Summary information and primary citation
- PDB-id
- 1xnr; SNAP-derived features in text and JSON formats;
DNAproDB
- Class
- ribosome
- Method
- X-ray (3.1 Å)
- Summary
- Crystal structure of an inosine-cytosine wobble base pair in the context of the decoding center
- Reference
- Murphy FV, Ramakrishnan V (2004): "Structure of a purine-purine wobble base pair in the decoding center of the ribosome." Nat.Struct.Mol.Biol., 11, 1251-1252. doi: 10.1038/nsmb866.
- Abstract
- Here we report the crystal structures of I.C and I.A wobble base pairs in the context of the ribosomal decoding center, clearly showing that the I.A base pair is of an I(anti).A(anti) conformation, as predicted by Crick. Additionally, the structures enable the observation of changes in the anticodon to allow purine-purine base pairing, the 'widest' base pair geometry allowed in the wobble position.
