5mC-DNA-protein interactions for PDB entry 5szx [5mC-protein List · SNAP web server]
Summary information and primary citation
- PDB-id
- 5szx; SNAP-derived features in text and JSON formats; DNAproDB
- Class
- transcription regulator-DNA
- Method
- X-ray (2.251 Å)
- Summary
- Epstein-barr virus zta DNA binding domain homodimer in complex with methylated DNA
- Reference
- Hong S, Wang D, Horton JR, Zhang X, Speck SH, Blumenthal RM, Cheng X (2017): "Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta." Nucleic Acids Res., 45, 2503-2515. doi: 10.1093/nar/gkx057.
- Abstract
Cartoon-block schematics in six views (download the tarball)
List of 2 5mC-amino acid contacts
- The contacts include paired nucleotides (mostly a G in Watson-Crick G-C pairing), and amino-acids within a 4.5-A distance cutoff to base atoms of 5mC.
- The structure is oriented in the base reference frame of 5mC, allowing for easy comparison and direct superimposition between entries.
- The black sphere (•) denotes the 5-methyl carbon atom in 5mC.
