SNAP output for PDB entry 6l97 [SNAP web server]

PDB-id

6l97; SNAP-derived features in text and JSON formats; DNAproDB

Class

DNA binding protein-DNA

Method

X-ray (2.362 Å)

Summary

Complex of DNA polymerase iv and l-DNA duplex

Reference

An J, Choi J, Hwang D, Park J, Pemble 4th CW, Duong THM, Kim KR, Ahn H, Chung HS, Ahn DR (2020): "The crystal structure of a natural DNA polymerase complexed with mirror DNA." Chem.Commun.(Camb.), 56, 2186-2189. doi: 10.1039/c9cc09351f.

Abstract

The intrinsic l-DNA binding properties of a natural DNA polymerase was discovered. The binding affinity of Dpo4 polymerase for l-DNA was comparable to that for d-DNA. The crystal structure of Dpo4/l-DNA complex revealed a dimer formed by the little finger domain that provides a binding site for l-DNA.