Summary information and primary citation
- PDB-id
- 8q7n; SNAP-derived features in text and JSON formats;
DNAproDB
- Class
- splicing
- Method
- cryo-EM (3.1 Å)
- Summary
- cryo-EM structure of the human spliceosomal b complex protomer (tri-snrnp core region)
- Reference
- Zhang Z, Kumar V, Dybkov O, Will CL, Urlaub H, Stark H, Luhrmann R (2024): "Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins." Embo J., 43, 1065-1088. doi: 10.1038/s44318-024-00052-1.
- Abstract
- The B complex is a key intermediate stage of spliceosome assembly. To improve the structural resolution of monomeric, human spliceosomal B (hB) complexes and thereby generate a more comprehensive hB molecular model, we determined the cryo-EM structure of B complex dimers formed in the presence of ATP
