Summary information and primary citation

PDB-id
1xnq; SNAP-derived features in text and JSON formats; DNAproDB
Class
ribosome
Method
X-ray (3.05 Å)
Summary
Structure of an inosine-adenine wobble base pair complex in the context of the decoding center
Reference
Murphy FV, Ramakrishnan V (2004): "Structure of a purine-purine wobble base pair in the decoding center of the ribosome." Nat.Struct.Mol.Biol., 11, 1251-1252. doi: 10.1038/nsmb866.
Abstract
Here we report the crystal structures of I.C and I.A wobble base pairs in the context of the ribosomal decoding center, clearly showing that the I.A base pair is of an I(anti).A(anti) conformation, as predicted by Crick. Additionally, the structures enable the observation of changes in the anticodon to allow purine-purine base pairing, the 'widest' base pair geometry allowed in the wobble position.

Cartoon-block schematics in six views (download the tarball)

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