presence of sordarin . SNAP output
|
|
8cdu
|
ribosome |
cryo-EM (3.1 Å) |
Dimitrova-Paternoga L, Kasvandik S, Beckert B,
Granneman S, Tenson T, Wilson DN, Paternoga H |
(2024) "Structural
basis of ribosomal 30S subunit degradation by RNase
R." Nature, 626,
1133-1140. doi: 10.1038/s41586-024-07027-6.
|
Rnase r bound to a 30s degradation intermediate (main
state) . SNAP output
|
|
8cdv
|
ribosome |
cryo-EM (4.73 Å) |
Dimitrova-Paternoga L, Kasvandik S, Beckert B,
Granneman S, Tenson T, Wilson DN, Paternoga H |
(2024) "Structural
basis of ribosomal 30S subunit degradation by RNase
R." Nature, 626,
1133-1140. doi: 10.1038/s41586-024-07027-6.
|
Rnase r bound to a 30s degradation intermediate (state
ii) . SNAP output
|
|
8cec
|
ribosome |
cryo-EM (3.57 Å) |
Dimitrova-Paternoga L, Kasvandik S, Beckert B,
Granneman S, Tenson T, Wilson DN, Paternoga H |
(2024) "Structural
basis of ribosomal 30S subunit degradation by RNase
R." Nature, 626,
1133-1140. doi: 10.1038/s41586-024-07027-6.
|
Rnase r bound to a 30s degradation intermediate (state
i - head-turning) . SNAP
output
|
|
8ced
|
ribosome |
cryo-EM (4.15 Å) |
Dimitrova-Paternoga L, Kasvandik S, Beckert B,
Granneman S, Tenson T, Wilson DN, Paternoga H |
(2024) "Structural
basis of ribosomal 30S subunit degradation by RNase
R." Nature, 626,
1133-1140. doi: 10.1038/s41586-024-07027-6.
|
Rnase r bound to a 30s degradation intermediate (state
i - head-turning) . SNAP
output
|
|
8cee
|
ribosome |
cryo-EM (3.7 Å) |
Dimitrova-Paternoga L, Kasvandik S, Beckert B,
Granneman S, Tenson T, Wilson DN, Paternoga H |
(2024) "Structural
basis of ribosomal 30S subunit degradation by RNase
R." Nature, 626,
1133-1140. doi: 10.1038/s41586-024-07027-6.
|
Rnase r bound to a 30s degradation intermediate (state
i - head-turning) . SNAP
output
|
|
8ceh
|
ribosome |
cryo-EM (2.05 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
Translocation intermediate 4 (ti-4) of 80s s.
cerevisiae ribosome with ligands and eef2 in the
presence of sordarin . SNAP output
|
|
8cep
|
ribosome |
cryo-EM (2.04 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Kasugamycin bound to the 30s body . SNAP output
|
|
8ceu
|
ribosome |
cryo-EM (1.83 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Retapamulin and capreomycin bound to the 50s subunit .
SNAP output
|
|
8cf1
|
ribosome |
cryo-EM (1.82 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Tetracycline bound to the 30s head . SNAP output
|
|
8cf5
|
ribosome |
cryo-EM (2.71 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
Translocation intermediate 1 (ti-1) of 80s s.
cerevisiae ribosome with ligands and eef2 in the
presence of sordarin . SNAP output
|
|
8cf8
|
ribosome |
cryo-EM (2.2 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Eravacycline bound to the 30s head . SNAP output
|
|
8cg8
|
ribosome |
cryo-EM (2.57 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
Translocation intermediate 3 (ti-3) of 80s s.
cerevisiae ribosome with ligands and eef2 in the
presence of sordarin . SNAP output
|
|
8cgd
|
ribosome |
cryo-EM (1.98 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Clindamycin bound to the 50s subunit . SNAP output
|
|
8cgi
|
ribosome |
cryo-EM (1.89 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Pentacycline tp038 bound to the 30s head . SNAP output
|
|
8cgj
|
ribosome |
cryo-EM (1.79 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Streptomycin bound to the 30s body . SNAP output
|
|
8cgk
|
ribosome |
cryo-EM (1.64 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Lincomycin and avilamycin bound to the 50s subunit .
SNAP output
|
|
8cgn
|
ribosome |
cryo-EM (2.28 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
Non-rotated 80s s. cerevisiae ribosome with ligands .
SNAP output
|
|
8cgr
|
ribosome |
cryo-EM (2.12 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Apramycin bound to the 30s body . SNAP output
|
|
8cgu
|
ribosome |
cryo-EM (1.89 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Gentamicin bound to the 30s body . SNAP output
|
|
8cgv
|
ribosome |
cryo-EM (1.66 Å) |
Paternoga H, Crowe-McAuliffe C, Bock LV, Koller TO,
Morici M, Beckert B, Myasnikov AG, Grubmuller H, Novacek
J, Wilson DN |
(2023) "Structural
conservation of antibiotic interaction with
ribosomes." Nat.Struct.Mol.Biol.,
30, 1380-1392. doi: 10.1038/s41594-023-01047-y.
|
Tiamulin bound to the 50s subunit . SNAP output
|
|
8ch6
|
splicing |
cryo-EM (5.9 Å) |
Schmitzova J, Cretu C, Dienemann C, Urlaub H, Pena
V |
(2023) "Structural
basis of catalytic activation in human splicing."
Nature, 617, 842-850. doi:
10.1038/s41586-023-06049-w.
|
Structure of a late-stage activated spliceosome (baqr)
arrested with a dominant-negative aquarius mutant
(state b complex). . SNAP output
|
|
8ci5
|
viral protein |
cryo-EM (3.2 Å) |
Meier K, Thorkelsson SR, Durieux Trouilleton Q, Vogel
D, Yu D, Kosinski J, Cusack S, Malet H, Grunewald K,
Quemin ERJ, Rosenthal M |
(2023) "Structural
and functional characterization of the Sin Nombre virus
L protein." Plos Pathog.,
19, e1011533. doi: 10.1371/journal.ppat.1011533.
|
Structure of the snv l protein bound to 5' RNA .
SNAP output
|
|
8civ
|
ribosome |
cryo-EM (2.47 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
Translocation intermediate 5 (ti-5) of 80s s.
cerevisiae ribosome with ligands and eef2 in the
presence of sordarin . SNAP output
|
|
8cku
|
ribosome |
cryo-EM (3.11 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
Translocation intermediate 1 (ti-1*) of 80s s.
cerevisiae ribosome with ligands and eef2 in the
absence of sordarin . SNAP output
|
|
8cmj
|
ribosome |
cryo-EM (3.79 Å) |
Milicevic N, Jenner L, Myasnikov A, Yusupov M,
Yusupova G |
(2024) "mRNA
reading frame maintenance during eukaryotic ribosome
translocation." Nature,
625, 393-400. doi: 10.1038/s41586-023-06780-4.
|
Translocation intermediate 4 (ti-4*) of 80s s.
cerevisiae ribosome with eef2 in the absence of
sordarin . SNAP
output
|
|
8coo
|
RNA binding protein |
NMR |
Nicastro G, Abis G, Klein P, Esteban-Serna S,
Gallagher C, Chaves-Arquero B, Cai Y, Figueiredo AM,
Martin SR, Patani R, Taylor IA, Ramos A |
(2023) "Direct
m6A recognition by IMP1 underlays an alternative model
of target selection for non-canonical
methyl-readers." Nucleic Acids Res.,
51, 8774-8786. doi: 10.1093/nar/gkad534.
|
Solution structure of zipcode binding protein 1 (zbp1)
kh3(dd)kh4 domains in complex with n6-methyladenosine
containing RNA . SNAP
output
|
|
8cq7
|
ribosome |
X-ray (3.2 Å) |
Kolosova O, Zgadzay Y, Yusupov M |
(2025) "Mechanism of read-through enhancement by
aminoglycosides and mefloquine."
Proc.Natl.Acad.Sci.USA. doi: 10.1073/pnas.2420261122.
|
Crystal structure of phyllanthoside bound to the
candida albicans 80s ribosome . SNAP output
|
|
8cqw
|
ribosome |
X-ray (3.05 Å) |
Kolosova O, Zgadzay Y, Yusupov M |
(2025) "Mechanism of read-through enhancement by
aminoglycosides and mefloquine."
Proc.Natl.Acad.Sci.USA. doi: 10.1073/pnas.2420261122.
|
Crystal structure of the candida albicans 80s ribosome
in complex with hygromycin b . SNAP output
|
|
8cre
|
ribosome |
X-ray (3.0 Å) |
Kolosova O, Zgadzay Y, Yusupov M |
(2025) "Mechanism of read-through enhancement by
aminoglycosides and mefloquine."
Proc.Natl.Acad.Sci.USA. doi: 10.1073/pnas.2420261122.
|
Crystal structure of the candida albicans 80s ribosome
in complex with geneticin g418 . SNAP output
|
|
8crx
|
antibiotic |
cryo-EM (2.78 Å) |
Lomakin IB, Devarkar SC, Patel S, Grada A, Bunick
CG |
(2023) "Sarecycline
inhibits protein translation in Cutibacterium acnes 70S
ribosome using a two-site mechanism." Nucleic
Acids Res., 51, 2915-2930. doi:
10.1093/nar/gkad103.
|
Cutibacterium acnes 70s ribosome with mrna, p-site trna
and sarecycline bound . SNAP output
|
|
8csp
|
ribosome |
cryo-EM (2.66 Å) |
Harper NJ, Burnside C, Klinge S |
(2023) "Principles
of mitoribosomal small subunit assembly in
eukaryotes." Nature, 614,
175-181. doi: 10.1038/s41586-022-05621-0.
|
Human mitochondrial small subunit assembly intermediate
(state a) . SNAP
output
|
|
8csq
|
ribosome |
cryo-EM (2.54 Å) |
Harper NJ, Burnside C, Klinge S |
(2023) "Principles
of mitoribosomal small subunit assembly in
eukaryotes." Nature, 614,
175-181. doi: 10.1038/s41586-022-05621-0.
|
Human mitochondrial small subunit assembly intermediate
(state b) . SNAP
output
|
|
8csr
|
ribosome |
cryo-EM (2.54 Å) |
Harper NJ, Burnside C, Klinge S |
(2023) "Principles
of mitoribosomal small subunit assembly in
eukaryotes." Nature, 614,
175-181. doi: 10.1038/s41586-022-05621-0.
|
Human mitochondrial small subunit assembly intermediate
(state c) . SNAP
output
|
|
8css
|
ribosome |
cryo-EM (2.36 Å) |
Harper NJ, Burnside C, Klinge S |
(2023) "Principles
of mitoribosomal small subunit assembly in
eukaryotes." Nature, 614,
175-181. doi: 10.1038/s41586-022-05621-0.
|
Human mitochondrial small subunit assembly intermediate
(state d) . SNAP
output
|
|
8cst
|
ribosome |
cryo-EM (2.85 Å) |
Harper NJ, Burnside C, Klinge S |
(2023) "Principles
of mitoribosomal small subunit assembly in
eukaryotes." Nature, 614,
175-181. doi: 10.1038/s41586-022-05621-0.
|
Human mitochondrial small subunit assembly intermediate
(state e) . SNAP
output
|
|
8csu
|
ribosome |
cryo-EM (3.03 Å) |
Harper NJ, Burnside C, Klinge S |
(2023) "Principles
of mitoribosomal small subunit assembly in
eukaryotes." Nature, 614,
175-181. doi: 10.1038/s41586-022-05621-0.
|
Human mitochondrial small subunit assembly intermediate
(state c*) . SNAP
output
|
|
8cth
|
transferase-RNA |
cryo-EM (3.3 Å) |
Li J, Wang L, Hahn Q, Nowak RP, Viennet T, Orellana
EA, Roy Burman SS, Yue H, Hunkeler M, Fontana P, Wu H,
Arthanari H, Fischer ES, Gregory RI |
(2023) "Structural
basis of regulated m 7 G tRNA modification by
METTL1-WDR4." Nature,
613, 391-397. doi: 10.1038/s41586-022-05566-4.
|
cryo-EM structure of human mettl1-wdr4-trna(phe)
complex . SNAP
output
|
|
8cti
|
transferase-RNA |
cryo-EM (3.6 Å) |
Li J, Wang L, Hahn Q, Nowak RP, Viennet T, Orellana
EA, Roy Burman SS, Yue H, Hunkeler M, Fontana P, Wu H,
Arthanari H, Fischer ES, Gregory RI |
(2023) "Structural
basis of regulated m 7 G tRNA modification by
METTL1-WDR4." Nature,
613, 391-397. doi: 10.1038/s41586-022-05566-4.
|
cryo-EM structure of human mettl1-wdr4-trna(val)
complex . SNAP
output
|
|
8cvj
|
ribosome-RNA |
X-ray (2.4 Å) |
Syroegin EA, Aleksandrova EV, Polikanov YS |
(2023) "Insights
into the ribosome function from the structures of
non-arrested ribosome-nascent chain complexes."
Nat.Chem., 15, 143-153. doi:
10.1038/s41557-022-01073-1.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with mrna, aminoacylated a-site
phe-nh-trnaphe, peptidyl p-site fmseac-nh-trnamet, and
deacylated e-site trnaphe at 2.40a resolution .
SNAP output
|
|
8cvk
|
ribosome-RNA |
X-ray (2.5 Å) |
Syroegin EA, Aleksandrova EV, Polikanov YS |
(2023) "Insights
into the ribosome function from the structures of
non-arrested ribosome-nascent chain complexes."
Nat.Chem., 15, 143-153. doi:
10.1038/s41557-022-01073-1.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with mrna, aminoacylated a-site
phe-nh-trnaphe, peptidyl p-site fmrc-nh-trnamet, and
deacylated e-site trnaphe at 2.50a resolution .
SNAP output
|
|
8cvl
|
ribosome-RNA |
X-ray (2.3 Å) |
Syroegin EA, Aleksandrova EV, Polikanov YS |
(2023) "Insights
into the ribosome function from the structures of
non-arrested ribosome-nascent chain complexes."
Nat.Chem., 15, 143-153. doi:
10.1038/s41557-022-01073-1.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with mrna, aminoacylated a-site
phe-nh-trnaphe, peptidyl p-site fmthsmrc-nh-trnamet,
and deacylated e-site trnaphe at 2.30a resolution .
SNAP output
|
|
8cvm
|
antibiotic |
cryo-EM (2.66 Å) |
Lomakin IB, Devarkar SC, Patel S, Grada A, Bunick
CG |
(2023) "Sarecycline
inhibits protein translation in Cutibacterium acnes 70S
ribosome using a two-site mechanism." Nucleic
Acids Res., 51, 2915-2930. doi:
10.1093/nar/gkad103.
|
Cutibacterium acnes 50s ribosomal subunit with p-site
trna and sarecycline bound in the local refined map .
SNAP output
|
|
8cvo
|
antibiotic |
cryo-EM (2.95 Å) |
Lomakin IB, Devarkar SC, Patel S, Grada A, Bunick
CG |
(2023) "Sarecycline
inhibits protein translation in Cutibacterium acnes 70S
ribosome using a two-site mechanism." Nucleic
Acids Res., 51, 2915-2930. doi:
10.1093/nar/gkad103.
|
Cutibacterium acnes 30s ribosomal subunit with
sarecycline bound, head domain only in the local
refined map . SNAP
output
|
|
8cwo
|
antibiotic |
cryo-EM (2.84 Å) |
Lomakin IB, Devarkar SC, Patel S, Grada A, Bunick
CG |
(2023) "Sarecycline
inhibits protein translation in Cutibacterium acnes 70S
ribosome using a two-site mechanism." Nucleic
Acids Res., 51, 2915-2930. doi:
10.1093/nar/gkad103.
|
Cutibacterium acnes 30s ribosomal subunit with
sarecycline bound, body domain only in the local
refined map . SNAP
output
|
|
8cx0
|
viral protein-immune system-RNA |
cryo-EM (2.7 Å) |
Li YL, Langley CA, Azumaya CM, Echeverria I,
Chesarino NM, Emerman M, Cheng Y, Gross JD |
(2023) "The
structural basis for HIV-1 Vif antagonism of human
APOBEC3G." Nature, 615,
728-733. doi: 10.1038/s41586-023-05779-1.
|
cryo-EM structure of human apobec3g-hiv-1
vif-cbfbeta-elob-eloc monomeric complex . SNAP output
|
|
8cx1
|
viral protein-immune system-RNA |
cryo-EM (3.3 Å) |
Li YL, Langley CA, Azumaya CM, Echeverria I,
Chesarino NM, Emerman M, Cheng Y, Gross JD |
(2023) "The
structural basis for HIV-1 Vif antagonism of human
APOBEC3G." Nature, 615,
728-733. doi: 10.1038/s41586-023-05779-1.
|
cryo-EM structure of human apobec3g-hiv-1
vif-cbfbeta-elob-eloc dimeric complex in state 1 .
SNAP output
|
|
8cx2
|
viral protein-immune system-RNA |
cryo-EM (3.2 Å) |
Li YL, Langley CA, Azumaya CM, Echeverria I,
Chesarino NM, Emerman M, Cheng Y, Gross JD |
(2023) "The
structural basis for HIV-1 Vif antagonism of human
APOBEC3G." Nature, 615,
728-733. doi: 10.1038/s41586-023-05779-1.
|
cryo-EM structure of human apobec3g-hiv-1
vif-cbfbeta-elob-eloc dimeric complex in state 2 .
SNAP output
|
|
8d1v
|
RNA binding protein-RNA |
cryo-EM (2.82 Å) |
Goswami HN, Rai J, Das A, Li H |
(2022) "Molecular
mechanism of active Cas7-11 in processing CRISPR RNA
and interfering target RNA." Elife,
11. doi: 10.7554/eLife.81678.
|
cryo-EM structure of guide RNA and target RNA bound
cas7-11 . SNAP
output
|
|
8d29
|
RNA-immune system |
X-ray (1.81 Å) |
Menichelli E, Lam BJ, Wang Y, Wang VS, Shaffer J,
Tjhung KF, Bursulaya B, Nguyen TN, Vo T, Alper PB,
McAllister CS, Jones DH, Spraggon G, Michellys PY, Joslin
J, Joyce GF, Rogers J |
(2022) "Discovery
of small molecules that target a tertiary-structured
RNA." Proc.Natl.Acad.Sci.USA,
119, e2213117119. doi: 10.1073/pnas.2213117119.
|
Crystal structure of theophylline aptamer - apo form .
SNAP output
|
|
8d49
|
DNA binding protein-RNA |
cryo-EM (3.2 Å) |
Bravo JPK, Hallmark T, Naegle B, Beisel CL, Jackson
RN, Taylor DW |
(2023) "RNA
targeting unleashes indiscriminate nuclease activity of
CRISPR-Cas12a2." Nature,
613, 582-587. doi: 10.1038/s41586-022-05560-w.
|
Structure of cas12a2 binary complex . SNAP output
|
|
8d4b
|
DNA binding protein-RNA |
cryo-EM (2.92 Å) |
Bravo JPK, Hallmark T, Naegle B, Beisel CL, Jackson
RN, Taylor DW |
(2023) "RNA
targeting unleashes indiscriminate nuclease activity of
CRISPR-Cas12a2." Nature,
613, 582-587. doi: 10.1038/s41586-022-05560-w.
|
Structure of cas12a2 ternary complex . SNAP output
|
|
8d6j
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Xiao Y, Liu TM, MacRae IJ |
(2023) "A tiny
loop in the Argonaute PIWI domain tunes small RNA seed
strength." Embo Rep., 24,
e55806. doi: 10.15252/embr.202255806.
|
Human ago2 bound to mir122(21nt) with piwi loop swapped
to atago10 sequence . SNAP output
|
|
8d71
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Xiao Y, Liu TM, MacRae IJ |
(2023) "A tiny
loop in the Argonaute PIWI domain tunes small RNA seed
strength." Embo Rep., 24,
e55806. doi: 10.15252/embr.202255806.
|
Human ago2 bound to mir122(21nt) . SNAP output
|
|
8d8j
|
ribosome |
cryo-EM (3.8 Å) |
Harper NJ, Burnside C, Klinge S |
(2023) "Principles
of mitoribosomal small subunit assembly in
eukaryotes." Nature, 614,
175-181. doi: 10.1038/s41586-022-05621-0.
|
Yeast mitochondrial small subunit assembly intermediate
(state 1) . SNAP
output
|
|
8d8k
|
ribosome |
cryo-EM (3.13 Å) |
Harper NJ, Burnside C, Klinge S |
(2023) "Principles
of mitoribosomal small subunit assembly in
eukaryotes." Nature, 614,
175-181. doi: 10.1038/s41586-022-05621-0.
|
Yeast mitochondrial small subunit assembly intermediate
(state 2) . SNAP
output
|
|
8d8l
|
ribosome |
cryo-EM (2.6 Å) |
Harper NJ, Burnside C, Klinge S |
(2023) "Principles
of mitoribosomal small subunit assembly in
eukaryotes." Nature, 614,
175-181. doi: 10.1038/s41586-022-05621-0.
|
Yeast mitochondrial small subunit assembly intermediate
(state 3) . SNAP
output
|
|
8d8n
|
RNA binding protein-RNA |
cryo-EM (3.6 Å) |
Hu C, van Beljouw SPB, Nam KH, Schuler G, Ding F, Cui
Y, Rodriguez-Molina A, Haagsma AC, Valk M, Pabst M,
Brouns SJJ, Ke A |
(2022) "Craspase
is a CRISPR RNA-guided, RNA-activated protease."
Science, 377, 1278-1285. doi:
10.1126/science.add5064.
|
Gramp non-match pfs target RNA . SNAP output
|
|
8d97
|
RNA binding protein-RNA |
cryo-EM (3.8 Å) |
Hu C, van Beljouw SPB, Nam KH, Schuler G, Ding F, Cui
Y, Rodriguez-Molina A, Haagsma AC, Valk M, Pabst M,
Brouns SJJ, Ke A |
(2022) "Craspase
is a CRISPR RNA-guided, RNA-activated protease."
Science, 377, 1278-1285. doi:
10.1126/science.add5064.
|
Apo gramp . SNAP
output
|
|
8d9e
|
RNA binding protein-RNA |
cryo-EM (3.76 Å) |
Hu C, van Beljouw SPB, Nam KH, Schuler G, Ding F, Cui
Y, Rodriguez-Molina A, Haagsma AC, Valk M, Pabst M,
Brouns SJJ, Ke A |
(2022) "Craspase
is a CRISPR RNA-guided, RNA-activated protease."
Science, 377, 1278-1285. doi:
10.1126/science.add5064.
|
Gramp-match pfs target . SNAP output
|
|
8d9f
|
RNA binding protein-RNA |
cryo-EM (2.71 Å) |
Hu C, van Beljouw SPB, Nam KH, Schuler G, Ding F, Cui
Y, Rodriguez-Molina A, Haagsma AC, Valk M, Pabst M,
Brouns SJJ, Ke A |
(2022) "Craspase
is a CRISPR RNA-guided, RNA-activated protease."
Science, 377, 1278-1285. doi:
10.1126/science.add5064.
|
Gramp-tpr-chat (craspase) . SNAP output
|
|
8d9g
|
RNA binding protein-RNA |
cryo-EM (2.57 Å) |
Hu C, van Beljouw SPB, Nam KH, Schuler G, Ding F, Cui
Y, Rodriguez-Molina A, Haagsma AC, Valk M, Pabst M,
Brouns SJJ, Ke A |
(2022) "Craspase
is a CRISPR RNA-guided, RNA-activated protease."
Science, 377, 1278-1285. doi:
10.1126/science.add5064.
|
Gramp-tpr-chat non match pfs target RNA(craspase) .
SNAP output
|
|
8d9h
|
RNA binding protein-RNA |
cryo-EM (3.6 Å) |
Hu C, van Beljouw SPB, Nam KH, Schuler G, Ding F, Cui
Y, Rodriguez-Molina A, Haagsma AC, Valk M, Pabst M,
Brouns SJJ, Ke A |
(2022) "Craspase
is a CRISPR RNA-guided, RNA-activated protease."
Science, 377, 1278-1285. doi:
10.1126/science.add5064.
|
Gramp-tpr-chat match pfs target RNA(craspase) .
SNAP output
|
|
8d9i
|
RNA binding protein-RNA |
cryo-EM (3.62 Å) |
Hu C, van Beljouw SPB, Nam KH, Schuler G, Ding F, Cui
Y, Rodriguez-Molina A, Haagsma AC, Valk M, Pabst M,
Brouns SJJ, Ke A |
(2022) "Craspase
is a CRISPR RNA-guided, RNA-activated protease."
Science, 377, 1278-1285. doi:
10.1126/science.add5064.
|
Gramp non-matching pfs-with mg . SNAP output
|
|
8d9k
|
transferase |
cryo-EM (3.72 Å) |
Ruiz-Arroyo VM, Raj R, Babu K, Onolbaatar O, Roberts
PH, Nam Y |
(2023) "Structures
and mechanisms of tRNA methylation by METTL1-WDR4."
Nature, 613, 383-390. doi:
10.1038/s41586-022-05565-5.
|
Cryoem structure of human mettl1-wdr4 in complex with
lys-trna . SNAP
output
|
|
8d9l
|
transferase-RNA |
cryo-EM (4.04 Å) |
Ruiz-Arroyo VM, Raj R, Babu K, Onolbaatar O, Roberts
PH, Nam Y |
(2023) "Structures
and mechanisms of tRNA methylation by METTL1-WDR4."
Nature, 613, 383-390. doi:
10.1038/s41586-022-05565-5.
|
Cryoem structure of human mettl1-wdr4 in complex with
lys-trna and sam . SNAP
output
|
|
8dex
|
RNA binding protein-RNA |
cryo-EM (2.7 Å) |
O'Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright
JT, Taylor DW |
(2023) "Structural
snapshots of R-loop formation by a type I-C CRISPR
Cascade." Mol.Cell, 83,
746. doi: 10.1016/j.molcel.2023.01.024.
|
Type i-c cascade . SNAP
output
|
|
8dfo
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
O'Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright
JT, Taylor DW |
(2023) "Structural
snapshots of R-loop formation by a type I-C CRISPR
Cascade." Mol.Cell, 83,
746. doi: 10.1016/j.molcel.2023.01.024.
|
Type i-c cascade bound to acric4 . SNAP output
|
|
8dfs
|
RNA binding protein-RNA |
cryo-EM (3.0 Å) |
O'Brien RE, Bravo JPK, Ramos D, Hibshman GN, Wright
JT, Taylor DW |
(2023) "Structural
snapshots of R-loop formation by a type I-C CRISPR
Cascade." Mol.Cell, 83,
746. doi: 10.1016/j.molcel.2023.01.024.
|
Type i-c cascade bound to acrif2 . SNAP output
|
|
8dfv
|
RNA binding protein-RNA |
cryo-EM (3.06 Å) |
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall
TMT, Zamore PD, Korostelev AA |
(2022) "Structural
basis of microRNA biogenesis by Dicer-1 and its partner
protein Loqs-PB." Mol.Cell,
82, 4049-4063.e6. doi: 10.1016/j.molcel.2022.09.002.
|
Structural basis of microrna biogenesis by dicer-1 and
its partner protein loqs-pb - complex iia . SNAP output
|
|
8dg5
|
RNA binding protein-RNA |
cryo-EM (3.26 Å) |
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall
TMT, Zamore PD, Korostelev AA |
(2022) "Structural
basis of microRNA biogenesis by Dicer-1 and its partner
protein Loqs-PB." Mol.Cell,
82, 4049-4063.e6. doi: 10.1016/j.molcel.2022.09.002.
|
Structural basis of microrna biogenesis by dicer-1 and
its partner protein loqs-pb - complex iib . SNAP output
|
|
8dg7
|
RNA binding protein-RNA |
cryo-EM (3.32 Å) |
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall
TMT, Zamore PD, Korostelev AA |
(2022) "Structural
basis of microRNA biogenesis by Dicer-1 and its partner
protein Loqs-PB." Mol.Cell,
82, 4049-4063.e6. doi: 10.1016/j.molcel.2022.09.002.
|
Structural basis of microrna biogenesis by dicer-1 and
its partner protein loqs-pb - complex iii . SNAP output
|
|
8dga
|
RNA binding protein-RNA |
cryo-EM (3.73 Å) |
Jouravleva K, Golovenko D, Demo G, Dutcher RC, Hall
TMT, Zamore PD, Korostelev AA |
(2022) "Structural
basis of microRNA biogenesis by Dicer-1 and its partner
protein Loqs-PB." Mol.Cell,
82, 4049-4063.e6. doi: 10.1016/j.molcel.2022.09.002.
|
Structural basis of microrna biogenesis by dicer-1 and
its partner protein loqs-pb - complex iv . SNAP output
|
|
8dk7
|
RNA-immune system |
X-ray (2.46 Å) |
Menichelli E, Lam BJ, Wang Y, Wang VS, Shaffer J,
Tjhung KF, Bursulaya B, Nguyen TN, Vo T, Alper PB,
McAllister CS, Jones DH, Spraggon G, Michellys PY, Joslin
J, Joyce GF, Rogers J |
(2022) "Discovery
of small molecules that target a tertiary-structured
RNA." Proc.Natl.Acad.Sci.USA,
119, e2213117119. doi: 10.1073/pnas.2213117119.
|
Crystal structure of theophylline aptamer soaked with
tal2 . SNAP output
|
|
8do6
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Paraan M, Nasef M, Chou-Zheng L, Khweis SA,
Schoeffler AJ, Hatoum-Aslan A, Stagg SM, Dunkle JA |
(2023) "The
structure of a Type III-A CRISPR-Cas effector complex
reveals conserved and idiosyncratic contacts to target
RNA and crRNA among Type III-A systems." Plos
One, 18, e0287461. doi: 10.1371/journal.pone.0287461.
|
The structure of s. epidermidis cas10-csm bound to
target RNA . SNAP
output
|
|
8dp3
|
immune system-RNA |
X-ray (1.91 Å) |
Das NK, Hollmann NM, Vogt J, Sevdalis SE, Banna HA,
Ojha M, Koirala D |
(2023) "Crystal
structure of a highly conserved enteroviral 5'
cloverleaf RNA replication element." Nat
Commun, 14, 1955. doi: 10.1038/s41467-023-37658-8.
|
Crystal structure of coxsackievirus b3 cloverleaf RNA
replication element . SNAP output
|
|
8dvr
|
hydrolase-RNA |
cryo-EM (3.3 Å) |
Wang W, Pyle AM |
(2022) "The
RIG-I receptor adopts two different conformations for
distinguishing host from viral RNA ligands."
Mol.Cell, 82, 4131. doi:
10.1016/j.molcel.2022.09.029.
|
cryo-EM structure of rig-i bound to the end of p3slr30
(+amppnp) . SNAP
output
|
|
8dvs
|
hydrolase-RNA |
cryo-EM (3.0 Å) |
Wang W, Pyle AM |
(2022) "The
RIG-I receptor adopts two different conformations for
distinguishing host from viral RNA ligands."
Mol.Cell, 82, 4131-4144.e6.
doi: 10.1016/j.molcel.2022.09.029.
|
cryo-EM structure of rig-i bound to the end of ohslr30
(+atp) . SNAP output
|
|
8dvu
|
hydrolase-RNA |
cryo-EM (2.9 Å) |
Wang W, Pyle AM |
(2022) "The
RIG-I receptor adopts two different conformations for
distinguishing host from viral RNA ligands."
Mol.Cell, 82, 4131-4144.e6.
doi: 10.1016/j.molcel.2022.09.029.
|
cryo-EM structure of rig-i bound to the internal sites
of ohslr30 (+atp) . SNAP
output
|
|
8dzk
|
hydrolase-RNA |
X-ray (2.1 Å) |
Clark NE, Katolik A, Welch A, Schorl C, Holloway SP,
Schuermann JP, Hart PJ, Taylor AB, Damha MJ, Fairbrother
WG |
(2022) "Crystal
Structure of the RNA Lariat Debranching Enzyme Dbr1
with Hydrolyzed Phosphorothioate RNA Product."
Biochemistry, 61, 2933-2939.
doi: 10.1021/acs.biochem.2c00590.
|
Dbr1 in complex with 5-mer cleavage product . SNAP output
|
|
8e0f
|
RNA binding protein-RNA |
X-ray (2.7 Å) |
Doherty EE, Karki A, Wilcox XE, Mendoza HG, Manjunath
A, Matos VJ, Fisher AJ, Beal PA |
(2022) "ADAR
activation by inducing a syn conformation at guanosine
adjacent to an editing site." Nucleic Acids
Res., 50, 10857-10868. doi:
10.1093/nar/gkac897.
|
Human adenosine deaminase acting on dsrna (adar2-rd)
bound to dsrna containing a g-g pair adjacent to the
target site . SNAP
output
|
|
8e28
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Meze K, Axhemi A, Thomas DR, Doymaz A, Joshua-Tor
L |
(2023) "A
shape-shifting nuclease unravels structured RNA."
Nat.Struct.Mol.Biol., 30,
339-347. doi: 10.1038/s41594-023-00923-x.
|
Human dis3l2 in complex with hairpin a-gcu14 . SNAP output
|
|
8e29
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Meze K, Axhemi A, Thomas DR, Doymaz A, Joshua-Tor
L |
(2023) "A
shape-shifting nuclease unravels structured RNA."
Nat.Struct.Mol.Biol., 30,
339-347. doi: 10.1038/s41594-023-00923-x.
|
Human dis3l2 in complex with hairpin c-u12 . SNAP output
|
|
8e2a
|
RNA binding protein-RNA |
cryo-EM (2.8 Å) |
Meze K, Axhemi A, Thomas DR, Doymaz A, Joshua-Tor
L |
(2023) "A
shape-shifting nuclease unravels structured RNA."
Nat.Struct.Mol.Biol., 30,
339-347. doi: 10.1038/s41594-023-00923-x.
|
Human dis3l2 in complex with hairpin d-u7 . SNAP output
|
|
8e30
|
ribosome-antibiotic |
cryo-EM (1.91 Å) |
Li Q, Pellegrino J, Lee DJ, Fraser JS, Seiple IB |
"Potential for clicked streptogramin analogs." |
E. coli 50s ribosome bound to compound streptogramin a
analog 3142 . SNAP
output
|
|
8e32
|
ribosome-antibiotic |
cryo-EM (2.35 Å) |
Takahashi Y, Pellegrino J, Lee DJ, Fraser JS, Seiple
IB |
"Potential for clicked streptogramin analogs." |
E. coli 50s ribosome bound to compound streptogramin
analogs sa1 and sb1 . SNAP output
|
|
8e33
|
ribosome-antibiotic |
cryo-EM (2.23 Å) |
Takahashi Y, Pellegrino J, Lee DJ, Fraser JS, Seiple
IB |
"Potential for clicked streptogramin analogs." |
E. coli 50s ribosome bound to compound streptogramin
analog sab001 . SNAP
output
|
|
8e35
|
ribosome-antibiotic |
cryo-EM (2.27 Å) |
Takahashi Y, Pellegrino J, Lee DJ, Fraser JS, Seiple
IB |
"Potential for clicked streptogramin analogs." |
E. coli 50s ribosome bound to compound sab002 .
SNAP output
|
|
8e36
|
ribosome-antibiotic |
cryo-EM (2.38 Å) |
Li Q, Pellegrino J, Lee DJ, Seiple IB, Fraser JS |
"Potential for clicked streptogramin analogs." |
E. coli 50s ribosome bound to compound streptogramin a
analog 3146 . SNAP
output
|
|
8e3h
|
transcription-RNA |
cryo-EM (6.5 Å) |
Molodtsov V, Wang C, Firlar E, Kaelber JT, Ebright
RH |
(2023) "Structural
basis of Rho-dependent transcription termination."
Nature, 614, 367-374. doi:
10.1038/s41586-022-05658-1.
|
Escherichia coli rho-dependent transcription
pre-termination complex containing 18 nt long RNA
spacer, mg-adp-bef3, and nusg; rho hexamer part .
SNAP output
|
|
8e3i
|
RNA binding protein |
cryo-EM (2.53 Å) |
Gutierrez PA, Wei J, Sun Y, Tong L |
(2022) "Molecular
basis for the recognition of the AUUAAA polyadenylation
signal by mPSF." Rna, 28,
1534-1541. doi: 10.1261/rna.079322.122.
|
cryo-EM structure of the human mpsf in complex with the
auuaaa poly(a) signal . SNAP output
|
|
8e3l
|
ribosome |
cryo-EM (2.35 Å) |
Boyce JH, Pellegrino J, Lee DJ, Ecker AK, Seiple IB,
Fraser JS |
"Solithromycin siderophore conjugates." |
E. coli 50s ribosome bound to d-linker solithromycin
conjugate . SNAP
output
|
|
8e3m
|
ribosome |
cryo-EM (2.25 Å) |
Boyce JH, Pellegrino J, Lee DJ, Ecker AK, Seiple IB,
Fraser JS |
"Solithromycin siderophore conjugates." |
E. coli 50s ribosome bound to l-linker solithromycin
conjugate . SNAP
output
|
|
8e3o
|
ribosome |
cryo-EM (1.99 Å) |
Boyce JH, Pellegrino J, Lee DJ, Ecker AK, Seiple IB,
Fraser JS |
"Solithromycin siderophore conjugates." |
E. coli 50s ribosome bound to solithromycin and vm1 .
SNAP output
|
|
8e40
|
viral protein-RNA |
cryo-EM (3.57 Å) |
Ito F, Alvarez-Cabrera AL, Liu S, Yang H, Shiriaeva
A, Zhou ZH, Chen XS |
(2023) "Structural
basis for HIV-1 antagonism of host APOBEC3G via Cullin
E3 ligase." Sci Adv, 9,
eade3168. doi: 10.1126/sciadv.ade3168.
|
Full-length apobec3g in complex with hiv-1 vif,
cbf-beta, and fork RNA . SNAP output
|
|
8e41
|
ribosome |
cryo-EM (2.13 Å) |
Edmonson Q, Pellegrino J, Lee DJ, Seiple IB, Fraser
JS |
"Tiamulin and NPET binders." |
E. coli 50s ribosome bound to tiamulin and vs1 .
SNAP output
|
|
8e42
|
ribosome |
cryo-EM (2.29 Å) |
Edmonson Q, Pellegrino J, Lee DJ, Seiple IB, Fraser
JS |
"Tiamulin and NPET binders." |
E. coli 50s ribosome bound to tiamulin and azithromycin
. SNAP output
|
|
8e43
|
ribosome |
cryo-EM (2.09 Å) |
Li Q, Pellegrino J, Lee DJ, Fraser JS, Seiple IB |
"Streptogramin A analogs." |
E. coli 50s ribosome bound to compound streptogramin a
analog 3336 . SNAP
output
|
|
8e44
|
ribosome |
cryo-EM (2.53 Å) |
Yeon SK, Pellegrino J, Lee DJ, Seiple IB, Fraser
JS |
"SLC collection of antibiotic analogs." |
E. coli 50s ribosome bound to antibiotic analog slc09 .
SNAP output
|
|
8e45
|
ribosome |
cryo-EM (2.3 Å) |
Yeon SK, Pellegrino J, Lee DJ, Seiple IB, Fraser
JS |
"SLC collection of antibiotic analogs." |
E. coli 50s ribosome bound to antibiotic analog slc17 .
SNAP output
|
|
8e46
|
ribosome |
cryo-EM (2.32 Å) |
Yeon SK, Pellegrino J, Lee DJ, Seiple IB, Fraser
JS |
"SLC collection of antibiotic analogs." |
E. coli 50s ribosome bound to antibiotic analog slc21 .
SNAP output
|
|
8e47
|
ribosome |
cryo-EM (2.32 Å) |
Yeon SK, Pellegrino J, Lee DJ, Seiple IB, Fraser
JS |
"SLC collection of antibiotic analogs." |
E. coli 50s ribosome bound to antibiotic analog slc26 .
SNAP output
|
|
8e48
|
ribosome |
cryo-EM (2.27 Å) |
Yeon SK, Pellegrino J, Lee DJ, Seiple IB, Fraser
JS |
"SLC collection of antibiotic analogs." |
E. coli 50s ribosome bound to antibiotic analog slc30 .
SNAP output
|
|
8e49
|
ribosome |
cryo-EM (2.05 Å) |
Yeon SK, Pellegrino J, Lee DJ, Seiple IB, Fraser
JS |
"SLC collection of antibiotic analogs." |
E. coli 50s ribosome bound to antibiotic analog slc31 .
SNAP output
|
|
8e4x
|
RNA binding protein-RNA |
X-ray (2.8 Å) |
Doherty EE, Karki A, Wilcox XE, Mendoza HG, Manjunath
A, Matos VJ, Fisher AJ, Beal PA |
(2022) "ADAR
activation by inducing a syn conformation at guanosine
adjacent to an editing site." Nucleic Acids
Res., 50, 10857-10868. doi:
10.1093/nar/gkac897.
|
Human adenosine deaminase acting on dsrna (adar2-r2d)
bound to dsrna containing a g:3-deaza da pair adjacent
to the target site . SNAP output
|
|
8e5l
|
transcription-RNA |
cryo-EM (4.2 Å) |
Molodtsov V, Wang C, Firlar E, Kaelber JT, Ebright
RH |
(2023) "Structural
basis of Rho-dependent transcription termination."
Nature, 614, 367-374. doi:
10.1038/s41586-022-05658-1.
|
Escherichia coli rho-dependent transcription
pre-termination complex containing 21 nt long RNA
spacer, mg-adp-bef3, and nusg; rho hexamer part .
SNAP output
|
|
8e5p
|
transcription-RNA |
cryo-EM (4.4 Å) |
Molodtsov V, Wang C, Firlar E, Kaelber JT, Ebright
RH |
(2023) "Structural
basis of Rho-dependent transcription termination."
Nature, 614, 367-374. doi:
10.1038/s41586-022-05658-1.
|
Escherichia coli rho-dependent transcription
pre-termination complex containing 24 nt long RNA
spacer, mg-adp-bef3, and nusg; rho hexamer part .
SNAP output
|
|
8e5t
|
ribosome |
cryo-EM (4.0 Å) |
Sanghai ZA, Piwowarczyk R, Broeck AV, Klinge S |
(2023) "A
co-transcriptional ribosome assembly checkpoint
controls nascent large ribosomal subunit
maturation." Nat.Struct.Mol.Biol.,
30, 594-599. doi: 10.1038/s41594-023-00947-3.
|
Yeast co-transcriptional noc1-noc2 rnp assembly
checkpoint intermediate . SNAP output
|
|
8e6w
|
transcription-RNA |
cryo-EM (4.27 Å) |
Molodtsov V, Wang C, Firlar E, Kaelber JT, Ebright
RH |
(2023) "Structural
basis of Rho-dependent transcription termination."
Nature, 614, 367-374. doi:
10.1038/s41586-022-05658-1.
|
Escherichia coli rho-dependent transcription
pre-termination complex containing 18 nt long RNA
spacer, lambda-tr1 rut RNA, mg-adp-bef3, and nusg; rho
part . SNAP output
|
|
8edj
|
hydrolase-RNA |
X-ray (1.83 Å) |
Yang H, Kim K, Li S, Pacheco J, Chen XS |
(2022) "Structural
basis of sequence-specific RNA recognition by the
antiviral factor APOBEC3G." Nat Commun,
13, 7498. doi: 10.1038/s41467-022-35201-9.
|
Crystal structure of ra3g-ssrna-ga . SNAP output
|
|
8eex
|
RNA binding protein-RNA |
cryo-EM (2.95 Å) |
Strecker J, Demircioglu FE, Li D, Faure G, Wilkinson
ME, Gootenberg JS, Abudayyeh OO, Nishimasu H, Macrae RK,
Zhang F |
(2022) "RNA-activated
protein cleavage with a CRISPR-associated
endopeptidase." Science,
378, 874-881. doi: 10.1126/science.add7450.
|
Cas7-11 in complex with csx29 . SNAP output
|
|
8eey
|
RNA binding protein-RNA |
cryo-EM (2.53 Å) |
Strecker J, Demircioglu FE, Li D, Faure G, Wilkinson
ME, Gootenberg JS, Abudayyeh OO, Nishimasu H, Macrae RK,
Zhang F |
(2022) "RNA-activated
protein cleavage with a CRISPR-associated
endopeptidase." Science,
378, 874-881. doi: 10.1126/science.add7450.
|
Cas7-11 in complex with dr-mismatched target RNA, csx29
and csx30 . SNAP
output
|
|
8eg0
|
transferase-RNA |
cryo-EM (3.53 Å) |
Ruiz-Arroyo VM, Raj R, Babu K, Onolbaatar O, Roberts
PH, Nam Y |
(2023) "Structures
and mechanisms of tRNA methylation by METTL1-WDR4."
Nature, 613, 383-390. doi:
10.1038/s41586-022-05565-5.
|
Cryoem structure of human mettl1-wdr4 in complex with
lys-trna and sah . SNAP
output
|
|
8eiu
|
ribosome |
cryo-EM (2.24 Å) |
Nissley AJ, Penev PI, Watson ZL, Banfield JF, Cate
JHD |
(2023) "Rare
ribosomal RNA sequences from archaea stabilize the
bacterial ribosome." Nucleic Acids Res.,
51, 1880-1894. doi: 10.1093/nar/gkac1273.
|
E. coli 70s ribosome with a-loop mutations u2554c and
u2555c . SNAP output
|
|
8ekb
|
ribosome |
X-ray (2.7 Å) |
Paranjpe MN, Marina VI, Grachev AA, Maviza TP,
Tolicheva OA, Paleskava A, Osterman IA, Sergiev PV,
Konevega AL, Polikanov YS, Gagnon MG |
(2023) "Insights
into the molecular mechanism of translation inhibition
by the ribosome-targeting antibiotic thermorubin."
Nucleic Acids Res., 51,
449-462. doi: 10.1093/nar/gkac1189.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with mrna, deacylated p-site
trnamet, and thermorubin at 2.70a resolution . SNAP output
|
|
8ekc
|
ribosome |
cryo-EM (2.7 Å) |
Paranjpe MN, Marina VI, Grachev AA, Maviza TP,
Tolicheva OA, Paleskava A, Osterman IA, Sergiev PV,
Konevega AL, Polikanov YS, Gagnon MG |
(2023) "Insights
into the molecular mechanism of translation inhibition
by the ribosome-targeting antibiotic thermorubin."
Nucleic Acids Res., 51,
449-462. doi: 10.1093/nar/gkac1189.
|
Escherichia coli 70s ribosome bound to thermorubin,
deacylated p-site trnafmet and aminoacylated a-site
phe-trna . SNAP
output
|
|
8emm
|
ribosome |
cryo-EM (2.1 Å) |
Watson ZL, Knudson IJ, Ward FR, Miller SJ, Cate JHD,
Schepartz A, Abramyan AM |
(2023) "Atomistic
simulations of the Escherichia coli ribosome provide
selection criteria for translationally active
substrates." Nat.Chem.,
15, 913-921. doi: 10.1038/s41557-023-01226-w.
|
Composite 70s ribosome structure for "atomistic
simulations of the e. coli ribosome provide selection
criteria for translationally active substrates .
SNAP output
|
|
8enk
|
RNA binding protein-RNA |
X-ray (2.5 Å) |
Xie Y, Gao S, Zhang K, Bhat P, Clarke BP, Batten K,
Mei M, Gazzara M, Shay JW, Lynch KW, Angelos AE, Hill PS,
Ivey AL, Fontoura B, Ren Y |
(2023) "Structural
basis for high-order complex of SARNP and DDX39B to
facilitate mRNP assembly." Cell Rep,
42, 112988. doi: 10.1016/j.celrep.2023.112988.
|
Crystal structure of uap56 in complex with tho1, the
yeast homolog of human sarnp . SNAP output
|
|
8epk
|
blood clotting |
X-ray (2.65 Å) |
Kolyadko VN, Layzer JM, Perry K, Sullenger BA,
Krishnaswamy S |
(2024) "An RNA
aptamer exploits exosite-dependent allostery to achieve
specific inhibition of coagulation factor IXa."
Proc.Natl.Acad.Sci.USA, 121,
e2401136121. doi: 10.1073/pnas.2401136121.
|
Complex of anticoagulant RNA aptamer and human
coagulation factor ixa (s195a) . SNAP output
|
|
8esq
|
ribosome |
cryo-EM (2.8 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Ytm1 associated nascent 60s ribosome state 2 . SNAP output
|
|
8esr
|
ribosome |
cryo-EM (3.2 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Ytm1 associated nascent 60s ribosome (-fkbp39) state 2
. SNAP output
|
|
8etc
|
ribosome |
cryo-EM (3.1 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Fkbp39 associated nascent 60s ribosome state 4 .
SNAP output
|
|
8etg
|
ribosome |
cryo-EM (3.4 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Fkbp39 associated 60s nascent ribosome state 3 .
SNAP output
|
|
8eth
|
ribosome |
cryo-EM (3.8 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Ytm1 associated 60s nascent ribosome state 1b .
SNAP output
|
|
8eti
|
ribosome |
cryo-EM (3.7 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Fkbp39 associated 60s nascent ribosome state 1 .
SNAP output
|
|
8etj
|
ribosome |
cryo-EM (3.2 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Fkbp39 associated 60s nascent ribosome state 2 .
SNAP output
|
|
8eug
|
ribosome |
cryo-EM (2.8 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Ytm1 associated nascent 60s ribosome state 3 . SNAP output
|
|
8eui
|
ribosome |
cryo-EM (3.1 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Ytm1 associated nascent 60s ribosome (-fkbp39) state 3
. SNAP output
|
|
8eup
|
ribosome |
cryo-EM (3.1 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Ytm1 associated 60s nascent ribosome state 1a .
SNAP output
|
|
8euy
|
ribosome |
cryo-EM (3.0 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Ytm1 associated nascent 60s ribosome (-fkbp39) state 1a
. SNAP output
|
|
8ev3
|
ribosome |
cryo-EM (3.0 Å) |
Ugolini I, Bilokapic S, Ferrolino M, Teague J, Yan Y,
Zhou X, Deshmukh A, White M, Kriwacki RW, Halic M |
(2022) "Chromatin
localization of nucleophosmin organizes ribosome
biogenesis." Mol.Cell,
82, 4443. doi: 10.1016/j.molcel.2022.10.033.
|
Ytm1 associated 60s nascent ribosome (-fkbp39) state 1b
. SNAP output
|
|
8ev6
|
ribosome |
X-ray (2.946 Å) |
Seely SM, Parajuli NP, De Tarafder A, Ge X, Sanyal S,
Gagnon MG |
(2023) "Molecular
basis of the pleiotropic effects by the antibiotic
amikacin on the ribosome." Nat Commun,
14, 4666. doi: 10.1038/s41467-023-40416-5.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with amikacin, mrna, and a-, p-,
and e-site trnas . SNAP
output
|
|
8ev7
|
ribosome |
X-ray (2.89 Å) |
Seely SM, Parajuli NP, De Tarafder A, Ge X, Sanyal S,
Gagnon MG |
(2023) "Molecular
basis of the pleiotropic effects by the antibiotic
amikacin on the ribosome." Nat Commun,
14, 4666. doi: 10.1038/s41467-023-40416-5.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with kanamycin, mrna, and a-, p-,
and e-site trnas . SNAP
output
|
|
8evp
|
ribosome |
cryo-EM (2.38 Å) |
Zhao Y, Rai J, Li H |
(2023) "Regulation
of translation by ribosomal RNA pseudouridylation."
Sci Adv, 9, eadg8190. doi:
10.1126/sciadv.adg8190.
|
Hypopseudouridylated yeast 80s bound with taura
syndrome virus (tsv) internal ribosome entry site
(ires), structure i . SNAP output
|
|
8evt
|
ribosome-RNA |
cryo-EM (2.2 Å) |
Zhao Y, Rai J, Li H |
(2023) "Regulation
of translation by ribosomal RNA pseudouridylation."
Sci Adv, 9, eadg8190. doi:
10.1126/sciadv.adg8190.
|
Hypopseudouridylated yeast 80s bound with taura
syndrome virus (tsv) internal ribosome entry site
(ires) refined against a composite map . SNAP output
|
|
8ewb
|
ribosome |
cryo-EM (2.87 Å) |
Zhao Y, Rai J, Li H |
(2023) "Regulation
of translation by ribosomal RNA pseudouridylation."
Sci Adv, 9, eadg8190. doi:
10.1126/sciadv.adg8190.
|
Hypopseudouridylated yeast 80s bound with taura
syndrome virus (tsv) internal ribosome entry site
(ires), eef2 and gdp, structure iii . SNAP output
|
|
8ewc
|
ribosome |
cryo-EM (2.45 Å) |
Zhao Y, Rai J, Li H |
(2023) "Regulation
of translation by ribosomal RNA pseudouridylation."
Sci Adv, 9, eadg8190. doi:
10.1126/sciadv.adg8190.
|
Hypopseudouridylated yeast 80s bound with taura
syndrome virus (tsv) internal ribosome entry site
(ires), structure ii . SNAP output
|
|
8ewg
|
hydrolase-RNA |
cryo-EM (2.9 Å) |
Wang F, Zhang C, Xu H, Zeng W, Ma L, Li Z |
(2023) "Structural
Basis for the Ribonuclease Activity of a Thermostable
CRISPR-Cas13a from Thermoclostridium caenicola."
J.Mol.Biol., 435, 168197.
doi: 10.1016/j.jmb.2023.168197.
|
cryo-EM structure of a riboendonclease . SNAP output
|
|
8ey6
|
RNA binding protein-RNA |
X-ray (1.63 Å) |
Kozlov G, Jiang J, Rutherford T, Noronha AM, Wilds
CJ, Gehring K |
(2024) "Enhanced
binding of guanylated poly(A) RNA by the LaM domain of
LARP1." Rna Biol., 21,
7-16. doi: 10.1080/15476286.2024.2379121.
|
Lam domain of human larp1 in complex with aaaaag RNA .
SNAP output
|
|
8ey7
|
RNA binding protein-RNA |
X-ray (1.35 Å) |
Kozlov G, Jiang J, Rutherford T, Noronha AM, Wilds
CJ, Gehring K |
(2024) "Enhanced
binding of guanylated poly(A) RNA by the LaM domain of
LARP1." Rna Biol., 21,
7-16. doi: 10.1080/15476286.2024.2379121.
|
Lam domain of human larp1 in complex with aaagaa RNA .
SNAP output
|
|
8ey8
|
RNA binding protein-RNA |
X-ray (1.3 Å) |
Kozlov G, Jiang J, Rutherford T, Noronha AM, Wilds
CJ, Gehring K |
(2024) "Enhanced
binding of guanylated poly(A) RNA by the LaM domain of
LARP1." Rna Biol., 21,
7-16. doi: 10.1080/15476286.2024.2379121.
|
Lam domain of human larp1 in complex with aaaaga RNA .
SNAP output
|
|
8eyq
|
ribosome |
cryo-EM (3.3 Å) |
Sun J, Kinman LF, Jahagirdar D, Ortega J, Davis
JH |
(2023) "KsgA
facilitates ribosomal small subunit maturation by
proofreading a key structural lesion."
Nat.Struct.Mol.Biol., 30,
1468-1480. doi: 10.1038/s41594-023-01078-5.
|
30s_delta_ksga_h44_inactive_conformation . SNAP output
|
|
8eyt
|
ribosome |
cryo-EM (2.8 Å) |
Sun J, Kinman LF, Jahagirdar D, Ortega J, Davis
JH |
(2023) "KsgA
facilitates ribosomal small subunit maturation by
proofreading a key structural lesion."
Nat.Struct.Mol.Biol., 30,
1468-1480. doi: 10.1038/s41594-023-01078-5.
|
30s_delta_ksga+ksga complex . SNAP output
|
|
8f5g
|
RNA binding protein-RNA |
X-ray (2.7 Å) |
Elghondakly A, Jermain MD, Winkler WC, Ferre-D'Amare
AR |
(2024) "Major-groove
sequence-specific RNA recognition by LoaP, a paralog of
transcription elongation factor NusG."
Structure, 32, 1488. doi:
10.1016/j.str.2024.06.001.
|
Nusg-RNA complex . SNAP
output
|
|
8fc1
|
ribosome |
X-ray (2.5 Å) |
Chen CW, Leimer N, Syroegin EA, Dunand C, Bulman ZP,
Lewis K, Polikanov YS, Svetlov MS |
(2023) "Structural
insights into the mechanism of overcoming Erm-mediated
resistance by macrolides acting together with
hygromycin-A." Nat Commun,
14, 4196. doi: 10.1038/s41467-023-39653-5.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, hygromycin a, and
erythromycin at 2.50a resolution . SNAP output
|
|
8fc2
|
ribosome |
X-ray (2.5 Å) |
Chen CW, Leimer N, Syroegin EA, Dunand C, Bulman ZP,
Lewis K, Polikanov YS, Svetlov MS |
(2023) "Structural
insights into the mechanism of overcoming Erm-mediated
resistance by macrolides acting together with
hygromycin-A." Nat Commun,
14, 4196. doi: 10.1038/s41467-023-39653-5.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, hygromycin a, and
azithromycin at 2.50a resolution . SNAP output
|
|
8fc3
|
ribosome |
X-ray (2.6 Å) |
Chen CW, Leimer N, Syroegin EA, Dunand C, Bulman ZP,
Lewis K, Polikanov YS, Svetlov MS |
(2023) "Structural
insights into the mechanism of overcoming Erm-mediated
resistance by macrolides acting together with
hygromycin-A." Nat Commun,
14, 4196. doi: 10.1038/s41467-023-39653-5.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, hygromycin a, and
telithromycin at 2.60a resolution . SNAP output
|
|
8fc4
|
ribosome |
X-ray (2.45 Å) |
Chen CW, Leimer N, Syroegin EA, Dunand C, Bulman ZP,
Lewis K, Polikanov YS, Svetlov MS |
(2023) "Structural
insights into the mechanism of overcoming Erm-mediated
resistance by macrolides acting together with
hygromycin-A." Nat Commun,
14, 4196. doi: 10.1038/s41467-023-39653-5.
|
Crystal structure of the a2058-n6-dimethylated thermus
thermophilus 70s ribosome in complex with protein y,
hygromycin a, and erythromycin at 2.45a resolution .
SNAP output
|
|
8fc5
|
ribosome |
X-ray (2.65 Å) |
Chen CW, Leimer N, Syroegin EA, Dunand C, Bulman ZP,
Lewis K, Polikanov YS, Svetlov MS |
(2023) "Structural
insights into the mechanism of overcoming Erm-mediated
resistance by macrolides acting together with
hygromycin-A." Nat Commun,
14, 4196. doi: 10.1038/s41467-023-39653-5.
|
Crystal structure of the a2058-n6-dimethylated thermus
thermophilus 70s ribosome in complex with protein y,
hygromycin a, and azithromycin at 2.65a resolution .
SNAP output
|
|
8fc6
|
ribosome |
X-ray (2.35 Å) |
Chen CW, Leimer N, Syroegin EA, Dunand C, Bulman ZP,
Lewis K, Polikanov YS, Svetlov MS |
(2023) "Structural
insights into the mechanism of overcoming Erm-mediated
resistance by macrolides acting together with
hygromycin-A." Nat Commun,
14, 4196. doi: 10.1038/s41467-023-39653-5.
|
Crystal structure of the a2058-n6-dimethylated thermus
thermophilus 70s ribosome in complex with protein y,
hygromycin a, and telithromycin at 2.35a resolution .
SNAP output
|
|
8fd2
|
DNA binding protein |
cryo-EM (3.65 Å) |
Wang S, Gabel C, Siddique R, Klose T, Chang L |
(2023) "Molecular
mechanism for Tn7-like transposon recruitment by a type
I-B CRISPR effector." Cell,
186, 4204-4215.e19. doi: 10.1016/j.cell.2023.07.010.
|
cryo-EM structure of cascade complex in type i-b cast
system . SNAP output
|
|
8ffr
|
viral protein |
X-ray (3.49 Å) |
Gerard FCA, Bourhis JM, Mas C, Branchard A, Vu DD,
Varhoshkova S, Leyrat C, Jamin M |
(2022) "Structure
and Dynamics of the Unassembled Nucleoprotein of Rabies
Virus in Complex with Its Phosphoprotein Chaperone
Module." Viruses, 14.
doi: 10.3390/v14122813.
|
Revised structure of the rabies virus nucleoprotein-RNA
complex . SNAP
output
|
|
8ffy
|
ligase-RNA |
cryo-EM (3.6 Å) |
Kuhle B, Hirschi M, Doerfel LK, Lander GC, Schimmel
P |
(2023) "Structural
basis for a degenerate tRNA identity code and the
evolution of bimodal specificity in human mitochondrial
tRNA recognition." Nat Commun,
14, 4794. doi: 10.1038/s41467-023-40354-2.
|
Cryo-electron microscopy structure of human mt-serrs in
complex with mt-trna(uga-tl) . SNAP output
|
|
8fiz
|
translation |
cryo-EM (3.8 Å) |
Wee LM, Tong AB, Florez Ariza AJ, Canari-Chumpitaz C,
Grob P, Nogales E, Bustamante CJ |
(2023) "A
trailing ribosome speeds up RNA polymerase at the
expense of transcript fidelity via force and
allostery." Cell, 186,
1244-1262.e34. doi: 10.1016/j.cell.2023.02.008.
|
cryo-EM structure of e. coli 70s ribosome containing
mrna and trna (in the transcription-translation
complex) . SNAP
output
|
|
8fjk
|
virus |
cryo-EM (3.3 Å) |
Stevens A, Cui Y, Shivakoti S, Zhou ZH |
(2023) "Asymmetric
reconstruction of the aquareovirus core at near-atomic
resolution and mechanism of transcription
initiation." Protein Cell,
14, 544-548. doi: 10.1093/procel/pwad002.
|
Golden shiner reovirus core polar vertex . SNAP output
|
|
8fjl
|
virus |
cryo-EM (3.27 Å) |
Stevens A, Cui Y, Shivakoti S, Zhou ZH |
(2023) "Asymmetric
reconstruction of the aquareovirus core at near-atomic
resolution and mechanism of transcription
initiation." Protein Cell,
14, 544-548. doi: 10.1093/procel/pwad002.
|
Golden shiner reovirus core tropical vertex . SNAP output
|
|
8fkp
|
ribosome |
cryo-EM (2.85 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state a1) .
SNAP output
|
|
8fkq
|
ribosome |
cryo-EM (2.76 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state a2) .
SNAP output
|
|
8fkr
|
ribosome |
cryo-EM (2.89 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state b1) .
SNAP output
|
|
8fks
|
ribosome |
cryo-EM (2.88 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state b2) .
SNAP output
|
|
8fkt
|
ribosome |
cryo-EM (2.81 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state c1) .
SNAP output
|
|
8fku
|
ribosome |
cryo-EM (2.82 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state c2) .
SNAP output
|
|
8fkv
|
ribosome |
cryo-EM (2.47 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state d1) .
SNAP output
|
|
8fkw
|
ribosome |
cryo-EM (2.5 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state d2) .
SNAP output
|
|
8fkx
|
ribosome |
cryo-EM (2.59 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state e) .
SNAP output
|
|
8fky
|
ribosome |
cryo-EM (2.67 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state f) .
SNAP output
|
|
8fkz
|
ribosome |
cryo-EM (3.04 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state g) .
SNAP output
|
|
8fl0
|
ribosome |
cryo-EM (2.91 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nucleolar pre-60s ribosomal subunit (state h) .
SNAP output
|
|
8fl2
|
ribosome |
cryo-EM (2.67 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state i1) .
SNAP output
|
|
8fl3
|
ribosome |
cryo-EM (2.53 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state i2) .
SNAP output
|
|
8fl4
|
ribosome |
cryo-EM (2.89 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state i3) .
SNAP output
|
|
8fl6
|
ribosome |
cryo-EM (2.62 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state j1) .
SNAP output
|
|
8fl7
|
ribosome |
cryo-EM (2.55 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state j2) .
SNAP output
|
|
8fl9
|
ribosome |
cryo-EM (2.75 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state j3) .
SNAP output
|
|
8fla
|
ribosome |
cryo-EM (2.63 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state k1) .
SNAP output
|
|
8flb
|
ribosome |
cryo-EM (2.55 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state k2) .
SNAP output
|
|
8flc
|
ribosome |
cryo-EM (2.76 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state k3) .
SNAP output
|
|
8fld
|
ribosome |
cryo-EM (2.58 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state l1) .
SNAP output
|
|
8fle
|
ribosome |
cryo-EM (2.48 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state l2) .
SNAP output
|
|
8flf
|
ribosome |
cryo-EM (2.65 Å) |
Vanden Broeck A, Klinge S |
(2023) "Principles
of human pre-60 S biogenesis." Science,
381, eadh3892. doi: 10.1126/science.adh3892.
|
Human nuclear pre-60s ribosomal subunit (state l3) .
SNAP output
|
|
8fli
|
splicing-RNA |
cryo-EM (3.8 Å) |
Haack DB, Rudolfs B, Zhang C, Lyumkis D, Toor N |
(2024) "Structural
basis of branching during RNA splicing."
Nat.Struct.Mol.Biol., 31,
179-189. doi: 10.1038/s41594-023-01150-0.
|
cryo-EM structure of a group ii intron immediately
before branching . SNAP
output
|
|
8fmw
|
ribosome |
cryo-EM (2.86 Å) |
Sharma MR, Manjari SR, Agrawal EK, Keshavan P,
Koripella RK, Majumdar S, Marcinkiewicz AL, Lin YP,
Agrawal RK, Banavali NK |
(2023) "The
structure of a hibernating ribosome in a Lyme disease
pathogen." Nat Commun,
14, 6961. doi: 10.1038/s41467-023-42266-7.
|
The structure of a hibernating ribosome in the lyme
disease pathogen . SNAP
output
|
|
8fn2
|
ribosome |
cryo-EM (3.4 Å) |
Sharma MR, Manjari SR, Agrawal EK, Keshavan P,
Koripella RK, Majumdar S, Marcinkiewicz AL, Lin YP,
Agrawal RK, Banavali NK |
(2023) "The
structure of a hibernating ribosome in a Lyme disease
pathogen." Nat Commun,
14, 6961. doi: 10.1038/s41467-023-42266-7.
|
The structure of a 50s ribosomal subunit in the lyme
disease pathogen borreliella burgdorferi . SNAP output
|
|
8fn6
|
RNA binding protein-RNA |
cryo-EM (3.7 Å) |
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu
JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang
L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH |
(2023) "Structural
basis of gRNA stabilization and mRNA recognition in
trypanosomal RNA editing." Science,
381, eadg4725. doi: 10.1126/science.adg4725.
|
cryo-EM structure of rnase-untreated resc-a in
trypanosomal RNA editing . SNAP output
|
|
8fnc
|
RNA binding protein-RNA |
cryo-EM (3.3 Å) |
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu
JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang
L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH |
(2023) "Structural
basis of gRNA stabilization and mRNA recognition in
trypanosomal RNA editing." Science,
381, eadg4725. doi: 10.1126/science.adg4725.
|
cryo-EM structure of rnase-treated resc-c in
trypanosomal RNA editing . SNAP output
|
|
8fnf
|
RNA binding protein-RNA |
cryo-EM (3.5 Å) |
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu
JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang
L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH |
(2023) "Structural
basis of gRNA stabilization and mRNA recognition in
trypanosomal RNA editing." Science,
381, eadg4725. doi: 10.1126/science.adg4725.
|
cryo-EM structure of rnase-untreated resc-c in
trypanosomal RNA editing . SNAP output
|
|
8fni
|
RNA binding protein-RNA |
cryo-EM (3.4 Å) |
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu
JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang
L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH |
(2023) "Structural
basis of gRNA stabilization and mRNA recognition in
trypanosomal RNA editing." Science,
381, eadg4725. doi: 10.1126/science.adg4725.
|
cryo-EM structure of rnase-treated resc-b in
trypanosomal RNA editing . SNAP output
|
|
8fnk
|
RNA binding protein-RNA |
cryo-EM (3.7 Å) |
Liu S, Wang H, Li X, Zhang F, Lee JKJ, Li Z, Yu C, Hu
JJ, Zhao X, Suematsu T, Alvarez-Cabrera AL, Liu Q, Zhang
L, Huang L, Aphasizheva I, Aphasizhev R, Zhou ZH |
(2023) "Structural
basis of gRNA stabilization and mRNA recognition in
trypanosomal RNA editing." Science,
381, eadg4725. doi: 10.1126/science.adg4725.
|
cryo-EM structure of rnase-untreated resc-b in
trypanosomal RNA editing . SNAP output
|
|
8fom
|
ribosome |
X-ray (3.58 Å) |
Nguyen HA, Hoffer ED, Fagan CE, Maehigashi T, Dunham
CM |
(2023) "Structural
basis for reduced ribosomal A-site fidelity in response
to P-site codon-anticodon mismatches."
J.Biol.Chem., 299, 104608.
doi: 10.1016/j.jbc.2023.104608.
|
Crystal structure of trna^lys(suu) bound to uaa codon
in the ribosomal p site . SNAP output
|
|
8fon
|
ribosome |
X-ray (3.64 Å) |
Nguyen HA, Hoffer ED, Fagan CE, Maehigashi T, Dunham
CM |
(2023) "Structural
basis for reduced ribosomal A-site fidelity in response
to P-site codon-anticodon mismatches."
J.Biol.Chem., 299, 104608.
doi: 10.1016/j.jbc.2023.104608.
|
Crystal structure of trna^lys(suu) bound to aua codon
in the ribosomal p site . SNAP output
|
|
8fr8
|
translation |
cryo-EM (2.76 Å) |
Li Y, Majumdar S, Treen R, Sharma MR, Corro J, Gamper
HB, Manjari SR, Prusa J, Banavali NK, Stallings CL, Hou
YM, Agrawal RK, Ojha AK |
(2023) "Starvation
sensing by mycobacterial RelA/SpoT homologue through
constitutive surveillance of translation."
Proc.Natl.Acad.Sci.USA, 120,
e2302006120. doi: 10.1073/pnas.2302006120.
|
Structure of mycobacterium smegmatis rsh bound to a 70s
translation initiation complex . SNAP output
|
|
8fru
|
ribosome |
cryo-EM (2.49 Å) |
Eiler DR, Wimberly BT, Bilodeau DY, Taliaferro JM,
Reigan P, Rissland OS, Kieft JS |
(2024) "The
Giardia lamblia ribosome structure reveals divergence
in several biological pathways and the mode of emetine
function." Structure, 32,
400. doi: 10.1016/j.str.2023.12.015.
|
60s subunit of the giardia lamblia 80s ribosome .
SNAP output
|
|
8fti
|
RNA binding protein-RNA |
cryo-EM (3.5 Å) |
Deng X, Osikpa E, Yang J, Oladeji SJ, Smith J, Gao X,
Gao Y |
(2023) "Structural
basis for the activation of a compact CRISPR-Cas13
nuclease." Nat Commun,
14, 5845. doi: 10.1038/s41467-023-41501-5.
|
cryo-EM structure of the cas13bt3-crrna-target RNA
ternary complex in activated state . SNAP output
|
|
8fto
|
ribosome |
cryo-EM (1.85 Å) |
Nissley AJ, Kamal TS, Cate JHD |
(2023) "Interactions
between terminal ribosomal RNA helices stabilize the E.
coli large ribosomal subunit." Rna,
29, 1500-1508. doi: 10.1261/rna.079690.123.
|
E. coli 70s ribosome with an improved ms2 tag inserted
in h98 . SNAP output
|
|
8fuk
|
antiviral protein-RNA |
cryo-EM (3.36 Å) |
Chou CW, Finkelstein IJ, Hu K |
"V. cholerae TniQ-Cascade complex with Type III-B
crRNA." |
V. cholerae tniq-cascade complex with type iii-b crrna
. SNAP output
|
|
8fvi
|
antiviral protein |
cryo-EM (3.24 Å) |
Ito F, Alvarez-Cabrera AL, Kim K, Zhou ZH, Chen
XS |
(2023) "Structural
basis of HIV-1 Vif-mediated E3 ligase targeting of host
APOBEC3H." Nat Commun,
14, 5241. doi: 10.1038/s41467-023-40955-x.
|
Human apobec3h bound to hiv-1 vif in complex with
cbf-beta, elob, eloc, and cul5 . SNAP output
|
|
8fvy
|
ribosome |
cryo-EM (2.94 Å) |
Eiler DR, Wimberly BT, Bilodeau DY, Taliaferro JM,
Reigan P, Rissland OS, Kieft JS |
(2024) "The
Giardia lamblia ribosome structure reveals divergence
in several biological pathways and the mode of emetine
function." Structure, 32,
400. doi: 10.1016/j.str.2023.12.015.
|
40s subunit of the giardia lamblia 80s ribosome .
SNAP output
|
|
8fyh
|
gene regulation |
cryo-EM (3.4 Å) |
Song J, Gooding AR, Hemphill WO, Love BD, Robertson
A, Yao L, Zon LI, North TE, Kasinath V, Cech TR |
(2023) "Structural
basis for inactivation of PRC2 by G-quadruplex
RNA." Science, 381,
1331-1337. doi: 10.1126/science.adh0059.
|
G4 RNA-mediated prc2 dimer . SNAP output
|
|
8fzd
|
ribosome |
cryo-EM (3.1 Å) |
Li L, Rybak MY, Lin J, Gagnon MG |
(2024) "The
ribosome termination complex remodels release factor
RF3 and ejects GDP." Nat.Struct.Mol.Biol.,
31, 1909-1920. doi: 10.1038/s41594-024-01360-0.
|
cryo-EM structure of an e. coli non-rotated ribosome
termination complex bound with aporf3, rf1, p- and
e-site trnaphe (composite state i-b) . SNAP output
|
|
8fze
|
ribosome |
cryo-EM (3.0 Å) |
Li L, Rybak MY, Lin J, Gagnon MG |
(2024) "The
ribosome termination complex remodels release factor
RF3 and ejects GDP." Nat.Struct.Mol.Biol.,
31, 1909-1920. doi: 10.1038/s41594-024-01360-0.
|
cryo-EM structure of an e. coli non-rotated ribosome
termination complex bound with rf1, p- and e-site
trnaphe (state i-a) . SNAP output
|
|
8fzf
|
ribosome-RNA |
cryo-EM (3.2 Å) |
Li L, Rybak MY, Lin J, Gagnon MG |
(2024) "The
ribosome termination complex remodels release factor
RF3 and ejects GDP." Nat.Struct.Mol.Biol.,
31, 1909-1920. doi: 10.1038/s41594-024-01360-0.
|
cryo-EM structure of an e. coli rotated ribosome
complex bound with rf3-ppgpp and p-e-trnaphe (composite
state i-c) . SNAP
output
|
|
8fzg
|
ribosome |
cryo-EM (3.1 Å) |
Li L, Rybak MY, Lin J, Gagnon MG |
(2024) "The
ribosome termination complex remodels release factor
RF3 and ejects GDP." Nat.Struct.Mol.Biol.,
31, 1909-1920. doi: 10.1038/s41594-024-01360-0.
|
cryo-EM structure of an e. coli non-rotated ribosome
termination complex bound with rf3-gdpcp, rf1, p- and
e-site trnaphe (composite state ii-a) . SNAP output
|
|
8fzh
|
ribosome |
cryo-EM (2.9 Å) |
Li L, Rybak MY, Lin J, Gagnon MG |
(2024) "The
ribosome termination complex remodels release factor
RF3 and ejects GDP." Nat.Struct.Mol.Biol.,
31, 1909-1920. doi: 10.1038/s41594-024-01360-0.
|
cryo-EM structure of an e. coli non-rotated ribosome
termination complex bound with rf1, p- and e-site
trnaphe (state ii-d) . SNAP output
|
|
8fzi
|
ribosome |
cryo-EM (3.1 Å) |
Li L, Rybak MY, Lin J, Gagnon MG |
(2024) "The
ribosome termination complex remodels release factor
RF3 and ejects GDP." Nat.Struct.Mol.Biol.,
31, 1909-1920. doi: 10.1038/s41594-024-01360-0.
|
cryo-EM structure of an e. coli rotated ribosome bound
with rf3-gdpcp and p-e-trnaphe (composite state ii-b) .
SNAP output
|
|
8fzj
|
ribosome |
cryo-EM (3.0 Å) |
Li L, Rybak MY, Lin J, Gagnon MG |
(2024) "The
ribosome termination complex remodels release factor
RF3 and ejects GDP." Nat.Struct.Mol.Biol.,
31, 1909-1920. doi: 10.1038/s41594-024-01360-0.
|
cryo-EM structure of an e. coli rotated ribosome bound
with rf3-gdpcp and p-e-trnaphe (composite state ii-c) .
SNAP output
|
|
8fzr
|
transferase-RNA |
cryo-EM (3.6 Å) |
Abeywansha T, Huang W, Ye X, Nawrocki A, Lan X,
Jankowsky E, Taylor DJ, Zhang Y |
(2023) "The
structural basis of tRNA recognition by
arginyl-tRNA-protein transferase." Nat
Commun, 14, 2232. doi: 10.1038/s41467-023-38004-8.
|
Cryoem structure of yeast arginyltransferase 1 (ate1) .
SNAP output
|
|
8g29
|
ribosome |
X-ray (2.55 Å) |
Aleksandrova EV, Wu KJY, Tresco BIC, Syroegin EA,
Killeavy EE, Balasanyants SM, Svetlov MS, Gregory ST,
Atkinson GC, Myers AG, Polikanov YS |
(2024) "Structural
basis of Cfr-mediated antimicrobial resistance and
mechanisms to evade it." Nat.Chem.Biol.,
20, 867-876. doi: 10.1038/s41589-023-01525-w.
|
Crystal structure of the a2503-c2,c8-dimethylated
thermus thermophilus 70s ribosome in complex with mrna,
aminoacylated a-site phe-trnaphe, aminoacylated p-site
fmet-trnamet, and deacylated e-site trnaphe at 2.55a
resolution . SNAP
output
|
|
8g2a
|
ribosome |
X-ray (2.45 Å) |
Aleksandrova EV, Wu KJY, Tresco BIC, Syroegin EA,
Killeavy EE, Balasanyants SM, Svetlov MS, Gregory ST,
Atkinson GC, Myers AG, Polikanov YS |
(2024) "Structural
basis of Cfr-mediated antimicrobial resistance and
mechanisms to evade it." Nat.Chem.Biol.,
20, 867-876. doi: 10.1038/s41589-023-01525-w.
|
Crystal structure of the a2503-c2,c8-dimethylated
thermus thermophilus 70s ribosome in complex with mrna,
aminoacylated a-site phe-trnaphe, peptidyl p-site
fmthsmrc-trnamet, and deacylated e-site trnaphe at
2.45a resolution . SNAP
output
|
|
8g2b
|
ribosome |
X-ray (2.55 Å) |
Aleksandrova EV, Wu KJY, Tresco BIC, Syroegin EA,
Killeavy EE, Balasanyants SM, Svetlov MS, Gregory ST,
Atkinson GC, Myers AG, Polikanov YS |
(2024) "Structural
basis of Cfr-mediated antimicrobial resistance and
mechanisms to evade it." Nat.Chem.Biol.,
20, 867-876. doi: 10.1038/s41589-023-01525-w.
|
Crystal structure of the a2503-c2,c8-dimethylated
thermus thermophilus 70s ribosome in complex with
iboxamycin, mrna, deacylated a- and e-site trnaphe, and
aminoacylated p-site fmet-trnamet at 2.55a resolution .
SNAP output
|
|
8g2c
|
ribosome |
X-ray (2.65 Å) |
Aleksandrova EV, Wu KJY, Tresco BIC, Syroegin EA,
Killeavy EE, Balasanyants SM, Svetlov MS, Gregory ST,
Atkinson GC, Myers AG, Polikanov YS |
(2024) "Structural
basis of Cfr-mediated antimicrobial resistance and
mechanisms to evade it." Nat.Chem.Biol.,
20, 867-876. doi: 10.1038/s41589-023-01525-w.
|
Crystal structure of the a2503-c2,c8-dimethylated
thermus thermophilus 70s ribosome in complex with
tylosin, mrna, aminoacylated a-site phe-trnaphe,
aminoacylated p-site fmet-trnamet, and deacylated
e-site trnaphe at 2.65a resolution . SNAP output
|
|
8g2d
|
ribosome |
X-ray (2.7 Å) |
Aleksandrova EV, Wu KJY, Tresco BIC, Syroegin EA,
Killeavy EE, Balasanyants SM, Svetlov MS, Gregory ST,
Atkinson GC, Myers AG, Polikanov YS |
(2024) "Structural
basis of Cfr-mediated antimicrobial resistance and
mechanisms to evade it." Nat.Chem.Biol.,
20, 867-876. doi: 10.1038/s41589-023-01525-w.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with tylosin, mrna, deacylated
a- and e-site trnaphe, and deacylated p-site trnamet at
2.70a resolution . SNAP
output
|
|
8g2u
|
ribosome |
cryo-EM (3.0 Å) |
Bhattacharjee S, Feng X, Maji S, Dadhwal P, Zhang Z,
Brown ZP, Frank J |
(2024) "Time
resolution in cryo-EM using a PDMS-based microfluidic
chip assembly and its application to the study of
HflX-mediated ribosome recycling." Cell,
187, 782-796.e23. doi: 10.1016/j.cell.2023.12.027.
|
Time-resolved cryo-EM study of the 70s recycling by the
hflx:control-apo-70s at 900ms . SNAP output
|
|
8g31
|
ribosome |
cryo-EM (3.2 Å) |
Bhattacharjee S, Feng X, Maji S, Dadhwal P, Zhang Z,
Brown ZP, Frank J |
(2024) "Time
resolution in cryo-EM using a PDMS-based microfluidic
chip assembly and its application to the study of
HflX-mediated ribosome recycling." Cell,
187, 782-796.e23. doi: 10.1016/j.cell.2023.12.027.
|
Time-resolved cryo-EM study of the 70s recycling by the
hflx:2nd intermediate . SNAP output
|
|
8g34
|
ribosome |
cryo-EM (3.2 Å) |
Bhattacharjee S, Feng X, Maji S, Dadhwal P, Zhang Z,
Brown ZP, Frank J |
(2024) "Time
resolution in cryo-EM using a PDMS-based microfluidic
chip assembly and its application to the study of
HflX-mediated ribosome recycling." Cell,
187, 782-796.e23. doi: 10.1016/j.cell.2023.12.027.
|
Time-resolved cryo-EM study of the 70s recycling by the
hflx:1st intermediate . SNAP output
|
|
8g38
|
ribosome |
cryo-EM (3.2 Å) |
Bhattacharjee S, Feng X, Maji S, Dadhwal P, Zhang Z,
Brown ZP, Frank J |
(2024) "Time
resolution in cryo-EM using a PDMS-based microfluidic
chip assembly and its application to the study of
HflX-mediated ribosome recycling." Cell,
187, 782-796.e23. doi: 10.1016/j.cell.2023.12.027.
|
Time-resolved cryo-EM study of the 70s recycling by the
hflx:3rd intermediate . SNAP output
|
|
8g4i
|
ribosome |
cryo-EM (3.24 Å) |
Eiler DR, Wimberly BT, Bilodeau DY, Taliaferro JM,
Reigan P, Rissland OS, Kieft JS |
(2024) "The
Giardia lamblia ribosome structure reveals divergence
in several biological pathways and the mode of emetine
function." Structure, 32,
400-410.e4. doi: 10.1016/j.str.2023.12.015.
|
40s ribosomal subunit of the 80s giardia intestinalis
assemblage a ribosome with emetine bound in v1
conformation . SNAP
output
|
|
8g4s
|
ribosome |
cryo-EM (3.14 Å) |
Eiler DR, Wimberly BT, Bilodeau DY, Taliaferro JM,
Reigan P, Rissland OS, Kieft JS |
(2024) "The
Giardia lamblia ribosome structure reveals divergence
in several biological pathways and the mode of emetine
function." Structure, 32,
400. doi: 10.1016/j.str.2023.12.015.
|
40s ribosomal subunit of the 80s giardia intestinalis
assemblage a ribosome with emetine bound in v2
conformation with mrna and three trnas. . SNAP output
|
|
8g5z
|
ribosome |
cryo-EM (2.64 Å) |
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson
ZL, Altman RB, Wang HY, Taunton J, Blanchard SC |
(2023) "mRNA
decoding in human is kinetically and structurally
distinct from bacteria." Nature,
617, 200-207. doi: 10.1038/s41586-023-05908-w.
|
Mrna decoding in human is kinetically and structurally
distinct from bacteria (ga state) . SNAP output
|
|
8g60
|
ribosome |
cryo-EM (2.54 Å) |
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson
ZL, Altman RB, Wang HY, Taunton J, Blanchard SC |
(2023) "mRNA
decoding in human is kinetically and structurally
distinct from bacteria." Nature,
617, 200-207. doi: 10.1038/s41586-023-05908-w.
|
Mrna decoding in human is kinetically and structurally
distinct from bacteria (cr state) . SNAP output
|
|
8g61
|
ribosome |
cryo-EM (2.94 Å) |
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson
ZL, Altman RB, Wang HY, Taunton J, Blanchard SC |
(2023) "mRNA
decoding in human is kinetically and structurally
distinct from bacteria." Nature,
617, 200-207. doi: 10.1038/s41586-023-05908-w.
|
Mrna decoding in human is kinetically and structurally
distinct from bacteria (ac state) . SNAP output
|
|
8g6j
|
ribosome |
cryo-EM (2.8 Å) |
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson
ZL, Altman RB, Wang HY, Taunton J, Blanchard SC |
(2023) "mRNA
decoding in human is kinetically and structurally
distinct from bacteria." Nature,
617, 200-207. doi: 10.1038/s41586-023-05908-w.
|
Mrna decoding in human is kinetically and structurally
distinct from bacteria (ga state 2) . SNAP output
|
|
8g6r
|
replication |
cryo-EM (3.3 Å) |
Anderson TK, Hoferle PJ, Lee KW, Coon JJ,
Kirchdoerfer RN |
(2023) "An
alphacoronavirus polymerase structure reveals conserved
co-factor functions." Biorxiv. doi:
10.1101/2023.03.15.532841.
|
Porcine epidemic diarrhea virus core polymerase complex
. SNAP output
|
|
8g6w
|
ribosome |
cryo-EM (2.02 Å) |
Majumdar C, Walker JA, Francis MB, Schepartz A, Cate
JHD |
(2023) "Aminobenzoic
Acid Derivatives Obstruct Induced Fit in the Catalytic
Center of the Ribosome." Acs Cent.Sci.,
9, 1160-1169. doi: 10.1021/acscentsci.3c00153.
|
Structure of wt e.coli 70s ribosome complexed with
mrna, p-site fmet-nh-trnafmet and a-site
ortho-aminobenzoic acid charged nh-trnaphe . SNAP output
|
|
8g6x
|
ribosome |
cryo-EM (2.31 Å) |
Majumdar C, Walker JA, Francis MB, Schepartz A, Cate
JHD |
(2023) "Aminobenzoic
Acid Derivatives Obstruct Induced Fit in the Catalytic
Center of the Ribosome." Acs Cent.Sci.,
9, 1160-1169. doi: 10.1021/acscentsci.3c00153.
|
Structure of wt e.coli ribosome 50s subunit with
complexed with mrna, p-site fmet-nh-trnafmet and a-site
meta-aminobenzoic acid charged nh-trnaphe . SNAP output
|
|
8g6y
|
ribosome |
cryo-EM (2.09 Å) |
Majumdar C, Walker JA, Francis MB, Schepartz A, Cate
JHD |
(2023) "Aminobenzoic
Acid Derivatives Obstruct Induced Fit in the Catalytic
Center of the Ribosome." Acs Cent.Sci.,
9, 1160-1169. doi: 10.1021/acscentsci.3c00153.
|
Structure of wt e.coli ribosome 50s subunit with
complexed with mrna, p-site fmet-nh-trnafmet and a-site
3-aminopyridine-4-carboxylic acid charged nh-trnaphe .
SNAP output
|
|
8g7p
|
ribosome |
cryo-EM (2.9 Å) |
Rybak MY, Gagnon MG |
(2024) "Structures
of the ribosome bound to EF-Tu-isoleucine tRNA
elucidate the mechanism of AUG avoidance."
Nat.Struct.Mol.Biol., 31,
810-816. doi: 10.1038/s41594-024-01236-3.
|
Structure of the escherichia coli 70s ribosome in
complex with ef-tu and ile-trnaile(lau) bound to the
cognate aua codon (structure i) . SNAP output
|
|
8g7q
|
ribosome |
cryo-EM (3.1 Å) |
Rybak MY, Gagnon MG |
(2024) "Structures
of the ribosome bound to EF-Tu-isoleucine tRNA
elucidate the mechanism of AUG avoidance."
Nat.Struct.Mol.Biol., 31,
810-816. doi: 10.1038/s41594-024-01236-3.
|
Structure of the escherichia coli 70s ribosome in
complex with ef-tu and ile-trnaile(lau) bound to the
near-cognate aug codon (structure ii) . SNAP output
|
|
8g7r
|
ribosome |
cryo-EM (2.8 Å) |
Rybak MY, Gagnon MG |
(2024) "Structures
of the ribosome bound to EF-Tu-isoleucine tRNA
elucidate the mechanism of AUG avoidance."
Nat.Struct.Mol.Biol., 31,
810-816. doi: 10.1038/s41594-024-01236-3.
|
Structure of the escherichia coli 70s ribosome in
complex with a-site trnaile(lau) bound to the cognate
aua codon (structure iii) . SNAP output
|
|
8g7s
|
ribosome |
cryo-EM (3.1 Å) |
Rybak MY, Gagnon MG |
(2024) "Structures
of the ribosome bound to EF-Tu-isoleucine tRNA
elucidate the mechanism of AUG avoidance."
Nat.Struct.Mol.Biol., 31,
810-816. doi: 10.1038/s41594-024-01236-3.
|
Structure of the escherichia coli 70s ribosome in
complex with p-site trnaile(lau) bound to the cognate
aua codon (structure iv) . SNAP output
|
|
8g7t
|
transferase-hydrolase-RNA |
cryo-EM (3.2 Å) |
Wang W, Gotte B, Guo R, Pyle AM |
(2023) "The E3
ligase Riplet promotes RIG-I signaling independent of
RIG-I oligomerization." Nat Commun,
14, 7308. doi: 10.1038/s41467-023-42982-0.
|
cryo-EM structure of riplet:rig-i:dsrna complex
(end-end) . SNAP
output
|
|
8g7u
|
transferase-hydrolase-RNA |
cryo-EM (4.0 Å) |
Wang W, Gotte B, Guo R, Pyle AM |
(2023) "The E3
ligase Riplet promotes RIG-I signaling independent of
RIG-I oligomerization." Nat Commun,
14, 7308. doi: 10.1038/s41467-023-42982-0.
|
cryo-EM structure of riplet:rig-i:dsrna complex
(end-semi-closed end) . SNAP output
|
|
8g7v
|
transferase-hydrolase-RNA |
cryo-EM (3.9 Å) |
Wang W, Gotte B, Guo R, Pyle AM |
(2023) "The E3
ligase Riplet promotes RIG-I signaling independent of
RIG-I oligomerization." Nat Commun,
14, 7308. doi: 10.1038/s41467-023-42982-0.
|
cryo-EM structure of riplet:rig-i:dsrna complex
(end-inter) . SNAP
output
|
|
8g90
|
RNA binding protein-RNA |
X-ray (1.2 Å) |
Kozlov G, Jiang J, Rutherford T, Noronha AM, Wilds
CJ, Gehring K |
(2024) "Enhanced
binding of guanylated poly(A) RNA by the LaM domain of
LARP1." Rna Biol., 21,
7-16. doi: 10.1080/15476286.2024.2379121.
|
Lam domain of human larp1 in complex with sp
phosphorothioate isomer of aaaaa(sra) RNA . SNAP output
|
|
8g91
|
RNA binding protein-RNA |
X-ray (1.2 Å) |
Kozlov G, Jiang J, Rutherford T, Noronha AM, Wilds
CJ, Gehring K |
(2024) "Enhanced
binding of guanylated poly(A) RNA by the LaM domain of
LARP1." Rna Biol., 21,
7-16. doi: 10.1080/15476286.2024.2379121.
|
Lam domain of human larp1 in complex with rp
phosphorothioate isomer of aaaaa(sra) RNA . SNAP output
|
|
8g9s
|
hydrolase-RNA |
cryo-EM (3.4 Å) |
Hu C, Myers MT, Zhou X, Hou Z, Lozen ML, Nam KH,
Zhang Y, Ke A |
(2024) "Exploiting
activation and inactivation mechanisms in type I-C
CRISPR-Cas3 for genome-editing applications."
Mol.Cell, 84, 463-475.e5.
doi: 10.1016/j.molcel.2023.12.034.
|
Exploiting activation and inactivation mechanisms in
type i-c crispr-cas3 for genome editing applications .
SNAP output
|
|
8g9t
|
hydrolase-RNA |
cryo-EM (3.6 Å) |
Hu C, Myers MT, Zhou X, Hou Z, Lozen ML, Nam KH,
Zhang Y, Ke A |
(2024) "Exploiting
activation and inactivation mechanisms in type I-C
CRISPR-Cas3 for genome-editing applications."
Mol.Cell, 84, 463-475.e5.
doi: 10.1016/j.molcel.2023.12.034.
|
Exploiting activation and inactivation mechanisms in
type i-c crispr-cas3 for genome editing applications .
SNAP output
|
|
8gaf
|
hydrolase-RNA |
cryo-EM (3.64 Å) |
Hu C, Myers MT, Zhou X, Hou Z, Lozen ML, Nam KH,
Zhang Y, Ke A |
(2024) "Exploiting
activation and inactivation mechanisms in type I-C
CRISPR-Cas3 for genome-editing applications."
Mol.Cell, 84, 463-475.e5.
doi: 10.1016/j.molcel.2023.12.034.
|
Exploiting activation and inactivation mechanisms in
type i-c crispr-cas3 for genome editing applications .
SNAP output
|
|
8ghu
|
ribosome |
cryo-EM (3.0 Å) |
Srinivas P, Nosrati M, Zelinskaya N, Dey D, Comstock
LR, Dunham CM, Conn GL |
(2023) "30S
subunit recognition and G1405 modification by the
aminoglycoside-resistance 16S ribosomal RNA
methyltransferase RmtC." Biorxiv. doi:
10.1101/2023.03.13.532395.
|
Methyltransferase rmtc bound to the 30s ribosomal
subunit . SNAP
output
|
|
8glp
|
ribosome |
cryo-EM (1.67 Å) |
Holm M, Natchiar SK, Rundlet EJ, Myasnikov AG, Watson
ZL, Altman RB, Wang HY, Taunton J, Blanchard SC |
(2023) "mRNA
decoding in human is kinetically and structurally
distinct from bacteria." Nature,
617, 200-207. doi: 10.1038/s41586-023-05908-w.
|
Mrna decoding in human is kinetically and structurally
distinct from bacteria (consensus lsu focused refined
structure) . SNAP
output
|
|
8gna
|
RNA binding protein |
cryo-EM (2.8 Å) |
Wang X, Yu G, Wen Y, An Q, Li X, Liao F, Lian C,
Zhang K, Yin H, Wei Y, Deng Z, Zhang H |
(2022) "Target
RNA-guided protease activity in type III-E CRISPR-Cas
system." Nucleic Acids Res.,
50, 12913-12923. doi: 10.1093/nar/gkac1151.
|
Structure of the sbcas7-11-crrna-ntr complex . SNAP output
|
|
8gs2
|
RNA binding protein-RNA |
cryo-EM (2.84 Å) |
Kato K, Okazaki S, Schmitt-Ulms C, Jiang K, Zhou W,
Ishikawa J, Isayama Y, Adachi S, Nishizawa T, Makarova
KS, Koonin EV, Abudayyeh OO, Gootenberg JS, Nishimasu
H |
(2022) "RNA-triggered
protein cleavage and cell growth arrest by the type
III-E CRISPR nuclease-protease." Science,
378, 882-889. doi: 10.1126/science.add7347.
|
Structure of the cas7-11-csx29-guide RNA-target RNA
(non-matching pfs) complex . SNAP output
|
|
8gu6
|
RNA binding protein |
cryo-EM (3.1 Å) |
Wang X, Yu G, Wen Y, An Q, Li X, Liao F, Lian C,
Zhang K, Yin H, Wei Y, Deng Z, Zhang H |
(2022) "Target
RNA-guided protease activity in type III-E CRISPR-Cas
system." Nucleic Acids Res.,
50, 12913-12923. doi: 10.1093/nar/gkac1151.
|
Structure of the sbcas7-11-crrna-ntr-csx29 complex .
SNAP output
|
|
8gw1
|
viral protein |
cryo-EM (3.31 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
A mechanism for sars-cov-2 RNA capping and its
inhibition by nucleotide analogue inhibitors . SNAP output
|
|
8gwb
|
viral protein |
cryo-EM (2.75 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
Sars-cov-2 e-rtc complex with RNA-nsp9 . SNAP output
|
|
8gwe
|
viral protein |
cryo-EM (2.66 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
Sars-cov-2 e-rtc complex with RNA-nsp9 and gmppnp .
SNAP output
|
|
8gwf
|
viral protein |
cryo-EM (3.39 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
A mechanism for sars-cov-2 RNA capping and its
inhibition by nucleotide analogue inhibitors . SNAP output
|
|
8gwg
|
viral protein |
cryo-EM (3.37 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
A mechanism for sars-cov-2 RNA capping and its
inhibition by nucleotide analogue inhibitors . SNAP output
|
|
8gwi
|
viral protein |
cryo-EM (3.18 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
A mechanism for sars-cov-2 RNA capping and its
inhibition by nucleotide analogue inhibitors . SNAP output
|
|
8gwk
|
viral protein-inhibitor |
cryo-EM (2.72 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
Sars-cov-2 RNA e-rtc complex with rmp-nsp9 and gmppnp .
SNAP output
|
|
8gwm
|
viral protein-inhibitor |
cryo-EM (2.64 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
Sars-cov-2 e-rtc bound with mmp-nsp9 and gmppnp .
SNAP output
|
|
8gwn
|
viral protein |
cryo-EM (3.38 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
A mechanism for sars-cov-2 RNA capping and its
inhibitor of at-527 . SNAP output
|
|
8gwo
|
viral protein |
cryo-EM (3.8 Å) |
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S,
Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L,
Guddat LW, Gao Y, Rao Z, Lou Z |
(2022) "A
mechanism for SARS-CoV-2 RNA capping and its inhibition
by nucleotide analog inhibitors." Cell,
185, 4347-4360.e17. doi: 10.1016/j.cell.2022.09.037.
|
A mechanism for sars-cov-2 RNA capping and its
inhibition by nucleotide analogue inhibitors . SNAP output
|
|
8gxb
|
protein-RNA |
X-ray (2.15 Å) |
Xu X, Egger M, Li C, Chen H, Micura R, Ren A |
(2023) "Structure-based
investigations of the NAD+-II riboswitch."
Nucleic Acids Res., 51,
54-67. doi: 10.1093/nar/gkac1227.
|
Crystal structure of nad+ -ii riboswitch in complex
with nad+ . SNAP
output
|
|
8gxc
|
protein-RNA |
X-ray (2.5 Å) |
Xu X, Egger M, Li C, Chen H, Micura R, Ren A |
(2023) "Structure-based
investigations of the NAD+-II riboswitch."
Nucleic Acids Res., 51,
54-67. doi: 10.1093/nar/gkac1227.
|
Crystal structure of nad+ -ii riboswitch in complex
with nmn . SNAP
output
|
|
8gzp
|
viral protein |
cryo-EM (3.6 Å) |
Osawa T, Aoki M, Ehara H, Sekine SI |
(2023) "Structures
of dengue virus RNA replicase complexes."
Mol.Cell, 83, 2781. doi:
10.1016/j.molcel.2023.06.023.
|
cryo-EM structure of the ns5-sla complex . SNAP output
|
|
8gzq
|
viral protein |
cryo-EM (3.9 Å) |
Osawa T, Aoki M, Ehara H, Sekine SI |
(2023) "Structures
of dengue virus RNA replicase complexes."
Mol.Cell, 83, 2781. doi:
10.1016/j.molcel.2023.06.023.
|
cryo-EM structure of the ns5-ns3-sla complex . SNAP output
|
|
8gzr
|
viral protein |
cryo-EM (2.8 Å) |
Osawa T, Aoki M, Ehara H, Sekine SI |
(2023) "Structures
of dengue virus RNA replicase complexes."
Mol.Cell, 83, 2781. doi:
10.1016/j.molcel.2023.06.023.
|
cryo-EM structure of the the ns5-ns3 RNA-elongation
complex . SNAP
output
|
|
8h0i
|
antiviral protein |
cryo-EM (2.8 Å) |
Kouno T, Shibata S, Shigematsu M, Hyun J, Kim TG,
Matsuo H, Wolf M |
(2023) "Structural
insights into RNA bridging between HIV-1 Vif and
antiviral factor APOBEC3G." Nat Commun,
14, 4037. doi: 10.1038/s41467-023-39796-5.
|
cryo-EM structure of apobec3g-vif complex . SNAP output
|
|
8h0s
|
transferase-RNA |
X-ray (2.9 Å) |
Cho G, Lee J, Kim J |
(2023) "Identification
of a novel 5-aminomethyl-2-thiouridine
methyltransferase in tRNA modification."
Nucleic Acids Res., 51,
1971-1983. doi: 10.1093/nar/gkad048.
|
Crystal structure of mnmm from b. subtilis complexed
with gln-ttg anti-codon stem loop and sam (2.90 a) .
SNAP output
|
|
8h1b
|
transferase-RNA |
X-ray (1.55 Å) |
Cho G, Lee J, Kim J |
(2023) "Identification
of a novel 5-aminomethyl-2-thiouridine
methyltransferase in tRNA modification."
Nucleic Acids Res., 51,
1971-1983. doi: 10.1093/nar/gkad048.
|
Crystal structure of mnmm from s. aureus complexed with
sam and trna anti-codon stem loop (asl) (1.55 a) .
SNAP output
|
|
8h1c
|
ligase-RNA |
cryo-EM (4.5 Å) |
Yu Z, Wu Z, Li Y, Hao Q, Cao X, Blaha GM, Lin J, Lu
G |
(2023) "Structural
basis of a two-step tRNA recognition mechanism for
plastid glycyl-tRNA synthetase." Nucleic Acids
Res., 51, 4000-4011. doi:
10.1093/nar/gkad144.
|
cryo-EM structure of oryza sativa plastid glycyl-trna
synthetase in complex with two trnas (one in trna
binding state and the other in trna locked state) .
SNAP output
|
|
8h2h
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Lu Y, Liu N, Liu Y, Zheng L, Yang J, Wang J, Jia X,
Zi Q, Peng H, Rao Y, Wang HW |
(2022) "Functionalized
graphene grids with various charges for single-particle
cryo-EM." Nat Commun, 13,
6718. doi: 10.1038/s41467-022-34579-w.
|
cryo-EM structure of a group ii intron complexed with
its reverse transcriptase . SNAP output
|
|
8h69
|
viral protein |
cryo-EM (3.7 Å) |
Li H, Wu Y, Li M, Guo L, Gao Y, Wang Q, Zhang J, Lai
Z, Zhang X, Zhu L, Lan P, Rao Z, Liu Y, Liang H |
(2023) "An
intermediate state allows influenza polymerase to
switch smoothly between transcription and replication
cycles." Nat.Struct.Mol.Biol.,
30, 1183-1192. doi: 10.1038/s41594-023-01043-2.
|
cryo-EM structure of influenza RNA polymerase .
SNAP output
|
|
8h6e
|
splicing |
cryo-EM (3.2 Å) |
Zhang W, Zhang X, Zhan X, Bai R, Lei J, Yan C, Shi
Y |
(2024) "Structural
insights into human exon-defined spliceosome prior to
activation." Cell Res.,
34, 428-439. doi: 10.1038/s41422-024-00949-w.
|
cryo-EM structure of human exon-defined spliceosome in
the late pre-b state. . SNAP output
|
|
8h6j
|
splicing |
cryo-EM (3.25 Å) |
Zhang W, Zhang X, Zhan X, Bai R, Lei J, Yan C, Shi
Y |
(2024) "Structural
insights into human exon-defined spliceosome prior to
activation." Cell Res.,
34, 428-439. doi: 10.1038/s41422-024-00949-w.
|
cryo-EM structure of human exon-defined spliceosome in
the mature pre-b state. . SNAP output
|
|
8h6k
|
splicing |
cryo-EM (2.7 Å) |
Zhang W, Zhang X, Zhan X, Bai R, Lei J, Yan C, Shi
Y |
(2024) "Structural
insights into human exon-defined spliceosome prior to
activation." Cell Res.,
34, 428-439. doi: 10.1038/s41422-024-00949-w.
|
cryo-EM structure of human exon-defined spliceosome in
the mature b state. . SNAP output
|
|
8h6l
|
splicing |
cryo-EM (2.6 Å) |
Zhang W, Zhang X, Zhan X, Bai R, Lei J, Yan C, Shi
Y |
(2024) "Structural
insights into human exon-defined spliceosome prior to
activation." Cell Res.,
34, 428-439. doi: 10.1038/s41422-024-00949-w.
|
cryo-EM structure of human exon-defined spliceosome in
the early b state. . SNAP output
|
|
8h8e
|
membrane protein |
cryo-EM (3.81 Å) |
Chi P, Wang X, Li J, Yang H, Li K, Zhang Y, Lin S, Yu
L, Liu S, Chen L, Ren R, Wu J, Huang Z, Geng J, Deng
D |
(2024) "Molecular
insights into the inhibition of proton-activated
chloride channel by transfer RNA." Cell
Res., 34, 743-745. doi: 10.1038/s41422-024-00993-6.
|
Structure of the dimeric xenopus tropical
acid-sensitive outwardly rectifying channel asor trimer
bound with trna (closed state) . SNAP output
|
|
8h9d
|
DNA binding protein |
X-ray (3.1 Å) |
Jianwei L, Jobichen C, Machida S, Meng S, Read RJ,
Hongying C, Jian S, Yuan YA, Sivaraman J |
(2023) "Structures
of apo Cas12a and its complex with crRNA and DNA reveal
the dynamics of ternary complex formation and target
DNA cleavage." Plos Biol.,
21, e3002023. doi: 10.1371/journal.pbio.3002023.
|
Crystal structure of cas12a protein . SNAP output
|
|
8hf0
|
RNA binding protein-RNA |
cryo-EM (3.72 Å) |
Deng T, Su S, Yuan X, He J, Huang Y, Ma J, Wang
J |
(2023) "Structural
mechanism of R2D2 and Loqs-PD synergistic modulation on
DmDcr-2 oligomers." Nat Commun,
14, 5228. doi: 10.1038/s41467-023-40919-1.
|
Dmdcr-2-r2d2-loqspd with 50bp-dsrna in dimer state .
SNAP output
|
|
8hf1
|
RNA binding protein-RNA |
cryo-EM (3.7 Å) |
Deng T, Su S, Yuan X, He J, Huang Y, Ma J, Wang
J |
(2023) "Structural
mechanism of R2D2 and Loqs-PD synergistic modulation on
DmDcr-2 oligomers." Nat Commun,
14, 5228. doi: 10.1038/s41467-023-40919-1.
|
Dmdcr-2-r2d2-loqspd with 19bp-dsrna in trimer state .
SNAP output
|
|
8hfr
|
ribosome |
cryo-EM (2.64 Å) |
Li Z, Chen S, Zhao L, Huang G, Xu H, Yang X, Wang P,
Gao N, Sui SF |
(2023) "Nuclear
export of pre-60S particles through the nuclear pore
complex." Nature, 618,
411-418. doi: 10.1038/s41586-023-06128-y.
|
Npc-trapped pre-60s particle . SNAP output
|
|
8hio
|
RNA binding protein |
cryo-EM (3.73 Å) |
Omura SN, Nakagawa R, Sudfeld C, Villegas Warren R,
Wu WY, Hirano H, Laffeber C, Kusakizako T, Kise Y,
Lebbink JHG, Itoh Y, van der Oost J, Nureki O |
(2023) "Mechanistic
and evolutionary insights into a type V-M CRISPR-Cas
effector enzyme." Nat.Struct.Mol.Biol.,
30, 1172-1182. doi: 10.1038/s41594-023-01042-3.
|
cryo-EM structure of the cas12m2-crrna binary complex .
SNAP output
|
|
8hj4
|
hydrolase-RNA-antimicrobial protein |
cryo-EM (3.1 Å) |
Sun W, Zhao X, Wang J, Yang X, Cheng Z, Liu S, Wang
J, Sheng G, Wang Y |
(2023) "Anti-CRISPR
AcrIIC5 is a dsDNA mimic that inhibits type II-C Cas9
effectors by blocking PAM recognition." Nucleic
Acids Res., 51, 1984-1995. doi:
10.1093/nar/gkad052.
|
Cryoem structure of an anti-crispr protein acriic5
bound to nme1cas9-sgrna complex . SNAP output
|
|
8hk1
|
splicing |
cryo-EM (2.7 Å) |
Yang F, Bian T, Zhan X, Chen Z, Xing Z, Larsen NA,
Zhang X, Shi Y |
(2023) "Mechanisms
of the RNA helicases DDX42 and DDX46 in human U2 snRNP
assembly." Nat Commun,
14, 897. doi: 10.1038/s41467-023-36489-x.
|
The cryo-EM structure of human pre-17s u2 snrnp .
SNAP output
|
|
8hke
|
RNA binding protein |
cryo-EM (3.71 Å) |
Zhang J, Zhan C, Fan J, Wu D, Zhang R, Wu D, Chen X,
Lu Y, Li M, Lin M, Gong J, Jiang D |
(2024) "Structural
insights into double-stranded RNA recognition and
transport by SID-1." Nat.Struct.Mol.Biol.,
31, 1095-1104. doi: 10.1038/s41594-024-01276-9.
|
Dsrna transporter . SNAP
output
|
|
8hku
|
ribosome |
cryo-EM (2.72 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hkv
|
ribosome |
cryo-EM (4.94 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hkx
|
ribosome |
cryo-EM (3.14 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hky
|
ribosome |
cryo-EM (4.45 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hkz
|
ribosome |
cryo-EM (4.78 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hl1
|
ribosome |
cryo-EM (3.93 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hl2
|
ribosome |
cryo-EM (4.1 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hl3
|
ribosome |
cryo-EM (4.8 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hl4
|
ribosome |
cryo-EM (4.62 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hl5
|
ribosome |
cryo-EM (5.72 Å) |
Wang YH, Dai H, Zhang L, Wu Y, Wang J, Wang C, Xu CH,
Hou H, Yang B, Zhu Y, Zhang X, Zhou J |
(2023) "Cryo-electron
microscopy structure and translocation mechanism of the
crenarchaeal ribosome." Nucleic Acids
Res., 51, 8909-8924. doi:
10.1093/nar/gkad661.
|
cryo-EM structures and translocation mechanism of
crenarchaeota ribosome . SNAP output
|
|
8hmy
|
RNA binding protein-RNA |
cryo-EM (2.94 Å) |
Zhang X, Yang F, Zhan X, Bian T, Xing Z, Lu Y, Shi
Y |
(2023) "Structural
basis of pre-tRNA intron removal by human tRNA splicing
endonuclease." Mol.Cell,
83, 1328-1339.e4. doi: 10.1016/j.molcel.2023.03.015.
|
cryo-EM structure of the human pre-catalytic
tsen-pre-trna complex . SNAP output
|
|
8hmz
|
RNA binding protein-RNA |
cryo-EM (2.9 Å) |
Zhang X, Yang F, Zhan X, Bian T, Xing Z, Lu Y, Shi
Y |
(2023) "Structural
basis of pre-tRNA intron removal by human tRNA splicing
endonuclease." Mol.Cell,
83, 1328-1339.e4. doi: 10.1016/j.molcel.2023.03.015.
|
cryo-EM structure of the human post-catalytic
tsen-pre-trna complex . SNAP output
|
|
8hnt
|
immune system |
X-ray (3.06 Å) |
Sun W, Cheng Z, Wang J, Yang J, Li X, Wang J, Chen M,
Yang X, Sheng G, Lou J, Wang Y |
(2023) "AcrIIC4
inhibits type II-C Cas9 by preventing R-loop
formation." Proc.Natl.Acad.Sci.USA,
120, e2303675120. doi: 10.1073/pnas.2303675120.
|
Crystal structure of anti-crispr protein acriic4 bound
to hpacas9-sgrna surveillance complex . SNAP output
|
|
8hra
|
immune system |
cryo-EM (3.76 Å) |
Gao Y, Luo X, Li P, Li Z, Ye F, Liu S, Gao P |
(2023) "Molecular
basis of RADAR anti-phage supramolecular
assemblies." Cell, 186,
999-1012.e20. doi: 10.1016/j.cell.2023.01.026.
|
Structure of heptameric rdra ring in RNA-loading state
. SNAP output
|
|
8hrb
|
immune system |
cryo-EM (3.78 Å) |
Gao Y, Luo X, Li P, Li Z, Ye F, Liu S, Gao P |
(2023) "Molecular
basis of RADAR anti-phage supramolecular
assemblies." Cell, 186,
999-1012.e20. doi: 10.1016/j.cell.2023.01.026.
|
Structure of tetradecameric rdra ring in RNA-loading
state . SNAP output
|
|
8hsp
|
ribosome |
cryo-EM (2.32 Å) |
Akiyama N, Ishiguro K, Yokoyama T, Miyauchi K, Nagao
A, Shirouzu M, Suzuki T |
(2024) "Structural
insights into the decoding capability of isoleucine
tRNAs with lysidine and agmatidine."
Nat.Struct.Mol.Biol., 31,
817-825. doi: 10.1038/s41594-024-01238-1.
|
E. coli 70s ribosome complexed with trna_ile2 bearing
l34 and t6a37 in classical state . SNAP output
|
|
8htz
|
ribosome |
cryo-EM (2.4 Å) |
Akiyama N, Ishiguro K, Yokoyama T, Miyauchi K, Nagao
A, Shirouzu M, Suzuki T |
(2024) "Structural
insights into the decoding capability of isoleucine
tRNAs with lysidine and agmatidine."
Nat.Struct.Mol.Biol., 31,
817-825. doi: 10.1038/s41594-024-01238-1.
|
E. coli 70s ribosome complexed with h. marismortui
trna_ile2 bearing agm2c34 in classical state . SNAP output
|
|
8hu1
|
ribosome |
cryo-EM (2.69 Å) |
Akiyama N, Ishiguro K, Yokoyama T, Miyauchi K, Nagao
A, Shirouzu M, Suzuki T |
(2024) "Structural
insights into the decoding capability of isoleucine
tRNAs with lysidine and agmatidine."
Nat.Struct.Mol.Biol., 31,
817-825. doi: 10.1038/s41594-024-01238-1.
|
E. coli 70s ribosome complexed with trna_ile2 bearing
l34 and ct6a37 in classical state . SNAP output
|
|
8huj
|
translation |
cryo-EM (3.76 Å) |
Imai S, Suzuki H, Fujiyoshi Y, Shimada I |
(2023) "Dynamically
regulated two-site interaction of viral RNA to capture
host translation initiation factor." Nat
Commun, 14, 4977. doi: 10.1038/s41467-023-40582-6.
|
cryo-EM structure of the j-k-st region of emcv ires in
complex with eif4g-heat1 and eif4a . SNAP output
|
|
8i0p
|
splicing |
cryo-EM (3.4 Å) |
Zhan X, Lu Y, Shi Y |
(2024) "Molecular
basis for the activation of human spliceosome."
Nat Commun, 15, 6348. doi:
10.1038/s41467-024-50785-0.
|
The cryo-EM structure of human pre-bact complex .
SNAP output
|
|
8i0r
|
splicing |
cryo-EM (3.0 Å) |
Zhan X, Lu Y, Shi Y |
(2024) "Molecular
basis for the activation of human spliceosome."
Nat Commun, 15, 6348. doi:
10.1038/s41467-024-50785-0.
|
The cryo-EM structure of human bact-i complex .
SNAP output
|
|
8i0s
|
splicing |
cryo-EM (4.2 Å) |
Zhan X, Lu Y, Shi Y |
(2024) "Molecular
basis for the activation of human spliceosome."
Nat Commun, 15, 6348. doi:
10.1038/s41467-024-50785-0.
|
The cryo-EM structure of human bact-ii complex .
SNAP output
|
|
8i0t
|
splicing |
cryo-EM (3.0 Å) |
Zhan X, Lu Y, Shi Y |
(2024) "Molecular
basis for the activation of human spliceosome."
Nat Commun, 15, 6348. doi:
10.1038/s41467-024-50785-0.
|
The cryo-EM structure of human bact-iii complex .
SNAP output
|
|
8i0u
|
splicing |
cryo-EM (3.3 Å) |
Zhan X, Lu Y, Shi Y |
(2024) "Molecular
basis for the activation of human spliceosome."
Nat Commun, 15, 6348. doi:
10.1038/s41467-024-50785-0.
|
The cryo-EM structure of human bact-iv complex .
SNAP output
|
|
8i0v
|
splicing |
cryo-EM (3.0 Å) |
Zhan X, Lu Y, Shi Y |
(2024) "Molecular
basis for the activation of human spliceosome."
Nat Commun, 15, 6348. doi:
10.1038/s41467-024-50785-0.
|
The cryo-EM structure of human post-bact complex .
SNAP output
|
|
8i0w
|
splicing |
cryo-EM (3.4 Å) |
Zhan X, Lu Y, Shi Y |
(2024) "Molecular
basis for the activation of human spliceosome."
Nat Commun, 15, 6348. doi:
10.1038/s41467-024-50785-0.
|
The cryo-EM structure of human c complex . SNAP output
|
|
8i3q
|
RNA binding protein |
cryo-EM (3.1 Å) |
Liu M, Li Z, Chen J, Lin J, Lu Q, Ye Y, Zhang H,
Zhang B, Ouyang S |
(2023) "Structural
transitions upon guide RNA binding and their importance
in Cas12g-mediated RNA cleavage." Plos
Genet., 19, e1010930. doi:
10.1371/journal.pgen.1010930.
|
cryo-EM structure of cas12g-sgrna binary complex .
SNAP output
|
|
8i7j
|
ribosome |
cryo-EM (4.6 Å) |
Datey A, Sharma P, Khaja FT, Rahil H, Hussain T |
(2025) "Yeast
Eukaryotic Initiation Factor 4B Remodels the MRNA Entry
Site on the Small Ribosomal Subunit."
Biochemistry. doi: 10.1021/acs.biochem.4c00489.
|
Yeast 40s-eif4b - partially open conformation of the
40s head . SNAP
output
|
|
8i88
|
viral protein-antiviral protein |
cryo-EM (3.7 Å) |
Wang X, Li X, Yu G, Zhang L, Zhang C, Wang Y, Liao F,
Wen Y, Yin H, Liu X, Wei Y, Li Z, Deng Z, Zhang H |
(2023) "Structural
insights into mechanisms of Argonaute
protein-associated NADase activation in bacterial
immunity." Cell Res., 33,
699-711. doi: 10.1038/s41422-023-00839-7.
|
cryo-EM structure of tir-apaz-ago-grna complex .
SNAP output
|
|
8i9p
|
ribosome |
cryo-EM (3.0 Å) |
Lau B, Huang Z, Kellner N, Niu S, Berninghausen O,
Beckmann R, Hurt E, Cheng J |
(2023) "Mechanism
of 5S RNP recruitment and helicase-surveilled rRNA
maturation during pre-60S biogenesis." Embo
Rep., 24, e56910. doi: 10.15252/embr.202356910.
|
cryo-EM structure of a chaetomium thermophilum pre-60s
ribosomal subunit - state mak16 . SNAP output
|
|
8i9r
|
ribosome |
cryo-EM (3.1 Å) |
Lau B, Huang Z, Kellner N, Niu S, Berninghausen O,
Beckmann R, Hurt E, Cheng J |
(2023) "Mechanism
of 5S RNP recruitment and helicase-surveilled rRNA
maturation during pre-60S biogenesis." Embo
Rep., 24, e56910. doi: 10.15252/embr.202356910.
|
cryo-EM structure of a chaetomium thermophilum pre-60s
ribosomal subunit - state 5s rnp . SNAP output
|
|
8i9t
|
ribosome |
cryo-EM (3.6 Å) |
Lau B, Huang Z, Kellner N, Niu S, Berninghausen O,
Beckmann R, Hurt E, Cheng J |
(2023) "Mechanism
of 5S RNP recruitment and helicase-surveilled rRNA
maturation during pre-60S biogenesis." Embo
Rep., 24, e56910. doi: 10.15252/embr.202356910.
|
cryo-EM structure of a chaetomium thermophilum pre-60s
ribosomal subunit - state dbp10-1 . SNAP output
|
|
8i9v
|
ribosome |
cryo-EM (3.1 Å) |
Lau B, Huang Z, Kellner N, Niu S, Berninghausen O,
Beckmann R, Hurt E, Cheng J |
(2023) "Mechanism
of 5S RNP recruitment and helicase-surveilled rRNA
maturation during pre-60S biogenesis." Embo
Rep., 24, e56910. doi: 10.15252/embr.202356910.
|
cryo-EM structure of a chaetomium thermophilum pre-60s
ribosomal subunit - state dbp10-2 . SNAP output
|
|
8i9w
|
ribosome |
cryo-EM (3.1 Å) |
Lau B, Huang Z, Kellner N, Niu S, Berninghausen O,
Beckmann R, Hurt E, Cheng J |
(2023) "Mechanism
of 5S RNP recruitment and helicase-surveilled rRNA
maturation during pre-60S biogenesis." Embo
Rep., 24, e56910. doi: 10.15252/embr.202356910.
|
cryo-EM structure of a chaetomium thermophilum pre-60s
ribosomal subunit - dbp10-3 . SNAP output
|
|
8i9x
|
ribosome |
cryo-EM (2.8 Å) |
Lau B, Huang Z, Kellner N, Niu S, Berninghausen O,
Beckmann R, Hurt E, Cheng J |
(2023) "Mechanism
of 5S RNP recruitment and helicase-surveilled rRNA
maturation during pre-60S biogenesis." Embo
Rep., 24, e56910. doi: 10.15252/embr.202356910.
|
cryo-EM structure of a chaetomium thermophilum pre-60s
ribosomal subunit - ytm1-1 . SNAP output
|
|
8i9y
|
ribosome |
cryo-EM (3.1 Å) |
Lau B, Huang Z, Kellner N, Niu S, Berninghausen O,
Beckmann R, Hurt E, Cheng J |
(2023) "Mechanism
of 5S RNP recruitment and helicase-surveilled rRNA
maturation during pre-60S biogenesis." Embo
Rep., 24, e56910. doi: 10.15252/embr.202356910.
|
cryo-EM structure of a chaetomium thermophilum pre-60s
ribosomal subunit - ytm1-2 . SNAP output
|
|
8i9z
|
ribosome |
cryo-EM (2.7 Å) |
Lau B, Huang Z, Kellner N, Niu S, Berninghausen O,
Beckmann R, Hurt E, Cheng J |
(2023) "Mechanism
of 5S RNP recruitment and helicase-surveilled rRNA
maturation during pre-60S biogenesis." Embo
Rep., 24, e56910. doi: 10.15252/embr.202356910.
|
cryo-EM structure of a chaetomium thermophilum pre-60s
ribosomal subunit - state spb4 . SNAP output
|
|
8ia0
|
ribosome |
cryo-EM (2.7 Å) |
Lau B, Huang Z, Kellner N, Niu S, Berninghausen O,
Beckmann R, Hurt E, Cheng J |
(2023) "Mechanism
of 5S RNP recruitment and helicase-surveilled rRNA
maturation during pre-60S biogenesis." Embo
Rep., 24, e56910. doi: 10.15252/embr.202356910.
|
cryo-EM structure of a chaetomium thermophilum pre-60s
ribosomal subunit - state puf6 . SNAP output
|
|
8iby
|
RNA binding protein-RNA |
cryo-EM (3.47 Å) |
Deng P, Tan SQ, Yang QY, Fu L, Wu Y, Zhu HZ, Sun L,
Bao Z, Lin Y, Zhang QC, Wang H, Wang J, Liu JG |
(2023) "Structural
RNA components supervise the sequential DNA cleavage in
R2 retrotransposon." Cell,
186, 2865-2879.e20. doi: 10.1016/j.cell.2023.05.032.
|
Structure of r2 with 5'orf . SNAP output
|
|
8ibz
|
RNA binding protein-RNA |
cryo-EM (3.04 Å) |
Deng P, Tan SQ, Yang QY, Fu L, Wu Y, Zhu HZ, Sun L,
Bao Z, Lin Y, Zhang QC, Wang H, Wang J, Liu JG |
(2023) "Structural
RNA components supervise the sequential DNA cleavage in
R2 retrotransposon." Cell,
186, 2865-2879.e20. doi: 10.1016/j.cell.2023.05.032.
|
Structure of r2 with 5'orf and 3'utr . SNAP output
|
|
8id2
|
RNA binding protein-RNA |
X-ray (1.8 Å) |
Nameki N, Terawaki SI, Takizawa M, Kitamura M, Muto
Y, Kuwasako K |
(2023) "Structural
insights into recognition of SL4, the UUCG stem-loop,
of human U1 snRNA by the ubiquitin-like domain,
including the C-terminal tail in the SF3A1 subunit of
U2 snRNP." J.Biochem.,
174, 203-216. doi: 10.1093/jb/mvad033.
|
Crystal structure of the ubiquitin-like domain in the
sf3a1 subunit of human u2 snrnp complexed with the
stem-loop 4 of u1 snrna . SNAP output
|
|
8idf
|
transferase-RNA |
X-ray (3.7 Å) |
Yamashita S, Tomita K |
(2023) "Mechanism
of U6 snRNA oligouridylation by human TUT1."
Nat Commun, 14, 4686. doi:
10.1038/s41467-023-40420-9.
|
Crystal structure of human tut1 complexed with u6 snrna
. SNAP output
|
|
8idt
|
ribosome |
cryo-EM (2.8 Å) |
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N,
Gao N |
(2023) "Visualizing
the nucleoplasmic maturation of human pre-60S ribosomal
particles." Cell Res.,
33, 867-878. doi: 10.1038/s41422-023-00853-9.
|
Human nuclear pre-60s ribosomal particle - state g .
SNAP output
|
|
8ie3
|
ribosome |
cryo-EM (3.3 Å) |
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N,
Gao N |
(2023) "Visualizing
the nucleoplasmic maturation of human pre-60S ribosomal
particles." Cell Res.,
33, 867-878. doi: 10.1038/s41422-023-00853-9.
|
Human nuclear pre-60s ribosomal particle - state e .
SNAP output
|
|
8ifb
|
ribosome |
cryo-EM (2.43 Å) |
Tomono J, Asano K, Chiashi T, Suzuki M, Igarashi M,
Takahashi Y, Tanaka Y, Yokoyama T |
(2024) "Direct
visualization of ribosomes in the cell-free system
revealed the functional evolution of
aminoglycoside." J.Biochem.,
175, 587-598. doi: 10.1093/jb/mvae002.
|
Dibekacin-bound e.coli 70s ribosome in the pure system
. SNAP output
|
|
8ifc
|
ribosome |
cryo-EM (2.9 Å) |
Tomono J, Asano K, Chiashi T, Suzuki M, Igarashi M,
Takahashi Y, Tanaka Y, Yokoyama T |
(2024) "Direct
visualization of ribosomes in the cell-free system
revealed the functional evolution of
aminoglycoside." J.Biochem.,
175, 587-598. doi: 10.1093/jb/mvae002.
|
Arbekacin-bound e.coli 70s ribosome in the pure system
. SNAP output
|
|
8ine
|
ribosome |
cryo-EM (3.2 Å) |
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N,
Gao N |
(2023) "Visualizing
the nucleoplasmic maturation of human pre-60S ribosomal
particles." Cell Res.,
33, 867-878. doi: 10.1038/s41422-023-00853-9.
|
Human nuclear pre-60s ribosomal particle - state g' .
SNAP output
|
|
8ink
|
ribosome |
cryo-EM (3.2 Å) |
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N,
Gao N |
(2023) "Visualizing
the nucleoplasmic maturation of human pre-60S ribosomal
particles." Cell Res.,
33, 867-878. doi: 10.1038/s41422-023-00853-9.
|
Human nuclear pre-60s ribosomal particle - state d .
SNAP output
|
|
8ip8
|
translation |
cryo-EM (2.9 Å) |
Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K,
Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T,
Fujiwara T |
(2024) "Boric
acid intercepts 80S ribosome migration from AUG-stop by
stabilizing eRF1." Nat.Chem.Biol.,
20, 605-614. doi: 10.1038/s41589-023-01513-0.
|
Wheat 80s ribosome stalled on aug-stop boron
dependently . SNAP
output
|
|
8ip9
|
translation |
cryo-EM (3.0 Å) |
Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K,
Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T,
Fujiwara T |
(2024) "Boric
acid intercepts 80S ribosome migration from AUG-stop by
stabilizing eRF1." Nat.Chem.Biol.,
20, 605-614. doi: 10.1038/s41589-023-01513-0.
|
Wheat 40s ribosome in complex with a trnai . SNAP output
|
|
8ipa
|
translation |
cryo-EM (3.4 Å) |
Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K,
Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T,
Fujiwara T |
(2024) "Boric
acid intercepts 80S ribosome migration from AUG-stop by
stabilizing eRF1." Nat.Chem.Biol.,
20, 605-614. doi: 10.1038/s41589-023-01513-0.
|
Wheat 80s ribosome stalled on aug-stop boron
dependently with cycloheximide . SNAP output
|
|
8ipb
|
translation |
cryo-EM (3.4 Å) |
Tanaka M, Yokoyama T, Saito H, Nishimoto M, Tsuda K,
Sotta N, Shigematsu H, Shirouzu M, Iwasaki S, Ito T,
Fujiwara T |
(2024) "Boric
acid intercepts 80S ribosome migration from AUG-stop by
stabilizing eRF1." Nat.Chem.Biol.,
20, 605-614. doi: 10.1038/s41589-023-01513-0.
|
Wheat 80s ribosome pausing on aug-stop with
cycloheximide . SNAP
output
|
|
8ipd
|
ribosome |
cryo-EM (3.2 Å) |
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N,
Gao N |
(2023) "Visualizing
the nucleoplasmic maturation of human pre-60S ribosomal
particles." Cell Res.,
33, 867-878. doi: 10.1038/s41422-023-00853-9.
|
Human nuclear pre-60s ribosomal particle - state c .
SNAP output
|
|
8ipm
|
ribosomal protein |
X-ray (3.1 Å) |
Lv M, Zhou W, Hao Y, Li F, Zhang H, Yao X, Shi Y,
Zhang L |
(2024) "Structural
insights into the specific recognition of mitochondrial
ribosome-binding factor hsRBFA and 12 S rRNA by
methyltransferase METTL15." Cell Discov,
10, 11. doi: 10.1038/s41421-023-00634-z.
|
The structure of human mitochondrial methyltransferase
mettl15 with h44_rna, rbfa and sam . SNAP output
|
|
8ipx
|
ribosome |
cryo-EM (4.3 Å) |
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N,
Gao N |
(2023) "Visualizing
the nucleoplasmic maturation of human pre-60S ribosomal
particles." Cell Res.,
33, 867-878. doi: 10.1038/s41422-023-00853-9.
|
Human nuclear pre-60s ribosomal particle - state c' .
SNAP output
|
|
8ipy
|
ribosome |
cryo-EM (3.2 Å) |
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N,
Gao N |
(2023) "Visualizing
the nucleoplasmic maturation of human pre-60S ribosomal
particles." Cell Res.,
33, 867-878. doi: 10.1038/s41422-023-00853-9.
|
Human nuclear pre-60s ribosomal particle - state d' .
SNAP output
|
|
8ir1
|
ribosome |
cryo-EM (3.3 Å) |
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N,
Gao N |
(2023) "Visualizing
the nucleoplasmic maturation of human pre-60S ribosomal
particles." Cell Res.,
33, 867-878. doi: 10.1038/s41422-023-00853-9.
|
Human nuclear pre-60s ribosomal particle - state a .
SNAP output
|
|
8ir3
|
ribosome |
cryo-EM (3.5 Å) |
Zhang Y, Liang X, Luo S, Chen Y, Li Y, Ma C, Li N,
Gao N |
(2023) "Visualizing
the nucleoplasmic maturation of human pre-60S ribosomal
particles." Cell Res.,
33, 867-878. doi: 10.1038/s41422-023-00853-9.
|
Human nuclear pre-60s ribosomal particle - state b' .
SNAP output
|
|
8iss
|
structural protein |
cryo-EM (3.19 Å) |
Yuan L, Han Y, Zhao J, Zhang Y, Sun Y |
(2023) "Recognition
and cleavage mechanism of intron-containing pre-tRNA by
human TSEN endonuclease complex." Nat
Commun, 14, 6071. doi: 10.1038/s41467-023-41845-y.
|
cryo-EM structure of wild-type human trna splicing
endonuclease complex bound to pre-trna-arg at 3.19 Å
resolution . SNAP
output
|
|
8iuo
|
viral protein |
cryo-EM (3.96 Å) |
Wang Y, Zhang C, Luo Y, Ling X, Luo B, Jia G, Su D,
Dong H, Su Z |
(2023) "Cryo-EM
structure of the nucleocapsid-like assembly of
respiratory syncytial virus." Signal Transduct
Target Ther, 8, 323. doi:
10.1038/s41392-023-01602-5.
|
Respiratory syncytial virus nucleocapsid-like assembly
. SNAP output
|
|
8j1z
|
ribosome |
cryo-EM (2.6 Å) |
Yu T, Jiang J, Yu Q, Li X, Dong W, Zeng F |
"PTC Remodeling in Pre50S Intermediates: Insights
into the Role of DEAD-box RNA Helicase DbpA." |
The global structure of pre50s related to dbpa in
state3 . SNAP output
|
|
8j62
|
antiviral protein |
cryo-EM (2.5 Å) |
Kouno T, Shibata S, Shigematsu M, Hyun J, Kim TG,
Matsuo H, Wolf M |
(2023) "Structural
insights into RNA bridging between HIV-1 Vif and
antiviral factor APOBEC3G." Nat Commun,
14, 4037. doi: 10.1038/s41467-023-39796-5.
|
cryo-EM structure of apobec3g-vif complex . SNAP output
|
|
8j72
|
RNA binding protein |
X-ray (3.16 Å) |
Shi F, Zhang K, Cheng Q, Che S, Zhi S, Yu Z, Liu F,
Duan F, Wang Y, Yang N |
(2024) "Molecular
mechanism governing RNA-binding property of mammalian
TRIM71 protein." Sci Bull (Beijing),
69, 72-81. doi: 10.1016/j.scib.2023.11.041.
|
Crystal structure of mammalian trim71 in complex with
lncrna trincr1 . SNAP
output
|
|
8j7r
|
translation |
cryo-EM (3.7 Å) |
Imai S, Suzuki H, Fujiyoshi Y, Shimada I |
(2023) "Dynamically
regulated two-site interaction of viral RNA to capture
host translation initiation factor." Nat
Commun, 14, 4977. doi: 10.1038/s41467-023-40582-6.
|
cryo-EM structure of the j-k-st region of emcv ires in
complex with eif4g-heat1 and eif4a (j-k-st-eif4g
focused) . SNAP
output
|
|
8ja0
|
RNA binding protein-RNA |
cryo-EM (3.52 Å) |
Li X, Liao F, Gao J, Song G, Zhang C, Ji N, Wang X,
Wen J, He J, Wei Y, Zhang H, Li Z, Yu G, Yin H |
(2023) "Inhibitory
mechanism of CRISPR-Cas9 by AcrIIC4." Nucleic
Acids Res., 51, 9442-9451. doi:
10.1093/nar/gkad669.
|
cryo-EM structure of the nmecas9-sgrna-acriic4 ternary
complex . SNAP
output
|
|
8jbb
|
hydrolase |
X-ray (1.81 Å) |
Du L, Zhu Q, Lin Z |
(2024) "Molecular
mechanism of allosteric activation of the CRISPR
ribonuclease Csm6 by cyclic tetra-adenylate."
Embo J., 43, 304-315. doi:
10.1038/s44318-023-00017-w.
|
Crystal structure of the csm6 from thermus thermophilus
hb8 in complex with a2>p . SNAP output
|
|
8jdj
|
ribosome |
cryo-EM (2.5 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the human cytoplasmic ribosome with human
trna asp(q34) and mrna(gau) . SNAP output
|
|
8jdk
|
ribosome |
cryo-EM (2.26 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the human cytoplasmic ribosome with human
trna asp(manq34) and mrna(gau) . SNAP output
|
|
8jdl
|
ribosome |
cryo-EM (2.42 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the human cytoplasmic ribosome with human
trna tyr(galq34) and mrna(uau) (non-rotated state) .
SNAP output
|
|
8jdm
|
ribosome |
cryo-EM (2.67 Å) |
Zhao X, Ma D, Ishiguro K, Saito H, Akichika S,
Matsuzawa I, Mito M, Irie T, Ishibashi K, Wakabayashi K,
Sakaguchi Y, Yokoyama T, Mishima Y, Shirouzu M, Iwasaki
S, Suzuki T, Suzuki T |
(2023) "Glycosylated
queuosines in tRNAs optimize translational rate and
post-embryonic growth." Cell,
186, 5517. doi: 10.1016/j.cell.2023.10.026.
|
Structure of the human cytoplasmic ribosome with human
trna tyr(galq34) and mrna(uau) (rotated state) .
SNAP output
|
|
8jft
|
viral protein |
cryo-EM (3.31 Å) |
Deng X, Sun W, Li X, Wang J, Cheng Z, Sheng G, Wang
Y |
(2024) "An
anti-CRISPR that represses its own transcription while
blocking Cas9-target DNA binding." Nat
Commun, 15, 1806. doi: 10.1038/s41467-024-45987-5.
|
cryo-EM structure of sacas9-acriia15 ctd-sgrna complex
. SNAP output
|
|
8jh1
|
hydrolase |
X-ray (2.89 Å) |
Du L, Zhu Q, Lin Z |
(2024) "Molecular
mechanism of allosteric activation of the CRISPR
ribonuclease Csm6 by cyclic tetra-adenylate."
Embo J., 43, 304-315. doi:
10.1038/s44318-023-00017-w.
|
Crystal structure of the csm6 y161a mutant from thermus
thermophilus hb8 in complex with cyclic-tetraadenylate
(ca4) . SNAP output
|
|
8jiv
|
ribosome |
cryo-EM (2.84 Å) |
Mishra RK, Sharma P, Khaja FT, Uday AB, Hussain
T |
(2024) "Cryo-EM
structure of wheat ribosome reveals unique features of
the plant ribosomes." Structure,
32, 562. doi: 10.1016/j.str.2024.02.006.
|
Atomic structure of wheat ribosome reveals unique
features of the plant ribosomes . SNAP output
|
|
8jiw
|
translation |
cryo-EM (2.88 Å) |
Mishra RK, Sharma P, Khaja FT, Uday AB, Hussain
T |
(2024) "Cryo-EM
structure of wheat ribosome reveals unique features of
the plant ribosomes." Structure,
32, 562. doi: 10.1016/j.str.2024.02.006.
|
Atomic structure of wheat ribosome reveals unique
features of the plant ribosomes . SNAP output
|
|
8joz
|
transferase-RNA |
X-ray (2.22 Å) |
Yoo J, Lee J, Kim J |
(2023) "Structural
basis for the selective methylation of
5-carboxymethoxyuridine in tRNA modification."
Nucleic Acids Res., 51,
9432-9441. doi: 10.1093/nar/gkad668.
|
Crystal structure of cmom from e. coli complexed with
sinefungin and cellularly expressed trna ser . SNAP output
|
|
8jsg
|
translation |
cryo-EM (4.6 Å) |
Uday AB, Mishra RK, Hussain T |
(2025) "Initiation
factor 3 bound to the 30S ribosomal subunit in an
initial step of translation." Proteins,
93, 279-286. doi: 10.1002/prot.26655.
|
Structure of the 30s-if3 complex from escherichia coli
. SNAP output
|
|
8jsh
|
translation |
cryo-EM (4.4 Å) |
Uday AB, Mishra RK, Hussain T |
(2025) "Initiation
factor 3 bound to the 30S ribosomal subunit in an
initial step of translation." Proteins,
93, 279-286. doi: 10.1002/prot.26655.
|
Structure of the 30s-body-if3 complex from escherichia
coli . SNAP output
|
|
8jsl
|
viral protein-RNA |
cryo-EM (2.95 Å) |
Peng Q, Yuan B, Cheng J, Wang M, Gao S, Bai S, Zhao
X, Qi J, Gao GF, Shi Y |
(2023) "Molecular
mechanism of de novo replication by the Ebola virus
polymerase." Nature, 622,
603-610. doi: 10.1038/s41586-023-06608-1.
|
The structure of ebov l-vp35-RNA complex . SNAP output
|
|
8jsm
|
viral protein-RNA |
cryo-EM (3.3 Å) |
Peng Q, Yuan B, Cheng J, Wang M, Gao S, Bai S, Zhao
X, Qi J, Gao GF, Shi Y |
(2023) "Molecular
mechanism of de novo replication by the Ebola virus
polymerase." Nature, 622,
603-610. doi: 10.1038/s41586-023-06608-1.
|
The structure of ebov l-vp35-RNA complex (conformation
1) . SNAP output
|
|
8jsn
|
viral protein-RNA |
cryo-EM (3.4 Å) |
Peng Q, Yuan B, Cheng J, Wang M, Gao S, Bai S, Zhao
X, Qi J, Gao GF, Shi Y |
(2023) "Molecular
mechanism of de novo replication by the Ebola virus
polymerase." Nature, 622,
603-610. doi: 10.1038/s41586-023-06608-1.
|
The structure of ebov l-vp35-RNA complex (conformation
2) . SNAP output
|
|
8jtr
|
RNA binding protein-RNA |
cryo-EM (3.21 Å) |
Shen P, Zhang L, Liu B, Li X, Wang C, Min J, Huang
JW, Chen CC, Guo RT |
(2024) "Structure of Geobacillus stearothermophilus
Cas9: Insights into the Catalytic Process and
Thermostability of CRISPR-Cas9." Acs
Catalysis, 14, 13227-13235. doi:
10.1021/acscatal.4c03278.
|
cryo-EM structure of geocas9-sgrna binary complex .
SNAP output
|
|
8jy0
|
RNA |
X-ray (2.75 Å) |
Zhang Y, Xu Z, Xiao Y, Jiang H, Zuo X, Li X, Fang
X |
(2024) "Structural
mechanisms for binding and activation of a
contact-quenched fluorophore by RhoBAST." Nat
Commun, 15, 4206. doi: 10.1038/s41467-024-48478-9.
|
Crystal structure of rhobast complexed with tmr-dn .
SNAP output
|
|
8k0k
|
RNA binding protein-RNA |
X-ray (2.995 Å) |
Zhang L, Wang H, Zeng J, Cao X, Gao Z, Liu Z, Li F,
Wang J, Zhang Y, Yang M, Feng Y |
(2024) "Cas1
mediates the interference stage in a phage-encoded
CRISPR-Cas system." Nat.Chem.Biol.,
20, 1471-1481. doi: 10.1038/s41589-024-01659-5.
|
Crystal structure of csy complex . SNAP output
|
|
8k2a
|
ribosome |
cryo-EM (2.9 Å) |
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R,
Cheng J |
(2024) "Structural
basis for differential inhibition of eukaryotic
ribosomes by tigecycline." Nat Commun,
15, 5481. doi: 10.1038/s41467-024-49797-7.
|
cryo-EM structure of the human 55s mitoribosome with
tigecycline . SNAP
output
|
|
8k2b
|
ribosome |
cryo-EM (3.4 Å) |
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R,
Cheng J |
(2024) "Structural
basis for differential inhibition of eukaryotic
ribosomes by tigecycline." Nat Commun,
15, 5481. doi: 10.1038/s41467-024-49797-7.
|
cryo-EM structure of the human 39s mitoribosome with
tigecycline . SNAP
output
|
|
8k2d
|
ribosome |
cryo-EM (3.2 Å) |
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R,
Cheng J |
(2024) "Structural
basis for differential inhibition of eukaryotic
ribosomes by tigecycline." Nat Commun,
15, 5481. doi: 10.1038/s41467-024-49797-7.
|
cryo-EM structure of the yeast 80s ribosome with
tigecycline, eef2, stm1 and eif5a . SNAP output
|
|
8k34
|
structural protein-RNA |
cryo-EM (2.81 Å) |
Zhang JT, Wei XY, Cui N, Tian R, Jia N |
(2024) "Target
ssDNA activates the NADase activity of prokaryotic
SPARTA immune system." Nat.Chem.Biol.,
20, 503-511. doi: 10.1038/s41589-023-01479-z.
|
cryo-EM structure of sparta grna binary complex .
SNAP output
|
|
8k3o
|
ribosome |
cryo-EM (3.88 Å) |
Afsar M, Shukla A, Ali F, Maurya RK, Bharti S, Kumar
N, Sadik M, Chandra S, Rahil H, Kumar S, Ansari I, Jahan
F, Habib S, Hussain T, Krishnan MY, Ramachandran R |
(2024) "Bacterial
Rps3 counters oxidative and UV stress by recognizing
and processing AP-sites on mRNA via a novel
mechanism." Nucleic Acids Res.,
52, 13996-14012. doi: 10.1093/nar/gkae1130.
|
cryo-EM structure of 30s ribosome with cleaved ap-mrna
bound complex i . SNAP
output
|
|
8k4e
|
ribosome |
cryo-EM (3.4 Å) |
Afsar M, Shukla A, Ali F, Maurya RK, Bharti S, Kumar
N, Sadik M, Chandra S, Rahil H, Kumar S, Ansari I, Jahan
F, Habib S, Hussain T, Krishnan MY, Ramachandran R |
(2024) "Bacterial
Rps3 counters oxidative and UV stress by recognizing
and processing AP-sites on mRNA via a novel
mechanism." Nucleic Acids Res.,
52, 13996-14012. doi: 10.1093/nar/gkae1130.
|
cryo-EM structure of 30s ribosome with cleaved ap-mrna
bound complex-ii . SNAP
output
|
|
8k82
|
ribosome |
cryo-EM (3.0 Å) |
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R,
Cheng J |
(2024) "Structural
basis for differential inhibition of eukaryotic
ribosomes by tigecycline." Nat Commun,
15, 5481. doi: 10.1038/s41467-024-49797-7.
|
cryo-EM structure of the yeast 80s ribosome with
tigecycline, not5 and p-site trna . SNAP output
|
|
8kab
|
ribosome |
cryo-EM (3.3 Å) |
Srinivasan K, Banerjee A, Sengupta J |
(2024) "Cryo-EM
structures reveal the molecular mechanism of
HflX-mediated erythromycin resistance in
mycobacteria." Structure,
32, 1443. doi: 10.1016/j.str.2024.06.016.
|
Mycobacterium smegmatis 50s ribosomal subunit-hflx
complex . SNAP
output
|
|
8kag
|
RNA binding protein-RNA |
X-ray (3.88 Å) |
Chen J, Chen Y, Huang L, Lin X, Chen H, Xiang W, Liu
L |
(2025) "Trans-nuclease
activity of Cas9 activated by DNA or RNA target
binding." Nat.Biotechnol.,
43, 558-568. doi: 10.1038/s41587-024-02255-7.
|
Crystal structure of spycas9 in complex with sgrna and
target RNA . SNAP
output
|
|
8kbc
|
viral protein |
X-ray (2.8 Å) |
Li D, Xiao Y, Fedorova I, Xiong W, Wang Y, Liu X,
Huiting E, Ren J, Gao Z, Zhao X, Cao X, Zhang Y,
Bondy-Denomy J, Feng Y |
(2024) "Single
phage proteins sequester signals from TIR and cGAS-like
enzymes." Nature, 635,
719-727. doi: 10.1038/s41586-024-08122-4.
|
Structure of cmtad1 complexed with caaa . SNAP output
|
|
8kbd
|
viral protein-RNA |
X-ray (3.15 Å) |
Li D, Xiao Y, Fedorova I, Xiong W, Wang Y, Liu X,
Huiting E, Ren J, Gao Z, Zhao X, Cao X, Zhang Y,
Bondy-Denomy J, Feng Y |
(2024) "Single
phage proteins sequester signals from TIR and cGAS-like
enzymes." Nature, 635,
719-727. doi: 10.1038/s41586-024-08122-4.
|
Structure of cmtad1 complexed with caag . SNAP output
|
|
8kbf
|
viral protein |
X-ray (2.31 Å) |
Li D, Xiao Y, Fedorova I, Xiong W, Wang Y, Liu X,
Huiting E, Ren J, Gao Z, Zhao X, Cao X, Zhang Y,
Bondy-Denomy J, Feng Y |
(2024) "Single
phage proteins sequester signals from TIR and cGAS-like
enzymes." Nature, 635,
719-727. doi: 10.1038/s41586-024-08122-4.
|
Structure of cbtad1 complexed with 1',3'-cadpr and ca3
. SNAP output
|
|
8kbh
|
viral protein |
X-ray (1.54 Å) |
Li D, Xiao Y, Fedorova I, Xiong W, Wang Y, Liu X,
Huiting E, Ren J, Gao Z, Zhao X, Cao X, Zhang Y,
Bondy-Denomy J, Feng Y |
(2024) "Single
phage proteins sequester signals from TIR and cGAS-like
enzymes." Nature, 635,
719-727. doi: 10.1038/s41586-024-08122-4.
|
Structure of cbtad1 complexed with 2',3'-cgamp and ca3
. SNAP output
|
|
8kd9
|
hydrolase-RNA complex |
cryo-EM (2.87 Å) |
Teramoto T, Koyasu T, Yokogawa T, Adachi N, Mayanagi
K, Nakamura T, Senda T, Kakuta Y |
(2025) "Structural basis of transfer RNA processing by
bacterial minimal RNase P." Nat Commun,
16, 5456. doi: 10.1038/s41467-025-60002-1.
|
cryo-EM structure of aquifex aeolicus minimal
protein-only rnase p (harp) in complex with pre-trnas .
SNAP output
|
|
8kda
|
hydrolase-RNA |
cryo-EM (3.19 Å) |
Teramoto T, Koyasu T, Yokogawa T, Adachi N, Mayanagi
K, Nakamura T, Senda T, Kakuta Y |
(2025) "Structural basis of transfer RNA processing by
bacterial minimal RNase P." Nat Commun,
16, 5456. doi: 10.1038/s41467-025-60002-1.
|
cryo-EM structure of hydrogenobacter thermophilus
minimal protein-only rnase p (harp) in complex with
pre-trnas . SNAP
output
|
|
8kgf
|
DNA binding protein-RNA |
cryo-EM (2.9 Å) |
Feng Y, Zhang X, Shi J, Ma P, Tang J, Huang X |
"A novel CRISPR/Cas12a in complex with a crRNA." |
Structure of amcas12a with crrna . SNAP output
|
|
8ki7
|
viral protein-RNA |
cryo-EM (3.7 Å) |
Li J, Cao L, Zhao Y, Shen J, Wang L, Feng M, Zhu M,
Ye Y, Kormelink R, Tao X, Wang X |
(2025) "Structural
basis for the activation of plant bunyavirus
replication machinery and its dual-targeted inhibition
by ribavirin." Nat.Plants,
11, 518-530. doi: 10.1038/s41477-025-01940-y.
|
Structure of tomato spotted wilt virus l protein
contained endoh domain binding to 3'5'vrna . SNAP output
|
|
8ki8
|
viral protein-RNA |
cryo-EM (3.2 Å) |
Li J, Cao L, Zhao Y, Shen J, Wang L, Feng M, Zhu M,
Ye Y, Kormelink R, Tao X, Wang X |
(2025) "Structural
basis for the activation of plant bunyavirus
replication machinery and its dual-targeted inhibition
by ribavirin." Nat.Plants,
11, 518-530. doi: 10.1038/s41477-025-01940-y.
|
Structure of tomato spotted wilt virus l protein
binding to 5'vrna . SNAP
output
|
|
8kie
|
ribosome |
cryo-EM (2.5 Å) |
Li X, Yu T, Li Q, Zeng F |
"Structure basis of translation regulation by YchF
bound to ribosome." |
Structure of ychf with 50s ribosomal subunit (local
map) . SNAP output
|
|
8oeq
|
ribosome |
X-ray (3.3 Å) |
Kolosova O, Zgadzay Y, Yusupov M |
(2025) "Mechanism of read-through enhancement by
aminoglycosides and mefloquine."
Proc.Natl.Acad.Sci.USA. doi: 10.1073/pnas.2420261122.
|
Crystal structure of the candida albicans 80s ribosome
in complex with paromomycin (250um) . SNAP output
|
|
8ogj
|
ribosome |
cryo-EM (3.1 Å) |
Kolosova O, Zgadzay Y, Yusupov M |
(2025) "Mechanism of read-through enhancement by
aminoglycosides and mefloquine."
Proc.Natl.Acad.Sci.USA. doi: 10.1073/pnas.2420261122.
|
Structure of candida albicans 80s ribosome in complex
with mefloquine . SNAP
output
|
|
8oh6
|
ribosome |
X-ray (3.35 Å) |
Kolosova O, Zgadzay Y, Yusupov M |
(2025) "Mechanism of read-through enhancement by
aminoglycosides and mefloquine."
Proc.Natl.Acad.Sci.USA. doi: 10.1073/pnas.2420261122.
|
Crystal structure of the candida albicans 80s ribosome
in complex with paromomycin (500umol) . SNAP output
|
|
8ohd
|
ribosome |
cryo-EM (3.1 Å) |
DaRosa PA, Penchev I, Gumbin SC, Scavone F, Wachalska
M, Paulo JA, Ordureau A, Peter JJ, Kulathu Y, Harper JW,
Becker T, Beckmann R, Kopito RR |
(2024) "UFM1 E3
ligase promotes recycling of 60S ribosomal subunits
from the ER." Nature,
627, 445-452. doi: 10.1038/s41586-024-07073-0.
|
60s ribosomal subunit bound to the e3-ufm1 complex -
state 3 (native) . SNAP
output
|
|
8oi5
|
ribosome |
X-ray (2.9 Å) |
Kolosova O, Zgadzay Y, Yusupov M |
(2025) "Mechanism of read-through enhancement by
aminoglycosides and mefloquine."
Proc.Natl.Acad.Sci.USA. doi: 10.1073/pnas.2420261122.
|
Crystal structure of the candida albicans 80s ribosome
in complex with paromomycin (2mm) . SNAP output
|
|
8oin
|
ribosome |
cryo-EM (3.6 Å) |
Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A,
Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R,
Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban
N |
(2023) "Molecular
basis of translation termination at noncanonical stop
codons in human mitochondria." Science,
380, 531-536. doi: 10.1126/science.adf9890.
|
55s mammalian mitochondrial ribosome with mtrf1 and
p-site trna . SNAP
output
|
|
8oip
|
ribosome |
cryo-EM (3.6 Å) |
Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A,
Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R,
Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban
N |
(2023) "Molecular
basis of translation termination at noncanonical stop
codons in human mitochondria." Science,
380, 531-536. doi: 10.1126/science.adf9890.
|
28s mammalian mitochondrial small ribosomal subunit
with mtrf1 and p-site trna . SNAP output
|
|
8oiq
|
ribosome |
cryo-EM (3.5 Å) |
Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A,
Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R,
Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban
N |
(2023) "Molecular
basis of translation termination at noncanonical stop
codons in human mitochondria." Science,
380, 531-536. doi: 10.1126/science.adf9890.
|
39s mammalian mitochondrial large ribosomal subunit
with mtrf1 and p-site trna . SNAP output
|
|
8oir
|
ribosome |
cryo-EM (3.1 Å) |
Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A,
Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R,
Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban
N |
(2023) "Molecular
basis of translation termination at noncanonical stop
codons in human mitochondria." Science,
380, 531-536. doi: 10.1126/science.adf9890.
|
55s human mitochondrial ribosome with mtrf1 and p-site
trna . SNAP output
|
|
8ois
|
ribosome |
cryo-EM (3.0 Å) |
Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A,
Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R,
Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban
N |
(2023) "Molecular
basis of translation termination at noncanonical stop
codons in human mitochondria." Science,
380, 531-536. doi: 10.1126/science.adf9890.
|
28s human mitochondrial small ribosomal subunit with
mtrf1 and p-site trna . SNAP output
|
|
8oit
|
ribosome |
cryo-EM (2.9 Å) |
Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A,
Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R,
Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban
N |
(2023) "Molecular
basis of translation termination at noncanonical stop
codons in human mitochondria." Science,
380, 531-536. doi: 10.1126/science.adf9890.
|
39s human mitochondrial large ribosomal subunit with
mtrf1 and p-site trna . SNAP output
|
|
8oiv
|
transferase |
X-ray (2.12 Å) |
Skvara P, Chalupska D, Klima M, Kozic J, Silhan J,
Boura E |
(2023) "Structural
basis for RNA-cap recognition and methylation by the
mpox methyltransferase VP39." Antiviral
Res., 216, 105663. doi: 10.1016/j.antiviral.2023.105663.
|
Monkeypox virus vp39 in complex with sah and cap0 .
SNAP output
|
|
8oj0
|
ribosome |
cryo-EM (3.3 Å) |
DaRosa PA, Penchev I, Gumbin SC, Scavone F, Wachalska
M, Paulo JA, Ordureau A, Peter JJ, Kulathu Y, Harper JW,
Becker T, Beckmann R, Kopito RR |
(2024) "UFM1 E3
ligase promotes recycling of 60S ribosomal subunits
from the ER." Nature,
627, 445-452. doi: 10.1038/s41586-024-07073-0.
|
60s ribosomal subunit bound to the e3-ufm1 complex -
state 2 (native) . SNAP
output
|
|
8oj3
|
ribosome |
X-ray (3.5 Å) |
Kolosova O, Zgadzay Y, Yusupov M |
(2025) "Mechanism of read-through enhancement by
aminoglycosides and mefloquine."
Proc.Natl.Acad.Sci.USA. doi: 10.1073/pnas.2420261122.
|
Crystal structure of the candida albicans 80s ribosome
in complex with geneticin g418 (rotated state) .
SNAP output
|
|
8oj5
|
ribosome |
cryo-EM (2.9 Å) |
DaRosa PA, Penchev I, Gumbin SC, Scavone F, Wachalska
M, Paulo JA, Ordureau A, Peter JJ, Kulathu Y, Harper JW,
Becker T, Beckmann R, Kopito RR |
(2024) "UFM1 E3
ligase promotes recycling of 60S ribosomal subunits
from the ER." Nature,
627, 445-452. doi: 10.1038/s41586-024-07073-0.
|
60s ribosomal subunit bound to the e3-ufm1 complex -
state 3 (in-vitro reconstitution) . SNAP output
|
|
8oj8
|
ribosome |
cryo-EM (3.3 Å) |
DaRosa PA, Penchev I, Gumbin SC, Scavone F, Wachalska
M, Paulo JA, Ordureau A, Peter JJ, Kulathu Y, Harper JW,
Becker T, Beckmann R, Kopito RR |
(2024) "UFM1 E3
ligase promotes recycling of 60S ribosomal subunits
from the ER." Nature,
627, 445-452. doi: 10.1038/s41586-024-07073-0.
|
60s ribosomal subunit bound to the e3-ufm1 complex -
state 1 (native) . SNAP
output
|
|
8okd
|
RNA binding protein |
cryo-EM (3.1 Å) |
Lin TY, Kleemann L, Jezowski J, Dobosz D, Rawski M,
Indyka P, Wazny G, Mehta R, Chramiec-Glabik A, Koziej L,
Ranff T, Fufezan C, Wawro M, Kochan J, Bereta J, Leidel
SA, Glatt S |
(2024) "The
molecular basis of tRNA selectivity by human
pseudouridine synthase 3." Mol.Cell,
84, 2472-2489.e8. doi: 10.1016/j.molcel.2024.06.013.
|
Human pseudouridine synthase 3 and trna-gln . SNAP output
|
|
8om2
|
ribosome |
cryo-EM (2.57 Å) |
Ast T, Itoh Y, Sadre S, McCoy JG, Namkoong G, Wengrod
JC, Chicherin I, Joshi PR, Kamenski P, Suess DLM, Amunts
A, Mootha VK |
(2024) "METTL17
is an Fe-S cluster checkpoint for mitochondrial
translation." Mol.Cell,
84, 359. doi: 10.1016/j.molcel.2023.12.016.
|
Small subunit of yeast mitochondrial ribosome in
complex with mettl17-rsm22. . SNAP output
|
|
8om3
|
ribosome |
cryo-EM (2.87 Å) |
Ast T, Itoh Y, Sadre S, McCoy JG, Namkoong G, Wengrod
JC, Chicherin I, Joshi PR, Kamenski P, Suess DLM, Amunts
A, Mootha VK |
(2024) "METTL17
is an Fe-S cluster checkpoint for mitochondrial
translation." Mol.Cell,
84, 359. doi: 10.1016/j.molcel.2023.12.016.
|
Small subunit of yeast mitochondrial ribosome in
complex with if3-aim23. . SNAP output
|
|
8om4
|
ribosome |
cryo-EM (2.32 Å) |
Ast T, Itoh Y, Sadre S, McCoy JG, Namkoong G, Wengrod
JC, Chicherin I, Joshi PR, Kamenski P, Suess DLM, Amunts
A, Mootha VK |
(2024) "METTL17
is an Fe-S cluster checkpoint for mitochondrial
translation." Mol.Cell,
84, 359. doi: 10.1016/j.molcel.2023.12.016.
|
Small subunit of yeast mitochondrial ribosome. .
SNAP output
|
|
8omr
|
RNA binding protein |
cryo-EM (3.3 Å) |
Sievers K, Neumann P, Susac L, Da Vela S, Graewert M,
Trowitzsch S, Svergun D, Tampe R, Ficner R |
(2024) "Structural
and functional insights into tRNA recognition by human
tRNA guanine transglycosylase." Structure,
32, 316. doi: 10.1016/j.str.2023.12.006.
|
Human trna guanine transglycosylase (tgt) bound to
trnaasp . SNAP
output
|
|
8ony
|
metal binding protein |
cryo-EM (2.92 Å) |
Klein MA, Wild K, Kisonaite M, Sinning I |
(2024) "Methionine
aminopeptidase 2 and its autoproteolysis product have
different binding sites on the ribosome." Nat
Commun, 15, 716. doi: 10.1038/s41467-024-44862-7.
|
Human methionine aminopeptidase 2 at the 80s ribosome .
SNAP output
|
|
8onz
|
metal binding protein |
cryo-EM (2.94 Å) |
Klein MA, Wild K, Kisonaite M, Sinning I |
(2024) "Methionine
aminopeptidase 2 and its autoproteolysis product have
different binding sites on the ribosome." Nat
Commun, 15, 716. doi: 10.1038/s41467-024-44862-7.
|
Chaetomium thermophilum methionine aminopeptidase 2 at
the 80s ribosome . SNAP
output
|
|
8oo0
|
metal binding protein |
cryo-EM (3.1 Å) |
Klein MA, Wild K, Kisonaite M, Sinning I |
(2024) "Methionine
aminopeptidase 2 and its autoproteolysis product have
different binding sites on the ribosome." Nat
Commun, 15, 716. doi: 10.1038/s41467-024-44862-7.
|
Chaetomium thermophilum methionine aminopeptidase 2
autoproteolysis product at the 80s ribosome . SNAP output
|
|
8oou
|
viral protein |
cryo-EM (2.9 Å) |
Gonnin L, Desfosses A, Bacia-Verloop M, Chevret D,
Galloux M, Eleouet JF, Gutsche I |
(2023) "Structural
landscape of the respiratory syncytial virus
nucleocapsids." Nat Commun,
14, 5732. doi: 10.1038/s41467-023-41439-8.
|
Double-ring nucleocapsid of the respiratory syncytial
virus . SNAP output
|
|
8op1
|
viral protein |
cryo-EM (3.5 Å) |
Gonnin L, Desfosses A, Bacia-Verloop M, Chevret D,
Galloux M, Eleouet JF, Gutsche I |
(2023) "Structural
landscape of the respiratory syncytial virus
nucleocapsids." Nat Commun,
14, 5732. doi: 10.1038/s41467-023-41439-8.
|
Subsection of a helical nucleocapsid of the respiratory
syncytial virus . SNAP
output
|
|
8op2
|
viral protein |
cryo-EM (2.8 Å) |
Gonnin L, Desfosses A, Bacia-Verloop M, Chevret D,
Galloux M, Eleouet JF, Gutsche I |
(2023) "Structural
landscape of the respiratory syncytial virus
nucleocapsids." Nat Commun,
14, 5732. doi: 10.1038/s41467-023-41439-8.
|
Stacks of nucleocapsid rings of the n1-370 mutant of
the human respiratory syncytial virus . SNAP output
|
|
8opc
|
virus like particle |
cryo-EM (2.99 Å) |
Kavcic L, Kezar A, Koritnik N, Znidaric MT, Klobucar
T, Vicic Z, Merzel F, Holden E, Benesch JLP, Podobnik
M |
(2024) "From
structural polymorphism to structural metamorphosis of
the coat protein of flexuous filamentous potato virus
Y." Commun Chem, 7, 14.
doi: 10.1038/s42004-024-01100-x.
|
Virus-like particle based on pvy coat protein with
helical architecture encapsidating ssrna . SNAP output
|
|
8ope
|
virus like particle |
cryo-EM (3.09 Å) |
Kavcic L, Kezar A, Koritnik N, Znidaric MT, Klobucar
T, Vicic Z, Merzel F, Holden E, Benesch JLP, Podobnik
M |
(2024) "From
structural polymorphism to structural metamorphosis of
the coat protein of flexuous filamentous potato virus
Y." Commun Chem, 7, 14.
doi: 10.1038/s42004-024-01100-x.
|
Virus-like particle based on pvy coat protein with dc40
deletion with helical architecture encapsidating ssrna
. SNAP output
|
|
8opl
|
virus like particle |
cryo-EM (2.41 Å) |
Kavcic L, Kezar A, Koritnik N, Znidaric MT, Klobucar
T, Vicic Z, Merzel F, Holden E, Benesch JLP, Podobnik
M |
(2024) "From
structural polymorphism to structural metamorphosis of
the coat protein of flexuous filamentous potato virus
Y." Commun Chem, 7, 14.
doi: 10.1038/s42004-024-01100-x.
|
Virus-like particle based on pvy coat protein with t43c
and d136c mutation with helical architecture
encapsidating ssrna . SNAP output
|
|
8opp
|
RNA |
cryo-EM (3.76 Å) |
Yi G, Ye M, Carrique L, El-Sagheer A, Brown T,
Norbury CJ, Zhang P, Gilbert RJC |
(2024) "Structural
basis for activity switching in polymerases determining
the fate of let-7 pre-miRNAs."
Nat.Struct.Mol.Biol., 31,
1426-1438. doi: 10.1038/s41594-024-01357-9.
|
Structure of human terminal uridylyltransferase 7
(htut7-zcchc6) bound with pre-let7g mirna and utpalphas
. SNAP output
|
|
8ops
|
RNA |
cryo-EM (3.82 Å) |
Yi G, Ye M, Carrique L, El-Sagheer A, Brown T,
Norbury CJ, Zhang P, Gilbert RJC |
(2024) "Structural
basis for activity switching in polymerases determining
the fate of let-7 pre-miRNAs."
Nat.Struct.Mol.Biol., 31,
1426-1438. doi: 10.1038/s41594-024-01357-9.
|
Human terminal uridylyltransferase 7 (tut7-zcchc6)
bound with pre-let7g mirna and lin28a - complex 1 .
SNAP output
|
|
8opt
|
RNA binding protein |
cryo-EM (3.65 Å) |
Yi G, Ye M, Carrique L, El-Sagheer A, Brown T,
Norbury CJ, Zhang P, Gilbert RJC |
(2024) "Structural
basis for activity switching in polymerases determining
the fate of let-7 pre-miRNAs."
Nat.Struct.Mol.Biol., 31,
1426-1438. doi: 10.1038/s41594-024-01357-9.
|
Human terminal uridylyltransferase 7 (tut7-zcchc6)
bound with pre-let7g mirna and lin28a - complex 2 .
SNAP output
|
|
8ost
|
cell cycle |
cryo-EM (3.69 Å) |
Yi G, Ye M, Carrique L, El-Sagheer A, Brown T,
Norbury CJ, Zhang P, Gilbert RJC |
(2024) "Structural
basis for activity switching in polymerases determining
the fate of let-7 pre-miRNAs."
Nat.Struct.Mol.Biol., 31,
1426-1438. doi: 10.1038/s41594-024-01357-9.
|
Structure of human terminal uridylyltransferase 4
(tut4, zcchc11) in complex with pre-let7g mirna and
lin28a . SNAP output
|
|
8oue
|
RNA binding protein |
cryo-EM (2.7 Å) |
Ghanim GE, Sekne Z, Balch S, van Roon AM, Nguyen
THD |
(2024) "2.7
angstrom cryo-EM structure of human telomerase H/ACA
ribonucleoprotein." Nat Commun,
15, 746. doi: 10.1038/s41467-024-45002-x.
|
The h-aca rnp lobe of human telomerase with the
dyskerin thumb loop in a semi-closed conformation .
SNAP output
|
|
8ouf
|
RNA binding protein |
cryo-EM (3.1 Å) |
Ghanim GE, Sekne Z, Balch S, van Roon AM, Nguyen
THD |
(2024) "2.7
angstrom cryo-EM structure of human telomerase H/ACA
ribonucleoprotein." Nat Commun,
15, 746. doi: 10.1038/s41467-024-45002-x.
|
The h-aca rnp lobe of human telomerase with the
dyskerin thumb loop in an open conformation . SNAP output
|
|
8ova
|
ribosome |
cryo-EM (2.47 Å) |
Rajan KS, Madmoni H, Bashan A, Taoka M, Aryal S, Nobe
Y, Doniger T, Galili Kostin B, Blumberg A,
Cohen-Chalamish S, Schwartz S, Rivalta A, Zimmerman E,
Unger R, Isobe T, Yonath A, Michaeli S |
(2023) "A single
pseudouridine on rRNA regulates ribosome structure and
function in the mammalian parasite Trypanosoma
brucei." Nat Commun, 14,
7462. doi: 10.1038/s41467-023-43263-6.
|
cryo-EM structure of trypanosoma brucei procyclic form
80s ribosome : parental strain . SNAP output
|
|
8ove
|
ribosome |
cryo-EM (2.6 Å) |
Rajan KS, Madmoni H, Bashan A, Taoka M, Aryal S, Nobe
Y, Doniger T, Galili Kostin B, Blumberg A,
Cohen-Chalamish S, Schwartz S, Rivalta A, Zimmerman E,
Unger R, Isobe T, Yonath A, Michaeli S |
(2023) "A single
pseudouridine on rRNA regulates ribosome structure and
function in the mammalian parasite Trypanosoma
brucei." Nat Commun, 14,
7462. doi: 10.1038/s41467-023-43263-6.
|
cryo-EM structure of trypanosoma brucei procyclic form
80s ribosome : tb11cs6h1 snorna mutant . SNAP output
|
|
8ovj
|
ribosome |
cryo-EM (2.4 Å) |
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H,
Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka
M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E,
Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF,
Yonath A, Michaeli S |
(2024) "Structural
and mechanistic insights into the function of
Leishmania ribosome lacking a single pseudouridine
modification." Cell Rep,
43, 114203. doi: 10.1016/j.celrep.2024.114203.
|
cryo-EM structure of leishmania major 80s ribosome :
parental strain . SNAP
output
|
|
8oz0
|
translation |
cryo-EM (3.5 Å) |
Brito Querido J, Sokabe M, Diaz-Lopez I, Gordiyenko
Y, Fraser CS, Ramakrishnan V |
(2024) "The
structure of a human translation initiation complex
reveals two independent roles for the helicase
eIF4A." Nat.Struct.Mol.Biol.,
31, 455-464. doi: 10.1038/s41594-023-01196-0.
|
Structure of a human 48s translation initiation complex
with eif4f and eif4a . SNAP output
|
|
8p03
|
translation |
cryo-EM (3.04 Å) |
Guca E, Alarcon R, Palo MZ, Santos L, Alonso-Gil S,
Davyt M, de Lima LHF, Boissier F, Das S, Zagrovic B,
Puglisi JD, Hashem Y, Ignatova Z |
(2024) "N 6
-methyladenosine in 5' UTR does not promote translation
initiation." Mol.Cell,
84, 584-595.e6. doi: 10.1016/j.molcel.2023.12.028.
|
48s late-stage initiation complex with m6a mrna .
SNAP output
|
|
8p09
|
translation |
cryo-EM (3.3 Å) |
Guca E, Alarcon R, Palo MZ, Santos L, Alonso-Gil S,
Davyt M, de Lima LHF, Boissier F, Das S, Zagrovic B,
Puglisi JD, Hashem Y, Ignatova Z |
(2024) "N 6
-methyladenosine in 5' UTR does not promote translation
initiation." Mol.Cell,
84, 584-595.e6. doi: 10.1016/j.molcel.2023.12.028.
|
48s late-stage initiation complex with non methylated
mrna . SNAP output
|
|
8p0b
|
viral protein |
cryo-EM (2.87 Å) |
Kouba T, Cusack S |
"Thogoto virus polymerase." |
Thogoto virus polymerase in mode b conformation and
bound to 32-mer loop promoter RNA . SNAP output
|
|
8p0g
|
viral protein |
cryo-EM (3.17 Å) |
Kouba T, Cusack S |
"Thogoto virus polymerase." |
Thogoto virus polymerase in mode a conformation and
bound to 35-mer loop promoter RNA . SNAP output
|
|
8p0u
|
viral protein |
cryo-EM (2.92 Å) |
Kouba T, Cusack S |
"Thogoto virus polymerase." |
Thogoto virus polymerase in mode b conformation with
defined endonuclease domain and bound to 32-mer loop
promoter RNA . SNAP
output
|
|
8p16
|
ribosome |
cryo-EM (2.77 Å) |
Pundir S, Larsson DSD, Selmer M, Sanyal S |
"The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of RF1 in
bacteria." |
E167k rf2 on e. coli 70s release complex with ugg
(structure i) . SNAP
output
|
|
8p17
|
ribosome |
cryo-EM (2.78 Å) |
Pundir S, Larsson DSD, Selmer M, Sanyal S |
"The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of RF1 in
bacteria." |
E167k rf2 on e. coli 70s release complex with ugg
(structure ii) . SNAP
output
|
|
8p18
|
ribosome |
cryo-EM (2.77 Å) |
Pundir S, Larsson DSD, Selmer M, Sanyal S |
"The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of RF1 in
bacteria." |
E167k rf2 on e. coli 70s release complex with ugg
(structure iii) . SNAP
output
|
|
8p1m
|
viral protein |
cryo-EM (3.23 Å) |
Keown JR, Carrique L, Grimes JM |
"Structure of hantaan orthohantavirus (HTNV)
polymerase bound to 5'vRNA and NTP Mg." |
Structure of hantaan orthohantavirus (htnv) polymerase
bound to 5'vrna and ntp mg . SNAP output
|
|
8p1n
|
viral protein |
cryo-EM (2.79 Å) |
Keown JR, Carrique L, Nilsson-Payant BE, Fodor E,
Grimes JM |
(2024) "Structural
characterization of the full-length Hantaan virus
polymerase." Plos Pathog.,
20, e1012781. doi: 10.1371/journal.ppat.1012781.
|
Structure of hantaan orthohantavirus (htnv) polymerase
bound to 5'vrna . SNAP
output
|
|
8p2f
|
ribosome |
cryo-EM (2.44 Å) |
Gonzalez-Lopez A, Larsson DSD, Koripella RK, Cain BN,
Chavez MG, Hergenrother PJ, Sanyal S, Selmer M |
(2024) "Structures
of the Staphylococcus aureus ribosome inhibited by
fusidic acid and fusidic acid cyclopentane."
Sci Rep, 14, 14253. doi:
10.1038/s41598-024-64868-x.
|
Staphylococcus aureus 70s ribosome with elongation
factor g locked with fusidic acid cyclopentane in
post-translocational state . SNAP output
|
|
8p2g
|
ribosome |
cryo-EM (2.02 Å) |
Gonzalez-Lopez A, Larsson DSD, Koripella RK, Cain BN,
Chavez MG, Hergenrother PJ, Sanyal S, Selmer M |
(2024) "Structures
of the Staphylococcus aureus ribosome inhibited by
fusidic acid and fusidic acid cyclopentane."
Sci Rep, 14, 14253. doi:
10.1038/s41598-024-64868-x.
|
Staphylococcus aureus 70s ribosome with elongation
factor g locked with fusidic acid cyclopentane with a
trna in pe-e chimeric state . SNAP output
|
|
8p2h
|
ribosome |
cryo-EM (2.49 Å) |
Gonzalez-Lopez A, Larsson DSD, Koripella RK, Cain BN,
Chavez MG, Hergenrother PJ, Sanyal S, Selmer M |
(2024) "Structures
of the Staphylococcus aureus ribosome inhibited by
fusidic acid and fusidic acid cyclopentane."
Sci Rep, 14, 14253. doi:
10.1038/s41598-024-64868-x.
|
Staphylococcus aureus 70s ribosome with elongation
factor g locked with fusidic acid with a trna in pe-e
chimeric state . SNAP
output
|
|
8p2k
|
translation |
cryo-EM (2.9 Å) |
Gamerdinger M, Jia M, Schloemer R, Rabl L,
Jaskolowski M, Khakzar KM, Ulusoy Z, Wallisch A, Jomaa A,
Hunaeus G, Scaiola A, Diederichs K, Ban N, Deuerling
E |
(2023) "NAC
controls cotranslational N-terminal methionine excision
in eukaryotes." Science,
380, 1238-1243. doi: 10.1126/science.adg3297.
|
Ternary complex of translating ribosome, nac and metap1
. SNAP output
|
|
8p4v
|
ribosome |
X-ray (3.16 Å) |
Terrosu S, Nurullina L, Supantanapong N, Pak BS,
Nguyen S, Holm M, Wu C, Lin M, Horne D, Sachs MS,
Blanchard SC, Yusupov M, Vanderwal CD |
(2025) "Synthesis
of Differentially Halogenated Lissoclimide Analogues To
Probe Ribosome E-Site Binding." Acs
Chem.Biol., 20, 858-869. doi:
10.1021/acschembio.4c00825.
|
80s yeast ribosome in complex with haterumaimideq .
SNAP output
|
|
8p5d
|
ribosome |
cryo-EM (10.8 Å) |
McLaren M, Conners R, Isupov MN, Gil-Diez P, Gambelli
L, Gold VAM, Walter A, Connell SR, Williams B, Daum
B |
(2023) "CryoEM
reveals that ribosomes in microsporidian spores are
locked in a dimeric hibernating state." Nat
Microbiol, 8, 1834-1845. doi:
10.1038/s41564-023-01469-w.
|
Spraguea lophii ribosome in the closed conformation by
cryo sub tomogram averaging . SNAP output
|
|
8p60
|
ribosome |
cryo-EM (14.3 Å) |
McLaren M, Conners R, Isupov MN, Gil-Diez P, Gambelli
L, Gold VAM, Walter A, Connell SR, Williams B, Daum
B |
(2023) "CryoEM
reveals that ribosomes in microsporidian spores are
locked in a dimeric hibernating state." Nat
Microbiol, 8, 1834-1845. doi:
10.1038/s41564-023-01469-w.
|
Spraguea lophii ribosome dimer . SNAP output
|
|
8p6p
|
translation |
cryo-EM (3.2 Å) |
Xue L, Spahn CMT, Schacherl M, Mahamid J |
(2025) "Structural
insights into context-dependent inhibitory mechanisms
of chloramphenicol in cells."
Nat.Struct.Mol.Biol., 32,
257-267. doi: 10.1038/s41594-024-01441-0.
|
Mycoplasma pneumoniae small ribosomal subunit in
chloramphenicol-treated cells . SNAP output
|
|
8p7b
|
RNA binding protein |
cryo-EM (2.42 Å) |
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo
L, Basu S, Kaiser S, Schneider R, Kowalinski E |
(2024) "Structural
basis of tRNA recognition by the m 3 C RNA
methyltransferase METTL6 in complex with SerRS
seryl-tRNA synthetase."
Nat.Struct.Mol.Biol., 31,
1614-1624. doi: 10.1038/s41594-024-01341-3.
|
Cryoem structure of mettl6 trna serrs complex in a
1:2:2 stoichiometry . SNAP output
|
|
8p7c
|
RNA binding protein |
cryo-EM (3.7 Å) |
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo
L, Basu S, Kaiser S, Schneider R, Kowalinski E |
(2024) "Structural
basis of tRNA recognition by the m 3 C RNA
methyltransferase METTL6 in complex with SerRS
seryl-tRNA synthetase."
Nat.Struct.Mol.Biol., 31,
1614-1624. doi: 10.1038/s41594-024-01341-3.
|
Cryoem structure of mettl6 trna serrs complex in a
2:2:2 stoichiometry . SNAP output
|
|
8p7d
|
RNA binding protein |
cryo-EM (4.2 Å) |
Throll P, G Dolce L, Rico-Lastres P, Arnold K, Tengo
L, Basu S, Kaiser S, Schneider R, Kowalinski E |
(2024) "Structural
basis of tRNA recognition by the m 3 C RNA
methyltransferase METTL6 in complex with SerRS
seryl-tRNA synthetase."
Nat.Struct.Mol.Biol., 31,
1614-1624. doi: 10.1038/s41594-024-01341-3.
|
Cryoem structure of mettl6 trna serrs complex in a
1:1:2 stoichiometry . SNAP output
|
|
8p7x
|
translation |
cryo-EM (3.03 Å) |
Xue L, Spahn CMT, Schacherl M, Mahamid J |
(2025) "Structural
insights into context-dependent inhibitory mechanisms
of chloramphenicol in cells."
Nat.Struct.Mol.Biol., 32,
257-267. doi: 10.1038/s41594-024-01441-0.
|
Mycoplasma pneumoniae 70s ribosome in
chloramphenicol-treated cells . SNAP output
|
|
8p7y
|
translation |
cryo-EM (3.7 Å) |
Xue L, Spahn CMT, Schacherl M, Mahamid J |
(2025) "Structural
insights into context-dependent inhibitory mechanisms
of chloramphenicol in cells."
Nat.Struct.Mol.Biol., 32,
257-267. doi: 10.1038/s41594-024-01441-0.
|
Mycoplasma pneumoniae 70s ribosome with second s4
protein on large subunit . SNAP output
|
|
8p85
|
ribosome |
X-ray (2.9 Å) |
Terrosu S, Yusupov M |
"Role of Protein eL42 in the Ribosome Binding of
Synthetic Analogues of Natural Lissoclimides." |
80s yeast ribosome in complex with fluorolissoclimide .
SNAP output
|
|
8p8b
|
translation |
cryo-EM (2.9 Å) |
Xue L, Spahn CMT, Schacherl M, Mahamid J |
(2025) "Structural
insights into context-dependent inhibitory mechanisms
of chloramphenicol in cells."
Nat.Struct.Mol.Biol., 32,
257-267. doi: 10.1038/s41594-024-01441-0.
|
Mycoplasma pneumoniae large ribosomal subunit in
chloramphenicol-treated cells . SNAP output
|
|
8p8m
|
ribosome |
cryo-EM (2.66 Å) |
Banerjee A, Ataman M, Smialek MJ, Mookherjee D, Rabl
J, Mironov A, Mues L, Enkler L, Coto-Llerena M, Schmidt
A, Boehringer D, Piscuoglio S, Spang A, Mittal N, Zavolan
M |
(2024) "Ribosomal
protein RPL39L is an efficiency factor in the
cotranslational folding of a subset of proteins with
alpha helical domains." Nucleic Acids
Res., 52, 9028-9048. doi:
10.1093/nar/gkae630.
|
Yeast 60s ribosomal subunit, rpl39 deletion . SNAP output
|
|
8p8n
|
ribosome |
cryo-EM (2.15 Å) |
Banerjee A, Ataman M, Smialek MJ, Mookherjee D, Rabl
J, Mironov A, Mues L, Enkler L, Coto-Llerena M, Schmidt
A, Boehringer D, Piscuoglio S, Spang A, Mittal N, Zavolan
M |
(2024) "Ribosomal
protein RPL39L is an efficiency factor in the
cotranslational folding of a subset of proteins with
alpha helical domains." Nucleic Acids
Res., 52, 9028-9048. doi:
10.1093/nar/gkae630.
|
Mouse rpl39 integrated into the yeast 60s ribosomal
subunit . SNAP
output
|
|
8p8u
|
ribosome |
cryo-EM (2.23 Å) |
Banerjee A, Ataman M, Smialek MJ, Mookherjee D, Rabl
J, Mironov A, Mues L, Enkler L, Coto-Llerena M, Schmidt
A, Boehringer D, Piscuoglio S, Spang A, Mittal N, Zavolan
M |
(2024) "Ribosomal
protein RPL39L is an efficiency factor in the
cotranslational folding of a subset of proteins with
alpha helical domains." Nucleic Acids
Res., 52, 9028-9048. doi:
10.1093/nar/gkae630.
|
Yeast 60s ribosomal subunit . SNAP output
|
|
8p8v
|
translation |
cryo-EM (8.7 Å) |
Xue L, Spahn CMT, Schacherl M, Mahamid J |
(2025) "Structural
insights into context-dependent inhibitory mechanisms
of chloramphenicol in cells."
Nat.Struct.Mol.Biol., 32,
257-267. doi: 10.1038/s41594-024-01441-0.
|
Mycoplasma pneumoniae di-ribosome in
chloramphenicol-treated cells (leading 70s) . SNAP output
|
|
8p8w
|
translation |
cryo-EM (8.7 Å) |
Xue L, Spahn CMT, Schacherl M, Mahamid J |
(2025) "Structural
insights into context-dependent inhibitory mechanisms
of chloramphenicol in cells."
Nat.Struct.Mol.Biol., 32,
257-267. doi: 10.1038/s41594-024-01441-0.
|
Mycoplasma pneumoniae di-ribosome in
chloramphenicol-treated cells (following 70s) .
SNAP output
|
|
8p9a
|
ribosome |
X-ray (2.9 Å) |
Terrosu S, Nurullina L, Supantanapong N, Pak BS,
Nguyen S, Holm M, Wu C, Lin M, Horne D, Sachs MS,
Blanchard SC, Yusupov M, Vanderwal CD |
(2025) "Synthesis
of Differentially Halogenated Lissoclimide Analogues To
Probe Ribosome E-Site Binding." Acs
Chem.Biol., 20, 858-869. doi:
10.1021/acschembio.4c00825.
|
80s yeast ribosome in complex with methyllissoclimide .
SNAP output
|
|
8pdl
|
viral protein |
cryo-EM (3.1 Å) |
Whitehead JD, Decool H, Leyrat C, Carrique L, Fix J,
Eleouet JF, Galloux M, Renner M |
(2023) "Structure
of the N-RNA/P interface indicates mode of L/P
recruitment to the nucleocapsid of human
metapneumovirus." Nat Commun,
14, 7627. doi: 10.1038/s41467-023-43434-5.
|
10-mer ring of human metapneumovirus (hmpv) n-RNA .
SNAP output
|
|
8pdm
|
viral protein |
cryo-EM (3.3 Å) |
Whitehead JD, Decool H, Leyrat C, Carrique L, Fix J,
Eleouet JF, Galloux M, Renner M |
(2023) "Structure
of the N-RNA/P interface indicates mode of L/P
recruitment to the nucleocapsid of human
metapneumovirus." Nat Commun,
14, 7627. doi: 10.1038/s41467-023-43434-5.
|
11-mer ring of human metapneumovirus (hmpv) n-RNA .
SNAP output
|
|
8pdn
|
viral protein |
cryo-EM (4.7 Å) |
Whitehead JD, Decool H, Leyrat C, Carrique L, Fix J,
Eleouet JF, Galloux M, Renner M |
(2023) "Structure
of the N-RNA/P interface indicates mode of L/P
recruitment to the nucleocapsid of human
metapneumovirus." Nat Commun,
14, 7627. doi: 10.1038/s41467-023-43434-5.
|
Spiral of assembled human metapneumovirus (hmpv) n-RNA
. SNAP output
|
|
8pdo
|
viral protein |
cryo-EM (3.1 Å) |
Whitehead JD, Decool H, Leyrat C, Carrique L, Fix J,
Eleouet JF, Galloux M, Renner M |
(2023) "Structure
of the N-RNA/P interface indicates mode of L/P
recruitment to the nucleocapsid of human
metapneumovirus." Nat Commun,
14, 7627. doi: 10.1038/s41467-023-43434-5.
|
Local refinement of dimeric human metapneumovirus
(hmpv) n-RNA . SNAP
output
|
|
8pdp
|
viral protein |
cryo-EM (2.9 Å) |
Whitehead JD, Decool H, Leyrat C, Carrique L, Fix J,
Eleouet JF, Galloux M, Renner M |
(2023) "Structure
of the N-RNA/P interface indicates mode of L/P
recruitment to the nucleocapsid of human
metapneumovirus." Nat Commun,
14, 7627. doi: 10.1038/s41467-023-43434-5.
|
10-mer ring of hmpv n-RNA bound to the c-terminal
region of p . SNAP
output
|
|
8pdq
|
viral protein |
cryo-EM (3.1 Å) |
Whitehead JD, Decool H, Leyrat C, Carrique L, Fix J,
Eleouet JF, Galloux M, Renner M |
(2023) "Structure
of the N-RNA/P interface indicates mode of L/P
recruitment to the nucleocapsid of human
metapneumovirus." Nat Commun,
14, 7627. doi: 10.1038/s41467-023-43434-5.
|
11-mer ring of hmpv n-RNA bound to the c-terminal
region of p . SNAP
output
|
|
8pdr
|
viral protein |
cryo-EM (4.0 Å) |
Whitehead JD, Decool H, Leyrat C, Carrique L, Fix J,
Eleouet JF, Galloux M, Renner M |
(2023) "Structure
of the N-RNA/P interface indicates mode of L/P
recruitment to the nucleocapsid of human
metapneumovirus." Nat Commun,
14, 7627. doi: 10.1038/s41467-023-43434-5.
|
Rigid body fit of assembled hmpv n-RNA spiral bound to
the c-terminal region of p . SNAP output
|
|
8pds
|
viral protein |
cryo-EM (2.9 Å) |
Whitehead JD, Decool H, Leyrat C, Carrique L, Fix J,
Eleouet JF, Galloux M, Renner M |
(2023) "Structure
of the N-RNA/P interface indicates mode of L/P
recruitment to the nucleocapsid of human
metapneumovirus." Nat Commun,
14, 7627. doi: 10.1038/s41467-023-43434-5.
|
Local refinement of dimeric hmpv n-RNA bound to the
c-terminal region of p . SNAP output
|
|
8pe3
|
RNA binding protein |
X-ray (1.96 Å) |
McQuarrie S, Athukoralage JS, McMahon SA, Graham S,
Ackermann K, Bode BE, White MF, Gloster TM |
(2023) "Activation
of Csm6 ribonuclease by cyclic nucleotide binding: in
an emergency, twist to open." Nucleic Acids
Res., 51, 10590-10605. doi:
10.1093/nar/gkad739.
|
Structure of csm6' from streptococcus thermophilus in
complex with cyclic hexa-adenylate (ca6) . SNAP output
|
|
8peg
|
ribosome |
cryo-EM (3.3 Å) |
Flugel T, Schacherl M, Unbehaun A, Schroeer B,
Dabrowski M, Burger J, Mielke T, Sprink T, Diebolder CA,
Guillen Schlippe YV, Spahn CMT |
(2024) "Transient
disome complex formation in native polysomes during
ongoing protein synthesis captured by cryo-EM."
Nat Commun, 15, 1756. doi:
10.1038/s41467-024-46092-3.
|
Escherichia coli paused disome complex (queueing 70s
non-rotated closed pre state) . SNAP output
|
|
8pfr
|
ribosome |
cryo-EM (2.15 Å) |
Banerjee A, Ataman M, Smialek MJ, Mookherjee D, Rabl
J, Mironov A, Mues L, Enkler L, Coto-Llerena M, Schmidt
A, Boehringer D, Piscuoglio S, Spang A, Mittal N, Zavolan
M |
(2024) "Ribosomal
protein RPL39L is an efficiency factor in the
cotranslational folding of a subset of proteins with
alpha helical domains." Nucleic Acids
Res., 52, 9028-9048. doi:
10.1093/nar/gkae630.
|
Mouse rpl39l integrated into the yeast 60s ribosomal
subunit . SNAP
output
|
|
8phj
|
ribosome |
cryo-EM (3.67 Å) |
Mogila I, Tamulaitiene G, Keda K, Timinskas A,
Ruksenaite A, Sasnauskas G, Venclovas C, Siksnys V,
Tamulaitis G |
(2023) "Ribosomal
stalk-captured CARF-RelE ribonuclease inhibits
translation following CRISPR signaling."
Science, 382, 1036-1041. doi:
10.1126/science.adj2107.
|
Ca4-bound cami1 in complex with 70s ribosome . SNAP output
|
|
8pjb
|
RNA binding protein |
cryo-EM (3.62 Å) |
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K,
Beck M, Becker PB, Hennig J |
(2023) "Structural
basis of RNA-induced autoregulation of the DExH-type
RNA helicase maleless." Mol.Cell,
83, 4318-4333.e10. doi: 10.1016/j.molcel.2023.10.026.
|
cryo-EM structure of mle in complex with uuc RNA and
adp . SNAP output
|
|
8pjj
|
RNA binding protein |
cryo-EM (4.24 Å) |
Jagtap PKA, Muller M, Kiss AE, Thomae AW, Lapouge K,
Beck M, Becker PB, Hennig J |
(2023) "Structural
basis of RNA-induced autoregulation of the DExH-type
RNA helicase maleless." Mol.Cell,
83, 4318-4333.e10. doi: 10.1016/j.molcel.2023.10.026.
|
cryo-EM structure of mle in complex with sl7uuc RNA and
adp . SNAP output
|
|
8pk0
|
ribosome |
cryo-EM (3.03 Å) |
Nguyen TG, Ritter C, Kummer E |
(2023) "Structural
insights into the role of GTPBP10 in the RNA maturation
of the mitoribosome." Nat Commun,
14, 7991. doi: 10.1038/s41467-023-43599-z.
|
Human mitoribosomal large subunit assembly intermediate
1 with gtpbp10-gtpbp7 . SNAP output
|
|
8pkl
|
ribosome |
cryo-EM (3.09 Å) |
Flugel T, Schacherl M, Unbehaun A, Schroeer B,
Dabrowski M, Burger J, Mielke T, Sprink T, Diebolder CA,
Guillen Schlippe YV, Spahn CMT |
(2024) "Transient
disome complex formation in native polysomes during
ongoing protein synthesis captured by cryo-EM."
Nat Commun, 15, 1756. doi:
10.1038/s41467-024-46092-3.
|
Escherichia coli paused disome complex (leading 70s
non-rotated closed pre state) . SNAP output
|
|
8pm0
|
viral protein |
cryo-EM (2.9 Å) |
Krischuns T, Arragain B, Isel C, Paisant S, Budt M,
Wolff T, Cusack S, Naffakh N |
(2024) "The host
RNA polymerase II C-terminal domain is the anchor for
replication of the influenza virus genome." Nat
Commun, 15, 1064. doi: 10.1038/s41467-024-45205-2.
|
Influenza a-h7n9 polymerase in replicase-like
conformation in pre-initiation state with pol ii ps5
ctd peptide mimic bound in site 1a-2a . SNAP output
|
|
8pnf
|
virus |
cryo-EM (2.9 Å) |
Gil-Cantero D, Mata CP, Valiente L, Rodriguez-Huete
A, Valbuena A, Twarock R, Stockley PG, Mateu MG, Caston
JR |
(2024) "Cryo-EM
of human rhinovirus reveals capsid-RNA duplex
interactions that provide insights into virus assembly
and genome uncoating." Commun Biol,
7, 1501. doi: 10.1038/s42003-024-07213-2.
|
Hrv b14 virion proteins . SNAP output
|
|
8pnn
|
ribosome |
X-ray (2.9 Å) |
Terrosu S, Nurullina L, Supantanapong N, Pak BS,
Nguyen S, Holm M, Wu C, Lin M, Horne D, Sachs MS,
Blanchard SC, Yusupov M, Vanderwal CD |
(2025) "Synthesis
of Differentially Halogenated Lissoclimide Analogues To
Probe Ribosome E-Site Binding." Acs
Chem.Biol., 20, 858-869. doi:
10.1021/acschembio.4c00825.
|
80s yeast ribosome in complex with bromolissoclimide .
SNAP output
|
|
8pnp
|
viral protein |
cryo-EM (2.49 Å) |
Krischuns T, Arragain B, Isel C, Paisant S, Budt M,
Wolff T, Cusack S, Naffakh N |
(2024) "The host
RNA polymerase II C-terminal domain is the anchor for
replication of the influenza virus genome." Nat
Commun, 15, 1064. doi: 10.1038/s41467-024-45205-2.
|
Influenza a-h7n9 polymerase in pre-initiation state
with continuous pol ii ps5 ctd peptide mimic bound in
site 1a-2a . SNAP
output
|
|
8pnq
|
viral protein |
cryo-EM (2.88 Å) |
Krischuns T, Arragain B, Isel C, Paisant S, Budt M,
Wolff T, Cusack S, Naffakh N |
(2024) "The host
RNA polymerase II C-terminal domain is the anchor for
replication of the influenza virus genome." Nat
Commun, 15, 1064. doi: 10.1038/s41467-024-45205-2.
|
Influenza a-h7n9 polymerase in elongation state with
continuous pol ii ps5 ctd peptide mimic bound in site
1a-2a . SNAP output
|
|
8poh
|
viral protein |
cryo-EM (3.3 Å) |
Krischuns T, Arragain B, Isel C, Paisant S, Budt M,
Wolff T, Cusack S, Naffakh N |
(2024) "The host
RNA polymerase II C-terminal domain is the anchor for
replication of the influenza virus genome." Nat
Commun, 15, 1064. doi: 10.1038/s41467-024-45205-2.
|
Influenza a-h7n9 polymerase symmetric dimer bound to
the promoter (pa k289a-c489r) . SNAP output
|
|
8pot
|
ligase |
X-ray (2.149 Å) |
Hoffmann G, Lukarska M, Clare RH, Masters EKG,
Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ,
Jensen MR, Palencia A |
(2024) "Targeting
a microbiota Wolbachian aminoacyl-tRNA synthetase to
block its pathogenic host." Sci Adv,
10, eado1453. doi: 10.1126/sciadv.ado1453.
|
Ternary complex of e. coli leucyl-trna synthetase,
trna(leu) and the benzoxaborole cmpd9 in the editing
conformation . SNAP
output
|
|
8ppk
|
translation |
cryo-EM (2.98 Å) |
Schubert K, Karousis ED, Ban I, Lapointe CP,
Leibundgut M, Baumlin E, Kummerant E, Scaiola A, Schonhut
T, Ziegelmuller J, Puglisi JD, Muhlemann O, Ban N |
(2023) "Universal
features of Nsp1-mediated translational shutdown by
coronaviruses." Mol.Cell,
83, 3546-3557.e8. doi: 10.1016/j.molcel.2023.09.002.
|
Bat-hp-cov nsp1 and eif1 bound to the human 40s small
ribosomal subunit . SNAP
output
|
|
8ppl
|
translation |
cryo-EM (2.65 Å) |
Schubert K, Karousis ED, Ban I, Lapointe CP,
Leibundgut M, Baumlin E, Kummerant E, Scaiola A, Schonhut
T, Ziegelmuller J, Puglisi JD, Muhlemann O, Ban N |
(2023) "Universal
features of Nsp1-mediated translational shutdown by
coronaviruses." Mol.Cell,
83, 3546-3557.e8. doi: 10.1016/j.molcel.2023.09.002.
|
Mers-cov nsp1 bound to the human 43s pre-initiation
complex . SNAP
output
|
|
8psn
|
viral protein |
cryo-EM (2.73 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna initiation state
(transcriptase conformation) . SNAP output
|
|
8pso
|
viral protein |
cryo-EM (2.4 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna initiation state
(core only) . SNAP
output
|
|
8psq
|
viral protein |
cryo-EM (2.65 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in crna pre-initiation
state mode a (core only) . SNAP output
|
|
8pss
|
viral protein |
cryo-EM (2.83 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in crna pre-initiation
state mode b (core-endo only) . SNAP output
|
|
8psu
|
viral protein |
cryo-EM (3.18 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna pre-initiation
state mode a (core only) . SNAP output
|
|
8psx
|
viral protein |
cryo-EM (2.96 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna elongation state
(transcriptase conformation) . SNAP output
|
|
8psz
|
viral protein |
cryo-EM (2.42 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna elongation state
with additional mode b promoter (transcriptase
conformation) . SNAP
output
|
|
8pt2
|
viral protein |
cryo-EM (2.59 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna pre-initiation
state mode b (transcriptase conformation) . SNAP output
|
|
8pt6
|
viral protein |
cryo-EM (3.03 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna initiation state
(replicase conformation) . SNAP output
|
|
8pt7
|
viral protein |
cryo-EM (2.8 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in crna pre-initiation
state mode a (core-endo only) . SNAP output
|
|
8ptg
|
transcription |
cryo-EM (2.9 Å) |
Said N, Finazzo M, Hilal T, Wang B, Selinger TL,
Gjorgjevikj D, Artsimovitch I, Wahl MC |
(2024) "Sm-like
protein Rof inhibits transcription termination factor
rho by binding site obstruction and conformational
insulation." Nat Commun,
15, 3186. doi: 10.1038/s41467-024-47439-6.
|
Structure of the transcription termination factor rho
bound to RNA at the pbs and sbs . SNAP output
|
|
8pth
|
viral protein |
cryo-EM (2.73 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna pre-initiation
state mode b (open core | partial replicase
conformation) . SNAP
output
|
|
8ptj
|
viral protein |
cryo-EM (2.86 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna pre-initiation
state mode b (close core | partial replicase
conformation) . SNAP
output
|
|
8ptx
|
translation |
cryo-EM (2.87 Å) |
Abbassi NE, Jaciuk M, Scherf D, Bohnert P, Rau A,
Hammermeister A, Rawski M, Indyka P, Wazny G,
Chramiec-Glabik A, Dobosz D, Skupien-Rabian B, Jankowska
U, Rappsilber J, Schaffrath R, Lin TY, Glatt S |
(2024) "Cryo-EM
structures of the human Elongator complex at work."
Nat Commun, 15, 4094. doi:
10.1038/s41467-024-48251-y.
|
cryo-EM structure of human elp123 in complex with trna,
acetyl-coa, 5'-deoxyadenosine and methionine . SNAP output
|
|
8ptz
|
translation |
cryo-EM (3.35 Å) |
Abbassi NE, Jaciuk M, Scherf D, Bohnert P, Rau A,
Hammermeister A, Rawski M, Indyka P, Wazny G,
Chramiec-Glabik A, Dobosz D, Skupien-Rabian B, Jankowska
U, Rappsilber J, Schaffrath R, Lin TY, Glatt S |
(2024) "Cryo-EM
structures of the human Elongator complex at work."
Nat Commun, 15, 4094. doi:
10.1038/s41467-024-48251-y.
|
cryo-EM structure of human elp123 in complex with trna,
s-ethyl-coa, 5'-deoxyadenosine and methionine .
SNAP output
|
|
8pu0
|
translation |
cryo-EM (4.25 Å) |
Abbassi NE, Jaciuk M, Scherf D, Bohnert P, Rau A,
Hammermeister A, Rawski M, Indyka P, Wazny G,
Chramiec-Glabik A, Dobosz D, Skupien-Rabian B, Jankowska
U, Rappsilber J, Schaffrath R, Lin TY, Glatt S |
(2024) "Cryo-EM
structures of the human Elongator complex at work."
Nat Commun, 15, 4094. doi:
10.1038/s41467-024-48251-y.
|
cryo-EM structure of human elp123 in complex with trna,
desulpho-coa, 5'-deoxyadenosine and methionine .
SNAP output
|
|
8pv1
|
ribosome |
cryo-EM (2.56 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 6 - pre-5s
rotation - l1 intermediate - composite structure .
SNAP output
|
|
8pv2
|
ribosome |
cryo-EM (2.63 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 10 - pre-5s
rotation with ytm1-erb1 . SNAP output
|
|
8pv3
|
ribosome |
cryo-EM (2.8 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 9 - pre-5s
rotation - immature h68-h69 - composite structure .
SNAP output
|
|
8pv4
|
ribosome |
cryo-EM (2.9 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 2 - pre-5s
rotation with rix1 complex - composite structure .
SNAP output
|
|
8pv5
|
ribosome |
cryo-EM (2.86 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 8 - pre-5s
rotation without foot - composite structure . SNAP output
|
|
8pv6
|
ribosome |
cryo-EM (2.94 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 3 - post-5s
rotation with rix1 complex with foot - composite
structure . SNAP
output
|
|
8pv7
|
ribosome |
cryo-EM (2.12 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 1 - pre-5s
rotation (arx1-nog2 state) - composite structure .
SNAP output
|
|
8pv8
|
ribosome |
cryo-EM (2.91 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 4 - post-5s
rotation with rix1 complex without foot - composite
structure . SNAP
output
|
|
8pva
|
ribosome |
cryo-EM (4.5 Å) |
McMullan G, Naydenova K, Mihaylov D, Yamashita K,
Peet MJ, Wilson H, Dickerson JL, Chen S, Cannone G, Lee
Y, Hutchings KA, Gittins O, Sobhy MA, Wells T, El-Gomati
MM, Dalby J, Meffert M, Schulze-Briese C, Henderson R,
Russo CJ |
(2023) "Structure
determination by cryoEM at 100 keV."
Proc.Natl.Acad.Sci.USA, 120,
e2312905120. doi: 10.1073/pnas.2312905120.
|
Structure of bacterial ribosome determined by cryoem at
100 kev . SNAP
output
|
|
8pvk
|
ribosome |
cryo-EM (2.55 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 5 - pre-5s
rotation - l1 inward - composite structure . SNAP output
|
|
8pvl
|
ribosome |
cryo-EM (2.19 Å) |
Thoms M, Lau B, Cheng J, Fromm L, Denk T, Kellner N,
Flemming D, Fischer P, Falquet L, Berninghausen O,
Beckmann R, Hurt E |
(2023) "Structural
insights into coordinating 5S RNP rotation with ITS2
pre-RNA processing during ribosome formation."
Embo Rep., 24, e57984. doi:
10.15252/embr.202357984.
|
Chaetomium thermophilum pre-60s state 7 - pre-5s
rotation lacking utp30-its2 - composite structure .
SNAP output
|
|
8pxs
|
unknown function |
NMR |
Rout SK, Cadalbert R, Schroder N, Wang J, Zehnder J,
Gampp O, Wiegand T, Guntert P, Klingler D, Kreutz C,
Knorlein A, Hall J, Greenwald J, Riek R |
(2023) "An
Analysis of Nucleotide-Amyloid Interactions Reveals
Selective Binding to Codon-Sized RNA."
J.Am.Chem.Soc., 145,
21915-21924. doi: 10.1021/jacs.3c06287.
|
Short RNA binding to peptide amyloids . SNAP output
|
|
8q3z
|
DNA binding protein |
X-ray (3.15 Å) |
Jungfer K, Sigg A, Jinek M |
(2024) "Substrate
selectivity and catalytic activation of the type III
CRISPR ancillary nuclease Can2." Nucleic Acids
Res., 52, 462-473. doi: 10.1093/nar/gkad1102.
|
Crystal structure of ca4-bound can2 from
thermoanaerobacter brockii . SNAP output
|
|
8q4f
|
ribosome |
cryo-EM (3.1 Å) |
Majumdar S, Parajuli NP, Ge X, Emmerich A, Sanyal
S |
"Structure of arbekacin bound Escherichia coli 70S
ribosome." |
Structure of arbekacin bound escherichia coli 70s
ribosome . SNAP
output
|
|
8q5i
|
ribosome |
cryo-EM (2.45 Å) |
Kolosova O, Zgadzay Y, Stetsenko A, Atamas A, Wu C,
Jenner L, Sachs SM, Guskov A, Yusupov M |
(2023) "Structural characterization of cephaeline
binding to the eukaryotic ribosome using Cryo-Electron
Microscopy." Biopolym Cell. doi: 10.7124/bc.000AA4.
|
Structure of candida albicans 80s ribosome in complex
with cephaeline . SNAP
output
|
|
8q7n
|
splicing |
cryo-EM (3.1 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Urlaub H, Stark
H, Luhrmann R |
(2024) "Cryo-EM
analyses of dimerized spliceosomes provide new insights
into the functions of B complex proteins." Embo
J., 43, 1065-1088. doi: 10.1038/s44318-024-00052-1.
|
cryo-EM structure of the human spliceosomal b complex
protomer (tri-snrnp core region) . SNAP output
|
|
8q7q
|
splicing |
cryo-EM (3.2 Å) |
Riabov Bassat D, Visanpattanasin S, Vorlander MK, Fin
L, Phillips AW, Plaschka C |
(2024) "Structural
basis of human U5 snRNP late biogenesis and
recycling." Nat.Struct.Mol.Biol.,
31, 747-751. doi: 10.1038/s41594-024-01243-4.
|
Structure of the recycling u5 snrnp bound to chaperones
cd2bp2 and tssc4 (state 2) . SNAP output
|
|
8q7v
|
splicing |
cryo-EM (3.8 Å) |
Riabov Bassat D, Visanpattanasin S, Vorlander MK, Fin
L, Phillips AW, Plaschka C |
(2024) "Structural
basis of human U5 snRNP late biogenesis and
recycling." Nat.Struct.Mol.Biol.,
31, 747-751. doi: 10.1038/s41594-024-01243-4.
|
Structure of the recycling u5 snrnp bound to chaperones
cd2bp2 and tssc4 (state 1) . SNAP output
|
|
8q7w
|
splicing |
cryo-EM (3.9 Å) |
Riabov Bassat D, Visanpattanasin S, Vorlander MK, Fin
L, Phillips AW, Plaschka C |
(2024) "Structural
basis of human U5 snRNP late biogenesis and
recycling." Nat.Struct.Mol.Biol.,
31, 747-751. doi: 10.1038/s41594-024-01243-4.
|
Structure of the recycling u5 snrnp bound to chaperone
cd2bp2 (state 3) . SNAP
output
|
|
8q7x
|
splicing |
cryo-EM (4.6 Å) |
Riabov Bassat D, Visanpattanasin S, Vorlander MK, Fin
L, Phillips AW, Plaschka C |
(2024) "Structural
basis of human U5 snRNP late biogenesis and
recycling." Nat.Struct.Mol.Biol.,
31, 747-751. doi: 10.1038/s41594-024-01243-4.
|
Structure of the recycling u5 snrnp bound to chaperone
cd2bp2 (state 4) . SNAP
output
|
|
8q7z
|
ribosome |
cryo-EM (2.5 Å) |
Nurullina L, Terrosu S, Myasnikov AG, Jenner LB,
Yusupov M |
(2024) "Cryo-EM
structure of the inactive ribosome complex accumulated
in chick embryo cells in cold-stress conditions."
Febs Lett., 598, 537-547.
doi: 10.1002/1873-3468.14831.
|
Structure of the g. gallus 80s non-rotated ribosome .
SNAP output
|
|
8q87
|
ribosome |
cryo-EM (2.4 Å) |
Nurullina L, Terrosu S, Myasnikov AG, Jenner LB,
Yusupov M |
(2024) "Cryo-EM
structure of the inactive ribosome complex accumulated
in chick embryo cells in cold-stress conditions."
Febs Lett., 598, 537-547.
doi: 10.1002/1873-3468.14831.
|
Structure of the g. gallus 80s rotated ribosome in
complex with eef2 and serbp1 . SNAP output
|
|
8q91
|
splicing |
cryo-EM (3.1 Å) |
Schneider S, Brandina I, Peter D, Lagad S, Fraudeau
A, Portell-Montserrat J, Tholen J, Zhao J, Galej WP |
(2024) "Structure
of the human 20S U5 snRNP."
Nat.Struct.Mol.Biol., 31,
752-756. doi: 10.1038/s41594-024-01250-5.
|
Structure of the human 20s u5 snrnp core . SNAP output
|
|
8q9t
|
hydrolase |
cryo-EM (2.84 Å) |
Keidel A, Kogel A, Reichelt P, Kowalinski E, Schafer
IB, Conti E |
(2023) "Concerted
structural rearrangements enable RNA channeling into
the cytoplasmic Ski238-Ski7-exosome assembly."
Mol.Cell, 83, 4093-4105.e7.
doi: 10.1016/j.molcel.2023.09.037.
|
Cryoem structure of a s. cerevisiae ski238 complex
bound to RNA . SNAP
output
|
|
8qbt
|
ribosome |
cryo-EM (2.2 Å) |
Morici M, Gabrielli S, Fujiwara K, Paternoga H,
Beckert B, Bock LV, Chiba S, Wilson DN |
(2024) "RAPP-containing
arrest peptides induce translational stalling by short
circuiting the ribosomal peptidyltransferase
activity." Nat Commun,
15, 2432. doi: 10.1038/s41467-024-46761-3.
|
E. coli apdp-stalled ribosomal complex . SNAP output
|
|
8qca
|
hydrolase |
cryo-EM (2.84 Å) |
Keidel A, Kogel A, Reichelt P, Kowalinski E, Schafer
IB, Conti E |
(2023) "Concerted
structural rearrangements enable RNA channeling into
the cytoplasmic Ski238-Ski7-exosome assembly."
Mol.Cell, 83, 4093. doi:
10.1016/j.molcel.2023.09.037.
|
Cryoem structure of a s. cerevisiae ski2387 complex in
the closed state bound to RNA . SNAP output
|
|
8qcf
|
hydrolase |
cryo-EM (2.55 Å) |
Keidel A, Kogel A, Reichelt P, Kowalinski E, Schafer
IB, Conti E |
(2023) "Concerted
structural rearrangements enable RNA channeling into
the cytoplasmic Ski238-Ski7-exosome assembly."
Mol.Cell, 83, 4093-4105.e7.
doi: 10.1016/j.molcel.2023.09.037.
|
Yeast cytoplasmic exosome-ski2 complex degrading a RNA
substrate . SNAP
output
|
|
8qcq
|
ribosome |
cryo-EM (2.3 Å) |
Morici M, Gabrielli S, Fujiwara K, Paternoga H,
Beckert B, Bock LV, Chiba S, Wilson DN |
(2024) "RAPP-containing
arrest peptides induce translational stalling by short
circuiting the ribosomal peptidyltransferase
activity." Nat Commun,
15, 2432. doi: 10.1038/s41467-024-46761-3.
|
B. subtilis apda-stalled ribosomal complex . SNAP output
|
|
8qeq
|
transcription |
cryo-EM (3.1 Å) |
Tluckova K, Kaczmarek B, Salmazo A, Bernecky C |
(2025) "Mechanism
of mammalian transcriptional repression by noncoding
RNA." Nat.Struct.Mol.Biol.,
32, 607-612. doi: 10.1038/s41594-024-01448-7.
|
RNA polymerase ii bound to minimal alu RNA right arm in
the alternative conformation . SNAP output
|
|
8qfd
|
ligase |
cryo-EM (2.2 Å) |
Makhlouf L, Peter JJ, Magnussen HM, Thakur R,
Millrine D, Minshull TC, Harrison G, Varghese J,
Lamoliatte F, Foglizzo M, Macartney T, Calabrese AN,
Zeqiraj E, Kulathu Y |
(2024) "The UFM1
E3 ligase recognizes and releases 60S ribosomes from ER
translocons." Nature,
627, 437-444. doi: 10.1038/s41586-024-07093-w.
|
Ufl1 e3 ligase bound 60s ribosome . SNAP output
|
|
8qfs
|
RNA binding protein |
cryo-EM (2.7 Å) |
Sharma R, Adams M, Griffith-Jones S, Sahr T,
Gomez-Valero L, Weis F, Hons M, Gharbi S, Berkane R,
Stolz A, Buchrieser C, Bhogaraju S |
(2023) "Structural
basis for the toxicity of Legionella pneumophila
effector SidH." Nat Commun,
14, 7068. doi: 10.1038/s41467-023-42683-8.
|
cryo-EM structure of sidh from legionella pneumophila .
SNAP output
|
|
8qgt
|
viral protein |
cryo-EM (2.8 Å) |
Durieux Trouilleton Q, Housset D, Tarillon P,
Arragain B, Malet H |
(2024) "Structural
characterization of the oligomerization of full-length
Hantaan virus polymerase into symmetric dimers and
hexamers." Nat Commun,
15, 2256. doi: 10.1038/s41467-024-46601-4.
|
5'vrna-bound hantaan virus polymerase in monomeric
intermediate state . SNAP output
|
|
8qh3
|
viral protein |
cryo-EM (2.81 Å) |
Durieux Trouilleton Q, Housset D, Tarillon P,
Arragain B, Malet H |
(2024) "Structural
characterization of the oligomerization of full-length
Hantaan virus polymerase into symmetric dimers and
hexamers." Nat Commun,
15, 2256. doi: 10.1038/s41467-024-46601-4.
|
5'vrna-bound hantaan virus polymerase in monomeric
active state . SNAP
output
|
|
8qhc
|
RNA binding protein |
cryo-EM (3.1 Å) |
Sharma R, Adams M, Griffith-Jones S, Sahr T,
Gomez-Valero L, Weis F, Hons M, Gharbi S, Berkane R,
Stolz A, Buchrieser C, Bhogaraju S |
(2023) "Structural
basis for the toxicity of Legionella pneumophila
effector SidH." Nat Commun,
14, 7068. doi: 10.1038/s41467-023-42683-8.
|
cryo-EM structure of sidh from legionella pneumophila
in complex with lubx . SNAP output
|
|
8qhu
|
ribosome |
cryo-EM (2.72 Å) |
Rajan KS, Yonath A, Bashan A |
"CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME :
LM32Cs1C1 snoRNA overexpression." |
cryo-EM structure of leishmania major 80s ribosome :
lm32cs1c1 snorna overexpression . SNAP output
|
|
8qie
|
ribosome |
cryo-EM (2.43 Å) |
Rajan KS, Yonath A, Bashan A |
"CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME :
LM32Cs1C1 mutant snoRNA overexpression, class 4." |
cryo-EM structure of leishmania major 80s ribosome :
lm32cs1c1 mutant snorna overexpression, class 4 .
SNAP output
|
|
8qjk
|
gene regulation |
X-ray (1.761 Å) |
Gruschow S, McQuarrie S, Ackermann K, McMahon S, Bode
BE, Gloster TM, White MF |
(2024) "CRISPR
antiphage defence mediated by the cyclic
nucleotide-binding membrane protein Csx23."
Nucleic Acids Res., 52,
2761-2775. doi: 10.1093/nar/gkae167.
|
Structure of the cytoplasmic domain of csx23 from
vibrio cholera in complex with cyclic tetra-adenylate
(ca4) . SNAP output
|
|
8qk7
|
ribosome |
cryo-EM (2.77 Å) |
Pundir S, Larsson DSD, Selmer M, Sanyal S |
"The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of RF1 in
bacteria." |
E167k rf2 on e. coli 70s release complex with uaa .
SNAP output
|
|
8qo9
|
splicing |
cryo-EM (5.29 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Urlaub H, Stark
H, Luhrmann R |
(2024) "Cryo-EM
analyses of dimerized spliceosomes provide new insights
into the functions of B complex proteins." Embo
J., 43, 1065-1088. doi: 10.1038/s44318-024-00052-1.
|
cryo-EM structure of a human spliceosomal b complex
protomer . SNAP
output
|
|
8qoa
|
ribosome |
cryo-EM (2.0 Å) |
Gersteuer F, Morici M, Gabrielli S, Fujiwara K,
Safdari HA, Paternoga H, Bock LV, Chiba S, Wilson DN |
(2024) "The SecM
arrest peptide traps a pre-peptide bond formation state
of the ribosome." Nat Commun,
15, 2431. doi: 10.1038/s41467-024-46762-2.
|
Structure of secm-stalled escherichia coli 70s ribosome
. SNAP output
|
|
8qoz
|
splicing |
cryo-EM (3.1 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of pre-b+5'ss+atpgammas complex (core
part) . SNAP output
|
|
8qp8
|
splicing |
cryo-EM (3.5 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of pre-b complex (core part) .
SNAP output
|
|
8qp9
|
splicing |
cryo-EM (4.1 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of pre-b+amppnp complex (core part) .
SNAP output
|
|
8qpa
|
splicing |
cryo-EM (3.7 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of pre-b+5'sslng complex (core part)
. SNAP output
|
|
8qpb
|
splicing |
cryo-EM (3.7 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of pre-b+atp complex (core part) .
SNAP output
|
|
8qpe
|
splicing |
cryo-EM (3.1 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of pre-b-like complex (core part) .
SNAP output
|
|
8qpk
|
splicing |
cryo-EM (4.2 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of pre-b+5'ss complex (core part) .
SNAP output
|
|
8qpp
|
ribosome |
cryo-EM (3.4 Å) |
Park EN, Mackens-Kiani T, Berhane R, Esser H,
Erdenebat C, Burroughs AM, Berninghausen O, Aravind L,
Beckmann R, Green R, Buskirk AR |
(2024) "B.
subtilis MutS2 splits stalled ribosomes into subunits
without mRNA cleavage." Embo J.,
43, 484-506. doi: 10.1038/s44318-023-00010-3.
|
Bacillus subtilis muts2-collided disome complex
(stalled 70s) . SNAP
output
|
|
8qrk
|
ribosome |
cryo-EM (6.69 Å) |
Cipullo M, Valentin Gese G, Gopalakrishna S, Krueger
A, Lobo V, Pirozhkova MA, Marks J, Palenikova P, Shiriaev
D, Liu Y, Misic J, Cai Y, Nguyen MD, Abdelbagi A, Li X,
Minczuk M, Hafner M, Benhalevy D, Sarshad AA, Atanassov
I, Hallberg BM, Rorbach J |
(2024) "GTPBP8
plays a role in mitoribosome formation in human
mitochondria." Nat Commun,
15, 5664. doi: 10.1038/s41467-024-50011-x.
|
Mt-ssu assembly intermediate in gtpbp8 knock-out cells,
state 1 . SNAP
output
|
|
8qrl
|
ribosome |
cryo-EM (3.34 Å) |
Cipullo M, Valentin Gese G, Gopalakrishna S, Krueger
A, Lobo V, Pirozhkova MA, Marks J, Palenikova P, Shiriaev
D, Liu Y, Misic J, Cai Y, Nguyen MD, Abdelbagi A, Li X,
Minczuk M, Hafner M, Benhalevy D, Sarshad AA, Atanassov
I, Hallberg BM, Rorbach J |
(2024) "GTPBP8
plays a role in mitoribosome formation in human
mitochondria." Nat Commun,
15, 5664. doi: 10.1038/s41467-024-50011-x.
|
Mt-ssu assembly intermediate in gtpbp8 knock-out cells,
state 2 . SNAP
output
|
|
8qrm
|
ribosome |
cryo-EM (3.05 Å) |
Cipullo M, Valentin Gese G, Gopalakrishna S, Krueger
A, Lobo V, Pirozhkova MA, Marks J, Palenikova P, Shiriaev
D, Liu Y, Misic J, Cai Y, Nguyen MD, Abdelbagi A, Li X,
Minczuk M, Hafner M, Benhalevy D, Sarshad AA, Atanassov
I, Hallberg BM, Rorbach J |
(2024) "GTPBP8
plays a role in mitoribosome formation in human
mitochondria." Nat Commun,
15, 5664. doi: 10.1038/s41467-024-50011-x.
|
Mt-ssu assembly intermediate in gtpbp8 knock-out cells,
state 3 . SNAP
output
|
|
8qrn
|
ribosome |
cryo-EM (2.98 Å) |
Cipullo M, Valentin Gese G, Gopalakrishna S, Krueger
A, Lobo V, Pirozhkova MA, Marks J, Palenikova P, Shiriaev
D, Liu Y, Misic J, Cai Y, Nguyen MD, Abdelbagi A, Li X,
Minczuk M, Hafner M, Benhalevy D, Sarshad AA, Atanassov
I, Hallberg BM, Rorbach J |
(2024) "GTPBP8
plays a role in mitoribosome formation in human
mitochondria." Nat Commun,
15, 5664. doi: 10.1038/s41467-024-50011-x.
|
Mt-ssu in gtpbp8 knock-out cells, state 4 . SNAP output
|
|
8qsj
|
ribosome |
cryo-EM (3.0 Å) |
Nguyen TG, Ritter C, Kummer E |
(2023) "Structural
insights into the role of GTPBP10 in the RNA maturation
of the mitoribosome." Nat Commun,
14, 7991. doi: 10.1038/s41467-023-43599-z.
|
Human mitoribosomal large subunit assembly intermediate
2 with gtpbp7 . SNAP
output
|
|
8qu1
|
ribosome |
cryo-EM (2.74 Å) |
Cipullo M, Valentin Gese G, Gopalakrishna S, Krueger
A, Lobo V, Pirozhkova MA, Marks J, Palenikova P, Shiriaev
D, Liu Y, Misic J, Cai Y, Nguyen MD, Abdelbagi A, Li X,
Minczuk M, Hafner M, Benhalevy D, Sarshad AA, Atanassov
I, Hallberg BM, Rorbach J |
(2024) "GTPBP8
plays a role in mitoribosome formation in human
mitochondria." Nat Commun,
15, 5664. doi: 10.1038/s41467-024-50011-x.
|
Mt-lsu assembly intermediate in gtpbp8 knock-out cells,
state 1 . SNAP
output
|
|
8qu5
|
ribosome |
cryo-EM (2.42 Å) |
Cipullo M, Valentin Gese G, Gopalakrishna S, Krueger
A, Lobo V, Pirozhkova MA, Marks J, Palenikova P, Shiriaev
D, Liu Y, Misic J, Cai Y, Nguyen MD, Abdelbagi A, Li X,
Minczuk M, Hafner M, Benhalevy D, Sarshad AA, Atanassov
I, Hallberg BM, Rorbach J |
(2024) "GTPBP8
plays a role in mitoribosome formation in human
mitochondria." Nat Commun,
15, 5664. doi: 10.1038/s41467-024-50011-x.
|
Mt-lsu assembly intermediate in gtpbp8 knock-out cells,
state 2 . SNAP
output
|
|
8qxd
|
splicing |
cryo-EM (9.6 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of the cross-exon pre-b complex .
SNAP output
|
|
8qyx
|
ribosome |
cryo-EM (1.78 Å) |
Wiechert F, Unbehaun A, Sprink T, Seibel H, Burger J,
Loerke J, Mielke T, Diebolder CA, Schacherl M, Spahn
CMT |
(2025) "Visualizing
the modification landscape of the human 60S ribosomal
subunit at close to atomic resolution." Nucleic
Acids Res., 53. doi: 10.1093/nar/gkae1191.
|
Human 60s ribosomal subunit . SNAP output
|
|
8qz8
|
viral protein |
cryo-EM (3.13 Å) |
Arragain B, Pelosse M, Thompson A, Cusack S |
(2023) "Structural
and functional analysis of the minimal
orthomyxovirus-like polymerase of Tilapia Lake Virus
from the highly diverged Amnoonviridae family."
Nat Commun, 14, 8145. doi:
10.1038/s41467-023-44044-x.
|
Tilapia lake virus polymerase in vrna pre-termination
state (transcriptase conformation) . SNAP output
|
|
8qzs
|
splicing |
cryo-EM (4.1 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of the cross-exon b-like complex .
SNAP output
|
|
8r08
|
splicing |
cryo-EM (6.1 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of the cross-exon pre-b+amppnp
complex . SNAP
output
|
|
8r09
|
splicing |
cryo-EM (4.3 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of the cross-exon
pre-b+5'ss+atpgammas complex . SNAP output
|
|
8r0a
|
splicing |
cryo-EM (5.8 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of the cross-exon pre-b+5'ss complex
. SNAP output
|
|
8r0b
|
splicing |
cryo-EM (4.4 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of the cross-exon pre-b+atp complex .
SNAP output
|
|
8r3k
|
viral protein |
cryo-EM (3.43 Å) |
Krischuns T, Arragain B, Isel C, Paisant S, Budt M,
Wolff T, Cusack S, Naffakh N |
(2024) "The host
RNA polymerase II C-terminal domain is the anchor for
replication of the influenza virus genome." Nat
Commun, 15, 1064. doi: 10.1038/s41467-024-45205-2.
|
Influenza a-h7n9 polymerase in self-stalled
pre-termination state, with pol ii ps5 ctd peptide
mimic bound in site 1a-2a. . SNAP output
|
|
8r3l
|
viral protein |
cryo-EM (3.25 Å) |
Krischuns T, Arragain B, Isel C, Paisant S, Budt M,
Wolff T, Cusack S, Naffakh N |
(2024) "The host
RNA polymerase II C-terminal domain is the anchor for
replication of the influenza virus genome." Nat
Commun, 15, 1064. doi: 10.1038/s41467-024-45205-2.
|
Influenza a-h7n9 polymerase in pre-initiation state,
intermediate conformation (i) with pb2-c(i), endo(t),
and pol ii ps5 ctd peptide mimic bound in site 1a-2a .
SNAP output
|
|
8r3v
|
ribosome |
cryo-EM (3.28 Å) |
Flugel T, Schacherl M, Unbehaun A, Schroeer B,
Dabrowski M, Burger J, Mielke T, Sprink T, Diebolder CA,
Guillen Schlippe YV, Spahn CMT |
(2024) "Transient
disome complex formation in native polysomes during
ongoing protein synthesis captured by cryo-EM."
Nat Commun, 15, 1756. doi:
10.1038/s41467-024-46092-3.
|
Escherichia coli paused disome complex (non-rotated
disome interface) . SNAP
output
|
|
8r3z
|
RNA binding protein |
cryo-EM (3.4 Å) |
Bastiaanssen C, Bobadilla Ugarte P, Kim K, Finocchio
G, Feng Y, Anzelon TA, Kostlbacher S, Tamarit D, Ettema
TJG, Jinek M, MacRae IJ, Joo C, Swarts DC, Wu F |
(2024) "RNA-guided
RNA silencing by an Asgard archaeal Argonaute."
Nat Commun, 15, 5499. doi:
10.1038/s41467-024-49452-1.
|
cryo-EM structure of the asgard archaeal argonaute
hrago1 bound to a guide RNA . SNAP output
|
|
8r55
|
ribosome |
cryo-EM (3.57 Å) |
Park EN, Mackens-Kiani T, Berhane R, Esser H,
Erdenebat C, Burroughs AM, Berninghausen O, Aravind L,
Beckmann R, Green R, Buskirk AR |
(2024) "B.
subtilis MutS2 splits stalled ribosomes into subunits
without mRNA cleavage." Embo J.,
43, 484-506. doi: 10.1038/s44318-023-00010-3.
|
Bacillus subtilis muts2-collided disome complex
(collided 70s) . SNAP
output
|
|
8r57
|
ribosome |
cryo-EM (2.55 Å) |
Kravchenko OV, Baymukhametov TN, Afonina ZA,
Vassilenko KS |
(2023) "High-Resolution
Structure and Internal Mobility of a Plant 40S
Ribosomal Subunit." Int J Mol Sci,
24. doi: 10.3390/ijms242417453.
|
Cryoem structure of wheat 40s ribosomal subunit, head
domain . SNAP output
|
|
8r60
|
viral protein |
cryo-EM (3.23 Å) |
Keown J, Baazaoui A, Sebesta M, Stefl R, Carrique L,
Fodor E, Grimes JM |
(2024) "Structural
and functional characterization of the interaction
between the influenza A virus RNA polymerase and the
CTD of host RNA polymerase II." J.Virol.,
98, e0013824. doi: 10.1128/jvi.00138-24.
|
1918 h1n1 viral polymerase heterotrimer in complex with
4 repeat serine-5 phosphorylated polii peptide .
SNAP output
|
|
8r65
|
viral protein |
cryo-EM (4.23 Å) |
Keown J, Baazaoui A, Sebesta M, Stefl R, Carrique L,
Fodor E, Grimes JM |
(2024) "Structural
and functional characterization of the interaction
between the influenza A virus RNA polymerase and the
CTD of host RNA polymerase II." J.Virol.,
98, e0013824. doi: 10.1128/jvi.00138-24.
|
1918 h1n1 viral polymerase heterotrimer in complex with
4 repeat serine-5 phosphorylated polii peptide with
ordered pb2 c-terminal domains . SNAP output
|
|
8r6c
|
ribosome |
cryo-EM (2.2 Å) |
Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov
T, Di Stasi A, Dang T, Mainz A, Raulf K, Crowe-McAuliffe
C, Scocchi M, Mardirossian M, Beckert B, Vazquez-Laslop
N, Mankin A, Sussmuth RD, Wilson DN |
(2024) "Paenilamicins
from the honey bee pathogen Paenibacillus larvae are
context-specific translocation inhibitors of protein
synthesis." Biorxiv. doi: 10.1101/2024.05.21.595107.
|
70s escherichia coli ribosome with paenilamicin b2
bound with a- and p-site trna. . SNAP output
|
|
8r6f
|
ribosome |
cryo-EM (2.34 Å) |
Kravchenko OV, Baymukhametov TN, Afonina ZA,
Vassilenko KS |
(2023) "High-Resolution
Structure and Internal Mobility of a Plant 40S
Ribosomal Subunit." Int J Mol Sci,
24. doi: 10.3390/ijms242417453.
|
Cryoem structure of wheat 40s ribosomal subunit, body
domain . SNAP output
|
|
8r6u
|
viral protein |
cryo-EM (2.98 Å) |
Williams HM, Thorkelsson SR, Vogel D, Busch C,
Milewski M, Cusack S, Grunewald K, Quemin ERJ, Rosenthal
M |
(2024) "Structural
snapshots of phenuivirus cap-snatching and
transcription." Nucleic Acids Res.,
52, 6049-6065. doi: 10.1093/nar/gkae330.
|
Structure of the sftsv l protein in a
transcription-priming state without capped RNA
[transcription-priming (in vitro)] . SNAP output
|
|
8r6w
|
viral protein |
cryo-EM (3.35 Å) |
Williams HM, Thorkelsson SR, Vogel D, Busch C,
Milewski M, Cusack S, Grunewald K, Quemin ERJ, Rosenthal
M |
(2024) "Structural
snapshots of phenuivirus cap-snatching and
transcription." Nucleic Acids Res.,
52, 6049-6065. doi: 10.1093/nar/gkae330.
|
Structure of the sftsv l protein in a
transcription-priming state with bound capped RNA
[transcription-priming] . SNAP output
|
|
8r6y
|
viral protein |
cryo-EM (3.4 Å) |
Williams HM, Thorkelsson SR, Vogel D, Busch C,
Milewski M, Cusack S, Grunewald K, Quemin ERJ, Rosenthal
M |
(2024) "Structural
snapshots of phenuivirus cap-snatching and
transcription." Nucleic Acids Res.,
52, 6049-6065. doi: 10.1093/nar/gkae330.
|
Structure of the sftsv l protein stalled in a
transcription-specific early elongation state with
bound capped RNA [transcription-early-elongation] .
SNAP output
|
|
8r7n
|
splicing |
cryo-EM (3.4 Å) |
Zhao J, Peter D, Brandina I, Liu X, Galej WP |
(2025) "Structural
basis of 5' splice site recognition by the minor
spliceosome." Mol.Cell,
85, 652. doi: 10.1016/j.molcel.2024.12.017.
|
Overall structure of the u11 snrnp . SNAP output
|
|
8r8m
|
ribosome |
cryo-EM (2.4 Å) |
Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov
T, Di Stasi A, Dang T, Mainz A, Raulf K, Crowe-McAuliffe
C, Scocchi M, Mardirossian M, Beckert B, Vazquez-Laslop
N, Mankin A, Sussmuth RD, Wilson DN |
(2024) "Paenilamicins
from the honey bee pathogen Paenibacillus larvae are
context-specific translocation inhibitors of protein
synthesis." Biorxiv. doi: 10.1101/2024.05.21.595107.
|
70s escherichia coli ribosome with paenilamicin b2
bound with hybrid a-p- and hybrid p-e-trna. . SNAP output
|
|
8r8r
|
RNA binding protein |
cryo-EM (2.79 Å) |
Todesca S, Sandmeir F, Keidel A, Conti E |
(2024) "Molecular
basis of human poly(A) polymerase recruitment by
mPSF." Rna, 30, 795-806.
doi: 10.1261/rna.079915.123.
|
cryo-EM structure of the human mpsf with papoa
c-terminus peptide (papoac) . SNAP output
|
|
8ran
|
gene regulation |
cryo-EM (3.25 Å) |
Rengachari S, Hainthaler T, Oberthuer C, Lidschreiber
M, Cramer P |
(2025) "Mechanism
of polyadenylation-independent RNA polymerase II
termination." Nat.Struct.Mol.Biol.,
32, 339-345. doi: 10.1038/s41594-024-01409-0.
|
Structure of sen1-RNA complex . SNAP output
|
|
8rao
|
gene regulation |
cryo-EM (4.4 Å) |
Rengachari S, Hainthaler T, Oberthuer C, Lidschreiber
M, Cramer P |
(2025) "Mechanism
of polyadenylation-independent RNA polymerase II
termination." Nat.Struct.Mol.Biol.,
32, 339-345. doi: 10.1038/s41594-024-01409-0.
|
Structure of sen1-adp.bef3-RNA complex . SNAP output
|
|
8rbj
|
ligase |
X-ray (2.37 Å) |
Koehler S, Kopp J, Peschek J |
"Structure of fungal tRNA ligase in complex with
RNA." |
Structure of fungal trna ligase in complex with RNA .
SNAP output
|
|
8rc0
|
splicing |
cryo-EM (3.2 Å) |
Schneider S, Brandina I, Peter D, Lagad S, Fraudeau
A, Portell-Montserrat J, Tholen J, Zhao J, Galej WP |
(2024) "Structure
of the human 20S U5 snRNP."
Nat.Struct.Mol.Biol., 31,
752-756. doi: 10.1038/s41594-024-01250-5.
|
Structure of the human 20s u5 snrnp . SNAP output
|
|
8rcl
|
ribosome |
cryo-EM (3.49 Å) |
Flugel T, Schacherl M, Unbehaun A, Schroeer B,
Dabrowski M, Burger J, Mielke T, Sprink T, Diebolder CA,
Guillen Schlippe YV, Spahn CMT |
(2024) "Transient
disome complex formation in native polysomes during
ongoing protein synthesis captured by cryo-EM."
Nat Commun, 15, 1756. doi:
10.1038/s41467-024-46092-3.
|
Escherichia coli paused disome complex (non-rotated
disome interface class 1) . SNAP output
|
|
8rcm
|
ribosome |
cryo-EM (3.59 Å) |
Flugel T, Schacherl M, Unbehaun A, Schroeer B,
Dabrowski M, Burger J, Mielke T, Sprink T, Diebolder CA,
Guillen Schlippe YV, Spahn CMT |
(2024) "Transient
disome complex formation in native polysomes during
ongoing protein synthesis captured by cryo-EM."
Nat Commun, 15, 1756. doi:
10.1038/s41467-024-46092-3.
|
Escherichia coli paused disome complex (non-rotated
disome interface class 2) . SNAP output
|
|
8rcs
|
ribosome |
cryo-EM (4.46 Å) |
Flugel T, Schacherl M, Unbehaun A, Schroeer B,
Dabrowski M, Burger J, Mielke T, Sprink T, Diebolder CA,
Guillen Schlippe YV, Spahn CMT |
(2024) "Transient
disome complex formation in native polysomes during
ongoing protein synthesis captured by cryo-EM."
Nat Commun, 15, 1756. doi:
10.1038/s41467-024-46092-3.
|
Escherichia coli paused disome complex (rotated disome
interface class 1) . SNAP output
|
|
8rct
|
ribosome |
cryo-EM (5.32 Å) |
Flugel T, Schacherl M, Unbehaun A, Schroeer B,
Dabrowski M, Burger J, Mielke T, Sprink T, Diebolder CA,
Guillen Schlippe YV, Spahn CMT |
(2024) "Transient
disome complex formation in native polysomes during
ongoing protein synthesis captured by cryo-EM."
Nat Commun, 15, 1756. doi:
10.1038/s41467-024-46092-3.
|
Escherichia coli paused disome complex (rotated disome
interface class 2) . SNAP output
|
|
8rd8
|
ribosome |
cryo-EM (2.62 Å) |
Helena-Bueno K, Rybak MY, Ekemezie CL, Sullivan R,
Brown CR, Dingwall C, Basle A, Schneider C, Connolly JPR,
Blaza JN, Csorgo B, Moynihan PJ, Gagnon MG, Hill CH,
Melnikov SV |
(2024) "A new
family of bacterial ribosome hibernation factors."
Nature, 626, 1125-1132. doi:
10.1038/s41586-024-07041-8.
|
cryo-EM structure of p. urativorans 70s ribosome in
complex with hibernation factors balon and raia
(structure 1). . SNAP
output
|
|
8rdv
|
ribosome |
cryo-EM (2.6 Å) |
Helena-Bueno K, Rybak MY, Ekemezie CL, Sullivan R,
Brown CR, Dingwall C, Basle A, Schneider C, Connolly JPR,
Blaza JN, Csorgo B, Moynihan PJ, Gagnon MG, Hill CH,
Melnikov SV |
(2024) "A new
family of bacterial ribosome hibernation factors."
Nature, 626, 1125-1132. doi:
10.1038/s41586-024-07041-8.
|
cryo-EM structure of p. urativorans 70s ribosome in
complex with hibernation factor balon, mrna and p-site
trna (structure 2). . SNAP output
|
|
8rdw
|
ribosome |
cryo-EM (2.74 Å) |
Helena-Bueno K, Rybak MY, Ekemezie CL, Sullivan R,
Brown CR, Dingwall C, Basle A, Schneider C, Connolly JPR,
Blaza JN, Csorgo B, Moynihan PJ, Gagnon MG, Hill CH,
Melnikov SV |
(2024) "A new
family of bacterial ribosome hibernation factors."
Nature, 626, 1125-1132. doi:
10.1038/s41586-024-07041-8.
|
cryo-EM structure of p. urativorans 70s ribosome in
complex with hibernation factor balon and ef-tu(gdp)
(structure 3). . SNAP
output
|
|
8rg0
|
ribosome |
cryo-EM (3.4 Å) |
Petrychenko V, Yi SH, Liedtke D, Peng BZ, Rodnina MV,
Fischer N |
(2025) "Structural
basis for translational control by the human 48S
initiation complex." Nat.Struct.Mol.Biol.,
32, 62-72. doi: 10.1038/s41594-024-01378-4.
|
Structure of human eif3 core from closed 48s
translation initiation complex . SNAP output
|
|
8rjb
|
ribosome |
cryo-EM (2.69 Å) |
Lewis AJO, Zhong F, Keenan RJ, Hegde RS |
(2024) "Structural
analysis of the dynamic ribosome-translocon
complex." Elife, 13. doi:
10.7554/eLife.95814.
|
Structure of the rabbit 80s ribosome stalled on a 2-tmd
rhodopsin intermediate in complex with sec61-ramp4 .
SNAP output
|
|
8rjc
|
ribosome |
cryo-EM (2.9 Å) |
Lewis AJO, Zhong F, Keenan RJ, Hegde RS |
(2024) "Structural
analysis of the dynamic ribosome-translocon
complex." Elife, 13. doi:
10.7554/eLife.95814.
|
Structure of the rabbit 80s ribosome stalled on a 2-tmd
rhodopsin intermediate in complex with sec61-trap, open
conformation 1 . SNAP
output
|
|
8rjd
|
ribosome |
cryo-EM (2.79 Å) |
Lewis AJO, Zhong F, Keenan RJ, Hegde RS |
(2024) "Structural
analysis of the dynamic ribosome-translocon
complex." Elife, 13. doi:
10.7554/eLife.95814.
|
Structure of the rabbit 80s ribosome stalled on a 2-tmd
rhodopsin intermediate in complex with sec61-trap, open
conformation 2 . SNAP
output
|
|
8rl2
|
ribosome |
cryo-EM (2.84 Å) |
Fiorentino F, Thoms M, Wild K, Denk T, Cheng J, Zeman
J, Sinning I, Hurt E, Beckmann R |
(2025) "Highly
conserved ribosome biogenesis pathways between human
and yeast revealed by the MDN1-NLE1 interaction and
NLE1 containing pre-60S subunits." Nucleic
Acids Res., 53. doi: 10.1093/nar/gkaf255.
|
Human pre-60s - state 5 . SNAP output
|
|
8rm5
|
splicing |
cryo-EM (6.9 Å) |
Zhang Z, Kumar V, Dybkov O, Will CL, Zhong J, Ludwig
SEJ, Urlaub H, Kastner B, Stark H, Luhrmann R |
(2024) "Structural
insights into the cross-exon to cross-intron
spliceosome switch." Nature,
630, 1012-1019. doi: 10.1038/s41586-024-07458-1.
|
cryo-EM structure of the cross-exon pre-b+5'sslng+atpys
complex . SNAP
output
|
|
8rn1
|
viral protein |
cryo-EM (3.64 Å) |
Arragain B, Krischuns T, Pelosse M, Drncova P,
Blackledge M, Naffakh N, Cusack S |
(2024) "Structures
of influenza A and B replication complexes give insight
into avian to human host adaptation and reveal a role
of ANP32 as an electrostatic chaperone for the
apo-polymerase." Nat Commun,
15, 6910. doi: 10.1038/s41467-024-51007-3.
|
Influenza b polymerase, monomeric encapsidase with 5'
crna hook bound . SNAP
output
|
|
8ro0
|
splicing |
cryo-EM (2.9 Å) |
Vorlander MK, Rothe P, Kleifeld J, Cormack ED, Veleti
L, Riabov-Bassat D, Fin L, Phillips AW, Cochella L,
Plaschka C |
(2024) "Mechanism
for the initiation of spliceosome disassembly."
Nature, 632, 443-450. doi:
10.1038/s41586-024-07741-1.
|
Structure of the c. elegans intron lariat spliceosome
primed for disassembly (ils') . SNAP output
|
|
8ro1
|
splicing |
cryo-EM (3.0 Å) |
Vorlander MK, Rothe P, Kleifeld J, Cormack ED, Veleti
L, Riabov-Bassat D, Fin L, Phillips AW, Cochella L,
Plaschka C |
(2024) "Mechanism
for the initiation of spliceosome disassembly."
Nature, 632, 443-450. doi:
10.1038/s41586-024-07741-1.
|
Structure of the c. elegans intron lariat spliceosome
double-primed for disassembly (ils'') . SNAP output
|
|
8ro2
|
splicing |
cryo-EM (3.5 Å) |
Vorlander MK, Rothe P, Kleifeld J, Cormack ED, Veleti
L, Riabov-Bassat D, Fin L, Phillips AW, Cochella L,
Plaschka C |
(2024) "Mechanism
for the initiation of spliceosome disassembly."
Nature, 632, 443-450. doi:
10.1038/s41586-024-07741-1.
|
Integrative structure of the human intron lariat
spliceosome (ils'') . SNAP output
|
|
8rpy
|
ribosome |
cryo-EM (2.64 Å) |
Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse
J, Gabrielli S, Grubmuller H, Bock LV, Krizsan A, Nikolay
R, Spahn CMT, Hoffmann R |
(2024) "Multimodal
binding and inhibition of bacterial ribosomes by the
antimicrobial peptides Api137 and Api88." Nat
Commun, 15, 3945. doi: 10.1038/s41467-024-48027-4.
|
Escherichia coli 50s subunit in complex with the
antimicrobial peptide api137 . SNAP output
|
|
8rpz
|
ribosome |
cryo-EM (2.44 Å) |
Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse
J, Gabrielli S, Grubmuller H, Bock LV, Krizsan A, Nikolay
R, Spahn CMT, Hoffmann R |
(2024) "Multimodal
binding and inhibition of bacterial ribosomes by the
antimicrobial peptides Api137 and Api88." Nat
Commun, 15, 3945. doi: 10.1038/s41467-024-48027-4.
|
Escherichia coli 50s subunit in complex with the
antimicrobial peptide api88 - conformation i . SNAP output
|
|
8rq0
|
ribosome |
cryo-EM (2.44 Å) |
Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse
J, Gabrielli S, Grubmuller H, Bock LV, Krizsan A, Nikolay
R, Spahn CMT, Hoffmann R |
(2024) "Multimodal
binding and inhibition of bacterial ribosomes by the
antimicrobial peptides Api137 and Api88." Nat
Commun, 15, 3945. doi: 10.1038/s41467-024-48027-4.
|
Escherichia coli 50s subunit in complex with the
antimicrobial peptide api88 - conformation ii .
SNAP output
|
|
8rq2
|
ribosome |
cryo-EM (2.44 Å) |
Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse
J, Gabrielli S, Grubmuller H, Bock LV, Krizsan A, Nikolay
R, Spahn CMT, Hoffmann R |
(2024) "Multimodal
binding and inhibition of bacterial ribosomes by the
antimicrobial peptides Api137 and Api88." Nat
Commun, 15, 3945. doi: 10.1038/s41467-024-48027-4.
|
Escherichia coli 50s subunit in complex with the
antimicrobial peptide api88 - conformation iii .
SNAP output
|
|
8rqk
|
transcription |
cryo-EM (2.65 Å) |
Grimm C, Bartuli J, Fischer U |
"Structure of the complete Vaccinia DNA-dependent RNA
polymerase complex at 2.65A resolution." |
Structure of the complete vaccinia DNA-dependent RNA
polymerase complex at 2.65a resolution . SNAP output
|
|
8rr1
|
RNA binding protein |
cryo-EM (2.93 Å) |
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K,
Bohnsack KE, Hillen HS |
(2025) "Molecular
basis of human nuclear and mitochondrial tRNA 3'
processing." Nat.Struct.Mol.Biol.,
32, 613-624. doi: 10.1038/s41594-024-01445-w.
|
Human mitochondrial rnase z complex with elac2-d550n
catalytic mutant and trna-tyr precursor (composite
model) . SNAP output
|
|
8rr3
|
RNA binding protein |
cryo-EM (3.4 Å) |
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K,
Bohnsack KE, Hillen HS |
(2025) "Molecular
basis of human nuclear and mitochondrial tRNA 3'
processing." Nat.Struct.Mol.Biol.,
32, 613-624. doi: 10.1038/s41594-024-01445-w.
|
Human mitochondrial rnase z complex with elac2-d550n
catalytic mutant and trna-gln precursor (composite
model) . SNAP output
|
|
8rr4
|
RNA binding protein |
cryo-EM (3.2 Å) |
Bhatta A, Kuhle B, Yu RD, Spanaus L, Ditter K,
Bohnsack KE, Hillen HS |
(2025) "Molecular
basis of human nuclear and mitochondrial tRNA 3'
processing." Nat.Struct.Mol.Biol.,
32, 613-624. doi: 10.1038/s41594-024-01445-w.
|
Human mitochondrial rnase z complex with elac2-d550n
catalytic mutant with ordered flexible arm and trna-tyr
precursor - (composite model) . SNAP output
|
|
8rri
|
ribosome |
cryo-EM (2.4 Å) |
Shao Q, Khawaja A, Nguyen MD, Singh V, Zhang J, Liu
Y, Nordin J, Adori M, Axel Innis C, Castro Dopico X,
Rorbach J |
(2025) "T cell
toxicity induced by tigecycline binding to the
mitochondrial ribosome." Nat Commun,
16, 4080. doi: 10.1038/s41467-025-59388-9.
|
Human mitochondrial ribosome in complex with antibiotic
tigecycline . SNAP
output
|
|
8rw1
|
ribosome |
cryo-EM (3.35 Å) |
Villamayor-Belinchon L, Sharma P, Gordiyenko Y,
Llacer JL, Hussain T |
(2024) "Structural
basis of AUC codon discrimination during translation
initiation in yeast." Nucleic Acids Res.,
52, 11317-11335. doi: 10.1093/nar/gkae737.
|
Structure of a yeast 48s-auc preinitiation complex in
closed conformation . SNAP output
|
|
8rwg
|
ribosome |
cryo-EM (2.46 Å) |
Mesa P, Jimenez-Fernandez A, La Rosa R,
Espinosa-Portero R, Johansen HK, Molin S, Montoya G |
"Detuning of the Ribosome Conformational Landscape
Promotes Antibiotic Resistance and Collateral
Sensitivity." |
Pao1 wild-type ribosome, r, reference map . SNAP output
|
|
8rxh
|
ribosome |
cryo-EM (2.93 Å) |
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H,
Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka
M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E,
Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF,
Yonath A, Michaeli S |
(2024) "Structural
and mechanistic insights into the function of
Leishmania ribosome lacking a single pseudouridine
modification." Cell Rep,
43, 114203. doi: 10.1016/j.celrep.2024.114203.
|
cryo-EM structure of leishmania major 80s ribosome with
a-p-e-site trna and mrna : parental strain . SNAP output
|
|
8rxx
|
ribosome |
cryo-EM (2.97 Å) |
Rajan KS, Aryal S, Hiregange DG, Bashan A, Madmoni H,
Olami M, Doniger T, Cohen-Chalamish S, Pescher P, Taoka
M, Nobe Y, Fedorenko A, Bose T, Zimermann E, Prina E,
Aharon-Hefetz N, Pilpel Y, Isobe T, Unger R, Spath GF,
Yonath A, Michaeli S |
(2024) "Structural
and mechanistic insights into the function of
Leishmania ribosome lacking a single pseudouridine
modification." Cell Rep,
43, 114203. doi: 10.1016/j.celrep.2024.114203.
|
cryo-EM structure of leishmania major 80s ribosome with
a-p-e-site trna and mrna : lm32cs3h1 sko strain .
SNAP output
|
|
8rza
|
hydrolase |
X-ray (2.1 Å) |
Vayssieres M, Juttner M, Haas K, Ancelin A,
Marchfelder A, Leulliot N, Ferreira-Cerca S, Blaud M |
(2024) "RNase W,
a conserved ribonuclease family with a novel active
site." Nucleic Acids Res.,
52, 13386-13401. doi: 10.1093/nar/gkae907.
|
Ribonuclease w . SNAP
output
|
|
8s1p
|
ribosome |
cryo-EM (1.96 Å) |
Takada H, Paternoga H, Fujiwara K, Nakamoto JA, Park
EN, Dimitrova-Paternoga L, Beckert B, Saarma M, Tenson T,
Buskirk AR, Atkinson GC, Chiba S, Wilson DN, Hauryliuk
V |
(2024) "A role
for the S4-domain containing protein YlmH in
ribosome-associated quality control in Bacillus
subtilis." Nucleic Acids Res.,
52, 8483-8499. doi: 10.1093/nar/gkae399.
|
Ylmh bound to ptrna-50s . SNAP output
|
|
8s1u
|
ribosome |
cryo-EM (3.4 Å) |
Takada H, Paternoga H, Fujiwara K, Nakamoto JA, Park
EN, Dimitrova-Paternoga L, Beckert B, Saarma M, Tenson T,
Buskirk AR, Atkinson GC, Chiba S, Wilson DN, Hauryliuk
V |
(2024) "A role
for the S4-domain containing protein YlmH in
ribosome-associated quality control in Bacillus
subtilis." Nucleic Acids Res.,
52, 8483-8499. doi: 10.1093/nar/gkae399.
|
Ylmh bound to stalled 50s subunits with rqch and ptrna
. SNAP output
|
|
8s8d
|
ribosome |
cryo-EM (3.45 Å) |
Villamayor-Belinchon L, Sharma P, Gordiyenko Y,
Llacer JL, Hussain T |
(2024) "Structural
basis of AUC codon discrimination during translation
initiation in yeast." Nucleic Acids Res.,
52, 11317-11335. doi: 10.1093/nar/gkae737.
|
Structure of a yeast 48s-auc preinitiation complex in
closed conformation (model py48s-auc-2) . SNAP output
|
|
8s8e
|
ribosome |
cryo-EM (3.85 Å) |
Villamayor-Belinchon L, Sharma P, Gordiyenko Y,
Llacer JL, Hussain T |
(2024) "Structural
basis of AUC codon discrimination during translation
initiation in yeast." Nucleic Acids Res.,
52, 11317-11335. doi: 10.1093/nar/gkae737.
|
Structure of a yeast 48s-auc preinitiation complex in
closed conformation (model py48s-auc-3.1) . SNAP output
|
|
8s8f
|
ribosome |
cryo-EM (3.95 Å) |
Villamayor-Belinchon L, Sharma P, Gordiyenko Y,
Llacer JL, Hussain T |
(2024) "Structural
basis of AUC codon discrimination during translation
initiation in yeast." Nucleic Acids Res.,
52, 11317-11335. doi: 10.1093/nar/gkae737.
|
Structure of a yeast 48s-auc preinitiation complex in
closed conformation (model py48s-auc-3.2) . SNAP output
|
|
8s8g
|
ribosome |
cryo-EM (4.0 Å) |
Villamayor-Belinchon L, Sharma P, Gordiyenko Y,
Llacer JL, Hussain T |
(2024) "Structural
basis of AUC codon discrimination during translation
initiation in yeast." Nucleic Acids Res.,
52, 11317-11335. doi: 10.1093/nar/gkae737.
|
Structure of a yeast 48s-auc preinitiation complex in
closed conformation (model py48s-auc-2.1) . SNAP output
|
|
8s8h
|
ribosome |
cryo-EM (4.0 Å) |
Villamayor-Belinchon L, Sharma P, Gordiyenko Y,
Llacer JL, Hussain T |
(2024) "Structural
basis of AUC codon discrimination during translation
initiation in yeast." Nucleic Acids Res.,
52, 11317-11335. doi: 10.1093/nar/gkae737.
|
Structure of a yeast 48s-auc preinitiation complex in
closed conformation (model py48s-auc-2.2) . SNAP output
|
|
8s8i
|
ribosome |
cryo-EM (4.3 Å) |
Villamayor-Belinchon L, Sharma P, Gordiyenko Y,
Llacer JL, Hussain T |
(2024) "Structural
basis of AUC codon discrimination during translation
initiation in yeast." Nucleic Acids Res.,
52, 11317-11335. doi: 10.1093/nar/gkae737.
|
Structure of a yeast 48s-auc preinitiation complex in
closed conformation (model py48s-auc-eif1) . SNAP output
|
|
8s8j
|
ribosome |
cryo-EM (4.7 Å) |
Villamayor-Belinchon L, Sharma P, Gordiyenko Y,
Llacer JL, Hussain T |
(2024) "Structural
basis of AUC codon discrimination during translation
initiation in yeast." Nucleic Acids Res.,
52, 11317-11335. doi: 10.1093/nar/gkae737.
|
Structure of a yeast 48s-auc preinitiation complex in
closed conformation (model py48s-auc-eif5) . SNAP output
|
|
8s8k
|
ribosome |
cryo-EM (4.0 Å) |
Villamayor-Belinchon L, Sharma P, Gordiyenko Y,
Llacer JL, Hussain T |
(2024) "Structural
basis of AUC codon discrimination during translation
initiation in yeast." Nucleic Acids Res.,
52, 11317-11335. doi: 10.1093/nar/gkae737.
|
Structure of a yeast 48s-auc preinitiation complex in
swivelled conformation (model py48s-auc-swiv-eif1) .
SNAP output
|
|
8s9t
|
RNA binding protein |
cryo-EM (2.52 Å) |
Schwartz EA, Bravo JPK, Ahsan M, Macias LA,
McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS,
Palermo G, Fineran PC, Fagerlund RD, Taylor DW |
(2024) "RNA
targeting and cleavage by the type III-Dv CRISPR
effector complex." Nat Commun,
15, 3324. doi: 10.1038/s41467-024-47506-y.
|
Crispr-cas type iii-d effector complex . SNAP output
|
|
8s9u
|
RNA binding protein-RNA |
cryo-EM (2.77 Å) |
Schwartz EA, Bravo JPK, Ahsan M, Macias LA,
McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS,
Palermo G, Fineran PC, Fagerlund RD, Taylor DW |
(2024) "RNA
targeting and cleavage by the type III-Dv CRISPR
effector complex." Nat Commun,
15, 3324. doi: 10.1038/s41467-024-47506-y.
|
Crispr-cas type iii-d effector complex bound to a
target RNA . SNAP
output
|
|
8s9v
|
RNA binding protein-RNA |
cryo-EM (3.0 Å) |
Schwartz EA, Bravo JPK, Ahsan M, Macias LA,
McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS,
Palermo G, Fineran PC, Fagerlund RD, Taylor DW |
(2024) "RNA
targeting and cleavage by the type III-Dv CRISPR
effector complex." Nat Commun,
15, 3324. doi: 10.1038/s41467-024-47506-y.
|
Crispr-cas type iii-d effector complex bound to a
self-target RNA in the pre-cleavage state . SNAP output
|
|
8s9x
|
RNA binding protein-RNA |
cryo-EM (3.44 Å) |
Schwartz EA, Bravo JPK, Ahsan M, Macias LA,
McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS,
Palermo G, Fineran PC, Fagerlund RD, Taylor DW |
(2024) "RNA
targeting and cleavage by the type III-Dv CRISPR
effector complex." Nat Commun,
15, 3324. doi: 10.1038/s41467-024-47506-y.
|
Crispr-cas type iii-d effector complex bound to
self-target RNA in a post-cleavage state . SNAP output
|
|
8scb
|
ribosome |
cryo-EM (2.5 Å) |
Coelho JPL, Yip MCJ, Oltion K, Taunton J, Shao S |
(2024) "The eRF1
degrader SRI-41315 acts as a molecular glue at the
ribosomal decoding center."
Nat.Chem.Biol., 20, 877-884.
doi: 10.1038/s41589-023-01521-0.
|
Terminating ribosome with sri-41315 . SNAP output
|
|
8scz
|
immune system |
cryo-EM (3.4 Å) |
Wang W, Pyle AM |
"Cryo-EM structure of 14aa-GS RIG-I in complex with
p3SLR30." |
cryo-EM structure of 14aa-gs rig-i in complex with
p3slr30 . SNAP
output
|
|
8sd0
|
immune system |
cryo-EM (3.8 Å) |
Wang W, Pyle AM |
"Cryo-EM structure of RIG-I in complex with
p3SLR14." |
cryo-EM structure of rig-i in complex with p3slr14 .
SNAP output
|
|
8sh5
|
RNA-immune system |
X-ray (2.75 Å) |
Lewicka A, Roman C, Jones S, Disare M, Rice PA,
Piccirilli JA |
(2023) "Crystal
structure of a cap-independent translation enhancer
RNA." Nucleic Acids Res.,
51, 8891-8907. doi: 10.1093/nar/gkad649.
|
Crystal structure of 3'cap-independent translation
enhancers (cite) from pea enation mosaic virus RNA 2
(pemv2) with fab bl3-6k170a . SNAP output
|
|
8sj7
|
RNA binding protein-RNA |
X-ray (2.09 Å) |
Qiu C, Zhang Z, Wine RN, Campbell ZT, Zhang J, Hall
TMT |
(2023) "Intra-
and inter-molecular regulation by
intrinsically-disordered regions governs PUF protein
RNA binding." Nat Commun,
14, 7323. doi: 10.1038/s41467-023-43098-1.
|
Crystal structure of fbf-2 (rbd+ct) in complex with
compact fbe RNA . SNAP
output
|
|
8snx
|
viral protein-RNA |
cryo-EM (3.4 Å) |
Cao D, Gao Y, Chen Z, Gooneratne I, Roesler C, Mera
C, D'Cunha P, Antonova A, Katta D, Romanelli S, Wang Q,
Rice S, Lemons W, Ramanathan A, Liang B |
(2024) "Structures
of the promoter-bound respiratory syncytial virus
polymerase." Nature, 625,
611-617. doi: 10.1038/s41586-023-06867-y.
|
cryo-EM structure of the respiratory syncytial virus
polymerase (l:p) bound to the leader promoter .
SNAP output
|
|
8sny
|
viral protein-RNA |
cryo-EM (3.41 Å) |
Cao D, Gao Y, Chen Z, Gooneratne I, Roesler C, Mera
C, D'Cunha P, Antonova A, Katta D, Romanelli S, Wang Q,
Rice S, Lemons W, Ramanathan A, Liang B |
(2024) "Structures
of the promoter-bound respiratory syncytial virus
polymerase." Nature, 625,
611-617. doi: 10.1038/s41586-023-06867-y.
|
cryo-EM structure of the respiratory syncytial virus
polymerase (l:p) bound to the trailer complementary
promoter . SNAP
output
|
|
8sq9
|
viral protein |
cryo-EM (2.9 Å) |
Small GI, Fedorova O, Olinares PDB, Chandanani J,
Banerjee A, Choi YJ, Molina H, Chait BT, Darst SA,
Campbell EA |
(2023) "Structural
and functional insights into the enzymatic plasticity
of the SARS-CoV-2 NiRAN domain." Mol.Cell,
83, 3921-3930.e7. doi: 10.1016/j.molcel.2023.10.001.
|
Sars-cov-2 replication-transcription complex bound to
nsp9 and umpcpp, as a pre-catalytic nmpylation
intermediate . SNAP
output
|
|
8sqj
|
viral protein |
cryo-EM (3.06 Å) |
Small GI, Fedorova O, Olinares PDB, Chandanani J,
Banerjee A, Choi YJ, Molina H, Chait BT, Darst SA,
Campbell EA |
(2023) "Structural
and functional insights into the enzymatic plasticity
of the SARS-CoV-2 NiRAN domain." Mol.Cell,
83, 3921-3930.e7. doi: 10.1016/j.molcel.2023.10.001.
|
Sars-cov-2 replication-transcription complex bound to
RNA-nsp9, as a noncatalytic RNA-nsp9 binding mode .
SNAP output
|
|
8sqk
|
viral protein |
cryo-EM (3.01 Å) |
Small GI, Fedorova O, Olinares PDB, Chandanani J,
Banerjee A, Choi YJ, Molina H, Chait BT, Darst SA,
Campbell EA |
(2023) "Structural
and functional insights into the enzymatic plasticity
of the SARS-CoV-2 NiRAN domain." Mol.Cell,
83, 3921-3930.e7. doi: 10.1016/j.molcel.2023.10.001.
|
Sars-cov-2 replication-transcription complex bound to
RNA-nsp9 and gdp-betas, as a pre-catalytic
dernaylation-mrna capping intermediate . SNAP output
|
|
8ssw
|
RNA binding protein-RNA |
X-ray (2.4 Å) |
Song H, Ji X |
"Crystal structure of DEAD-box RNA helicase DDX3X in
complex with ADP at pre-unwound state." |
Crystal structure of dead-box RNA helicase ddx3x in
complex with adp at pre-unwound state . SNAP output
|
|
8sxu
|
RNA binding protein-RNA |
cryo-EM (3.66 Å) |
Baldwin ET, van Eeuwen T, Hoyos D, Zalevsky A,
Tchesnokov EP, Sanchez R, Miller BD, Di Stefano LH, Ruiz
FX, Hancock M, Isik E, Mendez-Dorantes C, Walpole T,
Nichols C, Wan P, Riento K, Halls-Kass R, Augustin M,
Lammens A, Jestel A, Upla P, Xibinaku K, Congreve S,
Hennink M, Rogala KB, Schneider AM, Fairman JE,
Christensen SM, Desrosiers B, Bisacchi GS, Saunders OL,
Hafeez N, Miao W, Kapeller R, Zaller DM, Sali A,
Weichenrieder O, Burns KH, Gotte M, Rout MP, Arnold E,
Greenbaum BD, Romero DL, LaCava J, Taylor MS |
(2024) "Structures,
functions and adaptations of the human LINE-1 ORF2
protein." Nature, 626,
194-206. doi: 10.1038/s41586-023-06947-z.
|
Structure of line-1 orf2p with an oligo(a) template .
SNAP output
|
|
8syl
|
ribosome |
cryo-EM (2.9 Å) |
Seely SM, Parajuli NP, De Tarafder A, Ge X, Sanyal S,
Gagnon MG |
(2023) "Molecular
basis of the pleiotropic effects by the antibiotic
amikacin on the ribosome." Nat Commun,
14, 4666. doi: 10.1038/s41467-023-40416-5.
|
cryo-EM structure of the escherichia coli 70s ribosome
in complex with amikacin, mrna, and a-, p-, and e-site
trnas . SNAP output
|
|
8t29
|
RNA-immune system |
X-ray (3.13 Å) |
Ojha M, Vogt J, Das NK, Redmond E, Singh K, Banna HA,
Sadat T, Koirala D |
(2024) "Structure
of saguaro cactus virus 3' translational enhancer
mimics 5' cap for eIF4E binding."
Proc.Natl.Acad.Sci.USA, 121,
e2313677121. doi: 10.1073/pnas.2313677121.
|
Crystal structure of scv pte RNA in complex with fab
bl3-6 . SNAP output
|
|
8t2a
|
RNA-immune system |
X-ray (3.17 Å) |
Ojha M, Vogt J, Das NK, Redmond E, Singh K, Banna HA,
Sadat T, Koirala D |
(2024) "Structure
of saguaro cactus virus 3' translational enhancer
mimics 5' cap for eIF4E binding."
Proc.Natl.Acad.Sci.USA, 121,
e2313677121. doi: 10.1073/pnas.2313677121.
|
Crystal structure of scv pte g18a mutant RNA in complex
with fab bl3-6 . SNAP
output
|
|
8t2b
|
RNA-immune system |
X-ray (3.18 Å) |
Ojha M, Vogt J, Das NK, Redmond E, Singh K, Banna HA,
Sadat T, Koirala D |
(2024) "Structure
of saguaro cactus virus 3' translational enhancer
mimics 5' cap for eIF4E binding."
Proc.Natl.Acad.Sci.USA, 121,
e2313677121. doi: 10.1073/pnas.2313677121.
|
Crystal structure of scv pte g18c mutant RNA in complex
with fab bl3-6 . SNAP
output
|
|
8t2o
|
RNA-immune system |
X-ray (3.29 Å) |
Ojha M, Vogt J, Das NK, Redmond E, Singh K, Banna HA,
Sadat T, Koirala D |
(2024) "Structure
of saguaro cactus virus 3' translational enhancer
mimics 5' cap for eIF4E binding."
Proc.Natl.Acad.Sci.USA, 121,
e2313677121. doi: 10.1073/pnas.2313677121.
|
Crystal structure of scv pte g18u RNA in complex with
fab bl3-6 . SNAP
output
|
|
8t2r
|
transferase-RNA |
cryo-EM (3.1 Å) |
Xu L, Liu T, Chung K, Pyle AM |
(2023) "Structural
insights into intron catalysis and dynamics during
splicing." Nature, 624,
682-688. doi: 10.1038/s41586-023-06746-6.
|
Structure of a group ii intron ribonucleoprotein in the
pre-ligation (pre-2f) state . SNAP output
|
|
8t2s
|
transferase-RNA |
cryo-EM (3.0 Å) |
Xu L, Liu T, Chung K, Pyle AM |
(2023) "Structural
insights into intron catalysis and dynamics during
splicing." Nature, 624,
682-688. doi: 10.1038/s41586-023-06746-6.
|
Structure of a group ii intron ribonucleoprotein in the
pre-branching (pre-1f) state . SNAP output
|
|
8t2t
|
transferase-RNA |
cryo-EM (3.0 Å) |
Xu L, Liu T, Chung K, Pyle AM |
(2023) "Structural
insights into intron catalysis and dynamics during
splicing." Nature, 624,
682-688. doi: 10.1038/s41586-023-06746-6.
|
Structure of a group ii intron ribonucleoprotein in the
post-ligation (post-2f) state . SNAP output
|
|
8t2x
|
ribosome |
cryo-EM (2.46 Å) |
Zhao Y, Li H |
"Regulation of Translation by Ribosome RNA
2'-Hydroxyl Methylation." |
Hypomethylated yeast 80s bound with cycloheximide,
p-site trna, a-site trna, messenger RNA and eif5a, pre
. SNAP output
|
|
8t2y
|
ribosome |
cryo-EM (2.2 Å) |
Zhao Y, Li H |
"Regulation of Translation by Ribosome RNA
2'-O-Methylation." |
Hypomethylated yeast 80s bound with cycloheximide,
p-site trna, and a-site trna, messenger RNA, pre .
SNAP output
|
|
8t2z
|
ribosome |
cryo-EM (2.4 Å) |
Zhao Y, Rai Y, Li H |
"Structures of Hypopseudouridylated Ribosome in
IRES-mediated Translation." |
Hypomethylated yeast 80s bound with cycloheximide,
p-site trna, and a-site trna, messenger RNA, post .
SNAP output
|
|
8t30
|
ribosome |
cryo-EM (2.88 Å) |
Zhao Y, Li H |
"Regulation of Translation by Ribosome RNA
2'-O-Methylation." |
Hypomethylated yeast 80s bound with cycloheximide,
unmodified u2921, mid rotated . SNAP output
|
|
8t3a
|
ribosome |
cryo-EM (2.86 Å) |
Zhao Y, Li H |
"Regulation of Translation by Ribosome RNA
2'-O-Methylation." |
Hypomethylated yeast 80s bound with taura syndrome
virus (tsv) internal ribosome entry site (ires), eef2,
gdp, sordarin, and hibernating factor los2 . SNAP output
|
|
8t4s
|
ribosome-viral protein |
cryo-EM (2.6 Å) |
Devarkar SC, Vetick M, Balaji S, Lomakin IB, Yang L,
Jin D, Gilbert WV, Chen S, Xiong Y |
(2023) "Structural
basis for translation inhibition by MERS-CoV Nsp1
reveals a conserved mechanism for
betacoronaviruses." Cell Rep,
42, 113156. doi: 10.1016/j.celrep.2023.113156.
|
Mers-cov nsp1 protein bound to the human 40s ribosomal
subunit . SNAP
output
|
|
8t5d
|
ribosome |
cryo-EM (3.2 Å) |
Acosta-Reyes FJ, Bhattacharjee S, Gottesman M, Frank
J |
(2024) "How
Dedicated Ribosomes Translate a Leaderless mRNA."
J.Mol.Biol., 436, 168423.
doi: 10.1016/j.jmb.2023.168423.
|
cryo-EM studies of the interplay between us2 ribosomal
protein and leaderless mrna during bacterial
translation initiation . SNAP output
|
|
8t5h
|
ribosome |
cryo-EM (3.3 Å) |
Acosta-Reyes FJ, Bhattacharjee S, Gottesman M, Frank
J |
(2024) "How
Dedicated Ribosomes Translate a Leaderless mRNA."
J.Mol.Biol., 436, 168423.
doi: 10.1016/j.jmb.2023.168423.
|
cryo-EM studies of the interplay between us2 ribosomal
protein and leaderless mrna during bacterial
translation initiation . SNAP output
|
|
8t5s
|
antiviral protein-RNA |
cryo-EM (2.9 Å) |
Consalvo CD, Aderounmu AM, Donelick HM, Aruscavage
PJ, Eckert DM, Shen PS, Bass BL |
(2024) "Caenorhabditis
elegans Dicer acts with the RIG-I-like helicase DRH-1
and RDE-4 to cleave dsRNA." Elife,
13. doi: 10.7554/eLife.93979.
|
cryo-EM structure of drh-1 helicase and c-terminal
domain bound to dsrna . SNAP output
|
|
8t65
|
antiviral protein-RNA |
X-ray (2.09 Å) |
Baca CF, Yu Y, Rostol JT, Majumder P, Patel DJ,
Marraffini LA |
(2024) "The
CRISPR effector Cam1 mediates membrane depolarization
for phage defence." Nature,
625, 797-804. doi: 10.1038/s41586-023-06902-y.
|
Ca4 bound cam1 . SNAP
output
|
|
8t66
|
immune system-RNA |
X-ray (1.85 Å) |
Baca CF, Yu Y, Rostol JT, Majumder P, Patel DJ,
Marraffini LA |
(2024) "The
CRISPR effector Cam1 mediates membrane depolarization
for phage defence." Nature,
625, 797-804. doi: 10.1038/s41586-023-06902-y.
|
Ca6 bound cam1 . SNAP
output
|
|
8t8b
|
ribosome-RNA |
X-ray (2.65 Å) |
Thaler J, Syroegin EA, Breuker K, Polikanov YS,
Micura R |
(2023) "Practical
Synthesis of N -Formylmethionylated Peptidyl-tRNA
Mimics." Acs Chem.Biol.,
18, 2233-2239. doi: 10.1021/acschembio.3c00237.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, a-site
aminoacyl-trna analog acc-pmn, and p-site
formyl-mai-tripeptidyl-trna analog acca-iamf at 2.65a
resolution . SNAP
output
|
|
8t8c
|
ribosome |
X-ray (2.6 Å) |
Thaler J, Syroegin EA, Breuker K, Polikanov YS,
Micura R |
(2023) "Practical
Synthesis of N -Formylmethionylated Peptidyl-tRNA
Mimics." Acs Chem.Biol.,
18, 2233-2239. doi: 10.1021/acschembio.3c00237.
|
Crystal structure of the thermus thermophilus 70s
ribosome in complex with protein y, a-site
aminoacyl-trna analog acc-pmn, and p-site
formyl-mfi-tripeptidyl-trna analog acca-ifmf at 2.60a
resolution . SNAP
output
|
|
8tdv
|
hydrolase |
cryo-EM (3.44 Å) |
Orris B, Sung MW, Bhat S, Xu Y, Huynh KW, Han S,
Johnson DC, Bosbach B, Shields DJ, Stivers JT |
(2023) "Guanine-containing
ssDNA and RNA induce dimeric and tetrameric structural
forms of SAMHD1." Nucleic Acids Res.,
51, 12443-12458. doi: 10.1093/nar/gkad971.
|
Ssrna bound samhd1 t closed . SNAP output
|
|
8tdw
|
hydrolase |
cryo-EM (3.04 Å) |
Orris B, Sung MW, Bhat S, Xu Y, Huynh KW, Han S,
Johnson DC, Bosbach B, Shields DJ, Stivers JT |
(2023) "Guanine-containing
ssDNA and RNA induce dimeric and tetrameric structural
forms of SAMHD1." Nucleic Acids Res.,
51, 12443-12458. doi: 10.1093/nar/gkad971.
|
Ssrna bound samhd1 t open . SNAP output
|
|
8thq
|
RNA binding protein-RNA |
X-ray (2.41 Å) |
Aluri KC, Datta D, Waldron S, Taneja N, Qin J,
Donnelly DP, Theile CS, Guenther DC, Lei L, Harp JM,
Pallan PS, Egli M, Zlatev I, Manoharan M |
(2024) "Single-Stranded
Hairpin Loop RNAs (loopmeRNAs) Potently Induce Gene
Silencing through the RNA Interference Pathway."
J.Am.Chem.Soc. doi: 10.1021/jacs.4c07902.
|
Nonamer RNA bound to hago2-paz . SNAP output
|
|
8tl0
|
immune system |
cryo-EM (3.1 Å) |
Steens JA, Bravo JPK, Salazar CRP, Yildiz C, Amieiro
AM, Kostlbacher S, Prinsen SHP, Andres AS, Patinios C,
Bardis A, Barendregt A, Scheltema RA, Ettema TJG, van der
Oost J, Taylor DW, Staals RHJ |
(2024) "Type
III-B CRISPR-Cas cascade of proteolytic cleavages."
Science, 383, 512-519. doi:
10.1126/science.adk0378.
|
Structure of activated saved-chat filament . SNAP output
|
|
8toc
|
virus-RNA |
cryo-EM (3.11 Å) |
Meng R, Xing Z, Chang JY, Yu Z, Thongchol J, Xiao W,
Wang Y, Chamakura K, Zeng Z, Wang F, Young R, Zeng L,
Zhang J |
(2024) "Structural
basis of Acinetobacter type IV pili targeting by an RNA
virus." Nat Commun, 15,
2746. doi: 10.1038/s41467-024-47119-5.
|
Acinetobacter phage ap205 . SNAP output
|
|
8tpu
|
ribosome |
cryo-EM (4.1 Å) |
Anton L, Cheng W, Haile M, Cobb DW, Zhu X, Han L, Li
E, Nair A, Lee CL, Ho CM |
"Divergent translational landscape reflects
adaptation to biased codon usage in malaria
parasites." |
Subtomogram averaged consensus structure of the
malarial 80s ribosome in plasmodium falciparum-infected
human erythrocytes . SNAP output
|
|
8tux
|
viral protein |
cryo-EM (3.9 Å) |
Thongchol J, Yu Z, Harb L, Lin Y, Koch M, Theodore M,
Narsaria U, Shaevitz J, Gitai Z, Wu Y, Zhang J, Zeng
L |
(2024) "Removal
of Pseudomonas type IV pili by a small RNA virus."
Science, 384, eadl0635. doi:
10.1126/science.adl0635.
|
Capsid of mature pp7 virion with 3'end region of pp7
genomic RNA . SNAP
output
|
|
8uau
|
transferase-RNA |
cryo-EM (5.7 Å) |
Lan X, Huang W, Kim SB, Fu D, Abeywansha T, Lou J,
Balamurugan U, Kwon YT, Ji CH, Taylor DJ, Zhang Y |
(2024) "Oligomerization
and a distinct tRNA-binding loop are important
regulators of human arginyl-transferase function."
Nat Commun, 15, 6350. doi:
10.1038/s41467-024-50719-w.
|
Human ate1 in complex with arg-trna and a peptide
substrate . SNAP
output
|
|
8ub7
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG,
Ghosh P |
(2025) "RNA
control of reverse transcription in a
diversity-generating retroelement."
Nature, 638, 1122-1129. doi:
10.1038/s41586-024-08405-w.
|
Diversity-generating retroelement (dgr)
ribonucleoprotein reverse transcriptase - active state
(n-occupied) . SNAP
output
|
|
8ub8
|
RNA binding protein-RNA |
cryo-EM (3.28 Å) |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG,
Ghosh P |
(2025) "RNA
control of reverse transcription in a
diversity-generating retroelement."
Nature, 638, 1122-1129. doi:
10.1038/s41586-024-08405-w.
|
Diversity-generating retroelement (dgr)
ribonucleoprotein reverse transcriptase - pre-active
state 1a . SNAP
output
|
|
8ub9
|
RNA binding protein-RNA |
cryo-EM (3.07 Å) |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG,
Ghosh P |
(2025) "RNA
control of reverse transcription in a
diversity-generating retroelement."
Nature, 638, 1122-1129. doi:
10.1038/s41586-024-08405-w.
|
Diversity-generating retroelement (dgr)
ribonucleoprotein reverse transcriptase- active state
(n-empty) 1a . SNAP
output
|
|
8uba
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG,
Ghosh P |
(2025) "RNA
control of reverse transcription in a
diversity-generating retroelement."
Nature, 638, 1122-1129. doi:
10.1038/s41586-024-08405-w.
|
Diversity-generating retroelement (dgr)
ribonucleoprotein reverse transcriptase - pre-active
state 1b . SNAP
output
|
|
8ubb
|
RNA binding protein-RNA |
cryo-EM (3.23 Å) |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG,
Ghosh P |
(2025) "RNA
control of reverse transcription in a
diversity-generating retroelement."
Nature, 638, 1122-1129. doi:
10.1038/s41586-024-08405-w.
|
Diversity-generating retroelement (dgr)
ribonucleoprotein reverse transcriptase - active state
(n-empty) 1b . SNAP
output
|
|
8ubc
|
RNA binding protein-RNA |
cryo-EM (3.29 Å) |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG,
Ghosh P |
(2025) "RNA
control of reverse transcription in a
diversity-generating retroelement."
Nature, 638, 1122-1129. doi:
10.1038/s41586-024-08405-w.
|
Diversity-generating retroelement (dgr)
ribonucleoprotein reverse transcriptase - resting state
1b . SNAP output
|
|
8ubd
|
RNA binding protein-RNA |
cryo-EM (3.05 Å) |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG,
Ghosh P |
(2025) "RNA
control of reverse transcription in a
diversity-generating retroelement."
Nature, 638, 1122-1129. doi:
10.1038/s41586-024-08405-w.
|
Diversity-generating retroelement (dgr)
ribonucleoprotein reverse transcriptase - pre-active
state 2 . SNAP
output
|
|
8ube
|
RNA binding protein-RNA |
cryo-EM (3.05 Å) |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG,
Ghosh P |
(2025) "RNA
control of reverse transcription in a
diversity-generating retroelement."
Nature, 638, 1122-1129. doi:
10.1038/s41586-024-08405-w.
|
Diversity-generating retroelement (dgr)
ribonucleoprotein reverse transcriptase - resting state
1a . SNAP output
|
|
8ubf
|
RNA binding protein-RNA |
cryo-EM (3.61 Å) |
Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG,
Ghosh P |
(2025) "RNA
control of reverse transcription in a
diversity-generating retroelement."
Nature, 638, 1122-1129. doi:
10.1038/s41586-024-08405-w.
|
Diversity-generating retroelement (dgr)
ribonucleoprotein - resting state 1c . SNAP output
|
|
8ud3
|
viral protein-RNA |
cryo-EM (2.67 Å) |
Ito F, Yang H, Zhou ZH, Chen XS |
(2024) "Structural
basis for polyuridine tract recognition by SARS-CoV-2
Nsp15." Protein Cell, 15,
547-552. doi: 10.1093/procel/pwae009.
|
Sars-cov-2 nsp15 bound to poly(a-u) RNA, consensus form
. SNAP output
|
|
8ud4
|
viral protein-RNA |
cryo-EM (3.25 Å) |
Ito F, Yang H, Zhou ZH, Chen XS |
(2024) "Structural
basis for polyuridine tract recognition by SARS-CoV-2
Nsp15." Protein Cell, 15,
547-552. doi: 10.1093/procel/pwae009.
|
Sars-cov-2 nsp15 bound to poly(a-u) RNA, state 1 .
SNAP output
|
|
8ud5
|
viral protein-RNA |
cryo-EM (3.13 Å) |
Ito F, Yang H, Zhou ZH, Chen XS |
(2024) "Structural
basis for polyuridine tract recognition by SARS-CoV-2
Nsp15." Protein Cell, 15,
547-552. doi: 10.1093/procel/pwae009.
|
Sars-cov-2 nsp15 bound to poly(a-u) RNA, state 2 .
SNAP output
|
|
8ud6
|
ribosome-RNA |
X-ray (2.7 Å) |
Wu KJY, Tresco BIC, Ramkissoon A, Aleksandrova EV,
Syroegin EA, See DNY, Liow P, Dittemore GA, Yu M,
Testolin G, Mitcheltree MJ, Liu RY, Svetlov MS, Polikanov
YS, Myers AG |
(2024) "An
antibiotic preorganized for ribosomal binding overcomes
antimicrobial resistance." Science,
383, 721-726. doi: 10.1126/science.adk8013.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with cresomycin, mrna,
deacylated a-site trnaphe, aminoacylated p-site
fmet-trnamet, and deacylated e-site trnaphe at 2.70a
resolution . SNAP
output
|
|
8ud7
|
ribosome-RNA |
X-ray (2.55 Å) |
Wu KJY, Tresco BIC, Ramkissoon A, Aleksandrova EV,
Syroegin EA, See DNY, Liow P, Dittemore GA, Yu M,
Testolin G, Mitcheltree MJ, Liu RY, Svetlov MS, Polikanov
YS, Myers AG |
(2024) "An
antibiotic preorganized for ribosomal binding overcomes
antimicrobial resistance." Science,
383, 721-726. doi: 10.1126/science.adk8013.
|
Crystal structure of the a2058-n6-dimethylated thermus
thermophilus 70s ribosome in complex with cresomycin,
mrna, deacylated a-site trnaphe, aminoacylated p-site
fmet-trnamet, and deacylated e-site trnaphe at 2.70a
resolution . SNAP
output
|
|
8ud8
|
ribosome-RNA |
X-ray (2.6 Å) |
Wu KJY, Tresco BIC, Ramkissoon A, Aleksandrova EV,
Syroegin EA, See DNY, Liow P, Dittemore GA, Yu M,
Testolin G, Mitcheltree MJ, Liu RY, Svetlov MS, Polikanov
YS, Myers AG |
(2024) "An
antibiotic preorganized for ribosomal binding overcomes
antimicrobial resistance." Science,
383, 721-726. doi: 10.1126/science.adk8013.
|
Crystal structure of the a2503-c2,c8-dimethylated
thermus thermophilus 70s ribosome in complex with
cresomycin, mrna, deacylated a-site trnaphe,
aminoacylated p-site fmet-trnamet, and deacylated
e-site trnaphe at 2.70a resolution . SNAP output
|
|
8uiw
|
RNA |
X-ray (2.77 Å) |
Krochmal D, Roman C, Lewicka A, Shao Y, Piccirilli
JA |
(2024) "Structural
basis for promiscuity in ligand recognition by yjdF
riboswitch." Cell Discov,
10, 37. doi: 10.1038/s41421-024-00663-2.
|
Yjdf riboswitch from r. gauvreauii in complex with
chelerythrine bound to fab bl3-6 s97n . SNAP output
|
|
8ujc
|
ribosome |
cryo-EM (2.87 Å) |
Wei Z, Yong X |
"In situ human 60S ribosome." |
In situ human 60s ribosome . SNAP output
|
|
8ujd
|
ribosome |
cryo-EM (2.96 Å) |
Wei Z, Yong X |
"In situ human 60S ribosome with eIF6." |
In situ human 60s ribosome with eif6 . SNAP output
|
|
8up5
|
RNA binding protein |
cryo-EM (3.56 Å) |
Ona Chuquimarca SM, Beenstock J, Daou S, Porat J,
Keszei AFA, Yin JZ, Beschauner T, Bayfield MA,
Mazhab-Jafari MT, Sicheri F |
(2024) "Structures
of KEOPS bound to tRNA reveal functional roles of the
kinase Bud32." Nat Commun,
15, 10633. doi: 10.1038/s41467-024-54787-w.
|
Structure of the keops complex (cgi121-bud32-kae1-pcc1)
bound to trna in its native-like conformation. .
SNAP output
|
|
8urb
|
replication, transferase-RNA |
cryo-EM (3.4 Å) |
Anderson TK, Hoferle PJ, Lee KW, Coon JJ,
Kirchdoerfer RN |
(2023) "An
alphacoronavirus polymerase structure reveals conserved
co-factor functions." Biorxiv. doi:
10.1101/2023.03.15.532841.
|
Porcine epidemic diarrhea virus complete core
polymerase complex . SNAP output
|
|
8urj
|
RNA binding protein-RNA |
cryo-EM (4.25 Å) |
Smith AM, Cheng Y, Frankel AD, Li Y, Velarde A |
"Structure of the HIV-1 RNA Nuclear Export Complex
Reveals Crm1 Versatility." |
cryo-EM structure of the hiv-1 nuclear export complex .
SNAP output
|
|
8urm
|
ribosome |
cryo-EM (3.0 Å) |
Kimbrough EM, Nguyen HA, Li H, Bailey NA, Ning W,
Mattingly JM, Gamper H, Hou YM, Gonzalez RL, Dunham
CM |
(2025) "An RNA modification prevents extended
codon-anticodon interactions from facilitating +1
frameshifting." Nat Commun. |
E. coli 70s ribosome with unmodified trnapro(ggg) bound
to slippery p-site ccc-c codon and trnaval(uac) in the
a site . SNAP output
|
|
8usn
|
viral protein |
cryo-EM (8.9 Å) |
Watanabe R, Zyla D, Parekh D, Hong C, Jones Y,
Schendel SL, Wan W, Castillon G, Saphire EO |
(2024) "Intracellular
Ebola virus nucleocapsid assembly revealed by in situ
cryo-electron tomography." Cell,
187, 5587-5603.e19. doi: 10.1016/j.cell.2024.08.044.
|
Intracellular cryo-tomography structure of ebov
nucleocapsid at 8.9 angstrom . SNAP output
|
|
8ust
|
viral protein-RNA |
cryo-EM (7.3 Å) |
Watanabe R, Zyla D, Parekh D, Hong C, Jones Y,
Schendel SL, Wan W, Castillon G, Saphire EO |
(2024) "Intracellular
Ebola virus nucleocapsid assembly revealed by in situ
cryo-electron tomography." Cell,
187, 5587-5603.e19. doi: 10.1016/j.cell.2024.08.044.
|
In-virion structure of ebola virus nucleocapsid-like
assemblies from recombinant virus-like particles
(nucleoprotein, vp24,vp35,vp40) . SNAP output
|
|
8ut0
|
ribosome |
cryo-EM (3.22 Å) |
Musalgaonkar S, Yelland JN, Chitale R, Rao S, Ozadam
H, Taylor DW, Cenik C, Johnson AW |
(2025) "The
assembly factor Reh1 is released from the ribosome
during its initial round of translation." Nat
Commun, 16, 1278. doi: 10.1038/s41467-025-55844-8.
|
Eukaryotic 80s ribosome with reh1, eif5a and a-p site
trna . SNAP output
|
|
8uta
|
RNA |
X-ray (3.05 Å) |
Krochmal D, Roman C, Lewicka A, Shao Y, Piccirilli
JA |
(2024) "Structural
basis for promiscuity in ligand recognition by yjdF
riboswitch." Cell Discov,
10, 37. doi: 10.1038/s41421-024-00663-2.
|
Yjdf riboswitch from r. gauvreauii in complex with
proflavine bound to fab bl3-6 s97n . SNAP output
|
|
8uti
|
ribosome |
cryo-EM (3.13 Å) |
Musalgaonkar S, Yelland JN, Chitale R, Rao S, Ozadam
H, Taylor DW, Cenik C, Johnson AW |
(2025) "The
assembly factor Reh1 is released from the ribosome
during its initial round of translation." Nat
Commun, 16, 1278. doi: 10.1038/s41467-025-55844-8.
|
Eukaryotic 80s ribosome with reh1 and a-p site trna .
SNAP output
|
|
8utj
|
ribosome |
cryo-EM (3.5 Å) |
Kimbrough EM, Nguyen HA, Li H, Bailey NA, Ning W,
Mattingly JM, Gamper H, Hou YM, Gonzalez RL, Dunham
CM |
(2025) "An RNA modification prevents extended
codon-anticodon interactions from facilitating +1
frameshifting." Nat Commun. |
E. coli 70s ribosome with unmodified lys-trnapro(ggg)
bound to slippery p-site ccc-c codon in the 0 frame .
SNAP output
|
|
8uu4
|
ribosome |
cryo-EM (3.0 Å) |
Seely SM, Basu RS, Gagnon MG |
(2024) "Mechanistic
insights into the alternative ribosome recycling by
HflXr." Nucleic Acids Res.,
52, 4053-4066. doi: 10.1093/nar/gkae128.
|
cryo-EM structure of the listeria innocua 70s ribosome
in complex with hpf (structure i-a) . SNAP output
|
|
8uu5
|
ribosome |
cryo-EM (3.0 Å) |
Seely SM, Basu RS, Gagnon MG |
(2024) "Mechanistic
insights into the alternative ribosome recycling by
HflXr." Nucleic Acids Res.,
52, 4053-4066. doi: 10.1093/nar/gkae128.
|
cryo-EM structure of the listeria innocua 70s ribosome
(head-swiveled) in complex with pe-e-trna (structure
i-b) . SNAP output
|
|
8uu6
|
ribosome |
cryo-EM (3.3 Å) |
Seely SM, Basu RS, Gagnon MG |
(2024) "Mechanistic
insights into the alternative ribosome recycling by
HflXr." Nucleic Acids Res.,
52, 4053-4066. doi: 10.1093/nar/gkae128.
|
cryo-EM structure of the ratcheted listeria innocua 70s
ribosome in complex with p-e-trna (structure ii-a) .
SNAP output
|
|
8uu7
|
ribosome |
cryo-EM (3.2 Å) |
Seely SM, Basu RS, Gagnon MG |
(2024) "Mechanistic
insights into the alternative ribosome recycling by
HflXr." Nucleic Acids Res.,
52, 4053-4066. doi: 10.1093/nar/gkae128.
|
cryo-EM structure of the listeria innocua 70s ribosome
in complex with hflxr, hpf, and e-site trna (structure
ii-b) . SNAP output
|
|
8uu8
|
ribosome |
cryo-EM (3.1 Å) |
Seely SM, Basu RS, Gagnon MG |
(2024) "Mechanistic
insights into the alternative ribosome recycling by
HflXr." Nucleic Acids Res.,
52, 4053-4066. doi: 10.1093/nar/gkae128.
|
cryo-EM structure of the listeria innocua 70s ribosome
(head-swiveled) in complex with hflxr and pe-e-trna
(structure ii-c) . SNAP
output
|
|
8uu9
|
ribosome |
cryo-EM (3.1 Å) |
Seely SM, Basu RS, Gagnon MG |
(2024) "Mechanistic
insights into the alternative ribosome recycling by
HflXr." Nucleic Acids Res.,
52, 4053-4066. doi: 10.1093/nar/gkae128.
|
cryo-EM structure of the ratcheted listeria innocua 70s
ribosome (head-swiveled) in complex with hflxr and
pe-e-trna (structure ii-d) . SNAP output
|
|
8uua
|
ribosome |
cryo-EM (2.7 Å) |
Seely SM, Basu RS, Gagnon MG |
(2024) "Mechanistic
insights into the alternative ribosome recycling by
HflXr." Nucleic Acids Res.,
52, 4053-4066. doi: 10.1093/nar/gkae128.
|
cryo-EM structure of the listeria innocua 50s ribosomal
subunit in complex with hflxr (structure iii) .
SNAP output
|
|
8uvr
|
ribosome-inhibitor,antibiotic |
X-ray (2.6 Å) |
Phelps GA, Cheramie MN, Fernando DM, Selchow P, Meyer
CJ, Waidyarachchi SL, Dharuman S, Liu J, Meuli M, Molin
MD, Killam BY, Murphy PA, Reeve SM, Wilt LA, Anderson SM,
Yang L, Lee RB, Temrikar ZH, Lukka PB, Meibohm B,
Polikanov YS, Hobbie SN, Bottger EC, Sander P, Lee
RE |
(2024) "Development
of 2nd generation aminomethyl spectinomycins that
overcome native efflux in Mycobacterium abscessus."
Proc.Natl.Acad.Sci.USA, 121,
e2314101120. doi: 10.1073/pnas.2314101120.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with spectinomycin, mrna,
deacylated a- and e-site trnaphe, and deacylated p-site
trnamet at 2.60a resolution . SNAP output
|
|
8uvs
|
ribosome-inhibitor |
X-ray (2.75 Å) |
Phelps GA, Cheramie MN, Fernando DM, Selchow P, Meyer
CJ, Waidyarachchi SL, Dharuman S, Liu J, Meuli M, Molin
MD, Killam BY, Murphy PA, Reeve SM, Wilt LA, Anderson SM,
Yang L, Lee RB, Temrikar ZH, Lukka PB, Meibohm B,
Polikanov YS, Hobbie SN, Bottger EC, Sander P, Lee
RE |
(2024) "Development
of 2nd generation aminomethyl spectinomycins that
overcome native efflux in Mycobacterium abscessus."
Proc.Natl.Acad.Sci.USA, 121,
e2314101120. doi: 10.1073/pnas.2314101120.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with spectinomycin derivative
2694, mrna, deacylated a- and e-site trnaphe, and
deacylated p-site trnamet at 2.75a resolution .
SNAP output
|
|
8ux8
|
ribosome |
cryo-EM (3.6 Å) |
Kimbrough EM, Nguyen HA, Li H, Bailey NA, Ning W,
Mattingly JM, Gamper H, Hou YM, Gonzalez RL, Dunham
CM |
(2025) "An RNA modification prevents extended
codon-anticodon interactions from facilitating +1
frameshifting." Nat Commun. |
E. coli 70s ribosome with unmodified lys-trnapro(ggg)
bound to slippery p-site ccc-c codon in the +1 mrna
reading frame . SNAP
output
|
|
8uxb
|
ribosome |
cryo-EM (2.9 Å) |
Kimbrough EM, Nguyen HA, Li H, Bailey NA, Ning W,
Mattingly JM, Gamper H, Hou YM, Gonzalez RL, Dunham
CM |
(2025) "An RNA modification prevents extended
codon-anticodon interactions from facilitating +1
frameshifting." Nat Commun. |
E. coli 70s ribosome with unmodified p-e-trnapro(ggg)
bound to slippery p-site ccc-c codon . SNAP output
|
|
8uz3
|
ribosome |
cryo-EM (3.2 Å) |
Kimbrough EM, Nguyen HA, Li H, Bailey NA, Ning W,
Mattingly JM, Gamper H, Hou YM, Gonzalez RL, Dunham
CM |
(2025) "An RNA modification prevents extended
codon-anticodon interactions from facilitating +1
frameshifting." Nat Commun. |
E. coli 70s ribosome with unmodified e*-e-trnapro(ggg)
bound to slippery p-site ccc-c codon . SNAP output
|
|
8uzg
|
ribosome |
cryo-EM (3.7 Å) |
Kimbrough EM, Nguyen HA, Li H, Bailey NA, Ning W,
Mattingly JM, Gamper H, Hou YM, Gonzalez RL, Dunham
CM |
(2025) "An RNA modification prevents extended
codon-anticodon interactions from facilitating +1
frameshifting." Nat Commun. |
E. coli 70s ribosome with unmodified e*-e-trnapro(ggg)
bound to slippery p-site ccc-c codon . SNAP output
|
|
8v03
|
ribosome |
cryo-EM (4.0 Å) |
Kimbrough EM, Nguyen HA, Li H, Bailey NA, Ning W,
Mattingly JM, Gamper H, Hou YM, Gonzalez RL, Dunham
CM |
(2025) "An RNA modification prevents extended
codon-anticodon interactions from facilitating +1
frameshifting." Nat Commun. |
E. coli 70s ribosome with unmodified p-e-trnapro(ggg)
bound to slippery p-site ccc-c codon . SNAP output
|
|
8v83
|
ribosome |
cryo-EM (2.53 Å) |
Cruz VE, Weirich CS, Peddada N, Erzberger JP |
(2024) "The
DEAD-box ATPase Dbp10/DDX54 initiates peptidyl
transferase center formation during 60S ribosome
biogenesis." Nat Commun,
15, 3296. doi: 10.1038/s41467-024-47616-7.
|
60s ribosome biogenesis intermediate (dbp10
pre-catalytic structure - overall map) . SNAP output
|
|
8v84
|
ribosome-RNA |
cryo-EM (2.7 Å) |
Cruz VE, Weirich CS, Peddada N, Erzberger JP |
(2024) "The
DEAD-box ATPase Dbp10/DDX54 initiates peptidyl
transferase center formation during 60S ribosome
biogenesis." Nat Commun,
15, 3296. doi: 10.1038/s41467-024-47616-7.
|
60s ribosome biogenesis intermediate (dbp10 catalytic
structure - overall map) . SNAP output
|
|
8v87
|
ribosome-RNA |
cryo-EM (2.66 Å) |
Cruz VE, Weirich CS, Peddada N, Erzberger JP |
(2024) "The
DEAD-box ATPase Dbp10/DDX54 initiates peptidyl
transferase center formation during 60S ribosome
biogenesis." Nat Commun,
15, 3296. doi: 10.1038/s41467-024-47616-7.
|
60s ribosome biogenesis intermediate (dbp10
post-catalytic structure - overall map) . SNAP output
|
|
8v9j
|
ribosome |
cryo-EM (3.1 Å) |
Helena-Bueno K, Rybak MY, Ekemezie CL, Sullivan R,
Brown CR, Dingwall C, Basle A, Schneider C, Connolly JPR,
Blaza JN, Csorgo B, Moynihan PJ, Gagnon MG, Hill CH,
Melnikov SV |
(2024) "A new
family of bacterial ribosome hibernation factors."
Nature, 626, 1125-1132. doi:
10.1038/s41586-024-07041-8.
|
cryo-EM structure of the mycobacterium smegmatis 70s
ribosome in complex with hibernation factor msmeg1130
(balon) (structure 4) . SNAP output
|
|
8v9k
|
ribosome |
cryo-EM (3.1 Å) |
Helena-Bueno K, Rybak MY, Ekemezie CL, Sullivan R,
Brown CR, Dingwall C, Basle A, Schneider C, Connolly JPR,
Blaza JN, Csorgo B, Moynihan PJ, Gagnon MG, Hill CH,
Melnikov SV |
(2024) "A new
family of bacterial ribosome hibernation factors."
Nature, 626, 1125-1132. doi:
10.1038/s41586-024-07041-8.
|
cryo-EM structure of the mycobacterium smegmatis 70s
ribosome in complex with hibernation factor rv2629
(balon) (structure 5) . SNAP output
|
|
8v9l
|
ribosome |
cryo-EM (3.0 Å) |
Helena-Bueno K, Rybak MY, Ekemezie CL, Sullivan R,
Brown CR, Dingwall C, Basle A, Schneider C, Connolly JPR,
Blaza JN, Csorgo B, Moynihan PJ, Gagnon MG, Hill CH,
Melnikov SV |
(2024) "A new
family of bacterial ribosome hibernation factors."
Nature, 626, 1125-1132. doi:
10.1038/s41586-024-07041-8.
|
cryo-EM structure of the mycobacterium smegmatis 70s
ribosome in complex with hibernation factor msmeg1130
(balon) and msmegef-tu(gdp) (composite structure 6) .
SNAP output
|
|
8vaj
|
RNA binding protein-RNA |
X-ray (3.45 Å) |
Zhang H, Sim G, Kehling AC, Adhav VA, Savidge A,
Pastore B, Tang W, Nakanishi K |
(2024) "Target
cleavage and gene silencing by Argonautes with
cityRNAs." Cell Rep, 43,
114806. doi: 10.1016/j.celrep.2024.114806.
|
Human argonaute3 bound to cityrna and target RNA .
SNAP output
|
|
8ves
|
hydrolase |
cryo-EM (3.22 Å) |
Wu R, Ingle S, Barnes SA, Dahlin HR, Khamrui S, Xiang
Y, Shi Y, Bechhofer DH, Lazarus MB |
(2024) "Structural
insights into RNA cleavage by a novel family of
bacterial RNases." Nucleic Acids Res.,
52, 10705-10716. doi: 10.1093/nar/gkae717.
|
Structure of yicc endoribonuclease bound to an RNA
substrate . SNAP
output
|
|
8vft
|
ribosome |
cryo-EM (3.3 Å) |
Murray J, Shao S |
"Structure of emetine-stalled ribosome." |
Translating 80s rabbit ribosome stalled by emetine with
eef2 . SNAP output
|
|
8vio
|
ribosome |
cryo-EM (3.26 Å) |
Majumdar S, Kashyap A, Koripella RK, Sharma MR,
Hurst-Hess K, Manjari SR, Banavali NK, Ghosh P, Agrawal
RK |
(2025) "HflX-mediated
drug resistance through ribosome splitting and rRNA
disordering in mycobacteria."
Proc.Natl.Acad.Sci.USA, 122,
e2419826122. doi: 10.1073/pnas.2419826122.
|
Structure of mycobacterium smegmatis hflx bound to a
70s ribosome . SNAP
output
|
|
8viv
|
RNA binding protein |
X-ray (2.2 Å) |
Qiu C, Crittenden SL, Carrick BH, Dillard LB, Costa
Dos Santos SJ, Dandey VP, Dutcher RC, Viverette EG, Wine
RN, Woodworth J, Campbell ZT, Wickens M, Borgnia MJ,
Kimble J, Hall TMT |
(2025) "A higher
order PUF complex is central to regulation of C.
elegans germline stem cells." Nat Commun,
16, 123. doi: 10.1038/s41467-024-55526-x.
|
Crystal structure of fbf-2 rbd in complex with gld-1
fbea* RNA . SNAP
output
|
|
8vk0
|
ribosome |
cryo-EM (3.14 Å) |
Majumdar S, Kashyap A, Koripella RK, Sharma MR,
Hurst-Hess K, Manjari SR, Banavali NK, Ghosh P, Agrawal
RK |
(2025) "HflX-mediated
drug resistance through ribosome splitting and rRNA
disordering in mycobacteria."
Proc.Natl.Acad.Sci.USA, 122,
e2419826122. doi: 10.1073/pnas.2419826122.
|
Structure of mycobacterium smegmatis 50s ribosomal
subunit bound to hflx:50s-hflx-a . SNAP output
|
|
8vk7
|
ribosome |
cryo-EM (3.09 Å) |
Majumdar S, Kashyap A, Koripella RK, Sharma MR,
Hurst-Hess K, Manjari SR, Banavali NK, Ghosh P, Agrawal
RK |
(2025) "HflX-mediated
drug resistance through ribosome splitting and rRNA
disordering in mycobacteria."
Proc.Natl.Acad.Sci.USA, 122,
e2419826122. doi: 10.1073/pnas.2419826122.
|
Structure of mycobacterium smegmatis 50s ribosomal
subunit bound to hflx:50s-hflx-b . SNAP output
|
|
8vki
|
ribosome |
cryo-EM (2.96 Å) |
Majumdar S, Kashyap A, Koripella RK, Sharma MR,
Hurst-Hess K, Manjari SR, Banavali NK, Ghosh P, Agrawal
RK |
(2025) "HflX-mediated
drug resistance through ribosome splitting and rRNA
disordering in mycobacteria."
Proc.Natl.Acad.Sci.USA, 122,
e2419826122. doi: 10.1073/pnas.2419826122.
|
Structure of mycobacterium smegmatis 50s ribosomal
subunit bound to hflx:50s-hflx-c . SNAP output
|
|
8vkw
|
ribosome |
cryo-EM (3.44 Å) |
Majumdar S, Kashyap A, Koripella RK, Sharma MR,
Hurst-Hess K, Manjari SR, Banavali NK, Ghosh P, Agrawal
RK |
(2025) "HflX-mediated
drug resistance through ribosome splitting and rRNA
disordering in mycobacteria."
Proc.Natl.Acad.Sci.USA, 122,
e2419826122. doi: 10.1073/pnas.2419826122.
|
Structure of mycobacterium smegmatis 50s ribosomal
subunit bound to delnte-hflx . SNAP output
|
|
8vm8
|
RNA-immune system |
X-ray (1.54 Å) |
Das NK, Vogt J, Patel A, Banna HA, Koirala D |
(2024) "Structural
basis for a highly conserved RNA-mediated enteroviral
genome replication." Nucleic Acids Res.,
52, 11218-11233. doi: 10.1093/nar/gkae627.
|
The crystal structure of coxsackievirus b3 RNA
replication element sd-loop mutant in complex with fab
bl3-6 . SNAP output
|
|
8vm9
|
RNA-immune system |
X-ray (2.2 Å) |
Das NK, Vogt J, Patel A, Banna HA, Koirala D |
(2024) "Structural
basis for a highly conserved RNA-mediated enteroviral
genome replication." Nucleic Acids Res.,
52, 11218-11233. doi: 10.1093/nar/gkae627.
|
The crystal structure of rhinovirus b14 RNA replication
element sd-loop mutant in complex with fab bl3-6 .
SNAP output
|
|
8vma
|
RNA-immune system |
X-ray (2.54 Å) |
Das NK, Vogt J, Patel A, Banna HA, Koirala D |
(2024) "Structural
basis for a highly conserved RNA-mediated enteroviral
genome replication." Nucleic Acids Res.,
52, 11218-11233. doi: 10.1093/nar/gkae627.
|
The crystal structure of rhinovirus c15 RNA replication
element sd-loop mutant in complex with fab bl3-6 .
SNAP output
|
|
8vmb
|
RNA-immune system |
X-ray (2.97 Å) |
Das NK, Vogt J, Patel A, Banna HA, Koirala D |
(2024) "Structural
basis for a highly conserved RNA-mediated enteroviral
genome replication." Nucleic Acids Res.,
52, 11218-11233. doi: 10.1093/nar/gkae627.
|
The crystal structure of rhinovirus c15 RNA replication
element sb-loop mutant in complex with fab bl3-6 .
SNAP output
|
|
8vpk
|
ribosome |
cryo-EM (2.63 Å) |
Majumdar S, Kashyap A, Koripella RK, Sharma MR,
Hurst-Hess K, Manjari SR, Banavali NK, Ghosh P, Agrawal
RK |
(2025) "HflX-mediated
drug resistance through ribosome splitting and rRNA
disordering in mycobacteria."
Proc.Natl.Acad.Sci.USA, 122,
e2419826122. doi: 10.1073/pnas.2419826122.
|
Structure of mycobacterium smegmatis 50s ribosomal
subunit bound to hflx and erythromycin:50s-hflx-b-ery .
SNAP output
|
|
8vr4
|
ribosome |
cryo-EM (2.8 Å) |
Majumdar S, Kashyap A, Koripella RK, Sharma MR,
Hurst-Hess K, Manjari SR, Banavali NK, Ghosh P, Agrawal
RK |
(2025) "HflX-mediated
drug resistance through ribosome splitting and rRNA
disordering in mycobacteria."
Proc.Natl.Acad.Sci.USA, 122,
e2419826122. doi: 10.1073/pnas.2419826122.
|
Structure of mycobacterium smegmatis 50s ribosomal
subunit bound to hflx and erythromycin:50s-hflx-a-ery .
SNAP output
|
|
8vr8
|
ribosome |
cryo-EM (3.25 Å) |
Majumdar S, Kashyap A, Koripella RK, Sharma MR,
Hurst-Hess K, Manjari SR, Banavali NK, Ghosh P, Agrawal
RK |
(2025) "HflX-mediated
drug resistance through ribosome splitting and rRNA
disordering in mycobacteria."
Proc.Natl.Acad.Sci.USA, 122,
e2419826122. doi: 10.1073/pnas.2419826122.
|
Structure of mycobacterium smegmatis 50s ribosomal
subunit bound to hflx and
chloramphenicol:50s-hflx-b-clm . SNAP output
|
|
8vrl
|
ribosome |
cryo-EM (3.33 Å) |
Majumdar S, Kashyap A, Koripella RK, Sharma MR,
Hurst-Hess K, Manjari SR, Banavali NK, Ghosh P, Agrawal
RK |
(2025) "HflX-mediated
drug resistance through ribosome splitting and rRNA
disordering in mycobacteria."
Proc.Natl.Acad.Sci.USA, 122,
e2419826122. doi: 10.1073/pnas.2419826122.
|
Structure of mycobacterium smegmatis 50s ribosomal
subunit bound to hflx and
chloramphenicol:50s-hflx-a-clm . SNAP output
|
|
8vs9
|
ribosome |
cryo-EM (3.9 Å) |
Teran D, Zhang Y, Korostelev AA |
(2024) "Endogenous
trans-translation structure visualizes the decoding of
the first tmRNA alanine codon." Front
Microbiol, 15, 1369760. doi:
10.3389/fmicb.2024.1369760.
|
Endogenous trans-translation complex with tmrna*smpb in
the p site and alanyl-trna in the a site and
deacyl-trna in the e site of e. coli 70s ribosome .
SNAP output
|
|
8vsa
|
ribosome |
cryo-EM (3.7 Å) |
Teran D, Zhang Y, Korostelev AA |
(2024) "Endogenous
trans-translation structure visualizes the decoding of
the first tmRNA alanine codon." Front
Microbiol, 15, 1369760. doi:
10.3389/fmicb.2024.1369760.
|
Endogenous trans-translation complex with tmrna*smpb in
the p site and alanyl-trna in the a site of e. coli 70s
ribosome . SNAP
output
|
|
8vtu
|
ribosome |
X-ray (2.4 Å) |
Aleksandrova EV, Ma CX, Klepacki D, Alizadeh F,
Vazquez-Laslop N, Liang JH, Polikanov YS, Mankin AS |
(2024) "Macrolones
target bacterial ribosomes and DNA gyrase and can evade
resistance mechanisms." Nat.Chem.Biol.,
20, 1680-1690. doi: 10.1038/s41589-024-01685-3.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with macrolone mcx-66, mrna,
aminoacylated a-site phe-trnaphe, aminoacylated p-site
fmet-trnamet, and deacylated e-site trnaphe at 2.40a
resolution . SNAP
output
|
|
8vtv
|
ribosome |
X-ray (2.55 Å) |
Aleksandrova EV, Ma CX, Klepacki D, Alizadeh F,
Vazquez-Laslop N, Liang JH, Polikanov YS, Mankin AS |
(2024) "Macrolones
target bacterial ribosomes and DNA gyrase and can evade
resistance mechanisms." Nat.Chem.Biol.,
20, 1680-1690. doi: 10.1038/s41589-024-01685-3.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with macrolone mcx-91, mrna,
aminoacylated a-site phe-trnaphe, aminoacylated p-site
fmet-trnamet, and deacylated e-site trnaphe at 2.55a
resolution . SNAP
output
|
|
8vtw
|
ribosome |
X-ray (2.35 Å) |
Aleksandrova EV, Ma CX, Klepacki D, Alizadeh F,
Vazquez-Laslop N, Liang JH, Polikanov YS, Mankin AS |
(2024) "Macrolones
target bacterial ribosomes and DNA gyrase and can evade
resistance mechanisms." Nat.Chem.Biol.,
20, 1680-1690. doi: 10.1038/s41589-024-01685-3.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with macrolone mcx-128 and
protein y at 2.35a resolution . SNAP output
|
|
8vtx
|
ribosome |
X-ray (2.4 Å) |
Aleksandrova EV, Ma CX, Klepacki D, Alizadeh F,
Vazquez-Laslop N, Liang JH, Polikanov YS, Mankin AS |
(2024) "Macrolones
target bacterial ribosomes and DNA gyrase and can evade
resistance mechanisms." Nat.Chem.Biol.,
20, 1680-1690. doi: 10.1038/s41589-024-01685-3.
|
Crystal structure of the a2058-n6-dimethylated thermus
thermophilus 70s ribosome in complex with macrolone
mcx-128, mrna, aminoacylated a-site phe-trnaphe,
aminoacylated p-site fmet-trnamet, and deacylated
e-site trnaphe at 2.40a resolution . SNAP output
|
|
8vty
|
ribosome-antibiotic |
X-ray (2.6 Å) |
Aleksandrova EV, Ma CX, Klepacki D, Alizadeh F,
Vazquez-Laslop N, Liang JH, Polikanov YS, Mankin AS |
(2024) "Macrolones
target bacterial ribosomes and DNA gyrase and can evade
resistance mechanisms." Nat.Chem.Biol.,
20, 1680-1690. doi: 10.1038/s41589-024-01685-3.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with ciprofloxacin and protein
y at 2.60a resolution . SNAP output
|
|
8vu0
|
RNA binding protein-RNA |
X-ray (2.64 Å) |
Umuhire Juru A, Ghirlando R, Zhang J |
(2024) "Structural
basis of tRNA recognition by the widespread OB
fold." Nat Commun, 15,
6385. doi: 10.1038/s41467-024-50730-1.
|
Co-crystal structure of aquifex aeolicus trbp111 in
complex with e. coli trna-ile . SNAP output
|
|
8vuo
|
viral protein |
X-ray (2.39 Å) |
Misra A, Rahisuddin R, Gupta YK |
"Crystal structure of SARS-CoV-2 nsp16/nsp10 in
complex with Cap-1 RNA." |
Crystal structure of sars-cov-2 nsp16-nsp10 in complex
with cap-1 RNA . SNAP
output
|
|
8vz6
|
toxin-RNA |
cryo-EM (3.56 Å) |
Zilberzwige-Tal S, Altae-Tran H, Kannan S, Wilkinson
ME, Vo SC, Shmakov S, Yao CJ, Strebinger D, Edmonds KK,
Mears KS, Makarova KS, Macrae RK, Koonin EV, Zhang F |
"Emergence of a CRISPR RNA-guiding mechanism from a
type III toxin-antitoxin system." |
Pbabif dimer bound to ncrna . SNAP output
|
|
8w1o
|
viral protein |
cryo-EM (2.8 Å) |
Xia X, Sung PY, Martynowycz MW, Gonen T, Roy P, Zhou
ZH |
(2024) "RNA
genome packaging and capsid assembly of bluetongue
virus visualized in host cells." Cell,
187, 2236-2249.e17. doi: 10.1016/j.cell.2024.03.007.
|
cryo-EM structure of btv virion . SNAP output
|
|
8w2o
|
splicing |
cryo-EM (3.49 Å) |
Chalivendra S, Shi S, Li X, Kuang Z, Giovinazzo J,
Zhang L, Rossi J, Wang J, Saviola AJ, Welty R, Liu S,
Vaeth KF, Zhou ZH, Hansen KC, Taliaferro JM, Zhao R |
(2024) "Selected
humanization of yeast U1 snRNP leads to global
suppression of pre-mRNA splicing and mitochondrial
dysfunction in the budding yeast." Rna,
30, 1070-1088. doi: 10.1261/rna.079917.123.
|
Yeast u1 snrnp with humanized u1c zinc-finger domain .
SNAP output
|
|
8w2s
|
immune system-RNA |
cryo-EM (3.4 Å) |
Ocampo RF, Bravo JPK, Dangerfield TL, Nocedal I,
Jirde SA, Alexander LM, Thomas NC, Das A, Nielson S,
Johnson KA, Brown CT, Butterfield CN, Goltsman DSA,
Taylor DW |
(2025) "DNA
targeting by compact Cas9d and its resurrected
ancestor." Nat Commun,
16, 457. doi: 10.1038/s41467-024-55573-4.
|
Cas9d effector:sgrna binary complex . SNAP output
|
|
8w35
|
RNA binding protein |
cryo-EM (2.61 Å) |
Birkholz N, Kamata K, Feussner M, Wilkinson ME, Cuba
Samaniego C, Migur A, Kimanius D, Ceelen M, Went SC,
Usher B, Blower TR, Brown CM, Beisel CL, Weinberg Z,
Fagerlund RD, Jackson SA, Fineran PC |
(2024) "Phage
anti-CRISPR control by an RNA- and DNA-binding
helix-turn-helix protein." Nature,
631, 670-677. doi: 10.1038/s41586-024-07644-1.
|
Aca2 from pectobacterium phage zf40 bound to RNA .
SNAP output
|
|
8w51
|
ribosome |
cryo-EM (2.4 Å) |
Li X, Yu T, Li Q, Zeng F |
"Structure basis of translation regulation by YchF
bound to ribosome." |
Structure of ychf(h114a) on e.coli 50s ribosomal
subunit . SNAP
output
|
|
8wce
|
RNA binding protein-RNA |
cryo-EM (3.09 Å) |
Chen F, Zhang C, Xue J, Wang F, Li Z |
(2024) "Molecular
mechanism for target RNA recognition and cleavage of
Cas13h." Nucleic Acids Res.,
52, 7279-7291. doi: 10.1093/nar/gkae324.
|
cryo-EM structure of a protein-RNA complex . SNAP output
|
|
8wcs
|
RNA binding protein-RNA |
cryo-EM (3.1 Å) |
Chen F, Zhang C, Xue J, Wang F, Li Z |
(2024) "Molecular
mechanism for target RNA recognition and cleavage of
Cas13h." Nucleic Acids Res.,
52, 7279-7291. doi: 10.1093/nar/gkae324.
|
cryo-EM structure of cas13h1-crrna binary complex .
SNAP output
|
|
8wf8
|
RNA binding protein-RNA |
cryo-EM (2.59 Å) |
Ishikawa J, Kato K, Kannan S, Okazaki S, Ishiguro S,
Yamashita K, Yachie N, Nishizawa T, Zhang F, Nishimasu
H |
(2025) "Structural
insights into RNA-guided RNA editing by the
Cas13b-ADAR2 complex."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-025-01529-1.
|
cryo-EM structure of the pspcas13b-crrna complex .
SNAP output
|
|
8wf9
|
RNA binding protein-RNA |
cryo-EM (3.13 Å) |
Ishikawa J, Kato K, Kannan S, Okazaki S, Ishiguro S,
Yamashita K, Yachie N, Nishizawa T, Zhang F, Nishimasu
H |
(2025) "Structural
insights into RNA-guided RNA editing by the
Cas13b-ADAR2 complex."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-025-01529-1.
|
cryo-EM structure of the pspcas13b-crrna-target RNA
complex (state 1) . SNAP
output
|
|
8wfa
|
RNA binding protein-RNA |
cryo-EM (3.13 Å) |
Ishikawa J, Kato K, Kannan S, Okazaki S, Ishiguro S,
Yamashita K, Yachie N, Nishizawa T, Zhang F, Nishimasu
H |
(2025) "Structural
insights into RNA-guided RNA editing by the
Cas13b-ADAR2 complex."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-025-01529-1.
|
cryo-EM structure of the pspcas13b-crrna-target RNA
complex (state 2) . SNAP
output
|
|
8wfb
|
RNA binding protein-RNA |
cryo-EM (3.71 Å) |
Ishikawa J, Kato K, Kannan S, Okazaki S, Ishiguro S,
Yamashita K, Yachie N, Nishizawa T, Zhang F, Nishimasu
H |
(2025) "Structural
insights into RNA-guided RNA editing by the
Cas13b-ADAR2 complex."
Nat.Struct.Mol.Biol. doi: 10.1038/s41594-025-01529-1.
|
cryo-EM structure of the dpspcas13b-adar2-crrna-target
RNA complex . SNAP
output
|
|
8wfx
|
RNA binding protein-RNA |
cryo-EM (3.73 Å) |
Zhang H, Shi M, Ma X, Liu M, Wang N, Lu Q, Li Z, Zhao
Y, Zhao H, Chen H, Zhang H, Jiang T, Ouyang S, Huo Y, Bi
L |
(2024) "Type-III-A
structure of mycobacteria CRISPR-Csm complexes
involving atypical crRNAs."
Int.J.Biol.Macromol., 260,
129331. doi: 10.1016/j.ijbiomac.2024.129331.
|
cryo-EM structure of crispr-csm effector complex from
mycobacterium canettii . SNAP output
|
|
8whx
|
ribosome |
cryo-EM (2.8 Å) |
Kumar N, Sharma S, Kaushal PS |
(2024) "Cryo- EM
structure of the mycobacterial 70S ribosome in complex
with ribosome hibernation promotion factor RafH."
Nat Commun, 15, 638. doi:
10.1038/s41467-024-44879-y.
|
Cryo- em structure of mycobacterium smegmatis 70s
ribosome and rafh. . SNAP output
|
|
8why
|
ribosome |
cryo-EM (2.7 Å) |
Kumar N, Sharma S, Kaushal PS |
(2024) "Cryo- EM
structure of the mycobacterial 70S ribosome in complex
with ribosome hibernation promotion factor RafH."
Nat Commun, 15, 638. doi:
10.1038/s41467-024-44879-y.
|
Cryo- em structure of mycobacterium smegmatis 50s
ribosomal subunit (body 1) of 70s ribosome and rafh. .
SNAP output
|
|
8wi7
|
ribosome |
cryo-EM (3.5 Å) |
Kumar N, Sharma S, Kaushal PS |
(2024) "Cryo- EM
structure of the mycobacterial 70S ribosome in complex
with ribosome hibernation promotion factor RafH."
Nat Commun, 15, 638. doi:
10.1038/s41467-024-44879-y.
|
Cryo- em structure of mycobacterium smegmatis 70s
ribosome, bs1 and rafh. . SNAP output
|
|
8wi8
|
ribosome |
cryo-EM (2.7 Å) |
Kumar N, Sharma S, Kaushal PS |
(2024) "Cryo- EM
structure of the mycobacterial 70S ribosome in complex
with ribosome hibernation promotion factor RafH."
Nat Commun, 15, 638. doi:
10.1038/s41467-024-44879-y.
|
Cryo- em structure of mycobacterium smegmatis 50s
ribosomal subunit (body 1) of 70s ribosome, bs1 and
rafh. . SNAP output
|
|
8wi9
|
ribosome |
cryo-EM (3.5 Å) |
Kumar N, Sharma S, Kaushal PS |
(2024) "Cryo- EM
structure of the mycobacterial 70S ribosome in complex
with ribosome hibernation promotion factor RafH."
Nat Commun, 15, 638. doi:
10.1038/s41467-024-44879-y.
|
Cryo- em structure of mycobacterium smegmatis 30s
ribosomal subunit (body 2) of 70s ribosome, bs1 and
rafh. . SNAP output
|
|
8wib
|
ribosome |
cryo-EM (3.5 Å) |
Kumar N, Sharma S, Kaushal PS |
(2024) "Cryo- EM
structure of the mycobacterial 70S ribosome in complex
with ribosome hibernation promotion factor RafH."
Nat Commun, 15, 638. doi:
10.1038/s41467-024-44879-y.
|
Cryo- em structure of mycobacterium smegmatis 70s
ribosome, e- trna and rafh. . SNAP output
|
|
8wic
|
ribosome |
cryo-EM (3.5 Å) |
Kumar N, Sharma S, Kaushal PS |
(2024) "Cryo- EM
structure of the mycobacterial 70S ribosome in complex
with ribosome hibernation promotion factor RafH."
Nat Commun, 15, 638. doi:
10.1038/s41467-024-44879-y.
|
Cryo- em structure of mycobacterium smegmatis 50s
ribosomal subunit (body 1) of 70s ribosome, e- trna and
rafh. . SNAP output
|
|
8wid
|
ribosome |
cryo-EM (3.5 Å) |
Kumar N, Sharma S, Kaushal PS |
(2024) "Cryo- EM
structure of the mycobacterial 70S ribosome in complex
with ribosome hibernation promotion factor RafH."
Nat Commun, 15, 638. doi:
10.1038/s41467-024-44879-y.
|
Cryo- em structure of mycobacterium smegmatis 30s
ribosomal subunit (body 2) of 70s ribosome, e- trna and
rafh. . SNAP output
|
|
8wif
|
ribosome |
cryo-EM (2.9 Å) |
Kumar N, Sharma S, Kaushal PS |
(2024) "Cryo- EM
structure of the mycobacterial 70S ribosome in complex
with ribosome hibernation promotion factor RafH."
Nat Commun, 15, 638. doi:
10.1038/s41467-024-44879-y.
|
Cryo- em structure of mycobacterium smegmatis 30s
ribosomal subunit (body 2) of 70s ribosome and rafh. .
SNAP output
|
|
8wkp
|
ribosome |
cryo-EM (4.62 Å) |
Wu Y, Ni MT, Wang YH, Wang C, Hou H, Zhang X, Zhou
J |
(2024) "Structural
basis of translation inhibition by a valine
tRNA-derived fragment." Life Sci Alliance,
7. doi: 10.26508/lsa.202302488.
|
Structural basis of translation inhibition by a valine
trna-derived fragment . SNAP output
|
|
8wm4
|
immune system |
cryo-EM (2.93 Å) |
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J,
Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X |
(2024) "Structural
basis of negative regulation of CRISPR-Cas7-11 by
TPR-CHAT." Signal Transduct Target Ther,
9, 111. doi: 10.1038/s41392-024-01821-4.
|
cryo-EM structure of dicas7-11 in complex with crrna .
SNAP output
|
|
8wmc
|
immune system |
cryo-EM (2.9 Å) |
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J,
Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X |
(2024) "Structural
basis of negative regulation of CRISPR-Cas7-11 by
TPR-CHAT." Signal Transduct Target Ther,
9, 111. doi: 10.1038/s41392-024-01821-4.
|
cryo-EM structure of dicas7-11-crrna in complex with
regulator . SNAP
output
|
|
8wmi
|
immune system |
cryo-EM (3.53 Å) |
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J,
Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X |
(2024) "Structural
basis of negative regulation of CRISPR-Cas7-11 by
TPR-CHAT." Signal Transduct Target Ther,
9, 111. doi: 10.1038/s41392-024-01821-4.
|
cryo-EM structure of dicas7-11 mutant in complex with
crrna . SNAP output
|
|
8wml
|
immune system |
cryo-EM (2.86 Å) |
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J,
Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X |
(2024) "Structural
basis of negative regulation of CRISPR-Cas7-11 by
TPR-CHAT." Signal Transduct Target Ther,
9, 111. doi: 10.1038/s41392-024-01821-4.
|
cryo-EM structure of cas7-11-crrna bound to n-terminal
of tpr-chat . SNAP
output
|
|
8wnd
|
ligase-RNA |
X-ray (2.8 Å) |
Chen B, Yi F, Luo Z, Lu F, Liu H, Luo S, Gu Q, Zhou
H |
(2024) "The
mechanism of discriminative aminoacylation by
isoleucyl-tRNA synthetase based on wobble nucleotide
recognition." Nat Commun,
15, 10817. doi: 10.1038/s41467-024-55183-0.
|
Crystal structure of saccharomyces cerevisiae
isoleucyl-trna synthetase in complex with trna(ile) and
isoleucine . SNAP
output
|
|
8wo8
|
RNA binding protein |
X-ray (2.78 Å) |
Kawai G, Okada K, Baba S, Sato A, Sakamoto T, Kanai
A |
(2024) "Homo-trimeric
structure of the ribonuclease for rRNA processing,
FAU-1, from Pyrococcus furiosus."
J.Biochem., 175, 671-676.
doi: 10.1093/jb/mvae010.
|
Crystal structure of an RNA-binding protein, fau-1,
from pyrococcus furiosus . SNAP output
|
|
8wq2
|
ribosome |
cryo-EM (4.1 Å) |
Wu Y, Ni MT, Wang YH, Wang C, Hou H, Zhang X, Zhou
J |
(2024) "Structural
basis of translation inhibition by a valine
tRNA-derived fragment." Life Sci Alliance,
7. doi: 10.26508/lsa.202302488.
|
Structural basis of translation inhibition by a valine
trna-derived fragment . SNAP output
|
|
8wq4
|
ribosome |
cryo-EM (4.53 Å) |
Wu Y, Ni MT, Wang YH, Wang C, Hou H, Zhang X, Zhou
J |
(2024) "Structural
basis of translation inhibition by a valine
tRNA-derived fragment." Life Sci Alliance,
7. doi: 10.26508/lsa.202302488.
|
Structural basis of translation inhibition by a valine
trna-derived fragment . SNAP output
|
|
8wrc
|
ribosome |
X-ray (3.59 Å) |
Yapici I, DeMirci H |
"Time-Resolved Kineto-Crystallography Reveals the
First Initiation Factor Ribosome Binding Dynamics." |
Time-resolved ambient temperature
kineto-crystallographic structure of initiation factor
in complex with ribosome . SNAP output
|
|
8wrt
|
RNA binding protein |
cryo-EM (3.31 Å) |
Kuo Z, Xi Z |
"Cryo-EM structure of Cas12-1/crRNA complex." |
cryo-EM structure of cas12-1-crrna complex . SNAP output
|
|
8wv1
|
ribosome |
X-ray (3.99 Å) |
DeMirci H, Tosun B |
"Ambient Temperature Structure of 50S Ribosomal
Subunit from Thermus Thermophilus." |
Ambient temperature structure of 50s ribosomal subunit
from thermus thermophilus . SNAP output
|
|
8wx0
|
transferase-RNA |
cryo-EM (3.7 Å) |
Wang N, Sheng Y, Liu Y, Guo Y, He J, Liu J |
(2024) "Cryo-EM
structures of Mycobacterium tuberculosis polynucleotide
phosphorylase suggest a potential mechanism for its RNA
substrate degradation."
Arch.Biochem.Biophys., 754,
109917. doi: 10.1016/j.abb.2024.109917.
|
Pnpase of m.tuberculosis with its RNA substrate .
SNAP output
|
|
8wzc
|
hydrolase-RNA |
X-ray (1.925 Å) |
Hong S, Choe J |
(2024) "Crystal
structure of NYN domain of Human KHNYN in complex with
single strand RNA."
Biochem.Biophys.Res.Commun.,
738, 150545. doi: 10.1016/j.bbrc.2024.150545.
|
Nyn domain of human khnyn complex with RNA . SNAP output
|
|
8x0n
|
RNA binding protein-RNA |
X-ray (2.8 Å) |
Xu Z, Liu Y, Li F, Yang Y, Zhang H, Meng F, Liu X,
Xie X, Chen X, Shi Y, Zhang L |
(2025) "Phase
separation of hnRNPA1 and TERRA regulates telomeric
stability." J Mol Cell Biol,
16. doi: 10.1093/jmcb/mjae037.
|
The molecular mechanism of hnrnpa1 recognize terra RNA.
. SNAP output
|
|
8x5d
|
RNA binding protein |
cryo-EM (3.1 Å) |
Zhang H, Shi M, Ma X, Liu M, Wang N, Lu Q, Li Z, Zhao
Y, Zhao H, Chen H, Zhang H, Jiang T, Ouyang S, Huo Y, Bi
L |
(2024) "Type-III-A
structure of mycobacteria CRISPR-Csm complexes
involving atypical crRNAs."
Int.J.Biol.Macromol., 260,
129331. doi: 10.1016/j.ijbiomac.2024.129331.
|
The cryo-EM structure of the mycobacterium tuberculosis
crispr-csm complex . SNAP output
|
|
8xc1
|
membrane protein |
cryo-EM (2.21 Å) |
Wang R, Cong Y, Qian D, Yan C, Gong D |
(2024) "Structural
basis for double-stranded RNA recognition by SID1."
Nucleic Acids Res., 52,
6718-6727. doi: 10.1093/nar/gkae395.
|
C. elegans sid1 in complex with dsrna . SNAP output
|
|
8xch
|
viral protein |
cryo-EM (3.4 Å) |
Yan L, Lou Z |
"Structural basis for template-product RNA duplex
unwinding by SARS-CoV-2 helicase." |
Sars-cov-2 replication-transcription complex has a
dimer-of-dimeric architecture (ddrtc) in pre-capping
initiation. . SNAP
output
|
|
8xi2
|
splicing |
cryo-EM (2.6 Å) |
Lu Y, Liang K, Zhan X |
(2025) "Structure
of a step II catalytically activated spliceosome from
Chlamydomonas reinhardtii." Embo J.,
44, 975-990. doi: 10.1038/s44318-024-00274-3.
|
cryo-EM structure of the chlamydomonas c* complex .
SNAP output
|
|
8xko
|
viral protein-RNA |
cryo-EM (3.29 Å) |
Jia X, Jing X, Li M, Gao M, Zhong Y, Li E, Liu Y, Li
R, Yao G, Liu Q, Zhou M, Hou Y, An L, Hong Y, Li S, Zhang
J, Wang W, Zhang K, Gong P, Chiu S |
(2024) "An
adenosine analog shows high antiviral potency against
coronavirus and arenavirus mainly through an unusual
base pairing mode." Nat Commun,
15, 10750. doi: 10.1038/s41467-024-54918-3.
|
Cryoem structure of compound hnc-1664 bound with
rdrp-RNA complex of sars-cov-2 . SNAP output
|
|
8xpo
|
replication |
cryo-EM (3.02 Å) |
Jia X, Jing X, Li M, Gao M, Zhong Y, Li E, Liu Y, Li
R, Yao G, Liu Q, Zhou M, Hou Y, An L, Hong Y, Li S, Zhang
J, Wang W, Zhang K, Gong P, Chiu S |
(2024) "An
adenosine analog shows high antiviral potency against
coronavirus and arenavirus mainly through an unusual
base pairing mode." Nat Commun,
15, 10750. doi: 10.1038/s41467-024-54918-3.
|
cryo-EM structure of lassa virus rdrp elongation
complex with the ntp form of compound hnc-1664 bound in
the active site . SNAP
output
|
|
8xpp
|
replication |
X-ray (3.0 Å) |
Jia X, Jing X, Li M, Gao M, Zhong Y, Li E, Liu Y, Li
R, Yao G, Liu Q, Zhou M, Hou Y, An L, Hong Y, Li S, Zhang
J, Wang W, Zhang K, Gong P, Chiu S |
(2024) "An
adenosine analog shows high antiviral potency against
coronavirus and arenavirus mainly through an unusual
base pairing mode." Nat Commun,
15, 10750. doi: 10.1038/s41467-024-54918-3.
|
Crystal structure of the enterovirus 71 rdrp elongation
complex with the nucleoside monophosphate form of
compound hnc-1664 at product position -1
(post-translocation state) . SNAP output
|
|
8xt0
|
ribosome |
cryo-EM (3.2 Å) |
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R,
Cheng J |
(2024) "Structural
basis for differential inhibition of eukaryotic
ribosomes by tigecycline." Nat Commun,
15, 5481. doi: 10.1038/s41467-024-49797-7.
|
cryo-EM structure of the human 55s mitoribosome with
5um tigecycline . SNAP
output
|
|
8xt1
|
ribosome |
cryo-EM (3.1 Å) |
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R,
Cheng J |
(2024) "Structural
basis for differential inhibition of eukaryotic
ribosomes by tigecycline." Nat Commun,
15, 5481. doi: 10.1038/s41467-024-49797-7.
|
cryo-EM structure of the human 39s mitoribosome with
5um tigecycline . SNAP
output
|
|
8xt2
|
ribosome |
cryo-EM (3.3 Å) |
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R,
Cheng J |
(2024) "Structural
basis for differential inhibition of eukaryotic
ribosomes by tigecycline." Nat Commun,
15, 5481. doi: 10.1038/s41467-024-49797-7.
|
cryo-EM structure of the human 55s mitoribosome with
10um tigecycline . SNAP
output
|
|
8xt3
|
ribosome |
cryo-EM (3.1 Å) |
Li X, Wang M, Denk T, Buschauer R, Li Y, Beckmann R,
Cheng J |
(2024) "Structural
basis for differential inhibition of eukaryotic
ribosomes by tigecycline." Nat Commun,
15, 5481. doi: 10.1038/s41467-024-49797-7.
|
cryo-EM structure of the human 39s mitoribosome with
10um tigecycline . SNAP
output
|
|
8xu8
|
translation |
cryo-EM (3.4 Å) |
Cheng J, Wu C, Li J, Yang Q, Zhao M, Zhang X |
(2025) "Capturing
eukaryotic ribosome dynamics in situ at high
resolution." Nat.Struct.Mol.Biol.,
32, 698-708. doi: 10.1038/s41594-024-01454-9.
|
State 2c(s2c) of yeast 80s ribosome bound to compact
eef2 and 2 trnas during peptidyl transferation .
SNAP output
|
|
8xz3
|
ribosome |
cryo-EM (3.6 Å) |
Srinivasan K, Banerjee A, Sengupta J |
(2024) "Cryo-EM
structures reveal the molecular mechanism of
HflX-mediated erythromycin resistance in
mycobacteria." Structure,
32, 1443. doi: 10.1016/j.str.2024.06.016.
|
Mycobacterium smegmatis 50s ribosomal subunit with
erythromycin . SNAP
output
|
|
8y03
|
RNA binding protein |
X-ray (2.93 Å) |
Chen J, Lin X, Xiang W, Chen Y, Zhao Y, Huang L, Liu
L |
(2025) "DNA
target binding-induced pre-crRNA processing in type II
and V CRISPR-Cas systems." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1241.
|
Crystal structure of lbcas12a-crrna complex . SNAP output
|
|
8y0u
|
ribosome |
cryo-EM (3.59 Å) |
Du M, Li X, Dong W, Zeng F |
(2024) "Implication
of Stm1 in the protection of eIF5A, eEF2 and tRNA
through dormant ribosomes." Front Mol
Biosci, 11, 1395220. doi:
10.3389/fmolb.2024.1395220.
|
Dormant ribosome with stm1 . SNAP output
|
|
8y2o
|
RNA binding protein-RNA |
cryo-EM (2.66 Å) |
Ishiguro K, Fujimura A, Shirouzu M |
(2025) "Structural
insights into tRNA recognition of the human FTSJ1-THADA
complex." Commun Biol, 8,
893. doi: 10.1038/s42003-025-08278-3.
|
The cryo-EM structure of human trna methyltransferase
ftsj1-thada with substrate trna and s-adenosyl
homocysteine (sah) . SNAP output
|
|
8y36
|
ribosome |
cryo-EM (2.65 Å) |
Ma CX, Li Y, Liu WT, Li Y, Zhao F, Lian XT, Ding J,
Liu SM, Liu XP, Fan BZ, Liu LY, Xue F, Li J, Zhang JR,
Xue Z, Pei XT, Lin JZ, Liang JH |
(2024) "Synthetic
macrolides overcoming MLS B K-resistant pathogens."
Cell Discov, 10, 75. doi:
10.1038/s41421-024-00702-y.
|
cryo-EM structure of staphylococcus aureus(atcc 29213)
50s ribosome in complex with mcx-190. . SNAP output
|
|
8y37
|
ribosome |
cryo-EM (2.53 Å) |
Ma CX, Li Y, Liu WT, Li Y, Zhao F, Lian XT, Ding J,
Liu SM, Liu XP, Fan BZ, Liu LY, Xue F, Li J, Zhang JR,
Xue Z, Pei XT, Lin JZ, Liang JH |
(2024) "Synthetic
macrolides overcoming MLS B K-resistant pathogens."
Cell Discov, 10, 75. doi:
10.1038/s41421-024-00702-y.
|
cryo-EM structure of staphylococcus aureus (15b196) 50s
ribosome in complex with mcx-190. . SNAP output
|
|
8y38
|
ribosome |
cryo-EM (2.58 Å) |
Ma CX, Li Y, Liu WT, Li Y, Zhao F, Lian XT, Ding J,
Liu SM, Liu XP, Fan BZ, Liu LY, Xue F, Li J, Zhang JR,
Xue Z, Pei XT, Lin JZ, Liang JH |
(2024) "Synthetic
macrolides overcoming MLS B K-resistant pathogens."
Cell Discov, 10, 75. doi:
10.1038/s41421-024-00702-y.
|
cryo-EM structure of staphylococcus aureus 70s ribosome
(strain 15b196) in complex with mcx-190. . SNAP output
|
|
8y39
|
ribosome |
cryo-EM (3.6 Å) |
Ma CX, Li Y, Liu WT, Li Y, Zhao F, Lian XT, Ding J,
Liu SM, Liu XP, Fan BZ, Liu LY, Xue F, Li J, Zhang JR,
Xue Z, Pei XT, Lin JZ, Liang JH |
(2024) "Synthetic
macrolides overcoming MLS B K-resistant pathogens."
Cell Discov, 10, 75. doi:
10.1038/s41421-024-00702-y.
|
cryo-EM structure of staphylococcus aureus(atcc 29213)
70s ribosome in complex with mcx-190. . SNAP output
|
|
8y6o
|
splicing-RNA |
cryo-EM (3.38 Å) |
Bai R, Yuan M, Zhang P, Luo T, Shi Y, Wan R |
(2024) "Structural
basis of U12-type intron engagement by the fully
assembled human minor spliceosome."
Science, 383, 1245-1252. doi:
10.1126/science.adn7272.
|
cryo-EM structure of the human minor pre-b complex
(pre-precatalytic spliceosome) u11 and tri-snrnp part .
SNAP output
|
|
8y7e
|
splicing-RNA |
cryo-EM (4.66 Å) |
Bai R, Yuan M, Zhang P, Luo T, Shi Y, Wan R |
(2024) "Structural
basis of U12-type intron engagement by the fully
assembled human minor spliceosome."
Science, 383, 1245-1252. doi:
10.1126/science.adn7272.
|
cryo-EM structure of the human minor pre-b complex
(pre-precatalytic spliceosome) u12 snrnp part .
SNAP output
|
|
8y7g
|
hydrolase |
X-ray (3.15 Å) |
Zhang D, Du L, Gao H, Yuan C, Lin Z |
(2024) "Structural
insight into the Csx1-Crn2 fusion self-limiting
ribonuclease of type III CRISPR system."
Nucleic Acids Res., 52,
8419-8430. doi: 10.1093/nar/gkae569.
|
Crystal structure of the marinitoga sp. csx1-crn2 h495a
mutant in complex with cyclic-tetraadenylate (ca4) .
SNAP output
|
|
8y9j
|
viral protein-RNA |
cryo-EM (4.6 Å) |
Fujita-Fujiharu Y, Hu S, Hirabayashi A, Takamatsu Y,
Ng YN, Houri K, Muramoto Y, Nakano M, Sugita Y, Noda
T |
(2025) "Structural
basis for Ebola virus nucleocapsid assembly and
function regulated by VP24." Nat Commun,
16, 2171. doi: 10.1038/s41467-025-57236-4.
|
Structure of the ebola virus nucleocapsid subunit .
SNAP output
|
|
8y9l
|
immune system-RNA |
cryo-EM (3.0 Å) |
Zheng W, Li H, Liu M, Wei Y, Liu B, Li Z, Xiong C,
Huang S, Hu C, Ouyang S |
(2025) "Molecular
insights and rational engineering of a compact
CRISPR-Cas effector Cas12h1 with a broad-spectrum
PAM." Signal Transduct Target Ther,
10, 66. doi: 10.1038/s41392-025-02147-5.
|
Cas12h1-crrna binary complex . SNAP output
|
|
8yb6
|
RNA binding protein-RNA |
cryo-EM (3.06 Å) |
Zhang C, Chen F, Wang F, Xu H, Xue J, Li Z |
(2024) "Mechanisms
for HNH-mediated target DNA cleavage in type I
CRISPR-Cas systems." Mol.Cell,
84, 3141. doi: 10.1016/j.molcel.2024.06.033.
|
Type i-ehnh cascade complex . SNAP output
|
|
8ye6
|
immune system-RNA |
cryo-EM (2.95 Å) |
Zheng J, Zhu Y, Huang T, Gao W, He J, Huang Z |
(2024) "Inhibition
mechanisms of CRISPR-Cas9 by AcrIIA25.1 and
AcrIIA32." Sci China Life Sci,
67, 1781-1791. doi: 10.1007/s11427-024-2607-8.
|
cryo-EM structure of cas9-sgrna-a32 complex . SNAP output
|
|
8ye9
|
immune system-RNA |
cryo-EM (3.43 Å) |
Zheng J, Zhu Y, Huang T, Gao W, He J, Huang Z |
(2024) "Inhibition
mechanisms of CRISPR-Cas9 by AcrIIA25.1 and
AcrIIA32." Sci China Life Sci,
67, 1781-1791. doi: 10.1007/s11427-024-2607-8.
|
cryo-EM structure of cas9-sgrna-a25 complex . SNAP output
|
|
8yh9
|
RNA binding protein-RNA |
cryo-EM (3.35 Å) |
Zhang C, Chen F, Wang F, Xu H, Xue J, Li Z |
(2024) "Mechanisms
for HNH-mediated target DNA cleavage in type I
CRISPR-Cas systems." Mol.Cell,
84, 3141. doi: 10.1016/j.molcel.2024.06.033.
|
Type i-fhnh cascade complex . SNAP output
|
|
8yhd
|
antiviral protein |
cryo-EM (2.93 Å) |
Yang J, Li X, He Q, Wang X, Tang J, Wang T, Zhang Y,
Yu F, Zhang S, Liu Z, Zhang L, Liao F, Yin H, Zhao H,
Deng Z, Zhang H |
(2024) "Structural
basis for the activity of the type VII CRISPR-Cas
system." Nature, 633,
465-472. doi: 10.1038/s41586-024-07815-0.
|
cryo-EM structure of ctr-bound type vii crispr-cas
complex at post-state i . SNAP output
|
|
8yhe
|
antiviral protein |
cryo-EM (3.07 Å) |
Yang J, Li X, He Q, Wang X, Tang J, Wang T, Zhang Y,
Yu F, Zhang S, Liu Z, Zhang L, Liao F, Yin H, Zhao H,
Deng Z, Zhang H |
(2024) "Structural
basis for the activity of the type VII CRISPR-Cas
system." Nature, 633,
465-472. doi: 10.1038/s41586-024-07815-0.
|
cryo-EM structure of ctr-bound type vii crispr-cas
complex at post-state ii . SNAP output
|
|
8yig
|
structural protein-RNA |
cryo-EM (3.15 Å) |
Cao N, Wang J, Deng T, Fan B, Su S, Ma J, Wang
HW |
(2025) "Structural
basis of endo-siRNA processing by Drosophila Dicer-2
and Loqs-PD." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf102.
|
Dmdcr-2-loqspd-slm2 in initial binding state . SNAP output
|
|
8yih
|
structural protein-RNA |
cryo-EM (4.08 Å) |
Cao N, Wang J, Deng T, Fan B, Su S, Ma J, Wang
HW |
(2025) "Structural
basis of endo-siRNA processing by Drosophila Dicer-2
and Loqs-PD." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf102.
|
Dmdcr-2-loqspd-slm1 in pre-dicing state . SNAP output
|
|
8yii
|
structural protein-RNA |
cryo-EM (3.42 Å) |
Cao N, Wang J, Deng T, Fan B, Su S, Ma J, Wang
HW |
(2025) "Structural
basis of endo-siRNA processing by Drosophila Dicer-2
and Loqs-PD." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf102.
|
Dmdcr-2-loqspd-slm2 in dicing state . SNAP output
|
|
8yld
|
ribosome |
cryo-EM (3.9 Å) |
Cheng J, Wu C, Li J, Yang Q, Zhao M, Zhang X |
(2025) "Capturing
eukaryotic ribosome dynamics in situ at high
resolution." Nat.Struct.Mol.Biol.,
32, 698-708. doi: 10.1038/s41594-024-01454-9.
|
State 4a (s4a) of yeast 80s ribosome bound to 2 trnas
and open eef3 and eef2 during translocation . SNAP output
|
|
8ylr
|
ribosome |
cryo-EM (3.9 Å) |
Cheng J, Wu C, Li J, Yang Q, Zhao M, Zhang X |
(2025) "Capturing
eukaryotic ribosome dynamics in situ at high
resolution." Nat.Struct.Mol.Biol.,
32, 698-708. doi: 10.1038/s41594-024-01454-9.
|
State 6 (s6) of yeast 80s ribosome bound to 2 trnas and
eef2 and eef3 during tranlocation . SNAP output
|
|
8yp6
|
ribosome |
cryo-EM (4.7 Å) |
Banerjee A, Srinivasan K, Sengupta J |
"Cryo-EM map of 30S ribosomal subunit in complex with
MetAP1c of Mycobacterium smegmatis." |
cryo-EM map of 30s ribosomal subunit in complex with
metap1c of mycobacterium smegmatis . SNAP output
|
|
8yuo
|
ribosome |
cryo-EM (2.25 Å) |
Miyauchi K, Kimura S, Akiyama N, Inoue K, Ishiguro K,
Vu TS, Srisuknimit V, Koyama K, Hayashi G, Soma A, Nagao
A, Shirouzu M, Okamoto A, Waldor MK, Suzuki T |
(2025) "A tRNA
modification with aminovaleramide facilitates AUA
decoding in protein synthesis."
Nat.Chem.Biol., 21, 522-531.
doi: 10.1038/s41589-024-01726-x.
|
E. coli 70s ribosome complexed with p. putida trnaile2
at the a-site and p-site . SNAP output
|
|
8yup
|
ribosome |
cryo-EM (2.39 Å) |
Miyauchi K, Kimura S, Akiyama N, Inoue K, Ishiguro K,
Vu TS, Srisuknimit V, Koyama K, Hayashi G, Soma A, Nagao
A, Shirouzu M, Okamoto A, Waldor MK, Suzuki T |
(2025) "A tRNA
modification with aminovaleramide facilitates AUA
decoding in protein synthesis."
Nat.Chem.Biol., 21, 522-531.
doi: 10.1038/s41589-024-01726-x.
|
E. coli 70s ribosome complexed with p. putida trnaile2
and a4 mrna . SNAP
output
|
|
8yuq
|
ribosome |
cryo-EM (2.41 Å) |
Miyauchi K, Kimura S, Akiyama N, Inoue K, Ishiguro K,
Vu TS, Srisuknimit V, Koyama K, Hayashi G, Soma A, Nagao
A, Shirouzu M, Okamoto A, Waldor MK, Suzuki T |
(2025) "A tRNA
modification with aminovaleramide facilitates AUA
decoding in protein synthesis."
Nat.Chem.Biol., 21, 522-531.
doi: 10.1038/s41589-024-01726-x.
|
E. coli 70s ribosome complexed with p. putida trnaile2
and da4 mrna . SNAP
output
|
|
8yur
|
ribosome |
cryo-EM (2.47 Å) |
Miyauchi K, Kimura S, Akiyama N, Inoue K, Ishiguro K,
Vu TS, Srisuknimit V, Koyama K, Hayashi G, Soma A, Nagao
A, Shirouzu M, Okamoto A, Waldor MK, Suzuki T |
(2025) "A tRNA
modification with aminovaleramide facilitates AUA
decoding in protein synthesis."
Nat.Chem.Biol., 21, 522-531.
doi: 10.1038/s41589-024-01726-x.
|
E. coli 70s ribosome complexed with p. putida trnaile2
and am4 mrna . SNAP
output
|
|
8yus
|
ribosome |
cryo-EM (2.43 Å) |
Miyauchi K, Kimura S, Akiyama N, Inoue K, Ishiguro K,
Vu TS, Srisuknimit V, Koyama K, Hayashi G, Soma A, Nagao
A, Shirouzu M, Okamoto A, Waldor MK, Suzuki T |
(2025) "A tRNA
modification with aminovaleramide facilitates AUA
decoding in protein synthesis."
Nat.Chem.Biol., 21, 522-531.
doi: 10.1038/s41589-024-01726-x.
|
E. coli 70s ribosome complexed with p.putida trnaile2
and a(f)4 mrna . SNAP
output
|
|
8z1f
|
RNA binding protein |
cryo-EM (4.3 Å) |
Xue C, Tian J, Chen Y, Liu Z |
(2024) "Structural
insights into human ELAC2 as a tRNA 3' processing
enzyme." Nucleic Acids Res.,
52, 13434-13446. doi: 10.1093/nar/gkae1014.
|
cryo-EM structure of human elac2-trna . SNAP output
|
|
8z1g
|
RNA binding protein |
cryo-EM (3.7 Å) |
Xue C, Tian J, Chen Y, Liu Z |
(2024) "Structural
insights into human ELAC2 as a tRNA 3' processing
enzyme." Nucleic Acids Res.,
52, 13434-13446. doi: 10.1093/nar/gkae1014.
|
cryo-EM structure of human elac2-pre-trna . SNAP output
|
|
8z1p
|
ligase-RNA |
X-ray (2.83 Å) |
Chen B, Yi F, Luo Z, Lu F, Liu H, Luo S, Gu Q, Zhou
H |
(2024) "The
mechanism of discriminative aminoacylation by
isoleucyl-tRNA synthetase based on wobble nucleotide
recognition." Nat Commun,
15, 10817. doi: 10.1038/s41467-024-55183-0.
|
Crystal structure of saccharomyces cerevisiae
isoleucyl-trna synthetase in complex with a mimic
trna(met) and isoleucine . SNAP output
|
|
8z3k
|
immune system |
cryo-EM (3.19 Å) |
Li Y, Li Z, Yan P, Hua C, Kong J, Wu W, Cui Y, Duan
Y, Li S, Li G, Ji S, Chen Y, Zhao Y, Yang P, Hu C, Lu M,
Chen M, Xiao Y |
(2025) "Antiviral
signaling of a type III CRISPR-associated
deaminase." Science, 387,
eadr0393. doi: 10.1126/science.adr0393.
|
The structure of type iii crispr-associated deaminase
in complex 2ca6-2atp . SNAP output
|
|
8z3p
|
immune system |
cryo-EM (3.4 Å) |
Li Y, Li Z, Yan P, Hua C, Kong J, Wu W, Cui Y, Duan
Y, Li S, Li G, Ji S, Chen Y, Zhao Y, Yang P, Hu C, Lu M,
Chen M, Xiao Y |
(2025) "Antiviral
signaling of a type III CRISPR-associated
deaminase." Science, 387,
eadr0393. doi: 10.1126/science.adr0393.
|
The structure of type iii crispr-associated deaminase
in complex ca6 and atp, fully activated . SNAP output
|
|
8z4j
|
antiviral protein |
cryo-EM (2.97 Å) |
Yang J, Li X, He Q, Wang X, Tang J, Wang T, Zhang Y,
Yu F, Zhang S, Liu Z, Zhang L, Liao F, Yin H, Zhao H,
Deng Z, Zhang H |
(2024) "Structural
basis for the activity of the type VII CRISPR-Cas
system." Nature, 633,
465-472. doi: 10.1038/s41586-024-07815-0.
|
cryo-EM structure of ctr-bound type vii crispr-cas
complex at substrate-engaged state ii . SNAP output
|
|
8z4l
|
antiviral protein |
cryo-EM (2.85 Å) |
Yang J, Li X, He Q, Wang X, Tang J, Wang T, Zhang Y,
Yu F, Zhang S, Liu Z, Zhang L, Liao F, Yin H, Zhao H,
Deng Z, Zhang H |
(2024) "Structural
basis for the activity of the type VII CRISPR-Cas
system." Nature, 633,
465-472. doi: 10.1038/s41586-024-07815-0.
|
cryo-EM structure of ctr-bound type vii crispr-cas
complex at substrate-engaged state i . SNAP output
|
|
8z70
|
ribosome |
cryo-EM (3.2 Å) |
Cheng J, Wu C, Li J, Yang Q, Zhao M, Zhang X |
(2025) "Capturing
eukaryotic ribosome dynamics in situ at high
resolution." Nat.Struct.Mol.Biol.,
32, 698-708. doi: 10.1038/s41594-024-01454-9.
|
State 1 (s1) of yeast 80s ribosome bound to 2 trnas
during mrna decoding . SNAP output
|
|
8z71
|
ribosome |
cryo-EM (3.6 Å) |
Cheng J, Wu C, Li J, Yang Q, Zhao M, Zhang X |
(2025) "Capturing
eukaryotic ribosome dynamics in situ at high
resolution." Nat.Struct.Mol.Biol.,
32, 698-708. doi: 10.1038/s41594-024-01454-9.
|
State 1a (s1a) of yeast 80s ribosome bound to open eef3
and 2 trnas and eef1a during mrna decoding . SNAP output
|
|
8z85
|
transcription |
cryo-EM (2.3 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in
transcription pre-initiation conformation 1 . SNAP output
|
|
8z8j
|
transcription |
cryo-EM (3.16 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in
transcription pre-initiation conformation 2 . SNAP output
|
|
8z8n
|
transcription |
cryo-EM (2.79 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in
transcription pre-initiation conformation 3 . SNAP output
|
|
8z8x
|
transcription |
cryo-EM (3.06 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in a
transcription initiation conformation . SNAP output
|
|
8z90
|
transcription |
cryo-EM (2.87 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in
transcription initiation conformation 2 . SNAP output
|
|
8z97
|
transcription |
cryo-EM (2.65 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in a
transcription elongation conformation . SNAP output
|
|
8z98
|
transcription |
cryo-EM (2.52 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in a
transcription reception conformation . SNAP output
|
|
8z99
|
antiviral protein |
cryo-EM (3.2 Å) |
Yang J, Li X, He Q, Wang X, Tang J, Wang T, Zhang Y,
Yu F, Zhang S, Liu Z, Zhang L, Liao F, Yin H, Zhao H,
Deng Z, Zhang H |
(2024) "Structural
basis for the activity of the type VII CRISPR-Cas
system." Nature, 633,
465-472. doi: 10.1038/s41586-024-07815-0.
|
cryo-EM structure of ntr-bound type vii crispr-cas
complex at substrate-engaged state +i . SNAP output
|
|
8z9c
|
antiviral protein |
cryo-EM (3.01 Å) |
Yang J, Li X, He Q, Wang X, Tang J, Wang T, Zhang Y,
Yu F, Zhang S, Liu Z, Zhang L, Liao F, Yin H, Zhao H,
Deng Z, Zhang H |
(2024) "Structural
basis for the activity of the type VII CRISPR-Cas
system." Nature, 633,
465-472. doi: 10.1038/s41586-024-07815-0.
|
cryo-EM structure of ntr-bound type vii crispr-cas
complex at substrate-engaged state i . SNAP output
|
|
8z9e
|
antiviral protein |
cryo-EM (3.13 Å) |
Yang J, Li X, He Q, Wang X, Tang J, Wang T, Zhang Y,
Yu F, Zhang S, Liu Z, Zhang L, Liao F, Yin H, Zhao H,
Deng Z, Zhang H |
(2024) "Structural
basis for the activity of the type VII CRISPR-Cas
system." Nature, 633,
465-472. doi: 10.1038/s41586-024-07815-0.
|
cryo-EM structure of ntr-bound type vii crispr-cas
complex at substrate-engaged state ii . SNAP output
|
|
8z9h
|
transcription |
cryo-EM (2.7 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in a
transcription elongation-reception conformation .
SNAP output
|
|
8z9q
|
transcription |
cryo-EM (2.33 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in a
replication reception conformation . SNAP output
|
|
8z9r
|
transcription |
cryo-EM (2.58 Å) |
Xue L, Chang T, Li Z, Wang C, Zhao H, Li M, Tang P,
Wen X, Yu M, Wu J, Bao X, Wang X, Gong P, He J, Chen X,
Xiong X |
(2024) "Cryo-EM
structures of Thogoto virus polymerase reveal unique
RNA transcription and replication mechanisms among
orthomyxoviruses." Nat Commun,
15, 4620. doi: 10.1038/s41467-024-48848-3.
|
cryo-EM structure of thogoto virus polymerase in a
replication elongation-reception conformation .
SNAP output
|
|
8zdb
|
ribosome |
cryo-EM (3.6 Å) |
Huang Z, Diehl FF, Wang M, Li Y, Song A, Chen FX,
Rosa-Mercado NA, Beckmann R, Green R, Cheng J |
(2025) "RIOK3
mediates the degradation of 40S ribosomes."
Mol.Cell, 85, 802. doi:
10.1016/j.molcel.2025.01.013.
|
cryo-EM structure of the human ubiquitylated 40s
ribosome with riok3 . SNAP output
|
|
8zdc
|
ribosome |
cryo-EM (3.8 Å) |
Huang Z, Diehl FF, Wang M, Li Y, Song A, Chen FX,
Rosa-Mercado NA, Beckmann R, Green R, Cheng J |
(2025) "RIOK3
mediates the degradation of 40S ribosomes."
Mol.Cell, 85, 802. doi:
10.1016/j.molcel.2025.01.013.
|
cryo-EM structure of the human ubiquitylated pre-40s
ribosome with riok3 . SNAP output
|
|
8zdd
|
ribosome |
cryo-EM (3.7 Å) |
Huang Z, Diehl FF, Wang M, Li Y, Song A, Chen FX,
Rosa-Mercado NA, Beckmann R, Green R, Cheng J |
(2025) "RIOK3
mediates the degradation of 40S ribosomes."
Mol.Cell, 85, 802. doi:
10.1016/j.molcel.2025.01.013.
|
cryo-EM structure of the human ubiquitylated pre-40s
ribosome with riok3 (without nob1) . SNAP output
|
|
8zdy
|
antiviral protein |
cryo-EM (3.6 Å) |
Li X, Liu Y, Han J, Zhang L, Liu Z, Wang L, Zhang S,
Zhang Q, Fu P, Yin H, Zhu H, Zhang H |
(2024) "Structural
basis for the type I-F Cas8-HNH system." Embo
J., 43, 4656-4667. doi: 10.1038/s44318-024-00229-8.
|
cryo-EM structure of cas8-hnh system at target free
state . SNAP output
|
|
8zej
|
ribosome |
cryo-EM (2.69 Å) |
Sriramoju MK, Ko TP, Draczkowski P, Hsu STD |
"Structure of E.coli ribosome in complex with an
engineered arrest peptide." |
Structure of e.coli ribosome in complex with an
engineered arrest peptide . SNAP output
|
|
8zfi
|
ribosome |
cryo-EM (2.9 Å) |
Sriramoju MK, Ko TP, Draczkowski P, Hsu STD |
"Structure of E.coli ribosome in complex with an
engineered arrest peptide and trigger factor." |
Structure of e.coli ribosome in complex with an
engineered arrest peptide and trigger factor . SNAP output
|
|
8zgr
|
ribosome |
cryo-EM (2.7 Å) |
Wu M, Wan X, Zhou H, Yuan S |
"Flexibilities and conservations in the structural
basis of viral -1 programmed ribosomal
frameshifting." |
80s ribosome with a-a trna and mrna of wnv . SNAP output
|
|
8zgy
|
ribosome |
cryo-EM (2.8 Å) |
Wu M, Wan X, Zhou H, Yuan S |
"Flexibilities and conservations in the structural
basis of viral -1 programmed ribosomal
frameshifting." |
80s ribosome with p-e trna and mrna of wnv . SNAP output
|
|
8zh3
|
ribosome |
cryo-EM (2.7 Å) |
Wu M, Wan X, Zhou H, Yuan S |
"Flexibilities and conservations in the structural
basis of viral -1 programmed ribosomal
frameshifting." |
80s ribosome with a-p-p-e trna and mrna of wnv .
SNAP output
|
|
8zhb
|
ribosome |
cryo-EM (2.6 Å) |
Wu M, Wan X, Zhou H, Yuan S |
"Flexibilities and conservations in the structural
basis of viral -1 programmed ribosomal
frameshifting." |
80s ribosome with a-a p-e trna and mrna of wnv .
SNAP output
|
|
8zhc
|
ribosome |
cryo-EM (2.3 Å) |
Wu M, Wan X, Zhou H, Yuan S |
"Flexibilities and conservations in the structural
basis of viral -1 programmed ribosomal
frameshifting." |
Pre-frameshift complex of yeast 80s ribosome with erf1
and mrna of wnv . SNAP
output
|
|
8zlu
|
immune system |
cryo-EM (2.47 Å) |
Liu Y, Wang L, Zhang Q, Fu P, Zhang L, Yu Y, Zhang H,
Zhu H |
(2025) "Structural
basis for RNA-guided DNA degradation by
Cas5-HNH/Cascade complex." Nat Commun,
16, 1335. doi: 10.1038/s41467-024-55716-7.
|
cryo-EM strcuture of cas5-hnh cascade,conf1 . SNAP output
|
|
8zm3
|
immune system-RNA |
cryo-EM (3.1 Å) |
Liu Y, Wang L, Zhang Q, Fu P, Zhang L, Yu Y, Zhang H,
Zhu H |
(2025) "Structural
basis for RNA-guided DNA degradation by
Cas5-HNH/Cascade complex." Nat Commun,
16, 1335. doi: 10.1038/s41467-024-55716-7.
|
cryo-EM strcuture of cas5-hnh cascade,apo-conf2 .
SNAP output
|
|
8zmi
|
ligase-RNA |
cryo-EM (3.49 Å) |
Yang W, Yi R, Yao J, Gao Y, Li S, Gong Q, Zhang
K |
(2025) "Structural
insights into dynamics of the BMV TLS
aminoacylation." Nat Commun,
16, 1276. doi: 10.1038/s41467-025-56612-4.
|
cryo-EM structure of bmv tls-tyrrs-atp(pre-1a state) .
SNAP output
|
|
8zmj
|
ligase-RNA |
cryo-EM (3.73 Å) |
Yang W, Yi R, Yao J, Gao Y, Li S, Gong Q, Zhang
K |
(2025) "Structural
insights into dynamics of the BMV TLS
aminoacylation." Nat Commun,
16, 1276. doi: 10.1038/s41467-025-56612-4.
|
cryo-EM structure of bmv tls-tyrrs-ymp(post-1a state) .
SNAP output
|
|
8zmk
|
ligase-RNA |
cryo-EM (3.85 Å) |
Yang W, Yi R, Yao J, Gao Y, Li S, Gong Q, Zhang
K |
(2025) "Structural
insights into dynamics of the BMV TLS
aminoacylation." Nat Commun,
16, 1276. doi: 10.1038/s41467-025-56612-4.
|
cryo-EM structure of bmv tls-tyrrs (catalysis state) .
SNAP output
|
|
8zol
|
immune system-RNA |
cryo-EM (2.55 Å) |
Liu Y, Wang L, Zhang Q, Fu P, Zhang L, Yu Y, Zhang H,
Zhu H |
(2025) "Structural
basis for RNA-guided DNA degradation by
Cas5-HNH/Cascade complex." Nat Commun,
16, 1335. doi: 10.1038/s41467-024-55716-7.
|
cryo-EM strcuture of cas5-hnh cascade,conf3 . SNAP output
|
|
8zq9
|
antiviral protein |
cryo-EM (2.87 Å) |
Li X, Zhang H, Liu Z |
"Cryo-EM structure of the Cas9d-sgRNA complex." |
cryo-EM structure of the cas9d-sgrna complex . SNAP output
|
|
8zqb
|
RNA binding protein-RNA |
cryo-EM (3.65 Å) |
Zhang X |
"Cryo-EM structure of Cas12X with crRNA." |
cryo-EM structure of cas12x with crrna . SNAP output
|
|
8ztu
|
ribosome |
cryo-EM (2.9 Å) |
Ando Y, Kobo A, Niwa T, Yamakawa A, Konoma S,
Kobayashi Y, Nureki O, Taguchi H, Itoh Y, Chadani Y |
(2025) "A
mini-hairpin shaped nascent peptide blocks translation
termination by a distinct mechanism." Nat
Commun, 16, 2323. doi: 10.1038/s41467-025-57659-z.
|
70s ribosome arrested by pepnl . SNAP output
|
|
8ztv
|
ribosome |
cryo-EM (2.9 Å) |
Ando Y, Kobo A, Niwa T, Yamakawa A, Konoma S,
Kobayashi Y, Nureki O, Taguchi H, Itoh Y, Chadani Y |
(2025) "A
mini-hairpin shaped nascent peptide blocks translation
termination by a distinct mechanism." Nat
Commun, 16, 2323. doi: 10.1038/s41467-025-57659-z.
|
70s ribosome arrested by pepnl with rf2 . SNAP output
|
|
8zty
|
RNA binding protein-RNA |
cryo-EM (2.85 Å) |
Hayes VM, Zhang JT, Katz MA, Li Y, Kocsis B, Brinkley
DM, Jia N, Meeske AJ |
(2025) "RNA-mediated
CRISPR-Cas13 inhibition through crRNA structural
mimicry." Science, 388,
387-391. doi: 10.1126/science.adr3656.
|
cryo-EM structure of the cas13a-racrvia1 complex .
SNAP output
|
|
8zwj
|
protein fibril |
cryo-EM (3.1 Å) |
Tao YQ, Liu C, Li D |
"Polyadenylic acid bound alpha-synuclein fibril
Polymorph 1." |
Polyadenylic acid bound alpha-synuclein fibril
polymorph 1 . SNAP
output
|
|
8zwk
|
protein fibril |
cryo-EM (3.4 Å) |
Tao YQ, Liu C, Li D |
"Polyadenylic acid bound alpha-synuclein fibril
Polymorph 2." |
Polyadenylic acid bound alpha-synuclein fibril
polymorph 2 . SNAP
output
|
|
8zyc
|
toxin |
cryo-EM (2.99 Å) |
Feng Z, Yashiro Y, Tomita K |
(2025) "Mechanism
of activation of contact-dependent growth inhibition
tRNase toxin by the amino acid biogenesis factor CysK
in the bacterial competition system." Nucleic
Acids Res., 53. doi: 10.1093/nar/gkae735.
|
cryo-EM structure of uropathogenic escherichia coli
cysk:cdia:trna complex a . SNAP output
|
|
8zyd
|
toxin |
cryo-EM (3.04 Å) |
Feng Z, Yashiro Y, Tomita K |
(2025) "Mechanism
of activation of contact-dependent growth inhibition
tRNase toxin by the amino acid biogenesis factor CysK
in the bacterial competition system." Nucleic
Acids Res., 53. doi: 10.1093/nar/gkae735.
|
cryo-EM structure of uropathogenic escherichia coli
cysk:cdia:trna complex b . SNAP output
|
|
9ash
|
RNA binding protein-RNA |
cryo-EM (2.58 Å) |
Goswami HN, Ahmadizadeh F, Wang B, Addo-Yobo D, Zhao
Y, Whittington AC, He H, Terns MP, Li H |
(2024) "Molecular
basis for cA6 synthesis by a type III-A CRISPR-Cas
enzyme and its conversion to cA4 production."
Nucleic Acids Res., 52,
10619-10629. doi: 10.1093/nar/gkae603.
|
cryo-EM structure of the active lactococcus lactis csm
bound to target in post-cleavage stage . SNAP output
|
|
9asi
|
RNA binding protein-RNA |
cryo-EM (2.79 Å) |
Goswami HN, Ahmadizadeh F, Wang B, Addo-Yobo D, Zhao
Y, Whittington AC, He H, Terns MP, Li H |
(2024) "Molecular
basis for cA6 synthesis by a type III-A CRISPR-Cas
enzyme and its conversion to cA4 production."
Nucleic Acids Res., 52,
10619-10629. doi: 10.1093/nar/gkae603.
|
cryo-EM structure of the active lactococcus lactis csm
bound to target in pre-cleavage stage . SNAP output
|
|
9asm
|
RNA binding protein-RNA |
cryo-EM (2.8 Å) |
Garg A, Shang R, Cvetanovic T, Lai EC, Joshua-Tor
L |
(2024) "The
structural landscape of Microprocessor-mediated
processing of pri-let-7 miRNAs." Mol.Cell,
84, 4175-4190.e6. doi: 10.1016/j.molcel.2024.09.008.
|
Human drosha and dgcr8 in complex with pri-let-7f1 .
SNAP output
|
|
9asn
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Garg A, Shang R, Cvetanovic T, Lai EC, Joshua-Tor
L |
(2024) "The
structural landscape of Microprocessor-mediated
processing of pri-let-7 miRNAs." Mol.Cell,
84, 4175-4190.e6. doi: 10.1016/j.molcel.2024.09.008.
|
Human drosha and dgcr8 in complex with pri-mir-98 .
SNAP output
|
|
9aso
|
RNA binding protein-RNA |
cryo-EM (2.9 Å) |
Garg A, Shang R, Cvetanovic T, Lai EC, Joshua-Tor
L |
(2024) "The
structural landscape of Microprocessor-mediated
processing of pri-let-7 miRNAs." Mol.Cell,
84, 4175-4190.e6. doi: 10.1016/j.molcel.2024.09.008.
|
Human drosha and dgcr8 in complex with pri-let-7a2 .
SNAP output
|
|
9asp
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Garg A, Shang R, Cvetanovic T, Lai EC, Joshua-Tor
L |
(2024) "The
structural landscape of Microprocessor-mediated
processing of pri-let-7 miRNAs." Mol.Cell,
84, 4175-4190.e6. doi: 10.1016/j.molcel.2024.09.008.
|
Human drosha and dgcr8 in complex with pri-let-7a1 .
SNAP output
|
|
9asq
|
RNA binding protein-RNA |
cryo-EM (3.0 Å) |
Garg A, Shang R, Cvetanovic T, Lai EC, Joshua-Tor
L |
(2024) "The
structural landscape of Microprocessor-mediated
processing of pri-let-7 miRNAs." Mol.Cell,
84, 4175-4190.e6. doi: 10.1016/j.molcel.2024.09.008.
|
Human drosha, dgcr8 and srsf3 in complex with
pri-let-7f1 . SNAP
output
|
|
9aur
|
RNA |
X-ray (1.57 Å) |
Radakovic A, Lewicka A, Todisco M, Aitken HRM, Weiss
Z, Kim S, Bannan A, Piccirilli JA, Szostak JW |
(2024) "A
potential role for RNA aminoacylation prior to its role
in peptide synthesis."
Proc.Natl.Acad.Sci.USA, 121,
e2410206121. doi: 10.1073/pnas.2410206121.
|
Crystal structure of loop-closed a21 2'-ome dumbbell
RNA bridged by glycine . SNAP output
|
|
9aus
|
RNA |
X-ray (2.07 Å) |
Radakovic A, Lewicka A, Todisco M, Aitken HRM, Weiss
Z, Kim S, Bannan A, Piccirilli JA, Szostak JW |
(2024) "A
potential role for RNA aminoacylation prior to its role
in peptide synthesis."
Proc.Natl.Acad.Sci.USA, 121,
e2410206121. doi: 10.1073/pnas.2410206121.
|
Crystal structure of loop-closed dumbbell RNA bridged
by glycine . SNAP
output
|
|
9avr
|
RNA binding protein |
X-ray (1.91 Å) |
Naineni SK, Bhatt G, Jiramongkolsiri E, Robert F,
Cencic R, Huang S, Nagar B, Pelletier J |
(2024) "Protein-RNA
interactions mediated by silvestrol-insight into a
unique molecular clamp." Nucleic Acids
Res., 52, 12701-12711. doi:
10.1093/nar/gkae824.
|
Human eif4a-1 in complex with amp-pnp, RNA, and the
inhibitor silvestrol . SNAP output
|
|
9ax7
|
ribosome |
cryo-EM (2.63 Å) |
Mattingly JM, Nguyen HA, Roy B, Fredrick K, Dunham
CM |
(2024) "Structural
analysis of noncanonical translation initiation
complexes." J.Biol.Chem.,
300, 107743. doi: 10.1016/j.jbc.2024.107743.
|
70s initiation complex (trna-fmet m1 + cug start codon)
. SNAP output
|
|
9ax8
|
ribosome |
cryo-EM (2.6 Å) |
Mattingly JM, Nguyen HA, Roy B, Fredrick K, Dunham
CM |
(2024) "Structural
analysis of noncanonical translation initiation
complexes." J.Biol.Chem.,
300, 107743. doi: 10.1016/j.jbc.2024.107743.
|
70s initiation complex (trna-fmet m1, initiation factor
2 + cug start codon) . SNAP output
|
|
9axt
|
ribosome |
cryo-EM (2.4 Å) |
Gemin O, Gluc M, Rosa H, Purdy M, Niemann M, Peskova
Y, Mattei S, Jomaa A |
(2024) "Ribosomes
hibernate on mitochondria during cellular stress."
Nat Commun, 15, 8666. doi:
10.1038/s41467-024-52911-4.
|
Non-translating s. pombe ribosome . SNAP output
|
|
9axu
|
ribosome |
cryo-EM (1.94 Å) |
Gemin O, Gluc M, Rosa H, Purdy M, Niemann M, Peskova
Y, Mattei S, Jomaa A |
(2024) "Ribosomes
hibernate on mitochondria during cellular stress."
Nat Commun, 15, 8666. doi:
10.1038/s41467-024-52911-4.
|
Non-translating s. pombe ribosome large subunit .
SNAP output
|
|
9axv
|
ribosome |
cryo-EM (2.4 Å) |
Gemin O, Gluc M, Rosa H, Purdy M, Niemann M, Peskova
Y, Mattei S, Jomaa A |
(2024) "Ribosomes
hibernate on mitochondria during cellular stress."
Nat Commun, 15, 8666. doi:
10.1038/s41467-024-52911-4.
|
Translating s. pombe ribosome . SNAP output
|
|
9azm
|
ribosome |
cryo-EM (2.68 Å) |
Wei Z, Yong Z |
"In situ human ribosome (Focused on 40S with SERBP1
CTD)." |
In situ human ribosome (focused on 40s with serbp1 ctd)
. SNAP output
|
|
9b00
|
ribosome |
X-ray (2.8 Å) |
Batool Z, Pavlova JA, Paranjpe MN, Tereshchenkov AG,
Lukianov DA, Osterman IA, Bogdanov AA, Sumbatyan NV,
Polikanov YS |
(2024) "Berberine
analog of chloramphenicol exhibits a distinct mode of
action and unveils ribosome plasticity."
Structure, 32, 1429. doi:
10.1016/j.str.2024.06.013.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with berberine analog of
chloramphenicol cam-ber, mrna, deacylated a- and e-site
trnaphe, and deacylated p-site trnamet at 2.80a
resolution . SNAP
output
|
|
9b1w
|
ribosome |
cryo-EM (3.26 Å) |
Chen Y, Young ID, Fraser JS, Javid B |
"Ribosomal RNA methylation by GidB is a capacitor for
discrimination of mischarged tRNA." |
Hws19 strain wt mycobacterial ribosome . SNAP output
|
|
9b1x
|
ribosome |
cryo-EM (3.07 Å) |
Chen Y, Young ID, Fraser JS, Javid B |
"Ribosomal RNA methylation by GidB is a capacitor for
discrimination of mischarged tRNA." |
Hws19 strain gidb mutant mycobacterial ribosome .
SNAP output
|
|
9b1y
|
ribosome |
cryo-EM (2.47 Å) |
Chen Y, Young ID, Fraser JS, Javid B |
"Ribosomal RNA methylation by GidB is a capacitor for
discrimination of mischarged tRNA." |
Wt strain wt mycobacterial ribosome . SNAP output
|
|
9b24
|
ribosome |
cryo-EM (2.47 Å) |
Chen Y, Young ID, Fraser JS, Javid B |
"Ribosomal RNA methylation by GidB is a capacitor for
discrimination of mischarged tRNA." |
Wt strain gidb mutant mycobacterial ribosome . SNAP output
|
|
9b2k
|
hydrolase |
cryo-EM (3.67 Å) |
Korolev S, Gagnon K |
"SpCas9 with dual-guide RNA and target DNA." |
Spcas9 with dual-guide RNA in open conformation .
SNAP output
|
|
9b83
|
hydrolase-RNA |
cryo-EM (3.01 Å) |
Deng X, Sun L, Zhang M, Basavaraj R, Wang J, Weng YL,
Gao Y |
(2025) "Biochemical
profiling and structural basis of ADAR1-mediated RNA
editing." Mol.Cell, 85,
1381-1394.e6. doi: 10.1016/j.molcel.2025.02.017.
|
cryo-EM structure of human adar1 in complex with dsrna
derived from human gli1 gene . SNAP output
|
|
9b84
|
hydrolase-RNA |
cryo-EM (3.2 Å) |
Deng X, Sun L, Zhang M, Basavaraj R, Wang J, Weng YL,
Gao Y |
(2025) "Biochemical
profiling and structural basis of ADAR1-mediated RNA
editing." Mol.Cell, 85,
1381-1394.e6. doi: 10.1016/j.molcel.2025.02.017.
|
cryo-EM structure of human adar1 in complex with dsrna
derived from ht2c gene . SNAP output
|
|
9b89
|
hydrolase-RNA |
cryo-EM (3.87 Å) |
Deng X, Sun L, Zhang M, Basavaraj R, Wang J, Weng YL,
Gao Y |
(2025) "Biochemical
profiling and structural basis of ADAR1-mediated RNA
editing." Mol.Cell, 85,
1381-1394.e6. doi: 10.1016/j.molcel.2025.02.017.
|
cryo-EM structure of human adar1 in complex with dsrna
derived from ht2c gene in the pre-editing state .
SNAP output
|
|
9bdl
|
ribosome |
cryo-EM (2.8 Å) |
Loveland AB, Koh CS, Ganesan R, Jacobson A,
Korostelev AA |
(2024) "Structural
mechanism of angiogenin activation by the
ribosome." Nature, 630,
769-776. doi: 10.1038/s41586-024-07508-8.
|
80s ribosome with angiogenin . SNAP output
|
|
9bdn
|
ribosome |
cryo-EM (3.1 Å) |
Loveland AB, Koh CS, Ganesan R, Jacobson A,
Korostelev AA |
(2024) "Structural
mechanism of angiogenin activation by the
ribosome." Nature, 630,
769-776. doi: 10.1038/s41586-024-07508-8.
|
80s ribosome with angiogenin and trnaala . SNAP output
|
|
9bdp
|
ribosome |
cryo-EM (3.7 Å) |
Loveland AB, Koh CS, Ganesan R, Jacobson A,
Korostelev AA |
(2024) "Structural
mechanism of angiogenin activation by the
ribosome." Nature, 630,
769-776. doi: 10.1038/s41586-024-07508-8.
|
80s ribosome bound with angiogenin and complex of eef1a
and ala-trnaala . SNAP
output
|
|
9bh5
|
ribosome |
cryo-EM (2.63 Å) |
Sehgal E, Wohlenberg C, Soukup EM, Viscardi MJ,
Serrao VHB, Arribere JA |
(2024) "High-resolution
reconstruction of a C. elegans ribosome sheds light on
evolutionary dynamics and tissue specificity."
Rna, 30, 1513-1528. doi:
10.1261/rna.080103.124.
|
High-resolution c. elegans 80s ribosome structure -
class 1 . SNAP
output
|
|
9bih
|
viral protein |
cryo-EM (3.24 Å) |
Wright ZM, Butay KJ, Krahn JM, Wilson IM, Gabel SA,
DeRose EF, Hissein IS, Williams JG, Borgnia MJ, Frazier
MN, Mueller GA, Stanley RE |
(2025) "Spontaneous
base flipping helps drive Nsp15's preferences in double
stranded RNA substrates." Nat Commun,
16, 391. doi: 10.1038/s41467-024-55682-0.
|
Sars-cov-2 endoribonuclease nsp15 bound to dsrna with 1
nucleotide bulge . SNAP
output
|
|
9bkd
|
antitumor protein |
cryo-EM (2.6 Å) |
Brito Querido J, Sokabe M, Diaz-Lopez I, Gordiyenko
Y, Zuber P, Du Y, Albacete-Albacete L, Ramakrishnan V,
Fraser CS |
(2024) "Human
tumor suppressor protein Pdcd4 binds at the mRNA entry
channel in the 40S small ribosomal subunit."
Nat Commun, 15, 6633. doi:
10.1038/s41467-024-50672-8.
|
The structure of human pdcd4 bound to the 40s small
ribosomal subunit . SNAP
output
|
|
9blf
|
viral protein-RNA-inhibitor |
cryo-EM (3.31 Å) |
Anderson TK, Kirchdoerfer RN |
"Structure of the SARS-CoV-2 core-RTC bound to RNA,
araCMP, and araCTP." |
Sars-cov-2 core polymerase complex inhibited by aractp
. SNAP output
|
|
9bln
|
antitumor protein |
cryo-EM (3.9 Å) |
Brito Querido J, Sokabe M, Diaz-Lopez I, Gordiyenko
Y, Zuber P, Du Y, Albacete-Albacete L, Ramakrishnan V,
Fraser CS |
(2024) "Human
tumor suppressor protein Pdcd4 binds at the mRNA entry
channel in the 40S small ribosomal subunit."
Nat Commun, 15, 6633. doi:
10.1038/s41467-024-50672-8.
|
The structure of human pdcd4 bound to the
40s-eif4a-eif3-eif1 complex . SNAP output
|
|
9bs0
|
ribosome |
cryo-EM (3.3 Å) |
Arpin D, Palacios A, Basu K, Ortega J |
(2025) "The
binding of RbgA to a critical 50S assembly intermediate
facilitates YphC function in bacterial ribosomal
assembly." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkae1197.
|
Yphc-treated 45syphc particle. class 5 . SNAP output
|
|
9bsl
|
ribosome |
cryo-EM (3.1 Å) |
Arpin D, Palacios A, Basu K, Ortega J |
(2025) "The
binding of RbgA to a critical 50S assembly intermediate
facilitates YphC function in bacterial ribosomal
assembly." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkae1197.
|
45srbga particle in complex with rbga and yphc. class a
. SNAP output
|
|
9bss
|
ribosome |
cryo-EM (3.1 Å) |
Arpin D, Palacios A, Basu K, Ortega J |
(2025) "The
binding of RbgA to a critical 50S assembly intermediate
facilitates YphC function in bacterial ribosomal
assembly." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkae1197.
|
45srbga particle in complex with rbga and yphc. class b
. SNAP output
|
|
9bup
|
ribosome |
cryo-EM (2.7 Å) |
Anton L, Cheng W, Haile M, Cobb DW, Zuh X, Han L, Li
E, Nair A, Lee CL, Ho CM |
"Inhibiting elongation factor binding to the malarial
80S ribosome triggers ribosome biogenesis." |
Single particle cryoem structure of the pf80s ribosome
in non-rotated pre state (nrt a-p-e) . SNAP output
|
|
9buq
|
ribosome |
cryo-EM (2.3 Å) |
Anton L, Cheng W, Haile M, Cobb DW, Zhu X, Han L, Li
E, Nair A, Lee CL, Ho CM |
"Inhibition elongation factor binding to the malarial
80S ribosome triggers ribosome biogenesis." |
Single particle cryoem structure of the pf80s ribosome
in the post state (nrt with p- and e-site trna) .
SNAP output
|
|
9bus
|
ribosome |
cryo-EM (2.4 Å) |
Anton L, Cheng W, Haile M, Cobb DW, Zhu X, Han L, Li
E, Nair A, Lee CL, Ho CM |
"Inhibiting elongation factor binding to the malarial
80S ribosome triggers ribosome biogenesis." |
Single particle cryoem structure of the pf80s ribosome
in the unloaded state (nrt with e-site trna) . SNAP output
|
|
9but
|
ribosome |
cryo-EM (2.8 Å) |
Anton L, Cheng W, Haile M, Cobb DW, Zhu X, Han L, Li
E, Nair A, Lee CL, Ho CM |
"Inhibiting elongation factor binding to the malarial
80S ribosome triggers ribosome biogenesis." |
Single particle cryoem structure of the pf80s ribosome
in the rotated-2 pre state (rt state with p and e-site
trna) . SNAP output
|
|
9buu
|
ribosome |
cryo-EM (2.8 Å) |
Anton L, Cheng W, Haile M, Cobb DW, Zhu X, Han L, Li
E, Nair A, Lee CL, Ho CM |
"Inhibiting elongation factor binding to the malarial
80S ribosome triggers ribosome biogenesis." |
Single particle cryoem structure of the pf80s ribosome
in rotated state with e-site trna . SNAP output
|
|
9bwv
|
viral protein-RNA |
cryo-EM (5.1 Å) |
Peng R, Xu X, Nepal B, Gong Y, Li F, Ferretti MB,
Zhou M, Lynch KW, Burslem GM, Kortagere S, Marmorstein R,
Chang YW |
(2025) "Molecular
basis of influenza ribonucleoprotein complex assembly
and processive RNA synthesis." Science,
388, eadq7597. doi: 10.1126/science.adq7597.
|
Structure of influenza d rnp, 4xnp local
resconstruction . SNAP
output
|
|
9c2k
|
RNA |
X-ray (2.42 Å) |
Ojha M, Koirala D |
"Crystal structure of HIV-1 RRE SL2 in complex with
Fab BL3-6." |
The crystal structure of hiv-1 rev response element
stem-loop ii in complex with a fab . SNAP output
|
|
9c3h
|
ribosome |
cryo-EM (2.0 Å) |
Zhu X, Cruz VE, Zhang H, Erzberger JP, Mendell
JT |
(2024) "Specific
tRNAs promote mRNA decay by recruiting the CCR4-NOT
complex to translating ribosomes."
Science, 386, eadq8587. doi:
10.1126/science.adq8587.
|
Structure of the cnot3-bound human 80s ribosome with
trna-arg in the p-site. . SNAP output
|
|
9c3i
|
transcription |
cryo-EM (3.1 Å) |
Zhu X, Cruz VE, Zhang H, Erzberger JP, Mendell
JT |
(2024) "Specific
tRNAs promote mRNA decay by recruiting the CCR4-NOT
complex to translating ribosomes."
Science, 386, eadq8587. doi:
10.1126/science.adq8587.
|
Rebuilt cnot3-trna-leu structure . SNAP output
|
|
9c4g
|
antibiotic |
cryo-EM (2.53 Å) |
Lomakin IB, Devarkar SC, Grada A, Bunick CG |
(2024) "Mechanistic
Basis for the Translation Inhibition of Cutibacterium
acnes by Clindamycin." J Invest Dermatol.,
144, 2553-2561.e3. doi: 10.1016/j.jid.2024.07.013.
|
Cutibacterium acnes 50s ribosomal subunit with
clindamycin bound . SNAP
output
|
|
9c4h
|
viral protein,RNA binding protein-RNA |
cryo-EM (8.6 Å) |
Peng R, Xu X, Nepal B, Gong Y, Li F, Ferretti MB,
Zhou M, Lynch KW, Burslem GM, Kortagere S, Marmorstein R,
Chang YW |
(2025) "Molecular
basis of influenza ribonucleoprotein complex assembly
and processive RNA synthesis." Science,
388, eadq7597. doi: 10.1126/science.adq7597.
|
Double helical structure of influenza d rnp complex .
SNAP output
|
|
9c68
|
antiviral protein-RNA |
X-ray (1.82 Å) |
Baca CF, Majumder P, Hickling JH, Ye L, Teplova M,
Brady SF, Patel DJ, Marraffini LA |
(2024) "The
CRISPR-associated adenosine deaminase Cad1 converts ATP
to ITP to provide antiviral immunity."
Cell, 187, 7183. doi:
10.1016/j.cell.2024.10.002.
|
The crispr associated carf-adenosine deaminase
cad1-carf in the ca6 bound form . SNAP output
|
|
9c69
|
antiviral protein-RNA |
X-ray (2.4 Å) |
Baca CF, Majumder P, Hickling JH, Ye L, Teplova M,
Brady SF, Patel DJ, Marraffini LA |
(2024) "The
CRISPR-associated adenosine deaminase Cad1 converts ATP
to ITP to provide antiviral immunity."
Cell, 187, 7183. doi:
10.1016/j.cell.2024.10.002.
|
The crispr associated carf-adenosine deaminase,
cad1-carf in the ca4 bound form . SNAP output
|
|
9c75
|
RNA-immune system |
X-ray (3.04 Å) |
Ojha M, Koirala D |
"The crystal structure of HIV-1 Rev Response Element
Stem-Loop II G34U mutant in complex with a Fab." |
The crystal structure of hiv-1 rev response element
stem-loop ii g34u mutant in complex with a fab .
SNAP output
|
|
9c77
|
antiviral protein-RNA |
cryo-EM (3.2 Å) |
Baca CF, Majumder P, Hickling JH, Ye L, Teplova M,
Brady SF, Patel DJ, Marraffini LA |
(2024) "The
CRISPR-associated adenosine deaminase Cad1 converts ATP
to ITP to provide antiviral immunity."
Cell, 187, 7183. doi:
10.1016/j.cell.2024.10.002.
|
Cryoem structure of crispr associated effector,
carf-adenosine deaminase 1, cad1, in ca4 bound form
with atp. . SNAP
output
|
|
9c8k
|
RNA |
cryo-EM (3.1 Å) |
Sherlock ME, Langeberg CJ, Segar KE, Kieft JS |
(2025) "A
conserved class of viral RNA structures regulates
translation reinitiation through dynamic ribosome
interactions." Cell Rep,
44, 115236. doi: 10.1016/j.celrep.2025.115236.
|
Rabbit hemorrhagic disease virus reinitiation
stimulating turbs RNA bound to rabbit ribosome .
SNAP output
|
|
9ca4
|
isomerase-RNA |
cryo-EM (3.01 Å) |
Yang X, Chen X, Yang W, Pommier Y |
(2025) "Structural
insights into human topoisomerase 3 beta DNA and RNA
catalysis and nucleic acid gate dynamics." Nat
Commun, 16, 834. doi: 10.1038/s41467-025-55959-y.
|
Human top3b-tdrd3 core complex in RNA rejoining state .
SNAP output
|
|
9cag
|
isomerase-RNA |
cryo-EM (3.33 Å) |
Yang X, Chen X, Yang W, Pommier Y |
(2025) "Structural
insights into human topoisomerase 3 beta DNA and RNA
catalysis and nucleic acid gate dynamics." Nat
Commun, 16, 834. doi: 10.1038/s41467-025-55959-y.
|
Human top3b-tdrd3 core complex in RNA pre-cleavage
state . SNAP output
|
|
9cai
|
ribosome |
cryo-EM (2.59 Å) |
Sehgal E, Wohlenberg C, Soukup EM, Viscardi MJ,
Serrao VHB, Arribere JA |
(2024) "High-resolution
reconstruction of a C. elegans ribosome sheds light on
evolutionary dynamics and tissue specificity."
Rna, 30, 1513-1528. doi:
10.1261/rna.080103.124.
|
High-resolution c. elegans 80s ribosome structure -
class 1 . SNAP
output
|
|
9cdb
|
antiviral protein-RNA |
cryo-EM (3.6 Å) |
Baca CF, Majumder P, Hickling JH, Ye L, Teplova M,
Brady SF, Patel DJ, Marraffini LA |
(2024) "The
CRISPR-associated adenosine deaminase Cad1 converts ATP
to ITP to provide antiviral immunity."
Cell, 187, 7183. doi:
10.1016/j.cell.2024.10.002.
|
Cryoem structure of crispr associated effector,
carf-adenosine deaminase 1, cad1, in ca6 (partial
density) bound form with atp (partial density). .
SNAP output
|
|
9cer
|
RNA binding protein-RNA-DNA |
cryo-EM (4.7 Å) |
Xu P, Saito M, Faure G, Maguire S, Chau-Duy-Tam Vo S,
Wilkinson ME, Kuang H, Wang B, Rice WJ, Macrae RK, Zhang
F |
(2024) "Structural
insights into the diversity and DNA cleavage mechanism
of Fanzor." Cell, 187,
5238-5252.e20. doi: 10.1016/j.cell.2024.07.050.
|
Guillardia theta fanzor (gtfz) state 1 . SNAP output
|
|
9cg5
|
ribosome |
cryo-EM (2.59 Å) |
Mattingly JM, Nguyen HA, Roy B, Fredrick K, Dunham
CM |
(2024) "Structural
analysis of noncanonical translation initiation
complexes." J.Biol.Chem.,
300, 107743. doi: 10.1016/j.jbc.2024.107743.
|
70s initiation complex (trna-fmet m1 + uug start codon)
. SNAP output
|
|
9cg6
|
ribosome |
cryo-EM (2.61 Å) |
Mattingly JM, Nguyen HA, Roy B, Fredrick K, Dunham
CM |
(2024) "Structural
analysis of noncanonical translation initiation
complexes." J.Biol.Chem.,
300, 107743. doi: 10.1016/j.jbc.2024.107743.
|
70s initiation complex (trna-fmet m1 + gug start codon)
. SNAP output
|
|
9cg7
|
ribosome |
cryo-EM (2.75 Å) |
Mattingly JM, Nguyen HA, Roy B, Fredrick K, Dunham
CM |
(2024) "Structural
analysis of noncanonical translation initiation
complexes." J.Biol.Chem.,
300, 107743. doi: 10.1016/j.jbc.2024.107743.
|
70s initiation complex (trna-fmet m1 + aug start codon)
. SNAP output
|
|
9cgv
|
viral protein-RNA-inhibitor |
cryo-EM (2.7 Å) |
Hernandez G, Osinski A, Majumdar A, Eitson JL,
Antczak M, Pawlowski K, Niederstrasser H, Servage KA,
Posner B, Schoggins JW, Ready JM, Tagliabracci VS |
(2025) "Covalent
inhibition of the SARS-CoV-2 NiRAN domain via an
active-site cysteine." J.Biol.Chem.,
108378. doi: 10.1016/j.jbc.2025.108378.
|
Sars-cov-2 nsp12 niran domain bound to a covalent
inhibitor sw090466-1 . SNAP output
|
|
9cl9
|
ribosome |
cryo-EM (5.04 Å) |
Lee J, Sheng K, Williamson JR, Gebert L |
"50S ribosome assembly intermediates at low
temperature reveal bound RluB." |
Wt 12c im fraction, b-b3 with rlub bound . SNAP output
|
|
9cmp
|
hydrolase-RNA |
cryo-EM (3.3 Å) |
Mohamed AA, Wang PY, Bartel DP, Vos SM |
(2025) "The
structural basis for RNA slicing by human
Argonaute2." Cell Rep,
44, 115166. doi: 10.1016/j.celrep.2024.115166.
|
Structure of human argonaute2-guide-target complex in a
fully paired, slicing-competent conformation . SNAP output
|
|
9cn3
|
ribosome-antibiotic |
cryo-EM (2.62 Å) |
Bibel B, Raskar T, Couvillion M, Lee M, Kleinman JI,
Takeuchi-Tomita N, Churchman LS, Fraser JS, Fujimori
DG |
(2025) "Context-specific
inhibition of mitochondrial ribosomes by phenicol and
oxazolidinone antibiotics." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkaf046.
|
Human 39s mitoribosome in complex with antibiotic
linezolid . SNAP
output
|
|
9cpo
|
viral protein |
cryo-EM (3.5 Å) |
Hoferle PJ, Anderson TK, Kirchdoerfer RN |
(2024) "A
genus-specific nsp12 region impacts polymerase assembly
in Alpha- and Gammacoronaviruses."
Biorxiv. doi: 10.1101/2024.07.23.604833.
|
Infectious bronchitis virus core polymerase complex .
SNAP output
|
|
9d0j
|
ribosome |
X-ray (2.5 Å) |
Tresco BIC, Wu KJY, Ramkissoon A, Aleksandrova EV,
Purdy M, See DNY, Liu RY, Polikanov YS, Myers AG |
(2025) "Discovery
of a fluorinated macrobicyclic antibiotic through
chemical synthesis." Nat.Chem.,
17, 582-589. doi: 10.1038/s41557-025-01738-7.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with bt-33, mrna, deacylated
a-site trnaphe, aminoacylated p-site fmet-trnamet, and
deacylated e-site trnaphe at 2.50a resolution .
SNAP output
|
|
9d5j
|
RNA binding protein-RNA |
X-ray (2.8 Å) |
Manjunath A, Cheng J, Campbell KB, Jacobsen CS,
Mendoza HG, Bierbaum L, Jauregui-Matos V, Doherty EE,
Fisher AJ, Beal PA |
(2024) "Nucleoside
Analogs in ADAR Guide Strands Enable Editing at 5'-G A
Sites." Biomolecules, 14.
doi: 10.3390/biom14101229.
|
Human adenosine deaminase acting on dsrna (adar2-rd)
bound to dsrna containing deoxyinosine at the -1
position of the guide strand . SNAP output
|
|
9d5k
|
RNA binding protein-RNA |
X-ray (2.697 Å) |
Manjunath A, Cheng J, Campbell KB, Jacobsen CS,
Mendoza HG, Bierbaum L, Jauregui-Matos V, Doherty EE,
Fisher AJ, Beal PA |
(2024) "Nucleoside
Analogs in ADAR Guide Strands Enable Editing at 5'-G A
Sites." Biomolecules, 14.
doi: 10.3390/biom14101229.
|
Human adenosine deaminase acting on dsrna (adar2-rd)
bound to dsrna containing an expanded cytidine analog
at the -1 position of the guide strand . SNAP output
|
|
9d7r
|
ribosome |
X-ray (2.7 Å) |
Huang W, Baliga C, Aleksandrova EV, Atkinson G,
Polikanov YS, Vazquez-Laslop N, Mankin AS |
(2024) "Activity,
structure, and diversity of Type II proline-rich
antimicrobial peptides from insects." Embo
Rep., 25, 5194-5211. doi:
10.1038/s44319-024-00277-5.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with fva1 antimicrobial
peptide, mrna, a-site release factor 1, and deacylated
p-site and e-site trnaphe at 2.70a resolution .
SNAP output
|
|
9d7s
|
ribosome |
X-ray (2.85 Å) |
Huang W, Baliga C, Aleksandrova EV, Atkinson G,
Polikanov YS, Vazquez-Laslop N, Mankin AS |
(2024) "Activity,
structure, and diversity of Type II proline-rich
antimicrobial peptides from insects." Embo
Rep., 25, 5194-5211. doi:
10.1038/s44319-024-00277-5.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with api antimicrobial peptide,
mrna, a-site release factor 1, and deacylated p-site
and e-site trnaphe at 2.85a resolution . SNAP output
|
|
9d7t
|
ribosome |
X-ray (2.7 Å) |
Huang W, Baliga C, Aleksandrova EV, Atkinson G,
Polikanov YS, Vazquez-Laslop N, Mankin AS |
(2024) "Activity,
structure, and diversity of Type II proline-rich
antimicrobial peptides from insects." Embo
Rep., 25, 5194-5211. doi:
10.1038/s44319-024-00277-5.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with api137 antimicrobial
peptide, mrna, a-site release factor 1, and deacylated
p-site and e-site trnaphe at 2.70a resolution .
SNAP output
|
|
9d85
|
RNA binding protein-RNA |
cryo-EM (3.59 Å) |
Ona Chuquimarca SM, Beenstock J, Daou S, Porat J,
Keszei AFA, Yin JZ, Beschauner T, Bayfield MA,
Mazhab-Jafari MT, Sicheri F |
(2024) "Structures
of KEOPS bound to tRNA reveal functional roles of the
kinase Bud32." Nat Commun,
15, 10633. doi: 10.1038/s41467-024-54787-w.
|
Structure of the keops complex (cgi121-bud32-kae1-pcc1)
bound to trna in a distorted trna conformation .
SNAP output
|
|
9d89
|
ribosome |
cryo-EM (1.95 Å) |
Panteleev PV, Pichkur EB, Kruglikov RN, Paleskava A,
Shulenina OV, Bolosov IA, Bogdanov IV, Safronova VN,
Balandin SV, Marina VI, Kombarova TI, Korobova OV,
Shamova OV, Myasnikov AG, Borzilov AI, Osterman IA,
Sergiev PV, Bogdanov AA, Dontsova OA, Konevega AL,
Ovchinnikova TV |
(2024) "Rumicidins
are a family of mammalian host-defense peptides
plugging the 70S ribosome exit tunnel." Nat
Commun, 15, 8925. doi: 10.1038/s41467-024-53309-y.
|
E. coli 50s ribosomal subunit in complex with pramp
rumicidin-2 (focused refinement) . SNAP output
|
|
9dcf
|
RNA binding protein-RNA |
X-ray (2.87 Å) |
Dias-Solange D, Le MT, Gottipati K, Choi KH |
(2025) "Structure
of coxsackievirus cloverleaf RNA and 3C pro dimer
establishes the RNA-binding mechanism of enterovirus
protease 3C pro." Sci Adv,
11, eads6862. doi: 10.1126/sciadv.ads6862.
|
Structure of coxsackievirus b3 cloverleaf RNA in
complex with 3cpro dimer . SNAP output
|
|
9dch
|
gene regulation |
cryo-EM (3.4 Å) |
Song J, Yao L, Gooding AR, Thron V, Kasinath V, Cech
TR |
(2024) "Diverse
RNA Structures Induce PRC2 Dimerization and Inhibit
Histone Methyltransferase Activity."
Biorxiv. doi: 10.1101/2024.08.29.610323.
|
Single-stranded RNA-mediated prc2 dimer . SNAP output
|
|
9de5
|
RNA-transcription |
X-ray (2.75 Å) |
Bou-Nader C, Link KA, Suddala KC, Knutson JR, Zhang
J |
(2025) "Structures
of complete HIV-1 TAR RNA portray a dynamic platform
poised for protein binding and structural
remodeling." Nat Commun,
16, 2252. doi: 10.1038/s41467-025-57519-w.
|
Structure of full-length hiv tar RNA bound to hiv tat
RNA-binding domain . SNAP output
|
|
9dfc
|
ribosome |
X-ray (2.5 Å) |
Wright G, Jangra M, Travin D, Aleksandrova E, Kaur M,
Darwish L, Koteva K, Klepacki D, Wang W, Tiffany M,
Sokaribo A, Coombes B, Vazquez-Laslop N, Polikanov Y,
Mankin A |
(2024) "A Broad
Spectrum Lasso Peptide Antibiotic Targeting the
Bacterial Ribosome." Res Sq. doi: 10.21203/rs.3.rs-5058118/v1.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with lasso peptide lariocidin,
mrna, aminoacylated a-site phe-trnaphe, aminoacylated
p-site fmet-trnamet, and deacylated e-site trnaphe at
2.50a resolution . SNAP
output
|
|
9dfd
|
ribosome |
X-ray (2.6 Å) |
Wright G, Jangra M, Travin D, Aleksandrova E, Kaur M,
Darwish L, Koteva K, Klepacki D, Wang W, Tiffany M,
Sokaribo A, Coombes B, Vazquez-Laslop N, Polikanov Y,
Mankin A |
(2024) "A Broad
Spectrum Lasso Peptide Antibiotic Targeting the
Bacterial Ribosome." Res Sq. doi: 10.21203/rs.3.rs-5058118/v1.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with lasso peptide lariocidin
b, mrna, aminoacylated a-site phe-trnaphe,
aminoacylated p-site fmet-trnamet, and deacylated
e-site trnaphe at 2.60a resolution . SNAP output
|
|
9dfe
|
ribosome |
X-ray (2.6 Å) |
Wright G, Jangra M, Travin D, Aleksandrova E, Kaur M,
Darwish L, Koteva K, Klepacki D, Wang W, Tiffany M,
Sokaribo A, Coombes B, Vazquez-Laslop N, Polikanov Y,
Mankin A |
(2024) "A Broad
Spectrum Lasso Peptide Antibiotic Targeting the
Bacterial Ribosome." Res Sq. doi: 10.21203/rs.3.rs-5058118/v1.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with lasso peptide lariocidin
and protein y at 2.60a resolution . SNAP output
|
|
9dn4
|
immune system |
X-ray (1.9 Å) |
Hegde S, Akhter S, Tang Z, Qi C, Yu C, Lewicka A, Liu
Y, Koirala K, Reibarkh M, Battaile KP, Cooper A, Lovell
S, Holmstrom ED, Wang X, Piccirilli JA, Gao Q, Miao Y,
Wang J |
(2025) "Mechanistic
studies of small molecule ligands selective to RNA
single G bulges." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf559.
|
Crystal structure of a sars-cov-2 20-mer RNA in complex
with fab bl3-6s97n . SNAP output
|
|
9dow
|
translation |
cryo-EM (3.1 Å) |
Devarkar SC, Budding CR, Pathirage C, Kavoor A,
Herbert C, Limbach PA, Musier-Forsyth K, Xiong Y |
(2025) "Structural
basis for aminoacylation of cellular modified tRNALys3
by human lysyl-tRNA synthetase." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkaf114.
|
H-lysrs bound to unmodified trna-lys3 (undocked state,
amp bound) . SNAP
output
|
|
9dpa
|
translation |
cryo-EM (3.0 Å) |
Devarkar SC, Budding CR, Pathirage C, Kavoor A,
Herbert C, Limbach PA, Musier-Forsyth K, Xiong Y |
(2025) "Structural
basis for aminoacylation of cellular modified tRNALys3
by human lysyl-tRNA synthetase." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkaf114.
|
Human lysrs bound to unmodified trna-lys3 (3'-cca
docked state, amp bound) . SNAP output
|
|
9dpb
|
translation |
cryo-EM (2.9 Å) |
Devarkar SC, Budding CR, Pathirage C, Kavoor A,
Herbert C, Limbach PA, Musier-Forsyth K, Xiong Y |
(2025) "Structural
basis for aminoacylation of cellular modified tRNALys3
by human lysyl-tRNA synthetase." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkaf114.
|
Human lysrs bound to unmodified trna-lys3 (undocked
state, ampcpp bound) . SNAP output
|
|
9dpl
|
translation |
cryo-EM (2.8 Å) |
Devarkar SC, Budding CR, Pathirage C, Kavoor A,
Herbert C, Limbach PA, Musier-Forsyth K, Xiong Y |
(2025) "Structural
basis for aminoacylation of cellular modified tRNALys3
by human lysyl-tRNA synthetase." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkaf114.
|
Human lysrs bound to cellular modified trna-lys3 and
aimp2 . SNAP output
|
|
9drs
|
ligase-RNA |
X-ray (2.35 Å) |
Gade P, Chang C, Pryde DS, Fletcher D, Niven S,
Magalhaes LG, Robinson D, Saini J, Ibrahim PEGF, Forte B,
Wower J, Bodkin MJ, Baragana B, Gilbert IH, Michalska K,
Joachimiak A |
(2025) "Different
chemical scaffolds bind to L-phe site in Mycobacterium
tuberculosis Phe-tRNA synthetase."
Eur.J.Med.Chem., 287, 117335.
doi: 10.1016/j.ejmech.2025.117335.
|
Crystal structure of m. tuberculosis phers-trna complex
bound to inhibitor d-116 . SNAP output
|
|
9drt
|
ligase-RNA |
X-ray (2.51 Å) |
Gade P, Chang C, Pryde DS, Fletcher D, Niven S,
Magalhaes LG, Robinson D, Saini J, Ibrahim PEGF, Forte B,
Wower J, Bodkin MJ, Baragana B, Gilbert IH, Michalska K,
Joachimiak A |
(2025) "Different
chemical scaffolds bind to L-phe site in Mycobacterium
tuberculosis Phe-tRNA synthetase."
Eur.J.Med.Chem., 287, 117335.
doi: 10.1016/j.ejmech.2025.117335.
|
Crystal structure of the complex of m. tuberculosis
phers with cognate precursor trna and fragment
ddd00805735 . SNAP
output
|
|
9drv
|
ligase |
X-ray (2.46 Å) |
Gade P, Chang C, Pryde DS, Fletcher D, Niven S,
Magalhaes LG, Robinson D, Saini J, Ibrahim PEGF, Forte B,
Wower J, Bodkin MJ, Baragana B, Gilbert IH, Michalska K,
Joachimiak A |
(2025) "Different
chemical scaffolds bind to L-phe site in Mycobacterium
tuberculosis Phe-tRNA synthetase."
Eur.J.Med.Chem., 287, 117335.
doi: 10.1016/j.ejmech.2025.117335.
|
Crystal structure of m. tuberculosis phers-trna complex
bound to inhibitor d-004 . SNAP output
|
|
9dsx
|
ligase-RNA |
X-ray (2.05 Å) |
Gade P, Chang C, Pryde DS, Fletcher D, Niven S,
Magalhaes LG, Robinson D, Saini J, Ibrahim PEGF, Forte B,
Wower J, Bodkin MJ, Baragana B, Gilbert IH, Michalska K,
Joachimiak A |
(2025) "Different
chemical scaffolds bind to L-phe site in Mycobacterium
tuberculosis Phe-tRNA synthetase."
Eur.J.Med.Chem., 287, 117335.
doi: 10.1016/j.ejmech.2025.117335.
|
Crystal structure of the complex of m. tuberculosis
phers with cognate precursor trna and fragment
ddd00107555 . SNAP
output
|
|
9dtf
|
ligase-RNA |
X-ray (2.45 Å) |
Gade P, Chang C, Pryde DS, Fletcher D, Niven S,
Magalhaes LG, Robinson D, Saini J, Ibrahim PEGF, Forte B,
Wower J, Bodkin MJ, Baragana B, Gilbert IH, Michalska K,
Joachimiak A |
(2025) "Different
chemical scaffolds bind to L-phe site in Mycobacterium
tuberculosis Phe-tRNA synthetase."
Eur.J.Med.Chem., 287, 117335.
doi: 10.1016/j.ejmech.2025.117335.
|
Crystal structure of the complex of m. tuberculosis
phers with cognate precursor trna and fragment
ddd01008876 . SNAP
output
|
|
9dtr
|
splicing |
cryo-EM (2.31 Å) |
Senn KA, Lipinski KA, Zeps NJ, Griffin AF, Wilkinson
ME, Hoskins AA |
(2024) "Control
of 3' splice site selection by the yeast splicing
factor Fyv6." Biorxiv. doi: 10.1101/2024.05.04.592262.
|
Structure of the yeast post-catalytic p complex
spliceosome at 2.3 angstrom resolution . SNAP output
|
|
9dts
|
translation, hydrolase-RNA |
X-ray (1.69 Å) |
Conley JF, Brown LE, McNeely JH, Pelletier J, Porco
Jr JA, Allen KN |
(2025) "Structural
Basis for the Improved RNA Clamping of
Amidino-Rocaglates to eIF4A1." Acs Omega,
10, 5795-5808. doi: 10.1021/acsomega.4c09421.
|
Crystal structure of the human
eif4a1-amppnp-amidino-rocaglate-polypurine RNA complex
. SNAP output
|
|
9dtt
|
viral protein-RNA |
cryo-EM (3.6 Å) |
Obi JO, Kihn KC, McQueen L, Fields JK, Snyder GA,
Deredge DJ |
(2024) "Structural
Dynamics of the Dengue Virus Non-structural 5 (NS5)
Interactions with Promoter Stem Loop A (SLA)."
Biorxiv. doi: 10.1101/2024.12.03.626708.
|
cryo-EM structure of denv2 ns5 in complex with stem
loop a (sla) . SNAP
output
|
|
9duk
|
ribosome |
cryo-EM (2.56 Å) |
Boyko KV, Bernstein RA, Kim M, Cate JHD |
(2025) "Role of
Ribosomal Protein bS1 in Orthogonal mRNA Start Codon
Selection." Biochemistry,
64, 710-718. doi: 10.1021/acs.biochem.4c00688.
|
Structure of mutant 30s subunit with extended helix 26,
version 3 . SNAP
output
|
|
9dul
|
ribosome |
cryo-EM (2.56 Å) |
Boyko KV, Bernstein RA, Kim M, Cate JHD |
(2025) "Role of
Ribosomal Protein bS1 in Orthogonal mRNA Start Codon
Selection." Biochemistry,
64, 710-718. doi: 10.1021/acs.biochem.4c00688.
|
Structure of mutant 30s subunit with extended helix 26,
version 4 . SNAP
output
|
|
9dyg
|
ribosome |
cryo-EM (5.27 Å) |
Sheng K, Dong X, Aiyer S, Lee J, Djordjevic-Marquardt
S, Lyumkis D, Williamson JR |
"Domain consolidation in bacterial 50S assembly
revealed by anti-sense oligonucleotide probing." |
Isat-pna-ra20, ra20-b-c class . SNAP output
|
|
9e6q
|
ribosome |
cryo-EM (1.95 Å) |
Nissley AJ, Shulgina Y, Kivimae RW, Downing BE, Penev
PI, Banfield JF, Nayak DD, Cate JHD |
"Structure of an Archaeal Ribosome with a Divergent
Active Site." |
cryo-EM structure of the pyrobaculum calidifontis 50s
ribosomal subunit in complex with dri . SNAP output
|
|
9e71
|
ribosome |
cryo-EM (2.36 Å) |
Nissley AJ, Shulgina Y, Kivimae RW, Downing BE, Penev
PI, Banfield JF, Nayak DD, Cate JHD |
"Structure of an Archaeal Ribosome with a Divergent
Active Site." |
cryo-EM structure of the pyrobaculum calidifontis 70s
ribosome . SNAP
output
|
|
9e7d
|
RNA |
X-ray (3.11 Å) |
Ojha M, Koirala D |
"Crystal structure of HIV-1 RRE SLII A31C mutant in
complex with Fab BL3-6." |
Crystal structure of hiv-1 rre slii a31c mutant in
complex with fab bl3-6 . SNAP output
|
|
9e7e
|
RNA |
X-ray (2.75 Å) |
Ojha M, Koirala D |
"Crystal structure of HIV-1 RRE SLII A31CG39C mutant
in complex with Fab BL3-6." |
Crystal structure of hiv-1 rre slii a31cg39c mutant in
complex with fab bl3-6 . SNAP output
|
|
9e7f
|
ribosome |
cryo-EM (2.53 Å) |
Nissley AJ, Shulgina Y, Kivimae RW, Downing BE, Penev
PI, Banfield JF, Nayak DD, Cate JHD |
"Structure of an Archaeal Ribosome with a Divergent
Active Site." |
cryo-EM structure of the pyrobaculum calidifontis 70s
ribosome in complex with dri . SNAP output
|
|
9e7g
|
RNA |
X-ray (3.0 Å) |
Ojha M, Koirala D |
"Crystal structure of HIV-1 RRE SLII G34C mutant in
complex with Fab BL3-6." |
Crystal structure of hiv-1 rre slii g34c mutant in
complex with fab bl3-6 . SNAP output
|
|
9enb
|
RNA binding protein |
cryo-EM (2.66 Å) |
Lin TY, Kleemann L, Jezowski J, Dobosz D, Rawski M,
Indyka P, Wazny G, Mehta R, Chramiec-Glabik A, Koziej L,
Ranff T, Fufezan C, Wawro M, Kochan J, Bereta J, Leidel
SA, Glatt S |
(2024) "The
molecular basis of tRNA selectivity by human
pseudouridine synthase 3." Mol.Cell,
84, 2472-2489.e8. doi: 10.1016/j.molcel.2024.06.013.
|
Human pseudouridine synthase 3 (pus3 r116a mutant) and
two trna-gln . SNAP
output
|
|
9enc
|
RNA binding protein |
cryo-EM (3.36 Å) |
Lin TY, Kleemann L, Jezowski J, Dobosz D, Rawski M,
Indyka P, Wazny G, Mehta R, Chramiec-Glabik A, Koziej L,
Ranff T, Fufezan C, Wawro M, Kochan J, Bereta J, Leidel
SA, Glatt S |
(2024) "The
molecular basis of tRNA selectivity by human
pseudouridine synthase 3." Mol.Cell,
84, 2472-2489.e8. doi: 10.1016/j.molcel.2024.06.013.
|
Human pseudouridine synthase 3 (pus3 r116a mutant) and
one trna-gln . SNAP
output
|
|
9ene
|
RNA binding protein |
cryo-EM (3.15 Å) |
Lin TY, Kleemann L, Jezowski J, Dobosz D, Rawski M,
Indyka P, Wazny G, Mehta R, Chramiec-Glabik A, Koziej L,
Ranff T, Fufezan C, Wawro M, Kochan J, Bereta J, Leidel
SA, Glatt S |
(2024) "The
molecular basis of tRNA selectivity by human
pseudouridine synthase 3." Mol.Cell,
84, 2472-2489.e8. doi: 10.1016/j.molcel.2024.06.013.
|
Human pseudouridine synthase 3 (pus3 d118a mutant) and
two trna-arg . SNAP
output
|
|
9enf
|
RNA binding protein |
cryo-EM (2.97 Å) |
Lin TY, Kleemann L, Jezowski J, Dobosz D, Rawski M,
Indyka P, Wazny G, Mehta R, Chramiec-Glabik A, Koziej L,
Ranff T, Fufezan C, Wawro M, Kochan J, Bereta J, Leidel
SA, Glatt S |
(2024) "The
molecular basis of tRNA selectivity by human
pseudouridine synthase 3." Mol.Cell,
84, 2472-2489.e8. doi: 10.1016/j.molcel.2024.06.013.
|
Human pseudouridine synthase 3 (pus3 d118a mutant) and
two pre-trna-arg . SNAP
output
|
|
9ere
|
hydrolase |
cryo-EM (2.82 Å) |
Kugler M, Metzner FJ, Witte G, Hopfner KP, Lammens
K |
(2024) "Phosphorylation-mediated
conformational change regulates human SLFN11."
Nat Commun, 15, 10500. doi:
10.1038/s41467-024-54833-7.
|
Slfn11 dimer bound to trna-leu-taa . SNAP output
|
|
9erf
|
hydrolase |
cryo-EM (2.64 Å) |
Kugler M, Metzner FJ, Witte G, Hopfner KP, Lammens
K |
(2024) "Phosphorylation-mediated
conformational change regulates human SLFN11."
Nat Commun, 15, 10500. doi:
10.1038/s41467-024-54833-7.
|
Slfn11 dimer bound to trna-met-cat . SNAP output
|
|
9esh
|
splicing |
cryo-EM (3.2 Å) |
Soni K, Horvath A, Dybkov O, Schwan M, Trakansuebkul
S, Flemming D, Wild K, Urlaub H, Fischer T, Sinning
I |
(2025) "Structures
of aberrant spliceosome intermediates on their way to
disassembly." Nat.Struct.Mol.Biol.,
32, 914-925. doi: 10.1038/s41594-024-01480-7.
|
Structure of a b-state intermediate committed to
discard (bd-i state) . SNAP output
|
|
9esi
|
splicing |
cryo-EM (3.1 Å) |
Soni K, Horvath A, Dybkov O, Schwan M, Trakansuebkul
S, Flemming D, Wild K, Urlaub H, Fischer T, Sinning
I |
(2025) "Structures
of aberrant spliceosome intermediates on their way to
disassembly." Nat.Struct.Mol.Biol.,
32, 914-925. doi: 10.1038/s41594-024-01480-7.
|
Structure of a b-state intermediate committed to
discard (bd-ii state) . SNAP output
|
|
9ey0
|
RNA binding protein |
cryo-EM (2.78 Å) |
Valentin Gese G, Hallberg BM |
(2024) "Structural
basis of 3'-tRNA maturation by the human mitochondrial
RNase Z complex." Embo J.,
43, 6573-6590. doi: 10.1038/s44318-024-00297-w.
|
Human mitochondrial rnase z with trna-his . SNAP output
|
|
9ey1
|
RNA binding protein |
cryo-EM (2.9 Å) |
Valentin Gese G, Hallberg BM |
(2024) "Structural
basis of 3'-tRNA maturation by the human mitochondrial
RNase Z complex." Embo J.,
43, 6573-6590. doi: 10.1038/s44318-024-00297-w.
|
Human mitochondrial rnase z with trna-his precursor .
SNAP output
|
|
9ey2
|
RNA binding protein |
cryo-EM (2.96 Å) |
Valentin Gese G, Hallberg BM |
(2024) "Structural
basis of 3'-tRNA maturation by the human mitochondrial
RNase Z complex." Embo J.,
43, 6573-6590. doi: 10.1038/s44318-024-00297-w.
|
Human mitochondrial rnase z with trna-his-cca .
SNAP output
|
|
9eyi
|
hydrolase |
cryo-EM (2.75 Å) |
Smalakyte D, Ruksenaite A, Sasnauskas G, Tamulaitiene
G, Tamulaitis G |
(2024) "Filament
formation activates protease and ring nuclease
activities of CRISPR Lon-SAVED." Mol.Cell,
84, 4239-4255.e8. doi: 10.1016/j.molcel.2024.09.002.
|
cryo-EM structure of saved-lon protease ccacalpl
filament bound to a4p . SNAP output
|
|
9eyj
|
hydrolase |
cryo-EM (2.97 Å) |
Smalakyte D, Ruksenaite A, Sasnauskas G, Tamulaitiene
G, Tamulaitis G |
(2024) "Filament
formation activates protease and ring nuclease
activities of CRISPR Lon-SAVED." Mol.Cell,
84, 4239-4255.e8. doi: 10.1016/j.molcel.2024.09.002.
|
cryo-EM structure of saved-lon protease ccacalpl
filament bound to ca4 . SNAP output
|
|
9eyk
|
hydrolase |
cryo-EM (2.84 Å) |
Smalakyte D, Ruksenaite A, Sasnauskas G, Tamulaitiene
G, Tamulaitis G |
(2024) "Filament
formation activates protease and ring nuclease
activities of CRISPR Lon-SAVED." Mol.Cell,
84, 4239-4255.e8. doi: 10.1016/j.molcel.2024.09.002.
|
cryo-EM structure of saved-lon protease ccacalpl
filament bound to a4>p . SNAP output
|
|
9f0j
|
immune system |
cryo-EM (3.35 Å) |
Singh R, Joiner JD, Herrero Del Valle A, Zwaagstra M,
Jobe I, Ferguson BJ, van Kuppeveld FJM, Modis Y |
(2025) "Molecular
basis of autoimmune disease protection by MDA5
variants." Cell Rep, 44,
115754. doi: 10.1016/j.celrep.2025.115754.
|
cryo-EM structure of the i923v mda5-dsrna filament
without nucleotide . SNAP output
|
|
9f1b
|
translation |
cryo-EM (3.01 Å) |
Lentzsch AM, Yudin D, Gamerdinger M, Chandrasekar S,
Rabl L, Scaiola A, Deuerling E, Ban N, Shan SO |
(2024) "NAC
guides a ribosomal multienzyme complex for nascent
protein processing." Nature,
633, 718-724. doi: 10.1038/s41586-024-07846-7.
|
Mammalian ternary complex of a translating 80s
ribosome, nac and nata-e . SNAP output
|
|
9f1c
|
translation |
cryo-EM (3.78 Å) |
Lentzsch AM, Yudin D, Gamerdinger M, Chandrasekar S,
Rabl L, Scaiola A, Deuerling E, Ban N, Shan SO |
(2024) "NAC
guides a ribosomal multienzyme complex for nascent
protein processing." Nature,
633, 718-724. doi: 10.1038/s41586-024-07846-7.
|
Mammalian quaternary complex of a translating 80s
ribosome, nac, metap1 and nata-e . SNAP output
|
|
9f1d
|
translation |
cryo-EM (3.26 Å) |
Lentzsch AM, Yudin D, Gamerdinger M, Chandrasekar S,
Rabl L, Scaiola A, Deuerling E, Ban N, Shan SO |
(2024) "NAC
guides a ribosomal multienzyme complex for nascent
protein processing." Nature,
633, 718-724. doi: 10.1038/s41586-024-07846-7.
|
Mammalian quaternary complex of a translating 80s
ribosome, nac, metap1 and nata-e-hypk . SNAP output
|
|
9f1u
|
immune system |
cryo-EM (3.67 Å) |
Singh R, Joiner JD, Herrero Del Valle A, Zwaagstra M,
Jobe I, Ferguson BJ, van Kuppeveld FJM, Modis Y |
(2025) "Molecular
basis of autoimmune disease protection by MDA5
variants." Cell Rep, 44,
115754. doi: 10.1016/j.celrep.2025.115754.
|
cryo-EM structure of the i923v mda5-dsrna filament with
adp-alf4 bound and 81-degree helical twist . SNAP output
|
|
9f20
|
immune system |
cryo-EM (4.13 Å) |
Singh R, Joiner JD, Herrero Del Valle A, Zwaagstra M,
Jobe I, Ferguson BJ, van Kuppeveld FJM, Modis Y |
(2025) "Molecular
basis of autoimmune disease protection by MDA5
variants." Cell Rep, 44,
115754. doi: 10.1016/j.celrep.2025.115754.
|
cryo-EM structure of the i923v mda5-dsrna filament with
adp-alf4 bound and 88-degree helical twist . SNAP output
|
|
9f2l
|
immune system |
cryo-EM (3.86 Å) |
Singh R, Joiner JD, Herrero Del Valle A, Zwaagstra M,
Jobe I, Ferguson BJ, van Kuppeveld FJM, Modis Y |
(2025) "Molecular
basis of autoimmune disease protection by MDA5
variants." Cell Rep, 44,
115754. doi: 10.1016/j.celrep.2025.115754.
|
cryo-EM structure of the i923v mda5-dsrna filament with
adp-alf4 bound and 73-degree helical twist . SNAP output
|
|
9f2r
|
viral protein |
X-ray (1.959 Å) |
Cusack S, Drncova P, Krischuns T, Naffakh N |
"High-resolution structure of a
replication-initiation like configuration of influenza
polymerase active site visualises the essential role of a
conserved dibasic motif in the PA subunit." |
Influenza a-h17n10 polymerase with bound promoter and
3' end of template in active site . SNAP output
|
|
9f2w
|
immune system |
cryo-EM (4.21 Å) |
Singh R, Joiner JD, Herrero Del Valle A, Zwaagstra M,
Jobe I, Ferguson BJ, van Kuppeveld FJM, Modis Y |
(2025) "Molecular
basis of autoimmune disease protection by MDA5
variants." Cell Rep, 44,
115754. doi: 10.1016/j.celrep.2025.115754.
|
cryo-EM structure of the i923v mda5-dsrna filament in
complex with atp . SNAP
output
|
|
9f37
|
viral protein |
X-ray (1.905 Å) |
Cusack S, Drncova P, Krischuns T, Naffakh N |
(2024) "High-resolution structure of a
replication-initiation like configuration of influenza
polymerase active site visualises the essential role of
a conserved dibasic motif in the PA subunit."
Biorxiv. doi: 10.1101/2023.11.20.567839.
|
Replication-like initiation state of influenza
polymerase with gtp and ctp at respectively the -1 and
+1 positions (strain a-little yellow-shouldered
bat-guatemala-060-2010-h17n10) . SNAP output
|
|
9f3p
|
immune system |
cryo-EM (3.97 Å) |
Singh R, Joiner JD, Herrero Del Valle A, Zwaagstra M,
Jobe I, Ferguson BJ, van Kuppeveld FJM, Modis Y |
(2025) "Molecular
basis of autoimmune disease protection by MDA5
variants." Cell Rep, 44,
115754. doi: 10.1016/j.celrep.2025.115754.
|
cryo-EM structure of the a946t mda5-dsrna filament .
SNAP output
|
|
9f58
|
ribosome |
cryo-EM (3.1 Å) |
Paternoga H, Xia L, Dimitrova-Paternoga L, Li S, Yan
LL, Oestereich M, Kasvandik S, Nanjaraj Urs AN, Beckert
B, Tenson T, Zaher H, Inada T, Wilson DN |
(2025) "Structure
of a Gcn2 dimer in complex with the large 60S ribosomal
subunit." Proc.Natl.Acad.Sci.USA,
122, e2415807122. doi: 10.1073/pnas.2415807122.
|
Gcn2 dimer bound to the 60s ribosomal subunit .
SNAP output
|
|
9f67
|
RNA binding protein |
cryo-EM (2.8 Å) |
Bernhard H, Petrzilkova H, Popelarova B, Ziemkiewicz
K, Bartosik K, Warminski M, Tengo L, Groger H, Dolce LG,
Mackereth CD, Micura R, Jemielity J, Kowalinski E |
(2025) "Structural
basis of Spliced Leader RNA recognition by the
Trypanosoma brucei cap-binding complex." Nat
Commun, 16, 685. doi: 10.1038/s41467-024-55373-w.
|
Trypanosoma brucei nuclear cap-binding complex (cbc)
bound to cap4 . SNAP
output
|
|
9f7m
|
hydrolase |
X-ray (1.65 Å) |
Mortensen S, Kuncova S, Lormand JD, Myers TM, Kim SK,
Lee VT, Winkler WC, Sondermann H |
(2025) "Structural
and bioinformatics analyses identify
deoxydinucleotide-specific nucleases and their
association with genomic islands in gram-positive
bacteria." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkae1235.
|
Blastococcus orn bound to pgg . SNAP output
|
|
9f9s
|
ribosome |
cryo-EM (2.9 Å) |
Kim KQ, Li JJ, Nanjaraj Urs AN, Pacheco ME, Lasehinde
V, Denk T, Tesina P, Tomomatsu S, Matsuo Y, McDonald E,
Beckmann R, Inada T, Green R, Zaher HS |
(2024) "Multiprotein
bridging factor 1 is required for robust activation of
the integrated stress response on collided
ribosomes." Mol.Cell, 84,
4594. doi: 10.1016/j.molcel.2024.10.029.
|
Yeast sdd1 disome with mbf1 . SNAP output
|
|
9fbv
|
ribosome |
cryo-EM (2.4 Å) |
Koller TO, Berger MJ, Morici M, Paternoga H, Bulatov
T, Di Stasi A, Dang T, Mainz A, Raulf K, Crowe-McAuliffe
C, Scocchi M, Mardirossian M, Beckert B, Vazquez-Laslop
N, Mankin A, Sussmuth RD, Wilson DN |
(2024) "Paenilamicins
from the honey bee pathogen Paenibacillus larvae are
context-specific translocation inhibitors of protein
synthesis." Biorxiv. doi: 10.1101/2024.05.21.595107.
|
70s escherichia coli ribosome with p-site initiatior
trna. . SNAP output
|
|
9fco
|
translation |
cryo-EM (2.4 Å) |
Safdari HA, Morici M, Sanchez-Castro A, Dallape A,
Paternoga H, Giuliodori AM, Fabbretti A, Milon P, Wilson
DN |
(2025) "The
translation inhibitors kasugamycin, edeine and GE81112
target distinct steps during 30S initiation complex
formation." Nat Commun,
16, 2470. doi: 10.1038/s41467-025-57731-8.
|
Structure of e. coli 30s-if1-if3-mrna-kasugamycin
complex . SNAP
output
|
|
9fcv
|
RNA binding protein |
cryo-EM (3.09 Å) |
Wandera KG, Schmelz S, Migur A, Kibe A, Lukat P,
Achmedov T, Caliskan N, Blankenfeldt W, Beisel CL |
(2025) "AcrVIB1
inhibits CRISPR-Cas13b immunity by promoting
unproductive crRNA binding accessible to RNase
attack." Mol.Cell, 85,
1162. doi: 10.1016/j.molcel.2025.01.020.
|
Cas nuclease-crispr (cr)RNA ribonucleoprotein (rnp)
complex . SNAP
output
|
|
9fda
|
translation |
cryo-EM (2.0 Å) |
Safdari HA, Morici M, Sanchez-Castro A, Dallape A,
Paternoga H, Giuliodori AM, Fabbretti A, Milon P, Wilson
DN |
(2025) "The
translation inhibitors kasugamycin, edeine and GE81112
target distinct steps during 30S initiation complex
formation." Nat Commun,
16, 2470. doi: 10.1038/s41467-025-57731-8.
|
Structure of e. coli 30s-if1-if3-mrna-edeine complex .
SNAP output
|
|
9fhl
|
translation |
cryo-EM (2.5 Å) |
Bourgeois G, Coureux PD, Lazennec-Schurdevin C, Madru
C, Gaillard T, Duchateau M, Chamot-Rooke J, Bourcier S,
Mechulam Y, Schmitt E |
(2025) "Structures
of Saccharolobus solfataricus initiation complexes with
leaderless mRNAs highlight archaeal features and
eukaryotic proximity." Nat Commun,
16, 348. doi: 10.1038/s41467-024-55718-5.
|
High-resolution cryo-EM structure of saccharolobus
solfataricus 30s ribosomal subunit bound to mrna and
initiator trna . SNAP
output
|
|
9fi8
|
ribosome |
cryo-EM (3.6 Å) |
Wang C, Kassem S, Rocha REO, Sun P, Nguyen TT, Kloehn
J, Liu X, Brusini L, Bonavoglia A, Barua S, Boissier F,
Lucia Del Cistia M, Peng H, Tang X, Xie F, Wang Z, Vadas
O, Suo X, Hashem Y, Soldati-Favre D, Jia Y |
(2024) "Apicomplexan
mitoribosome from highly fragmented rRNAs to a
functional machine." Nat Commun,
15, 10689. doi: 10.1038/s41467-024-55033-z.
|
Ssu(head) structure derived from the ssu sample of the
mitoribosome from t. gondii. . SNAP output
|
|
9fib
|
translation |
cryo-EM (2.3 Å) |
Safdari HA, Morici M, Sanchez-Castro A, Dallape A,
Paternoga H, Giuliodori AM, Fabbretti A, Milon P, Wilson
DN |
(2025) "The
translation inhibitors kasugamycin, edeine and GE81112
target distinct steps during 30S initiation complex
formation." Nat Commun,
16, 2470. doi: 10.1038/s41467-025-57731-8.
|
Structure of 30s-if1-if3-mrna-ge81112a complex .
SNAP output
|
|
9fmd
|
splicing |
cryo-EM (3.3 Å) |
Vorlander MK, Rothe P, Kleifeld J, Cormack ED, Veleti
L, Riabov-Bassat D, Fin L, Phillips AW, Cochella L,
Plaschka C |
(2024) "Mechanism
for the initiation of spliceosome disassembly."
Nature, 632, 443-450. doi:
10.1038/s41586-024-07741-1.
|
Integrative model of the human post-catalytic
spliceosome (p-complex) . SNAP output
|
|
9fny
|
translation |
cryo-EM (3.2 Å) |
Hassan AH, Pinkas M, Yaeshima C, Ishino S, Uchiumi T,
Ito K, Demo G |
(2025) "Novel
archaeal ribosome dimerization factor facilitating
unique 30S-30S dimerization." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1324.
|
Pf30s-pf30s dimer mediated by ardf from p. furiosus
(structure i) . SNAP
output
|
|
9fnz
|
translation |
cryo-EM (3.2 Å) |
Hassan AH, Pinkas M, Yaeshima C, Ishino S, Uchiumi T,
Ito K, Demo G |
(2025) "Novel
archaeal ribosome dimerization factor facilitating
unique 30S-30S dimerization." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1324.
|
Pf30s-pf30s dimer mediated by ardf from p. furiosus
(structure ii) . SNAP
output
|
|
9fo0
|
translation |
cryo-EM (3.4 Å) |
Hassan AH, Pinkas M, Yaeshima C, Ishino S, Uchiumi T,
Ito K, Demo G |
(2025) "Novel
archaeal ribosome dimerization factor facilitating
unique 30S-30S dimerization." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1324.
|
Pf30s ribosomal subunit - control . SNAP output
|
|
9fpy
|
transcription |
cryo-EM (2.4 Å) |
Grimm C, Bartuli J, Fischer U |
"Structure of the complete Vaccinia DNA-dependent RNA
polymerase complex at 2.65A resolution." |
Structure of the complete vaccinia DNA-dependent RNA
polymerase complex assembly intermediate 3 . SNAP output
|
|
9fpz
|
translation |
cryo-EM (2.69 Å) |
Klein M, Wild K, Sinning I |
(2024) "Multi-protein
assemblies orchestrate co-translational enzymatic
processing on the human ribosome." Nat
Commun, 15, 7681. doi: 10.1038/s41467-024-51964-9.
|
Human nata-map2 80s ribosome complex . SNAP output
|
|
9fq0
|
translation |
cryo-EM (4.67 Å) |
Klein M, Wild K, Sinning I |
(2024) "Multi-protein
assemblies orchestrate co-translational enzymatic
processing on the human ribosome." Nat
Commun, 15, 7681. doi: 10.1038/s41467-024-51964-9.
|
Human nata-nac-map1 80s ribosome complex . SNAP output
|
|
9fq6
|
transcription |
cryo-EM (2.5 Å) |
Grimm C, Bartuli J, Fischer U |
"Structure of the complete Vaccinia DNA-dependent RNA
polymerase complex assembly intermediate 4." |
Structure of the complete vaccinia DNA-dependent RNA
polymerase complex assembly intermediate 4 . SNAP output
|
|
9fra
|
translation |
cryo-EM (2.8 Å) |
Bourgeois G, Coureux PD, Lazennec-Schurdevin C, Madru
C, Gaillard T, Duchateau M, Chamot-Rooke J, Bourcier S,
Mechulam Y, Schmitt E |
(2025) "Structures
of Saccharolobus solfataricus initiation complexes with
leaderless mRNAs highlight archaeal features and
eukaryotic proximity." Nat Commun,
16, 348. doi: 10.1038/s41467-024-55718-5.
|
cryo-EM structure of saccharolobus solfataricus 30s
initiation complex bound to ss-map leaderless mrna .
SNAP output
|
|
9frk
|
translation |
cryo-EM (3.0 Å) |
Bourgeois G, Coureux PD, Lazennec-Schurdevin C, Madru
C, Gaillard T, Duchateau M, Chamot-Rooke J, Bourcier S,
Mechulam Y, Schmitt E |
(2025) "Structures
of Saccharolobus solfataricus initiation complexes with
leaderless mRNAs highlight archaeal features and
eukaryotic proximity." Nat Commun,
16, 348. doi: 10.1038/s41467-024-55718-5.
|
cryo-EM structure of saccharolobus solfataricus 30s
initiation complex bound to sd mrna . SNAP output
|
|
9frl
|
translation |
cryo-EM (2.97 Å) |
Bourgeois G, Coureux PD, Lazennec-Schurdevin C, Madru
C, Gaillard T, Duchateau M, Chamot-Rooke J, Bourcier S,
Mechulam Y, Schmitt E |
(2025) "Structures
of Saccharolobus solfataricus initiation complexes with
leaderless mRNAs highlight archaeal features and
eukaryotic proximity." Nat Commun,
16, 348. doi: 10.1038/s41467-024-55718-5.
|
cryo-EM structure of saccharolobus solfataricus 30s
initiation complex bound to sd mrna with h44 in up
position . SNAP
output
|
|
9fs6
|
translation |
cryo-EM (2.9 Å) |
Bourgeois G, Coureux PD, Lazennec-Schurdevin C, Madru
C, Gaillard T, Duchateau M, Chamot-Rooke J, Bourcier S,
Mechulam Y, Schmitt E |
(2025) "Structures
of Saccharolobus solfataricus initiation complexes with
leaderless mRNAs highlight archaeal features and
eukaryotic proximity." Nat Commun,
16, 348. doi: 10.1038/s41467-024-55718-5.
|
cryo-EM structure of saccharolobus solfataricus 30s
initiation complex bound to ss-aif2beta leaderless mrna
with h44 in up position . SNAP output
|
|
9fs8
|
translation |
cryo-EM (3.7 Å) |
Bourgeois G, Coureux PD, Lazennec-Schurdevin C, Madru
C, Gaillard T, Duchateau M, Chamot-Rooke J, Bourcier S,
Mechulam Y, Schmitt E |
(2025) "Structures
of Saccharolobus solfataricus initiation complexes with
leaderless mRNAs highlight archaeal features and
eukaryotic proximity." Nat Commun,
16, 348. doi: 10.1038/s41467-024-55718-5.
|
cryo-EM structure of saccharolobus solfataricus 30s
initiation complex bound to ss-aef1a-like mrna .
SNAP output
|
|
9fsf
|
translation |
cryo-EM (2.8 Å) |
Bourgeois G, Coureux PD, Lazennec-Schurdevin C, Madru
C, Gaillard T, Duchateau M, Chamot-Rooke J, Bourcier S,
Mechulam Y, Schmitt E |
(2025) "Structures
of Saccharolobus solfataricus initiation complexes with
leaderless mRNAs highlight archaeal features and
eukaryotic proximity." Nat Commun,
16, 348. doi: 10.1038/s41467-024-55718-5.
|
cryo-EM structure of saccharolobus solfataricus 30s
initiation complex bound to ss-map leaderless mrna with
h44 in up position . SNAP output
|
|
9fvd
|
viral protein |
cryo-EM (3.2 Å) |
Zinzula L, Beck F, Camasta M, Bohn S, Liu C, Morado
D, Bracher A, Plitzko JM, Baumeister W |
(2024) "Cryo-EM
structure of single-layered nucleoprotein-RNA complex
from Marburg virus." Nat Commun,
15, 10307. doi: 10.1038/s41467-024-54431-7.
|
cryo-EM structure of single-layered nucleoprotein-RNA
helical assembly from marburg virus, trimeric repeat
unit . SNAP output
|
|
9fy0
|
translation |
cryo-EM (2.9 Å) |
Bourgeois G, Coureux PD, Lazennec-Schurdevin C, Madru
C, Gaillard T, Duchateau M, Chamot-Rooke J, Bourcier S,
Mechulam Y, Schmitt E |
(2025) "Structures
of Saccharolobus solfataricus initiation complexes with
leaderless mRNAs highlight archaeal features and
eukaryotic proximity." Nat Commun,
16, 348. doi: 10.1038/s41467-024-55718-5.
|
cryo-EM structure of saccharolobus solfataricus 30s
initiation complex bound to ss-aif2beta leaderless mrna
. SNAP output
|
|
9g06
|
translation |
cryo-EM (2.85 Å) |
Safdari HA, Morici M, Sanchez-Castro A, Dallape A,
Paternoga H, Giuliodori AM, Fabbretti A, Milon P, Wilson
DN |
(2025) "The
translation inhibitors kasugamycin, edeine and GE81112
target distinct steps during 30S initiation complex
formation." Nat Commun,
16, 2470. doi: 10.1038/s41467-025-57731-8.
|
Structure of 30s-if1-if3-mrna-fmet-trna-ge81112a
complex . SNAP
output
|
|
9g1z
|
ribosome |
cryo-EM (3.1 Å) |
Kolosova O, Zgadzay Y, Stetsenko A, Sukhinina AP,
Atamas A, Validov S, Rogachev A, Usachev K, Jenner L,
Dmitriev SE, Yusupova G, Guskov A, Yusupov M |
(2025) "Mechanism
of read-through enhancement by aminoglycosides and
mefloquine." Proc.Natl.Acad.Sci.USA,
122, e2420261122. doi: 10.1073/pnas.2420261122.
|
Structure of candida albicans 80s ribosome in complex
with mefloquine (non-rotated state) . SNAP output
|
|
9g25
|
ribosome |
cryo-EM (2.89 Å) |
Fischer P, Thoms M, Lau B, Denk T, Kuvshinova M,
Berninghausen O, Flemming D, Hurt E, Beckmann R |
(2025) "H/ACA
snR30 snoRNP guides independent 18S rRNA subdomain
formation." Nat Commun,
16, 4720. doi: 10.1038/s41467-025-59656-8.
|
Snr30 snornp - state 1 - utp23-krr1-deltac3 . SNAP output
|
|
9g28
|
ribosome |
cryo-EM (3.18 Å) |
Fischer P, Thoms M, Lau B, Denk T, Kuvshinova M,
Berninghausen O, Flemming D, Hurt E, Beckmann R |
(2025) "H/ACA
snR30 snoRNP guides independent 18S rRNA subdomain
formation." Nat Commun,
16, 4720. doi: 10.1038/s41467-025-59656-8.
|
Snr30 snornp - state 2 - utp23-krr1-deltac3 . SNAP output
|
|
9g30
|
ribosome |
cryo-EM (2.35 Å) |
Kolosova O, Zgadzay Y, Stetsenko A, Sukhinina AP,
Atamas A, Validov S, Rogachev A, Usachev K, Jenner L,
Dmitriev SE, Yusupova G, Guskov A, Yusupov M |
(2025) "Mechanism
of read-through enhancement by aminoglycosides and
mefloquine." Proc.Natl.Acad.Sci.USA,
122, e2420261122. doi: 10.1073/pnas.2420261122.
|
The structure of the candida albicans ribosome with
trna-fmet, mrna, and compounds (gen and mfq) shows
strong density for the a site trna . SNAP output
|
|
9g33
|
ribosome |
cryo-EM (3.05 Å) |
Fischer P, Thoms M, Lau B, Denk T, Kuvshinova M,
Berninghausen O, Flemming D, Hurt E, Beckmann R |
(2025) "H/ACA
snR30 snoRNP guides independent 18S rRNA subdomain
formation." Nat Commun,
16, 4720. doi: 10.1038/s41467-025-59656-8.
|
Stalled 90s - utp23-krr1-deltac3 . SNAP output
|
|
9g5b
|
ribosome |
cryo-EM (3.2 Å) |
Heinrichs M, Finke AF, Aibara S, Krempler A,
Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein
R |
(2025) "Coupling
of ribosome biogenesis and translation initiation in
human mitochondria." Nat Commun,
16, 3641. doi: 10.1038/s41467-025-58827-x.
|
Assembly intermediate of human mitochondrial ribosome
small subunit (state a) . SNAP output
|
|
9g5c
|
ribosome |
cryo-EM (3.0 Å) |
Heinrichs M, Finke AF, Aibara S, Krempler A,
Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein
R |
(2025) "Coupling
of ribosome biogenesis and translation initiation in
human mitochondria." Nat Commun,
16, 3641. doi: 10.1038/s41467-025-58827-x.
|
Assembly intermediate of human mitochondrial ribosome
small subunit (state b) . SNAP output
|
|
9g5d
|
ribosome |
cryo-EM (3.0 Å) |
Heinrichs M, Finke AF, Aibara S, Krempler A,
Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein
R |
(2025) "Coupling
of ribosome biogenesis and translation initiation in
human mitochondria." Nat Commun,
16, 3641. doi: 10.1038/s41467-025-58827-x.
|
Assembly intermediate of human mitochondrial ribosome
small subunit (state c) . SNAP output
|
|
9g5e
|
ribosome |
cryo-EM (3.2 Å) |
Heinrichs M, Finke AF, Aibara S, Krempler A,
Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein
R |
(2025) "Coupling
of ribosome biogenesis and translation initiation in
human mitochondria." Nat Commun,
16, 3641. doi: 10.1038/s41467-025-58827-x.
|
Translation-initiation state of human mitochondrial
ribosome small subunit (state f) . SNAP output
|
|
9g6j
|
ribosome |
cryo-EM (2.15 Å) |
Kolosova O, Zgadzay Y, Stetsenko A, Sukhinina AP,
Atamas A, Validov S, Rogachev A, Usachev K, Jenner L,
Dmitriev SE, Yusupova G, Guskov A, Yusupov M |
(2025) "Mechanism
of read-through enhancement by aminoglycosides and
mefloquine." Proc.Natl.Acad.Sci.USA,
122, e2420261122. doi: 10.1073/pnas.2420261122.
|
The structure of the candida albicans ribosome with
trna-fmet, mrna, and compounds (gen and mfq) with
strong density for the p-site trna . SNAP output
|
|
9g8n
|
ribosome |
cryo-EM (3.7 Å) |
Kogel A, Keidel A, Loukeri MJ, Kuhn CC, Langer LM,
Schafer IB, Conti E |
(2024) "Structural
basis of mRNA decay by the human exosome-ribosome
supercomplex." Nature,
635, 237-242. doi: 10.1038/s41586-024-08015-6.
|
80s-bound human ski2-exosome complex . SNAP output
|
|
9g8p
|
ribosome |
cryo-EM (7.0 Å) |
Kogel A, Keidel A, Loukeri MJ, Kuhn CC, Langer LM,
Schafer IB, Conti E |
(2024) "Structural
basis of mRNA decay by the human exosome-ribosome
supercomplex." Nature,
635, 237-242. doi: 10.1038/s41586-024-08015-6.
|
40s-bound human ski2-exosome complex . SNAP output
|
|
9g9a
|
RNA binding protein |
cryo-EM (2.83 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus csm-crrna
(3.2 complex) . SNAP
output
|
|
9g9b
|
RNA binding protein |
cryo-EM (3.07 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus csm-crrna
(4.3) complex . SNAP
output
|
|
9g9c
|
RNA binding protein |
cryo-EM (2.72 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus csm-crrna-ctr
(3.2) complex . SNAP
output
|
|
9g9d
|
RNA binding protein |
cryo-EM (2.9 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus csm-crrna-ctr
(4.3) complex . SNAP
output
|
|
9g9e
|
RNA binding protein |
cryo-EM (2.87 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus csm-crrna
complex bound to ampnpp . SNAP output
|
|
9g9f
|
RNA binding protein |
cryo-EM (2.93 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus csm-crrna-ctr
complex bound to ampnpp . SNAP output
|
|
9g9g
|
RNA binding protein |
cryo-EM (3.38 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus
csm-crrna-ctr1 complex (4.3) bound to ampnpp . SNAP output
|
|
9g9h
|
RNA binding protein |
cryo-EM (2.99 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus
csm-crrna-ctr1 complex bound to pnppa3 and ampnpp .
SNAP output
|
|
9g9i
|
RNA binding protein |
cryo-EM (3.31 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus
csm-crrna-ctr2 complex bound to pnppa3 and ampnpp .
SNAP output
|
|
9g9j
|
RNA binding protein |
cryo-EM (3.05 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus csm-crrna
complex bound to pnppa3 and ampnpp . SNAP output
|
|
9g9k
|
RNA binding protein |
cryo-EM (3.34 Å) |
Jungfer K, Moravcik S, Garcia-Doval C, Knorlein A,
Hall J, Jinek M |
(2025) "Mechanistic
determinants and dynamics of cA6 synthesis in type III
CRISPR-Cas effector complexes." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1277.
|
Cryoem structure of enterococcus italicus
csm-crrna-ctr2 complex (4.3) bound to ampnpp . SNAP output
|
|
9gan
|
viral protein |
cryo-EM (3.32 Å) |
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ,
Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T |
(2025) "Influenza
a virus antiparallel helical nucleocapsid-like
pseudo-atomic structure." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1211.
|
Cryoem structure of influenza a rnp-like particle
single-stranded assembled with a 12-mer RNA. . SNAP output
|
|
9gap
|
viral protein |
cryo-EM (4.0 Å) |
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ,
Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T |
(2025) "Influenza
a virus antiparallel helical nucleocapsid-like
pseudo-atomic structure." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1211.
|
Cryoem structure of influenza a rnp-like particle
double-stranded assembled with a 12-mer RNA. . SNAP output
|
|
9gaq
|
viral protein |
cryo-EM (3.6 Å) |
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ,
Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T |
(2025) "Influenza
a virus antiparallel helical nucleocapsid-like
pseudo-atomic structure." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1211.
|
Cryoem structure of influenza a rnp-like particle
double-stranded assembled with a 14-mer RNA. . SNAP output
|
|
9gas
|
viral protein |
cryo-EM (3.08 Å) |
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ,
Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T |
(2025) "Influenza
a virus antiparallel helical nucleocapsid-like
pseudo-atomic structure." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1211.
|
Focused reconstruction on strand 2 of the influenza a
rnp-like particle double-stranded assembled with a
18-mer RNA. . SNAP
output
|
|
9gat
|
viral protein |
cryo-EM (3.2 Å) |
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ,
Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T |
(2025) "Influenza
a virus antiparallel helical nucleocapsid-like
pseudo-atomic structure." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1211.
|
Cryoem structure of the antiparallel double-stranded
influenza a rnp-like particle with a 18-mer RNA. .
SNAP output
|
|
9gav
|
viral protein |
cryo-EM (3.04 Å) |
Chenavier F, Zarkadas E, Freslon LL, Stelfox AJ,
Schoehn G, Ruigrok RWH, Ballandras-Colas A, Crepin T |
(2025) "Influenza
a virus antiparallel helical nucleocapsid-like
pseudo-atomic structure." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkae1211.
|
Focused reconstruction on strand 1 of the influenza a
rnp-like particle double-stranded assembled with a
18-mer RNA. . SNAP
output
|
|
9gbw
|
splicing |
cryo-EM (3.5 Å) |
Zhao J, Peter D, Brandina I, Liu X, Galej WP |
(2025) "Structural
basis of 5' splice site recognition by the minor
spliceosome." Mol.Cell,
85, 652. doi: 10.1016/j.molcel.2024.12.017.
|
Overall structure of the substrate-bound u11 snrnp .
SNAP output
|
|
9gbz
|
splicing |
cryo-EM (3.4 Å) |
Zhao J, Peter D, Brandina I, Liu X, Galej WP |
(2025) "Structural
basis of 5' splice site recognition by the minor
spliceosome." Mol.Cell,
85, 652. doi: 10.1016/j.molcel.2024.12.017.
|
5'-lobe of the substrate-bound u11 snrnp . SNAP output
|
|
9gc0
|
splicing |
cryo-EM (3.2 Å) |
Zhao J, Peter D, Brandina I, Liu X, Galej WP |
(2025) "Structural
basis of 5' splice site recognition by the minor
spliceosome." Mol.Cell,
85, 652. doi: 10.1016/j.molcel.2024.12.017.
|
3'-lobe of the substrate-bound u11 snrnp . SNAP output
|
|
9gch
|
RNA binding protein |
cryo-EM (1.9 Å) |
Valentin Gese G, Hallberg BM |
(2024) "Structural
basis of 3'-tRNA maturation by the human mitochondrial
RNase Z complex." Embo J.,
43, 6573-6590. doi: 10.1038/s44318-024-00297-w.
|
Human mitochondrial rnase z with trna-his-cca,
sdr5c1-trmt10c focus . SNAP output
|
|
9gcl
|
splicing |
cryo-EM (3.0 Å) |
Zhao J, Peter D, Brandina I, Liu X, Galej WP |
(2025) "Structural
basis of 5' splice site recognition by the minor
spliceosome." Mol.Cell,
85, 652. doi: 10.1016/j.molcel.2024.12.017.
|
Structure of the u11 snrnp c-lobe . SNAP output
|
|
9gcm
|
splicing |
cryo-EM (3.1 Å) |
Zhao J, Peter D, Brandina I, Liu X, Galej WP |
(2025) "Structural
basis of 5' splice site recognition by the minor
spliceosome." Mol.Cell,
85, 652. doi: 10.1016/j.molcel.2024.12.017.
|
Structure of the u11 snrnp core . SNAP output
|
|
9gft
|
ribosome |
cryo-EM (3.1 Å) |
Campbell A, Esser HF, Burroughs AM, Berninghausen O,
Aravind L, Becker T, Green R, Beckmann R, Buskirk AR |
(2025) "The RNA
helicase HrpA rescues collided ribosomes in E.
coli." Mol.Cell, 85,
999-1007.e7. doi: 10.1016/j.molcel.2025.01.018.
|
Structure of the hrpa-bound e. coli disome, class i .
SNAP output
|
|
9ggr
|
ribosome |
cryo-EM (3.2 Å) |
Campbell A, Esser HF, Burroughs AM, Berninghausen O,
Aravind L, Becker T, Green R, Beckmann R, Buskirk AR |
(2025) "The RNA
helicase HrpA rescues collided ribosomes in E.
coli." Mol.Cell, 85,
999-1007.e7. doi: 10.1016/j.molcel.2025.01.018.
|
Structure of the hrpa-bound e. coli disome, class ii .
SNAP output
|
|
9gha
|
ribosome |
cryo-EM (2.24 Å) |
Gonzalez-Lopez A, Ge X, Larsson DSD, Sihlbom Wallem
C, Sanyal S, Selmer M |
(2025) "Structural
mechanism of FusB-mediated rescue from fusidic acid
inhibition of protein synthesis." Nat
Commun, 16, 3693. doi: 10.1038/s41467-025-58902-3.
|
Fusidic acid-locked escherichia coli 70s ribosome with
staphylococcus aureus ef-g and a trna in pe-e chimeric
state (chi) . SNAP
output
|
|
9ghb
|
ribosome |
cryo-EM (2.21 Å) |
Gonzalez-Lopez A, Ge X, Larsson DSD, Sihlbom Wallem
C, Sanyal S, Selmer M |
(2025) "Structural
mechanism of FusB-mediated rescue from fusidic acid
inhibition of protein synthesis." Nat
Commun, 16, 3693. doi: 10.1038/s41467-025-58902-3.
|
Fusidic acid-locked escherichia coli 70s ribosome with
staphylococcus aureus ef-g in post-translocational
state (post) . SNAP
output
|
|
9ghc
|
ribosome |
cryo-EM (2.79 Å) |
Gonzalez-Lopez A, Ge X, Larsson DSD, Sihlbom Wallem
C, Sanyal S, Selmer M |
(2025) "Structural
mechanism of FusB-mediated rescue from fusidic acid
inhibition of protein synthesis." Nat
Commun, 16, 3693. doi: 10.1038/s41467-025-58902-3.
|
Pre-release fusidic acid-locked escherichia coli 70s
ribosome with staphylococus aureus ef-g and fusb
(fusb-ef-g-70s) . SNAP
output
|
|
9ghd
|
ribosome |
cryo-EM (2.41 Å) |
Gonzalez-Lopez A, Ge X, Larsson DSD, Sihlbom Wallem
C, Sanyal S, Selmer M |
(2025) "Structural
mechanism of FusB-mediated rescue from fusidic acid
inhibition of protein synthesis." Nat
Commun, 16, 3693. doi: 10.1038/s41467-025-58902-3.
|
Escherichia coli 70s ribosome in complex with
staphylococcus aureus fusb-ef-g (fusb-ef-g-70s*) .
SNAP output
|
|
9ghe
|
ribosome |
cryo-EM (1.87 Å) |
Gonzalez-Lopez A, Ge X, Larsson DSD, Sihlbom Wallem
C, Sanyal S, Selmer M |
(2025) "Structural
mechanism of FusB-mediated rescue from fusidic acid
inhibition of protein synthesis." Nat
Commun, 16, 3693. doi: 10.1038/s41467-025-58902-3.
|
Staphylococcus aureus fusb bound to the small subunit
of the escherichia coli 70s ribosome (fusb-70s:ssu) .
SNAP output
|
|
9ghf
|
ribosome |
cryo-EM (2.4 Å) |
Gonzalez-Lopez A, Ge X, Larsson DSD, Sihlbom Wallem
C, Sanyal S, Selmer M |
(2025) "Structural
mechanism of FusB-mediated rescue from fusidic acid
inhibition of protein synthesis." Nat
Commun, 16, 3693. doi: 10.1038/s41467-025-58902-3.
|
Staphylococcus aureus fusb bound to the large subunit
of the escherichia coli 70s ribosome (fusb-70s:lsu) .
SNAP output
|
|
9ghg
|
ribosome |
cryo-EM (2.22 Å) |
Gonzalez-Lopez A, Ge X, Larsson DSD, Sihlbom Wallem
C, Sanyal S, Selmer M |
(2025) "Structural
mechanism of FusB-mediated rescue from fusidic acid
inhibition of protein synthesis." Nat
Commun, 16, 3693. doi: 10.1038/s41467-025-58902-3.
|
Staphylococcus aureus fusb bound to the small subunit
of the s. aureus 70s ribosome (fusb-sa70s:ssu) .
SNAP output
|
|
9ghh
|
ribosome |
cryo-EM (2.7 Å) |
Gonzalez-Lopez A, Ge X, Larsson DSD, Sihlbom Wallem
C, Sanyal S, Selmer M |
(2025) "Structural
mechanism of FusB-mediated rescue from fusidic acid
inhibition of protein synthesis." Nat
Commun, 16, 3693. doi: 10.1038/s41467-025-58902-3.
|
Staphylococcus aureus fusb bound to the large subunit
of the s. aureus 70s ribosome (fusb-sa70s:lsu) .
SNAP output
|
|
9gju
|
viral protein |
cryo-EM (2.8 Å) |
Sala FA, Ditter K, Dybkov O, Urlaub H, Hillen HS |
(2025) "Structural
basis of Nipah virus RNA synthesis." Nat
Commun, 16, 2261. doi: 10.1038/s41467-025-57219-5.
|
Structure of replicating nipah virus RNA polymerase
complex - RNA-bound state . SNAP output
|
|
9gmo
|
ribosome |
cryo-EM (2.59 Å) |
Akers J, Bothe A, Suh H, Jung C, Stolp Z, Ghosh T,
Yan L, Wang Y, Grismer T, Reyes A, Hu T, Xu S, Ban N,
Kostova K |
(2024) "ZNF574
is a Quality Control Factor For Defective Ribosome
Biogenesis Intermediates." Biorxiv. doi:
10.1101/2024.04.26.591394.
|
Eif6-bound pre-60s large ribosomal subunit
incorporating mutant ul16 . SNAP output
|
|
9gms
|
RNA |
cryo-EM (1.98 Å) |
Griesser T, Wang R, Angona IP, Rogenmoser J, Obrist
J, Schneider G, Sander P |
(2025) "Selective
inhibition of Mycobacterium tuberculosis GpsI unveils a
novel strategy to target the RNA metabolism."
Nucleic Acids Res., 53. doi:
10.1093/nar/gkaf529.
|
Mtb pnpase rv2783c . SNAP output
|
|
9gmt
|
RNA |
cryo-EM (1.93 Å) |
Griesser T, Wang R, Angona IP, Rogenmoser J, Obrist
J, Schneider G, Sander P |
(2025) "Selective
inhibition of Mycobacterium tuberculosis GpsI unveils a
novel strategy to target the RNA metabolism."
Nucleic Acids Res., 53. doi:
10.1093/nar/gkaf529.
|
Mtb pnpase rv2783c mutant l328f . SNAP output
|
|
9gmw
|
hydrolase |
cryo-EM (3.0 Å) |
Kugler M, Metzner FJ, Witte G, Hopfner KP, Lammens
K |
(2024) "Phosphorylation-mediated
conformational change regulates human SLFN11."
Nat Commun, 15, 10500. doi:
10.1038/s41467-024-54833-7.
|
Slfn11 wt dimer bound to trna-leu-taa (pre-cleavage
state) . SNAP output
|
|
9gmx
|
hydrolase |
cryo-EM (2.82 Å) |
Kugler M, Metzner FJ, Witte G, Hopfner KP, Lammens
K |
(2024) "Phosphorylation-mediated
conformational change regulates human SLFN11."
Nat Commun, 15, 10500. doi:
10.1038/s41467-024-54833-7.
|
Slfn11 wt dimer bound to trna-leu-taa (post-cleavage
state) . SNAP output
|
|
9gr1
|
gene regulation |
cryo-EM (3.17 Å) |
Webster MW, Chauvier A, Rahil H, Graziadei A, Charles
K, Miropolskaya N, Takacs M, Saint-Andre C, Rappsilber J,
Walter NG, Weixlbaumer A |
(2024) "Molecular
basis of mRNA delivery to the bacterial ribosome."
Science, 386, eado8476. doi:
10.1126/science.ado8476.
|
E. coli 70s-tec complex in delivery state . SNAP output
|
|
9gu5
|
hydrolase |
X-ray (2.9 Å) |
McQuail J, Krepl M, Katsuya-Gaviria K, Tabib-Salazar
A, Burchell L, Bischler T, Grafenhan T, Brear P, Sponer
J, Luisi BF, Wigneshweraraj S |
(2025) "Transcriptome-scale
analysis uncovers conserved residues in the hydrophobic
core of the bacterial RNA chaperone Hfq required for
small regulatory RNA stability." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkaf019.
|
Crystal structure of hfq v22a . SNAP output
|
|
9gup
|
ribosome |
cryo-EM (2.8 Å) |
Webster MW, Chauvier A, Rahil H, Graziadei A, Charles
K, Miropolskaya N, Takacs M, Saint-Andre C, Rappsilber J,
Walter NG, Weixlbaumer A |
(2024) "Molecular
basis of mRNA delivery to the bacterial ribosome."
Science, 386, eado8476. doi:
10.1126/science.ado8476.
|
30s mrna delivery complex (open head) . SNAP output
|
|
9guq
|
ribosome |
cryo-EM (3.1 Å) |
Webster MW, Chauvier A, Rahil H, Graziadei A, Charles
K, Miropolskaya N, Takacs M, Saint-Andre C, Rappsilber J,
Walter NG, Weixlbaumer A |
(2024) "Molecular
basis of mRNA delivery to the bacterial ribosome."
Science, 386, eado8476. doi:
10.1126/science.ado8476.
|
30s pic (pre-initiation complex) . SNAP output
|
|
9gus
|
ribosome |
cryo-EM (3.5 Å) |
Webster MW, Chauvier A, Rahil H, Graziadei A, Charles
K, Miropolskaya N, Takacs M, Saint-Andre C, Rappsilber J,
Walter NG, Weixlbaumer A |
(2024) "Molecular
basis of mRNA delivery to the bacterial ribosome."
Science, 386, eado8476. doi:
10.1126/science.ado8476.
|
30s mrna delivery complex tec resolved (30s only) .
SNAP output
|
|
9guu
|
ribosome |
cryo-EM (2.5 Å) |
Webster MW, Chauvier A, Rahil H, Graziadei A, Charles
K, Miropolskaya N, Takacs M, Saint-Andre C, Rappsilber J,
Walter NG, Weixlbaumer A |
(2024) "Molecular
basis of mRNA delivery to the bacterial ribosome."
Science, 386, eado8476. doi:
10.1126/science.ado8476.
|
30s mrna delivery complex (consensus) . SNAP output
|
|
9guv
|
ribosome |
cryo-EM (3.0 Å) |
Webster MW, Chauvier A, Rahil H, Graziadei A, Charles
K, Miropolskaya N, Takacs M, Saint-Andre C, Rappsilber J,
Walter NG, Weixlbaumer A |
(2024) "Molecular
basis of mRNA delivery to the bacterial ribosome."
Science, 386, eado8476. doi:
10.1126/science.ado8476.
|
30s mrna delivery complex (closed-head) . SNAP output
|
|
9gxx
|
ribosome |
cryo-EM (2.61 Å) |
Krishnaswamy S, Akbar S, Larsson DSD, Chen Y, Selmer
M |
(2025) "Doublet
decoding of tRNA Ser3 demonstrates plasticity of
ribosomal decoding center." Nat Commun,
16, 5402. doi: 10.1038/s41467-025-61016-5.
|
70s ribosome with doublet-decoding trnaser3 bound to
a-site gca codon . SNAP
output
|
|
9gy4
|
ribosome |
cryo-EM (3.0 Å) |
Penchev I, Gumbin S, Scavone F, Berninghausen O,
Becker T, Kopito R, Beckmann R |
(2025) "UFMylation
orchestrates spatiotemporal coordination of RQC at the
ER." Sci Adv, 11,
eadv0435. doi: 10.1126/sciadv.adv0435.
|
60s ribosomal subunit in complex with e3-ufm1 ligase
and rqc machinery components nemf and ltn1 (composite
map) . SNAP output
|
|
9h0l
|
ribosome |
cryo-EM (2.49 Å) |
Krishnaswamy S, Akbar S, Larsson DSD, Chen Y, Selmer
M |
(2025) "Doublet
decoding of tRNA Ser3 demonstrates plasticity of
ribosomal decoding center." Nat Commun,
16, 5402. doi: 10.1038/s41467-025-61016-5.
|
70s ribosome with cognate trnaser3 bound to a-site agc
codon . SNAP output
|
|
9h1k
|
transferase |
X-ray (1.89 Å) |
Tanouti Y, Roovers M, Wolff P, Lechner A, Van Elder
D, Feller A, Soin R, Gueydan C, Kruys V, Droogmans L,
Labar G |
(2025) "Structural
insight into the novel Thermus thermophilus SPOUT
methyltransferase RlmR catalysing Um2552 formation in
the 23S rRNA A-loop: a case of convergent
evolution." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf432.
|
Rlmr 23s rrna methyltransferase from thermus
thermophilus in complex with rrna and
s-adenosyl-l-homocysteine (sah) . SNAP output
|
|
9h3k
|
ribosome |
cryo-EM (6.62 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor d126_(l29)--(l22)- . SNAP output
|
|
9h3l
|
ribosome |
cryo-EM (5.84 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c_(l29)--(l22)- . SNAP output
|
|
9h3m
|
ribosome |
cryo-EM (4.41 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c_(l22)- . SNAP output
|
|
9h3n
|
ribosome |
cryo-EM (3.69 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c_(l22)-~h61 . SNAP output
|
|
9h3o
|
ribosome |
cryo-EM (4.54 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c_(l22)-_gac . SNAP output
|
|
9h3p
|
ribosome |
cryo-EM (7.06 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c-cp_(l22)- . SNAP output
|
|
9h3q
|
ribosome |
cryo-EM (4.02 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c-cp_yjga_(l22)-~h61 . SNAP output
|
|
9h3r
|
ribosome |
cryo-EM (4.12 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c-cp_yjga_(l22)- . SNAP output
|
|
9h3s
|
ribosome |
cryo-EM (4.16 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c-cp_yjga_l22 . SNAP output
|
|
9h3t
|
ribosome |
cryo-EM (3.85 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c_l2 . SNAP output
|
|
9h3u
|
ribosome |
cryo-EM (3.47 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c_h68 . SNAP output
|
|
9h3v
|
ribosome |
cryo-EM (3.55 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c-cp_l2-l28 . SNAP output
|
|
9h3w
|
ribosome |
cryo-EM (5.38 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c-cp_h68 . SNAP output
|
|
9h3x
|
ribosome |
cryo-EM (4.12 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor c-cp_h68_l35 . SNAP output
|
|
9h3y
|
ribosome |
cryo-EM (3.09 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
50s subunit precursor 50s_(l16)- . SNAP output
|
|
9h3z
|
ribosome |
cryo-EM (2.98 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Mature 50s subunit . SNAP output
|
|
9h45
|
hydrolase |
X-ray (2.08 Å) |
McQuail J, Krepl M, Katsuya-Gaviria K, Tabib-Salazar
A, Burchell L, Bischler T, Grafenhan T, Brear P, Sponer
J, Luisi BF, Wigneshweraraj S |
(2025) "Transcriptome-scale
analysis uncovers conserved residues in the hydrophobic
core of the bacterial RNA chaperone Hfq required for
small regulatory RNA stability." Nucleic Acids
Res., 53. doi: 10.1093/nar/gkaf019.
|
Crystal structure of hfq v22a . SNAP output
|
|
9h90
|
ribosome |
cryo-EM (2.8 Å) |
Raulf K, Koller TO, Beckert B, Lepak A, Morici M,
Mardirossian M, Scocchi M, Bange G, Wilson DN |
(2025) "The
structure of the Vibrio natriegens 70S ribosome in
complex with the proline-rich antimicrobial peptide
Bac5(1-17)." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf324.
|
cryo-EM structure of the vibrio natrigens 30s ribosomal
subunit in complex with spectinomycin. . SNAP output
|
|
9h91
|
ribosome |
cryo-EM (2.7 Å) |
Raulf K, Koller TO, Beckert B, Lepak A, Morici M,
Mardirossian M, Scocchi M, Bange G, Wilson DN |
(2025) "The
structure of the Vibrio natriegens 70S ribosome in
complex with the proline-rich antimicrobial peptide
Bac5(1-17)." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf324.
|
cryo-EM structure of the vibrio natrigens 50s ribosomal
subunit in complex with the proline-rich antimicrobial
peptide bac5(1-17). . SNAP output
|
|
9ha1
|
ribosome |
cryo-EM (4.17 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Pooled 50s subunit c_(l22)- precursor states
supplemented with api137 - canonical pet exit api137 .
SNAP output
|
|
9ha2
|
ribosome |
cryo-EM (4.17 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Pooled 50s subunit c_(l22)- precursor states
supplemented with api137 - alternative pet exit api137
. SNAP output
|
|
9ha3
|
ribosome |
cryo-EM (3.62 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Pooled 50s subunit c_(l22)-~h61 precursor states
supplemented with api137 . SNAP output
|
|
9ha4
|
ribosome |
cryo-EM (4.26 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Pooled 50s subunit c-cp_(l22)- precursor states
supplemented with api137 . SNAP output
|
|
9ha5
|
ribosome |
cryo-EM (3.3 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Pooled 50s subunit c_l2 precursor states supplemented
with api137 . SNAP
output
|
|
9ha6
|
ribosome |
cryo-EM (3.08 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Mature 50s subunit supplemented with api137 . SNAP output
|
|
9ha7
|
ribosome |
cryo-EM (4.37 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Pooled 50s subunit c-cp_(l22)-~h61 precursor states
supplemented with api137 . SNAP output
|
|
9hai
|
ribosome |
cryo-EM (3.01 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Pooled 50s subunit c-cp_l2-l28 precursor states
supplemented with api137 . SNAP output
|
|
9hal
|
ribosome |
cryo-EM (4.49 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
Pooled 50s subunit d126_(l29)--(l22)- precursor states
supplemented with api137 . SNAP output
|
|
9ham
|
ribosome |
cryo-EM (5.06 Å) |
Lauer SM, Gasse J, Krizsan A, Reepmeyer M, Sprink T,
Nikolay R, Spahn CMT, Hoffmann R |
(2025) "The
proline-rich antimicrobial peptide Api137 disrupts
large ribosomal subunit assembly and induces
misfolding." Nat Commun,
16, 567. doi: 10.1038/s41467-025-55836-8.
|
C_(l29)--(l22)- precursor supplemented with api137 .
SNAP output
|
|
9hbr
|
RNA binding protein |
cryo-EM (2.9 Å) |
Arragain B, Pelosse M, Huard K, Cusack S |
(2025) "Structure
of the tilapia lake virus nucleoprotein bound to
RNA." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf112.
|
Tilv-np pentamer (pseudo-c5) (local refinement around 2
tilv-nps) . SNAP
output
|
|
9hbs
|
RNA binding protein |
cryo-EM (3.68 Å) |
Arragain B, Pelosse M, Huard K, Cusack S |
(2025) "Structure
of the tilapia lake virus nucleoprotein bound to
RNA." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf112.
|
Tilv-np tetramer (pseudo-c2) . SNAP output
|
|
9hbt
|
RNA binding protein |
cryo-EM (3.46 Å) |
Arragain B, Pelosse M, Huard K, Cusack S |
(2025) "Structure
of the tilapia lake virus nucleoprotein bound to
RNA." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf112.
|
Tilv-np pentamer (pseudo-c5) . SNAP output
|
|
9hbu
|
RNA binding protein |
cryo-EM (3.51 Å) |
Arragain B, Pelosse M, Huard K, Cusack S |
(2025) "Structure
of the tilapia lake virus nucleoprotein bound to
RNA." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf112.
|
Tilv-np tetramer (pseudo-c2) (local refinement around 2
tilv-nps) . SNAP
output
|
|
9hbv
|
RNA binding protein |
cryo-EM (3.38 Å) |
Arragain B, Pelosse M, Huard K, Cusack S |
(2025) "Structure
of the tilapia lake virus nucleoprotein bound to
RNA." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf112.
|
Tilv-np tetramer (pseudo-c4) (local refinement around 2
tilv-nps) . SNAP
output
|
|
9hbw
|
RNA binding protein |
cryo-EM (3.59 Å) |
Arragain B, Pelosse M, Huard K, Cusack S |
(2025) "Structure
of the tilapia lake virus nucleoprotein bound to
RNA." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf112.
|
Tilv-np tetramer (pseudo-c4) . SNAP output
|
|
9hbx
|
RNA binding protein |
cryo-EM (3.04 Å) |
Arragain B, Pelosse M, Huard K, Cusack S |
(2025) "Structure
of the tilapia lake virus nucleoprotein bound to
RNA." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf112.
|
Tilv-np hexamer (pseudo-c6) (local refinement around 2
tilv-nps) . SNAP
output
|
|
9hby
|
RNA binding protein |
cryo-EM (3.1 Å) |
Arragain B, Pelosse M, Huard K, Cusack S |
(2025) "Structure
of the tilapia lake virus nucleoprotein bound to
RNA." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf112.
|
Tilv-np hexamer (pseudo-c6) (local refinement around 3
tilv-nps) . SNAP
output
|
|
9hbz
|
RNA binding protein |
cryo-EM (3.49 Å) |
Arragain B, Pelosse M, Huard K, Cusack S |
(2025) "Structure
of the tilapia lake virus nucleoprotein bound to
RNA." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf112.
|
Tilv-np hexamer (pseudo-c6) . SNAP output
|
|
9hc4
|
ribosome |
cryo-EM (3.2 Å) |
Helena-Bueno K, Kopetschke S, Filbeck S, Chan LI,
Birsan S, Basle A, Hudson M, Pfeffer S, Hill CH, Melnikov
SV |
(2025) "Structurally
heterogeneous ribosomes cooperate in protein synthesis
in bacterial cells." Nat Commun,
16, 2751. doi: 10.1038/s41467-025-57955-8.
|
cryo-EM structure of p. urativorans 70s ribosome with 2
copies of bs20. . SNAP
output
|
|
9hcc
|
ribosome |
cryo-EM (5.67 Å) |
Glasgow RIC, Singh V, Pena-Perez L, Wilhalm A, Moedas
MF, Moore D, Rosenberger FA, Li X, Atanassov I, Saba M,
Cipullo M, Rorbach J, Wedell A, Freyer C, Amunts A,
Wredenberg A |
(2025) "The
mitochondrial methylation potential gates mitoribosome
assembly." Nat Commun,
16, 5388. doi: 10.1038/s41467-025-60977-x.
|
Mouse mitoribosome large subunit assembly intermediate
(without ul16m) bound to mrm3-dimer, ddx28 and the
malsu-l0r8f8-mt-acp complex, state a1 (samc knock-out)
. SNAP output
|
|
9hcd
|
ribosome |
cryo-EM (4.63 Å) |
Glasgow RIC, Singh V, Pena-Perez L, Wilhalm A, Moedas
MF, Moore D, Rosenberger FA, Li X, Atanassov I, Saba M,
Cipullo M, Rorbach J, Wedell A, Freyer C, Amunts A,
Wredenberg A |
(2025) "The
mitochondrial methylation potential gates mitoribosome
assembly." Nat Commun,
16, 5388. doi: 10.1038/s41467-025-60977-x.
|
Mouse mitoribosome large subunit assembly intermediate
(with ul16m) bound to mrm3-dimer, ddx28 and the
malsu-l0r8f8-mt-acp complex, state a2 (samc knock-out)
. SNAP output
|
|
9hce
|
ribosome |
cryo-EM (7.31 Å) |
Glasgow RIC, Singh V, Pena-Perez L, Wilhalm A, Moedas
MF, Moore D, Rosenberger FA, Li X, Atanassov I, Saba M,
Cipullo M, Rorbach J, Wedell A, Freyer C, Amunts A,
Wredenberg A |
(2025) "The
mitochondrial methylation potential gates mitoribosome
assembly." Nat Commun,
16, 5388. doi: 10.1038/s41467-025-60977-x.
|
Mouse mitoribosome large subunit assembly intermediate
(without ul16m) bound to mrm3 dimer and the
malsu-l0r8f8-mt-acp complex, state a3 (samc knock out)
. SNAP output
|
|
9hcf
|
ribosome |
cryo-EM (2.85 Å) |
Glasgow RIC, Singh V, Pena-Perez L, Wilhalm A, Moedas
MF, Moore D, Rosenberger FA, Li X, Atanassov I, Saba M,
Cipullo M, Rorbach J, Wedell A, Freyer C, Amunts A,
Wredenberg A |
(2025) "The
mitochondrial methylation potential gates mitoribosome
assembly." Nat Commun,
16, 5388. doi: 10.1038/s41467-025-60977-x.
|
Mouse mitoribosome large subunit assembly intermediate
bound to nsun4, metrf4, gtpbp7, gtpbp10 and the
malsu-l0r8f8-mtacp complex with ul16m, state b2 (samc
knock-out) . SNAP
output
|
|
9hcg
|
ribosome |
cryo-EM (2.91 Å) |
Glasgow RIC, Singh V, Pena-Perez L, Wilhalm A, Moedas
MF, Moore D, Rosenberger FA, Li X, Atanassov I, Saba M,
Cipullo M, Rorbach J, Wedell A, Freyer C, Amunts A,
Wredenberg A |
(2025) "The
mitochondrial methylation potential gates mitoribosome
assembly." Nat Commun,
16, 5388. doi: 10.1038/s41467-025-60977-x.
|
Mouse mitoribosome large subunit assembly intermediate
bound to nsun4, metrf4, mrm2, gtpbp7 and
malsu1-l0r8f8-mt-acp complex, state d (samc knock-out)
. SNAP output
|
|
9hch
|
ribosome |
cryo-EM (2.85 Å) |
Glasgow RIC, Singh V, Pena-Perez L, Wilhalm A, Moedas
MF, Moore D, Rosenberger FA, Li X, Atanassov I, Saba M,
Cipullo M, Rorbach J, Wedell A, Freyer C, Amunts A,
Wredenberg A |
(2025) "The
mitochondrial methylation potential gates mitoribosome
assembly." Nat Commun,
16, 5388. doi: 10.1038/s41467-025-60977-x.
|
Mouse mitoribosome large subunit assembly intermediate
bound to nsun4, metrf4, gtpbp7 and the
malsu1-l0r8f8-mt-acp complex, state c1 (samc knock-out)
. SNAP output
|
|
9hfm
|
ribosome |
cryo-EM (3.0 Å) |
Heinrichs M, Finke AF, Aibara S, Krempler A,
Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein
R |
(2025) "Coupling
of ribosome biogenesis and translation initiation in
human mitochondria." Nat Commun,
16, 3641. doi: 10.1038/s41467-025-58827-x.
|
Translation-initiation state of human mitochondrial
ribosome small subunit (state d) . SNAP output
|
|
9hfn
|
ribosome |
cryo-EM (3.3 Å) |
Heinrichs M, Finke AF, Aibara S, Krempler A,
Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein
R |
(2025) "Coupling
of ribosome biogenesis and translation initiation in
human mitochondria." Nat Commun,
16, 3641. doi: 10.1038/s41467-025-58827-x.
|
Translation-initiation state of human mitochondrial
ribosome small subunit (state e) . SNAP output
|
|
9hfo
|
ribosome |
cryo-EM (3.1 Å) |
Heinrichs M, Finke AF, Aibara S, Krempler A,
Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein
R |
(2025) "Coupling
of ribosome biogenesis and translation initiation in
human mitochondria." Nat Commun,
16, 3641. doi: 10.1038/s41467-025-58827-x.
|
Translation-initiation state of human mitochondrial
ribosome small subunit (state g) . SNAP output
|
|
9hny
|
ribosome |
cryo-EM (3.3 Å) |
Zgadzay Y, Mirabello C, Wanes G, Panek T, Chauhan P,
Nystedt B, Zikova A, Whitford PC, Gahura O, Amunts A |
(2025) "Mettl15-Mettl17
modulates the transition from early to late
pre-mitoribosome." Biorxiv. doi: 10.1101/2024.12.18.629302.
|
Mitoribosomal small subunit in complex with mettl15 and
mettl17 . SNAP
output
|
|
9hqv
|
ribosome |
cryo-EM (2.52 Å) |
Shikha S, Tobiasson V, Ferreira Silva M, Ovciarikova
J, Beraldi D, Muhleip A, Sheiner L |
(2025) "Numerous
rRNA molecules form the apicomplexan mitoribosome via
repurposed protein and RNA elements." Nat
Commun, 16, 817. doi: 10.1038/s41467-025-56057-9.
|
cryo-EM structure of the small subunit of the
mitochondrial ribosome from toxoplasma gondii .
SNAP output
|
|
9i05
|
ribosome |
cryo-EM (2.2 Å) |
Shikha S, Tobiasson V, Ferreira Silva M, Ovciarikova
J, Beraldi D, Muhleip A, Sheiner L |
(2025) "Numerous
rRNA molecules form the apicomplexan mitoribosome via
repurposed protein and RNA elements." Nat
Commun, 16, 817. doi: 10.1038/s41467-025-56057-9.
|
cryo-EM structure of the large subunit of the
mitochondrial ribosome from toxoplasma gondii .
SNAP output
|
|
9iiy
|
RNA binding protein-RNA |
cryo-EM (3.0 Å) |
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X,
Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen
EZ |
(2025) "Structural
insights into RNA cleavage by PIWI Argonaute."
Nature, 639, 250-259. doi:
10.1038/s41586-024-08438-1.
|
cryo-EM structure of efpiwi-pirna-target (25-nt,
bilobed) . SNAP
output
|
|
9iiz
|
RNA binding protein-RNA |
cryo-EM (3.8 Å) |
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X,
Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen
EZ |
(2025) "Structural
insights into RNA cleavage by PIWI Argonaute."
Nature, 639, 250-259. doi:
10.1038/s41586-024-08438-1.
|
cryo-EM structure of efpiwi-pirna-target (25-nt, comma)
. SNAP output
|
|
9ij0
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X,
Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen
EZ |
(2025) "Structural
insights into RNA cleavage by PIWI Argonaute."
Nature, 639, 250-259. doi:
10.1038/s41586-024-08438-1.
|
cryo-EM structure of mili-pirna-target (8-nt) .
SNAP output
|
|
9ij1
|
RNA binding protein-RNA |
cryo-EM (3.2 Å) |
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X,
Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen
EZ |
(2025) "Structural
insights into RNA cleavage by PIWI Argonaute."
Nature, 639, 250-259. doi:
10.1038/s41586-024-08438-1.
|
cryo-EM structure of mili-pirna-target (22-nt, bilobed)
. SNAP output
|
|
9ij2
|
RNA binding protein-RNA |
cryo-EM (3.9 Å) |
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X,
Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen
EZ |
(2025) "Structural
insights into RNA cleavage by PIWI Argonaute."
Nature, 639, 250-259. doi:
10.1038/s41586-024-08438-1.
|
cryo-EM structure of mili-pirna-target (22-nt, comma) .
SNAP output
|
|
9ij3
|
RNA binding protein-RNA |
cryo-EM (2.6 Å) |
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X,
Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen
EZ |
(2025) "Structural
insights into RNA cleavage by PIWI Argonaute."
Nature, 639, 250-259. doi:
10.1038/s41586-024-08438-1.
|
cryo-EM structure of mili-pirna-target (26-nt) .
SNAP output
|
|
9ij4
|
RNA binding protein-RNA |
cryo-EM (2.7 Å) |
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X,
Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen
EZ |
(2025) "Structural
insights into RNA cleavage by PIWI Argonaute."
Nature, 639, 250-259. doi:
10.1038/s41586-024-08438-1.
|
cryo-EM structure of mili(k852a)-pirna-target (26-nt) .
SNAP output
|
|
9ij5
|
RNA binding protein-RNA |
cryo-EM (2.8 Å) |
Li Z, Xu Q, Zhong J, Zhang Y, Zhang T, Ying X, Lu X,
Li X, Wan L, Xue J, Huang J, Zhen Y, Zhang Z, Wu J, Shen
EZ |
(2025) "Structural
insights into RNA cleavage by PIWI Argonaute."
Nature, 639, 250-259. doi:
10.1038/s41586-024-08438-1.
|
cryo-EM structure of mili(k853a)-pirna-target .
SNAP output
|
|
9ikz
|
viral protein-RNA |
cryo-EM (3.14 Å) |
Huang YC, Tan LP, Zhao HS, Liu YX, Wang JB, Ge J, Ye
SH, Liu ZY, Lan WQ, Huang B, Zhang HB, Gao Y, Rao ZH, Yan
LM, Lou ZY |
"Substrate selection and transition reveal the
mechanism for RNA capping catalyzed by SARS-CoV-2
NiRAN." |
Sars-cov-2 e-rtc bound to prna-nsp9 and gdp-bef3- .
SNAP output
|
|
9imb
|
RNA binding protein-RNA |
X-ray (2.9 Å) |
Zhong F, Pu T, Hu Q, Li M, Wang L, Wang S, Ruan K,
Shi Y, Sun B, Jiang Y, Lv M |
(2025) "NSUN6
inhibitor discovery guided by its mRNA substrate bound
crystal structure." Structure,
33, 443-450.e4. doi: 10.1016/j.str.2024.12.021.
|
The crystal structure of human m5c methyltransferase
nsun6 bound to its s-adenosyl-l-methionine analog and a
nectin-2 3'-utr RNA substrate . SNAP output
|
|
9ioa
|
antiviral protein-RNA |
cryo-EM (2.59 Å) |
Song XY, Xia Y, Zhang JT, Liu YJ, Qi H, Wei XY, Hu H,
Xia Y, Liu X, Ma YF, Jia N |
(2025) "Bacterial
reverse transcriptase synthesizes long poly-A-rich cDNA
for antiphage defense." Science, eads4639.
doi: 10.1126/science.ads4639.
|
cryo-EM structure of the tetrameric drt9-ncrna complex
. SNAP output
|
|
9iob
|
antiviral protein-RNA |
cryo-EM (2.62 Å) |
Song XY, Xia Y, Zhang JT, Liu YJ, Qi H, Wei XY, Hu H,
Xia Y, Liu X, Ma YF, Jia N |
(2025) "Bacterial
reverse transcriptase synthesizes long poly-A-rich cDNA
for antiphage defense." Science, eads4639.
doi: 10.1126/science.ads4639.
|
cryo-EM structure of the hexameric drt9-ncrna complex .
SNAP output
|
|
9izm
|
DNA binding protein |
cryo-EM (3.02 Å) |
Omura SN, Alfonse LE, Ornstein A, Morinaga H, Hirano
H, Itoh Y, Munoz G, Garrity AJ, Hoffman GR, DiTommaso T,
Yan WX, Cheng DR, Scott DA, Maben Z, Nureki O |
(2025) "Structural
basis for target DNA cleavage and guide RNA processing
by CRISPR-Cas lambda 2." Commun Biol,
8, 876. doi: 10.1038/s42003-025-08300-8.
|
cryo-EM structure of caslambda2-crrna binary complex .
SNAP output
|
|
9j1m
|
ribosome-antibiotic |
cryo-EM (2.33 Å) |
Isozaki Y, Makikawa T, Kimura K, Nishihara D, Fujino
M, Tanaka Y, Hayashi C, Ishizaki Y, Igarashi M, Yokoyama
T, Toshima K, Takahashi D |
(2025) "Creation
of a macrolide antibiotic against non-tuberculous
Mycobacterium using late-stage boron-mediated aglycon
delivery." Sci Adv, 11,
eadt2352. doi: 10.1126/sciadv.adt2352.
|
Ku13-bond mycobacterium tuberculosis 70s ribosome .
SNAP output
|
|
9j8p
|
transferase |
cryo-EM (3.21 Å) |
Yamashita S, Tomita K |
(2025) "Cryo-EM
structure of human TUT1:U6 snRNA complex."
Nucleic Acids Res., 53. doi:
10.1093/nar/gkae1314.
|
cryo-EM structure of human tut1 complexed with u6 snrna
. SNAP output
|
|
9j9h
|
ribosome |
cryo-EM (2.45 Å) |
Go KD, Yan XF, Wirjanata G, Ero R, Pazicky S, Dziekan
J, Tjia S, Lescar J, Bozdech Z, Gao YG |
(2025) "Antimalarial
drug artemisinin stabilizes PfRACK1 binding to the
ribosome." Structure. doi: 10.1016/j.str.2025.05.008.
|
High-resolution cryo-EM structure of the plasmodium
falciparum 80s ribosome bound to rack1 and e-trna .
SNAP output
|
|
9j9i
|
ribosome |
cryo-EM (2.46 Å) |
Go KD, Yan XF, Wirjanata G, Ero R, Pazicky S, Dziekan
J, Tjia S, Lescar J, Bozdech Z, Gao YG |
(2025) "Antimalarial
drug artemisinin stabilizes PfRACK1 binding to the
ribosome." Structure. doi: 10.1016/j.str.2025.05.008.
|
High-resolution cryo-EM structure of the plasmodium
falciparum 80s ribosome bound to e-trna . SNAP output
|
|
9jkd
|
viral protein-RNA |
X-ray (2.34 Å) |
Jia H, Liu S, Rao G, Liu Q, Wu J, Cao S, Gong P |
(2025) "An
evolutionarily unique viral RdRP suggests a common
dual-function feature of the priming element."
Sci Adv, 11, eadv9640. doi:
10.1126/sciadv.adv9640.
|
Crystal structure of aspergillus fumigatus
polymycovirus 1 ploymerase elongation complex .
SNAP output
|
|
9jsb
|
RNA binding protein-RNA |
cryo-EM (2.93 Å) |
Wang F, Xu H, Zhang C, Xue J, Li Z |
(2025) "Target
DNA-induced filament formation and nuclease activation
of SPARDA complex." Cell Res. doi:
10.1038/s41422-025-01100-z.
|
Guide-bound nbasparda complexes . SNAP output
|
|
9k0z
|
ribosome |
cryo-EM (4.7 Å) |
Baid P, Sengupta J |
(2025) "Cryo-EM
structural analyses reveal a unique role for elongation
factor G2 (EF-G2) in Mycobacteria." Febs
J. doi: 10.1111/febs.70161.
|
Ef-g2 bound 70s ribosome complex of m. smegmatis .
SNAP output
|
|
9k10
|
ribosome |
cryo-EM (3.6 Å) |
Baid P, Sengupta J |
(2025) "Cryo-EM
structural analyses reveal a unique role for elongation
factor G2 (EF-G2) in Mycobacteria." Febs
J. doi: 10.1111/febs.70161.
|
Ef-g2 bound 50s ribosome subunit complex of m.
smegmatis . SNAP
output
|
|
9k6p
|
RNA binding protein |
cryo-EM (3.2 Å) |
Li Z, Xu Q, Zhang Y, Zhong J, Zhang T, Xue J, Liu S,
Gao H, Zhang ZZZ, Wu J, Shen EZ |
(2025) "Mechanistic
insights into RNA cleavage by human Argonaute2-siRNA
complex." Cell Res., 35,
453-464. doi: 10.1038/s41422-025-01114-7.
|
cryo-EM structure of hago2d669a-sirna-target (12-nt) .
SNAP output
|
|
9k6q
|
RNA binding protein |
cryo-EM (2.7 Å) |
Li Z, Xu Q, Zhang Y, Zhong J, Zhang T, Xue J, Liu S,
Gao H, Zhang ZZZ, Wu J, Shen EZ |
(2025) "Mechanistic
insights into RNA cleavage by human Argonaute2-siRNA
complex." Cell Res., 35,
453-464. doi: 10.1038/s41422-025-01114-7.
|
"cryo-EM structure of hago2d669a-sirna-target (14-nt,
sesqui-lobed) . SNAP
output
|
|
9k6r
|
RNA binding protein |
cryo-EM (2.7 Å) |
Li Z, Xu Q, Zhang Y, Zhong J, Zhang T, Xue J, Liu S,
Gao H, Zhang ZZZ, Wu J, Shen EZ |
(2025) "Mechanistic
insights into RNA cleavage by human Argonaute2-siRNA
complex." Cell Res., 35,
453-464. doi: 10.1038/s41422-025-01114-7.
|
cryo-EM structure of hago2d669a-sirna-target (14-nt,
uni-lobed) . SNAP
output
|
|
9k6s
|
RNA binding protein |
cryo-EM (2.8 Å) |
Li Z, Xu Q, Zhang Y, Zhong J, Zhang T, Xue J, Liu S,
Gao H, Zhang ZZZ, Wu J, Shen EZ |
(2025) "Mechanistic
insights into RNA cleavage by human Argonaute2-siRNA
complex." Cell Res., 35,
453-464. doi: 10.1038/s41422-025-01114-7.
|
cryo-EM structure of hago2d669a-sirna-target (19-nt) .
SNAP output
|
|
9k6t
|
RNA binding protein |
cryo-EM (2.8 Å) |
Li Z, Xu Q, Zhang Y, Zhong J, Zhang T, Xue J, Liu S,
Gao H, Zhang ZZZ, Wu J, Shen EZ |
(2025) "Mechanistic
insights into RNA cleavage by human Argonaute2-siRNA
complex." Cell Res., 35,
453-464. doi: 10.1038/s41422-025-01114-7.
|
cryo-EM structure of hago2d669a-sirna-target (21-nt) .
SNAP output
|
|
9l09
|
viral protein-RNA |
cryo-EM (2.9 Å) |
Liang L, Meng Y, Chang X, Li E, Huang Y, Yan L, Lou
Z, Peng Y, Zhu B, Yu W, Chang J |
(2025) "Discovery
of a 2'-a-Fluoro-2'-b-C-(fluoromethyl) Purine
Nucleotide Prodrug as a Potential Oral Anti-SARS-CoV-2
Agent." J Med Chem, 68,
1994-2007. doi: 10.1021/acs.jmedchem.4c02769.
|
Sars-cov-2 c-rtc with 13-tp . SNAP output
|
|
9l5r
|
splicing-RNA |
cryo-EM (2.8 Å) |
Li Y, Fischer P, Wang M, Zhou Q, Song A, Yuan R, Meng
W, Chen FX, Luhrmann R, Lau B, Hurt E, Cheng J |
(2025) "Structural
insights into spliceosome fidelity: DHX35-GPATCH1-
mediated rejection of aberrant splicing
substrates." Cell Res.,
35, 296-308. doi: 10.1038/s41422-025-01084-w.
|
cryo-EM structure of the thermophile spliceosome (state
ils) . SNAP output
|
|
9l5s
|
splicing-RNA |
cryo-EM (2.9 Å) |
Li Y, Fischer P, Wang M, Zhou Q, Song A, Yuan R, Meng
W, Chen FX, Luhrmann R, Lau B, Hurt E, Cheng J |
(2025) "Structural
insights into spliceosome fidelity: DHX35-GPATCH1-
mediated rejection of aberrant splicing
substrates." Cell Res.,
35, 296-308. doi: 10.1038/s41422-025-01084-w.
|
cryo-EM structure of the thermophile spliceosome (state
b*q1) . SNAP output
|
|
9l5t
|
splicing-RNA |
cryo-EM (3.5 Å) |
Li Y, Fischer P, Wang M, Zhou Q, Song A, Yuan R, Meng
W, Chen FX, Luhrmann R, Lau B, Hurt E, Cheng J |
(2025) "Structural
insights into spliceosome fidelity: DHX35-GPATCH1-
mediated rejection of aberrant splicing
substrates." Cell Res.,
35, 296-308. doi: 10.1038/s41422-025-01084-w.
|
cryo-EM structure of the thermophile spliceosome (state
b*q2) . SNAP output
|
|
9l6x
|
RNA binding protein |
X-ray (1.89 Å) |
Fukunaga K, Teramoto T, Nakashima M, Ohtani T,
Katsuki R, Matsuura T, Yokobayashi Y, Kakuta Y |
(2025) "Structural
insights into lab-coevolved RNA-RBP pairs and
applications of synthetic riboswitches in cell-free
system." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf212.
|
Crystal structure of the l7ae derivative protein ls4 in
complex with its co-evolved target cs1 RNA . SNAP output
|
|
9l6y
|
RNA binding protein |
X-ray (3.12 Å) |
Fukunaga K, Teramoto T, Nakashima M, Ohtani T,
Katsuki R, Matsuura T, Yokobayashi Y, Kakuta Y |
(2025) "Structural
insights into lab-coevolved RNA-RBP pairs and
applications of synthetic riboswitches in cell-free
system." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf212.
|
Crystal structure of the l7ae derivative protein ls12
in complex with its co-evolved target cs2 RNA .
SNAP output
|
|
9lpc
|
ligase-RNA |
X-ray (2.82 Å) |
Peng X, Xia K, Huang Q, Xiang M, Han L, Qiu H, Gu Q,
Chen B, Zhou H |
"The lineage-specific tRNA recognition mechanism of
bacterial trptophanyl-tRNA synthetase and its
implications for inhibitor discover." |
Crystal structure of escherichia coli trptophanyl-trna
synthetase in complex with trna(trp) . SNAP output
|
|
9mor
|
ribosome |
cryo-EM (2.65 Å) |
Tian Y, Li Q, Fatma S, Jiang J, Jin H, Zeng F, Huang
RH |
(2025) "Molecular
and structural basis of a subfamily of PrfH rescuing
both the damaged and intact ribosomes stalled in
translation." Biorxiv. doi: 10.1101/2025.01.09.632186.
|
Damaged 70s ribosome with prfh bound . SNAP output
|
|
9mq4
|
ribosome |
cryo-EM (2.78 Å) |
Tian Y, Li Q, Fatma S, Jiang J, Jin H, Zeng F, Huang
RH |
(2025) "Molecular
and structural basis of a subfamily of PrfH rescuing
both the damaged and intact ribosomes stalled in
translation." Biorxiv. doi: 10.1101/2025.01.09.632186.
|
Damaged 70s ribosome with prfh bound . SNAP output
|
|
9mtp
|
ribosome |
X-ray (2.4 Å) |
Aleksandrova EV, Syroegin EA, Basu RS, Vassilevski
AA, Gagnon MG, Polikanov YS |
(2025) "Mechanism
of release factor-mediated peptidyl-tRNA hydrolysis on
the ribosome." Science,
388, eads9030. doi: 10.1126/science.ads9030.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with mrna, a-site
q230-n5-methylated release factor 1, and p-site
fmeaaakc-peptidyl-trnacys at 2.40a resolution .
SNAP output
|
|
9mtq
|
ribosome |
X-ray (2.55 Å) |
Aleksandrova EV, Syroegin EA, Basu RS, Vassilevski
AA, Gagnon MG, Polikanov YS |
(2025) "Mechanism
of release factor-mediated peptidyl-tRNA hydrolysis on
the ribosome." Science,
388, eads9030. doi: 10.1126/science.ads9030.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with mrna, a-site ggd-mutant
release factor 1, and p-site fmeaaakc-peptidyl-trnacys
at 2.55a resolution . SNAP output
|
|
9mtr
|
ribosome |
X-ray (2.8 Å) |
Aleksandrova EV, Syroegin EA, Basu RS, Vassilevski
AA, Gagnon MG, Polikanov YS |
(2025) "Mechanism
of release factor-mediated peptidyl-tRNA hydrolysis on
the ribosome." Science,
388, eads9030. doi: 10.1126/science.ads9030.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with mrna, a-site ggs-mutant
release factor 1, and p-site fmeaaakc-peptidyl-trnacys
at 2.80a resolution . SNAP output
|
|
9mts
|
ribosome |
X-ray (2.7 Å) |
Aleksandrova EV, Syroegin EA, Basu RS, Vassilevski
AA, Gagnon MG, Polikanov YS |
(2025) "Mechanism
of release factor-mediated peptidyl-tRNA hydrolysis on
the ribosome." Science,
388, eads9030. doi: 10.1126/science.ads9030.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with mrna, a-site
q230-unmodified release factor 1, and p-site
fmeaaakc-peptidyl-trnacys at 2.70a resolution .
SNAP output
|
|
9mtt
|
ribosome |
X-ray (2.6 Å) |
Aleksandrova EV, Syroegin EA, Basu RS, Vassilevski
AA, Gagnon MG, Polikanov YS |
(2025) "Mechanism
of release factor-mediated peptidyl-tRNA hydrolysis on
the ribosome." Science,
388, eads9030. doi: 10.1126/science.ads9030.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with mrna, a-site
q230-n5-methylated release factor 1, and p-site
deacylated-trnacys at 2.60a resolution . SNAP output
|
|
9mud
|
antiviral protein |
cryo-EM (3.4 Å) |
Baca CF, Majumder P, Hickling JH, Patel DJ,
Marraffini LA |
(2025) "Cat1
forms filament networks to degrade NAD + during the
type III CRISPR-Cas antiviral response."
Science, eadv9045. doi: 10.1126/science.adv9045.
|
cryo-EM structure of crispr-associated ca4 bound cat1
pentagonal filament assembly . SNAP output
|
|
9mue
|
antiviral protein |
cryo-EM (4.0 Å) |
Baca CF, Majumder P, Hickling JH, Patel DJ,
Marraffini LA |
(2025) "Cat1
forms filament networks to degrade NAD + during the
type III CRISPR-Cas antiviral response."
Science, eadv9045. doi: 10.1126/science.adv9045.
|
cryo-EM structure of crispr-associated ca4 bound cat1
pentagonal filament assembly in the presence of nad
(adpr modelled) . SNAP
output
|
|
9muj
|
transferase-RNA |
X-ray (2.006 Å) |
Tanouti Y, Roovers M, Wolff P, Lechner A, Van Elder
D, Feller A, Soin R, Gueydan C, Kruys V, Droogmans L,
Labar G |
(2025) "Structural
insight into the novel Thermus thermophilus SPOUT
methyltransferase RlmR catalysing Um2552 formation in
the 23S rRNA A-loop: a case of convergent
evolution." Nucleic Acids Res.,
53. doi: 10.1093/nar/gkaf432.
|
Rlmr 23s rrna methyltransferase from thermus
thermophilus in complex with methylated rrna (um2552)
and s-adenosyl-l-homocysteine (sah) . SNAP output
|
|
9muo
|
antiviral protein |
cryo-EM (3.3 Å) |
Baca CF, Majumder P, Hickling JH, Patel DJ,
Marraffini LA |
(2025) "Cat1
forms filament networks to degrade NAD + during the
type III CRISPR-Cas antiviral response."
Science, eadv9045. doi: 10.1126/science.adv9045.
|
cryo-EM structure of crispr-associated ca4 bound cat1
pentagonal filament assembly in the presence of nad
analog bad . SNAP
output
|
|
9mw6
|
antiviral protein-RNA |
cryo-EM (3.4 Å) |
Aderounmu AM, Maus-Conn J, Consalvo CD, Shen PS, Bass
BL |
(2025) "Biochemical
and structural basis of Dicer helicase function
unveiled by resurrecting ancient proteins."
Proc.Natl.Acad.Sci.USA, 122,
e2500825122. doi: 10.1073/pnas.2500825122.
|
cryo-EM structure of ancestral dicer helicase bound to
27-bp dsrna . SNAP
output
|
|
9mw7
|
antiviral protein-RNA |
cryo-EM (3.4 Å) |
Aderounmu AM, Maus-Conn J, Consalvo CD, Shen PS, Bass
BL |
(2025) "Biochemical
and structural basis of Dicer helicase function
unveiled by resurrecting ancient proteins."
Proc.Natl.Acad.Sci.USA, 122,
e2500825122. doi: 10.1073/pnas.2500825122.
|
cryo-EM structure of ancestral dicer helicase bound to
27-bp dsrna in end-bound transition state . SNAP output
|
|
9mw8
|
antiviral protein-RNA |
cryo-EM (3.3 Å) |
Aderounmu AM, Maus-Conn J, Consalvo CD, Shen PS, Bass
BL |
(2025) "Biochemical
and structural basis of Dicer helicase function
unveiled by resurrecting ancient proteins."
Proc.Natl.Acad.Sci.USA, 122,
e2500825122. doi: 10.1073/pnas.2500825122.
|
cryo-EM structure of ancestral dicer helicase bound to
27-bp dsrna in post-hydrolysis closed state . SNAP output
|
|
9mw9
|
antiviral protein |
cryo-EM (3.0 Å) |
Baca CF, Majumder P, Hickling JH, Patel DJ,
Marraffini LA |
(2025) "Cat1
forms filament networks to degrade NAD + during the
type III CRISPR-Cas antiviral response."
Science, eadv9045. doi: 10.1126/science.adv9045.
|
cryo-EM structure of crispr-associated ca4 bound cat1
trigonal filament assembly . SNAP output
|
|
9mx3
|
antiviral protein-RNA |
cryo-EM (3.0 Å) |
Aderounmu AM, Maus-Conn J, Consalvo CD, Shen PS, Bass
BL |
(2025) "Biochemical
and structural basis of Dicer helicase function
unveiled by resurrecting ancient proteins."
Proc.Natl.Acad.Sci.USA, 122,
e2500825122. doi: 10.1073/pnas.2500825122.
|
cryo-EM structure of ancestral dicer helicase bound to
27-bp dsrna in post-hydrolysis semi-closed state .
SNAP output
|
|
9mx5
|
antiviral protein-RNA |
cryo-EM (3.1 Å) |
Aderounmu AM, Maus-Conn J, Consalvo CD, Shen PS, Bass
BL |
(2025) "Biochemical
and structural basis of Dicer helicase function
unveiled by resurrecting ancient proteins."
Proc.Natl.Acad.Sci.USA, 122,
e2500825122. doi: 10.1073/pnas.2500825122.
|
cryo-EM structure of ancestral dicer helicase bound to
27-bp dsrna in internally-bound transition state .
SNAP output
|
|
9n2b
|
ribosome |
cryo-EM (2.2 Å) |
Welfer GA, Brady RA, Natchiar SK, Watson ZL, Rundlet
EJ, Alejo JL, Singh AP, Mishra NK, Altman RB, Blanchard
SC |
(2025) "Impacts
of ribosomal RNA sequence variation on gene expression
and phenotype." Philos.Trans.R.Soc.Lond.B
Biol.Sci., 380, 20230379. doi:
10.1098/rstb.2023.0379.
|
Impacts of ribosomal RNA sequence variation on gene
expression and phenotype: cryo-EM structure of the rrsb
ribosome (bbb-70s) . SNAP output
|
|
9n2c
|
ribosome |
cryo-EM (2.4 Å) |
Welfer GA, Brady RA, Natchiar SK, Watson ZL, Rundlet
EJ, Alejo JL, Singh AP, Mishra NK, Altman RB, Blanchard
SC |
(2025) "Impacts
of ribosomal RNA sequence variation on gene expression
and phenotype." Philos.Trans.R.Soc.Lond.B
Biol.Sci., 380, 20230379. doi:
10.1098/rstb.2023.0379.
|
Impacts of ribosomal RNA sequence variation on gene
expression and phenotype: cryo-EM structure of the rrsh
ribosome (hbb-70s) . SNAP output
|
|
9njf
|
ribosome |
cryo-EM (3.4 Å) |
Singh S, Hunt JF |
"E. coli pre-elongation complex without an A-site
tRNA with EQ2-YbiT in Non-hydrolytic 1/PtIM(a)
conformation." |
E. coli pre-elongation complex without an a-site trna
with eq2-ybit in non-hydrolytic 1-ptim(a) conformation
. SNAP output
|
|
9njv
|
ribosome |
cryo-EM (3.1 Å) |
Hunt JF, Singh S |
"E. coli 70S initiation complex (bL33 absent)." |
E. coli 70s initiation complex (bl33 absent) . SNAP output
|
|
9nkl
|
ribosome |
cryo-EM (3.3 Å) |
Hunt JF, Singh S |
"E. coli 70S initiation complex." |
E. coli 70s initiation complex . SNAP output
|
|
9nl5
|
ribosome |
cryo-EM (3.0 Å) |
Singh S, Hunt JF |
"E. coli pre-elongation complex without an A-site
tRNA with EttA-EQ2." |
E. coli pre-elongation complex without an a-site trna
with eq2-etta in hydrolytic 1 conformation . SNAP output
|
|
9nl6
|
ribosome |
cryo-EM (3.2 Å) |
Singh S, Hunt JF |
"E. coli initiation complex with EQ2-YbiT in
Non-hydrolytic 1/PtIM(a) conformation." |
E. coli initiation complex with eq2-ybit in
non-hydrolytic 1-ptim(a) conformation . SNAP output
|
|
9nl7
|
ribosome |
cryo-EM (3.3 Å) |
Hunt JF, Singh S |
"E. coli initiation complex with EQ2-YbiT in
Non-hydrolytic 2/PtIM(b) conformation." |
E. coli initiation complex with eq2-ybit in
non-hydrolytic 2-ptim(b) conformation . SNAP output
|
|
9nlb
|
ribosome |
cryo-EM (3.2 Å) |
Hunt JF, Singh S |
"E. coli initiation complex with EQ2-EttA in
Hydrolytic 2 conformation." |
E. coli initiation complex with eq2-etta in hydrolytic
2 conformation . SNAP
output
|
|
9nle
|
ribosome |
cryo-EM (3.2 Å) |
Hunt JF, Singh S |
"ABCF PtIM positioning affects tRNA dynamics." |
E. coli initiation complex with eq2-etta in hydrolytic
1 conformation . SNAP
output
|
|
9nlf
|
ribosome |
cryo-EM (3.2 Å) |
Hunt JF, Singh S |
"E. coli initiation complex with EQ2-YbiT in
Hydrolytic 2/PtIM(a) conformation." |
E. coli initiation complex with eq2-ybit in hydrolytic
2-ptim(a) conformation . SNAP output
|
|
9nlh
|
ribosome |
cryo-EM (3.1 Å) |
Hunt JF, Singh S |
"E.coli Initiation complex with YheS-EQ2." |
E.coli initiation complex with yhes-eq2 . SNAP output
|
|
9nlj
|
ribosome |
cryo-EM (3.1 Å) |
Hunt JF, Singh S |
"E.coli Initiation complex with Uup-EQ2." |
E.coli initiation complex with uup-eq2 . SNAP output
|
|
9nlq
|
ribosome |
cryo-EM (3.3 Å) |
Hunt JF, Singh S |
"E.coli Initiation complex with YbiT-EQ2
(Hydrolytic-II)." |
E. coli initiation complex with eq2-ybit in hydrolytic
1-ptim(a) conformation . SNAP output
|
|
9nls
|
ribosome |
cryo-EM (3.3 Å) |
Singh S, Hunt JF |
"E. coli initiation complex with EQ2-YbiT in
Intermediate/PtIM(b) conformation." |
E. coli initiation complex with eq2-ybit in
intermediate-ptim(b) conformation . SNAP output
|
|
9nlv
|
immune system |
cryo-EM (2.6 Å) |
Tang S, Zedaveinyte R, Burman N, Pandey S, Ramirez
JL, Kulber LM, Wiegand T, Wilkinson RA, Ma Y, Zhang DJ,
Lampe GD, Berisa M, Jovanovic M, Wiedenheft B, Sternberg
SH |
(2025) "Protein-primed
homopolymer synthesis by an antiviral reverse
transcriptase." Nature. doi: 10.1038/s41586-025-09179-5.
|
cryo-EM structure of hexameric sendrt9 rt-ncrna complex
. SNAP output
|
|
9nlx
|
immune system |
cryo-EM (3.2 Å) |
Tang S, Zedaveinyte R, Burman N, Pandey S, Ramirez
JL, Kulber LM, Wiegand T, Wilkinson RA, Ma Y, Zhang DJ,
Lampe GD, Berisa M, Jovanovic M, Wiedenheft B, Sternberg
SH |
(2025) "Protein-primed
homopolymer synthesis by an antiviral reverse
transcriptase." Nature. doi: 10.1038/s41586-025-09179-5.
|
cryo-EM structure of the trimeric sendrt9 rt-ncrna
complex (gst fusion) . SNAP output
|
|
9no7
|
ribosome |
cryo-EM (2.13 Å) |
Aleksandrova EV, Syroegin EA, Basu RS, Vassilevski
AA, Gagnon MG, Polikanov YS |
(2025) "Mechanism
of release factor-mediated peptidyl-tRNA hydrolysis on
the ribosome." Science,
388, eads9030. doi: 10.1126/science.ads9030.
|
cryo-EM structure of the wild-type thermus thermophilus
70s ribosome in complex with mrna, a-site
q230-n5-methylated release factor 1, and p-site
2'-deoxy-a76-fmeaaakc-peptidyl-trnacys at 2.13a
resolution . SNAP
output
|
|
9npx
|
ribosome |
cryo-EM (2.1 Å) |
Gen R, Addetia A, Asarnow D, Park YJ, Quispe J, Chan
MC, Brown JT, Lee J, Campbell MG, Lapointe CP, Veesler
D |
(2025) "SARS-CoV-2
nsp1 mediates broad inhibition of translation in
mammals." Cell Rep, 44,
115696. doi: 10.1016/j.celrep.2025.115696.
|
Sars-cov-2 nsp1 bound to the rhinolophus lepidus 40s
ribosomal subunit (local refinement of the 40s body) .
SNAP output
|
|
9npy
|
ribosome |
cryo-EM (2.1 Å) |
Gen R, Addetia A, Asarnow D, Park YJ, Quispe J, Chan
MC, Brown JT, Lee J, Campbell MG, Lapointe CP, Veesler
D |
(2025) "SARS-CoV-2
nsp1 mediates broad inhibition of translation in
mammals." Cell Rep, 44,
115696. doi: 10.1016/j.celrep.2025.115696.
|
Sars-cov-2 nsp1 bound to the rhinolophus lepidus 40s
ribosome (local refinement of the 40s head) . SNAP output
|
|
9nyy
|
RNA binding protein |
cryo-EM (2.73 Å) |
Van Riper J, Martinez-Claros AO, Wang L, Schneiderman
HE, Maheshwari S, Pillon MC |
(2025) "CryoEM structure of the SLFN14 endoribonuclease
reveals insight into RNA binding and cleavage." Nat
Commun, 16, 5848. doi: 10.1038/s41467-025-61091-8.
|
Nucleic acid bound human slfn14, state 1 . SNAP output
|
|
9o3h
|
ribosome |
X-ray (2.65 Å) |
Syroegin EA, Aleksandrova EV, Kruglov AA, Paranjpe
MN, Svetlov MS, Polikanov YS |
(2025) "Structural
insights into context-specific inhibition of bacterial
translation by macrolides." Biorxiv. doi:
10.1101/2025.06.03.657637.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with macrolide erythromycin,
mrna, aminoacylated a-site lys-trnalys, p-site
fmrc-peptidyl-trnamet, and deacylated e-site trnalys at
2.65a resolution . SNAP
output
|
|
9o3i
|
ribosome |
X-ray (2.8 Å) |
Syroegin EA, Aleksandrova EV, Kruglov AA, Paranjpe
MN, Svetlov MS, Polikanov YS |
(2025) "Structural
insights into context-specific inhibition of bacterial
translation by macrolides." Biorxiv. doi:
10.1101/2025.06.03.657637.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with ketolide telithromycin,
mrna, aminoacylated a-site lys-trnalys, p-site
fmrc-peptidyl-trnamet, and deacylated e-site trnalys at
2.80a resolution . SNAP
output
|
|
9o3j
|
ribosome |
X-ray (2.6 Å) |
Syroegin EA, Aleksandrova EV, Kruglov AA, Paranjpe
MN, Svetlov MS, Polikanov YS |
(2025) "Structural
insights into context-specific inhibition of bacterial
translation by macrolides." Biorxiv. doi:
10.1101/2025.06.03.657637.
|
Crystal structure of the wild-type drug-free thermus
thermophilus 70s ribosome in complex with mrna,
aminoacylated a-site lys-trnalys, p-site
fmrc-peptidyl-trnamet, and deacylated e-site trnalys at
2.60a resolution . SNAP
output
|
|
9o3k
|
ribosome |
X-ray (2.7 Å) |
Syroegin EA, Aleksandrova EV, Kruglov AA, Paranjpe
MN, Svetlov MS, Polikanov YS |
(2025) "Structural
insights into context-specific inhibition of bacterial
translation by macrolides." Biorxiv. doi:
10.1101/2025.06.03.657637.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with macrolide erythromycin,
mrna, aminoacylated a-site lys-trnalys, p-site
fmac-peptidyl-trnamet, and deacylated e-site trnalys at
2.70a resolution . SNAP
output
|
|
9o3l
|
ribosome |
X-ray (2.75 Å) |
Syroegin EA, Aleksandrova EV, Kruglov AA, Paranjpe
MN, Svetlov MS, Polikanov YS |
(2025) "Structural
insights into context-specific inhibition of bacterial
translation by macrolides." Biorxiv. doi:
10.1101/2025.06.03.657637.
|
Crystal structure of the wild-type thermus thermophilus
70s ribosome in complex with macrolide erythromycin,
mrna, deacylated a-site trnaphe, p-site
fmrc-peptidyl-trnamet, and deacylated e-site trnaphe at
2.75a resolution . SNAP
output
|
|
9ofv
|
structural protein |
cryo-EM (3.16 Å) |
Li W, Cahoon T, Shen PS |
"Mechanism of nascent chain removal by the
Ribosome-associated Quality Control complex." |
Consensus reconstruction of the eukaryotic
ribosome-associated quality control complex . SNAP output
|
|
9p6p
|
transferase, viral protein |
X-ray (1.95 Å) |
Minasov G, Shuvalova L, Maltseva N, Kim Y, Kiryukhina
O, Joachimiak A, Satchell KJF, Center for Structural
Biology of Infectious Diseases (CSBID) |
"Crystal Structure of the SARS-CoV-2
2'-O-Methyltransferase with (m7GpppA)pUpU (Cap-0) and
S-Adenosyl-L-homocysteine (SAH)." |
Crystal structure of the sars-cov-2
2'-o-methyltransferase with (m7gpppa)pupu (cap-0) and
s-adenosyl-l-homocysteine (sah). . SNAP output
|
|
9q87
|
ribosome |
cryo-EM (1.55 Å) |
Leonarski F, Henning-Knechtel A, Kirmizialtin S,
Ennifar E, Auffinger P |
(2024) "Principles of ion binding to RNA inferred from
the analysis of a 1.55 Angs. resolution bacterial
ribosome structure - Part I: Mg2+." Nucleic Acids
Res. doi: 10.1093/nar/gkae1235.
|
Principles of ion binding to RNA inferred from the
analysis of a 1.55 angstrom resolution bacterial
ribosome structure - part i: mg2+ . SNAP output
|
|
9qeg
|
ribosome |
cryo-EM (2.21 Å) |
Rivalta A, Fedorenko A, Le Scornet A, Thompson S,
Halfon Y, Breiner Goldstein E, Cavdaroglu S, Melenitzky
T, Hiregange DG, Zimmerman E, Bashan A, Yap MF, Yonath
A |
(2025) "Structural
studies on ribosomes of differentially
macrolide-resistant Staphylococcus aureus strains."
Life Sci Alliance, 8. doi:
10.26508/lsa.202503325.
|
cryo-EM structure of the 70s ribosome of a mlsb
sensitive s. aureus strain "kes34" in complex with
solithromycin . SNAP
output
|
|
9qeh
|
ribosome |
cryo-EM (2.08 Å) |
Rivalta A, Fedorenko A, Le Scornet A, Thompson S,
Halfon Y, Breiner Goldstein E, Cavdaroglu S, Melenitzky
T, Hiregange DG, Zimmerman E, Bashan A, Yap MF, Yonath
A |
(2025) "Structural
studies on ribosomes of differentially
macrolide-resistant Staphylococcus aureus strains."
Life Sci Alliance, 8. doi:
10.26508/lsa.202503325.
|
cryo-EM structure of the a2085-methylated 50s ribosome
of a mlsb resistant s. aureus strain "mny196" in
complex with solithromycin . SNAP output
|
|
9qiw
|
ribosome |
cryo-EM (3.04 Å) |
Fiorentino F, Thoms M, Wild K, Denk T, Cheng J, Zeman
J, Sinning I, Hurt E, Beckmann R |
(2025) "Highly
conserved ribosome biogenesis pathways between human
and yeast revealed by the MDN1-NLE1 interaction and
NLE1 containing pre-60S subunits." Nucleic
Acids Res., 53. doi: 10.1093/nar/gkaf255.
|
Human pre-60s - state 3 . SNAP output
|
|
9qrp
|
RNA binding protein |
X-ray (2.7 Å) |
Cusack S, Yaremchuk A, Tukalo M |
(1996) "The
crystal structure of the ternary complex of
T.thermophilus seryl-tRNA synthetase with tRNA(Ser) and
a seryl-adenylate analogue reveals a conformational
switch in the active site." EMBO J,
15, 2834-2842.
|
Thermus thermophilus seryl-trna synthetase bound to
trna(ser)(gga) and seryl-adenylate analogue. . SNAP output
|
|
9qt5
|
ribosome |
cryo-EM (3.13 Å) |
Ekemezie CL, Chan LI, Brown CR, Helena-Bueno K,
Williams TA, Melnikov SV |
"Evolution of drug-binding sites in bacterial
ribosomes." |
Structure of the 50s ribosomal subunit from the
antibiotic-producing bacterium streptomyces fradiae .
SNAP output
|
|
9uht
|
viral protein-RNA |
cryo-EM (2.89 Å) |
Huang Y, Tan L, Liu Y, Yan L, Rao Z, Lou Z |
"Response to Matter Arising: Substrate selection and
transition state support the mechanism for GTP-mediate
RNA capping catalyzed by SARS-CoV-2 NiRAN." |
Sars-cov-2 e-rtc in complex with RNA-nsp9 and gmppnp .
SNAP output
|