SNAP output for PDB entry 7z2h [SNAP web server]

PDB-id

7z2h; SNAP-derived features in text and JSON formats; DNAproDB

Class

transferase

Method

cryo-EM (3.58 Å)

Summary

cryo-EM structure of nnrti resistant m184i-e138k mutant hiv-1 reverse transcriptase with a DNA aptamer in complex with doravirine

Reference

Singh AK, De Wijngaert B, Bijnens M, Uyttersprot K, Nguyen H, Martinez SE, Schols D, Herdewijn P, Pannecouque C, Arnold E, Das K (2022): "Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine." Proc.Natl.Acad.Sci.USA, 119, e2203660119. doi: 10.1073/pnas.2203660119.

Abstract