Summary information and primary citation

PDB-id
1sfo; SNAP-derived features in text and JSON formats; DNAproDB
Class
transcription-DNA-RNA hybrid
Method
X-ray (3.61 Å)
Summary
RNA polymerase ii strand separated elongation complex
Reference
Westover KD, Bushnell DA, Kornberg RD (2004): "Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II." Science, 303, 1014-1016. doi: 10.1126/science.1090839.
Abstract
The structure of an RNA polymerase II-transcribing complex has been determined in the posttranslocation state, with a vacancy at the growing end of the RNA-DNA hybrid helix. At the opposite end of the hybrid helix, the RNA separates from the template DNA. This separation of nucleic acid strands is brought about by interaction with a set of proteins loops in a strand/loop network. Formation of the network must occur in the transition from abortive initiation to promoter escape.

Cartoon-block schematics in six views (download the tarball)

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