5mC-DNA-protein interactions for PDB entry 4lg7

Summary information and primary citation

PDB-id: 4lg7; SNAP-derived features in text and JSON formats; DNAproDB
Class: hydrolase-DNA
Method: X-ray (2.5 Å)
Summary: Crystal structure mbd4 mbd domain in complex with methylated cpg DNA
Reference: Xu C, Tempel W, Wernimont AK, Bountra C, Arrowsmith CH, Edwards AM, Min J: "Crystal structure MBD4 MBD domain in complex with methylated CpG DNA."
Abstract

The contacts include paired nucleotides (mostly a G in Watson-Crick G-C pairing), and amino-acids within a 4.5-A distance cutoff to base atoms of 5mC.
The structure is oriented in the base reference frame of 5mC, allowing for easy comparison and direct superimposition between entries.
The black sphere (•) denotes the 5-methyl carbon atom in 5mC.

No. 1 B.5CM6: `stacking-with-A.ARG119 is-WC-paired is-in-duplex [+]:AcG/cGT`

No. 2 C.5CM6: `stacking-with-A.ARG97 is-WC-paired is-in-duplex [-]:cGT/AcG`