Summary information and primary citation

PDB-id
4k8x; SNAP-derived features in text and JSON formats; DNAproDB
Class
transferase-DNA
Method
X-ray (2.28 Å)
Summary
Binary complex of 9n DNA polymerase in the replicative state
Reference
Bergen K, Betz K, Welte W, Diederichs K, Marx A (2013): "Structures of KOD and 9N DNA Polymerases Complexed with Primer Template Duplex." Chembiochem, 14, 1058-1062. doi: 10.1002/cbic.201300175.
Abstract
Replicate it: Structures of KOD and 9°N DNA polymerases, two enzymes that are widely used to replicate DNA with highly modified nucleotides, were solved at high resolution in complex with primer/template duplex. The data elucidate substrate interaction of the two enzymes and pave the way for further optimisation of the enzymes and substrates.

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