Summary information and primary citation

PDB-id
3ubt; SNAP-derived features in text and JSON formats; DNAproDB
Class
transferase-DNA
Method
X-ray (2.502 Å)
Summary
Crystal structure of c71s mutant of DNA cytosine-5 methyltransferase m.haeiii bound to DNA
Reference
Didovyk A, Verdine GL (2012): "Structural origins of DNA target selection and nucleobase extrusion by a DNA Cytosine methyltransferase." J.Biol.Chem., 287, 40099-40105. doi: 10.1074/jbc.M112.413054.
Abstract
Background: How DNA 5-cytosine methyltransferases (DCMTases) select their substrate nucleobase for extrusion from DNA duplex is poorly understood.
Results: The crystal structure of a pre-extrusion M.HaeIII DCMTase-substrate DNA complex is reported here.

Cartoon-block schematics in six views (download the tarball)

PyMOL session file Download PDB file View in 3Dmol.js