Summary information and primary citation
- PDB-id
- 4k8x; SNAP-derived features in text and JSON formats;
DNAproDB
- Class
- transferase-DNA
- Method
- X-ray (2.28 Å)
- Summary
- Binary complex of 9n DNA polymerase in the replicative state
- Reference
- Bergen K, Betz K, Welte W, Diederichs K, Marx A (2013): "Structures of KOD and 9N DNA Polymerases Complexed with Primer Template Duplex." Chembiochem, 14, 1058-1062. doi: 10.1002/cbic.201300175.
- Abstract
- Replicate it: Structures of KOD and 9°N DNA polymerases, two enzymes that are widely used to replicate DNA with highly modified nucleotides, were solved at high resolution in complex with primer/template duplex. The data elucidate substrate interaction of the two enzymes and pave the way for further optimisation of the enzymes and substrates.