SNAP output for PDB entry 1tf3 [SNAP web server]

PDB-id

1tf3; SNAP-derived features in text and JSON formats; DNAproDB

Class

transcription-DNA

Method

NMR

Summary

Tfiiia finger 1-3 bound to DNA, NMR, 22 structures

Reference

Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE (1997): "Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA." Nat.Struct.Biol., 4, 605-608. doi: 10.1038/nsb0897-605.

Abstract

The three N-terminal zinc fingers of transcription factor IIIA bind in the DNA major groove. Substantial packing interfaces are formed between adjacent fingers, the linkers lose their intrinsic flexibility upon DNA binding, and several lysine side chains implicated in DNA recognition are dynamically disordered.