SNAP output for PDB entry 5thg [SNAP web server]

PDB-id

5thg; SNAP-derived features in text and JSON formats; DNAproDB

Class

hydrolase-DNA

Method

X-ray (3.106 Å)

Summary

Engineered variant of i-onui meganuclease targeting the hiv ccr5 gene; harbors 43 point mutations relative to wild-type i-onui

Reference

Werther R, Hallinan JP, Lambert A, Haven K, Jarjor J, Stoddard BL: "The structural basis of altered gene specificity resulting from meganuclease and MegaTAL engineering."

Abstract