Summary information and primary citation
- PDB-id
- 8c57; SNAP-derived features in text and JSON formats;
DNAproDB
- Class
- transferase
- Method
- X-ray (1.95 Å)
- Summary
- Cpg specific m.mpei methyltransferase crystallized in the presence of 5,6-dihydro-5-azacytosine (converted to 5m-dhac) and 5-methylcytosine containing dsDNA
- Reference
- Wojciechowski M, Czapinska H, Krwawicz J, Rafalski D, Bochtler M: "Cytosine analogues as DNA methyltransferase substrates and inhibitors."
- Abstract
-
- The contacts include paired nucleotides (mostly a G in Watson-Crick G-C pairing), and
amino-acids within a 4.5-A distance cutoff to base atoms of 5mC.
- The structure is oriented in the base reference frame of 5mC, allowing for easy comparison
and direct superimposition between entries.
- The black sphere (•) denotes the 5-methyl carbon atom in 5mC.
No. 1 C.5CM7: stacking-with-A.PHE302 is-WC-paired is-in-duplex [-]:GGC/GcC |
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