SNAP output for PDB entry 7sr6 [SNAP web server]

PDB-id

7sr6; SNAP-derived features in text and JSON formats; DNAproDB

Class

replication

Method

X-ray (2.62 Å)

Summary

Human endogenous retrovirus (herv-k) reverse transcriptase ternary complex with dsDNA template primer and dntp

Reference

Baldwin ET, Gotte M, Tchesnokov EP, Arnold E, Hagel M, Nichols C, Dossang P, Lamers M, Wan P, Steinbacher S, Romero DL (2022): "Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition." Proc.Natl.Acad.Sci.USA, 119, e2200260119. doi: 10.1073/pnas.2200260119.

Abstract