SNAP output for PDB entry 1ytf [SNAP web server]

PDB-id

1ytf; SNAP-derived features in text and JSON formats; DNAproDB

Class

transcription-DNA

Method

X-ray (2.5 Å)

Summary

Yeast tfiia-tbp-DNA complex

Reference

Tan S, Hunziker Y, Sargent DF, Richmond TJ (1996): "Crystal structure of a yeast TFIIA/TBP/DNA complex." Nature, 381, 127-134. doi: 10.1038/381127a0.

Abstract

The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors.